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Premature Rupture of Membranes

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61. Correction to: Pourali et al., Induction of labour in term premature rupture of membranes; oxytocin versus sublingual misoprostol; a randomised clinical trial. (Full text)

Correction to: Pourali et al., Induction of labour in term premature rupture of membranes; oxytocin versus sublingual misoprostol; a randomised clinical trial. 30999797 2019 11 20 1364-6893 39 5 2019 Jul Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology J Obstet Gynaecol Correction to: Pourali et al., Induction of labour in term premature rupture of membranes; oxytocin versus sublingual misoprostol; a randomised clinical trial. 735 10.1080

2019 Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology Controlled trial quality: uncertain PubMed abstract

62. The utility of ultrasound assessment in the management of preterm prelabor rupture of the membranes. (Abstract)

The utility of ultrasound assessment in the management of preterm prelabor rupture of the membranes. To evaluate the utility of ultrasound markers in the management of pregnancies complicated with PPROM between 230/7 and 336/7 weeks of gestation, and to assess their predictability of adverse neonatal outcomes.A retrospective cohort study of all patients with PPROM between 230/7 and 336/7 weeks of gestation and latency period > 24 hours, who were admitted to a tertiary referral center between

2019 Ultrasound in Obstetrics and Gynecology

63. Association between periodontal disease and preterm prelabor rupture of membranes. (Abstract)

Association between periodontal disease and preterm prelabor rupture of membranes. Periodontal disease is a possible contributing factor to preterm delivery. The aim of this study was to compare the periodontal status of women with preterm prelabour rupture of membranes (PPROM) and women with uncomplicated singleton pregnancies.Seventy-eight women with PPROM at gestational ages between 24 + 0 and 36 + 6 weeks and 77 healthy women with uncomplicated pregnancies, matched for gestational age (...) at sampling without preterm birth, were included in this study. All women underwent evaluation of periodontal and oral hygiene status.Women with PPROM had higher gingival and plaque indexes in crude analysis (gingival index: median 0.80 versus 0.20; p < 0.0001; plaque index: median 0.80 versus 0.10; p < 0.0001), even after adjustment for smoking status (p < 0.0001 and p < 0.0001). Mean clinical attachment loss (CAL) and probing pocket depth (PPD) values were higher in women with PPROM in the crude

2019 Journal of Clinical Periodontology

64. A randomized trial of Foley Bulb for Labor Induction in Premature Rupture of Membranes in Nulliparas (FLIP) (Abstract)

A randomized trial of Foley Bulb for Labor Induction in Premature Rupture of Membranes in Nulliparas (FLIP) In premature rupture of membranes (PROM), the risk of chorioamnionitis increases with increasing duration of membrane rupture. Decreasing the time from PROM to delivery is associated with lower rates of maternal infection. The American College of Obstetricians and Gynecologists suggests that all women with PROM who do not have a contraindication to vaginal delivery have their labor

2017 EvidenceUpdates

65. Impact of Latency Duration on the Prognosis of Preterm Infants after Preterm Premature Rupture of Membranes at 24 to 32 Weeks' Gestation: A National Population-Based Cohort Study. (Full text)

Impact of Latency Duration on the Prognosis of Preterm Infants after Preterm Premature Rupture of Membranes at 24 to 32 Weeks' Gestation: A National Population-Based Cohort Study. To assess the impact of latency duration on survival, survival without severe morbidity, and early-onset sepsis in infants born after preterm premature rupture of membranes (PPROM) at 24-32 weeks' gestation.This study was based on the prospective national population-based Etude Épidémiologique sur les Petits Ȃges (...) Gestationnels 2 cohort of preterm births and included 702 singletons delivered in France after PPROM at 24-32 weeks' gestation. Latency duration was defined as the time from spontaneous rupture of membranes to delivery, divided into 4 periods (12 hours to 2 days [reference], 3-7 days, 8-14 days, and >14 days). Multivariable logistic regression was used to assess the relationship between latency duration and survival, survival without severe morbidity at discharge, or early-onset sepsis.Latency duration

