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1. Long-Term Drug Therapy and Drug Holidays for Osteoporosis Fracture Prevention: A Systematic Review

, Los Angeles Los Angeles, CA Nancy Lane, M.D. Director and Distinguished Professor Center for Musculoskeletal Health and Department of Internal Medicine University of California at Davis, School of Medicine Sacramento, California Jasvinder Singh, M.D., M.P.H. Division of Rheumatology University of Alabama Birmingham, AL vii Long-Term Drug Therapy and Drug Holidays for Osteoporosis Fracture Prevention: A Systematic Review Structured Abstract Objective. To summarize the effects of long-term (...) Long-Term Drug Therapy and Drug Holidays for Osteoporosis Fracture Prevention: A Systematic Review Long-Term Drug Therapy and Drug Holidays for Osteoporosis Fracture Prevention: A Systematic Review Comparative Effectiveness Review Number 218 RComparative Effectiveness Review Number 218 Long-Term Drug Therapy and Drug Holidays for Osteoporosis Fracture Prevention: A Systematic Review Prepared for: Agency for Healthcare Research and Quality U.S. Department of Health and Human Services 5600

2019 Effective Health Care Program (AHRQ)

2. Using Clinical Laboratory Tests to Monitor Drug Therapy in Pain Management Patients

Tests to Monitor Drug Therapy in Pain Management Patients 7 drug testing as a primary prevention, diagnostic, and monitoring tool in the management of addiction or drug misuse in medical practice. While urine drug testing is currently regarded as the stan- dard for adherence monitoring of patients taking controlled substances to manage chronic pain, urine drug testing results are performed/read and interpreted by distinctly different sets of individuals. One group is clinical laboratory physicians (...) Using Clinical Laboratory Tests to Monitor Drug Therapy in Pain Management Patients LABORATORY MEDICINE PRACTICE GUIDELINES EDITED BY LORALIE J. LANGMAN AND PAUL J. JANNETTO Using Clinical Laboratory Tests to Monitor Drug Therapy in Pain Management Patients Co-Sponsored byLABORATORY MEDICINE PRACTICE GUIDELINES Using Clinical Laboratory Tests to Monitor Drug Therapy in Pain Management Patients Loralie J. Langman Committee Chair Department of Laboratory Medicine and Pathology Mayo Clinic

2018 American Academy of Pain Medicine

3. Drug Therapy for Early Rheumatoid Arthritis: A Systematic Review Update

? 128 Contextual Question 2: What barriers prevent individuals with early RA from obtaining access to indicated drug therapies? 128 Limitations 129 Research Needs 130 Conclusions 130 Abbreviations and Acronyms 131 Report References Ref-1 Tables Table A. Summary of characteristics of this systematic review on treatment of patients with early rheumatoid arthritis ES-1 Table B. Benefits and harms of csDMARDs versus csDMARD or tsDMARD for treatment of patients with early rheumatoid arthritis ES-6 Table (...) , demographics, or presence of other diseases with or without treatment). Additional details about this systematic review are described in Table A. Two Contextual Questions were also examined: (1) Does treatment of early RA improve disease trajectory and disease outcomes compared with the trajectory or outcomes of treatment of established RA? And (2) What barriers prevent individuals with early RA from obtaining access to indicated drug therapies? We synthesized the literature qualitatively within

2018 Effective Health Care Program (AHRQ)

4. Newer Drugs for Type 2 Diabetes: An Emerging Adjunctive Therapy to Insulin for Type 1 Diabetes?

Diabetes Canada, have acknowledged that there may be a role for adjunctive therapy in some T1D patients. 10,23,40 In the US, pramlintide acetate injection (Symlin) is the only noninsulin drug approved for adjunctive treatment of T1D. 13,29 Metformin, a T2D medication, is mentioned by Diabetes Canada and the American Diabetes Association for off-label use to reduce insulin requirements and total cholesterol/low-density lipoprotein ratios, 10,17,23 with the caveat that it does not improve hemoglobin A1C (...) Newer Drugs for Type 2 Diabetes: An Emerging Adjunctive Therapy to Insulin for Type 1 Diabetes? Newer Drugs for Type 2 Diabetes: An Emerging Adjunctive Therapy to Insulin for Type 1 Diabetes? | CADTH.ca CADTH Document Viewer Newer Drugs for Type 2 Diabetes: An Emerging Adjunctive Therapy to Insulin for Type 1 Diabetes? Table of Contents Search this document Newer Drugs for Type 2 Diabetes: An Emerging Adjunctive Therapy to Insulin for Type 1 Diabetes? January 2018 Summary There are two major

