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101. Association between migration and physical activity among medical students from a university located in Lima, Peru. Full Text available with Trip Pro

Association between migration and physical activity among medical students from a university located in Lima, Peru. To evaluate the association between migration and physical activity among medical students from a university located in Lima, Peru.A cross-sectional study was conducted among second-year medical students from a Peruvian university. Data on moderate- to vigorous-intensity physical activity (MVPA) and migration features were obtained through a self-report questionnaire. To assess (...) , adjusted analysis showed that the frequency of performing MVPA for ≤30 minutes/week was greater among those who migrated less than five years ago (PR: 1.43; 95% CI: 1.05-1.93) and among those who migrated to continue their studies (PR: 1.44; 95% CI: 1.06-1.94), compared to non-migrants.In our population, being a migrant was not associated with physical activity. However, low physical activity was more prevalent among recent migrants and among those who had migrated to study, compared to non-migrants.

2019 PLoS ONE

102. Impact of Chronic Medical Condition Development on Longitudinal Physical Function from Mid- to Early Late-Life: The Study of Women's Health Across the Nation. (Abstract)

Impact of Chronic Medical Condition Development on Longitudinal Physical Function from Mid- to Early Late-Life: The Study of Women's Health Across the Nation. Chronic medical conditions (CMCs) often emerge and accumulate during the transition from mid- to late-life, and the resulting multimorbidity can greatly impact physical function. We assessed the association of CMC presence and incidence on trajectories of physical function from mid- to early late-life in the Study of Women's Health Across (...) the Nation.Physical function was assessed at eight clinic visits (average 14 years follow-up) using the physical function subscale of the Short Form-36. CMCs included osteoarthritis, diabetes, stroke, hypertension, heart disease, cancer, osteoporosis, and depressive symptomatology, and were considered cumulatively. Repeated-measures Poisson models estimated longitudinal change (expressed as percent difference) in physical function by chronic CMCs. Change-points assessed physical function change coincident

2020 Biological Sciences and Medical Sciences

103. Mind and body exercises (MBE), prescribed antidepressant medication, physical exercise and depressive symptoms - a longitudinal study. (Abstract)

Mind and body exercises (MBE), prescribed antidepressant medication, physical exercise and depressive symptoms - a longitudinal study. Earlier studies show that participation in mind and body exercises (MBE) is cross-sectionally associated with high levels of depressive symptoms and antidepressants. This study investigates the longitudinal interrelationship between depressive symptoms, MBE and antidepressants.3269 men and 4318 women aged 24-74 years participated in the Swedish Longitudinal (...) Occupational Survey of Health (SLOSH). Measures of MBE practice and depressive symptoms were drawn from the SLOSH questionnaire, data on prescription drugs were obtained from the Swedish Prescribed Drug Register. Structural Equation Modeling (SEM) was used to analyze temporal relationships.Both MBE practice and antidepressants in 2012 was associated with higher levels of depressive symptoms two years later. Depressive symptoms in turn were associated with higher levels of later MBE practice

2020 Journal of Affective Disorders

104. Antihypertensive medications and physical function in older persons. (Abstract)

Antihypertensive medications and physical function in older persons. To further inform benefits and risks of medications on physical function in aging populations, we have evaluated the associations of antihypertensive (antiHTN) class and number used with skeletal muscle function, mobility, sedentary time, and symptoms in older persons.Using baseline data from the Lifestyle Interventions and Independence in Elder (LIFE) study (N = 1567, mean age 78.9 years) and multivariable models, we (...) evaluated cross-sectional associations of antiHTN class and number used with physical measures and symptom questionnaires. AntiHTN class included diuretics, angiotensin converting enzyme inhibitors (ACEi), angiotensin receptor blockers (ARB), calcium channel blockers (CCB), and beta blockers (BB). Physical measures included respiratory muscle weakness (maximal inspiratory pressure), grip weakness (dynamometer), impaired lower extremity proximal muscle strength (chair stands), impaired balance (three

2020 Experimental Gerontology

105. The medical costs of low leisure-time physical activity among working-age adults: Gender and minority status matter. (Abstract)

The medical costs of low leisure-time physical activity among working-age adults: Gender and minority status matter. This study analyzes the direct medical costs of low physical activity by race/ethnicity and gender. Average health expenditures based on physical activity status for Black non-Hispanics (NH), Asian NHs, and Hispanics were compared to White NHs. Data from the National Health Interview Survey were merged with the Medical Expenditure Panel Survey for years 2000-2010 and 2001-2011 (...) , respectively, and weights were applied to ensure generalizability to the larger US population. The sample was restricted to non-pregnant adults between the ages of 25 and 64, with a final sample size of 44,953. The multivariate estimates reveal statistically significant lower annual health care expenditures among physically active men and women in five out of eight racial/ethnic groups relative to their inactive counterparts: on average, for men, $1041 less is spent among White NHs, $905 less is spent

2020 Preventive Medicine

106. Medical home effects on enrollees with mental and physical illness. (Abstract)

Medical home effects on enrollees with mental and physical illness. To assess the effect of medical home enrollment on acute care use and healthcare spending among Medicaid beneficiaries with mental and physical illness.Retrospective cohort analysis of administrative data.We used 2007-2010 Medicaid claims and state psychiatric hospital data from a sample of 83,819 individuals diagnosed with schizophrenia or depression and at least 1 comorbid physical condition. We performed fixed-effects (...) visits (P <.05). Medical home enrollment was associated with an increase in mean monthly spending among those with schizophrenia ($65.8; P <.05) and a decrease among those with depression (-$66.4; P <.05).Among Medicaid beneficiaries with comorbid mental and physical illness, medical home enrollment appears to increase outpatient healthcare use and has mixed effects on acute care use. For individuals in this population who previously had no engagement with the healthcare system, use of the medical

