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Postpartum Endometritis

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41. Endometritis (Overview)

as acute versus chronic. Acute endometritis is characterized by the presence of neutrophils within the endometrial glands. Chronic endometritis is characterized by the presence of plasma cells and lymphocytes within the endometrial stroma. In the nonobstetric population, pelvic inflammatory disease and invasive gynecologic procedures are the most common precursors to acute endometritis. In the obstetric population, postpartum infection is the most common predecessor. Chronic endometritis (...) is not higher in users of modern intrauterine devices than in non-users. [ , , ] Previous Next: Etiology Endometritis is a polymicrobial disease involving, on average, 2-3 organisms. In most cases, it arises from an ascending infection from organisms found in the normal indigenous vaginal flora. Commonly isolated organisms include Ureaplasma urealyticum, , Gardnerella vaginalis, Bacteroides bivius, and . has been associated with late-onset postpartum endometritis. is identified in up to 25% of women who

2014 eMedicine.com

42. Endometritis (Treatment)

, Bavaro MF, You WB. Postpartum herpes simplex virus endometritis and disseminated infection in both mother and neonate. Obstet Gynecol . 2012 Aug. 120(2 Pt 2):471-3. . Onuigbo W, Esimai B, Nwaekpe C, Chijioke G. Tubercular endometritis detected through Pap smear campaign in Enugu, Nigeria. Pan Afr Med J . 2012. 11:47. . Saracoglu OF, Mungan T, Tanzer F. Pelvic tuberculosis. Int J Gynaecol Obstet . 1992 Feb. 37(2):115-20. . Ness RB, Soper DE, Holley RL, Peipert J, Randall H, Sweet RL, et al. Douching (...) -stage vs first-stage caesarean delivery: Comparison of maternal and perinatal outcomes. J Obstet Gynaecol . 2014 Oct. 34(7):598-604. . Haggerty CL, Hillier SL, Bass DC, Ness RB. Bacterial vaginosis and anaerobic bacteria are associated with endometritis. Clin Infect Dis . 2004 Oct 1. 39(7):990-5. . Jacobsson B, Pernevi P, Chidekel L, Jörgen Platz-Christensen J. Bacterial vaginosis in early pregnancy may predispose for preterm birth and postpartum endometritis. Acta Obstet Gynecol Scand . 2002 Nov

2014 eMedicine.com

43. Endometritis (Follow-up)

, Bavaro MF, You WB. Postpartum herpes simplex virus endometritis and disseminated infection in both mother and neonate. Obstet Gynecol . 2012 Aug. 120(2 Pt 2):471-3. . Onuigbo W, Esimai B, Nwaekpe C, Chijioke G. Tubercular endometritis detected through Pap smear campaign in Enugu, Nigeria. Pan Afr Med J . 2012. 11:47. . Saracoglu OF, Mungan T, Tanzer F. Pelvic tuberculosis. Int J Gynaecol Obstet . 1992 Feb. 37(2):115-20. . Ness RB, Soper DE, Holley RL, Peipert J, Randall H, Sweet RL, et al. Douching (...) -stage vs first-stage caesarean delivery: Comparison of maternal and perinatal outcomes. J Obstet Gynaecol . 2014 Oct. 34(7):598-604. . Haggerty CL, Hillier SL, Bass DC, Ness RB. Bacterial vaginosis and anaerobic bacteria are associated with endometritis. Clin Infect Dis . 2004 Oct 1. 39(7):990-5. . Jacobsson B, Pernevi P, Chidekel L, Jörgen Platz-Christensen J. Bacterial vaginosis in early pregnancy may predispose for preterm birth and postpartum endometritis. Acta Obstet Gynecol Scand . 2002 Nov

