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Postinflammatory Hyperpigmentation

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81. Comparison of Q-switched Nd: YAG laser and fractional carbon dioxide laser for the treatment of solar lentigines in Asians. (Abstract)

Comparison of Q-switched Nd: YAG laser and fractional carbon dioxide laser for the treatment of solar lentigines in Asians. Solar lentigines are benign pigmented lesions that occur mostly on sun-exposed areas. Q-switched and ablative lasers are effective for removing these lesions but the high incidence of postinflammatory hyperpigmentation raises concern in darker skin types. The objective of this study is to compare the efficacy and degree of postinflammatory hyperpigmentation with the Q (...) effects were recorded.A total of 532 nm Q-switched Nd:YAG laser showed significant improvement of pigmentation over fractional CO2 laser at 6th and 12th week by both colorimeter assessment and physician grading scale (P < 0.05). No significant difference in postinflammatory hyperpigmentation from both lasers was observed. In terms of patient self-assessment, 80% of the patients treated with 532 nm Q-switched Nd:YAG laser had excellent results compared to 8% in fractional CO2 laser group. However

2017 Lasers in surgery and medicine Controlled trial quality: uncertain

82. Surgical Excision and Intralesional Steroid Injection for Prevention of Post Caesarean Keloid Recurrence

of participantsc with pruritis [ Time Frame: 6 months ] itching sensation at the site of wound Number of participants with residual postinflammatory hyperpigmentation -burning sensation -wound dehiscence [ Time Frame: 6 months ] redness or coloured pigmentation at wound site Number of participants with burning sensation [ Time Frame: 6 months ] feel burn at wound site Number of participants with wound dehiscence(complete) [ Time Frame: 6 months ] area of gaping of wound that requires secondary sutures Number

2017 Clinical Trials

83. Assessment of the Efficacy of Cryolipolysis on Saddlebags: A Prospective Study of 53 Patients. (Abstract)

decrease of 5.63 cm in thigh circumference; the mean decrease in fat layer thickness measured by ultrasound was 1.31 cm. The satisfaction questionnaire showed that 93.75 percent of patients were satisfied with the results. The mean visual analogue scale score was 1.66 of 10 after the session. Reversible skin changes such as postprocedure postinflammatory hyperpigmentation were observed in 8.33 percent of patients.Cryolipolysis is an effective technique for reducing saddlebag fat and is well tolerated (...) by patients. A substantial risk of skin lesions, including postinflammatory hyperpigmentation that resolved after a few months, was observed. Cryolipolysis is a good alternative to liposuction in women with moderate, well-localized saddlebags.Therapeutic, IV.

2017 Plastic and reconstructive surgery

84. The Clinical and Histological Effect of a Low-Fluence Q-Switched 1,064-nm Neodymium: Yttrium-Aluminum-Garnet Laser for the Treatment of Melasma and Solar Lentigo in Asians: Prospective, Randomized, and Split-Face Comparative Study. (Abstract)

. The increased EI, vascularity, and mast cell activity in patients with melasma and large-sized solar lentigo showed no improvement. The recurrence rates were 16.7% and 12.7% for melasma and solar lentigo, respectively. Postinflammatory hyperpigmentation developed in 1 patient, but no serious side effects were noted.Low-fluence QSNYL is effective in treating melasma and small type solar lentigo in Asians. The authors' study also demonstrated that lesion thickness, vascularity, and mast cell activity can

2017 Dermatologic Surgery Controlled trial quality: uncertain

85. What devices to use or not use in skin of color. (Abstract)

What devices to use or not use in skin of color. Lasers and light sources, as well as other energy devices, including radiofrequency, ultrasound, and cold-based therapies, can be used for treatment of aging, dyschromic, or texturally uneven skin. In patients with ethnic skin (ie, skin of color), energy devices are used more cautiously to avoid adverse events. The most common and concerning adverse event is postinflammatory hyperpigmentation. Lower fluence, longer pulse durations, and careful

