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Prenatal Vitamin

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61. Should Men Take Prenatal Vitamins? (Full text)

Should Men Take Prenatal Vitamins? 25763298 2018 11 13 2161-038X 3 3 2014 Jul 01 Reproductive system & sexual disorders : current research Reprod Syst Sex Disord Should Men Take Prenatal Vitamins? 1000139 Scovell Jason M JM Division of Male Reproductive Medicine and Surgery, Department of Urology, Baylor College of Medicine, Houston, TX, USA. Ramasamy Ranjith R Division of Male Reproductive Medicine and Surgery, Department of Urology, Baylor College of Medicine, Houston, TX, USA. eng K12

2014 Reproductive system & sexual disorders : current research

62. The effect of an exercise program in pregnancy on vitamin D status among healthy, pregnant Norwegian women: a randomized controlled trial. (Full text)

The effect of an exercise program in pregnancy on vitamin D status among healthy, pregnant Norwegian women: a randomized controlled trial. Vitamin D insufficiency is common in pregnant women worldwide. Regular prenatal exercise is considered beneficial for maternal and fetal health. There is a knowledge gap regarding the impact of prenatal exercise on maternal vitamin D levels. The objective of this study was to investigate whether a prenatal exercise program influenced serum levels of total (...) training and two home based sessions. The controls (n = 426) received standard prenatal care, and exercising was not denied. Training diaries and group training was used to promote compliance and evaluate adherence. Serum levels of 25(OH)D, parathyroid hormone, calcium, phosphate, magnesium and vitamin D-binding protein were measured before (18-22 weeks' gestation) and after the intervention (32-36 weeks' gestation). Free and bioavailable 25(OH)D concentrations were calculated. Regression analysis

2019 BMC Pregnancy and Childbirth Controlled trial quality: predicted high

63. Particulate Air Pollution Exposure and Plasma Vitamin D Levels in Pregnant Women: A Longitudinal Cohort Study. (PubMed)

and circulating 25(OH)D levels.Our results suggest that prenatal exposure to particulate air pollution may play an independent role in maternal vitamin D deficiency. The role of air pollution should be incorporated into future guidelines for the prevention of maternal vitamin D deficiency.Copyright © 2019 Endocrine Society. (...) Particulate Air Pollution Exposure and Plasma Vitamin D Levels in Pregnant Women: A Longitudinal Cohort Study. No studies have assessed the association between air pollution exposure and vitamin D status in pregnant women.To examine the association between particulate air pollution exposure and circulating 25-hydroxyvitamin [25(OH)D] levels in pregnant women.A longitudinal cohort study.A total of 3285 pregnant women were recruited at a maternal and child health hospital.None.Serum 25(OH)D

2019 Journal of Clinical Endocrinology and Metabolism

64. Association of Maternal Vitamin D Deficiency with Early Childhood Caries. (PubMed)

Association of Maternal Vitamin D Deficiency with Early Childhood Caries. Alaska Native (AN) children experience one of the highest reported rates of severe early childhood caries (S-ECC). Serum vitamin D concentrations in AN childbearing women in the Yukon Kuskokwim Delta (YKD) region have decreased since the 1960s to currently low levels, related to a decrease in traditional marine diet. Recent studies suggest an association between prenatal vitamin D (25(OH)D) concentrations in mothers and S (...) had "sufficient" versus "insufficient" 25(OH)D during prenatal visits (9.0 vs. 7.4; P = 0.48). In this small sample, children with deficient vitamin D levels in cord blood had a dmft score at 12 to 35 mo 2-fold higher than children with nondeficient cord blood. Maternal 25(OH)D may influence the primary dentition, and improving vitamin D status in pregnant women might affect ECC rates in their infants.

