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Prenatal Vitamin

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81. Vitamin B12 Pregnancy Supplementation

Comparator: Receiving treatment Adding vitamin B12 at a dose of 5 μg / 100 days, custom folic acid therapy and iron supplements Dietary Supplement: vitamin b12 Vitamin B12 has been added to the experimental group of pregnant women, at a dose of 5 μg / 100 days No Intervention: Control group Standard prenatal care (custom folic acid therapy and iron supplements) Outcome Measures Go to Primary Outcome Measures : Change of Red blood cells (RBC) count in first and second trimester [ Time Frame: at two time (...) Vitamin B12 Pregnancy Supplementation Vitamin B12 Pregnancy Supplementation - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Vitamin B12 Pregnancy Supplementation The safety and scientific validity

2018 Clinical Trials

82. Position Statement: Guidelines for vitamin K prophylaxis in newborns: A joint statement of the Canadian Paediatric Society and the College of Family Physicians of Canada (Full text)

Position Statement: Guidelines for vitamin K prophylaxis in newborns: A joint statement of the Canadian Paediatric Society and the College of Family Physicians of Canada Newborns are at risk for vitamin K deficiency bleeding (VKDB) caused by inadequate prenatal storage and deficiency of vitamin K in breast milk. Systematic review of evidence to date suggests that a single intramuscular (IM) injection of vitamin K at birth effectively prevents VKDB. Current scientific data suggest that single (...) or repeated doses of oral (PO) vitamin K are less effective than IM vitamin K in preventing VKDB. The Canadian Paediatric Society and the College of Family Physicians of Canada recommend routine IM administration of a single dose of vitamin K at 0.5 mg to 1.0 mg to all newborns. Administering PO vitamin K (2.0 mg at birth, repeated at 2 to 4 and 6 to 8 weeks of age) should be confined to newborns whose parents decline IM vitamin K. Health care providers should clarify with parents that newborns

2018 Canadian Family Physician

83. Associations between maternal vitamin D levels during pregnancy and allergic outcomes in the offspring in the first 5 years of life. (Full text)

Pediatr Allergy Immunol 9106718 0905-6157 1406-16-2 Vitamin D IM Adult Child, Preschool Cohort Studies Female Humans Hypersensitivity epidemiology etiology Infant Male Pregnancy Prenatal Exposure Delayed Effects Prospective Studies Risk Factors Singapore Skin Tests Vitamin D blood Vitamin D Deficiency complications epidemiology allergic outcomes eczema family history of allergy maternal vitamin D 2019 08 01 2018 10 20 6 0 2019 3 20 6 0 2018 10 20 6 0 ppublish 30338862 10.1111/pai.12995 PMC6358006 (...) Associations between maternal vitamin D levels during pregnancy and allergic outcomes in the offspring in the first 5 years of life. 30338862 2019 03 19 2019 03 19 1399-3038 30 1 2019 02 Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology Pediatr Allergy Immunol Associations between maternal vitamin D levels during pregnancy and allergic outcomes in the offspring in the first 5 years of life. 117-122 10.1111/pai.12995 Loo Evelyn

2018 Pediatric Allergy and Immunology

84. Maternal Anthropometry and Its Relationship with the Nutritional Status of Vitamin D, Calcium, and Parathyroid Hormone in Pregnant Women After Roux-en-Y Gastric Bypass. (PubMed)

attention to the importance of monitoring the nutritional status of vitamin D3 and calcium in the prenatal period due to its relationship with pre-pregnancy BMI, TGWG, and surgical success. (...) Maternal Anthropometry and Its Relationship with the Nutritional Status of Vitamin D, Calcium, and Parathyroid Hormone in Pregnant Women After Roux-en-Y Gastric Bypass. To assess the influence of pre-pregnancy body mass index (BMI), total gestational weight gain (TGWG), and pre-pregnancy surgical success on the nutritional status of vitamin D, calcium, and parathyroid hormone (PTH) in the trimesters of pregnancy of women who previously underwent Roux-en-Y gastric bypass (RYGB

