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Potassium Replacement

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4221. Ultrastructure of rat initial collecting tubule. Effect of adrenal corticosteroid treatment. Full Text available with Trip Pro

Ultrastructure of rat initial collecting tubule. Effect of adrenal corticosteroid treatment. This study examines the effects of adrenalectomy and physiological replacement of mineralocorticoids and glucocorticoids on the cellular ultrastructure of the rat initial collecting tubule (late distal tubule). Animals were adrenalectomized (ADX) and for 10 d received by osmotic minipump either: vehicle, aldosterone (0.5 micrograms X 100 g-1 X d-1), aldosterone (2.0 micrograms X 100 g-1 X d-1 (...) by 35% in ADX animals. Low dose aldosterone replacement (0.5 micrograms X 100 g-1 X d-1) in ADX animals maintained membrane length at control values; at a higher level of aldosterone (2.0 micrograms X 100 g-1 X d-1) membrane length increased by 111% compared with control. Dexamethasone treatment, at a level that restored glomerular filtration rate to normal, had no effect on cellular ultrastructure. Combined aldosterone and dexamethasone replacement had no greater effect on basolateral membrane

1985 Journal of Clinical Investigation

4222. Effet, sur quelques paramètres sanguins, de l'addition de tourteau de canola CV. Tower à la ration des truies Full Text available with Trip Pro

Effet, sur quelques paramètres sanguins, de l'addition de tourteau de canola CV. Tower à la ration des truies EFFECT OF THE ADDITION OF CANOLA CV. TOWER MEAL TO THE RATION OF SOWS ON SOME OF THEIR BLOOD PARAMETERS: The effect of substituting in sow diet soybean meal by canola meal (10%) and litter size on different blood constituents were studied. At day 110 of pregnancy, at weaning and at day 3 of the estrous cycle following weaning, canola meal and litter size did not affect the levels (...) of calcium, phosphorus, magnesium, sodium, potassium, total protein and blood urea nitrogen. However, some blood parameters varied significantly among physiological stages for the same animal. Within physiological stages, large differences were observed between animals for some metabolites.

1983 The Canadian Veterinary Journal

4223. Fluid therapy trials in neonatal piglets infected with transmissible gastroenteritis virus. Full Text available with Trip Pro

were used as controls (Group 1). At the onset of diarrhea, infected piglets were divided into three groups of six (Groups 2, 3 and 4). Piglets in group 2 were not treated and were fed a milk replacer ad libitum. Piglets in group 3 were removed from the milk replacer and placed on an oral glucose-glycine-electrolyte solution ad libitum. Those in group 4 were placed on oral fluid therapy and received a 5% dextrose solution intraperitoneally at the rate of 25 mL/kg of body weight once a day. Blood (...) samples were collected in heparin within minutes after the infected piglets became comatose and from the controls at four or five days of age. The following variables were measured: packed red cell volume, blood pH, total plasma protein and bicarbonate, blood urea nitrogen, and plasma glucose, creatinine, chloride, inorganic phosphorus, sodium, potassium, magnesium and calcium. Vomiting and diarrhea appeared 12 to 24 hours postinoculation in the infected piglets. There was a sudden and rapid

1985 Canadian Journal of Comparative Medicine

4224. Inhibitin: a specific inhibitor of sodium/sodium exchange in erythrocytes. Full Text available with Trip Pro

not inhibit sodium-potassium-ATPase activity. The inhibitory effect of inhibitin was studied on sodium/sodium exchange and on sodium/lithium countertransport in 140 mM sodium and in sodium-free media. In the presence of sodium, inhibitin reduced sodium and lithium efflux to that observed in sodium-free medium. Inhibitin showed no reduction in sodium or lithium efflux when sodium was replaced by choline chloride or Mg2+. When inhibitin was combined with one or more of the other transport inhibitors (i.e

