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Postpartum Endometritis

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161. Pedometers for the Enhancement of Post Cesarean Mobility

Measures : Number of participants with a postpartum complication composite [ Time Frame: 48 hours ] Composite of postpartum complications, including infectious (endometritis, wound), blood product transfusion Number of analgesic doses [ Time Frame: 48 hours ] Number of doses of analgesics consumed by patient Length of hospitalization [ Time Frame: From 72 hours to one week ] Duration of postpartum hospitalization Number of thromboembolic events [ Time Frame: Six weeks ] Thromboembolic events during (...) the post partum period, including deep vein thrombosis and pulmonary emboli Eligibility Criteria Go to Information from the National Library of Medicine Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Layout table for eligibility information Ages

2018 Clinical Trials

162. Librata Endometrial Ablation Device Treatment to Reduce Menstrual Blood Loss

of the operative visit Presence of an implanted contraceptive device (e.g. Essure or Adiana). Subject not currently on hormonal birth control therapy and unwilling to use a non-hormonal birth control post-ablation Subject wanting concomitant hysteroscopic sterilization Subject who is within 6-weeks post-partum Any general health condition which, in the opinion of the Investigator, could represent an increased risk for the subject Any subject who is currently participating in the primary endpoint phase (...) . Librata Endometrial Ablation Device Treatment to Reduce Menstrual Blood Loss (LEADER) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT03725306 Recruitment Status : Not yet recruiting First Posted : October 31, 2018 Last

2018 Clinical Trials

163. Point of Care Ultrasound Screening for Abnormal Fetal Growth During Routine Antenatal Visits

or > 90th percentile Maternal and neonatal outcomes [ Time Frame: Up to 2 years ] To compare maternal (emergency CD for non reassuring FHT, chorioamnionitis/post partum endometritis, wound infection/hematoma/seroma, PRBC transfusion, admission to the ICU, DVT/PE, maternal death) and perinatal (fetal death, neonatal death, Apgar score >< 4 at 5 min, neonatal seizures, umbilical-artery blood pH of 7.05 or less with a base deficit of 12 mmol per liter or more, intubation at delivery, neonatal (...) Posted : October 22, 2018 Last Update Posted : March 6, 2019 See Sponsor: The University of Texas Medical Branch, Galveston Information provided by (Responsible Party): The University of Texas Medical Branch, Galveston Study Details Study Description Go to Brief Summary: Abdominal circumference (AC) in the fetus is the single most useful indicator of fetal growth abnormalities. Measurement of AC as well as DVP do not require extensive training. Our objective is to evaluate if introduction of bedside

2018 Clinical Trials

164. Endometrial Stem Cells in Farm Animals: Potential Role in Uterine Physiology and Pathology Full Text available with Trip Pro

on the bovine species. In bovines, eMSCs have been identified during the phases of the estrous cycle, during which their functionality and the presence of eMSC-specific markers has been shown to change. Moreover, postpartum inflammation related to endometritis affects the presence and functionality of eMSCs, and prostaglandin E2 (PGE₂) may be the mediator of such changes. We demonstrated that exposure to PGE₂ in vitro modifies the transcriptomic profile of eMSCs, showing its potential role in the fate (...) of stem cell activation, migration, and homing during pathological uterine inflammation in endometritis and in healthy puerperal endometrium. Farm animal research on eMSCs can be of great value in translational research for certain uterine pathologies and for immunomodulation of local responses to pathogens, hormones, and other substances. Further research is necessary in areas such as in vivo location of the niches and their immunomodulatory and anti-infective properties.

2018 Bioengineering

165. Prophylactic antibiotics for the prevention of infection following operative vaginal delivery (ANODE): study protocol for a randomised controlled trial Full Text available with Trip Pro

describes a multicentre, randomised, blinded, placebo-controlled trial aiming to recruit 3424 participants from over 20 hospital sites in the UK. Women who have undergone an operative vaginal delivery at 36+0 weeks or greater gestation with no indication for ongoing antibiotics in the postpartum period and no contra-indications to prophylactic co-amoxiclav, will be randomised to receive a single intravenous dose of co-amoxiclav or placebo. The primary outcome will be confirmed or suspected maternal (...) infection within 6 weeks of delivery, as defined by one of (a) a new prescription of antibiotics for presumed perineal wound-related infection, endometritis or uterine infection, urinary tract infection with systemic features or other systemic infection, (b) systemic infection confirmed with a culture or (c) endometritis as defined by the US Centers for Disease Control and Prevention. Outcome information will be collected by a single telephone interview and questionnaire, with clinical data collected

