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Potassium Replacement

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141. Substitution of Redox Chemicals for Radiation in Phytochrome-Mediated Photomorphogenesis1 Full Text available with Trip Pro

Substitution of Redox Chemicals for Radiation in Phytochrome-Mediated Photomorphogenesis1 The reducing agents, potassium ferrocyanide, beta-mercaptoethylamine, cysteine, reduced DPN, ferrous sulfate, methyl viologen and ascorbic acid caused the expansion in darkness of disks of primary leaf tissue cut from dark-grown bean plants. The reducing agents interacted synergistically with low irradiances of red radiation and additively with high irradiance of red light. Exposure of disks treated (...) with reducing agents to far red light repressed disk expansion and the decay in sensitivity to far red radiation showed the same time relations as sequential exposure to red and far red radiation.The oxidizing agents, 1,4-naphthoquinone, ferric sulfate, hydrogen peroxide, t-butyl hydroperoxide, cystine, and potassium ferricyanide repressed the expansion of leaf disks initiated by exposure to red radiation. The oxidizing agents interacted synergistically with low irradiances of far red light and additively

1966 Plant physiology

142. Substitute for agar in solid media for common usages in microbiology. Full Text available with Trip Pro

Substitute for agar in solid media for common usages in microbiology. The potassium salt of carrageenan was found to be an adequate replacement for agar in solid bacteriological media. The common microbial genetic techniques, such as purifying colonies by streaking, replication tests, and titration of cultures, were carried out sucessfully with a number of mutant strains of Escherichia coli.

1976 Applied and environmental microbiology

143. Blocking of valinomycin-mediated bilayer membrane conductance by substituted benzimidazoles. Full Text available with Trip Pro

Blocking of valinomycin-mediated bilayer membrane conductance by substituted benzimidazoles. Valinomycin selectively transports alkali cations, e.g. potassium ions, across lipid bilayer membranes. The blocking of this carrier-mediated transport by four substituted benzimidazoles has been investigated. The compounds are 4,5,6,7-tetrachloro-2-trifluoromethylbenzimidazole, (TTFB); 4,5,6,7,-tetrachloro-2-methylbenzimidazole, (TMB); 2-trifluoromethylbenzimidazole, (TFB); and 2-methylbenzimidazole

1976 Biophysical journal

144. When salt substitutes are required in low-sodium diets. Full Text available with Trip Pro

When salt substitutes are required in low-sodium diets. 359821 1978 12 20 2018 11 13 0027-9684 70 4 1978 Apr Journal of the National Medical Association J Natl Med Assoc When salt substitutes are required in low-sodium diets. 255-8 Lakhanpal R K RK eng Historical Article Journal Article United States J Natl Med Assoc 7503090 0027-9684 0 Food Additives 451W47IQ8X Sodium Chloride 660YQ98I10 Potassium Chloride IM Q Diet, Sodium-Restricted adverse effects history Food Additives History, 19th (...) Century History, 20th Century History, Ancient Humans Hypertension diet therapy Potassium Chloride administration & dosage Sodium Chloride adverse effects 1978 4 1 1978 4 1 0 1 1978 4 1 0 0 ppublish 359821 PMC2609635 J Am Diet Assoc. 1954 Nov;30(11):1146-8 13211181 AMA Arch Intern Med. 1954 Oct;94(4):525-31 13196737 Pediatrics. 1953 May;11(5):554-67 13055370 Am J Cardiol. 1961 Nov;8:737-40 13894852 Am J Cardiol. 1976 Nov 23;38(6):768-85 793367 N Engl J Med. 1975 Feb 6;292(6):320 1110717 J Am Diet

1978 Journal of the National Medical Association

145. BIOELECTRIC POTENTIALS IN VALONIA : THE EFFECT OF SUBSTITUTING KCl FOR NaCl IN ARTIFICIAL SEA WATER Full Text available with Trip Pro

BIOELECTRIC POTENTIALS IN VALONIA : THE EFFECT OF SUBSTITUTING KCl FOR NaCl IN ARTIFICIAL SEA WATER The P.D. across the protoplasm of Valonia macrophysa has been studied while the cells were exposed to artificial solutions resembling sea water in which the concentration of KCl was varied from 0 to 0.500 mol per liter. The P.D. across the protoplasm is decreased by lowering and increased by raising the concentration of KCl in the external solution. Changes in P.D. with time when the cell (...) .-time curve have been interpreted as indicating that potassium enters Valonia protoplasm more rapidly from alkaline than from acidified KCl-rich sea water. This conclusion is discussed in relation to certain theories which have been proposed to explain the accumulation of KCl in Valonia sap. The initial rise in P.D. when a Valonia cell is transferred from natural sea water to KCl-rich sea water has been correlated with the concentrations of KCl in the sea waters. It is assumed that the observed P.D

