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121. Balneological outpatient treatment for patients with knee osteoarthritis; an effective non-drug therapy option in daily routine? (Abstract)

Balneological outpatient treatment for patients with knee osteoarthritis; an effective non-drug therapy option in daily routine? This study aims to compare the effects of balneological treatments applied at consecutive and intermittent sessions without interfering with their daily routine in patients with knee osteoarthritis. This is a randomized, controlled, single-blind clinical trial. Fifty patients diagnosed with knee osteoarthritis were included. The patients were divided into two groups (...) to be maintained in terms of role-physical (SF-36) parameter, while the well-being of group 1 was unable to be maintained in terms of pain, WOMAC (pain, physical functions, total), and SF-36 (physical functioning, role-physical, pain, role-emotional, and mental health) variables, compared to data obtained immediately after treatment. Our study suggests that traditional and intermittent balneological therapies have similar efficacy in patients with knee osteoarthritis.

2016 International journal of biometeorology Controlled trial quality: uncertain

122. Drug therapy during pregnancy: implications for dental practice. (Abstract)

Drug therapy during pregnancy: implications for dental practice. Pregnancy is accompanied by various physiological and physical changes, including those found in the cardiovascular, respiratory, gastrointestinal, renal and haematological systems. These alterations in the pregnant patient may potentially affect drug pharmacokinetics. Also, pharmacotherapy presents a unique matter due to the potential teratogenic effects of certain drugs. Although medications prescribed by dentists are generally (...) safe during pregnancy, some modifications may be needed. In this article we will discuss the changes in the physiology during pregnancy and its impact on drug therapy. Specific emphasis will be given to the drugs commonly given by dentists, namely, local anaesthetics, analgesics, antibiotics and sedatives.

2016 British Dental Journal

123. Incidence of Malignancies in a Cohort of Psoriatic Arthritis Patients Taking Traditional Disease Modifying Antirheumatic Drug and Tumor Necrosis Factor Inhibitor Therapy: An Observational Study. (Abstract)

Incidence of Malignancies in a Cohort of Psoriatic Arthritis Patients Taking Traditional Disease Modifying Antirheumatic Drug and Tumor Necrosis Factor Inhibitor Therapy: An Observational Study. Psoriatic arthritis (PsA) is an inflammatory arthropathy, associated with skin and/or nail psoriasis. As suggested in 2012 by the Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA), studies devoted to assess cancer in the PsA population are still limited and need (...) to be increased. Therefore, the aim of this study was to determine the incidence of malignancies in patients with PsA who are taking conventional and biologic therapies.A cohort of patients with PsA was followed prospectively. At first visit, as well as at each 3-4 month followup visit, according to standardized clinical practice, medical history, and physical and laboratory findings were recorded. Information on the presence of comorbidities, as well as malignancies, was collected. At each visit, data were

2016 Journal of Rheumatology

124. Systematic Approaches to Rehabilitative Medical Treatment of Patients: A Review of Clinical Effectiveness and Guidelines

with standard exercises and (ii) undiagnosed patients in a waitlist condition.8 No evidence-based guidelines were identified regarding systematic approaches to physical rehabilitation treatment. Files Rapid Response Summary with Critical Appraisal Published : November 9, 2018 Follow us: © 2019 Canadian Agency for Drugs and Technologies in Health Get our newsletter: (...) Systematic Approaches to Rehabilitative Medical Treatment of Patients: A Review of Clinical Effectiveness and Guidelines Systematic Approaches to Rehabilitative Medical Treatment of Patients: A Review of Clinical Effectiveness and Guidelines | CADTH.ca Find the information you need Systematic Approaches to Rehabilitative Medical Treatment of Patients: A Review of Clinical Effectiveness and Guidelines Systematic Approaches to Rehabilitative Medical Treatment of Patients: A Review of Clinical