2019 Journal of Dental Research

65. Vitamin D supplementation during pregnancy: state of the evidence from a systematic review of randomised trials. (Full text)

trials; systematic review of registered but unpublished trials.Data sources Medline, Embase, PubMed, Cochrane Database of Systematic Reviews, and Cochrane Central Register of Controlled Trials from inception to September 2017; manual searches of reference lists of systematic reviews identified in the electronic search; and online trial registries for unpublished, ongoing, or planned trials.Eligibility criteria for study selection Trials of prenatal vitamin D supplementation with randomised allocation (...) increased mean birth weight of 58.33 g (95% confidence interval 18.88 g to 97.78 g; 37 comparisons) and reduced the risk of small for gestational age births (risk ratio 0.60, 95% confidence interval 0.40 to 0.90; seven comparisons), but findings were not robust in sensitivity and subgroup analyses. There was no effect on preterm birth (1.0, 0.77 to 1.30; 15 comparisons). There was strong evidence that prenatal vitamin D reduced the risk of offspring wheeze by age 3 years (0.81, 0.67 to 0.98; two

2017 BMJ

66. Cord blood vitamin D status is associated with cord blood insulin and c-peptide in two cohorts of mother-newborn pairs. (PubMed)

Cord blood vitamin D status is associated with cord blood insulin and c-peptide in two cohorts of mother-newborn pairs. Vitamin D may be important for prenatal programming of insulin and glucose regulation, but maternal vitamin D deficiency during pregnancy is common.We examined associations of early vitamin D status with markers of fetal insulin secretion (cord blood insulin and c-peptide). We hypothesized that maternal 25-hydroxyvitamin D (25(OH)D) during pregnancy and cord blood 25(OH)D

2019 Journal of Clinical Endocrinology and Metabolism

67. Calcium and vitamin D supplementation and/or periodontal therapy in the treatment of periodontitis among Brazilian pregnant women: protocol of a feasibility randomised controlled trial (the IMPROVE trial). (Full text)

, adherence and attrition rate will be evaluated. Data on serum levels of vitamin D, calcium and inflammatory biomarkers; clinical periodontal measurements; anthropometric measurements; and socio-demographic questionnaires are collected at baseline, third trimester and 6-8 weeks postpartum. Qualitative data are collected using focus group, for analysis of favourable factors and barriers related to study adherence.Oral health and mineral/vitamin supplementation are much overlooked in the public prenatal (...) Calcium and vitamin D supplementation and/or periodontal therapy in the treatment of periodontitis among Brazilian pregnant women: protocol of a feasibility randomised controlled trial (the IMPROVE trial). Periodontitis is a common oral inflammation, which is a risk factor for adverse pregnancy outcomes. Intakes of vitamin D and calcium are inversely associated with occurrence and progression of periodontitis. This study aims to assess the feasibility of a multi-component intervention

2019 Pilot and feasibility studies Controlled trial quality: uncertain

68. Prophylactic Vitamin K Administration in Neonates on Prolonged Antibiotic Therapy: A Randomized Controlled Trial. (PubMed)

of antibiotic therapy (except the birth dose), cholestasis or prenatally diagnosed bleeding disorder were excluded.Randomized to receive 1 mg vitamin K (n=41) or no vitamin K (n=39) on the 7th day of antibiotic therapy.Vitamin K deficiency defined as Protein Induced by Vitamin K Absence (PIVKA-II) >2 ng/mL after 7 ± 2 days of enrolment.The prevalence of vitamin K deficiency was 100% (n=80) at enrolment and it remained 100% even after 7 ± 2 days of enrolment in both the groups.Neonates receiving prolonged (...) Prophylactic Vitamin K Administration in Neonates on Prolonged Antibiotic Therapy: A Randomized Controlled Trial. To compare the prevalence of vitamin K deficiency after intramuscular vitamin K or no treatment in neonates with sepsis on prolonged (>7 days) antibiotic therapy.Open label randomized controlled trial.Level 3 Neonatal Intensive Care Unit (NICU).Neonates with first episode of sepsis on antibiotics for ≥7 days were included. Neonates with clinical bleeding, vitamin K prior to start

2019 Indian pediatrics Controlled trial quality: uncertain

69. The Role of the 17q21 Genotype in the Prevention of Early Childhood Asthma and Recurrent Wheeze by Vitamin D. (PubMed)