2018 CADTH - Issues in Emerging Health Technologies

5. Transcranial Direct Current Stimulation (tDCS) Cost-utility-analysis in Medical Care on Depressive Episode With One Drug Therapy Failure.

Transcranial Direct Current Stimulation (tDCS) Cost-utility-analysis in Medical Care on Depressive Episode With One Drug Therapy Failure. Transcranial Direct Current Stimulation (tDCS) Cost-utility-analysis in Medical Care on Depressive Episode With One Drug Therapy Failure. - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study (...) Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Transcranial Direct Current Stimulation (tDCS) Cost-utility-analysis in Medical Care on Depressive Episode With One Drug Therapy Failure. (DISCO) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health

2018 Clinical Trials

6. General medicine: Hormone therapy should not be prescribed for primary prevention of chronic medical conditions in asymptomatic postmenopausal women

General medicine: Hormone therapy should not be prescribed for primary prevention of chronic medical conditions in asymptomatic postmenopausal women Hormone therapy should not be prescribed for primary prevention of chronic medical conditions in asymptomatic postmenopausal women | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use (...) postmenopausal women Article Text Commentary General medicine Hormone therapy should not be prescribed for primary prevention of chronic medical conditions in asymptomatic postmenopausal women Catriona Hilton 1 , Henry Boardman 2 Statistics from Altmetric.com Commentary on: Gartlehner G, Patel SV, Feltner C, et al . Hormone Therapy for the Primary Prevention of Chronic Conditions in Postmenopausal Women: Evidence Report and Systematic Review for the US Preventive Services Task Force. JAMA 2017;318:2234–2249

2018 Evidence-Based Medicine

7. American Gastroenterological Association Institute Guideline on the Prevention and Treatment of Hepatitis B Virus Reactivation During Immunosuppressive Drug Therapy Full Text available with Trip Pro

Institute Guideline on the Prevention and Treatment of Hepatitis B Virus Reactivation During Immunosuppressive Drug Therapy K. Rajender Reddy Affiliations Division of Gastroenterology and Hepatology, University of Pennsylvania, Philadelphia, Pennsylvania Kimberly L. Beavers Affiliations Division of Gastroenterology and Hepatology, Medical University of South Carolina, Charleston, South Carolina Sarah P. Hammond Affiliations Division of Infectious Diseases, Brigham & Women’s Hospital, Dana-Farber Cancer (...) guidelines we can trust. Institute of Medicine , Washington, DC 2011 GRADE methodology was used to prepare the background information for the guideline and the technical review that accompanies it ( ). Perrillo R.P. Gish R. Falck-Ytter Y.T. American Gastroenterological Association Institute technical review on prevention and treatment of hepatitis B virus reactivation during immunosuppressive drug therapy. Gastroenterology. 2015; 148 : 221-244 Optimal understanding of this guideline will be enhanced

2015 American Gastroenterological Association Institute

8. Functional Family Therapy (FFT) for Young People in Treatment for Non?opioid Drug Use: A Systematic Review Full Text available with Trip Pro

version of this article with your friends and colleagues. Copy URL Share a link Share on 1 The terms ‘use’, ‘abuse’ and ‘dependence’ are often used interchangeably and refer to an addiction stage of non‐medical drug usage. of the kind that persists beyond the experimentation phase is a severe problem worldwide ( ). Abuse of non‐opioid drugs such as cannabis, amphetamine and cocaine is strongly associated with a broad range of negative health implications such as traffic accidents, sexually transmitted (...) Functional Family Therapy (FFT) for Young People in Treatment for Non?opioid Drug Use: A Systematic Review Functional Family Therapy (FFT) for Young People in Treatment for Non‐opioid Drug Use: A Systematic Review - Filges - 2015 - Campbell Systematic Reviews - Wiley Online Library By continuing to browse this site, you agree to its use of cookies as described in our . Search within Search term Search term SYSTEMATIC REVIEW Open Access Functional Family Therapy (FFT) for Young People

