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Prenatal Vitamin

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1241. Prenatal Multi-micronutrient Supplementation and Pregnancy Outcome

Prenatal Multi-micronutrient Supplementation and Pregnancy Outcome Prenatal Multi-micronutrient Supplementation and Pregnancy Outcome - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Prenatal Multi (...) , Denmark Information provided by: Bandim Health Project Study Details Study Description Go to Brief Summary: Prenatal maternal micronutrient supplementation has been suggested as a means to reduce the proportion of low birth weight babies in low-income countries. The effects of prenatal multi-micronutrient supplements on birth weight and perinatal mortality were studied in a randomised controlled trial among 2100 pregnant women in Guinea-Bissau. Women up to 37 weeks pregnant were individually

2005 Clinical Trials

1242. Protection against Prenatal Alcohol-Induced Damage (Full text)

Protection against Prenatal Alcohol-Induced Damage 16605309 2006 06 01 2018 11 13 1549-1676 3 4 2006 Apr PLoS medicine PLoS Med. Protection against prenatal alcohol-induced damage. e196 Spong Catherine Y CY Pregnancy and Perinatology Branch, The National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, USA. spongc@mail.nih.gov eng Comment Journal Article 2006 04 18 United States PLoS Med 101231360 1549-1277 0 Central Nervous System Depressants (...) 12001-76-2 Vitamin B Complex 25X51I8RD4 Niacinamide 3K9958V90M Ethanol IM PLoS Med. 2006 Apr;3(4):e101 16478293 Adult Animals Central Nervous System Depressants toxicity Disease Models, Animal Ethanol toxicity Female Fetal Alcohol Spectrum Disorders prevention & control Humans Mice Niacinamide pharmacology Pregnancy Vitamin B Complex pharmacology 2006 4 12 9 0 2006 6 2 9 0 2006 4 12 9 0 ppublish 16605309 06-PLME-P-0141 10.1371/journal.pmed.0030196 PMC1435787 J Pharmacol Exp Ther. 2001 May;297(2):774

2006 PLoS medicine

1243. Serum osteocalcin as a marker for vitamin K-status in pregnant women and their newborn babies. (PubMed)

from mother and child. Whether the maternal HBC value may be used as a prenatal marker for estimating the fetal vitamin K-status remains to be seen. (...) Serum osteocalcin as a marker for vitamin K-status in pregnant women and their newborn babies. Osteocalcin (bone Gla-protein) is a vitamin K-dependent protein synthesized by osteoblasts. Its hydroxylapatite binding capacity (HBC) is generally used to estimate the Gla-content of circulating osteocalcin. Here we have used the HBC of serum osteocalcin as a marker for the vitamin K-status in pregnant women and their offspring. For all cases investigated the HBC values in the cord samples were

1992 Thrombosis and haemostasis Controlled trial quality: uncertain

1244. Effects of vitamin A supplementation during pregnancy and early lactation on body weight of South African HIV-infected women. (PubMed)

. Patients were randomized to receive placebo or 5,000 IU of retinyl palmitate and 30 mg of beta-carotene daily during pregnancy. At delivery, patients received placebo or 200,000 IU of retinyl palmitate. The main outcome measures were prenatal and postnatal maternal weight and weight loss at three months after delivery as measured in body mass index (BMI). Supplementation of vitamin A was not associated with improvements in prepartum weight gain but was significantly associated with improved weight (...) Effects of vitamin A supplementation during pregnancy and early lactation on body weight of South African HIV-infected women. Effects of vitamin A supplementation during pregnancy and early lactation on maternal weight among HIV-1-seropositive South African women were examined. Three hundred twelve HIV-seropositive pregnant women between 28 and 32 weeks gestation were studied as part of a randomized, double-blind, placebo-controlled trial at the King Edward VIII Hospital in Durban, South Africa

2001 Journal of health, population, and nutrition Controlled trial quality: predicted high

1245. Vitamins in early pregnancy. (Full text)

Vitamins in early pregnancy. 8688768 1996 08 29 2018 11 13 0959-8138 313 7050 1996 Jul 20 BMJ (Clinical research ed.) BMJ Vitamins in early pregnancy. 128-9 Smithells D D eng Editorial England BMJ 8900488 0959-8138 11103-57-4 Vitamin A 935E97BOY8 Folic Acid AIM IM Congenital Abnormalities etiology Female Folic Acid administration & dosage Humans Infant, Newborn Neural Tube Defects prevention & control Pregnancy Prenatal Care Vitamin A adverse effects 1996 7 20 1996 7 20 0 1 1996 7 20 0 0