The Role of the 17q21 Genotype in the Prevention of Early Childhood Asthma and Recurrent Wheeze by Vitamin D. Evidence suggests vitamin D has preventive potential for asthma, however, not all children benefit from this intervention. This study aims to investigate whether variation in the functional 17q21 SNP; rs12936231 affects the preventive potential of vitamin D against asthma.A combined secondary analysis of two randomised-controlled trials of prenatal vitamin D supplementation (...) , vitamin D and genotype (p-interactionvitaminD*genotype*age1:sphingosine-1-phosphate=0.035). In a cellular model, there was a significant difference in the induction of sphingosine-1-phosphate by vitamin D between a control Human bronchial epithelial cell-line and a cell-line overexpressing ORMDL3 (p=0.002).Results suggest prenatal vitamin D supplementation may reduce risk of early childhood asthma/wheeze via alterations of sphingolipid metabolism dependent on 17q21 genotype.clinicaltrials.gov

2019 European Respiratory Journal

70. Prenatal Lipid-Based Nutrient Supplements Affect Maternal Anthropometric Indicators Only in Certain Subgroups of Rural Bangladeshi Women. (Full text)

Prenatal Lipid-Based Nutrient Supplements Affect Maternal Anthropometric Indicators Only in Certain Subgroups of Rural Bangladeshi Women. Maternal undernutrition and low macro- and micronutrient intake and weight gain during pregnancy have been reported in Bangladesh.We aimed to determine the effects of lipid-based nutrient supplements for pregnant and lactating women (LNS-PL) on weight gain and midupper arm circumference (MUAC) during pregnancy.The Rang-Din Nutrition Study, a cluster (...) -randomized effectiveness trial conducted in Bangladesh, enrolled 4011 pregnant women at ≤20 wk gestation who received either 60 mg Fe + 400 μg folic acid/d or 20 g LNS-PL/d (118 kcal) containing essential fatty acids and vitamins and minerals until delivery. At 36 wk gestation, women were interviewed at home and then attended a follow-up examination at local clinics (n = 2877), where anthropometric measurements were taken.No significant differences between intervention groups in maternal weight gain per

2017 The Journal of nutrition Controlled trial quality: uncertain

71. Is Nutrient Content and Other Label Information for Prescription Prenatal Supplements Different from Nonprescription Products? (Full text)

in the United States regarding declared nutrient and nonnutrient ingredients and the presence of dosing and safety-related information.Using two publicly available databases with information about prenatal supplement products, information from prescription and nonprescription product labels were extracted and evaluated. For the 82 prescription and 132 nonprescription products, declared label amounts of seven vitamins and minerals, docosahexaenoic acid (DHA), the presence of other nonnutrient components (...) Is Nutrient Content and Other Label Information for Prescription Prenatal Supplements Different from Nonprescription Products? Prenatal supplements are often recommended to pregnant women to help meet their nutrient needs. Many products are available, making it difficult to choose a suitable supplement because little is known about their labeling and contents to evaluate their appropriateness.To determine differences between prescription and nonprescription prenatal supplements available

2017 Journal of the Academy of Nutrition and Dietetics

72. Prenatal Exposures and the Development of Childhood Wheezing Illnesses (Full text)

suggests an adverse impact of maternal obesity during pregnancy and prenatal exposure to antibiotics on these outcomes. There is insufficient evidence to support an association between in-utero exposure to acetaminophen or prenatal levels of specific nutrients (such as vitamin D, folic acid, or polyunsaturated fatty acids) and childhood wheezing illnesses.Several common potentially modifiable prenatal exposures appear to be consistently associated with childhood wheezing illnesses (e.g. parental (...) Prenatal Exposures and the Development of Childhood Wheezing Illnesses To critically evaluate and summarize studies published between July 2015 and June 2016 linking prenatal exposures and the onset of childhood wheezing illnesses and to discuss future research directions in this field.The aggregated evidence indicates a consistent detrimental effect of prenatal exposure to parental smoking, outdoor air pollution, and maternal stress on childhood wheezing illnesses. Less consistent evidence