2018 Canadian Agency for Drugs and Technologies in Health - Rapid Review

125. Policy on Medically-Necessary Care

and pro-vision of individual and community-based health care programs to achieve comprehensive health care. 2. Establishment of a dental home for all children by 12 months of age in order to institute an individualized preventive oral health program based upon each patient’s unique caries risk assessment. 3. Healthcare providers who diagnose oral disease to either provide therapy or refer the patient to a primary care dentist or dental/medical specialist as dictated by the nature and complexity (...) 2000;22(1):27-32. 67. Prabhu NT, Nunn JH, Evans DJ. A comparison of costs in providing dental care for special needs patients under sedation or general anesthesia in the North East of England. Prim Dent Care 2006;13(4):125-8. 68. Institute of Medicine Committee on Medicare Coverage Extensions. Medically necessary dental services. In; Field MJ, Lawrence RL, Zwanziger L, eds. Extending Medicare Coverage for Preventive and Other Services. Washington (DC): National Academies Press (US); 2000. Available

2019 American Academy of Pediatric Dentistry

126. Medical decision-making in paediatrics: Infancy to adolescence

Medical decision-making in paediatrics: Infancy to adolescence Medical decision-making in the paediatric population is complicated by the wide variation in physical and psychological development that occurs as children progress from infancy to adolescence. Parents and legal guardians are the de facto decision-makers in early infancy, but thereafter, the roles of parents/legal guardians and paediatric patients become ever more complex. Health care providers (HCPs), while not decision-makers per (...) se, have a significant role in medical decision-making throughout childhood. This statement outlines the ethical principles of medical decision-making for HCPs involved in caring for paediatric patients. This revision focuses on individual decision-making in the context of the patient–provider relationship and provides increased guidance for dealing with disagreements. Keywords: Advanced directives; Best Interests; Emancipated minors; End-of-life; Informed consent; Mature minors; SDM

2018 Canadian Paediatric Society

127. The Patient Centred Medical Home: barriers and enablers to implementation

The Patient Centred Medical Home: barriers and enablers to implementation The Patient Centred Medical Home: barriers and enablers to implementation An Evidence Check rapid review brokered by the Sax Institute for COORDINARE. January 2018 An Evidence Check rapid review brokered by the Sax Institute for COORDINARE. January 2018. This report was prepared by: Jim Pearse and Deniza Mazevska – Health Policy Analysis Pty Ltd. January 2018 © Sax Institute 2018 This work is copyright. It may (...) : Pearse J, Mazevska D. The Patient Centered Medical Home: barriers and enablers: an Evidence Check rapid review brokered by the Sax Institute (www.saxinstitute.org.au) for COORDINARE, 2018. Disclaimer: This Evidence Check Review was produced using the Evidence Check methodology in response to specific questions from the commissioning agency. It is not necessarily a comprehensive review of all literature relating to the topic area. It was current at the time of production (but not necessarily

2018 Sax Institute Evidence Check

128. Pregnant women and poor sleep: medication is rarely the right solution

women and poor sleep: medication is rarely the right solution In the case of poor sleep during pregnancy, sedatives are rarely the right solution. Non-drug measures are preferable. When a pregnant woman is troubled by poor sleep, preference should be given to non-drug measures: avoid consumption of stimulants and heavy meals and follow the usual advice such as physical activity in the run-up to bedtime, going to bed only when sleepy, getting up at the same time every day. At present, given what (...) and third trimesters, provided that it is in the form of low-concentration aqueous or hydroalcoholic extract. In general, it is preferable to avoid taking concentrated plant extracts repeatedly for medicinal purposes during pregnancy, due to uncertainties about their effects. Some drugs with an adverse harm-benefit balance for pregnant women or the unborn child should be ruled out. These include alimemazine and promethazine; fast-acting benzodiazepines such as flunitrazepam and triazolam; melatonin

2018 Prescrire

129. Open letter from academics, practitioners, students and members of the public to the British Medical Association, the British Medical Journal publishing group, and the British Association of Sports and Exercise Medicine regarding editorial governance of t

