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Priapism

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21. The Hemodynamic Effects of Intracavernosal Phenylephrine for the Treatment of Ischemic Priapism. (Abstract)

The Hemodynamic Effects of Intracavernosal Phenylephrine for the Treatment of Ischemic Priapism. We sought to evaluate whether the administration of phenylephrine (PE) at concentrations higher than those described in guidelines resulted in any significant changes in vital signs or impacted outcomes.After receiving institutional review board approval, we retrospectively reviewed the charts of patients presenting to our emergency department between May 1, 2014, and August 15, 2016, using (...) International Classification of Diseases, Ninth Edition and Internation Classification of Disease, Tenth Edition diagnosis codes for priapism. Treatment was reviewed, including corporal aspiration/irrigation, injection of PE, and shunt procedures. Vital signs were compared before and after treatment with PE. Baseline variables were explored with categorical data analysis (chi-squared tests, t-tests, and Mann-Whitney nonparametric tests). Where feasible, linear regression was used to evaluate

2018 Journal Of Sexual Medicine

22. Emergency Management of Priapism in the United Kingdom: A Survey of Current Practice. (Abstract)

Emergency Management of Priapism in the United Kingdom: A Survey of Current Practice. Despite its importance, current practice in the emergency management of priapism in the United Kingdom is unknown.To evaluate current practice in the emergency management of priapism in the United Kingdom.All "full," "associate urological specialist," and "trainee" members of the British Association of Urological Surgeons (BAUS; leading membership-based organization for practitioners of urologic surgery (...) in the United Kingdom) were invited to participate in an online survey. Questions related to the emergency management of priapism, access to tertiary andrology services, and use of guidelines.Key outcome measures included frequency of encountered cases, access to specialist andrology support, confidence in key management steps, and use of current guidelines.213 of 1,304 (16.3%) eligible members completed the survey. Most reported managing 1 case annually (median = 1, range = 0->10). Only 7.0% transferred

2018 Journal Of Sexual Medicine

23. BAUS Consensus Document for the Management of Male Genital Emergencies - Priapism. Full Text available with Trip Pro

BAUS Consensus Document for the Management of Male Genital Emergencies - Priapism. Male genital emergencies relating to the penis and scrotum are rare and require prompt investigation and surgical intervention. Clinicians are often unfamiliar with the management of these conditions and may not work in a specialist centre with on-site expertise in genitourethral surgery. A series of consensus statements have been developed by an expert consensus committee comprising members of the BAUS Section (...)  of Andrology and Genitourethral Surgery together with experts from urology units throughout the UK. Priapism requires prompt assessment and treatment and these consensus statements provide guidance for UK practice.© 2018 The Authors BJU International © 2018 BJU International Published by John Wiley & Sons Ltd.

2018 BJU international

24. Poorly Controlled Homocystinuria: A Rare Cause of Ischemic Priapism? Full Text available with Trip Pro

Poorly Controlled Homocystinuria: A Rare Cause of Ischemic Priapism? We report on the 1st case of ischemic priapism secondary to poorly controlled homocystinuria. Homocystinuria is a rare, autosomal recessive, inherited disorder of metabolism that is caused by a deficiency of cystathionine synthase, leading to marked hyperhomocysteinemia. Arterial and/or venous thromboemboli are a major cause of mortality and morbidity in patients with homocystinuria. Untreated patients have a 50% chance (...) of having a vascular event by 30 years of age. Increased homocysteine levels have been reported to upregulate prothrombotic factors and downregulate antithrombotic factors; in particular, increased homocystinuria has been found to downregulate nitric oxide (NO). Mice that are deficient in NO synthase in the cavernosal smooth muscles have a higher incidence of priapism. Decrease in NO synthase causes downregulation of cyclic guanosine monophosphate, phosphodiesterase type 5A, and Rho A/Rho-kinase

2018 Sexual Medicine

25. Case — Temporary chemical castration in the management of recurrent priapism Full Text available with Trip Pro

Case — Temporary chemical castration in the management of recurrent priapism 29405906 2018 11 13 1911-6470 12 5 2018 May Canadian Urological Association journal = Journal de l'Association des urologues du Canada Can Urol Assoc J Case - Temporary chemical castration in the management of recurrent priapism. E265-E266 10.5489/cuaj.4875 Yi Yooni Y University of Michigan, Ann Arbor, MI, United States. Malaeb Bahaa B University of Michigan, Ann Arbor, MI, United States. eng Journal Article 2018 02