2018 Trials

166. Trichomonas vaginalis Transports Virulent Mycoplasma hominis and Transmits the Infection to Human Cells after Metronidazole Treatment: A Potential Role in Bacterial Invasion of Fetal Membranes and Amniotic Fluid Full Text available with Trip Pro

Trichomonas vaginalis Transports Virulent Mycoplasma hominis and Transmits the Infection to Human Cells after Metronidazole Treatment: A Potential Role in Bacterial Invasion of Fetal Membranes and Amniotic Fluid Mycoplasma hominis is considered an opportunistic pathogen able to colonize the lower urogenital tract; in females the infection is associated with severe pregnancy and postpartum complications, including abortion, endometritis, preterm delivery, and low birth weight. Molecular

2018 Journal of pregnancy

167. Prevalence and Clinical Significance of Streptococcus dysgalactiae subspecies equisimilis (Groups C or G Streptococci) Colonization in Pregnant Women: A Retrospective Cohort Study Full Text available with Trip Pro

taken at 35-37 weeks of pregnancy were analyzed at Tampere University Hospital, Finland, between 2012 and 2014. From this laboratory data, all Streptococcus G or C-positive cultures were included to study maternal and neonatal infectious morbidity after delivery. This study population was compared to women with a positive Streptococcus B culture and to women with a negative culture.The prevalence of Streptococcus G or C colonization was 2.9%. Significantly more postpartum endometritis was found (...) in this study group. No association was found between colonization and neonatal bacteremia.Streptococcus G or C colonization is associated with postpartum endometritis. More research is needed to clarify if antibiotic prophylaxis is reasonable for this group during delivery.

2018 Infectious diseases in obstetrics and gynecology

168. Comparison of Insulin Alone to Insulin With Metformin to Treat Gestational Diabetes Mellitus

disorder of pregnancy [ Time Frame: from enrollment through study completion (30 days after delivery) ] gestational HTN, superimposed pre-eclampsia, pre-eclampsia-eclampsia Incidence of composite of adverse maternal outcomes [ Time Frame: from enrollment through study completion (30 days after delivery) ] death, ICU admission, postpartum hemorrhage, blood transfusion, organ failure, chorioamnionitis/endometritis Breast feeding status [ Time Frame: Will be recorded at the time of hospital discharge (...) studies before adding more. Comparison of Insulin Alone to Insulin With Metformin to Treat Gestational Diabetes Mellitus The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT03651531 Recruitment Status : Recruiting First Posted

2018 Clinical Trials

169. Comparison of Misoprostol Ripening Efficacy With Dilapan

or Misoprostol for cervical ripening Percentage of women who developed endometritis within 14 days of intervention [ Time Frame: From delivery until two weeks after discharge (approximately up to 3 weeks) ] This is to measure the safety of either Dilapan or Misoprostol for cervical ripening Percentage of women who developed postpartum hemorrhage [ Time Frame: From delivery until two weeks after discharge (approximately up to 3 weeks) ] This is to measure the safety of either Dilapan or Misoprostol (...) With Dilapan (COMRED) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT03670836 Recruitment Status : Recruiting First Posted : September 14, 2018 Last Update Posted : January 14, 2019 See Sponsor: Columbia University Collaborator

2018 Clinical Trials

170. Association of chorioamnionitis and its duration with adverse maternal outcomes by mode of delivery: a cohort study. (Abstract)

the duration of chorioamnionitis estimated from intrapartum antibiotic use, with adverse maternal outcomes was analysed using logistic regression with generalised estimating equations, adjusting for age, parity, race, pregestational diabetes, chronic hypertension, gestational age at delivery, study site and delivery year. Analyses were stratified by vaginal versus caesarean delivery.The composite adverse maternal outcome included: postpartum transfusion, endometritis, wound/perineal infection/separation (...) , venous thromboembolism, hysterectomy, admission to intensive care unit and/or death.Chorioamnionitis was associated with higher odds of the composite adverse maternal outcome with caesarean delivery (adjusted odds ratio 2.31; 95% CI 1.97-2.71); and the association persisted regardless of whether a woman had a trial of labour, preterm delivery or maternal group B streptococcus colonisation. The most common adverse outcomes after caesarean section were postpartum transfusion (56.0%) and wound/perineal