1986 Journal of Clinical Investigation

4225. 99mTc-pertechnetate uptake in parotid acinar cells by the Na+/K+/Cl- co-transport system. Full Text available with Trip Pro

parotid acinar cells. 99mTcO4- uptake by these cells was quite rapid (t1/2 approximately 30 s), was completely inhibited by the loop diuretics furosemide and bumetanide, and was markedly dependent on the presence of Na+, K+, and Cl- in the extracellular medium. Relative to uptake measured in the presence of physiological extracellular salt concentrations (Hanks' salts), 99mTcO4- uptake was inhibited 80% by sodium replacement and 50% by potassium replacement. When Cl- was replaced (...) with the physiologically inert anion gluconate a threefold stimulation in 99mTcO4- uptake resulted. These observations provide strong evidence that 99mTcO4- can substitute for Cl- as a substrate for the Na+/K+/Cl- co-transporter and indicate that 99mTcO4- uptake by salivary glands (e.g., as seen with salivary scintiscans), and possibly by a variety of other tissues, reflects the functional activity of this co-transport mechanism.

1987 Journal of Clinical Investigation

4226. Hypokalemic myopathy in pregnancy caused by clay ingestion. (Abstract)

Hypokalemic myopathy in pregnancy caused by clay ingestion. We present a case of severe hypokalemic myopathy during pregnancy caused by clay ingestion.A multigravida presented with fatigue, muscle weakness, and a 3-day history of extremity pain. Serum potassium levels were 1.5 mEq/L, requiring intravenous potassium replacement. The initial evaluation was unrewarding for the cause of the patient's hypokalemia until a family member reported that the patient frequently ate large quantities of clay (...) . Discontinuation of clay ingestion led to normalization of potassium levels.Pica, the persistent ingestion of nonnutritive substances, can cause a number of medical problems. Pica of clay, called geophagia, can bind potassium in the intestine, leading to severe hypokalemic myopathy. Clinicians caring for pregnant women with fatigue, muscle weakness, and hypokalemia should consider geophagia as a possible cause.

2003 Obstetrics and Gynecology

4227. Neutralization of Western diet inhibits bone resorption independently of K intake and reduces cortisol secretion in humans. Full Text available with Trip Pro

acid load acts directly or indirectly (i.e., via endocrine changes) on bone metabolism. It is also unclear whether alkali administration affects bone resorption/calcium balance directly or whether alkali-induced calcium retention is dependent on the cation (i.e., potassium) supplied with administered base. The effects of neutralization of dietary acid load (equimolar amounts of NaHCO(3) and KHCO(3) substituted for NaCl and KCl) in nine healthy subjects (6 men, 3 women) under metabolic balance

2003 American Journal of Physiology. Renal physiology

4228. Acute renal failure due to crush syndrome during Marmara earthquake. (Abstract)

Acute renal failure due to crush syndrome during Marmara earthquake. During the earthquake in Marmara, Turkey (August 17, 1999), 87 of 476 victims (18.3%) admitted to Marmara University Hospital (Istanbul, Turkey) experienced renal failure caused by crush injuries. Fifty-nine patients (68%; 40 men, 19 women) required renal replacement therapy (RRT), whereas 28 patients (32%; 20 men, 16 women) recovered renal function under conservative treatment. The aim of the present study is to compare (...) compared with those who recovered under conservative treatment. Patients who required RRT had significantly less urine output in the first 24 hours, underwent more fasciotomies, and needed more blood and fresh frozen plasma transfusions (P < 0.05). Blood urea nitrogen, creatinine, potassium, creatine kinase, and aspartate aminotransferase levels were significantly greater compared with patients managed conservatively both on admission and for the mean of values obtained during the first 2 weeks (P