2014 eMedicine.com

44. Endometritis (Treatment)

, Bavaro MF, You WB. Postpartum herpes simplex virus endometritis and disseminated infection in both mother and neonate. Obstet Gynecol . 2012 Aug. 120(2 Pt 2):471-3. . Onuigbo W, Esimai B, Nwaekpe C, Chijioke G. Tubercular endometritis detected through Pap smear campaign in Enugu, Nigeria. Pan Afr Med J . 2012. 11:47. . Saracoglu OF, Mungan T, Tanzer F. Pelvic tuberculosis. Int J Gynaecol Obstet . 1992 Feb. 37(2):115-20. . Ness RB, Soper DE, Holley RL, Peipert J, Randall H, Sweet RL, et al. Douching (...) -stage vs first-stage caesarean delivery: Comparison of maternal and perinatal outcomes. J Obstet Gynaecol . 2014 Oct. 34(7):598-604. . Haggerty CL, Hillier SL, Bass DC, Ness RB. Bacterial vaginosis and anaerobic bacteria are associated with endometritis. Clin Infect Dis . 2004 Oct 1. 39(7):990-5. . Jacobsson B, Pernevi P, Chidekel L, Jörgen Platz-Christensen J. Bacterial vaginosis in early pregnancy may predispose for preterm birth and postpartum endometritis. Acta Obstet Gynecol Scand . 2002 Nov

2014 eMedicine Pediatrics

45. Endometritis (Overview)

as acute versus chronic. Acute endometritis is characterized by the presence of neutrophils within the endometrial glands. Chronic endometritis is characterized by the presence of plasma cells and lymphocytes within the endometrial stroma. In the nonobstetric population, pelvic inflammatory disease and invasive gynecologic procedures are the most common precursors to acute endometritis. In the obstetric population, postpartum infection is the most common predecessor. Chronic endometritis (...) is not higher in users of modern intrauterine devices than in non-users. [ , , ] Previous Next: Etiology Endometritis is a polymicrobial disease involving, on average, 2-3 organisms. In most cases, it arises from an ascending infection from organisms found in the normal indigenous vaginal flora. Commonly isolated organisms include Ureaplasma urealyticum, , Gardnerella vaginalis, Bacteroides bivius, and . has been associated with late-onset postpartum endometritis. is identified in up to 25% of women who

2014 eMedicine Pediatrics

46. Endometritis (Follow-up)

, Bavaro MF, You WB. Postpartum herpes simplex virus endometritis and disseminated infection in both mother and neonate. Obstet Gynecol . 2012 Aug. 120(2 Pt 2):471-3. . Onuigbo W, Esimai B, Nwaekpe C, Chijioke G. Tubercular endometritis detected through Pap smear campaign in Enugu, Nigeria. Pan Afr Med J . 2012. 11:47. . Saracoglu OF, Mungan T, Tanzer F. Pelvic tuberculosis. Int J Gynaecol Obstet . 1992 Feb. 37(2):115-20. . Ness RB, Soper DE, Holley RL, Peipert J, Randall H, Sweet RL, et al. Douching (...) -stage vs first-stage caesarean delivery: Comparison of maternal and perinatal outcomes. J Obstet Gynaecol . 2014 Oct. 34(7):598-604. . Haggerty CL, Hillier SL, Bass DC, Ness RB. Bacterial vaginosis and anaerobic bacteria are associated with endometritis. Clin Infect Dis . 2004 Oct 1. 39(7):990-5. . Jacobsson B, Pernevi P, Chidekel L, Jörgen Platz-Christensen J. Bacterial vaginosis in early pregnancy may predispose for preterm birth and postpartum endometritis. Acta Obstet Gynecol Scand . 2002 Nov

2014 eMedicine Pediatrics

47. Therapy of bovine endometritis with prostaglandin F2α: a meta-analysis. (PubMed)

Therapy of bovine endometritis with prostaglandin F2α: a meta-analysis. The objective of the conducted meta-analysis was to assess the efficacy of the treatment of bovine endometritis with PGF(2α) by statistical means. Postpartum uterine infections have a high prevalence and a very negative effect on reproductive performance in dairy cattle. Because of a wide discordance between research results, a meta-analysis of the efficacy of the treatment of bovine endometritis with PGF(2α) was conducted (...) ). Estimated effect sizes of PGF(2α) were calculated on calving to first service and calving to conception interval. Prostaglandin F(2α) treatment of cows with chronic endometritis had a negative effect on both reproductive performance parameters. Heterogeneity was substantial for calving to first service and calving to conception interval [I(2) (measure of variation beyond chance)=100 and 87%, respectively]; therefore, random-effects models were used. Sensitivity analysis as well as subgroup analysis