2018 Canadian Urological Association Journal

26. History of posttraumatic stress disorder · priapism · Dx? (Abstract)

History of posttraumatic stress disorder · priapism · Dx? A 35-year-old African-American man, who was an active duty service member, presented to the Troop Medical Clinic with a 4-hour history of priapism. He had been taking sertraline 100 mg and prazosin 10 mg nightly for 4 months to treat his posttraumatic stress disorder (PTSD) with no reported adverse effects. These doses were titrated 2 months prior to presentation. The patient reported that he took his usual medication doses before bed

2018 Journal of Family Practice

27. Posttraumatic High-Flow Nonischemic Priapism. (Abstract)

Posttraumatic High-Flow Nonischemic Priapism. Priapism is an uncommon disorder, and nonischemic priapism is seen less frequently in children, generally after trauma. Although it seems to be an advantage that urgent intervention is not required because of no cavernous ischemia, it is likely to be misdiagnosed because of the asymptomatic potential. We aimed to present a case of posttraumatic nonischemic priapism.

2018 Pediatric Emergency Care

28. Evaluation of sexual function in adult sicklers presenting with repeated attacks of ischaemic priapism in childhood

Evaluation of sexual function in adult sicklers presenting with repeated attacks of ischaemic priapism in childhood Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content of this registration record, any associated

2020 PROSPERO

29. Re.: A prospective diary study of stuttering priapism in adolescents and young men with sickle cell anemia: report of an international randomized control trial; the Priapism in Sickle Cell Study (PISCES study). (Abstract)

Re.: A prospective diary study of stuttering priapism in adolescents and young men with sickle cell anemia: report of an international randomized control trial; the Priapism in Sickle Cell Study (PISCES study). 22088730 2016 02 05 2018 12 01 1527-3792 185 5 2011 May The Journal of urology J. Urol. Re.: A prospective diary study of stuttering priapism in adolescents and young men with sickle cell anemia: report of an international randomized control trial; the Priapism in Sickle Cell Study (...) (PISCES study). 1837-8 10.1016/S0022-5347(11)60219-X Seftel Allen D AD eng Journal Article Comment United States J Urol 0376374 0022-5347 0 Adrenergic alpha-2 Receptor Agonists AIM IM J Androl. 2011 Jul-Aug;32(4):375-82 21127308 Adrenergic alpha-2 Receptor Agonists therapeutic use Anemia, Sickle Cell complications Humans Male Priapism drug therapy Stuttering complications 2011 11 18 6 0 2011 11 18 6 0 2016 2 6 6 0 ppublish 22088730 S0022-5347(11)60219-X 10.1016/S0022-5347(11)60219-X

2016 The Journal of urology Controlled trial quality: uncertain

30. Role of Penile Prosthesis in Priapism: A Review Full Text available with Trip Pro

Role of Penile Prosthesis in Priapism: A Review Ischemic priapism is a urological emergency that has been associated with long-standing and irreversible adverse effects on erectile function. Studies have demonstrated a linear relationship between the duration of critically ischemic episodes and the subsequent development of corporal fibrosis and irreversible erectile function loss. Placement of a penile prosthesis is a well-established therapeutic option for the management of erectile (...) dysfunction secondary to ischemic priapism, and will be the focus of this review. Review of the current literature demonstrates a growing utilization of penile prostheses in the treatment of erectile dysfunction secondary to ischemic priapism. Unfortunately, there is a paucity of randomized-controlled trials describing the use of prosthesis in ischemic priapism. As a result, there is a lack of consensus regarding the type of prosthesis (malleable vs. inflatable), timing of surgery (acute vs. delayed

2017 The world journal of men's health

31. Is there a relation between priapism occurring after penile doppler ultrasonography and international erectile function index score and erection hardness score levels? Full Text available with Trip Pro