-media portal that provides original research, reviews and debate relating to clinically-relevant aspects of sport and exercise medicine, including physiotherapy, physical therapy and rehabilitation. We contribute to innovation (research), education (teaching and learning) and knowledge translation (implementing research into practice and policy). Our web, print, video and audio material, combined with active social media, serves the international community of clinicians who treat active people (...) Open letter from academics, practitioners, students and members of the public to the British Medical Association, the British Medical Journal publishing group, and the British Association of Sports and Exercise Medicine regarding editorial governance of t Open letter from academics, practitioners, students and members of the public to the British Medical Association, the British Medical Journal publishing group, and the British Association of Sports and Exercise Medicine regarding editorial

2018 British Journal of Sports Medicine Blog

130. Integration of Dermatology-Focused Physical Diagnosis Rounds and Case-Based Learning within the Internal Medicine Medical Student Clerkship Full Text available with Trip Pro

Integration of Dermatology-Focused Physical Diagnosis Rounds and Case-Based Learning within the Internal Medicine Medical Student Clerkship Over half of dermatologic conditions are seen by nondermatologists, yet medical students receive little dermatology education. Medical students in the clinical years of training at our institution felt insecure in their physical diagnosis skills for dermatologic conditions.The objective of this study was to implement dermatology-focused curricula within (...) the Internal Medicine (IM) Core Clerkship to increase student confidence in diagnosing skin diseases.Two dermatology-focused sessions were integrated into the IM Clerkship. A faculty dermatologist leads students on a dermatology-focused physical diagnosis "Skin Rounds", where patients are seen at the bedside and students practice describing skin lesions and forming a differential diagnosis. Students also participate in a case-based active learning session. A dermatologist selects images of common skin

2016 Journal of medical education and curricular development

131. Nootropic efficacy of Satvavajaya Chikitsa and Ayurvedic drug therapy: A comparative clinical exposition. Full Text available with Trip Pro

Nootropic efficacy of Satvavajaya Chikitsa and Ayurvedic drug therapy: A comparative clinical exposition. Ayurveda is known for philosophical basis, and its approach to psychological ailments is quite different from conventional system of management. Satvavajaya Chikitsa (Ayurvedic psychotherapy) is a nonpharmacological approach aimed at control of mind and restraining it from unwholesome Artha (objects) or stressors. Withdrawal of the mind from unwholesome objects is known as Sattvavajaya (...) Chikitsa or it is a treatment by Self Control. Charaka defines it as a mind controlling therapy in which a stress has been laid on restraining of mind from unwholesome objects. Thus, it includes all the methods of Manonigraha and Astanga Yoga (Yogic techniques) too. Indian philosophy portrays Astanga Yoga as a primary tool to control mind; hence it can be used as Satvavajaya Chikitsa.To evaluate efficacy of Satvavajaya Chikitsa and Aushadhiya Medhya Chikitsa for improving Smriti in young healthy

2015 International journal of yoga Controlled trial quality: uncertain

132. Biomarkers for Therapy Response in Drug-resistant Tuberculosis

Perspective: Prospective Official Title: Biomarkers for Therapy Response in Drug-resistant Tuberculosis Study Start Date : March 2013 Estimated Primary Completion Date : December 2018 Estimated Study Completion Date : December 2020 Resource links provided by the National Library of Medicine related topics: resources: Groups and Cohorts Go to Group/Cohort Intervention/treatment M/XDR The M/XDR-cohort will consist of patients with a suspected infection with an M/XDR-TB strain.The suspicion will be held (...) Biomarkers for Therapy Response in Drug-resistant Tuberculosis Biomarkers for Therapy Response in Drug-resistant Tuberculosis - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Biomarkers for Therapy Response