2015 Campbell Collaboration

9. Cognitive?Behavioural Therapies for Young People in Outpatient Treatment for Non?Opioid Drug Use: A Systematic Review Full Text available with Trip Pro

below to share a full-text version of this article with your friends and colleagues. Copy URL Share a link Share on 1 The terms use, abuse and dependence are used interchangeably throughout the review and refer to an addiction stage of non‐medical usage. that persists beyond curious experimentation is a severe problem worldwide ( ). Drugs such as cannabis, amphetamines, ecstasy and cocaine, referred to in this review as non‐opioids 2 Use of ketamine, nitrous oxide and inhalants, e.g. glue and petrol (...) Cognitive?Behavioural Therapies for Young People in Outpatient Treatment for Non?Opioid Drug Use: A Systematic Review Cognitive‐Behavioural Therapies for Young People in Outpatient Treatment for Non‐Opioid Drug Use: A Systematic Review - Filges - 2015 - Campbell Systematic Reviews - Wiley Online Library By continuing to browse this site, you agree to its use of cookies as described in our . Search within Search term Search term SYSTEMATIC REVIEW Open Access Cognitive‐Behavioural Therapies

2015 Campbell Collaboration

10. Multidimensional Family Therapy (MDFT) for Young People in Treatment for Non?opioid Drug Abuse: A Systematic Review Full Text available with Trip Pro

Multidimensional Family Therapy (MDFT) for Young People in Treatment for Non?opioid Drug Abuse: A Systematic Review Multidimensional Family Therapy (MDFT) for Young People in Treatment for Non‐opioid Drug Abuse: A Systematic Review - Filges - 2015 - Campbell Systematic Reviews - Wiley Online Library By continuing to browse this site, you agree to its use of cookies as described in our . Search within Search term Search term SYSTEMATIC REVIEW Open Access Multidimensional Family Therapy (MDFT (...) ) for Young People in Treatment for Non‐opioid Drug Abuse: A Systematic Review First published: 02 March 2015 Corresponding authorTrine FilgesSFI CampbellSFI ‐ The Danish National Centre for Social ResearchHerluf Trollesgade 111052 Copenhagen KDenmarkTelephone: +45 33 09 26E‐mail: Linked article: . Give access Share full text access Please review our and check box below to share full-text version of article. I have read and accept the Wiley Online Library Terms and Conditions of Use. Shareable Link Use

2015 Campbell Collaboration

11. Psychological interventions: Preventive cognitive therapy could be a viable and effective addition to antidepressant medication in preventing relapse or recurrence in major depressive disorder

Psychological interventions: Preventive cognitive therapy could be a viable and effective addition to antidepressant medication in preventing relapse or recurrence in major depressive disorder Preventive cognitive therapy could be a viable and effective addition to antidepressant medication in preventing relapse or recurrence in major depressive disorder | Evidence-Based Mental Health Log in using your username and password For personal accounts OR managers of institutional accounts Username (...) * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Preventive cognitive therapy could be a viable and effective addition to antidepressant medication in preventing relapse or recurrence in major depressive disorder Article Text Commentary Psychological interventions Preventive cognitive therapy

2019 Evidence-Based Mental Health

12. Randomised controlled trial: Coronary-artery bypass surgery plus medical therapy is associated with longer survival over 10?years than medical therapy alone in patients with ischaemic cardiomyopathy

