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Potassium Replacement

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121. A Study on the Efficacy of Glucosamine Sulfate Potassium Chloride/Standardized Ginkgo Biloba Leaf Extract in Adults With Osteoarthritis of the Knee.

A Study on the Efficacy of Glucosamine Sulfate Potassium Chloride/Standardized Ginkgo Biloba Leaf Extract in Adults With Osteoarthritis of the Knee. A Study on the Efficacy of Glucosamine Sulfate Potassium Chloride/Standardized Ginkgo Biloba Leaf Extract in Adults With Osteoarthritis of the Knee. - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved (...) Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. A Study on the Efficacy of Glucosamine Sulfate Potassium Chloride/Standardized Ginkgo Biloba Leaf Extract in Adults With Osteoarthritis of the Knee. (13GOHJ) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read

2015 Clinical Trials

122. Clinical study of tegafur-gimeracil-oteracil potassium capsule (s-1) and oxaliplatin combination chemotherapy in advanced colorectal cancer. Full Text available with Trip Pro

Clinical study of tegafur-gimeracil-oteracil potassium capsule (s-1) and oxaliplatin combination chemotherapy in advanced colorectal cancer. The aim of this study was to evaluate the therapeutic efficacy and toxicity of a combination of tegafur-gimeracil-oteracil potassium capsules (S-1) with oxaliplatin for treatment of advanced or recurrent colorectal cancer.Between October 2009 and October 2011, 70 patients at our hospital with advanced or recurrent colorectal cancer were enrolled into our (...) (P > 0.05).The efficacy of the S-1 and oxaliplatin combination regimen in advanced or recurrent colorectal cancer treatment is not inferior to the combination of Xeloda and oxaliplatin and does not result in additional toxicity. Therefore, S-1 could be used to substitute Xeloda in combined chemotherapy with oxaliplatin for the treatment of advanced or recurrent colorectal cancer.

2015 Journal of cancer research and therapeutics Controlled trial quality: uncertain

123. Association of low potassium diet and folic acid deficiency in patients with CKD Full Text available with Trip Pro

to patients with CKD grades 3 and 4 may be associated with folic acid deficiency. Serum levels of folic acid should be investigated before starting potassium restriction in patients with CKD grades 3 and 4, in order to identify individuals with folic acid deficiency or with marginal serum levels who should receive folic acid replacement therapy. (...) Association of low potassium diet and folic acid deficiency in patients with CKD Most of the folic acid sources are rich also in potassium. Patients with chronic kidney disease (CKD) usually receive a low potassium diet. We investigated the possibility of an association between low potassium diet and folic acid deficiency.In total, 128 CKD patients participated in this cross-sectional study. Sixty-four patients with CKD grades 1 and 2 were on an unrestricted potassium diet when enrolled

2015 Therapeutics and clinical risk management

124. A Study on the Efficacy and Safety of Continuous Renal Replacement Therapy (CVVHDF) Using a Commercial Citrate-containing Replacement Fluid (Prismocitrate 18/0)

] filter lifespan will be recorded as the time duration from commencement of renal replacement therapy till filter clotted or therapy ended Secondary Outcome Measures : metabolic and electrolyte control [ Time Frame: up to 4days ] Serum electrolytes (calcium, sodium, potassium, magnesium, acid-base)will be monitored at baseline, then every 6 hours onwards during the CRRT bleeding/transfusion requirement [ Time Frame: up to 4 days ] blood counts including the hemoglobin level and patient clinical status (...) A Study on the Efficacy and Safety of Continuous Renal Replacement Therapy (CVVHDF) Using a Commercial Citrate-containing Replacement Fluid (Prismocitrate 18/0) A Study on the Efficacy and Safety of Continuous Renal Replacement Therapy (CVVHDF) Using a Commercial Citrate-containing Replacement Fluid (Prismocitrate 18/0) - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study

