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Prenatal Vitamin

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141. Optimizing Periconceptional and Prenatal Folic Acid Supplementation

Library of Medicine related topics: available for: Arms and Interventions Go to Arm Intervention/treatment Experimental: PregVit-Folic 5®-5 mg folic acid Prenatal multivitamin-mineral supplement called PregVit-folic 5® contains 5 mg of folic acid. All other vitamin and mineral doses are identical between the 2 supplements, except for folic acid. Both supplements are taken as 2 tablets daily, one tablet in the morning (am) and one tablet in the evening (pm). Both multivitamins are appropriate (...) . All other vitamin and mineral doses are identical between the 2 supplements, except for folic acid. Both supplements are taken as 2 tablets daily, one tablet in the morning (am) and one tablet in the evening (pm). Both multivitamins are appropriate for periconceptional, prenatal, and post-partum supplementation. Drug: PregVit® contains 1.1 mg of folic acid Participants are randomly allocated to one of two groups: PregVit-Folic 5® (group1) contains 5 mg folic acid or PregVit® (group 2) contains 1.1

2014 Clinical Trials

142. Provider Adherence to Recommended Prenatal Care Content: Does It Differ for Obese Women? (PubMed)

-income, minority women from 2003 to 2004. Sample content items included procedures delivered at every visit (blood pressure, urinalysis, maternal weight, fetal heart rate check), timed screenings for birth defects and gestational diabetes, prenatal vitamin prescriptions, and depression screening. Weight gain, preterm deliveries, cesareans, and birthweight were compared between obese women with low and medium versus high adherence to PNC content using multivariable logistic regression. High provider (...) Provider Adherence to Recommended Prenatal Care Content: Does It Differ for Obese Women? The objective of this study was to examine provider adherence to prenatal care (PNC) content in obese and non-obese women and perinatal outcomes in obese women experiencing low and medium versus high adherence to PNC content. Provider adherence to PNC content (low <50%, medium 50-79%, and high ≥80%) was compared between obese (n = 69) and non-obese (n = 128) women in a linked database of deliveries to low

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2014 Maternal and child health journal

143. Maternal Fetal Attachment, Locus of Control and Adherence to STI/HIV Prevention and Prenatal Care Promotion Behaviors in Urban Women (PubMed)

this is beneficial, pregnant women in non-monogamous relationships may discount the importance of condom use during pregnancy. Prenatal care providers can provide education about condom use as a beneficial prenatal care behavior similar to taking prenatal vitamins. (...) Maternal Fetal Attachment, Locus of Control and Adherence to STI/HIV Prevention and Prenatal Care Promotion Behaviors in Urban Women Young women of childbearing age are disproportionately affected by sexually transmitted infections (STIs) including HIV. In particular, young women have more frequent and more serious health problems from STI or HIV infection than men, and among women, African American women have especially high rates of infection. Pregnancy is an important time for beginning

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2014 International journal of gynecological obstetrical and reproductive medicine research

144. Prenatal Nutrition (Treatment)

is not recommended. Both iron and copper compete with zinc at absorption sites. Zinc supplementation is recommended when elemental iron supplementation exceeds 60 mg/d. Likewise, whenever zinc supplements are used, copper should also be supplemented. Different prenatal vitamin formulations contain different amounts of copper and zinc. Usually, copper or zinc supplementation can be accomplished by appropriate selection of a prenatal vitamin formulation. [ ] Sodium Sodium is present in large quantities (...) in the average American diet. The RDA is 1.5 mg during pregnancy, lactation, and the non-pregnant state. Whether pregnant or not, sodium should neither be restricted nor used excessively. [ ] Well-balanced diets "salted to taste" satisfy sodium requirements and obviate any need for supplementation. Pregnant women should be counseled that most processed and pre-prepared foods are high in sodium. [ ] Previous Next: Prenatal Vitamin Supplements A standard prenatal vitamin formulation contains: Iron - 30 mg Zinc