2013 Journal of dairy science

48. Effects of 1 or 2 treatments with prostaglandin F₂α on subclinical endometritis and fertility in lactating dairy cows inseminated by timed artificial insemination. (PubMed)

Effects of 1 or 2 treatments with prostaglandin F₂α on subclinical endometritis and fertility in lactating dairy cows inseminated by timed artificial insemination. The objectives of the current study were to investigate the efficacy of PGF₂α as a therapy to reduce the prevalence of subclinical endometritis and improve pregnancy per artificial insemination (P/AI) in cows subjected to a timed artificial insemination (AI) program. A total of 1,342 lactating Holstein dairy cows were allocated (...) ). Subclinical endometritis was defined by the presence of ≥ 5% PMNL. Vaginal discharge score was evaluated at 25 ± 3 DIM and used to define the prevalence of purulent vaginal discharge. Body condition score was assessed at 25 ± 3 DIM. Pregnancy was diagnosed 32 d after AI and reconfirmed 28 d later. At 32 ± 3 DIM, the prevalence of subclinical endometritis was reduced by treatment with PGF₂α at 25 ± 3 DIM in 2PGF (control=23.5% vs. 1PGF=28.3% vs. 2PGF=16.7%); however, this benefit disappeared at 46 ± 3 DIM

2013 Journal of dairy science

49. Does vaginal preparation with povidone-iodine prior to caesarean delivery reduce the risk of endometritis? A randomized controlled trial. (PubMed)

Does vaginal preparation with povidone-iodine prior to caesarean delivery reduce the risk of endometritis? A randomized controlled trial. The purpose of the present study was to determine whether the vaginal preparation with povidone-iodine prior to caesarean delivery decreased the incidence of postpartum endometritis.The present study was a prospective randomized controlled trial in which subjects received a vaginal preparation with povidone-iodine solution immediately prior to caesarean (...) delivery or received no vaginal preparation. The primary outcome measure was the rate of postpartum endometritis.A significant decrease in post-caesarean endometritis was noted in the group that received the povidone-iodine vaginal preparation (n = 334) compared with the control group (n = 336) [6.9 vs. 11.6%; RR = 1.69; 95% CI = 1.03-2.76]. No statistically significant differences in the incidence of endometritis were noted between the experimental and control groups among women who were not in labor

2012 The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians

50. Endometritis Antibiotic Management

Endometritis Antibiotic Management Endometritis Antibiotic Management Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Endometritis (...) Antibiotic Management Endometritis Antibiotic Management Aka: Endometritis Antibiotic Management , Chorioamnionitis Antibiotic Management From Related Chapters II. Management: Antibiotics Common Protocol 2 g IV every 6 hours Gentamycin 1.5 mg/kg (Maximum 80-100 mg) q8 hours Adjust dosing per kinetics if >1-2 days use Alternative Medications Mezlocillin 3 grams IV every 4 hours 3 grams IV every 4 hours 3.1 grams IV every 6 hours 3 grams IV every 4-6 hours III. Management: Antibiotics added anaerobic

2015 FP Notebook

51. Endometritis

, Endomyometritis From Related Chapters II. Causes Postpartum Endometritis Early Postpartum (<48 hours) after Late Postpartum (48 hours - 6 weeks) after Uterine instrumentation III. Pathophysiology of the M. hominis IV. Symptoms Lower abdominal cramps Foul and V. Signs Lower abdominal tenderness and muscle spasm Cervical motion tenderness VI. Labs and culture of cervical discharge swab VII. Management Inpatient (Indicated in most cases) Option 1 OR OR Imipenem OR AND Option 2 AND OR OR Gentamycin Outpatient (...) involving the endometrium. It may extend to the myometrium and parametrial tissues. Definition (NCI) An acute or chronic, usually bacterial infectious process affecting the endometrium. It may extend to the myometrium and parametrial tissues. Symptoms include lower abdominal pain, vaginal discharge, and vaginal bleeding. Definition (MSH) Inflammation of the ENDOMETRIUM, usually caused by intrauterine infections. Endometritis is the most common cause of postpartum fever. Concepts Disease or Syndrome

2015 FP Notebook

52. A postpartum haemorrhage package with condom uterine balloon tamponade: a prospective multi-centre case series in Kenya, Sierra Leone, Senegal, and Nepal. (Full text)