2017 Journal of Pediatrics PubMed abstract

66. Randomised controlled trial: Early planned birth may reduce neonatal sepsis compared to expectant management following preterm premature rupture of the membranes close to term

Randomised controlled trial: Early planned birth may reduce neonatal sepsis compared to expectant management following preterm premature rupture of the membranes close to term Early planned birth may reduce neonatal sepsis compared to expectant management following preterm premature rupture of the membranes close to term | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser (...) to expectant management following preterm premature rupture of the membranes close to term Article Text Therapeutics Randomised controlled trial Early planned birth may reduce neonatal sepsis compared to expectant management following preterm premature rupture of the membranes close to term Jonathan Morris Statistics from Altmetric.com Commentary on: van der Ham DP , Vijgen SM , Nijhuis JG , et al .; on behalf of the PPROMEXIL trial group . Induction of labor versus expectant management in women

2013 Evidence-Based Medicine

67. Correction: Systemic and Local Inflammatory Response in Women with Preterm Prelabor Rupture of Membranes. (Full text)

Correction: Systemic and Local Inflammatory Response in Women with Preterm Prelabor Rupture of Membranes. [This corrects the article DOI: 10.1371/journal.pone.0085277.].

2017 PLoS ONE PubMed abstract

68. Prolonged latency of preterm prelabour rupture of membranes and neurodevelopmental outcomes: a secondary analysis. (Full text)

Prolonged latency of preterm prelabour rupture of membranes and neurodevelopmental outcomes: a secondary analysis. To determine whether prolonged latency after preterm prelabour rupture of membranes (PPROM) is associated with an increased risk for adverse neurodevelopmental outcomes.This is a secondary analysis of the randomised controlled trial of magnesium sulphate for the prevention of cerebral palsy.Multicentre trial.A total of 1305 women with PPROM were analysed, 1056 of whom had

2018 BJOG : an international journal of obstetrics and gynaecology Controlled trial quality: predicted high PubMed abstract

69. Risk factors of premature rupture of membranes in public hospitals at Mekele city, Tigray, a case control study. (Full text)

Risk factors of premature rupture of membranes in public hospitals at Mekele city, Tigray, a case control study. The incidence of premature rupture of membranes ranges from about 5% to 10% of all deliveries. A woman with premature rupture of membranes is at risk of intra-amniotic infection, postpartum infection, endometritis, and death. A neonate born from premature rupture of membranes mother is at high risk of respiratory distress syndrome, sepsis, intraventricular hemorrhage and death (...) . Little is known regarding the risk factors in Ethiopia. Therefore, this study was conducted to identify risk factors of premature rupture of membranes among pregnant women admitted to public hospitals in Mekelle city, Tigray, Ethiopia.Hospital based unmatched case control study design was implemented on 240 samples (160 controls and 80 cases) from pregnant mothers admitted to public hospitals in Mekelle city from February - April/2016. Data was collected by interviewer administered Structured

2018 BMC Pregnancy and Childbirth PubMed abstract

70. Premature Rupture of Membranes at 34 to 37 Weeks' Gestation

a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Layout table for eligibility information Ages Eligible for Study: Child, Adult, Older Adult Sexes Eligible for Study: Female Accepts Healthy Volunteers: No Criteria Inclusion Criteria: Preterm premature rupture of membranes. Singleton gestation. Pregnant between 34 weeks 0 days to 36 weeks 6 days. Exclusion Criteria: Non cephalic presentation (...) Premature Rupture of Membranes at 34 to 37 Weeks' Gestation Premature Rupture of Membranes at 34 to 37 Weeks' Gestation - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Premature Rupture of Membranes at 34