2015 Clinical Trials

133. HIV Drug Switch Followed by HCV Therapy in HIV-HCV Co-Infection

HIV Drug Switch Followed by HCV Therapy in HIV-HCV Co-Infection HIV Drug Switch Followed by HCV Therapy in HIV-HCV Co-Infection - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. HIV Drug Switch Followed (...) , during and after HCV antiviral therapy. Drug-drug interactions (DDI) DDI between E/C/F/TAF and LPV-SOF have been well evaluated and no clinically significant interactions have been identified. A switch to E/C/F/TAF in the context of LPV-SOF HCV antiviral treatment preparation may be particularly beneficial because of its: favorable side effect profile once daily STR formulation known DDI profile with LPV-SOF neutral effect on liver fibrosis improved kidney and bone safety profile with the use of TAF

2015 Clinical Trials

134. Short-Term Dual Antiplatelet and Maintenance CloPidogrel Therapy After Drug-Eluting Stent Implantation

Update Posted : February 23, 2017 Sponsor: CHEOL WHAN LEE, M.D., Ph.D Collaborators: CardioVascular Research Foundation, Korea Medtronic Chong Kun Dang Pharmaceutical Corp. Information provided by (Responsible Party): CHEOL WHAN LEE, M.D., Ph.D, Asan Medical Center Study Details Study Description Go to Brief Summary: The purpose of this study is to compare short-term (6-month Dual Anti Platelet Therapy(DAPT) followed by clopidogrel monotherapy) vs. standard long-term dual antiplatelet strategies (24 (...) Intervention Model: Parallel Assignment Masking: None (Open Label) Primary Purpose: Treatment Official Title: Short-Term Dual Antiplatelet and Maintenance CloPidogrel Therapy After Drug-Eluting Stent Implantation : STAMP-DES Trial Actual Study Start Date : December 22, 2015 Actual Primary Completion Date : February 13, 2017 Actual Study Completion Date : February 13, 2017 Resource links provided by the National Library of Medicine available for: Arms and Interventions Go to Arm Intervention/treatment

2015 Clinical Trials

135. Study of Intraparenchymal Therapy With Irinotecan Drug Eluting Beads as Adjunct to Recurrent Surgically Resectable High Grade Glioma

) as a Adjunct Therapy to Best Standard of Care in Patients With Recurrent, Surgically Resectable High Grade Glioma Study Start Date : July 2011 Estimated Primary Completion Date : August 2016 Estimated Study Completion Date : June 2017 Resource links provided by the National Library of Medicine available for: resources: Arms and Interventions Go to Arm Intervention/treatment Experimental: Treatment arm Intraparenchymal administration of CM-BC2 irinotecan drug-eluting bead in recurrent high grade glioma (...) Study of Intraparenchymal Therapy With Irinotecan Drug Eluting Beads as Adjunct to Recurrent Surgically Resectable High Grade Glioma Study of Intraparenchymal Therapy With Irinotecan Drug Eluting Beads as Adjunct to Recurrent Surgically Resectable High Grade Glioma - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You

2015 Clinical Trials

136. Appropriate prescribing of psychotropic medication for non-cognitive symptoms in people with dementia

Grading of Recommendations Assessment, Development and Evaluation GDG Guideline Development Group GDP Global Domestic Product MCI Mild Cognitive Impairment MHBC Ministry of Health British Columbia MHRA Medicines and Healthcare products Regulatory Agency NCEC National Clinical Effectiveness Committee NHMRC National Health and Medical Research Council NHS National Health Service NICE National Institute for Health and Care Excellence NPI Neuropsychiatric Inventory PBS Pharmaceutical Benefit Scheme PDD (...) . However, most evidence is based on common dementia types, particularly Alzheimer’s dementia; this needs to be borne in mind by the user when applying the evidence to other dementia types. Clinicians’ attention is also drawn to the fact that many psychotropic medications are used “off label” for people with dementia, particularly antipsychotic medication. While this is not prohibited by medicine regulations, it does require particular caution by the prescriber. This National Clinical Guideline