UBT-associated complication (postpartum endometritis) was identified and two improvised UBTs were placed in women with a ruptured uterus.These pilot data suggest that the ESM-UBT package is a clinically promising and safe method to arrest uncontrolled postpartum haemorrhage and save women's lives. The UBT was successfully placed by all levels of facility-based providers. Future studies are needed to further evaluate the effectiveness of ESM-UBT in low-resource settings.Evidence for ESM-UBT (...) A postpartum haemorrhage package with condom uterine balloon tamponade: a prospective multi-centre case series in Kenya, Sierra Leone, Senegal, and Nepal. To evaluate the effectiveness and safety of an ultra-low-cost uterine balloon tamponade package (ESM-UBT™) for facility-based management of uncontrolled postpartum haemorrhage (PPH) in Kenya, Sierra Leone, Senegal, and Nepal.Prospective multi-centre case series.Facilities in resource-scarce areas of Kenya, Sierra Leone, Nepal

2015 BJOG PubMed

53. Severe Secondary Postpartum Hemorrhage: A Historical Cohort. (PubMed)

Severe Secondary Postpartum Hemorrhage: A Historical Cohort. The principal objective of our study was to describe the frequency of severe secondary postpartum hemorrhages (PPH). Our secondary objectives were to describe the different causes of PPH and to assess if the PPH etiologies varied by parity.This is a historical cohort study covering the period from January 1, 2004, through February 13, 2013, in a level III maternity ward. Women were eligible if they were treated for severe secondary (...) PPH during their postpartum hospitalization or were admitted for it after discharge but before the 42nd day postpartum, regardless of the type of delivery. Women were excluded if they gave birth before 22 weeks of gestation or if they had experienced only an immediate PPH (≤ 24 hours after delivery). Eligible patients were identified by the hospital's administrative software. Primiparas and multiparas were compared with Student's t test and a chi-squared or Fisher's exact test.The incidence

2015 Birth

54. Determinants of health-related quality of life in the postpartum period after obstetric complications. (PubMed)

, congenital anomaly, urinary tract infection, thromboembolic event or endometritis. MCS was influenced only mildly by these parameters.IUGR and hypertensive disorders lead to lower HRQoL scores postpartum than PPH. In a heterogeneous obstetric population, only mode of delivery by cesarean section has a profound, negative impact, on physical HRQoL (PCS). No profound impacts on MCS were detected.Copyright © 2014 Elsevier Ireland Ltd. All rights reserved. (...) Determinants of health-related quality of life in the postpartum period after obstetric complications. To determine the influence of socio-demographic, clinical parameters and obstetric complications on postpartum health-related quality of life (HRQoL).We used data of three randomized controlled trials to investigate HRQoL determinants in women after an obstetric complication. The DIGITAT and HYPITAT trials compared induction of labor and expectant management in women with intra-uterine growth

2015 European journal of obstetrics, gynecology, and reproductive biology

55. Inducing ovulation early postpartum influences uterine health and fertility in dairy cows. (PubMed)

Inducing ovulation early postpartum influences uterine health and fertility in dairy cows. The objective of the current study was to evaluate the effect of GnRH early postpartum on induction of ovulation, uterine health, and fertility in dairy cows. Holstein cows without a corpus luteum (CL) at 17 ± 3 DIM were assigned randomly to receive i.m. GnRH (n = 245) at 17 ± 3 and 20 ± 3 DIM or remain as controls (n = 245). Ovaries were scanned by ultrasonography twice weekly totaling 4 examinations (...) . Ovulation was characterized by the appearance of a CL ≥ 20 mm at any ultrasound or CL <20mm in 2 consecutive examinations. Clinical and cytological endometritis were diagnosed at 35 DIM. Compared with control, GnRH increased ovulation up to 3.5d after the last treatment (78.7 vs. 45.0%) and did not affect the prevalence of clinical endometritis (23.9 vs. 18.6%) or cytological endometritis (30.9 vs. 32.8%). Prevalence of clinical endometritis increased in cows that had calving problems (32.6 vs. 15.9