2016 Seminars in Cutaneous Medicine and Surgery

86. A review of melasma treatment focusing on laser and light devices. (Abstract)

A review of melasma treatment focusing on laser and light devices. Melasma is a pigmentary disorder of unclear etiology with numerous treatment options and high recurrence rates. Laser and light therapies may be utilized cautiously as second- or third-line options for recalcitrant melasma, but low-energy settings are preferred due to the risk of postinflammatory hyperpigmentation and melasma stimulation. Commonly used lasers include the low-fluence 1064-nm Q-switched neodymium-doped yttrium

2016 Seminars in Cutaneous Medicine and Surgery

87. Microneedling: A Comprehensive Review. (Abstract)

and for facilitation of transdermal drug delivery. While permanent adverse events are uncommon, transient erythema and postinflammatory hyperpigmentation are more commonly reported.Microneedling appears to be an overall effective and safe therapeutic option for numerous dermatologic conditions. Larger and more randomized controlled trials are needed to provide greater data on the use of microneedling for different dermatologic conditions in different skin types.

2016 Dermatologic Surgery

88. Nonablative Fractional Laser Resurfacing for Acne Scarring in Patients With Fitzpatrick Skin Phototypes IV-VI. (Abstract)

compared with baseline (p < .001) for both treatment densities. Five of 7 and 3 of 7 patients in the higher and lower density group, respectively, experienced mild or moderate hyperpigmentation as an investigator observed site reaction.The nonablative 1550-nm fractional laser is safe and efficacious in treating acne scaring in Fitzpatrick skin types IV to VI. Self-limited postinflammatory hyperpigmentation was a common occurrence, especially with higher treatment densities.

2016 Dermatologic Surgery Controlled trial quality: uncertain

89. The Clinical Effectiveness of Intralesional Injection of 2% Zinc Sulfate Solution in the Treatment of Common Warts. Full Text available with Trip Pro

postinflammatory hyperpigmentation in 90 patients (75%), scaring in 9 patients (7.5%), and ulceration in 3 patients (2.5%). Recurrence occurred in 3 lesions (1.33%). Conclusion. The clinical data indicate that intralesional injection of 2% zinc sulfate is an effective maneuver in the treatment of common warts; however, its associated complications limit its use.

2016 Scientifica Controlled trial quality: uncertain

90. Comparison of Nonablative Fractional Erbium Laser 1,340 nm and Microneedling for the Treatment of Atrophic Acne Scars: A Randomized Clinical Trial. Full Text available with Trip Pro

Comparison of Nonablative Fractional Erbium Laser 1,340 nm and Microneedling for the Treatment of Atrophic Acne Scars: A Randomized Clinical Trial. The efficacy and safety of nonablative fractional laser for acne scars treatment has been described in several studies. Recently, microneedling treatment has been showing promising results with lower costs, quick healing time, and low risk of postinflammatory hyperpigmentation (PIH).To compare the effectiveness and safety of nonablative fractional

2016 Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] Controlled trial quality: uncertain

91. Development of Photoonycholysis with Vandetanib Therapy Full Text available with Trip Pro

therapies. In addition, histopathologic findings and reflectance confocal microscopy imaging performed in one patient suffering from photodistributed skin hyperpigmentation both strengthen the likelihood of a postinflammatory mechanism. Clinicians should be aware of these underestimated but very characteristic photoinduced adverse events, which can lead to treatment interruption and require very strict photoprotective measures in treated patients. (...) 2 patients developing photosensitivity reactions with vandetanib therapy, including photoonycholysis. Our patients presented a wide range of phototoxic reactions with exaggerated sunburn reactions solely located to photoexposed areas or hyperpigmentation with visible blue dots. More importantly, both patients concomitantly developed nail changes consistent with type 1 photoonycholysis, which had never been reported so far neither with vandetanib therapy nor with other anticancer-targeted