1996 BMJ : British Medical Journal

1246. Use of vitamin-mineral supplements by AFDC children. (Full text)

One-A-Day vitamins, generic prenatal vitamins, and Neo-Vadrin with Iron. Data on shopping behavior and sources of products indicate that the population may not be making the best use of products or funds. Informal counseling by pharmacists at the point of sale has the potential to reduce these problems. (...) Use of vitamin-mineral supplements by AFDC children. Slightly more than 11 percent of the 1,616 children in Northern Mississippi households receiving Aid to Families with Dependent Children regularly used vitamins, according to the 540 personal interviews conducted in this study. Of the vitamins used, about 20 percent were obtained by prescription. Participation in Early and Periodic Screening, Diagnosis and Treatment (EPSDT) was found not to be related to vitamin use. The pharmacy was the main

1985 Public Health Reports

1247. Effect of vitamin D supplementation during pregnancy on foetal growth. (PubMed)

Female Humans Infant, Newborn Pregnancy Pregnancy Trimester, Third Prenatal Care Vitamin D administration & dosage 1988 12 1 1988 12 1 0 1 1988 12 1 0 0 ppublish 3243609 (...) Effect of vitamin D supplementation during pregnancy on foetal growth. 3243609 1989 05 26 2013 04 18 0971-5916 88 1988 Dec The Indian journal of medical research Indian J. Med. Res. Effect of vitamin D supplementation during pregnancy on foetal growth. 488-92 Marya R K RK Rathee S S Dua V V Sangwan K K eng Clinical Trial Journal Article Randomized Controlled Trial India Indian J Med Res 0374701 0971-5916 1406-16-2 Vitamin D IM Adult Anthropometry Birth Weight Embryonic and Fetal Development

1989 The Indian journal of medical research Controlled trial quality: uncertain

1248. Maternal antenatal administration of vitamin K1 results in increasing the activities of vitamin K-dependent coagulation factors in umbilical blood and in decreasing the incidence rate of periventricular-intraventricular hemorrhage in premature infants. (PubMed)

: (1) to determine the umbilical blood activity levels of vitamin K-dependent coagulation factors II, VII, IX and X; (2) to investigate the change in activities of these factors in premature infants' umbilical blood after prenatal administration of vitamin K1 to the mothers; and (3) to study the prophylactic effects on PIVH after maternal antenatal supplemental vitamin K1.Pregnant women in preterm labor at less than 35 weeks of gestation were randomly selected to receive antenatal vitamin K1 10 mg (...) Maternal antenatal administration of vitamin K1 results in increasing the activities of vitamin K-dependent coagulation factors in umbilical blood and in decreasing the incidence rate of periventricular-intraventricular hemorrhage in premature infants. Infants less than 35 weeks' gestation age are susceptible to periventricular-intraventricular hemorrhage (PIVH). This may be partially attributable to low concentrations of vitamin K-dependent coagulation factors. The purposes of this study were

2006 Journal of perinatal medicine Controlled trial quality: uncertain

1249. Iron in prenatal multivitamin/multimineral supplements. Bioavailability. (PubMed)

of iron absorption (in both the fasting and postprandial phases) from three of the four formulations (Stuartnatal Plus, Prenatal 1/1 and Prenate 90) provided the minimal 3.0 mg of supplemental iron per day recommended by the National Academy of Science.The observed differences in iron absorption between prenatal supplements apparently reflect the effects of the various combinations of vitamins, essential minerals and additives. The absolute amount of elemental iron contained in a prenatal multivitamin (...) Iron in prenatal multivitamin/multimineral supplements. Bioavailability. To determine the effect of the differences in the content of essential and nonessential ingredients and of a standardized meal on iron bioavailability from four popular prenatal multivitamin/multimineral supplements.Iron absorption during an eight-hour period following ingestion of a multivitamin/multimineral formulation, both fasting and postprandial, after a standardized meal, was measured in five groups of 20 pregnant

1998 Journal of Reproductive Medicine Controlled trial quality: uncertain

1250. Defined, in-home, prenatal nutrition intervention for low-income women. (PubMed)

Defined, in-home, prenatal nutrition intervention for low-income women. The purpose of this project was to develop a detailed, in-home, prenatal nutrition intervention protocol for low-income women and to assess the effectiveness of the intervention in improving their dietary intake. A secondary objective was to identify predictors of infant birth weight.A defined protocol was developed and nutritionists followed it to conduct in-home nutrition sessions that included nutrition assessment (...) the intervention revealed significant increases in total energy (2,269 to 2,431 kcal, P < .05), folate (345 to 412 micrograms, P < .01), vitamin B-6 (2.1 to 2.5 mg, P < .01), iron (17.5 to 21.2 mg, P < .01), zinc (13.6 to 14.7 mg, P < .01), and calcium (1,175 mg to 1,299 mg, P < .01) and significant (P < .01) increases in daily servings from the vegetable group (1.5 +/- 1.0 to 2.2 +/- 1.1 serving per day) and breads/grains groups (3.4 +/- 1.4 to 4.1 +/- 1.5 servings per day). There was no significant

