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Postpartum Endometritis

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361. Evaluation of a Serology Diagnostic Kit for the Detection of Genital Mycoplasma in Pregnancy

are frequently found in the lower genital tract of sexually active men and women and are often considered as normal flora. However, Mycoplasma can spread and colonize the internal membranes and elicit an inflammatory response in the uterus initiating the cascade of events leading to precipitous delivery. It may also cause additional pregnancy complications such as chorioamnionitis, recurrent spontaneous abortions and postpartum endometritis. Traditional diagnostic methods, such as microbial culturing or PCR

2011 Clinical Trials

362. LCS12 vs. ENG Subdermal Implant (Nexplanon) Discontinuation Rate Study

not earlier than 6 weeks after delivery. If involution is substantially delayed, consider waiting until 12 weeks postpartum. Infected abortion or postpartum endometritis within 3 months prior to the Screening visit. Undiagnosed abnormal genital bleeding. Acute lower genital tract infection (until successfully treated) Acute or history of recurrent, pelvic inflammatory disease. Congenital or acquired uterine anomaly or any distortion of the uterine cavity (e.g. by fibroids) that, in the opinion (...) regular menstrual cycles (length of cycle 21 - 35 days). (Subject's history while not using hormonal contraceptives is sufficient, no washout period is required). Subject is willing and able to attend the scheduled study visits and to comply with the study procedures. Exclusion Criteria: Pregnancy or currently lactating Vaginal delivery, cesarean delivery or abortion within 6 weeks prior to Screening visit. Note: Postpartum LCS12 insertions should be postponed until uterus is fully involuted, however

2011 Clinical Trials

363. Elective caesarean section Full Text available with Trip Pro

distress, when there is no time to perform a regional anesthesia. Prevention of complications [ ] Postpartum infection is one of the main causes of maternal death and may account for 10% of maternal deaths globally. A caesarean section greatly increases the risk of infection and associated morbidity, estimated to be between 5 and 20 times as high, and routine use of antibiotic prophylaxis to prevent infections was found by a to substantially reduce the incidence of febrile morbidity. Infection can (...) occur in around 8% of women who have caesareans, largely , and wound infections. The use of preventative antibiotics in women undergoing caesarean section decreased wound infection, endometritis, and serious infectious complications by about 65%. Side effects and effect on the baby is unclear. Women who have caesareans can recognize the signs of fever that indicate the possibility of wound infection. Taking antibiotics before skin incision rather than after reduces the risk for the mother, without

2012 Wikipedia

364. Membrane Sweeping in Group B Streptococcus (GBS) Positive Patients

, reduce the frequency of pregnancy continuing beyond 41 or 42 weeks, and reduce the frequency of formal induction of labor. Thus, it is a safe and practical option for women who wish to avoid inductions of labor or postterm pregnancies. Group B streptococcus (GBS; streptococcus agalactiae) is a gram positive coccus that frequently colonizes the human genital tract. In pregnant women, GBS can cause urinary tract infections, chorioamnionitis, and postpartum endometritis. Newborn infants can also acquire

2010 Clinical Trials

365. Vaginal preparation with antiseptic solution before cesarean section for preventing postoperative infections. Full Text available with Trip Pro

Vaginal preparation with antiseptic solution before cesarean section for preventing postoperative infections. Cesarean delivery is one of the most common surgical procedures performed by obstetricians. Infectious morbidity after cesarean delivery can have a tremendous impact on the postpartum woman's return to normal function and her ability to care for her baby. Despite the widespread use of prophylactic antibiotics, postoperative infectious morbidity still complicates cesarean deliveries.To (...) determine if cleansing the vagina with an antiseptic solution before a cesarean delivery decreases the risk of maternal infectious morbidities, including endometritis and wound complications.We searched the Cochrane Pregnancy and Childbirth Group's Trials Register (December 2009).We included randomized trials assessing the impact of vaginal cleansing immediately before cesarean delivery with any type of antiseptic solution versus a placebo solution/standard of care on post-cesarean infectious

2010 Cochrane database of systematic reviews (Online)

366. Antibiotic prophylaxis versus no prophylaxis for preventing infection after cesarean section. Full Text available with Trip Pro