Is there a relation between priapism occurring after penile doppler ultrasonography and international erectile function index score and erection hardness score levels? The relation between Erection Hardness Score (EHS) and The International Erectile Function Index (IIEF) Questionnaire- Erectile Function Domain Score (IIEF-EF score) used in erectile dysfunction (ED) evaluation and the prevalence of priapism after penile Doppler ultrasonography (PDU) was examined in this study.A total of 62 (...) patients who had PDU were included in the study. Patients were divided into two groups; there were 33 patients in IIEF-EF score ≤10, EHS <2 group (Group 1) and 29 patients in IIEF-EF score >10, EHS ≥2 group (Group 2). The two groups separated according to their scores were compared for age, body mass index (BMI), prevalence of priapism, vascular comorbidities and duration of erection.When compared to Group 2, median age, rate of vascular comorbidities rate and BMI were detected to be higher in Group 1

2017 Turkish journal of urology

32. Effect of lysyl oxidase (LOX) on corpus cavernous fibrosis caused by ischaemic priapism Full Text available with Trip Pro

Effect of lysyl oxidase (LOX) on corpus cavernous fibrosis caused by ischaemic priapism Penile fibrosis caused by ischemic priapism (IP) adversely affects patients' erectile function. We explored the role of lysyl oxidase (LOX) in rat and human penes after ischemic priapism (IP) to verify the effects of anti-LOX in relieving penile fibrosis and preventing erectile dysfunction caused by IP in rats. Seventy-two rats were randomly divided into six groups: control group, control + β

2017 Journal of cellular and molecular medicine

33. Three-piece Penile Prosthesis Implantation in Refractory Ischemic Priapism-Tips and Tricks. Full Text available with Trip Pro

Three-piece Penile Prosthesis Implantation in Refractory Ischemic Priapism-Tips and Tricks. Implantation of a penile prosthesis in a patient with significant corporal fibrosis can pose a significant challenge to the surgeon, necessitating the knowledge of specific techniques used to dilate and close aggressively scarred corpora. The objective of our instructional video is to discuss 2 techniques used to approach corporal fibrosis: proper and safe use of cavernotomes for dilation and use (...) of narrower prostheses.In this video, we present a 53-year-old man with a history of priapism 3 years ago that lasted 4 days in the setting of trazodone use. He was managed with corporal irrigation and subsequently developed severe erectile dysfunction. Notably, the patient had a history of sickle cell anemia, and on physical examination was noted to have densely fibrotic corpora. After extensive counseling regarding options, he chose a penile implant. The surgical was planned using the "no touch

2017 Urology

34. High-flow priapism treated with superselective transcatheter embolization using polyvinyl alcohol particles Full Text available with Trip Pro

High-flow priapism treated with superselective transcatheter embolization using polyvinyl alcohol particles Priapism is a persistent erection of the penis not associated with sexual stimulation. High-flow priapism is caused by unregulated arterial inflow, usually preceded by perineal or penile blunt trauma and formation of an arterial-lacunar fistula. We present a case of high-flow priapism in a 13-year-old patient managed with polyvinyl alcohol particles.After obtaining informed consent (...) for the treatment of high flow priapism without compromising erectile function.

2017 SAGE Open Medical Case Reports

35. Intracorporeal Dilatation Plus Al-Ghorab Corporoglandular Shunt for Salvage Management of Prolonged Ischemic Priapism Full Text available with Trip Pro

Intracorporeal Dilatation Plus Al-Ghorab Corporoglandular Shunt for Salvage Management of Prolonged Ischemic Priapism Ischemic priapism (IP) is a urological emergency that requires early intervention in order to prevent irreversible structural and functional changes. The purpose of penile shunt surgery is to passage out ischemic blood in the corpus cavernosum (CC), restoring the normal circulation within these structures. Here, we present our first experience using modification of Al-Ghorab (...) shunt procedure to treat severe and prolonged IP. The Al-Ghorab shunt procedure was modified by the retrograde insertion of a 7/8 Hegar dilator into the opening of the distal cavernous tissue via the original Al-Ghorab incision. Priapism was successfully relieved, and no recurrent IP was reported.