2014 eMedicine.com

145. Prenatal Nutrition (Overview)

is not recommended. Both iron and copper compete with zinc at absorption sites. Zinc supplementation is recommended when elemental iron supplementation exceeds 60 mg/d. Likewise, whenever zinc supplements are used, copper should also be supplemented. Different prenatal vitamin formulations contain different amounts of copper and zinc. Usually, copper or zinc supplementation can be accomplished by appropriate selection of a prenatal vitamin formulation. [ ] Sodium Sodium is present in large quantities (...) in the average American diet. The RDA is 1.5 mg during pregnancy, lactation, and the non-pregnant state. Whether pregnant or not, sodium should neither be restricted nor used excessively. [ ] Well-balanced diets "salted to taste" satisfy sodium requirements and obviate any need for supplementation. Pregnant women should be counseled that most processed and pre-prepared foods are high in sodium. [ ] Previous Next: Prenatal Vitamin Supplements A standard prenatal vitamin formulation contains: Iron - 30 mg Zinc

2014 eMedicine.com

146. Prenatal Nutrition (Follow-up)

is not recommended. Both iron and copper compete with zinc at absorption sites. Zinc supplementation is recommended when elemental iron supplementation exceeds 60 mg/d. Likewise, whenever zinc supplements are used, copper should also be supplemented. Different prenatal vitamin formulations contain different amounts of copper and zinc. Usually, copper or zinc supplementation can be accomplished by appropriate selection of a prenatal vitamin formulation. [ ] Sodium Sodium is present in large quantities (...) in the average American diet. The RDA is 1.5 mg during pregnancy, lactation, and the non-pregnant state. Whether pregnant or not, sodium should neither be restricted nor used excessively. [ ] Well-balanced diets "salted to taste" satisfy sodium requirements and obviate any need for supplementation. Pregnant women should be counseled that most processed and pre-prepared foods are high in sodium. [ ] Previous Next: Prenatal Vitamin Supplements A standard prenatal vitamin formulation contains: Iron - 30 mg Zinc

2014 eMedicine.com

147. Prenatal Nutrition (Diagnosis)

is not recommended. Both iron and copper compete with zinc at absorption sites. Zinc supplementation is recommended when elemental iron supplementation exceeds 60 mg/d. Likewise, whenever zinc supplements are used, copper should also be supplemented. Different prenatal vitamin formulations contain different amounts of copper and zinc. Usually, copper or zinc supplementation can be accomplished by appropriate selection of a prenatal vitamin formulation. [ ] Sodium Sodium is present in large quantities (...) in the average American diet. The RDA is 1.5 mg during pregnancy, lactation, and the non-pregnant state. Whether pregnant or not, sodium should neither be restricted nor used excessively. [ ] Well-balanced diets "salted to taste" satisfy sodium requirements and obviate any need for supplementation. Pregnant women should be counseled that most processed and pre-prepared foods are high in sodium. [ ] Previous Next: Prenatal Vitamin Supplements A standard prenatal vitamin formulation contains: Iron - 30 mg Zinc

2014 eMedicine.com

148. Randomized controlled trial (RCT) of vitamin D supplementation in pregnancy in a population with endemic vitamin D deficiency. (PubMed)

Randomized controlled trial (RCT) of vitamin D supplementation in pregnancy in a population with endemic vitamin D deficiency. Vitamin D (vD) deficiency in pregnancy is a global health problem and the amount of vD supplementation to prevent vD deficiency is controversial.The objective of the study was to determine effectiveness and safety of prenatal 2000 IU and 4000 IU/d compared with 400 IU/d vD3 supplementation in a randomized controlled trial in population in which vD deficiency

2013 Journal of Clinical Endocrinology and Metabolism Controlled trial quality: predicted high

149. Randomized controlled trial (RCT) of vitamin D supplementation in pregnancy in a population with endemic vitamin D deficiency. (PubMed)

Randomized controlled trial (RCT) of vitamin D supplementation in pregnancy in a population with endemic vitamin D deficiency. Vitamin D (vD) deficiency in pregnancy is a global health problem and the amount of vD supplementation to prevent vD deficiency is controversial.The objective of the study was to determine effectiveness and safety of prenatal 2000 IU and 4000 IU/d compared with 400 IU/d vD3 supplementation in a randomized controlled trial in population in which vD deficiency