Antibiotic prophylaxis versus no prophylaxis for preventing infection after cesarean section. The single most important risk factor for postpartum maternal infection is cesarean section. Routine prophylaxis with antibiotics may reduce this risk and should be assessed in terms of benefits and harms.To assess the effects of prophylactic antibiotics compared with no prophylactic antibiotics on infectious complications in women undergoing cesarean section.We searched the Cochrane Pregnancy (...) ratio (RR) 0.45; 95% confidence interval (CI) 0.39 to 0.51, 50 studies, 8141 women), wound infection (average RR 0.39; 95% CI 0.32 to 0.48, 77 studies, 11,961 women), endometritis (RR 0.38; 95% CI 0.34 to 0.42, 79 studies, 12,142 women) and serious maternal infectious complications (RR 0.31; 95% CI 0.19 to 0.48, 31 studies, 5047 women). No conclusions can be made about other maternal adverse effects from these studies (RR 2.43; 95% CI 1.00 to 5.90, 13 studies, 2131 women). None of the 86 studies

2010 Cochrane database of systematic reviews (Online)

367. Study of Effectiveness and Safety of Azithromycin-based Extended-spectrum Prophylaxis to Prevent Post Cesarean Infection

-cesarean infection. Hypothesis: Compared to narrow-spectrum prophylaxis (i.e. cefazolin alone, or clindamycin if cephalosporin allergy) prior to surgical incision, the addition of extended-spectrum prophylaxis (azithromycin + cefazolin) reduces the incidence of post-cesarean infection. Condition or disease Intervention/treatment Phase Endometritis Wound Infection Abscess Surgical Site Infection Drug: Azithromycin and standard of care Drug: Placebo and standard of care Not Applicable Study Design Go (...) of care (cephazolin or clindamycin) Other Name: Zithromax Outcome Measures Go to Primary Outcome Measures : Participants With Endometritis and/or Wound Infection and/or Other Post-cesarean Infections (Occurring Within 6 Weeks of Delivery) [ Time Frame: Up to 6 weeks after delivery ] Endometritis was defined as the presence of at least two of the following signs with no other recognized cause: fever (temperature of at least 38°C [100.4°F]), abdominal pain, uterine tenderness, or purulent drainage from

2010 Clinical Trials

368. Postplacental Mirena IUD Insertion and Estimating Expulsion Rates.

standard for IUD insertion postpartum. Secondary outcomes will also be examined; endometritis, uterine perforation, continuation and pregnancy among others. Condition or disease Intervention/treatment Phase Estimating Rates of Expulsion Device: Levonorgestrel Intrauterine Device Phase 4 Detailed Description: The average expulsion rate for 6 week postpartum IUD insertion is approximately 10-12% with a range between 3-20% at 1 year. An acceptable expulsion rate for postplacental insertion (PPI) has (...) weeks postpartum ] Secondary Outcome Measures : breastfeeding [ Time Frame: 12 weeks ] request for IUD removal [ Time Frame: 12 weeks ] endometritis [ Time Frame: 12 weeks ] uterine perforation [ Time Frame: 12 weeks ] pregnancy [ Time Frame: 12 weeks ] Eligibility Criteria Go to Information from the National Library of Medicine Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about

2010 Clinical Trials

369. Antenatal Late Preterm Steroids (ALPS): A Randomized Placebo-Controlled Trial

., Endometritis: persistent postpartum temperature greater than 100.4 degrees F with uterine tenderness, cesarean delivery Hours From Randomization to Delivery [ Time Frame: Randomization through delivery ] Median interval of hours from randomization to delivery Median Length of Maternal Hospital Stay [ Time Frame: Delivery through hospital discharge ] Median length of maternal hospital stay in days Eligibility Criteria Go to Information from the National Library of Medicine Choosing to participate in a study

2010 Clinical Trials

370. Homeopathic Remedy for the Third Stage of Delivery

and Bellis perennis C30 Placebo Comparator: Placebo globules identical to true comparators Drug: Placebo globule identical to true homeopathy comparators Outcome Measures Go to Primary Outcome Measures : Hemoglobin levels at 2d postpartum [ Time Frame: 48h ] Secondary Outcome Measures : incidence of endometritis [ Time Frame: 7d ] time to extrusion of placenta following birth [ Time Frame: 24h ] duration of lochiae secretion [ Time Frame: 7days ] duration of third stage of labor [ Time Frame: 24h (...) ] assessment of quality-of-life parameters [ Time Frame: 7 days ] assess toxic effects of the homeopathic remedies [ Time Frame: 7 days ] serum cortisol levels [ Time Frame: within 12h postpartum ] state of perineum postpartum [ Time Frame: 48h ] Eligibility Criteria Go to Information from the National Library of Medicine Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study