2017 Urology case reports

36. Conversion of Low-Flow Priapism to High-Flow State Using T-Shunt with Tunneling Full Text available with Trip Pro

Conversion of Low-Flow Priapism to High-Flow State Using T-Shunt with Tunneling Introduction. The three types of priapism are stuttering, arterial (high-flow, nonischemic), and venoocclusive (low-flow, ischemic). These are usually distinct entities and rarely occur in the same patient. T-shunts and other distal shunts are frequently combined with tunneling, but a seldom recognized potential complication is conversion to a high-flow state. Case Presentation. We describe 2 cases of men who (...) presented with low-flow priapism episodes that were treated using T-shunts with tunneling that resulted with both men having recurrent erections shortly after surgery that were found to be consistent with high-flow states. Case 1 was a 33-year-old male with sickle cell anemia and case 2 was a 24-year-old male with idiopathic thrombocytopenic purpura. In both cases the men were observed over several weeks and both men returned to normal erectile function. Conclusions. Historically, proximal shunts were

2017 Case reports in urology

37. Ischaemic priapism: A clinical review Full Text available with Trip Pro

Ischaemic priapism: A clinical review Ischaemic priapism is a rare condition characterised by little or no cavernosal blood flow, pain and rigidity of the penis. Immediate intervention is required to restore blood flow, prevent necrosis and erectile dysfunction. This review was conducted to determine the best course of treatment and identify areas in current guidelines to which improvements could be made.PubMed, Ovid, MEDLINE (1946-December 2016) and the Cochrane Library were searched (...) minimal cardiovascular side effects. It should be injected at a concentration of 100-500 μg/mL, with 1 mL being injected every 3-5 minutes for up to an hour (maximum 1mg in an hour). Surgical shunting is the next step, except in the cases of delayed priapism (48-72 hours duration) where immediate penile prosthesis insertion may be considered more appropriate. Distal shunts should be performed first, followed by proximal ones to minimise damage leading to erectile dysfunction. There exists little

2017 Turkish journal of urology

38. A Case Report of Priapism With Unusual Presentation and Clinical Course Full Text available with Trip Pro

A Case Report of Priapism With Unusual Presentation and Clinical Course This is a case report on a patient with an unusual presentation and clinical course of priapism. It further discusses treatment options with reflection on current literatures and guidelines. 48 year old patient presented with a history of more than 50 episodes of priapism, each lasting for five minutes. Patient had history of brain tumor that was resected and had since been in remission. On examination and further (...) biochemistry assessment revealed conflicting clinical findings, making it difficult to ascertain the type of priapism in this case. The patient, however, recovered from the acute attacks of priapism after 24 hours of conservative management and no obvious cause had been identified on post-discharge follow-up. Priapism, despite being rare, is a medical emergency. This case report reflected upon the limitations of treatment guidelines and the lack of level one evidence to support treatment decisions.

2017 Urology case reports

39. Advances in the understanding of priapism Full Text available with Trip Pro

Advances in the understanding of priapism Priapism, a persistent penile erection lasting longer than 4 hours and unrelated to sexual activity, is one of the most common emergencies treated by urologists. Priapism can be categorized as ischemic, recurrent ischemic (stuttering), and non-ischemic. Advances in understanding the pathophysiology of various types of priapism have led to targeted management strategies. This review aims to provide an up-to-date picture of the pathophysiology (...) and management of priapism. A search of Medline and PubMed for relevant publications using the term "priapism" was performed. In addition to the "classical" articles, emphasis was placed on publications from January 2013 to September 2016 to evaluate the most recent literature available. Though advances in both basic and clinical research continue and effective treatment options are available, methods for the prevention of priapism continue to be elusive.

2017 Translational andrology and urology

40. Challenges surrounding penile prostheses insertion following acute priapism Full Text available with Trip Pro

Challenges surrounding penile prostheses insertion following acute priapism 29239397 2019 01 18 2223-4691 6 Suppl 5 2017 Nov Translational andrology and urology Transl Androl Urol Challenges surrounding penile prostheses insertion following acute priapism. S804-S805 10.21037/tau.2017.11.19 Tatem Alex A Department of Urology, Indiana University, Indianapolis, Indiana, USA. Kovac Jason R JR Men's Health Center, Indianapolis, Indiana. eng Editorial Comment China Transl Androl Urol 101581119 2223

2017 Translational andrology and urology

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