1932 The Journal of general physiology

146. The Impact of Neut During KCL Replacement on Pain and Incidence of Phlebitis

The Impact of Neut During KCL Replacement on Pain and Incidence of Phlebitis The Impact of Neut During Potassium Chloride Replacement on Pain and Incidence of Phlebitis - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before (...) adding more. The Impact of Neut During Potassium Chloride Replacement on Pain and Incidence of Phlebitis (Neut-WKBH) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT02082717 Recruitment Status : Enrolling by invitation First Posted : March 10, 2014 Last Update Posted : February 5, 2018 Sponsor

2014 Clinical Trials

147. Effect of Perioperative Glucocorticoid Replacement on Prognosis of Surgical Patients With Sellar Lesions

Effect of Perioperative Glucocorticoid Replacement on Prognosis of Surgical Patients With Sellar Lesions Effect of Perioperative Glucocorticoid Replacement on Prognosis of Surgical Patients With Sellar Lesions - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100 (...) ). Please remove one or more studies before adding more. Effect of Perioperative Glucocorticoid Replacement on Prognosis of Surgical Patients With Sellar Lesions The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT02190994 Recruitment Status : Unknown Verified July 2014 by Shu Jiang, West China Hospital

2014 Clinical Trials

148. Determinants of frequency-dependent regulation of Kv1.2-containing potassium channels Full Text available with Trip Pro

Determinants of frequency-dependent regulation of Kv1.2-containing potassium channels Voltage-gated potassium channels are important regulators of electrical excitation in many tissues, with Kv1.2 standing out as an essential contributor in the CNS. Genetic deletion of Kv1.2 invariably leads to early lethality in mice. In humans, mutations affecting Kv1.2 function are linked to epileptic encephalopathy and movement disorders. We have demonstrated that Kv1.2 is subject to a unique regulatory (...) . Substitutions of Thr with some sterically similar amino acids (Ser, Val, and Met, but not Cys) retain use-dependent activation, while bulky or charged amino acid substitutions eliminate use-dependence. Introduction of Thr at the equivalent position in other Kv1 channels (1.1, 1.3, 1.4), was not sufficient to transfer the phenotype. We hypothesize that use-dependent activation of Kv1.2 channels is mediated by an extrinsic regulator that binds preferentially to the channel closed state, with Thr252 being

2015 Channels

149. Hydrophobic interactions between the S5 segment and the pore helix stabilizes the closed state of Slo2.1 potassium channels Full Text available with Trip Pro

Hydrophobic interactions between the S5 segment and the pore helix stabilizes the closed state of Slo2.1 potassium channels Under normal physiological conditions, Slo2.1K(+) channels are in a closed state unless activated by an elevation in [Na(+)]i. Fenamates such as niflumic acid also activate Slo2.1. Previous studies suggest that activation of Slo2.1 channels is mediated by a conformational change in the selectivity filter, and not a widening of the aperture formed by the S6 segment bundle (...) crossing as occurs in voltage-gated K(+) channels. It is unclear how binding of Na(+) or fenamates is allosterically linked to opening of the presumed selectivity filter activation gate in Slo2.1. Here we examined the role of the S5 transmembrane segment in the activation of Slo2.1. Channels were heterologously expressed in Xenopus laevis oocytes and whole cell currents measured with the voltage-clamp technique. Ala substitution of five residues located on a single face of the S5 α-helical segment

2015 Biochimica et biophysica acta

150. Sintering of Lead-Free Piezoelectric Sodium Potassium Niobate Ceramics Full Text available with Trip Pro

Sintering of Lead-Free Piezoelectric Sodium Potassium Niobate Ceramics The potassium sodium niobate, K0.5Na0.5NbO₃, solid solution (KNN) is considered as one of the most promising, environment-friendly, lead-free candidates to replace highly efficient, lead-based piezoelectrics. Since the first reports of KNN, it has been recognized that obtaining phase-pure materials with a high density and a uniform, fine-grained microstructure is a major challenge. For this reason the present paper reviews

2015 Materials

151. Sulfonylurea Therapy Benefits Neurological and Psychomotor Functions in Patients With Neonatal Diabetes Owing to Potassium Channel Mutations. Full Text available with Trip Pro