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2013 The Journal of clinical endocrinology and metabolism Controlled trial quality: predicted high

150. Effect of Vitamin D Replacement on Maternal and Neonatal Outcomes

) recommends 600 IU of vitamin D per day to reach a 25-Hydroxyvitamin D (25(OH)D) level ≥ 20 ng/ml, the Endocrine Society (ES) recommends 1,500-2,000 IU/day to reach a level ≥ 30 ng/ml, and the WHO guidelines do not recommend any supplementation as part of routine prenatal care. They do however underscore the fact that subjects with the lowest levels may be the ones to benefit most from vitamin D replacement. The benefits of such an approach and the doses needed to reach desirable levels have not been (...) years Vitamin D supplementation ≤ 200 IU daily (If daily vitamin D supplementation > 200 IU daily, at enrollment, the pregnant women will be advised to adjust prenatal multivitamin doses in such a way that total vitamin D supplementation per week doesn't exceed 1400 IU per week, in consultation with primary Obstetric and Gynecology (OB-GYN) physician.) Exclusion Criteria: 25(OH)D level < 10 ng/ml or > 30 ng/ml. Known metabolic bone disease Current medications likely to interfere with vitamin D

2015 Clinical Trials

151. Vitamin D deficiency in BALB/c mouse pregnancy increases placental transfer of glucocorticoids. (PubMed)

the fetus from inappropriate glucocorticoid exposure. There was a corresponding increase in placental and fetal expression of the highly glucocorticoid-sensitive factor glucocorticoid-induced leucine zipper. Furthermore, placental expression of the angiogenic factor vascular endothelial growth factor-A was reduced in vitamin D-deficient pregnancies, with a corresponding decline in fetal capillary volume within the placenta. Overall, we show that prenatal vitamin D deficiency leads to an increase (...) Vitamin D deficiency in BALB/c mouse pregnancy increases placental transfer of glucocorticoids. The prevalence of vitamin D deficiency in pregnancy is increasing and implicated in adverse consequences for the health of offspring in later life. The aim of this study was to determine whether vitamin D deficiency increases fetal exposure to glucocorticoids, which are known to alter fetal development and result in adverse adult health outcomes. Female BALB/c mice were placed on either a vitamin D

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2015 Endocrinology

152. Maternal and Pediatric Health Outcomes in relation to Gestational Vitamin D Sufficiency (PubMed)

disease, securing vitamin D sufficiency in pregnancy appears to be a simple, safe, and cost-effective measure that can be incorporated into routine preconception and prenatal care in the offices of primary care clinicians. Education on gestational nutritional requirements should be a fundamental part of medical education and residency training, instruction that has been sorely lacking to date. (...) Maternal and Pediatric Health Outcomes in relation to Gestational Vitamin D Sufficiency Juxtaposed with monumental improvement in maternal-fetal outcomes over the last century, there has been the recent emergence of rising rates of gestational complications including preterm birth, operative delivery, and gestational diabetes. At the same time, there has been a burgeoning problem with widespread vitamin D deficiency among populations of many developed nations. This paper provides a brief review

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2015 Obstetrics and gynecology international

153. Gestational and Early Infancy Exposure to Margarine Fortified with Vitamin D through a National Danish Programme and the Risk of Type 1 Diabetes: The D-Tect Study (PubMed)

and consisted of 331,623 individuals. The 1st of June 1985, which was the date of issue of the new ministerial order cancelling mandatory fortification of margarine with vitamin D in Denmark, served as a reference point separating the studied population into various exposure groups. We further modelled birth cohort effects in children developing T1D as a linear spline, and compared the slopes between the birth cohorts with various prenatal and infancy exposures to vitamin D fortification. In total, 886 (...) Gestational and Early Infancy Exposure to Margarine Fortified with Vitamin D through a National Danish Programme and the Risk of Type 1 Diabetes: The D-Tect Study The objective of the study was to assess whether gestational and early infancy exposure to low dose vitamin D from a mandatory margarine fortification programme in Denmark influenced the risk of developing type 1 diabetes (T1D) before age of 15 years. The study population included all individuals born in Denmark from 1983 to 1988