2018 Clinical Trials

71. Amniotic fluid cell-free DNA in preterm prelabor rupture of membranes. (Abstract)

Amniotic fluid cell-free DNA in preterm prelabor rupture of membranes. We evaluated the levels of cell-free nuclear DNA (nDNA) and cell-free mitochondrial DNA (mtDNA) in the amniotic fluid supernatant from pregnancies complicated by preterm prelabor rupture of membranes (PPROM) based on evidence of microbial invasion of the amniotic cavity (MIAC) and/or intra-amniotic inflammation (IAI).A total of 155 women with PPROM were included in this study. Amniotic fluid samples were obtained

2018 Prenatal diagnosis

72. A Novel Approach to Serial Amnioinfusion in a Case of Premature Rupture of Membranes Near the Limit of Viability (Full text)

A Novel Approach to Serial Amnioinfusion in a Case of Premature Rupture of Membranes Near the Limit of Viability Prelabor rupture of the membranes (PROM) near the limit of viability is associated with significant risks for both mother and fetus. Preterm labor, intra-amniotic infection, and placental abruption are the immediate risks to the pregnancy; however, the fetus incurs additional risks related to the sequela of persistent oligohydramnios. Transabdominal intra-amniotic infusions have been (...) resulted in membrane resealing and neonatal survival with no additional maternal morbidity.

2018 AJP Reports PubMed abstract

73. Risk Factors for Neonatal Sepsis in Pregnant Women with Premature Rupture of the Membrane (Full text)

Risk Factors for Neonatal Sepsis in Pregnant Women with Premature Rupture of the Membrane Premature rupture of the membrane (PROM) is associated with high maternal as well as perinatal morbidity and mortality risks. It occurs in 5 to 10% of all pregnancy while incidence of amniotic membrane infection varies from 6 to 10%. This study aimed to determine the incidence of neonatal sepsis in Cipto Mangunkusumo Hospital and the risk factors.A cross-sectional study was done in Cipto Mangunkusumo (...) . The analysis showed that risk of neonatal sepsis was higher in pregnant women with prolonged rupture of membrane for ≥ 18 hours before hospital admission (OR 3.08), prolonged rupture of membrane for ≥ 15 hours during hospitalization (OR 7.32), and prolonged rupture of membrane for ≥ 48 hours until birth (OR 5.77). The risk of neonatal sepsis was higher in preterm pregnancy with gestational age of <37 weeks (OR 18.59).Risk of neonatal sepsis is higher in longer duration of prolonged rupture of membrane

2018 Journal of pregnancy PubMed abstract

74. Correction: Systemic and Local Inflammatory Response in Women with Preterm Prelabor Rupture of Membranes. (Full text)

Correction: Systemic and Local Inflammatory Response in Women with Preterm Prelabor Rupture of Membranes. [This corrects the article DOI: 10.1371/journal.pone.0085277.].

2017 PLoS ONE PubMed abstract

75. Maternal serum C-reactive protein concentration and intra-amniotic inflammation in women with preterm prelabor rupture of membranes. (Full text)

Maternal serum C-reactive protein concentration and intra-amniotic inflammation in women with preterm prelabor rupture of membranes. To evaluate maternal serum C-reactive protein (CRP) concentrations in pregnancies complicated by preterm prelabor rupture of membranes (PPROM) in relation to the presence of microbial invasion of the amniotic cavity (MIAC) and/or intra-amniotic inflammation (IAI).Two hundred and eighty-seven women with singleton pregnancies complicated by PPROM between 2014

2017 PLoS ONE PubMed abstract

76. Maternal white blood cell count cannot identify the presence of microbial invasion of the amniotic cavity or intra-amniotic inflammation in women with preterm prelabor rupture of membranes. (Full text)

Maternal white blood cell count cannot identify the presence of microbial invasion of the amniotic cavity or intra-amniotic inflammation in women with preterm prelabor rupture of membranes. The main aim of this study was to determine the relationship between the maternal white blood cell (WBC) count at the time of hospital admission in pregnancies complicated by preterm prelabor rupture of membranes (PPROM) and the presence of microbial invasion of the amniotic cavity (MIAC) and/or intra