Sulfonylurea Therapy Benefits Neurological and Psychomotor Functions in Patients With Neonatal Diabetes Owing to Potassium Channel Mutations. Neonatal diabetes secondary to mutations in potassium-channel subunits is a rare disease but constitutes a paradigm for personalized genetics-based medicine, as replacing the historical treatment with insulin injections with oral sulfonylurea (SU) therapy has been proven beneficial. SU receptors are widely expressed in the brain, and we therefore (...) , suggesting that the impairments were central in origin.SU therapy in neonatal diabetes secondary to mutations in potassium-channel subunits produces measurable improvements in neuropsychomotor impairments, which are greater in younger patients. An early genetic diagnosis should always be made, allowing for a rapid switch to SU.© 2015 by the American Diabetes Association. Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work

2015 Diabetes Care

152. A Study on the Efficacy of Glucosamine Sulfate Potassium Chloride/Standardized Ginkgo Biloba Leaf Extract in Adults With Osteoarthritis of the Knee.

A Study on the Efficacy of Glucosamine Sulfate Potassium Chloride/Standardized Ginkgo Biloba Leaf Extract in Adults With Osteoarthritis of the Knee. A Study on the Efficacy of Glucosamine Sulfate Potassium Chloride/Standardized Ginkgo Biloba Leaf Extract in Adults With Osteoarthritis of the Knee. - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved (...) Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. A Study on the Efficacy of Glucosamine Sulfate Potassium Chloride/Standardized Ginkgo Biloba Leaf Extract in Adults With Osteoarthritis of the Knee. (13GOHJ) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read

2015 Clinical Trials

153. Clinical study of tegafur-gimeracil-oteracil potassium capsule (s-1) and oxaliplatin combination chemotherapy in advanced colorectal cancer. Full Text available with Trip Pro

Clinical study of tegafur-gimeracil-oteracil potassium capsule (s-1) and oxaliplatin combination chemotherapy in advanced colorectal cancer. The aim of this study was to evaluate the therapeutic efficacy and toxicity of a combination of tegafur-gimeracil-oteracil potassium capsules (S-1) with oxaliplatin for treatment of advanced or recurrent colorectal cancer.Between October 2009 and October 2011, 70 patients at our hospital with advanced or recurrent colorectal cancer were enrolled into our (...) (P > 0.05).The efficacy of the S-1 and oxaliplatin combination regimen in advanced or recurrent colorectal cancer treatment is not inferior to the combination of Xeloda and oxaliplatin and does not result in additional toxicity. Therefore, S-1 could be used to substitute Xeloda in combined chemotherapy with oxaliplatin for the treatment of advanced or recurrent colorectal cancer.

2015 Journal of cancer research and therapeutics Controlled trial quality: uncertain

154. Association of low potassium diet and folic acid deficiency in patients with CKD Full Text available with Trip Pro

to patients with CKD grades 3 and 4 may be associated with folic acid deficiency. Serum levels of folic acid should be investigated before starting potassium restriction in patients with CKD grades 3 and 4, in order to identify individuals with folic acid deficiency or with marginal serum levels who should receive folic acid replacement therapy. (...) Association of low potassium diet and folic acid deficiency in patients with CKD Most of the folic acid sources are rich also in potassium. Patients with chronic kidney disease (CKD) usually receive a low potassium diet. We investigated the possibility of an association between low potassium diet and folic acid deficiency.In total, 128 CKD patients participated in this cross-sectional study. Sixty-four patients with CKD grades 1 and 2 were on an unrestricted potassium diet when enrolled

2015 Therapeutics and clinical risk management

155. Partial substitution of sodium with potassium in white bread: feasibility and bioavailability. (Abstract)

Partial substitution of sodium with potassium in white bread: feasibility and bioavailability. A high sodium intake, to which bread makes a major contribution, and a low potassium intake are believed to be important factors in the promotion of cardiovascular disease. Our aims was to determine to what extent salts of potassium could substitute sodium chloride and potassium-rich soya flour could replace wheat flour without detrimental effect on acceptability, and to measure the bioavailability (...) of a potassium salt added to bread. A single-blind organoleptic evaluation was carried out on eight different potassium-enriched breads by 41 panellists. Thereafter, six volunteers consumed standard or potassium-chloride-fortified bread in an 11-day single-blind cross-over feeding trial to determine the bioavailability of the supplemental potassium. Two breads in which 30% of the sodium was replaced by potassium salts, and bread in which 10% of wheat flour was replaced with soy flour, had acceptability