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2015 PloS one

154. Association between vitamin D levels and allergy-related outcomes vary by race and other factors. (PubMed)

Association between vitamin D levels and allergy-related outcomes vary by race and other factors. Allergy-related studies that include biological measurements of vitamin D preceding well-measured outcomes are needed.We sought to examine the associations between early-life vitamin D levels and the development of allergy-related outcomes in the racially diverse Wayne County Health, Environment, Allergy, and Asthma Longitudinal Study birth cohort.25-Hydroxyvitamin D (25[OH]D) levels were measured (...) in stored blood samples from pregnancy, cord blood, and age 2 years. Logistic regression models were used to calculate odds ratios (ORs) with 95% CIs for a 5 ng/mL increase in 25(OH)D levels for the following outcomes at age 2 years: eczema, skin prick tests (SPTs), increased allergen-specific IgE level (≥ 0.35 IU/mL), and doctor's diagnosis of asthma (3-6 years).Prenatal 25(OH)D levels were inversely associated with eczema (OR, 0.85; 95% CI, 0.75-0.96). The association was stronger in white children

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2015 Journal of Allergy and Clinical Immunology

155. Vitamin C supplementation ameliorates the adverse effects of nicotine on placental hemodynamics and histology in nonhuman primates. (PubMed)

Vitamin C supplementation ameliorates the adverse effects of nicotine on placental hemodynamics and histology in nonhuman primates. We previously demonstrated that prenatal nicotine exposure decreases neonatal pulmonary function in nonhuman primates, and maternal vitamin C supplementation attenuates these deleterious effects. However, the effect of nicotine on placental perfusion and development is not fully understood. This study utilizes noninvasive imaging techniques and histological (...) analysis in a nonhuman primate model to test the hypothesis that prenatal nicotine exposure adversely effects placental hemodynamics and development but is ameliorated by vitamin C.Time-mated macaques (n = 27) were divided into 4 treatment groups: control (n = 5), nicotine only (n = 4), vitamin C only (n = 9), and nicotine plus vitamin C (n = 9). Nicotine animals received 2 mg/kg per day of nicotine bitartrate (approximately 0.7 mg/kg per day free nicotine levels in pregnant human smokers) from days 26

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2015 American Journal of Obstetrics and Gynecology

156. Practice parameter update: management issues for women with epilepsy - focus on pregnancy (an evidence-based review): vitamin K, folic acid, blood levels, and breastfeeding. Report of the Quality Standards Subcommittee and Therapeutics and Technology Asse

in reporting make it difficult to establish whether the review's conclusions are reliable. Authors' objectives To assess the evidence for management issues related to the care of women with epilepsy during pregnancy, including pre-conception folic acid use, prenatal vitamin K use, risk of haemorrhagic disease of the newborn, clinical implications of placental and breast milk transfer of anti-epileptic drugs, risks of breast feeding and change in anti-epileptic drug levels during pregnancy. Searching Search (...) Practice parameter update: management issues for women with epilepsy - focus on pregnancy (an evidence-based review): vitamin K, folic acid, blood levels, and breastfeeding. Report of the Quality Standards Subcommittee and Therapeutics and Technology Asse Practice parameter update: management issues for women with epilepsy - focus on pregnancy (an evidence-based review): vitamin K, folic acid, blood levels, and breastfeeding. Report of the Quality Standards Subcommittee and Therapeutics

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2009 DARE.