2002 American Journal of Kidney Diseases

4229. The sweating response of elite professional soccer players to training in the heat. (Abstract)

instructed to drink only from their own bottles and not to spit out any drink. No player urinated during the training session. Sweat was collected by patches from the chest, arm, back, and thigh of a subgroup of 7 players. These remained in place for the first 15 - 30 min of the training session, and sweat was analysed for sodium (Na (+)) and potassium (K (+)) concentration. Body mass loss was 1.23 +/- 0.50 kg (ranging from 0.50 to 2.55 kg), equivalent to dehydration of 1.59 +/- 0.61 % of pre-training (...) body mass. The sweat volume lost was 2193 +/- 365 ml (1672 to 3138 ml), but only 972 +/- 335 ml (239 to 1724 ml) of fluid was consumed. 45 +/- 16 % of the sweat volume loss was replaced, but this ranged from 9 % to 73 %. The Na (+) concentration of the subgroup's sweat was 30.2 +/- 18.8 mmol/l (15.5 to 66.3 mmol/l) and Na (+) losses averaged 67 +/- 37 mmol (26 to 129 mmol). The K (+) concentration of the sweat was 3.58 +/- 0.56 mmol/l (2.96 to 4.50 mmol/l) and K (+) losses averaged 8 +/- 2 mmol (5

2005 International Journal of Sports Medicine

4230. Hydration status in college football players during consecutive days of twice-a-day preseason practices. (Abstract)

Hydration status in college football players during consecutive days of twice-a-day preseason practices. Football players lose 3.5 to 5 kg of body weight during preseason practices because of heavy sweating. This fluid may be difficult to replace when practices occur 2 times per day on consecutive days.Football players are hypohydrated during twice-a-day preseason training in a hot, humid environment.Descriptive laboratory study.In 10 college football players, body weight was measured (...) , and blood and urine samples were obtained before and after practices on days 2 through 8 of preseason training. Baseline samples were obtained when subjects were euhydrated. Blood samples were used to calculate plasma volume changes. Urine samples were analyzed for specific gravity, sodium, and potassium. Sweat rate was calculated. Core temperature was monitored during half- and full-padded practices.Mean wet bulb temperatures were 23.3 degrees C during morning practices and 23.7 degrees C during

2005 American Journal of Sports Medicine

4231. Pharmacology and therapeutic effects of dehydroepiandrosterone in older subjects. (Abstract)

is a neurosteroid which modulates neuronal excitability via specific interactions with neurotransmitter receptors and DHEA is an activator of calcium-gated potassium channels. Randomised, placebo-controlled clinical trials which included healthy individuals aged 60 years and over treated with (near) physiological doses of DHEA (50-100 mg/day) have yielded very few positive results. Impact of DHEA replacement treatment was assessed on mood, well being, cognitive and sexual functions, bone mass, body composition (...) , vascular risk factors, immune functions and skin. The major limitations of these trials were their short duration (maximum 1 year) and the low number of study participants involved (maximum 280). Many elderly people in western countries take DHEA without medical supervision. In the US, DHEA is even classified as food supplement. At present there is no scientific evidence to recommend DHEA replacement in the elderly. Further studies are needed to form conclusions about the efficacy and the safety

2003 Drugs & Aging

4232. Mannopeptimycins, new cyclic glycopeptide antibiotics produced by Streptomyces hygroscopicus LL-AC98: antibacterial and mechanistic activities. Full Text available with Trip Pro

Mannopeptimycins, new cyclic glycopeptide antibiotics produced by Streptomyces hygroscopicus LL-AC98: antibacterial and mechanistic activities. Mannopeptimycins alpha, beta, gamma, delta, and epsilon are new cyclic glycopeptide antibiotics produced by Streptomyces hygroscopicus LL-AC98. Mannopeptimycins gamma, delta, and epsilon, which have an isovaleryl substitution at various positions on the terminal mannose of the disaccharide moiety, demonstrated moderate to good antibacterial activities (...) . Mannopeptimycin epsilon was the most active component against methicillin-resistant staphylococci and vancomycin-resistant enterococci (MICs, 2 to 4 micro g/ml for staphylococci and streptococci and 4 to 32 micro g/ml for enterococci), while mannopeptimycins gamma and delta were two- to fourfold less active. Mannopeptimycins alpha and beta, which lack the isovaleryl substitution and the disaccharide moiety, respectively, had poor antibacterial activities. The in vivo efficacies of the mannopeptimycins