2018 Obesity Surgery

85. Vitamin B-12 content in breast milk of vegan, vegetarian, and nonvegetarian lactating women in the United States. (Full text)

the use of a B-complex vitamin and prenatal vitamin were not predictive of vitamin B-12 milk concentration (P > 0.05).Almost 20% of our study participants were classified as having low breast-milk vitamin B-12 concentrations (<310 pmol/L), independent of maternal diet pattern. Approximately 85% of participants categorized as having low vitamin B-12 were taking vitamin B-12 supplements at doses in excess of the Recommended Dietary Allowance, which suggests that more research is needed to determine (...) Vitamin B-12 content in breast milk of vegan, vegetarian, and nonvegetarian lactating women in the United States. The nutritional profile of human milk varies significantly between women, and the impact of maternal diet on these variations is not well understood.We analyzed breast-milk vitamin B-12 concentration and vitamin B-12 supplement use pattern among women who adhered to different dietary patterns: vegan, vegetarian, and nonvegetarian.A total of 74 milk samples, 29 from vegan, 19 from

2018 American Journal of Clinical Nutrition

86. Vitamin D Supplementation Attenuates Asthma Development Following Traffic-Related Particulate Matter Exposure. (Full text)

, asthma exacerbation, and/or airway inflammation and to determine the timing of vitamin D supplementation that confers maximal health benefit.Using established mouse models of asthma, we examined the effect of prenatal and postnatal vitamin D supplementation on asthma development, as well as the utility of vitamin D as a treatment for established asthma in the context of diesel exhaust particle (DEP) exposure.DEP and allergen coexposure resulted in increased airway hyperresponsiveness (AHR (...) ) and accumulation of pathogenic TH2/TH17 cells in the lungs of vitamin D-deficient mice compared with control mice. Prenatal and postnatal vitamin D supplementation significantly attenuated the development of AHR and decreased pulmonary accumulation of TH2/TH17 cells after coexposure to TRAP and allergen but not to allergen alone. Restoration of normal vitamin D status had no effect on AHR once asthma was already established.Our data establish that vitamin D confers protection against asthma development

2018 Journal of Allergy and Clinical Immunology

87. Foetal, neonatal and child vitamin D status and enamel hypomineralization. (Full text)

Foetal, neonatal and child vitamin D status and enamel hypomineralization. Recent literature suggested that higher vitamin D concentrations in childhood are associated with a lower prevalence of molar incisor hypomineralization (MIH). As tooth development already starts in utero, we aimed to study whether vitamin D status during foetal, postnatal and childhood periods is associated with the presence of hypomineralized second primary molars (HSPMs) and/or MIH at the age of six.Our study (...) : 0.84-1.07) by the age of six. Finally, we did not find higher 25(OH)D concentrations at the age of six to be associated with a significant change in the odds of having HSPM (OR 0.97, 95% CI: 0.92-1.02) or MIH (OR 1.07, 95% CI: 0.98-1.16).25(OH)D concentrations in prenatal, early postnatal and later postnatal life are not associated with the presence of HPSMs or with MIH at the age of six. Future observational research is required to replicate our findings. Furthermore, it is encouraged to focus

2018 Community Dentistry and Oral Epidemiology

88. Vitamin A Supplementation during Pregnancy Enhances Pandemic H1N1 Vaccine Response in Mothers, but Enhancement of Transplacental Antibody Transfer May Depend on When Mothers Are Vaccinated during Pregnancy. (Full text)

pregnancy and postpartum increases the breast-milk vitamin A concentration and enhances prenatal H1N1-vaccine responses in mothers, but the benefits of maternal VAS in transplacental antibody transfer may depend on the time of gestation when mothers were vaccinated. This trial was registered at clinicaltrials.gov as NCT00817661. (...) Vitamin A Supplementation during Pregnancy Enhances Pandemic H1N1 Vaccine Response in Mothers, but Enhancement of Transplacental Antibody Transfer May Depend on When Mothers Are Vaccinated during Pregnancy. In the growing embryo, the vitamin A requirement is tightly regulated. Maternal vitamin A deficiency during pregnancy may alter maternal immune function to accommodate the fetus.Our primary objective was to determine the effect of oral vitamin A supplementation (VAS) during pregnancy