2013 Clinical Trials

125. Launching a Salt Substitute to Reduce Blood Pressure at the Population Level in Peru

Collaborator: Johns Hopkins University Information provided by (Responsible Party): Jaime Miranda, Universidad Peruana Cayetano Heredia Study Details Study Description Go to Brief Summary: This protocol aims to implement, using a stepped wedge trial design, a population-level intervention to replace high-sodium salt for a salt substitute (low-sodium, high-potassium salt) to reduce blood pressure levels among adults aged 18 years and over of the semi-urban area of Tumbes. We hypothesize that participants (...) aged 18 years and over from villages receiving a salt substitute will have lower blood pressure compared to control villages. Condition or disease Intervention/treatment Phase Blood Pressure Hypertension Other: Salt substitute Not Applicable Detailed Description: Several randomized clinical trials and meta-analysis have reported that reduction of sodium intake decreases blood pressure. Also, the increase of potassium ingestion in minimal doses has been found in systematic reviews to produce a small

2013 Clinical Trials

126. Long-term effects of salt substitution on blood pressure in a rural north Chinese population. Full Text available with Trip Pro

Long-term effects of salt substitution on blood pressure in a rural north Chinese population. Dietary sodium and potassium intake can influence blood pressure. The effects of salt substitution on patients with hypertension and normotensive family member controls, however, have not been evaluated in a rural Chinese population. The objective of this study, accordingly, was to assess the long-term effects of salt substitution on blood pressure. We conducted a double-blind, randomized controlled (...) trial among 200 families in rural China to establish the 2-year effects of a reduced-sodium, high-potassium salt substitute (65% sodium chloride, 25% potassium chloride, 10% magnesium sulfate) compared with normal salt (100% sodium chloride) on blood pressure. Of the 462 individuals in the trial, 372 completed the study (81%). For normotensive subjects, the mean overall difference in systolic and diastolic blood pressure between the two groups at the 24-month follow-up was 2 mm Hg (95% confidence

2013 Journal of human hypertension Controlled trial quality: predicted high

127. THE SELECTIVE ABSORPTION OF POTASSIUM BY ANIMAL CELLS : II. THE CAUSE OF POTASSIUM SELECTION AS INDICATED BY THE ABSORPTION OF RUBIDIUM AND CESIUM. Full Text available with Trip Pro

THE SELECTIVE ABSORPTION OF POTASSIUM BY ANIMAL CELLS : II. THE CAUSE OF POTASSIUM SELECTION AS INDICATED BY THE ABSORPTION OF RUBIDIUM AND CESIUM. 1. Frog muscles perfused with Ringer solution in which potassium chloride has been replaced by an equivalent amount of rubidium or cesium chloride take up rubidium or cesium and incorporate them into the tissue substance in such form as to be retained during a subsequent perfusion with potassium-free Ringer solution, provided the muscles contract (...) during the first perfusion. Retention of rubidium or cesium by a resting muscle does not occur. 2. Rats on synthetic diets, adequate in all respects except that potassium was replaced by an equivalent amount of rubidium or cesium, died after a period varying from 10 to 17 days with characteristic symptoms including tetanic spasms. Muscle, heart, liver, kidney, spleen, and lung tissues were then found to contain significant amounts of rubidium or cesium. The concentration of these metals in the muscle

1921 The Journal of general physiology

128. Intracellular Potassium : A Determinant of the Sodium-Potassium Pump Rate Full Text available with Trip Pro

Intracellular Potassium : A Determinant of the Sodium-Potassium Pump Rate Normal human red cells which have had their intracellular sodium (Na(c)) reduced have a diminished Na-K pump rate, but only if intracellular potassium (K(c)) is high. If most of the K(c) is replaced by tetramethylammonium or choline, both ouabain-sensitive Na efflux and K influx are significantly increased even with Na(c) below normal. Cells with reduced Na(c) and high K(c) have an unchanged Na efflux if external (...) potassium (K(ext)) is removed. In contrast, low-Na, low-K cells have a large ouabain-sensitive Na efflux which shows a normal response to removal of K(ext). Neither low-K nor high-K cells have an altered ouabain-sensitive K efflux. Measurement at constant low Na(c) and varying K(c) shows the pump Na efflux to be an inverse function of K(c). Thus, in low-Na cells, K(c) appears to act as an inhibitor of the pump. Inhibition by high K(c) can be seen even when Na(c) is normal. The effects attributed to K(c