2003 Antimicrobial Agents and Chemotherapy

4233. Cardioprotective actions by a water-soluble carbon monoxide-releasing molecule. Full Text available with Trip Pro

performance and a marked and significant reduction in cardiac muscle damage and infarct size. The cardioprotective effects mediated by CORM-3 in cardiac cells and isolated hearts were totally abolished by 5-hydroxydecanoic acid, an inhibitor of mitochondrial ATP-dependent potassium channels. Predictably, cardioprotection is lost when CORM-3 is replaced by an inactive form (iCORM-3) that is incapable of liberating CO. Using a model of cardiac allograft rejection in mice, we also found that treatment

2003 Circulation Research

4234. Recovery of high blood pressure after chronic lesions of the commissural NTS in SHR. Full Text available with Trip Pro

Recovery of high blood pressure after chronic lesions of the commissural NTS in SHR. Acute electrolytic lesions of the commissural nucleus of the solitary tract (commNTS) reduce blood pressure (BP) in SHR but not in normotensive Wistar-Kyoto and Wistar rats and abolish the pressor response to intravenous injection of potassium cyanide. We investigated the chronic effect of commNTS lesions on mean arterial pressure (MAP), and on baroreceptor and chemoreceptor reflex responses in SHR (...) . The contribution of the sympathetic nervous system and the hormones vasopressin and angiotensin II to maintenance of BP in lesioned SHR was also investigated. MAP fell to normotensive levels the day after lesioning the commNTS but returned to the hypertensive level 9 days later. The reflex tachycardia evoked by sodium nitroprusside remained attenuated for 10 days after commNTS lesions but became enhanced 30 days after commNTS lesions. The pressor component of the chemoreflex elicited by potassium cyanide

2003 Hypertension

4235. Nonhalogenated alkanes cyclopropane and butane affect neurotransmitter-gated ion channel and G-protein-coupled receptors: differential actions on GABAA and glycine receptors. (Abstract)

, but yielded barely detectable potentiation of GABA(A) receptors. The efficacy of cyclopropane for glycine receptors was less than isoflurane and halothane. The potentiation by cyclopropane was eliminated for the alpha1(S267C) glycine receptor. Mutant GABA(A) receptors in which the corresponding amino acid was substituted with larger amino acids did not produce significant potentiation. Cyclopropane and butane inhibited nicotinic acetylcholine and N-methyl-D-aspartate receptors, potentiated G-protein (...) -coupled inwardly rectifying potassium channels, and did not change 5-hydroxytryptamine(3A) or muscarinic(1) receptor function. Only cyclopropane markedly inhibited alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptors.Glycine, nicotinic acetylcholine, and N-methyl-D-aspartate receptors are sensitive to nonhalogenated alkanes, and the authors propose that glycine and N-methyl-D-aspartate receptors are good candidates for anesthetic immobility. The authors also suggest that the distinct

2002 Anesthesiology

4236. Factors influencing the restoration of fluid and electrolyte balance after exercise in the heat. Full Text available with Trip Pro

promote a diuretic response. If effective rehydration is to be maintained for some hours after fluid ingestion, drinks should contain moderately high levels of sodium (perhaps as much as 50-60 mmol/l) and possibly also some potassium to replace losses in the sweat. To surmount ongoing obligatory urine losses, the volume consumed should be greater than the volume of sweat lost. Palatability of drinks is important in stimulating intake and ensuring adequate volume replacement. Where opportunities allow (...) Factors influencing the restoration of fluid and electrolyte balance after exercise in the heat. Maintenance of fluid balance is a major concern for all athletes competing in events held in hot climates. This paper reviews recent work relating to optimisation of fluid replacement after sweat loss induced by exercising in the heat. Data are taken from studies undertaken in our laboratory. Issues investigated were drink composition, volume consumed, effects of consuming food with a drink, effects