2018 Journal of Nutrition Controlled trial quality: predicted high

89. Prenatal vitamin D status and risk of psychotic experiences at age 18years-a longitudinal birth cohort. (PubMed)

Prenatal vitamin D status and risk of psychotic experiences at age 18years-a longitudinal birth cohort. Low early life vitamin D status is associated with an increased risk of schizophrenia and psychotic experiences. Here we examine if maternal pregnancy vitamin D concentrations are associated with offspring psychotic experiences as young adults.A community sample of 2047 participants was investigated. Maternal prenatal 25 hydroxyvitamin D (25(OH)D) concentrations were assessed with tandem mass (...) subjects met criteria for a psychotic disorder at age 18. Based on this sample, there was no significant association between maternal 25(OH)D and psychotic disorder at 18years.Maternal vitamin D levels were not associated with risk of psychotic experiences nor psychotic disorders in this birth cohort.Copyright © 2013 Elsevier B.V. All rights reserved.

2013 Schizophrenia Research

90. Prenatal vitamin d supplementation and child respiratory health: a randomised controlled trial. (Full text)

Prenatal vitamin d supplementation and child respiratory health: a randomised controlled trial. Observational studies suggest high prenatal vitamin D intake may be associated with reduced childhood wheezing. We examined the effect of prenatal vitamin D on childhood wheezing in an interventional study.We randomised 180 pregnant women at 27 weeks gestation to either no vitamin D, 800 IU ergocalciferol daily until delivery or single oral bolus of 200,000 IU cholecalciferol, in an ethnically (...) stratified, randomised controlled trial. Supplementation improved but did not optimise vitamin D status. Researchers blind to allocation assessed offspring at 3 years. Primary outcome was any history of wheeze assessed by validated questionnaire. Secondary outcomes included atopy, respiratory infection, impulse oscillometry and exhaled nitric oxide. Primary analyses used logistic and linear regression.We evaluated 158 of 180 (88%) offspring at age 3 years for the primary outcome. Atopy was assessed

2013 PloS one Controlled trial quality: predicted high

91. Randomized placebo-controlled trial of high-dose prenatal third-trimester vitamin D3 supplementation in Bangladesh: the AViDD trial. (Full text)

Randomized placebo-controlled trial of high-dose prenatal third-trimester vitamin D3 supplementation in Bangladesh: the AViDD trial. Antenatal vitamin D status may be associated with the risk of adverse pregnancy and neonatal outcomes; however, the benefits of vitamin D supplementation during pregnancy remain unknown.We conducted a double-blind placebo-controlled randomized trial to evaluate the effect of high-dose prenatal 3rd trimester vitamin D3 supplementation on maternal and neonatal (cord (...) blood) serum 25-hydroxyvitamin D (25(OH)D) concentration (primary biochemical efficacy outcome) and maternal serum calcium concentration (primary safety measure). Eligibility criteria were pregnant women aged 18 to <35 years, at 26 to 29 weeks gestation, and residing in Dhaka, Bangladesh. 160 women were randomized by 1:1 allocation to one of two parallel intervention groups; placebo (n = 80) or 35,000 IU/week of vitamin D3 (n = 80) until delivery. All participants, study personnel and study

2013 Nutrition journal Controlled trial quality: predicted high

92. The impact of prenatal vitamin A and zinc supplementation on birth size and neonatal survival - a double-blind, randomized controlled trial in a rural area of Indonesia. (PubMed)

The impact of prenatal vitamin A and zinc supplementation on birth size and neonatal survival - a double-blind, randomized controlled trial in a rural area of Indonesia. Prenatal supplementation with micronutrients may increase birth weight and thus improve infant health and survival in settings where infants and children are at risk of micronutrient deficiencies.To assess whether vitamin A and/or zinc supplementation given during pregnancy can improve birth weight, birth length, neonatal (...) morbidity, or infant mortality.A double-blind, randomized controlled trial supplementing women (n = 2173) in Central Java, Indonesia throughout pregnancy with vitamin A, zinc, combined vitamin A+zinc, or placebo.Out of 2173 supplemented pregnant women, 1956 neonates could be evaluated. Overall, zinc supplementation improved birth length compared to placebo or combined vitamin A+zinc (48.8 vs. 48.5 cm, p = 0.04); vitamin A supplementation improved birth length compared to placebo or combined vitamin

