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81. Emergency Department Visits and Inpatient Admissions Associated with Priapism among Males with Sickle Cell Disease in the United States, 2006–2010 Full Text available with Trip Pro

Emergency Department Visits and Inpatient Admissions Associated with Priapism among Males with Sickle Cell Disease in the United States, 2006–2010 People with sickle cell disease (SCD) suffer from numerous acute complications that can result in multiple hospitalizations and emergency department (ED) and outpatient care visits. Priapism, a prolonged unwanted erection of the penis not due to sexual stimulation, is a serious complication among males with SCD. Variations in estimates (...) of prevalence make it difficult to accurately assess the burden of this complication of SCD. We analyzed data from the Nationwide Emergency Department Sample (NEDS), a product of the Healthcare Cost and Utilization Project, for the years 2006 through 2010 to measure the numbers of ED visits and to examine patterns of subsequent hospitalizations associated with priapism among male patients with SCD. We find that among ED visits associated with males with SCD, those prompted by priapism are more likely

2016 PloS one

82. Guideline of Guidelines Priapism. (Abstract)

Guideline of Guidelines Priapism. 27860090 2018 03 14 2018 03 14 1464-410X 119 2 2017 02 BJU international BJU Int. Guideline of guidelines: priapism. 204-208 10.1111/bju.13717 Muneer Asif A Departments of Urology, University College London Hospitals, London, UK. National Institute for Health Research (NIHR) Biomedical Research Centre, University College London Hospitals, London, UK. Ralph David D Departments of Andrology, University College London Hospitals, London, UK. St Peters Andrology (...) Centre, London, UK. eng Letter Research Support, Non-U.S. Gov't Review 2016 12 29 England BJU Int 100886721 1464-4096 0 Sympathomimetics N8ONU3L3PG Terbutaline YKH834O4BH Epinephrine IM Epinephrine therapeutic use Evidence-Based Medicine Humans Injections, Intralesional Male Practice Guidelines as Topic Priapism drug therapy physiopathology surgery therapy Prognosis Risk Assessment Severity of Illness Index Societies, Medical standards Sympathomimetics therapeutic use Terbutaline therapeutic use

2016 BJU international

83. Use of High-Dose Phenylephrine in the Treatment of Ischemic Priapism: Five-Year Experience at a Single Institution. (Abstract)

Use of High-Dose Phenylephrine in the Treatment of Ischemic Priapism: Five-Year Experience at a Single Institution. Ischemic priapism is an uncommon urologic emergency characterized by a compartment syndrome-like ischemic insult to the corpora cavernosa of the penis. The goal of treatment in ischemic priapism is rapid detumescence to prevent long-term erectile dysfunction. Non-surgical treatment options include aspiration, irrigation, and intracavernous injections of sympathomimetic agents (...) . At our institution, phenylephrine is used in the treatment of ischemic priapism at concentrations and doses that are higher than those recommended in established guidelines.To characterize our experience with high-concentration intracavernous phenylephrine in the treatment of ischemic priapism at an urban tertiary care center.A retrospective chart review identified 58 unique patients presenting to the emergency department on 136 occasions and receiving the diagnosis of ischemic priapism by urologic

2016 Journal Of Sexual Medicine

84. T-Shaped Shunt with Intracavernosal Tunneling, for a Pediatric Case of Refractory Ischemic Priapism. (Abstract)

T-Shaped Shunt with Intracavernosal Tunneling, for a Pediatric Case of Refractory Ischemic Priapism. We present the first reported case of refractory pediatric priapism treated by intracavernosal tunneling T shunt. A 12-year-old male, with sickle cell disease, presented with 72 hours of painful erection. The patient failed conservative measures including aspiration, injection of phenylephrine, as well as distal shunt procedure. A T-T shunt was performed, as previously described in the adult (...) literature. There was immediate resolution of the erection with no complications. At 1-year follow-up, he reports no subsequent episodes of priapism and normal erections. T shunt with tunneling can be performed in select cases of severe pediatric refractory ischemic priapism.Copyright © 2016 Elsevier Inc. All rights reserved.

