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PRIAPISM: REPORT OF CASES AND A CLINICAL STUDY OF THE LITERATURE WITH REFERENCE TO ITS PATHOGENESIS AND SURGICAL TREATMENT 17863277 2007 09 17 2008 11 20 0003-4932 60 6 1914 Dec Annals of surgery Ann. Surg. PRIAPISM: REPORT OF CASES AND A CLINICAL STUDY OF THE LITERATURE WITH REFERENCE TO ITS PATHOGENESIS AND SURGICAL TREATMENT. 689-716 Hinman F F eng Journal Article United States Ann Surg 0372354 0003-4932 1914 12 1 0 0 1914 12 1 0 1 1914 12 1 0 0 ppublish 17863277 PMC1406528
Priapism - A New Approach to Management 5722542 1969 01 17 2008 11 20 0035-9157 61 11 Part 1 1968 Nov Proceedings of the Royal Society of Medicine Proc. R. Soc. Med. Priapism--a new approach to management. 1109 Bell W R WR Pitney W R WR eng Case Reports Journal Article England Proc R Soc Med 7505890 0035-9157 0 Venoms EC 3.4.- Peptide Hydrolases IM Adult Humans Male Peptide Hydrolases therapeutic use Priapism drug therapy etiology Thrombosis complications etiology Venoms therapeutic use Wounds
A prospective diary study of stuttering priapism in adolescents and young men with sickle cell anemia: report of an international randomized control trial--the priapism in sickle cell study. Priapism is defined as a prolonged, persistent, and purposeless penile erection. It is a common (35%) but frequently understated complication in young men and adults with sickle cell disease. We had previously demonstrated an association between stuttering attacks (<4 hours) and an acute catastrophic event (...) with its consequent problems of erectile dysfunction and impotence. We describe a randomized, placebo-controlled, clinical study looking at medical prophylaxis with 2 oral α-adrenergic agonists, etilefrine and ephedrine, in preventing stuttering attacks of priapism. One hundred thirty-one patients were registered into a 2-phase (observational and intervention phase) study, and 86 patients (66%) completed Phase A diary charts. Forty-six patients (59%) completed a 6-month treatment phase (Phase B
PriapismPriapism - Genitourinary Disorders - MSD Manual Professional Edition Brought to you by The trusted provider of medical information since 1899 SEARCH SEARCH MEDICAL TOPICS Common Health Topics Resources QUIZZES & CASES Quizzes Cases The trusted provider of medical information since 1899 SEARCH SEARCH MEDICAL TOPICS Common Health Topics Resources QUIZZES & CASES Quizzes Cases / / / / IN THIS TOPIC OTHER TOPICS IN THIS CHAPTER Test your knowledge Acute Tubular Necrosis Which (...) to Any Platform Loading , MD, David Geffen School of Medicine at UCLA Click here for Patient Education NOTE: This is the Professional Version. CONSUMERS: Topic Resources Priapism is painful, persistent, abnormal erection unaccompanied by sexual desire or excitation. It is most common in boys 5 to 10 yr and in men age 20 to 50 yr. Podcast Pathophysiology The penis is composed of 3 corporeal bodies: 2 corpora cavernosa and 1 corpus spongiosum. Erection is the result of smooth muscle relaxation
Priapism in acute spinal cord injury Emergency Medicine Blog: Priapism in acute spinal cord injury Sunday, June 16, 2013 Priapism in acute spinal cord injury Why priapism in acute spinal cord injury? The pathophysiology It is assumed that the mechanism of priapism in most patients with SCI is that abrupt loss of sympathetic input to the pelvic vasculature leads to increased parasympathetic input and uncontrolled arterial inflow directly into the penile sinusoidal spaces. The sympathetic outflow (...) arises from the thoracolumbar spine, that is, the spinal cord from approximately T2 to the conus (L1-2). The sympathetic outflow to the penis and clitoris arises from the lowest levels of the spinal cord, the conus, which is the reason why a lesion at any level in the spinal cord from the brainstem to the conus can be associated with priapism. (Ref: Keoghane SR, Sullivan ME, Miller MA. The aetiology, pathogenesis and management of priapism. BJU Int 2002; 90: 149–154.) Therefore, if a patient
Priapism following a lumbar sympathetic nerve block. To understand an unusual complication of a common procedure.This article chronicles the side effect of a lumbar sympathetic nerve block (LSNB).Loyola University Medical Center Outpatient Chronic Pain Clinic.One.Our patient had several hours of priapism following a LSNB.A bilateral lumbar sympathetic nerve block can lead to unopposed parasympathetic penile stimulation and cause priapism.Wiley Periodicals, Inc.