2014 Journal of dairy science

56. Extensive pulmonary involvement with raltegravir-induced DRESS syndrome in a postpartum woman with HIV (Full text)

Extensive pulmonary involvement with raltegravir-induced DRESS syndrome in a postpartum woman with HIV An 18-year-old postpartum woman with HIV, on lamivudine-zidovudine, lopinavir-ritonavir and raltegravir, presented with a 1-week history of rash and fevers. Initially admitted to obstetrics and gynaecology service for treatment of possible endometritis, she was transferred to the HIV medicine service for high fever, respiratory distress, hypotension and tachycardia. On admission, she

2014 BMJ case reports PubMed

57. Recurrent secondary postpartum hemorrhages due to placental site vessel subinvolution and local uterine tissue coagulopathy. (Full text)

are already discharged home. The causes of this pathology are severe inflammation (endometritis), inherited coagulation disorders, consumptive coagulopathy, and retained products of conceptions. Others are of rare occurrence, such as vessel subinvolution (VSI) of the placental implantation site, uterine artery pseudoaneurysm, or trauma.We present a rare form of recurrent secondary postpartum hemorrhage in a woman after uncomplicated cesarean delivery, with review of the literature linked to the management (...) Recurrent secondary postpartum hemorrhages due to placental site vessel subinvolution and local uterine tissue coagulopathy. Postpartum hemorrhage (PPH) represents a serious problem for women and obstetricians. Because of its association with hemorrhagic shock and predisposition to disseminated coagulopathy, it is a leading cause of maternal deaths worldwide. Furthermore, the jeopardy of PPH is rising with the secondary form of PPH occurring between 24 hours and 6 weeks postpartum, when women

2014 BMC Pregnancy and Childbirth PubMed

58. Intrauterine Tamponade With a Belfort-Dildy Balloon in the Treatment of Severe Immediate Postpartum Hemorrhage

[ Time Frame: 8 days ] Assessed by : Proportion of women with a temperature >38°5C during postpartum hospitalization other Genital tract infection [ Time Frame: 8 days ] Assessed by : Proportion of women with endometritis during postpartum hospitalization. other Genital tract infection [ Time Frame: 6 weeks ] Assessed by : • Proportion of women who had endometritis at the 6 weeks postpartum visit. Other markers of severe hemorrhage [ Time Frame: 8 days ] Number of women who died in the postpartum (...) Intrauterine Tamponade With a Belfort-Dildy Balloon in the Treatment of Severe Immediate Postpartum Hemorrhage Intrauterine Tamponade With a Belfort-Dildy Balloon in the Treatment of Immediate Postpartum Hemorrhage - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100

2014 Clinical Trials

59. LNG-IUS at 2 Weeks Postpartum

of delivery No documented uterine rupture during delivery No active liver disease (resolved pre-eclampsia may enroll) No evidence of vaginal, cervical or uterine infection at time of LNG-IUS insertion No history of postpartum endometritis treated with antibiotics or a postpartum readmission for a dilation and curettage No pre-existing contraindication to a LNG-IUS as determined by the CDC's Medical Eligibility Criteria (MEC) category 3 or 4 Not currently incarcerated No known congenital or acquired (...) LNG-IUS at 2 Weeks Postpartum LNG-IUS at 2 Weeks Postpartum - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. LNG-IUS at 2 Weeks Postpartum (LNG-IUS) The safety and scientific validity of this study

2014 Clinical Trials

60. Does Preoperative Vaginal Preparation With Povidone-iodine Before Cesarean Delivery Reduce the Risk of Endometritis?

microorganisms as well as to remove certain species of bacteria. Condition or disease Intervention/treatment Phase Postpartum Endometritis Drug: povidone- iodine solution. Drug: placebo Phase 4 Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial) Actual Enrollment : 668 participants Allocation: Randomized Intervention Model: Parallel Assignment Masking: None (Open Label) Primary Purpose: Prevention Study Start Date : October 2010 Actual Primary Completion Date (...) Outcome Measures : rate of postpartum endometritis [ Time Frame: 6 weeks ] Endometritis was defined here as body temperature greater than 38.5C with concomitant foul-smelling discharge or abnormally tender uterus on bimanual examination Secondary Outcome Measures : morbidity [ Time Frame: two days ] Infectious morbidity was documented using established clinical criteria. Febrile morbidity was defined as a persistent fever of at least 38C for at least 24 hours after surgery and not associated

2011 Clinical Trials

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