2017 Current Opinion in Allergy and Clinical Immunology

73. Associations among Prenatal Stress, Maternal Antioxidant Intakes in Pregnancy, and Child Temperament at Age 30 Months (Full text)

events and child temperament, and effect modification by maternal prenatal antioxidant intakes (vitamins A, C, and E, magnesium, zinc, selenium, β-carotene). Analyses revealed that increased maternal prenatal negative life events were associated with higher child Negative Affectivity (β=0.08, P=0.009) but not with child Effortful Control (β=-0.03, P=0.39) or Surgency/Extraversion (β=0.04, P=0.14). Prenatal intakes of zinc and selenium modified this effect: Maternal exposure to prenatal negative life (...) events was associated with higher child Negative Affectivity in the presence of lower intakes of zinc and selenium. Modification effects approached significance for vitamins A and C. The results suggest that the combination of elevated stress exposures and lower antioxidant intakes in pregnancy increases the likelihood of heightened child temperamental negative affectivity. Increased antioxidant intakes during pregnancy may protect against influences of prenatal stress on child temperament.

2017 Journal of developmental origins of health and disease

74. Prenatal Lipid-Based Nutrient Supplements Do Not Affect Pregnancy or Childbirth Complications or Cesarean Delivery in Bangladesh: A Cluster-Randomized Controlled Effectiveness Trial. (PubMed)

Prenatal Lipid-Based Nutrient Supplements Do Not Affect Pregnancy or Childbirth Complications or Cesarean Delivery in Bangladesh: A Cluster-Randomized Controlled Effectiveness Trial. Background: Pregnancy and childbirth complications and cesarean delivery are common in Bangladesh.Objective: We evaluated the effect of lipid-based nutrient supplements for pregnant and lactating women (LNS-PL) on pregnancy and childbirth complications and cesarean delivery.Methods: We conducted the Rang-Din (...) Nutrition Study, a cluster-randomized controlled effectiveness trial within a community health program in rural Bangladesh. We enrolled 4011 pregnant women in early pregnancy. Women in 48 clusters received iron and folic acid (IFA; 60 mg Fe + 400 μg folic acid/d) and women in 16 clusters received LNS-PL (20 g/d, 118 kcal) containing essential fatty acids and 22 vitamins and minerals. Pregnancy and childbirth complications and the cesarean delivery rate were secondary outcomes of the study.Results: Women

2017 Journal of Nutrition Controlled trial quality: uncertain

75. Prenatal and Early Life Triclosan and Parabens Exposure and Allergic Outcomes. (Full text)

Prenatal and Early Life Triclosan and Parabens Exposure and Allergic Outcomes. In cross-sectional studies triclosan and parabens, ubiquitous ingredients in personal care and other products, are associated with allergic disease.We investigated the association between prenatal and early-life triclosan and paraben exposure and childhood allergic disease in a prospective longitudinal study.Subjects were enrollees in the Vitamin D Antenatal Asthma Reduction Trial. Triclosan, methyl paraben (...) between prenatal and early-life triclosan or paraben concentrations and childhood asthma, recurrent wheeze, or allergic sensitization in the overall study population. The differential effects of triclosan or paraben exposure on allergic sensitization by sex observed in this study warrant further exploration.Copyright © 2017 American Academy of Allergy, Asthma & Immunology. All rights reserved.

2017 Journal of Allergy and Clinical Immunology

76. Vitamin D supplementation: Recommendations for Canadian mothers and infants

for their supply of vitamin D, which crosses the placenta and is reflected both in infant stores and in the amount of vitamin D available in breast milk. It is important that mothers have levels of vitamin D sufficient to meet their own needs and those of their infants. How much maternal supplementation is sufficient? Health Canada has suggested 200 IU/day (5 µg/day) . The existing prenatal supplements contain 400 IU of vitamin D3 per suggested daily dose. Subscripts refer to the type of vitamin D used – D 3 (...) Vitamin D supplementation: Recommendations for Canadian mothers and infants Vitamin D supplementation: Recommendations for Canadian mothers and infants | Canadian Paediatric Society CPS In this section Protecting and promoting the health and well-being of children and youth CPS Policy & Advocacy Clinical Practice Education & Events News & Publications Programs Membership About the CPS Position statement Vitamin D supplementation: Recommendations for Canadian mothers and infants Posted: Oct 1