1999 Journal of the American Dietetic Association

1251. Comparing mothers' reports on the content of prenatal care received with recommended national guidelines for care. (Full text)

Comparing mothers' reports on the content of prenatal care received with recommended national guidelines for care. The Public Health Service's Expert Panel on the Content of Prenatal Care Report in 1989 provided detailed guidelines for the components of each prenatal visit. However, the extent to which women were receiving the recommended care when the guidelines were being formulated has yet to be determined. The 1988 National Maternal and Infant Health Survey results permit an examination (...) of the proportion of women who reported receiving some of the recommended procedures. Women were asked if they received six of the recommended procedures (blood pressure measurement, urine test, blood test, weight and height taken, pelvic examination, and pregnancy history) in the first two visits, and whether they received seven types of advice or counseling (nutrition; vitamin use; smoking, alcohol, and drug use cessation; breastfeeding; and maternal weight gain) any time during their pregnancy. Only 56

1994 Public Health Reports

1252. Presumptive eligibility for pregnant Medicaid enrollees: its effects on prenatal care and perinatal outcome. (Full text)

Medicaid in the 6-month period before presumptive eligibility was enacted were compared with those obtained for pregnant women who enrolled in the 6-month period after presumptive eligibility had been in effect for 5 months.Women in the "after" group were 40% more likely to enroll and 30% more likely to obtain prenatal care in the first trimester. They were 300% more likely to fill a prescription for prenatal vitamins in the first trimester and 16% more likely to have begun prenatal care before (...) Presumptive eligibility for pregnant Medicaid enrollees: its effects on prenatal care and perinatal outcome. "Presumptive eligibility" permits pregnant prospective Medicaid enrollees to obtain services during the application period. The purpose of this study was to assess the effects of presumptive eligibility on the receipt of prenatal care and the occurrence of low-birthweight births and neonatal, perinatal, and infant mortality.Outcome rates for pregnant women who enrolled in Tennessee

1994 American Journal of Public Health

1253. Differences in preconceptional and prenatal behaviors in women with intended and unintended pregnancies. (Full text)

Differences in preconceptional and prenatal behaviors in women with intended and unintended pregnancies. This study examined whether pregnancy intention was associated with cigarette smoking, alcohol drinking, use of vitamins, and consumption of caffeinated drinks prior to pregnancy and in early pregnancy.Data from a telephone survey of 7174 pregnant women were analyzed.In comparison with women whose pregnancies were intended, women with unintended pregnancies were more likely to report (...) cigarette smoking and less likely to report daily vitamin use. Women with unintended pregnancies were also less likely to decrease consumption of caffeinated beverages or increase daily vitamin use.Pregnancy intention was associated with health behaviors, prior to pregnancy and in early pregnancy, that may influence pregnancy course and birth outcomes.

1998 American Journal of Public Health

1254. Prenatal vitamin A deficiency causes laryngeal malformation in rats. (PubMed)

Prenatal vitamin A deficiency causes laryngeal malformation in rats. Our previous research demonstrated that vitamin A might be related to vocal fold development. The purpose of this study was to determine whether vitamin A deficiency affects prenatal laryngeal development in rats.Two considerations were necessary in designing a study using a rat model: for embryonic survival, vitamin A is necessary through day 10 of gestation, and laryngeal formation occurs primarily after day 11. Thus, we (...) created a rat model that developed vitamin A deficiency after embryonic day 11. Ten pregnant rats (5 vitamin A-deficient rats and 5 control rats) were studied. Embryos were collected at embryonic day 18.5 and analyzed histologically.Eighteen percent of the vitamin A-deficient embryos were alive and demonstrated laryngotracheal cartilage malformation, incomplete separation of the glottis, and/or laryngoesophageal clefts.These results document the important role played by vitamin A in laryngeal

2007 Rhinology and Laryngology

1255. Effects of prenatal nicotine exposure on primate brain development and attempted amelioration with supplemental choline or vitamin C: neurotransmitter receptors, cell signaling and cell development biomarkers in fetal brain regions of rhesus monkeys. (Full text)

Effects of prenatal nicotine exposure on primate brain development and attempted amelioration with supplemental choline or vitamin C: neurotransmitter receptors, cell signaling and cell development biomarkers in fetal brain regions of rhesus monkeys. Studies in developing rodents indicate that nicotine is a neuroteratogen that disrupts brain development by stimulating nicotinic acetylcholine receptors (nAChRs) that control neural cell replication and differentiation. We administered nicotine (...) in combination with nicotine, choline protected some regions from damage but worsened nicotine's effects in other regions. Similarly, Vitamin C supplementation had mixed effects, increasing nAChR responses while providing protection from cell damage in the caudate, the brain region most susceptible to oxidative stress. Our results indicate that nicotine elicits neurodevelopmental damage that is highly selective for different brain regions, and that dietary supplements ordinarily thought to be neuroprotectant