1974 The Journal of general physiology

129. Potassium: potassium exchange catalysed by the sodium pump in human red cells Full Text available with Trip Pro

Potassium: potassium exchange catalysed by the sodium pump in human red cells 1. When red cells were so depleted of Na that Na:K exchange had almost ceased, the ouabain-sensitive K efflux seen in K-containing media was accompanied by an almost equal ouabain-sensitive K influx.2. This suggests that the Na pump in these cells was carrying out a one-for-one K:K exchange across the erythrocyte membrane.3. 30-40% of the (42)K efflux from resealed ghosts was sensitive to ouabain when the ghosts (...) exchange did not depend on whether the ADP concentration was roughly the same as the ATP concentration or very much less, suggesting that ADP did not affect the rate of K:K exchange.7. GTP, ITP and UTP were unable to substitute for ATP in supporting K:K exchange. CTP was a poor substitute.8. There was no evidence to support the hypothesis that K:K exchange is accompanied by a ouabain-sensitive hydrolysis of ATP.9. Internal Na was a strong inhibitor of ouabain-sensitive K efflux from ghosts containing 9

1974 The Journal of physiology

130. Potassium depletion and sodium block of potassium currents under hyperpolarization in frog sartorius muscle. Full Text available with Trip Pro

Potassium depletion and sodium block of potassium currents under hyperpolarization in frog sartorius muscle. 1. A three-electrode voltage clamp method was used to investigate the mechanism of the fall in resting potassium permeability which occurs under extreme hyperpolarization in frog sartorius muscle fibres. 2. Experiments were performed which show that this permeability change is due to a potential dependent block by Na+ ions present in the external solution. 3. Inward K-currents recorded (...) on hyperpolarization turned off exponentially with time. In the presence of Na the steady-state current-voltage relation had a region of negative slope beyond -140 mV. This negative-slope region was removed when Na was replaced by TMA, Tris or Li. Increasing [Na] to 140 mM shifted the negative-slope region to less negative membrane potentials; reducing [Na] to 14 mM shifted the region to more negative potentials. 4. The time constant for the turn-off of the currents (tau) was the same in Na and TMA-containing

1979 The Journal of physiology

131. The relation between external potassium concentration and the relaxation rate of potassium-induced contractures in frog skeletal muscle Full Text available with Trip Pro

The relation between external potassium concentration and the relaxation rate of potassium-induced contractures in frog skeletal muscle 1. Frog toe muscles and isolated fibres from frog semitendinosus muscles were allowed to develop maximum K-contractures, and after reaching peak tension were transferred to media containing intermediate [K](0) (20-40 mM-K). Under these circumstances, relaxation displayed an early rapid phase, and a subsequent slower phase whose magnitude and rate varied with [K (...) alterations in [Ca](0) or by sudden replacement of the major extracellular anion. These effects are attributed to shifts in the relation between calcium rebinding and membrane potential.