2013 International journal for vitamin and nutrition research. Internationale Zeitschrift für Vitamin- und Ernährungsforschung. Journal international de vitaminologie et de nutrition Controlled trial quality: predicted high

93. Prenatal Vitamin

Prenatal Vitamin Prenatal Vitamin Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Prenatal Vitamin Prenatal Vitamin Aka: Prenatal (...) Vitamin II. Indications Start prior to conception of pregnancy III. Preparations: Key components (Higher doses than standard Vitamins) 400 mcg or 600 Dietary Equivalents or DFE (See for references) Dose is higher if increased risk 4000 mcg started 3 months before pregnancy (continue for first trimester) Prior Use of or 800 mcg daily (1200 Dietary Equivalents or DFE) Anti-epileptic drugs other than or Most important component in Prenatal Vitamins Reduces s by 50% at conception Reduced fetal risk

2015 FP Notebook

94. The protective role of vitamin E on the testicular tissue in rats exposed to sodium arsenite during the prenatal stage till sex maturity: A stereological analysis (Full text)

The protective role of vitamin E on the testicular tissue in rats exposed to sodium arsenite during the prenatal stage till sex maturity: A stereological analysis Vitamin E is an effective antioxidant, protecting cells against oxidative stress.In this investigation the protective effect of vitamin E on the testis during development and spermatogenesis in rats exposed to sodium arsenite was evaluated.Pregnant Wistar rats were divided into 4 groups (n=8) control, sodium arsenite (8 mg/kg/day (...) , spermatocyte, spermatid and sertoli cells reduced significantly in sodium arsenite group compared to the control. Co-administration of vitamin E and sodium arsenite compensated the adverse effects of sodium arsenite on the above parameters.We concluded co-treatment of rats with sodium arsenite and vitamin E could prevent the adverse effects of sodium arsenite exposure on the testicular tissue during the prenatal stage till sex maturity.

2012 Iranian Journal of Reproductive Medicine

95. Vitamin K in Prenatal Prevention and Postnatal Treatment of Haemorrhagic Disease of the Newborn (Full text)

Vitamin K in Prenatal Prevention and Postnatal Treatment of Haemorrhagic Disease of the Newborn 21032171 2011 03 30 2018 11 13 0003-9888 15 82 1940 Archives of disease in childhood Arch. Dis. Child. Vitamin K in Prenatal Prevention and Postnatal Treatment of Haemorrhagic Disease of the Newborn. 97-102 Kugelmass I N IN eng Journal Article England Arch Dis Child 0372434 0003-9888 2010 10 30 6 0 1940 1 1 0 0 1940 1 1 0 1 ppublish 21032171 PMC1987724 Biochem J. 1936 Jun;30(6):1075-9 16746121

1940 Archives of Disease in Childhood

96. Vitamin D levels and perinatal depressive symptoms in women at risk: a secondary analysis of the mothers, omega-3, and mental health study. (Full text)

Vitamin D levels and perinatal depressive symptoms in women at risk: a secondary analysis of the mothers, omega-3, and mental health study. Vitamin D insufficiency may be associated with depressive symptoms in non-pregnant adults. We performed this study to evaluate whether low maternal vitamin D levels are associated with depressive symptoms in pregnancy.This study was a secondary analysis of a randomized trial designed to assess whether prenatal omega-3 fatty acid supplementation would (...) prevent depressive symptoms. Pregnant women from Michigan who were at risk for depression based on Edinburgh Postnatal Depression Scale Score or history of depression were enrolled. Participants completed the Beck Depression Inventory (BDI) and Mini International Neuropsychiatric Interview at 12-20 weeks, 26-28 weeks, 34-36 weeks, and 6-8 weeks postpartum. Vitamin D levels were measured at 12-20 weeks (N = 117) and 34-36 weeks (N = 112). Complete datasets were available on 105 subjects. Using