2016 Urology

85. Priapism as the Presenting Manifestation of Multiple Myeloma Full Text available with Trip Pro

Priapism as the Presenting Manifestation of Multiple Myeloma 28194073 2018 11 13 0971-4502 33 1 2017 Mar Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion Indian J Hematol Blood Transfus Priapism as the Presenting Manifestation of Multiple Myeloma. 133-136 10.1007/s12288-016-0722-7 Sahu Kamal Kant KK Department of Internal Medicine, P.G.I.M.E.R, Union Territory of Chandigarh, 160012 India. Mishra Kundan K Department

2016 Indian Journal of Hematology & Blood Transfusion

86. High Flow Priapism in a Pediatric Patient after Circumcision with Dorsal Penile Nerve Block Full Text available with Trip Pro

High Flow Priapism in a Pediatric Patient after Circumcision with Dorsal Penile Nerve Block We report the first documented case of high flow priapism after circumcision with dorsal penile nerve block. A 7-year-old male who had undergone circumcision three years before presented to our institution with a 3-year history of persistent nonpainful erections. Workup revealed a high flow priapism and, after discussion of the management options, the patient's family elected continued observation.

2016 Case reports in pediatrics

87. Can Priapism Occur as an Idiosyncratic Reaction to Risperidone? Full Text available with Trip Pro

Can Priapism Occur as an Idiosyncratic Reaction to Risperidone? 28360796 2018 11 13 1300-0667 53 2 2016 Jun Noro psikiyatri arsivi Noro Psikiyatr Ars Can Priapism Occur as an Idiosyncratic Reaction to Risperidone? 186-187 10.5152/npa.2015.10296 Şenormanci Ömer Ö Department of Psychiatry, Bülent Ecevit University School of Medicine, Zonguldak, Turkey. Atasoy Nuray N Department of Psychiatry, Bülent Ecevit University School of Medicine, Zonguldak, Turkey. Konuk Numan N Department of Psychiatry

2016 Nöro Psikiyatri Arşivi

88. Beneficial Effect of the Nitric Oxide Donor Compound 3-(1,3-Dioxoisoindolin-2-yl)Benzyl Nitrate on Dysregulated Phosphodiesterase 5, NADPH Oxidase, and Nitrosative Stress in the Sickle Cell Mouse Penis: Implication for Priapism Treatment Full Text available with Trip Pro

Beneficial Effect of the Nitric Oxide Donor Compound 3-(1,3-Dioxoisoindolin-2-yl)Benzyl Nitrate on Dysregulated Phosphodiesterase 5, NADPH Oxidase, and Nitrosative Stress in the Sickle Cell Mouse Penis: Implication for Priapism Treatment Patients with sickle cell disease (SCD) display priapism, and dysregulated nitric oxide (NO) pathway may contribute to this condition. However, current therapies offered for the prevention of priapism in SCD are few. The 3-(1,3-dioxoisoindolin-2-yl)benzyl (...) and oxidative stress in erectile tissue. Wild-type, SCD, and dNOS-/- mice were treated with compound 4C (100 μmol/kg/d, 3 weeks). Intracavernosal pressure in anesthetized mice was evaluated. Corpus cavernosum tissue was dissected free and mounted in organ baths. SCD and dNOS-/- mice displayed a priapism phenotype, which was reversed by compound 4C treatment. Increased corpus cavernosum relaxant responses to acetylcholine and electrical-field stimulation were reduced by 4C in SCD mice. Likewise, increased

2016 The Journal of pharmacology and experimental therapeutics

89. Priapism as a new symptom of anaphylaxis in a prepubescent child. (Abstract)

Priapism as a new symptom of anaphylaxis in a prepubescent child. 27496320 2018 03 16 2018 12 02 1399-3038 27 8 2016 12 Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology Pediatr Allergy Immunol Priapism as a new symptom of anaphylaxis in a prepubescent child. 871-872 10.1111/pai.12618 Castilla-Hernández Eva E Pediatric Allergy Department, Hospital Universitari Vall d'Hebron, Barcelona, Spain. Garriga-Baraut Teresa T Pediatric (...) Allergy Department, Hospital Universitari Vall d'Hebron, Barcelona, Spain. eng Case Reports Letter 2016 09 16 England Pediatr Allergy Immunol 9106718 0905-6157 IM Anaphylaxis Child Humans Male Penis Priapism 2016 8 9 6 0 2018 3 17 6 0 2016 8 7 6 0 ppublish 27496320 10.1111/pai.12618

2016 Pediatric Allergy and Immunology

90. al-Ghorab Shunt for Priapism. (Abstract)

al-Ghorab Shunt for Priapism. The Surgical Techniques Section is sponsored in part by Coloplast.Copyright © 2016. Published by Elsevier Inc.