2012 Canadian Paediatric Society

77. Effects of Maternal Vitamin D Supplementation on the Maternal and Infant Epigenome. (Full text)

and lactation alters DNA methylation in mothers and breastfed infants. Additional work is needed to fully elucidate the short- and long-term biologic effects of vitamin D supplementation at varying doses, which could hold important implications for establishing clinical recommendations for prenatal and offspring health promotion. (...) Effects of Maternal Vitamin D Supplementation on the Maternal and Infant Epigenome. Mothers and infants are at high risk for inadequate vitamin D status. Mechanisms by which vitamin D may affect maternal and infant DNA methylation are poorly understood.This study quantified the effects of vitamin D3 supplementation on DNA methylation in pregnant and lactating women and their breastfed infants.In this randomized controlled pilot study, pregnant women received vitamin D3 400 international units

2018 Breastfeeding medicine : the official journal of the Academy of Breastfeeding Medicine Controlled trial quality: uncertain

78. Acetaminophen, antibiotics, ear infection, breastfeeding, vitamin D drops, and autism: an epidemiological study (Full text)

Acetaminophen, antibiotics, ear infection, breastfeeding, vitamin D drops, and autism: an epidemiological study While many studies have examined environmental risk factors for autism spectrum disorder (ASD), much of the research focus has been on prenatal or perinatal factors. Yet, the postnatal environment may affect the risk of ASD as well.To determine whether a set of five postnatal variables are associated with ASD. These variables are: acetaminophen exposure, antibiotic exposure, incidence (...) of ear infection, decreased duration of breastfeeding, and decreased consumption of oral vitamin D drops.An Internet-based survey was conducted. Participants were parents living in the USA with at least one biological child between 3 and 12 years of age. Potential participants were informed about the survey via postings on social media, websites, and listservs and were offered an opportunity to participate in a raffle as well. Participants were also recruited through the Interactive Autism

2018 Neuropsychiatric disease and treatment

79. Vitamins A and E during Pregnancy and Allergy Symptoms in an Early Childhood—Lack of Association with Tobacco Smoke Exposure (Full text)

children who were prenatally exposed or not exposed to tobacco smoke. The study participants included 252 mother-child pairs from Polish Mother and Child Cohort. Vitamin concentrations were measured using the HPLC-UV method, smoking status—as saliva cotinine level using the HPLC-MS/MS technique. Children’s health status was assessed using a questionnaire and pediatricians/allergists examination. Cord plasma vitamin concentrations were significantly lower than their levels in maternal plasma (...) Vitamins A and E during Pregnancy and Allergy Symptoms in an Early Childhood—Lack of Association with Tobacco Smoke Exposure Epidemiological studies have suggested an association between maternal antioxidant levels during pregnancy and development of allergic diseases in their offspring. The aim of the study was to determine plasma vitamins A and E concentration in the 1st trimester of pregnancy, at delivery and in cord blood and to search for a relationship with allergy in up to 2-year-old

2018 International journal of environmental research and public health

80. In utero exposure to extra vitamin D from food fortification and the risk of subsequent development of gestational diabetes: the D-tect study (Full text)

-ecological study is based on the cancellation in 1985 of the mandatory policy to fortify margarine with vitamin D in Denmark, with inclusion of entire national adjacent birth cohorts either exposed or unexposed to extra vitamin D in utero. The identification of GDM cases later in life among both exposure groups was based on the Danish national health registers. Logistic regression analyses generating odds ratios (ORs) and 95% confidence intervals (95% CIs) were performed.Women who were prenatally exposed (...) to the extra vitamin D from fortification tended to have a lower risk of subsequently developing GDM than unexposed women (OR 0.87, 95%CI 0.74,1.02, P = 0.08). When analyses were stratified by women's season of birth, exposed women born in spring had a lower risk of developing GDM compared to unexposed subjects (OR 0.68, 95%CI 0.50,0.94, p = 0.02).This study suggests that prenatal exposure to extra vitamin D from mandatory fortification may lower the risk of developing gestational diabetes among spring

2018 Nutrition journal

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