1966 The Journal of physiology

132. The Impact of Neut During KCL Replacement on Pain and Incidence of Phlebitis

The Impact of Neut During KCL Replacement on Pain and Incidence of Phlebitis The Impact of Neut During Potassium Chloride Replacement on Pain and Incidence of Phlebitis - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before (...) adding more. The Impact of Neut During Potassium Chloride Replacement on Pain and Incidence of Phlebitis (Neut-WKBH) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT02082717 Recruitment Status : Enrolling by invitation First Posted : March 10, 2014 Last Update Posted : February 5, 2018 Sponsor

2014 Clinical Trials

133. Effect of Perioperative Glucocorticoid Replacement on Prognosis of Surgical Patients With Sellar Lesions

Effect of Perioperative Glucocorticoid Replacement on Prognosis of Surgical Patients With Sellar Lesions Effect of Perioperative Glucocorticoid Replacement on Prognosis of Surgical Patients With Sellar Lesions - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100 (...) ). Please remove one or more studies before adding more. Effect of Perioperative Glucocorticoid Replacement on Prognosis of Surgical Patients With Sellar Lesions The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT02190994 Recruitment Status : Unknown Verified July 2014 by Shu Jiang, West China Hospital

2014 Clinical Trials

134. Potassium Board Review - New Wash U Nephrology Web Episode

Potassium Board Review - New Wash U Nephrology Web Episode Renal Fellow Network: Potassium Board Review - New Wash U Nephrology Web Episode | | | | | Tuesday, June 14, 2016 Potassium Board Review - New Wash U Nephrology Web Episode Hypokalemia, hypertension, and metabolic alkalosis - this clinical triad can be seen in a variety of interesting disorders that unfortunately are much more common during in-training or board certification exams than in clinical practice. That doesn't mean you should (...) cram for them the night before the exam! Understanding the way these diseases affect potassium handling in the kidney can help learners of all levels acquire a better understanding of normal renal physiology. This month's nephrology web episode from Washington University in St. Louis focuses on 4 board-style questions related to potassium disorders, and we hope you find it helpful. The full episode can be viewed below: Posted by Timothy Yau at 2 comments: said... Nice post. I have 2 comments

2016 Renal Fellow Network

135. Potassium Hydroxide Impregnated Alumina (KOH-Alumina) as a Recyclable Catalyst for the Solvent-Free Multicomponent Synthesis of Highly Functionalized Substituted Pyridazines and/or Substituted Pyridazin-3(2H)-ones under Microwave Irradiation Full Text available with Trip Pro

Potassium Hydroxide Impregnated Alumina (KOH-Alumina) as a Recyclable Catalyst for the Solvent-Free Multicomponent Synthesis of Highly Functionalized Substituted Pyridazines and/or Substituted Pyridazin-3(2H)-ones under Microwave Irradiation The work described herein employs potassium hydroxide impregnated alumina (KOH-alumina) as a mild, efficient, and recyclable catalyst for a one-pot solvent-free and environmentally safer synthesis of 3,4,6-triarylpyridazines and some substituted pyridazines

2011 ISRN organic chemistry

136. Severe Hyperkalemia in a Peritoneal Dialysis Patient After Consumption of Salt Substitute Full Text available with Trip Pro

Severe Hyperkalemia in a Peritoneal Dialysis Patient After Consumption of Salt Substitute 22383720 2012 06 19 2018 11 13 1718-4304 32 2 2012 Mar-Apr Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis Perit Dial Int Severe hyperkalemia in a peritoneal dialysis patient after consumption of salt substitute. 206-8 10.3747/pdi.2011.00198 Yip Terence T Dr. Lee Iu Cheung Memorial Renal Research Centre, Tung Wah Hospital, The University of Hong Kong, Hong (...) Kong SAR, PR China. yipterence@gmail.com Wan Winnie W Hui Pui-Chi PC Lui Sing-Leung SL Lo Wai-Kei WK eng Case Reports Journal Article Canada Perit Dial Int 8904033 0896-8608 0 Potassium, Dietary 660YQ98I10 Potassium Chloride IM Condiments adverse effects Female Humans Hyperkalemia etiology therapy Kidney Failure, Chronic therapy Middle Aged Peritoneal Dialysis, Continuous Ambulatory Potassium Chloride adverse effects Potassium, Dietary adverse effects 2012 3 3 6 0 2012 3 3 6 0 2012 6 20 6 0