Randomised controlled trial: Coronary-artery bypass surgery plus medical therapy is associated with longer survival over 10?years than medical therapy alone in patients with ischaemic cardiomyopathy Coronary-artery bypass surgery plus medical therapy is associated with longer survival over 10 years than medical therapy alone in patients with ischaemic cardiomyopathy | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can (...) bypass surgery plus medical therapy is associated with longer survival over 10 years than medical therapy alone in patients with ischaemic cardiomyopathy Article Text Therapeutics/Prevention Randomised controlled trial Coronary-artery bypass surgery plus medical therapy is associated with longer survival over 10 years than medical therapy alone in patients with ischaemic cardiomyopathy Akira Marui Correspondence to Dr Akira Marui, 69–306 Okazaki-Ten'no, Sakyo, Kyoto 606-8335 Japan; akiramarui78

2017 Evidence-Based Medicine

13. Effect of Preventional Drug Therapy on Pain Regulation Mechanisms Among SCI

will be received at the end of the study, or if the subjects for any reason participate in the research Primary Purpose: Treatment Official Title: The Effect of Preventional Drug Therapy on Pain Regulation Mechanisms Among Spinal Cord Injury Patients Who Have Yet to Develop Central Pain Actual Study Start Date : August 23, 2018 Estimated Primary Completion Date : November 2019 Estimated Study Completion Date : November 2019 Resource links provided by the National Library of Medicine related topics: available (...) Effect of Preventional Drug Therapy on Pain Regulation Mechanisms Among SCI Effect of Preventional Drug Therapy on Pain Regulation Mechanisms Among SCI - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Effect

2018 Clinical Trials

14. Randomised controlled trial: Prolonged dual antiplatelet therapy after drug-eluting stent reduces the risk of stent thrombosis and major cardiovascular events but increases the rate of bleeding

Randomised controlled trial: Prolonged dual antiplatelet therapy after drug-eluting stent reduces the risk of stent thrombosis and major cardiovascular events but increases the rate of bleeding Prolonged dual antiplatelet therapy after drug-eluting stent reduces the risk of stent thrombosis and major cardiovascular events but increases the rate of bleeding | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your (...) therapy after drug-eluting stent reduces the risk of stent thrombosis and major cardiovascular events but increases the rate of bleeding Article Text Therapeutics/Prevention Randomised controlled trial Prolonged dual antiplatelet therapy after drug-eluting stent reduces the risk of stent thrombosis and major cardiovascular events but increases the rate of bleeding Gérard Helft Statistics from Altmetric.com Commentary on : Mauri L , Kereiakes DJ , Yeh RW , et al , ; DAPT Study Investigators . Twelve

2015 Evidence-Based Medicine

15. Therapeutic Drug Monitoring During Induction of Anti-Tumor Necrosis Factor Therapy in Inflammatory Bowel Disease: Defining a Therapeutic Drug Window. Full Text available with Trip Pro

involved in secondary loss of response. Pharmacokinetic issues are linked to undetectable or subtherapeutic drug concentrations because of either an accelerated non-immune-mediated clearance or immunogenicity and the development of antidrug antibodies, whereas pharmacodynamic issues are likely related to "non-TNF driven" disease. Therapeutic drug monitoring (TDM), defined as the evaluation of drug concentrations and antidrug antibodies, has been proven effective for optimizing anti-TNF therapy in IBD (...) . Nevertheless, most of the data for TDM relate to patients losing response during maintenance therapy, whereas much less is known about the therapeutic drug window and use of TDM during anti-TNF induction therapy. Recent exposure-response relationship studies, though, demonstrate that high serum anti-TNF drug concentrations during and early after induction therapy are associated with favorable therapeutic outcomes in IBD. This suggests that early optimization of anti-TNF therapy may prevent some

2017 Inflammatory Bowel Diseases

16. Brief Strategic Family Therapy (BSFT) for Young People in Treatment for Non?Opioid Drug Use: A Systematic Review Full Text available with Trip Pro