2017 BMC pregnancy and childbirth Controlled trial quality: uncertain

97. Maternal vitamin D deficiency and the risk of autism spectrum disorders: population-based study (Full text)

with and without intellectual disability in relation to lifetime diagnoses of maternal vitamin D deficiency. Although rare, such deficiency was associated with offspring risk of ASD with, but not without, intellectual disability (aORs 2.51, 95% CI 1.22-5.16 and 1.28, 0.68-2.42). Relationships were stronger in non-immigrant children.If reflecting associations for prenatal hypovitaminosis, these findings imply gestational vitamin D substitution as a means of ASD prevention.None.© The Royal College (...) Maternal vitamin D deficiency and the risk of autism spectrum disorders: population-based study Maternal vitamin D deficiency may increase risk of autism spectrum disorder (ASD), but direct evidence is lacking.To clarify the relationship between maternal vitamin D deficiency and offspring risk of ASD with and without intellectual disability.Using a register-based total population study (N=509 639), we calculated adjusted odds ratios (aORs) and 95% confidence intervals (CIs) of ASD

2016 BJPsych open

98. Vitamin D treatment during pregnancy prevents autism-related phenotypes in a mouse model of maternal immune activation (Full text)

Vitamin D treatment during pregnancy prevents autism-related phenotypes in a mouse model of maternal immune activation Prenatal exposure to infection is a recognized environmental risk factor for neuropsychiatric disorders of developmental origins such as autism or schizophrenia. Experimental work in animals indicates that this link is mediated by maternal immune activation (MIA) involving interactions between cytokine-associated inflammatory events, oxidative stress, and other (...) that were exposed to MIA, juveniles display similar deficits in social approach behavior. Juvenile MIA offspring also show abnormal stereotyped digging and impaired acquisition and expression of tone-cued fear conditioning. Importantly, our study reveals that prenatal administration of 1,25OHD abolishes all these behavioral deficits in poly(I:C)-treated juveniles. However, prenatal administration of vitamin D had no effect on pro-inflammatory cytokine levels in dams or in fetal brains suggesting

2017 Molecular autism

99. Untangling the most probable role for vitamin D3 in autism (Full text)

Untangling the most probable role for vitamin D3 in autism Recent studies indicate an important role for vitamin D3 in autism spectrum disorder (ASD), although its mechanism is not completely understood. The most puzzling aspect of ASD is that identical twins, who share identical DNA, do not have 100% concordance rates (∼88% for identical and ∼31% for fraternal twins). These findings provide major clues into the etiology: ASD must involve an environmental factor present in the prenatal milieu (...) that both identical twins are not always exposed to because they do not always share it (i.e., placentas). Combined with the exponential increasing rates of ASD around the world, these observations suggest a contagious disease is probably transferred to the fetus via the placenta becoming infected by a cervical virus. Vitamin D3 boosts immune responses clearing viral infections and increases serotonin and estrogen brain levels. Here we review the different roles and untangle the most probable one

2017 Dermato-endocrinology

100. Relationship between the Nutritional Status of Vitamin A per Trimester of Pregnancy with Maternal Anthropometry and Anemia after Roux-en-Y Gastric Bypass (Full text)

above the recommended range showed 100% of inadequacy of this nutrient in the third trimester. Among the pregnant women with anemia, 90.9% had VAD and 86.4% had NB. This study highlights the importance of monitoring the nutritional status of vitamin A in prenatal care, due to its relationship with TGWG and the high percentage of VAD and NB found since the beginning of pregnancy. It also reaffirms the use of the cut-off <1.05 μmol/L for determining VAD. (...) Relationship between the Nutritional Status of Vitamin A per Trimester of Pregnancy with Maternal Anthropometry and Anemia after Roux-en-Y Gastric Bypass The aim of this study was to compare the nutritional status of vitamin A per trimester of pregnancy, as well as to assess its influence on pre-pregnancy BMI, total gestational weight gain (TGWG) and presence of anemia in women who had previously undergone Roux-en-Y gastric bypass (RYGB). An analytical, longitudinal and retrospective study

2017 Nutrients

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