2010 Clinical Trials

371. Does Vitamins C and E Supplementation of After Preterm Rupture of Membranes Prolong the Duration of Latency? A Prospective Randomized Controlled Study

delivery Secondary Outcome Measures : postpartum endometritis rate, early onset neonatal sepsis rate, [ Time Frame: days ] Other outcomes were the birth weight, mode of delivery, occurrence of clinical chorioamnionitis, postpartum endometritis, early onset neonatal sepsis, grade 3-4 intraventricular haemorrhage (IVH), stage 2-3 necrotizing enterocolitis (NEC), admission to intensive care unit (ICU), duration of stay in an intensive care unit and respiratory distress syndrome. Eligibility Criteria Go

2010 Clinical Trials

372. LCS12 vs Combined Oral Contraceptive (COC) User Satisfaction Study

should be postponed until the uterus is fully involuted, and not earlier than 6 weeks after delivery. If involution is substantially delayed, the investigator should consider waiting until 12 weeks postpartum. Infected abortion or postpartum endometritis within 3 months prior to the Screening Visit (Visit 1) Chronic, daily use of drugs that may increase serum potassium levels, such as nonsteroidal anti-inflammatory drugs (NSAIDs, eg. ibuprofen and naproxen), potassium-sparing diuretics (eg (...) that, according to the standards of the local laboratory, is negative for high-risk HPV. As determined by subject's history, subject has regular (ie, endogenous cyclicity without hormonal contraceptive use) menstrual cycles (length of cycle 21-35 days). Subject is willing and able to attend the scheduled study visits and to comply with the study procedures. Exclusion Criteria: Pregnancy or current lactation (less than 6 weeks since vaginal or Cesarean delivery or abortion). Note: Postpartum LCS12 insertions

2010 Clinical Trials

373. Fetal ST Segment and T Wave Analysis in Labor

through Delivery ] Chorioamnionitis Number of Participants Who Had a Postpartum Blood Transfusion [ Time Frame: Delivery through hospital discharge ] Blood transfusion from delivery and through hospital stay until discharge Number of Participants Experiencing Postpartum Endometritis [ Time Frame: Delivery through hospital discharge ] Postpartum endometritis Median Length of Hospital Stay [ Time Frame: From admission to labor and delivery through hospital discharge ] Days of stay in the hospital Number

2010 Clinical Trials

374. Antimicrobial prophylaxis for cesarean delivery before skin incision. Full Text available with Trip Pro

had lower rates of postpartum endometritis (2.2% compared with 3.9%) and wound infection (2.5% compared with 3.6%). After multivariable logistic regression, antimicrobial prophylaxis before skin incision remained associated with lower rates of endometritis (odds ratio [OR] 0.61, 95% confidence interval [CI] 0.47-0.79) and wound infection (OR 0.70, 95% CI 0.55-0.90). Antimicrobial prophylaxis before skin incision had no adverse effect on neonatal infection rates or on the evaluation

2009 Obstetrics and Gynecology

375. An unusual cause of delayed postpartum haemorrhage following caesarean section. (Abstract)

An unusual cause of delayed postpartum haemorrhage following caesarean section. Although less common in the UK, postpartum haemorrhage (PPH)--defined as blood loss of 500 ml or more within the first 24 h of delivery--remains a significant cause of maternal death worldwide. Haemorrhage between 24 h and 6 weeks post partum is termed "delayed PPH". Common causes include retention of gestational products or endometritis. Bleeding can be sudden and profound, resulting in rapid cardiovascular