2019 National Clinical Guidelines (Ireland)

137. Principles of Pediatric Patient Safety: Reducing Harm Due to Medical Care

the standardization of concentrations in compounded medications; developing, spreading, and advocating for pediatric-specific health care information technology for drug delivery; educating providers on methods to reduce medication errors, including medication reconciliation; ensuring that providers maintain access to and proficiency in the use of a comprehensive and current pharmaceutical knowledge base; and creating policies that advocate for safe medication delivery to children in all health care settings (...) . Principles of Pediatric Patient Safety: Reducing Harm Due to Medical Care Brigitta U. Mueller , Daniel Robert Neuspiel , Erin R. Stucky Fisher , COUNCIL ON QUALITY IMPROVEMENT AND PATIENT SAFETY, COMMITTEE ON HOSPITAL CARE Abstract Pediatricians render care in an increasingly complex environment, which results in multiple opportunities to cause unintended harm. National awareness of patient safety risks has grown since the National Academy of Medicine (formerly the Institute of Medicine) published its

2019 American Academy of Pediatrics

138. American Gastroenterological Association Institute Guideline on the Medical Management of Opioid-Induced Constipation Full Text available with Trip Pro

., Dorn, S.D. et al. American Gastroenterological Association medical position statement on constipation. Gastroenterology . 2013 ; 144 : 211–217 | | | | | Once a diagnosis of OIC has been confirmed and other potential causes of constipation are excluded, the recommendations here can help guide appropriate evidence-based management. This guideline focuses on the medical management of OIC. Therefore, it does not address the role of psychological therapy, alternative medicine approaches, surgery (...) control, the AGA recommends escalation of therapy to PAMORA drugs with high- or moderate-quality evidence of efficacy, namely naldemedine and naloxegol. The AGA also conditionally recommends use of methylnatrexone. Due to insufficient evidence, the AGA did not issue a recommendation regarding use of either lubiprostone or prucalopride in OIC. The recommendations are similar to those proposed by recent clinical guidelines related to OIC published by the American Academy of Pain Medicine x 25 Muller

2019 American Gastroenterological Association Institute

139. Medical management of abortion

of abortion (medical abortion): Use of pharmacological drugs to terminate pregnancy. Sometimes the terms “non-surgical abortion” or “medication abortion” are also used. Routes of misoprostol administration: oral pills are swallowed; buccal pills are placed between the cheek and gums and swallowed after 30 minutes; sublingual pills are placed under the tongue and swallowed after 30 minutes; vaginal pills are placed in the vaginal fornices (deepest portions of the vagina) and the individual is instructed (...) , auxiliary nurse midwives, nurses, midwives, associate/advanced associate clinicians, and non-specialist and specialist doctors. Doctors of complementary systems of medicine can be providers of this service in health system contexts with an established mechanism for the participation of such doctors in other tasks related to maternal and reproductive health (10). Alongside non-specialist and specialist doctors, the following cadres can provide medical abortion for pregnancies = 12 weeks in contexts where

2019 World Health Organisation Guidelines

140. Breast Cancer: Medication Use to Reduce Risk

-sensitive epithelial cells where breast cancer can develop. These medications have been approved by the US Food and Drug Administration for risk reduction of breast cancer. Aromatase inhibitors inhibit conversion of androgen to estrogen and can reduce risk of ER-positive breast cancer by decreasing the amount of estrogen available to bind to estrogen-sensitive epithelial cells. Aromatase inhibitors have been evaluated for risk reduction of breast cancer in clinical trials, although they are primarily (...) used for treatment rather than risk reduction of primary cancer. Aromatase inhibitors are not currently approved by the US Food and Drug Administration for risk reduction of primary breast cancer. This recommendations is consistent with the 2013 USPSTF recommendation. As before, the USPSTF recommends offering risk-reducing medications to women at increased risk for breast cancer and at low risk for adverse medication effects (B recommendation) and recommends against routine use of risk-reducing

2019 U.S. Preventive Services Task Force

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