In vitro and in vivo animal models in priapism research. Priapism is an enigmatic yet devastating clinical phenomenon. In the last two decades, the use of various animal models to study this disorder has dramatically advanced our understanding of this mysterious disorder.This report reviews various animal models used to study ischemic priapism and informs basic science researchers the broad view of priapism research.Retrospective review of pertinent literature from the last two decades via (...) PubMed search using the keywords "ischemic priapism" and "priapism model." Findings on the animal models used in ischemic priapism research and its advantages and limitations.In vitro and in vivo animal models varying from dogs, cats, rabbits, rats to mice were used in priapism research. In vitro models included: (i) corpora cavernosa smooth muscle (CCSM) strip in organ bath; (ii) corporal tissue binding assay; (iii) CCSM cell culture under hypoxia/anoxia. In vivo models could be categorized as: (i
Penile necrosis due to priapism developed after circumcision in a patient with protein S deficiency. Hypercoagulable state is a complex condition with an abnormal propensity for thrombosis. The consequences of it due to thrombosis of veins and arteries are the most common cause of sickness.The present study is a report of a case describing penis necrosis after circumcision and evaluation of hypercoagulable state as a reason of it.l Nine-year-old boy referred from another hospital (...) with the sequelae of the penile ischemia with discoloration of the penis after traditional circumcision.The ischemic event developed 3 weeks after circumcision. Priapism that was treated with needed glandulocavernous shunt initially developed following circumcision. All values of routine blood count and blood biochemical analysis were within normal limits. Further, hematologic studies revealed that there might be a hypercoagulable state as a result of lower protein S level.Circumcision is a common procedure
High-flow priapism due to a malignant glomus tumor (glomangiosarcoma) of the corpus cavernosum. The major cause of non-ischemic high-flow priapism is post-traumatic vascular injury leading to an arterio-lacunar fistula. However, rare causes such as tumors may induce priapism. This is the first report of a malignant glomus tumor localized in the corpora cavernosa.The aim of this case is to emphasize the importance of the initial management of priapism and to suggest new tracks on the tests (...) to be performed when the usual exams are not sufficient.We report the case of a hypervascular penile tumor responsible for high-flow priapism as the first clinical symptom of a metastatic glomus tumor. The persistent penile tumescence was initially considered to be a stuttering priapism and treated using an oral α-adrenergic as no provoking event nor fistula was found. After a 2-week reluctance, a penile magnetic resonance imaging (MRI) was performed.The MRI showed a hypervascular lesion at the proximal part
Priapism in hematological and coagulative disorders: an update. Priapism is a true urological emergency that is typified by a persistent and painful erection. High-risk groups include patients with hematological or coagulative disorders; for example, those with sickle cell disease, leukemia or glucose-6-phosphate dehydrogenase deficiency. The diagnosis for priapism must be made urgently using patient history, physical examination and blood gas findings on corporal aspiration. Emergency (...) treatment is needed to avoid erectile dysfunction. However, in high-risk groups, prophylaxis must be encouraged. A number of prophylactic measures are emerging based on progress in the understanding of the pathophysiology of priapism in these particular patients. In this Review, priapism as it relates to hematological disorders is discussed, focusing on treatment and prophylaxis.
° 197); canakinumab in periodic fever syndromes (Prescrire Int n° 198); lopinavir + ritonavir oral solution for HIV-infected children from 14 days of age (Prescrire Int n° 198); everolimus in epilepsy associated with tuberous sclerosis complex (Prescrire Int n° 199); captopril oral solution (Rev Prescrire n° 418); etilefrine in priapism (Rev Prescrire n° 420); sofosbuvir alone or combined with ledipasvir for adolescents with chronic hepatitis C (Rev Prescrire n° 421); glecaprevir + pibrentasvir
significant acute complications such as acute chest syndrome, serious infections, stroke, renal necrosis, and priapism. 4 Chronic complications can emerge across multiple organs and include delayed puberty, avascular necrosis, skin ulcers, chronic pain, neurocognitive impairment, chronic kidney injury, pulmonary hypertension, cardiovascular disease, and can result in early mortality. 4 Resultant health care costs are high, with the total health system economic burden of SCD estimated at $2.98 billion per (...) unruly.” 6 We also heard patient testimony of young men being called perverts because they were experiencing priapism. The appearance of health, coupled with a lack of SCD awareness in patients’ broader communities, can lead to ignorant judgments of character. Patients who are unable to participate in their daily commitments at work or school due to unsurmountable fatigue, pain, or other complications, may be accused of laziness or be subject to bullying. Both children and their caregivers felt SCD
focal neurological signs priapism confusion or stupor history of chronic myelogenous leukaemia (CML) exposure to ionising radiation exposure to alkylating chemotherapeutic agents Diagnostic investigations FBC and differential peripheral blood smear bone marrow aspiration and biopsy karyotype fluorescent in situ hybridisation quantitative PCR serum leukocyte alkaline phosphatase serum vitamin B12 T315I gene mutation test Treatment algorithm ACUTE ONGOING Contributors Authors Professor of Medicine
and health among older adults in the United States. N Engl J Med, 2007. 357: 762. 2. Rosenberg, M.T., et al. Identification and diagnosis of premature ejaculation. Int J Clin Pract, 2007. 61: 903. 3. Tekgül, S., et al. European Association of Urology guidelines on Paediatric Urology. Edn. presented at the EAU Annual Congress London, 2017. 4. Montague, D.K., et al. American Urological Association guideline on the management of priapism. J Urol, 2003. 170: 1318. 5. Eland, I.A., et al. Incidence of priapism (...) in the general population. Urology, 2001. 57: 970. 6. Kulmala, R.V., et al. Priapism, its incidence and seasonal distribution in Finland. Scand J Urol Nephrol, 1995. 29: 93. 7. Furtado, P.S., et al. The prevalence of priapism in children and adolescents with sickle cell disease in Brazil. Int J Hematol, 2012. 95: 648. 8. Adeyoju, A.B., et al. Priapism in sickle-cell disease; incidence, risk factors and complications - an international multicentre study. BJU Int, 2002. 90: 898. 9. Emond, A.M., et al. Priapism