2009 Emergency Medicine Journal

376. Efficacy of homeopathic remedies as prophylaxis of bovine endometritis. Full Text available with Trip Pro

Efficacy of homeopathic remedies as prophylaxis of bovine endometritis. The objective of this study was to evaluate the efficacy of 2 different homeopathic prophylactic strategies for the prevention of endometritis. The drugs used were Lachesis compositum (Lachesis), Carduus compositum (Carduus), and Traumeel LT (Traumeel). Each drug contained a mixed formula of homeopathic remedies. All 929 cows received the first treatment within 24 h postpartum. The second to fourth treatments were conducted (...) at 7 to 13, 14 to 20, and 21 to 27 d in milk, respectively. In the first group, the 4 treatments were Traumeel, Lachesis, Carduus, and Carduus, respectively (n = 206). In the second group, Lachesis was administered 3 times, followed by 1 treatment with Carduus (n = 198). The control group received 4 injections of saline (n = 189). In the fourth week after calving, the prevalence of clinical endometritis, uterine involution, and ovarian activity was monitored by rectal palpation

2009 Journal of dairy science Controlled trial quality: uncertain

377. Perioperative Antibiotic Prophylaxis for Nonlaboring Cesarean Delivery. Full Text available with Trip Pro

for reasons other than prophylaxis. The occurrence of postpartum endometritis, wound infection, and other, less common infection-related complications was compared between those who did and did not receive antibiotic prophylaxis. Results were adjusted for smoking, payer status, gestational age and body mass index at delivery, race, diabetes, antepartum infections, presence of anemia, operative time, type of cesarean delivery (primary or repeat), and center.Of the 9,432 women who met study criteria (...) , the 6,006 (64%) who received antibiotic prophylaxis were younger, heavier at delivery, and were more likely to be African American, receive public insurance, and have diabetes. Patients who received antibiotic prophylaxis were less likely to develop postpartum endometritis (121 [2.0%] compared with 88 [2.6%], adjusted odds ratio [OR] 0.40, 95% confidence interval [CI] 0.28-0.59) or wound infection (31 [0.52%] compared with 33 [0.96%], adjusted OR 0.49, 95% CI 0.28-0.86).Antibiotic prophylaxis

2009 Obstetrics and Gynecology

378. Effect of source of supplemental selenium on uterine health and embryo quality in high-producing dairy cows. (Abstract)

blastomeres, or proportions of grades 1 and 2, degenerated, and degenerated-unfertilized embryos/oocytes. Odds of subclinical endometritis on Day 30 postpartum more than doubled in cows with fever of unknown origin or acute puerperal metritis in the first 10 DIM. Fertilization rate tended to be reduced in cows with subclinical endometritis. In summary, replacing SS with an organic source of Se in diets not suboptimal in basal Se concentrations did not improve Se status, uterine health, fertilization (...) uterine horn was assessed at 30 DIM. The Ovsynch protocol was initiated at 42 DIM; ovarian responses to hormonal treatments were evaluated by ultrasonography. The uteri of cows were flushed 6d after timed AI for collection of embryos and oocytes. Plasma concentrations of Se and progesterone were measured throughout the postpartum period and during the reproductive protocol, respectively, and plasma glutathione peroxidase activity was determined 6d after AI. Concentrations of Se in pre- and postpartum

2009 Theriogenology Controlled trial quality: uncertain

379. A Pilot Study of Early Postpartum Intrauterine Contraception

A Pilot Study of Early Postpartum Intrauterine Contraception A Pilot Study of Early Postpartum Intrauterine Contraception - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. A Pilot Study of Early Postpartum (...) clinical trial to evaluate placement of the levonorgestrel-releasing intrauterine contraceptive 10 minutes - 48 hours postpartum. Condition or disease Intervention/treatment Phase Unplanned Pregnancy Drug: Levonorgestrel-Releasing Intrauterine Contraceptive System (LNG-IUS), 52 Mg, 5 Year Duration Phase 4 Detailed Description: This was a single arm cohort study of women who desired to receive a levonorgestrel releasing intrauterine system (LNG-IUS) within 48 hours of uncomplicated vaginal delivery

2009 Clinical Trials

380. Mirena in Idiopathic Menorrhagia

to international guidelines. These woman should also accept to be on contraception during the time period that they have Mirena in situ. Age limit 30-45 BMI= 18-34 Signed informed consent Exclusion Criteria: Medical conditions featured in the Mirena data sheet (See Appendix 1) that contraindicate its use, listed below: Known or suspected pregnancy; current or recurrent pelvic inflammatory disease; infection of the lower genital tract; postpartum endometritis; septic abortion during the past three months

2009 Clinical Trials

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