2016 Journal Of Sexual Medicine

91. Risk Factors for Priapism Readmission. (Abstract)

Risk Factors for Priapism Readmission. Priapism is a urologic emergency with a tendency to recur in some patients. The frequency of, time to, and risk factors for priapism recurrence have not been well characterized.To identify predictors of priapism readmission.We used the New York Statewide Planning and Research Cooperative System database to identify patients presenting to emergency departments with priapism from 2005 through 2014. Patients were tracked up to 12 months after initial (...) presentation. Proportional hazards regression was used to identify risk factors for priapism readmission.Readmissions for priapism.The analytic cohort included 3,372 men with a diagnosis of priapism. The average age at first presentation was 39 ± 18 years and 40% were black. Within 1 year, 24% of patients were readmitted for recurrent priapism, 68% of whom were readmitted within 60 days. On multivariate analysis, sickle cell disease (hazard ratio [HR] = 2.5, 95% CI = 2.0-3.0), drug abuse or psychiatric

2016 Journal Of Sexual Medicine

92. Prevention of Ischemic Priapism in Sickle Cell Disease: Sildenafil. (Abstract)

Prevention of Ischemic Priapism in Sickle Cell Disease: Sildenafil. 26431892 2016 04 21 2018 12 02 1527-9995 86 6 2015 Dec Urology Urology Prevention of Ischemic Priapism in Sickle Cell Disease: Sildenafil: Commentary on: Randomized Controlled Trial of Sildenafil for Preventing Recurrent Ischemic Priapism in Sickle Cell Disease. 1055-6 10.1016/j.urology.2015.07.003 S0090-4295(15)00650-0 Shakeri Aria A Division of Urology, Department of Surgery, University of Toronto, Toronto, Ontario, Canada (...) Phosphodiesterase 5 Inhibitors therapeutic use Piperazines therapeutic use Priapism etiology prevention & control Sulfones therapeutic use 2015 07 07 2015 07 07 2015 07 10 2015 10 4 6 0 2015 10 4 6 0 2016 4 22 6 0 ppublish 26431892 S0090-4295(15)00650-0 10.1016/j.urology.2015.07.003

2015 Urology Controlled trial quality: uncertain

93. Post-Traumatic High Flow Priapism: Multidetector Computed Tomography Demonstration. (Abstract)

Post-Traumatic High Flow Priapism: Multidetector Computed Tomography Demonstration. High-flow priapism due to pseudoaneurysm is a relatively rare urologic condition. Clear anatomic delineation of the number and origin of feeding vessels facilitates pre-embolization planning. Computed tomographic angiography can afford a three-dimensional display of the feeding vessels. We present a 26-year-old man with post-traumatic high-flow priapism, which is the first case studied with computed tomographic

2015 Urology

94. Subacute Hemolysis in Sickle Cell Mice Causes Priapism Secondary to NO Imbalance and PDE5 Dysregulation. Full Text available with Trip Pro

Subacute Hemolysis in Sickle Cell Mice Causes Priapism Secondary to NO Imbalance and PDE5 Dysregulation. Recent research suggests that priapism in sickle cell disease (SCD) is due to dysregulation of penile erection homeostasis including alteration of nitric oxide synthase (NOS) and phosphodiesterase type 5 (PDE5) activities by excessive levels of reactive oxygen species (ROS) released during hemolysis. It is unknown if subacute exposure to hemolysis is sufficient or if chronic reconditioning (...) of erectile tissues is required for perturbation of homeostatic pathways and whether PDE5 inhibitor (PDE5I) treatment can restore erectile homeostasis in the subacute setting.The aim of this study was to investigate the effects of subacute hemolysis (3-month exposure) on priapism and NO pathway regulation.Mice underwent bone marrow transplantation with either SCD (BM-SS) or wild-type (WT) bone marrow. BM-SS mice were treated with sildenafil 100 mg/kg/day. We measured intracavernous pressure (ICP

2015 Journal Of Sexual Medicine

95. Priapism – A Rare Presentation in Chronic Myeloid Leukemia: Case Report Full Text available with Trip Pro

Priapism – A Rare Presentation in Chronic Myeloid Leukemia: Case Report Priapism is a complication rarely seen in leukemia. We report a 19-year-old man presented with persistent painful erection of penis for over 24 hours at home. The patient had underwent immediate irrigation and decompression of priapism by urologist at emergency services of the hospital. This approach resulted in a flaccid penis later. During hospitalization, peripheral blood smear and bone marrow aspiration confirmed

2015 Urology case reports

96. Does pentoxifylline enhance the recovery of erectile function after a T-shunt procedure for prolonged ischaemic priapism? A prospective randomised controlled trial. Full Text available with Trip Pro