1997 British Journal of Sports Medicine

4237. Nebulized levalbuterol or albuterol for lowering serum potassium

of 7.3. While starting Ca gluconate, glucose/insulin, nebulized albuterol and kayexelate you wonder if substitution of levalbuterol for albuterol would have the same lowering effect on serum potassium and have fewer side effects. Search Strategy Medline 1966 - October 2004 using the OVID interface. [levalbuterol.mp or exp Albuterol/ OR (albuterol or salbutamol).mp OR exp bronchodilator agents/ OR exp adrenergic beta-agonists/ OR beta-agonists.mp] AND [exp stereoisomerism/ OR enantiomers.mp (...) Nebulized levalbuterol or albuterol for lowering serum potassium BestBets: Nebulized levalbuterol or albuterol for lowering serum potassium Nebulized levalbuterol or albuterol for lowering serum potassium Report By: Herald Ostovar, MD - Senior EM Resident Search checked by Dr Jeffrey Jones and Dr Michael Brown - Research Director and Director of the Emergency Medicine Residency program respectively Institution: Emergency Medicine Residency, Grand Rapids MERC/ Michigan State University Current

2005 BestBETS

4238. Is there any evidence that lisinopril causes elevated potassium levels compared to other ACE inhibitors

does not usually occur in renocompetent patients, but those who have renal insufficiency or diabetes. Patients who are taking potassium, salt substitutes, potassium-sparing diuretics, beta blockers, and NSAIDs are susceptible. Most clinicians discontinue potassium and potassium-sparing diuretics when starting patients on ACE inhibitor therapy. Potassium levels should be monitored carefully in patients at risk. Up to 5 percent of patients experience serum potassium levels greater than 5.7 mEq per L (...) Is there any evidence that lisinopril causes elevated potassium levels compared to other ACE inhibitors Is there any evidence that lisinopril causes elevated potassium levels compared to other ACE inhibitors - Trip Database or use your Google+ account Find evidence fast ALL of these words: Title only Anywhere in the document ANY of these words: Title only Anywhere in the document This EXACT phrase: Title only Anywhere in the document EXCLUDING words: Title only Anywhere in the document

2008 TRIP Answers

4239. Potassium

Potassium Potassium Produced by In partnership with User Top Links Menu Search User Top Links Search Potassium Test Also Known As K Formal Name Potassium This article was last reviewed on 29 March 2019. This article was last modified on 1 April 2019. At a Glance Why Get Tested? To determine if the concentration of potassium in your blood is within normal range. When To Get Tested? Blood potassium concentrations are frequently measured as part of routine health screening and in the clinical (...) on reference ranges, please read . What is being tested? Potassium is present in all body fluids, but most potassium is within your cells. Only a very small amount of potassium is contained within the or component of the blood. In health, the amount of potassium within serum is tightly controlled, however, many illnesses / drugs can cause concentrations of potassium to become too high or too low. An abnormal concentration can alter the function of the nerves and muscles including those of the heart.I

2004 Lab Tests Online UK

4240. Does Potassium Bicarbonate Improve the Effect of Dietary Protein on Bone and Muscle?

during the study. Subjects will not be allowed to take their own calcium or vitamin D supplements from one week before their screening visit through the end of the study. They must also agree not to ingest bicarbonate- or potassium-rich products such as selected antacids and salt substitutes during the study. They must also agree not to consume alcohol during the study. Exclusion Criteria: Medications Oral glucocorticoid use for > 10 days in the last 3 months Estrogen, raloxifene, or calcitonin use (...) Does Potassium Bicarbonate Improve the Effect of Dietary Protein on Bone and Muscle? Does Potassium Bicarbonate Improve the Effect of Dietary Protein on Bone and Muscle? - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before

2008 Clinical Trials

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