2016 Skin appendage disorders

92. Increased Activity and Number of Epidermal Melanocytes in Lesional Psoriatic Skin. Full Text available with Trip Pro

melanocyte activity and numbers are increased in the epidermal compartment of psoriatic lesions providing an explanation for postinflammatory hyperpigmentation.© 2016 S. Karger AG, Basel. (...) Increased Activity and Number of Epidermal Melanocytes in Lesional Psoriatic Skin. Psoriatic lesions may resolve with hypo- or hyperpigmentation. The involvement of melanocytes in this dichotomous clinical outcome is not fully investigated.Qualitative and quantitative assessment of melanocytes in untreated lesional and non-lesional psoriatic skin (n = 15) and healthy controls (n = 10).Skin biopsies were labelled immunohistochemically (APAAP technique) with the antimelanocyte monoclonal

2016 Dermatology

93. High versus moderate energy use of bipolar fractional radiofrequency in the treatment of acne scars: a split-face double-blinded randomized control trial pilot study. (Abstract)

follow-visit, high energy side demonstrated significant improvement compared with moderate energy side (p = 0.03). Postinflammatory hyperpigmentation (PIH) developed in 21/120 sessions in high energy side (17.5 %) and 16/120 sessions in moderate energy side (13.3 %). Pain score and the duration of erythema after treatments were significant higher on the side that was treated with high energy. Bipolar FRF device was safe and effective in the treatment of atrophic acne scars in Asians. High energy

2015 Lasers in medical science Controlled trial quality: uncertain

94. Treatment of Acquired and Small Congenital Melanocytic Nevi With Combined Er: YAG Laser and Long-Pulsed Alexandrite Laser in Asian Skin. Full Text available with Trip Pro

in 24 Korean patients were treated with Er:YAG laser followed by long-pulsed alexandrite laser at 1-month intervals.At 8 weeks after the final treatment, all treated nevi showed complete removal of pigmentation, and the mean overall improvement score assessed by physicians, with a quartile grading scale, was 3.6 ± 0.7. The mean number of treatment sessions required to treat CMN (1.5 ± 0.3) was significantly greater than that for junctional (1.1 ± 0.2) or compound (1.2 ± 0.5) AMN. Postinflammatory (...) hyperpigmentation (4.6%), erythema (9.2%), hypertrophic scars (1.5%), and mild atrophic scars (10.8%) were observed, but all resolved within 6 months, except for hypertrophic scars and 1 atrophic scar. Recurrence of pigmentation was observed in 1 CMN (1.5%) during 6 months of follow-up.Combined treatment with Er:YAG laser and long-pulsed alexandrite laser is effective for the removal of small benign melanocytic nevi with minimal adverse effects and low recurrence rates.

2015 Dermatologic Surgery

95. Multidisciplinary Quality Improvement Guidelines for the Treatment of Lower Extremity Superficial Venous Insufficiency with Ambulatory Phlebectomy From the Society of Interventional Radiology, Cardiovascular Interventional Radiological Society of Europe,

- mentationmayresultfromhemosiderin Kundu et al  9 Volume 21 Number 1staining (after hematoma resorption) and postinflammatory melanocytic hy- peractivity. Hyperpigmentation most commonly fades in weeks to months without treatment. However, sun pro- tection(ie,sunblockandskincoverings) and UV avoidance are critical to avoid melanogenesis in treatment areas. Con- tact dermatitis is very rare because of the new generation of hypoallergenic topical medications and dressings. Visi- ble scarring after AP is rare and can (...) ). Cutaneous Complications A number of different types of skin lesionsmayoccurafterAP.Mostcanbe prevented by proper application of postoperative dressings. Blisters occur secondary to skin shearing (eg, with Steri-Strips or adhesive bandages) and mayleadtopostbulloushypopigmenta- tion (transient or permanent) or tran- sient hyperpigmentation. Blister forma- tion may be prevented by avoiding the use of adhesive dressings and using gauze dressings with a short- or long- stretch bandage. Transient hyperpig