2012 Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis

137. BIOELECTRIC POTENTIALS IN VALONIA : THE EFFECT OF SUBSTITUTING KCl FOR NaCl IN ARTIFICIAL SEA WATER Full Text available with Trip Pro

BIOELECTRIC POTENTIALS IN VALONIA : THE EFFECT OF SUBSTITUTING KCl FOR NaCl IN ARTIFICIAL SEA WATER The P.D. across the protoplasm of Valonia macrophysa has been studied while the cells were exposed to artificial solutions resembling sea water in which the concentration of KCl was varied from 0 to 0.500 mol per liter. The P.D. across the protoplasm is decreased by lowering and increased by raising the concentration of KCl in the external solution. Changes in P.D. with time when the cell (...) .-time curve have been interpreted as indicating that potassium enters Valonia protoplasm more rapidly from alkaline than from acidified KCl-rich sea water. This conclusion is discussed in relation to certain theories which have been proposed to explain the accumulation of KCl in Valonia sap. The initial rise in P.D. when a Valonia cell is transferred from natural sea water to KCl-rich sea water has been correlated with the concentrations of KCl in the sea waters. It is assumed that the observed P.D

1932 The Journal of general physiology

138. STUDIES ON CELL METABOLISM AND CELL DIVISION : IV. COMBINED ACTION OF SUBSTITUTED PHENOLS, CYANIDE, CARBON MONOXIDE, AND OTHER RESPIRATORY INHIBITORS ON RESPIRATION AND CELL DIVISION Full Text available with Trip Pro

, by phenylurethane, by 5-isoamyl-5-ethyl barbituric acid, by malonic acid, or by iodoacetic acid. To abolish all respiratory stimulation by suboptimum concentrations of 4,6-dinitro-o-cresol, each of these inhibitors must be present in a concentration which reduces the normal respiration in the absence of substituted phenols by at least 20-40 per cent. 2. The degree of reduction of the stimulated respiration by a given concentration of carbon monoxide or potassium cyanide depends on the concentration of 4,6 (...) STUDIES ON CELL METABOLISM AND CELL DIVISION : IV. COMBINED ACTION OF SUBSTITUTED PHENOLS, CYANIDE, CARBON MONOXIDE, AND OTHER RESPIRATORY INHIBITORS ON RESPIRATION AND CELL DIVISION The effects of 4,6-dinitro-o-cresol and 2,4,5-trichlorophenol on the respiration and cell division of fertilized eggs of Arbacia punctulata have been determined in the presence of each of a number of respiratory inhibitors. The experimental results obtained appear to afford some understanding of the mechanism

1940 The Journal of general physiology

139. Substitute for agar in solid media for common usages in microbiology. Full Text available with Trip Pro

Substitute for agar in solid media for common usages in microbiology. The potassium salt of carrageenan was found to be an adequate replacement for agar in solid bacteriological media. The common microbial genetic techniques, such as purifying colonies by streaking, replication tests, and titration of cultures, were carried out sucessfully with a number of mutant strains of Escherichia coli.

1976 Applied and environmental microbiology

140. Blocking of valinomycin-mediated bilayer membrane conductance by substituted benzimidazoles. Full Text available with Trip Pro

Blocking of valinomycin-mediated bilayer membrane conductance by substituted benzimidazoles. Valinomycin selectively transports alkali cations, e.g. potassium ions, across lipid bilayer membranes. The blocking of this carrier-mediated transport by four substituted benzimidazoles has been investigated. The compounds are 4,5,6,7-tetrachloro-2-trifluoromethylbenzimidazole, (TTFB); 4,5,6,7,-tetrachloro-2-methylbenzimidazole, (TMB); 2-trifluoromethylbenzimidazole, (TFB); and 2-methylbenzimidazole

1976 Biophysical journal

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