2012 International journal of food sciences and nutrition Controlled trial quality: uncertain

156. Inspired Helium for Ischemic Protection During Knee Replacement Surgery

Inspired Helium for Ischemic Protection During Knee Replacement Surgery Inspired Helium for Ischemic Protection During Knee Replacement Surgery - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Inspired (...) Helium for Ischemic Protection During Knee Replacement Surgery The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT02012361 Recruitment Status : Completed First Posted : December 16, 2013 Last Update Posted : August 29, 2016 Sponsor: University of Florida Information provided by (Responsible Party

2013 Clinical Trials

157. Standard versus accelerated initiation of renal replacement therapy in acute kidney injury (STARRT-AKI): study protocol for a randomized controlled trial. Full Text available with Trip Pro

of fulfilling eligibility. In the standard initiation arm, participants will be monitored over 7 days to identify indications for renal replacement therapy. For participants in the standard arm with persistent acute kidney injury, defined as a serum creatinine not declining >50% from the value at the time of eligibility, the initiation of RRT will be discouraged unless one or more of the following criteria are fulfilled: serum potassium ≥6.0 mmol/L; serum bicarbonate ≤10 mmol/L; severe respiratory failure (...) Standard versus accelerated initiation of renal replacement therapy in acute kidney injury (STARRT-AKI): study protocol for a randomized controlled trial. Acute kidney injury is a common and devastating complication of critical illness, for which renal replacement therapy is frequently needed to manage severe cases. While a recent systematic review suggested that "earlier" initiation of renal replacement therapy improves survival, completed trials are limited due to small size, single-centre

2013 Trials Controlled trial quality: predicted high

158. Characterization of Khorasan wheat (Kamut) and impact of a replacement diet on cardiovascular risk factors: cross-over dietary intervention study. Full Text available with Trip Pro

potassium and magnesium. Circulating levels of key pro-inflammatory cytokines (interleukin (IL)-6, IL-12, tumour necrosis factor-α and vascular endothelial growth factor) were significantly reduced after the consumption of Kamut products.The present results suggest that a replacement diet with Kamut products could be effective in reducing metabolic risk factors, markers of both oxidative stress and inflammatory status. (...) Characterization of Khorasan wheat (Kamut) and impact of a replacement diet on cardiovascular risk factors: cross-over dietary intervention study. Khorasan wheat (Kamut) is an ancient grain with widely acclaimed beneficial effects on human health. The objective was to characterise Kamut and to examine the effect of a replacement diet with their products on cardiovascular risk parameters.We conducted a randomized, single-blinded cross-over trial with two intervention phases on 22 healthy

2013 European journal of clinical nutrition Controlled trial quality: uncertain

159. Fatality after Cardiac Arrest in Thyrotoxic Periodic Paralysis due to Profound Hypokalemia Resulting from Intravenous Glucose Administration and Inadequate Potassium Replacement. (Abstract)

Fatality after Cardiac Arrest in Thyrotoxic Periodic Paralysis due to Profound Hypokalemia Resulting from Intravenous Glucose Administration and Inadequate Potassium Replacement.

2012 Thyroid

160. A Novel Regulatory Locus of Phosphorylation in the C Terminus of the Potassium Chloride Cotransporter KCC2 That Interferes with N-Ethylmaleimide or Staurosporine-mediated Activation Full Text available with Trip Pro

A Novel Regulatory Locus of Phosphorylation in the C Terminus of the Potassium Chloride Cotransporter KCC2 That Interferes with N-Ethylmaleimide or Staurosporine-mediated Activation The neuron-specific cation chloride cotransporter KCC2 plays a crucial role in hyperpolarizing synaptic inhibition. Transporter dysfunction is associated with various neurological disorders, raising interest in regulatory mechanisms. Phosphorylation has been identified as a key regulatory process. Here, we retrieved (...) experimentally observed phosphorylation sites of KCC2 from public databases and report on the systematic analysis of six phosphorylated serines, Ser(25), Ser(26), Ser(937), Ser(1022), Ser(1025), and Ser(1026). Alanine or aspartate substitutions of these residues were analyzed in HEK-293 cells. All mutants were expressed in a pattern similar to wild-type KCC2 (KCC2(WT)). Tl(+) flux measurements demonstrated unchanged transport activity for Ser(25), Ser(26), Ser(1022), Ser(1025), and Ser(1026) mutants

2014 The Journal of biological chemistry

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