2018 BJOG

171. Antibiotics During Intrauterine Balloon Tamponade Placement

Center Information provided by (Responsible Party): Kimberly Gregory, Cedars-Sinai Medical Center Study Details Study Description Go to Brief Summary: The goal of this study is to identify whether antibiotics given at the time of placement of an intrauterine balloon tamponade (IBT) will result in reduction of the risk of endometritis. The investigators hypothesize that antibiotics given at the time of intrauterine balloon tamponade will reduce the likelihood of postpartum endometritis. Condition (...) or disease Intervention/treatment Phase Obstetric Complication Postpartum Hemorrhage Postpartum Endometritis Drug: CeFAZolin 1000 MG Drug: Clindamycin 900 MG in 6 ML Injection Phase 4 Detailed Description: The investigators will perform a randomized, controlled trial of women who have had a postpartum hemorrhage and received an intrauterine balloon tamponade. Patients who are candidates for study enrollment will be identified on Labor & Delivery or in the Maternal-Fetal Care Unit. Patients who give

2018 Clinical Trials

172. Routine Cervical Dilatation at the Non-labour Caesarean Section and Its Influence on Postoperative Pain

defined to reduce the risk of peri/post-operative morbidity. The digital dilatation of cervix during elective caesarean section has still been a concern when evaluating this issue. This procedure is supposed to help the drainage of blood and lochia postpartum, thus reducing infection or the risk of postpartum haemorrhage (PPH). However, on the contrary, this mechanical manipulation may also result in contamination by a vaginal micro-organism and increase the risk of infections or cervical trauma (...) in obstetrics. With the recent increase in the rate of this procedure, it is wise to understand and implement the optimal surgical technique. Therefore, different operational methods have been defined to reduce the risk of peri/post-operative morbidity. The digital dilatation of cervix during elective caesarean section has still been a concern when evaluating this issue. This procedure is supposed to help the drainage of blood and lochia postpartum, thus reducing infection or the risk of postpartum

2018 Clinical Trials

173. Effects of ACS in Twin With LPB: Study Protocol for a RCT

death Secondary Outcome Measures : Maternal complication [ Time Frame: 72 hours after birth ] Chorioamnionitis and Postpartum endometritis Respiratory distress syndrome [ Time Frame: 72 hours after birth ] Presence of clinical signs of respiratory distress (tachypnea, retractions, flaring, grunting, or cyanosis), with a requirement for supplemental oxygen with a fraction of inspired oxygen of more than 0.21 and a chest radiograph showing hypoaeration and reticulogranular infiltrates Transient (...) Protocol for a RCT The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT03547791 Recruitment Status : Recruiting First Posted : June 6, 2018 Last Update Posted : June 6, 2018 See Sponsor: Seoul National University Hospital

2018 Clinical Trials

174. Effect of Vaginal Douching With Betadine Before CS for Prevention of Post Operative Infections

: Betadine douches subjects received a vaginal preparation with povidone-iodine solution immediately prior to caesarean delivery Behavioral: Betadine douches subjects received a vaginal preparation with povidone-iodine solution immediately prior to caesarean delivery No Intervention: Non betadine douches subjects didnot received a vaginal preparation prior to caesarean delivery Outcome Measures Go to Primary Outcome Measures : Postpartum endometritis [ Time Frame: 6 weeks after Cesarean section (...) Effect of Vaginal Douching With Betadine Before CS for Prevention of Post Operative Infections Effect of Vaginal Douching With Betadine Before CS for Prevention of Post Operative Infections - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one

2018 Clinical Trials

175. The effect of endometrial thickness on pregnancy outcome in patients with Asherman’s syndrome post-hysteroscopic adhesiolysis Full Text available with Trip Pro

that included 41 women who attended Women's Specialized Hospital, King Fahad Medical City from December 2008 to December 2015, presented with a history of infertility or recurrent pregnancy loss, and were diagnosed with intrauterine adhesions and treated by hysteroscopic adhesiolysis. To analyze the causative factors of AS, history of curettage, miscarriage, postpartum hemorrhage, hysteroscopy, endometritis, and any uterine surgery were recorded. Patients were followed up for 2 years to account (...) The effect of endometrial thickness on pregnancy outcome in patients with Asherman’s syndrome post-hysteroscopic adhesiolysis Hysteroscopic adhesiolysis anatomically restores the uterine cavity in cases of Asherman's syndrome (AS); however, the extent of endometrial fibrosis could determine the pregnancy outcome.To determine whether endometrial thickness could influence pregnancy outcome of hysteroscopic adhesiolysis in women with a history of AS.This was a retrospective cohort study