157. Trial of Vitamin D Supplements to Raise Calcidiol Levels of Pregnant Women in Mongolia

Collaborators: National Center for Maternal and Child Health Research, Mongolia Zuun Kharaa Hospital Information provided by (Responsible Party): Janet Rich-Edwards, Brigham and Women's Hospital Study Details Study Description Go to Brief Summary: A double-blind randomized, placebo-controlled trial comparing the impact of 600 IU, 2000 IU, or 4000 IU of Vitamin D3 on third trimester 25(OH)D levels and change from baseline. The Vitamin D will be integrated in a standard prenatal vitamin, which will be taken (...) Vitamin D3 in prenatal vitamin Dietary Supplement: 2000 IU Vitamin D3 in prenatal vitamin Dietary Supplement: 4000 IU Vitamin D3 in prenatal vitamin Not Applicable Detailed Description: Vitamin D deficiency (serum 25(OH)D levels <20 ng/ml or 50 nmol/l) is widespread among Mongolians and is nearly universal during the winter months. The investigators have conducted a series of studies which have shown nearly universal Vitamin D deficiency in the winter months. Observational studies in the U.S. have

2015 Clinical Trials

158. Maternal Vitamin D for Acute Respiratory Infections in Infancy

of Medicine related topics: available for: Arms and Interventions Go to Arm Intervention/treatment Placebo Comparator: Group A Prenatal Period 0 IU; Postpartum Period 0 IU (placebo) Overall: The Prenatal Period will start at enrolment (17-24 weeks gestation) and last until delivery. The Postpartum Period will last from delivery until 6 months postpartum. Dietary Supplement: Placebo Experimental: Group B Prenatal Period 4,200 IU/week of vitamin D3; Postpartum Period 0 IU/week (placebo) Dietary Supplement (...) : Vitamin D3 Other Name: Cholecalciferol Experimental: Group C Prenatal Period 16,800 IU/week of vitamin D3; Postpartum Period 0 IU/week (placebo) Dietary Supplement: Vitamin D3 Other Name: Cholecalciferol Experimental: Group D Prenatal Period 28,000 IU/week of vitamin D3; Postpartum Period 0 IU/week (placebo) Dietary Supplement: Vitamin D3 Other Name: Cholecalciferol Experimental: Group E Prenatal Period 28,000 IU/week of vitamin D3; Postpartum Period 28,000 IU/week Dietary Supplement: Vitamin D3 Other

2015 Clinical Trials

159. Influence of Roux-en-Y Gastric Bypass on the Nutritional Status of Vitamin A in Pregnant Women: a Comparative Study. (PubMed)

that pregnancy after RYGB can represent a high-risk situation for VAD. We recommend interdisciplinary monitoring added to the prenatal routine consultations and the conduction of studies addressed to the investigation of a safe and effective dose of oral supplementation of vitamin A to pregnant women undergoing RYGB. (...) Influence of Roux-en-Y Gastric Bypass on the Nutritional Status of Vitamin A in Pregnant Women: a Comparative Study. The objective of the present study is to evaluate the nutritional status of vitamin A through biochemical and functional indicators of pregnant women who underwent Roux-en-Y gastric bypass (RYGB) surgery compared to pregnant women who did not undergo this surgery.The present study is a cross-sectional study of the analytical type with pregnant women paired by age and prepregnancy

2015 Obesity Surgery

160. Vitamin B-12 Status Differs among Pregnant, Lactating, and Control Women with Equivalent Nutrient Intakes. (PubMed)

, nonlactating; n = 21) women consumed vitamin B-12 amounts of ∼8.6 μg/d [mixed diet (∼6 μg/d) plus a prenatal multivitamin supplement (2.6 μg/d)]. Serum vitamin B-12, holotranscobalamin (bioactive form of vitamin B-12), methylmalonic acid (MMA), and homocysteine were measured at baseline and study-end.All participants achieved adequate vitamin B-12 status in response to the study dose. Compared with control women, pregnant women had lower serum vitamin B-12 (-21%; P = 0.02) at study-end, whereas lactating (...) Vitamin B-12 Status Differs among Pregnant, Lactating, and Control Women with Equivalent Nutrient Intakes. Limited data are available from controlled studies on biomarkers of maternal vitamin B-12 status.We sought to quantify the effects of pregnancy and lactation on the vitamin B-12 status response to a known and highly controlled vitamin B-12 intake.As part of a 10-12 wk feeding trial, pregnant (26-29 wk gestation; n = 26), lactating (5 wk postpartum; n = 28), and control (nonpregnant

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2015 Journal of Nutrition Controlled trial quality: uncertain

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