2010 Society of Interventional Radiology

96. Q-switched Nd: YAG laser versus trichloroacetic acid peeling in the treatment of melasma among Egyptian patients. (Abstract)

was significantly higher among patients treated with TCA 25% (p < .001). Epidermal type of melasma was significantly improved compared with the dermal type (p = .0029). Q-switched neodymium-doped:yttrium aluminum garnet laser showed the highest incidence of postinflammatory hyperpigmentation (53.3%).Trichloroacetic acid peeling is effective in the treatment of melasma, TCA 25% was the most effective concentration. Q-switched neodymium-doped:yttrium aluminum garnet laser is not recommended in the treatment (...) Q-switched Nd: YAG laser versus trichloroacetic acid peeling in the treatment of melasma among Egyptian patients. Melasma is a common disorder of facial hyperpigmentation that is often resistant to treatment.To evaluate the efficacy of trichloroacetic acid (TCA) peeling in comparison with double frequency Q-switched neodymium-doped:yttrium aluminum garnet (QS-Nd:YAG) laser in the treatment of melasma.Sixty-five adult Egyptian female patients with melasma were enrolled in this study. Wood light

2014 Dermatologic Surgery Controlled trial quality: uncertain

97. Objective Evaluation of the Clinical Efficacy of Fractional Radiofrequency Treatment for Acne Scars and Enlarged Pores in Asian Skin. (Abstract)

Objective Evaluation of the Clinical Efficacy of Fractional Radiofrequency Treatment for Acne Scars and Enlarged Pores in Asian Skin. Ablative fractional lasers can effectively treat acne scars and enlarged pores, but cause considerable pain and downtime for patients, as well as potentially causing postinflammatory hyperpigmentation (PIH), especially in Asian skin.To evaluate the efficacy of a novel bipolar radiofrequency (RF)-based fractional device to treat acne scars and enlarged pores

2014 Dermatologic Surgery

98. Polypodium leucotomos as an Adjunct Treatment of Pigmentary Disorders. Full Text available with Trip Pro

improved the severity of melasma in women after 12 weeks. Three randomized, double-blind, placebo-controlled studies have demonstrated significant improvements in vitiligo when oral Polypodium leucotomos therapy was combined with psoralens plus ultraviolet A and narrowband ultraviolet B. No controlled studies have assessed the efficacy of Polypodium leucotomos for the treatment of postinflammatory hyperpigmentation; however, its known antioxidant and anti-inflammatory properties and demonstrated (...) effectiveness for melasma support its use for treating this condition. No adverse events have been associated with the use of Polypodium leucotomos.In addition to preventing many harmful effects associated with sunlight exposure, orally administered Polypodium leucotomos also appears to provide adjunctive benefits in treating vitiligo, melasma, and may have the potential to help with postinflammatory hyperpigmentation.

2014 The Journal of clinical and aesthetic dermatology Controlled trial quality: uncertain

99. A split-face, evaluator-blind randomized study on the early effects of Q-switched Nd:YAG laser plus Er:YAG micropeel (combined therapy) versus Q-switched Nd:YAG alone in light solar lentigines in Asians. (Abstract)

of postinflammatory hyperpigmentation (PIH) with combined therapy (73.3 vs 40%), the degree of pigment reduction in the combined side of the face was found significantly lower than that of the QSNY-alone side at 1-month follow-up (P = 0.014). Although our study results show that both combined therapy and QSNY alone are capable of reducing pigmentation, QSNY alone is considered to have more favorable qualities than combined treatment for light solar lentigines in Asians.

2014 Lasers in medical science Controlled trial quality: uncertain

100. Melasma treatment using an erbium:YAG laser: a clinical, immunohistochemical, and ultrastructural study. (Abstract)

area and severity index score decreased dramatically.Erbium:YAG laser resurfacing effectively improves melasma; however, the almost universal appearance of transient postinflammatory hyperpigmentation necessitates prompt and persistent intervention.© 2014 The International Society of Dermatology.

2014 International Journal of Dermatology

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