). . 1.2 DESCRIPTION OF THE INTERVENTION BSFT is a manual‐based, family‐oriented prevention and treatment intervention that targets a young person's drug use. It is a problem focused family therapy, aiming at creating changes in those interactions relevant to the identified problems within families, and in individual family members who appear particularly resistant to change. BSFT is a family therapy approach that targets young people and their families as a system throughout the treatment, and thereby (...) Brief Strategic Family Therapy (BSFT) for Young People in Treatment for Non?Opioid Drug Use: A Systematic Review Brief Strategic Family Therapy (BSFT) for Young People in Treatment for Non‐Opioid Drug Use: A Systematic Review - Lindstrøm - 2013 - Campbell Systematic Reviews - Wiley Online Library By continuing to browse this site, you agree to its use of cookies as described in our . Search within Search term Search term SYSTEMATIC REVIEW Open Access Brief Strategic Family Therapy (BSFT

2013 Campbell Collaboration

17. Pacemaker Therapy for Drug-refractory Symptoms in Mid-cavity Hypertrophic Cardiomyopathy

and Intraventricular Gradient Reduction for Symptomatic Relief in Drug Refractory Hypertrophic Cardiomyopathy Patients With Mid-cavity Obstruction Actual Study Start Date : February 9, 2018 Estimated Primary Completion Date : February 2021 Estimated Study Completion Date : June 2021 Resource links provided by the National Library of Medicine related topics: related topics: resources: Arms and Interventions Go to Arm Intervention/treatment Experimental: Active pacing Active ventricular pacing. The pacemaker is set (...) Pacemaker Therapy for Drug-refractory Symptoms in Mid-cavity Hypertrophic Cardiomyopathy Pacemaker Therapy for Drug-refractory Symptoms in Mid-cavity Hypertrophic Cardiomyopathy - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies

2018 Clinical Trials

18. Therapeutic Drug Monitoring for Individualized Clozapine Therapy

Study Completion Date : December 31, 2020 Resource links provided by the National Library of Medicine related topics: related topics: available for: Groups and Cohorts Go to Intervention Details: Drug: Clozapine Clozapine is administered orally according to individual prescribed dosing regimens. Other Name: Clozapine treatment Outcome Measures Go to Primary Outcome Measures : Glucose and lipid metabolism abnormality [ Time Frame: Change from baseline glucose and lipid profiles on Day 15, and 57 (...) Therapeutic Drug Monitoring for Individualized Clozapine Therapy Therapeutic Drug Monitoring for Individualized Clozapine Therapy - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Therapeutic Drug Monitoring

2018 Clinical Trials

19. A Couple-based Antiretroviral Therapy Adherence Intervention for People Who Inject Drugs

A Couple-based Antiretroviral Therapy Adherence Intervention for People Who Inject Drugs A Couple-based Antiretroviral Therapy Adherence Intervention for People Who Inject Drugs - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies (...) before adding more. A Couple-based Antiretroviral Therapy Adherence Intervention for People Who Inject Drugs The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT03555396 Recruitment Status : Not yet recruiting First Posted

2018 Clinical Trials

20. Increases in CD4<sup>+</sup> T-cell count at antiretroviral therapy initiation among HIV-positive illicit drug users during a treatment-as-prevention initiative in Canada. Full Text available with Trip Pro

Increases in CD4+ T-cell count at antiretroviral therapy initiation among HIV-positive illicit drug users during a treatment-as-prevention initiative in Canada. Although treatment-as-prevention (TasP) efforts are a new cornerstone of efforts to respond to the HIV/AIDS pandemic, their effects among people who use drugs (PWUD) have not been fully evaluated. This study characterizes temporal trends in CD4+ T-cell (CD4) count at ART initiation and rates of virological response among HIV (...) -positive PWUD during a TasP initiative.We used data on individuals initiating ART within a prospective cohort of PWUD linked to comprehensive clinical records. Using multivariable linear regression, we evaluated the relationship between CD4 count prior to ART initiation and year of initiation and time to HIV-1 RNA viral load <50 copies/ml following initiation using Cox proportional hazards modelling.Among 355 individuals, CD4 count at initiation rose from 130 to 330 cells/ml from 2005 to 2013

2017 Antiviral Therapy

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