2018 International journal of women's health

176. Preoperative Application of Chlorhexidine to Reduce Infection With Cesarean Section After Labor

% chlorhexidine gluconate) in addition to routine IV antibiotics. Drug: 2% chlorhexidine gluconate cloth applied to their abdomen Other Name: 2% Chloraprep solution Outcome Measures Go to Primary Outcome Measures : Rate of surgical site infection [ Time Frame: up to 6 weeks postpartum ] Surgical site infection will be a composite of wound infection and postpartum endometritis. Endometritis is defined as postoperative fever of 100.4 °F or more occurring 24 hours after delivery associated with uterine (...) : Recruiting First Posted : February 6, 2018 Last Update Posted : February 12, 2019 See Sponsor: Angela Bianco Collaborator: Stryker Nordic Information provided by (Responsible Party): Angela Bianco, Icahn School of Medicine at Mount Sinai Study Details Study Description Go to Brief Summary: Surgical site infections (SSI) are the second most common cause of nosocomial infections accounting for 15% of all nosocomial infections among hospitalized patients and 38% of nosocomial infections in surgical patients

2018 Clinical Trials

177. Low Implanted Second Trimester Placenta and Placenta Previa

Placenta and Placenta Previa The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT03431116 Recruitment Status : Completed First Posted : February 13, 2018 Last Update Posted : February 13, 2018 Sponsor: Assiut University Information provided by (Responsible Party): Mohammed Khairy Ali, Assiut University (...) to. Although various studies have tried to address risk factors associated with Placenta Previa development, the etiology of placenta previa still remains obscure. Several risk actors have been identified as strong contributors to placenta previa development. It is also a significant contributor to severe postpartum hemorrhage.Risk factors include; history of previous cesarean section, advanced maternal age, history of previous abortions, high parity and substance abuse during pregnancy (cigarette smoking

2018 Clinical Trials

178. Mechanical Dilatation of the Cervix at Elective Caesarean Section to Reduce Post-Operative Blood Loss

for national guideline development. Some obstetricians believe that the cervix of women at non-labor cesarean section is undilated and might cause obstruction of blood or lochia drainage, leading to postpartum hemorrhage and endometritis from the collection of lochia or debris. Dilatation of the cervix helps with the drainage of blood during postpartum, reducing intrauterine infection or the risk of postpartum hemorrhage. To avoid this problem, some obstetricians routinely dilate the cervix from above (...) : No Criteria Inclusion Criteria: pregnant women with a single term fetus >37 weeks of gestational age, with American Society of Anesthesiology (ASA) physical status I or II undergoing Elective Cs (primary or repeated CS). Age group 20 - 35 years old Exclusion Criteria: Chorioamnionitis. Placenta previa. Multiple gestations. Preeclampsia. Macrosomia. Hydramnios. Uterine leiomyomata. Anemia. Previous cervical surgery. Previous post-partum hemorrhage. Bleeding tendency. Hypertension. Diabetes mellitus

2018 Clinical Trials

179. Digital Cervical and Cesarean Section

disease. Blood transfusion during surgery or before it. History of wound infection or endometritis . Ante partum hemorrhage. History of long corticosteroid use. Women refuse to participate in the study. Suspected clinical evidence of infection. anemic women Multiple pregnancy Preterm births Rupture of membranes or chorioamnionitis Women who use antibiotics during the last 24 hours due to any infection but not prophylactic antibiotic during caesarian section Emergency caesarean section Contacts (...) of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT03392077 Recruitment Status : Recruiting First Posted : January 5, 2018 Last Update Posted : January 5, 2018 See Sponsor: Assiut University Information provided by (Responsible Party): Mohammed Khairy Ali, Assiut

2018 Clinical Trials

180. HIV, viral hepatitis and STIs - a guide for primary care

Menadue; Anne Mijch; Paul Nisselle; David Orth; John Patten; Jeffrey Post; David Puls; Jacqui Richmond; Gary Rogers; Norman Roth; Joe Sasadeusz; Moira Sim; Jenean Spencer; Simone Strasser; Ingrid van Beek; Jack Wallace; Jeff Ward; Steve Wesselingh; Jon Willis. Additional sub-editors and proof-readers Tim Badgery-Parker; Robert Booker; Wendy Bryant; Levinia Crooks; Vicky Fisher (2004 Edition); Carla Gorton (2004 Edition); Megan Nicholson; Susie Prest; Vanessa Sparrow; Gary Wright; Helen Young; Adrian

2014 Clinical Practice Guidelines Portal

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