Does pentoxifylline enhance the recovery of erectile function after a T-shunt procedure for prolonged ischaemic priapism? A prospective randomised controlled trial. To evaluate the role of oral pentoxifylline for enhancing the recovery of erectile function (EF) in patients who had a T-shunt, a technically simple procedure for treating prolonged ischaemic priapism, as the recovery of EF has been reported in many patients treated by this procedure.This prospective randomised study was conducted (...) on 40 patients with prolonged ischaemic priapism treated with a T-shunt. Patients were randomly divided into two groups; group A received oral pentoxifylline from the second day after surgery for 3 months, and group B received placebo. Patients were followed for 18 months.The pain resolved in all patients, and EF recovered in 15 patients in group A and 10 in group B within 3 months. All patients but three had recovery of EF within the 18-month follow-up. Six patients had recovery of EF by using

2015 Arab journal of urology Controlled trial quality: uncertain

97. Trends in Sickle-Cell-Disease-Related Priapism in U.S. Children's Hospitals. Full Text available with Trip Pro

Trends in Sickle-Cell-Disease-Related Priapism in U.S. Children's Hospitals. To define rates of priapism diagnosis and inpatient admission among males with sickle cell disease (SCD).We retrospectively reviewed the Pediatric Health Information System database for males aged <21 years treated 2004-2012. We identified patients with SCD and priapism based on the International Classification of Diseases, Ninth Revision, Clinical Modification diagnosis codes. Logistic regression and generalized (...) estimating equation models were used to control for confounding and to adjust for within-hospital clustering of similar patients.We identified 17,186 males who were admitted 137,710 times during the study period. Of these, 362 (2.1%) were diagnosed with priapism on 748 admissions. There was a significant decrease in the number of priapism admissions among patients with SCD over time (0.81% in 2004 to 0.44% in 2012, P  <  .001). The number of patients diagnosed with SCD-related priapism varied over time

2015 Urology

98. Malleable penile prosthesis is a cost-effective treatment for refractory ischemic priapism. (Abstract)

Malleable penile prosthesis is a cost-effective treatment for refractory ischemic priapism. Refractory ischemic priapism (RIP) can be difficult to treat, consuming significant healthcare-related resources. Acute insertion of a malleable penile prosthesis (MPP) has been reported as an effective therapy that treats the priapism and restores sexual function.We report our 6-year, urban public hospital experience with acute insertion of MPP in patients with RIP.We retrospectively reviewed (...) the records of patients receiving MPPs for RIP from 2007 to 2013. Data analyzed included duration of erection, number of emergency room (ER) visits, hospital admissions, days of hospitalization, and postoperative course. Costs were estimated using standard Medicare reimbursement rates.Healthcare-related costs of treatment of RIP episodes in men presenting to our institution.During the study period, 14 men underwent MPP placement acutely for refractory priapism. Thirteen presented with RIP, and one had

2015 Journal Of Sexual Medicine

99. Erectile dysfunction after sickle cell disease-associated recurrent ischemic priapism: profile and risk factors. Full Text available with Trip Pro

Erectile dysfunction after sickle cell disease-associated recurrent ischemic priapism: profile and risk factors. Risk factors associated with erectile dysfunction (ED) that results from recurrent ischemic priapism (RIP) in sickle cell disease (SCD) are incompletely defined.This study aims to determine and compare ED risk factors associated with SCD and non-SCD-related "minor" RIP, defined as having ≥2 episodes of ischemic priapism within the past 6 months, with the majority (>75%) of episodes (...) lasting <5 hours.We performed a retrospective study of RIP in SCD and non-SCD patients presenting from June 2004 to March 2014 using the International Index of Erectile Function (IIEF), IIEF-5, and priapism-specific questionnaires.Prevalence rates and risk factor correlations for ED associated with RIP.The study was comprised of 59 patients (40 SCD [mean age 28.2 ± 8.9 years] and 19 non-SCD [15 idiopathic and four drug-related etiologies] [mean age 32.6 ± 11.7 years]). Nineteen of 40 (47.5%) SCD

2015 Journal Of Sexual Medicine

100. Penile Doppler ultrasound in men with stuttering priapism and sickle cell disease-a labile baseline diastolic velocity is a characteristic finding. (Abstract)

Penile Doppler ultrasound in men with stuttering priapism and sickle cell disease-a labile baseline diastolic velocity is a characteristic finding. Stuttering priapism (SP) is seen in sickle cell disease (SCD) and characterized by short-lived painful erections. Imbalanced vascular tone is the postulated cause and this may be reflected in changes in baseline penile blood flow as measured using penile Doppler ultrasound (PDU).The aim of this study was to investigate the baseline penile blood flow

2015 Journal Of Sexual Medicine

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