2017 PLoS ONE PubMed abstract

77. Maternal lead exposure and premature rupture of membranes: a birth cohort study in China. (Full text)

Maternal lead exposure and premature rupture of membranes: a birth cohort study in China. Maternal exposure to lead (Pb) has been suggested to correlate with adverse birth outcomes, but evidence supporting an association between Pb exposure and premature rupture of membranes (PROM) is limited. The aim of our study was to investigate whether maternal Pb exposure was associated with PROM and preterm PROM.Cross-sectional cohort study.The present study involved 7290 pregnant women from the Healthy (...) Baby Cohort in Wuhan, China, during 2012-2014.PROM was defined as spontaneous rupture of amniotic membranes before the onset of labour and was determined with a pH ≥6.5 for vaginal fluid. Maternal urinary Pb level was adjusted by creatinine concentration, and its relationship with PROM was analysed by logistic regression.The IQR of maternal urinary Pb concentrations of the study population was 2.30-5.64 µg/g creatinine with a median of 3.44 µg/g creatinine. Increased risk of PROM was significantly

2018 BMJ open PubMed abstract

78. Vaginal dysbiosis increases risk of preterm fetal membrane rupture, neonatal sepsis and is exacerbated by erythromycin. (Full text)

Vaginal dysbiosis increases risk of preterm fetal membrane rupture, neonatal sepsis and is exacerbated by erythromycin. Preterm prelabour rupture of the fetal membranes (PPROM) precedes 30% of preterm births and is a risk factor for early onset neonatal sepsis. As PPROM is strongly associated with ascending vaginal infection, prophylactic antibiotics are widely used. The evolution of vaginal microbiota compositions associated with PPROM and the impact of antibiotics on bacterial compositions (...) are unknown.We prospectively assessed vaginal microbiota prior to and following PPROM using MiSeq-based sequencing of 16S rRNA gene amplicons and examined the impact of erythromycin prophylaxis on bacterial load and community structures.In contrast to pregnancies delivering at term, vaginal dysbiosis characterised by Lactobacillus spp. depletion was present prior to the rupture of fetal membranes in approximately a third of cases (0% vs. 27%, P = 0.026) and persisted following membrane rupture (31%, P

2018 BMC Medicine PubMed abstract

79. A Randomized Trial of Induction Methods in Premature Rupture of Membranes

prostaglandin E2, while the other half will be used alone vaginal prostaglandin E2. Condition or disease Intervention/treatment Phase Preterm Premature Rupture of Fetal Membranes Induction of Labor Affected Fetus / Newborn Device: Foley balloon catheter Not Applicable Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial) Estimated Enrollment : 200 participants Allocation: Randomized Intervention Model: Parallel Assignment Masking: None (Open Label) Primary (...) A Randomized Trial of Induction Methods in Premature Rupture of Membranes A Randomized Trial of Induction Methods in Premature Rupture of Membranes - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more

2018 Clinical Trials

80. Use of Placental Alpha Microglobulin-1(PAMG-1) to Diagnose Premature Rupture of Membranes in Pregnant Women

Intervention/treatment Phase Preterm Labor Preterm Birth Device: PAMG-1 immunoassay Not Applicable Detailed Description: The study is to evaluate the accuracy of the PAMG-1 immunoassay in comparison to standard diagnostic methods for premature preterm rupture of membranes including the sterile speculum exam and the amniodye test as the gold standard. The procedure includes the insertion of a swab into the subject's vaginal vault without a speculum for one minute. Once the swab is obtained, the treating (...) : Interventional (Clinical Trial) Actual Enrollment : 162 participants Allocation: Non-Randomized Intervention Model: Parallel Assignment Masking: None (Open Label) Primary Purpose: Diagnostic Official Title: A Comparison of the Measurement of Placental Alpha-microglobulin-1 in Cervicovaginal Discharge, Sterile Speculum Exam, and Amniodye Testing for the Diagnosis of Preterm Premature Rupture of Membranes Actual Study Start Date : September 2007 Actual Primary Completion Date : July 2011 Actual Study

2018 Clinical Trials

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