2005 Neuropsychopharmacology

1256. Impact of Prenatal Vitamin/Mineral Supplements on Perinatal Mortality

Impact of Prenatal Vitamin/Mineral Supplements on Perinatal Mortality Impact of Prenatal Vitamin/Mineral Supplements on Perinatal Mortality - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Impact of Prenatal (...) Control and Prevention Study Details Study Description Go to Brief Summary: The purpose of this study is to determine whether a daily prenatal supplement of iron plus folic acid or a daily prenatal supplement with multiple vitamins and minerals given to women from their first prenatal visit through delivery reduces perinatal mortality compared with a daily prenatal supplement of folic acid alone. Condition or disease Intervention/treatment Phase Perinatal Mortality Stillbirth Neonatal Mortality

2005 Clinical Trials

1257. Vitamin C prevents the effects of prenatal nicotine on pulmonary function in newborn monkeys. (Full text)

Vitamin C prevents the effects of prenatal nicotine on pulmonary function in newborn monkeys. Smoking during pregnancy leads to decreased pulmonary function and increased respiratory illness in offspring. Our laboratory has previously demonstrated that many effects of smoking during pregnancy are mediated by nicotine. We now report that vitamin C supplementation can prevent some of the effects of maternal nicotine exposure on pulmonary function of offspring. Timed-pregnant rhesus monkeys were (...) . Neither nicotine nor nicotine plus vitamin C significantly affected levels of cortisol or cytokines, which have been shown to affect lung development and surfactant expression. Prenatal nicotine exposure significantly decreased levels of elastin content in the lungs of offspring, and these effects were slightly attenuated by vitamin C. These findings suggest that vitamin C supplementation may potentially be clinically useful to limit the deleterious effects of maternal smoking during pregnancy

2005 American Journal of Respiratory and Critical Care Medicine

1258. Prenatal vitamin K1 administration in epileptic women to prevent neonatal hemorrhage: is it effective? (PubMed)

Prenatal vitamin K1 administration in epileptic women to prevent neonatal hemorrhage: is it effective? To summarize current knowledge on whether prenatal prophylactic vitamin K1 administration to epileptic women receiving enzyme-inducing antiepileptic drugs (AEDs) to prevent neonatal hemorrhage is effective.A computerized MEDLINE search was conducted using the terms antiepileptic drug, hemorrhagic disease of the newborn, pregnancy and vitamin K since 1966 to July 2004, limited only to human (...) studies. English-language publications were selected based on their relevance to the clinical effectiveness of administration of oral vitamin K to epileptic women exposed to enzyme-inducing AEDs for prevention of hemorrhagic disease of the newborn (HDN).No randomized, controlled trial testing prenatal vitamin K1 administration for reducing the incidence or severity of neonatal hemorrhage was identified. This review summarizes the data from published observational studies.There is inadequate evidence

2006 Journal of Reproductive Medicine

1259. Prenatal vitamin C status is associated with placental apoptosis in normal-term human pregnancies. (PubMed)

Prenatal vitamin C status is associated with placental apoptosis in normal-term human pregnancies. Pregnancy is associated with increased susceptibility to oxidative stress. Deficiencies in antioxidants during pregnancy and placental oxidant-antioxidant imbalance may impair the development of the fetoplacental unit or the eventual offspring. In order to elucidate the association of prenatal status of vitamin C with the oxidative stress and apoptotic activity in normal full-term placentas, we (...) evaluated the content of placental lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) and the trophoblast apoptotic index in normal-term human pregnancies. Tissue samples of placentas obtained from 80 normal-term pregnancies were categorized into 40 cases with a lower level of prenatal vitamin C (< 8.997 microg/ml) and 40 cases with a higher level of prenatal vitamin C (> or =11.734 microg/ml). We evaluated the placental LOX-1 content and the trophoblast apoptotic index with Western blot

2007 Placenta

1260. Compliance with prenatal vitamins: Patients with morning sickness sometimes find it difficult (Full text)

Compliance with prenatal vitamins: Patients with morning sickness sometimes find it difficult Many pregnant patients cannot tolerate multivitamins because of morning sickness. Is it the tablet size or the iron content that causes the problems, and what can be done?Recent Motherisk studies have shown both tablet size and high iron content to be associated with lower compliance among women with morning sickness. It does appear that tablet size is more likely to affect compliance. Some new

2006 Canadian Family Physician

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