2020 American Journal Of Managed Care

107. Effectiveness of a multifactorial intervention, consisting of self-management of antihypertensive medication, self-measurement of blood pressure, hypocaloric and low sodium diet, and physical exercise, in patients with uncontrolled hypertension taking 2 o Full Text available with Trip Pro

), controled, cluster-randomized clinical trial. General practitioners and nurses will be randomly allocated to the intervention group (self-management of antihypertensive medication, self-measurement of blood pressure, hypocaloric and low sodium diet, and physical exercise) or the control group (regular clinical practice). A total of 424 patients in primary care centers who use 2 or more antihypertensive drugs and blood pressure of at least 130/80 during 24-hambulatory blood pressure monitoring (...) Effectiveness of a multifactorial intervention, consisting of self-management of antihypertensive medication, self-measurement of blood pressure, hypocaloric and low sodium diet, and physical exercise, in patients with uncontrolled hypertension taking 2 o High blood pressure is the leading modifiable risk factor for cardiovascular disease, and is associated with high morbidity and mortality and with significant health care costs for individuals and society. However, fewer than half

2020 Medicine

108. Clinical osteoarthritis of the hip and knee and fall risk: The role of low physical functioning and pain medication. Full Text available with Trip Pro

Clinical osteoarthritis of the hip and knee and fall risk: The role of low physical functioning and pain medication. Several studies have found an increased fall risk in persons with osteoarthritis (OA). However, most prospective studies did not use a clinical definition of OA. In addition, it is not clear which factors explain this risk. Our objectives were: (1) to confirm the prospective association between clinical OA of the hip and knee and falls; (2) to examine the modifying effect of sex (...) ; and (3) to examine whether low physical performance, low physical activity and use of pain medication are mediating these relationships.Baseline and 1-year follow-up data from the European Project on OSteoArthritis (EPOSA) were used involving pre-harmonized data from five European population-based cohort studies (ages 65-85, n = 2535). Clinical OA was defined according to American College of Rheumatology (ACR) criteria. Falls were assessed using self-report.Over the follow-up period, 27.7

2020 Seminars in arthritis and rheumatism

109. The effect of exercise and motor interventions on physical activity and motor outcomes during and after medical intervention for children and adolescents with acute lymphoblastic leukemia: A systematic review. (Abstract)

The effect of exercise and motor interventions on physical activity and motor outcomes during and after medical intervention for children and adolescents with acute lymphoblastic leukemia: A systematic review. Children with acute lymphoblastic leukemia (ALL) experience detrimental effects on motor function during and after chemotherapy. The objective of this systematic review was to evaluate the effect of exercise and motor interventions on physical activity and motor outcomes of children (...) with ALL during and after chemotherapy.Ten databases were searched. Nineteen studies were included: 11 randomized clinical trials (RCT), 2 controlled clinical trials (CCT), and 6 cohort studies.Participants included 508 children with ALL. Between-group results from RCTs and CCTs supported that exercise and motor intervention improved: fatigue during acute chemotherapy; physical activity, range of motion (ROM), strength, bone mineral density, aerobic capacity, and fatigue during maintenance chemotherapy

2020 Critical reviews in oncology/hematology

110. Accelerometry assessed physical activity of older adults hospitalized with acute medical illness - an observational study. Full Text available with Trip Pro

Accelerometry assessed physical activity of older adults hospitalized with acute medical illness - an observational study. In a hospital setting and among older patients, inactivity and bedrest are associated with a wide range of negative outcomes such as functional decline, increased risk of falls, longer hospitalization and institutionalization. Our aim was to assess the distribution, determinants and predictors of physical activity (PA) levels using wrist-worn accelerometers in older (...) patients hospitalized with acute medical illness.Observational study conducted from February to November 2018 at an acute internal medicine unit in the University hospital of Lausanne, Switzerland. We enrolled 177 patients aged ≥65 years, able to walk prior to admission. PA during acute hospital stay was continuously recorded via a 3D wrist accelerometer. Clinical data was collected from medical records or by interview. Autonomy level prior to inclusion was assessed using Barthel Index score. PA levels

2020 BMC Geriatrics

111. Demographic and health-related factors associated with reduced work functioning in people with moderate medically unexplained physical symptoms: a cross-sectional study. Full Text available with Trip Pro

Demographic and health-related factors associated with reduced work functioning in people with moderate medically unexplained physical symptoms: a cross-sectional study. Medically unexplained physical symptoms (MUPS) are a leading cause of reduced work functioning. It is not known which factors are associated with reduced work functioning in people with moderate MUPS. Insight in these factors can contribute to prevention of reduced work functioning, associated work-related costs and in MUPS (...) symptoms (four domains, measured with the Four-Dimensional Symptom Questionnaire), physical health (RAND 36-Item Health Survey), moderate or vigorous physical activity (Activ8 activity monitor), age, sex, education level and duration of complaints. Two separate multivariable linear regression analyses were performed with backward stepwise selection, for both impaired work performance and absenteeism.Absenteeism rate rose with 2.5 and 0.6% for every increased point on the Four-Dimensional Symptom

2020 BMC Public Health

112. The effects of emergency medical service work on the psychological, physical, and social well-being of ambulance personnel: a systematic review of qualitative research. Full Text available with Trip Pro

The effects of emergency medical service work on the psychological, physical, and social well-being of ambulance personnel: a systematic review of qualitative research. High rates of mental distress, mental illness, and the associated physical effects of psychological injury experienced by ambulance personnel has been widely reported in quantitative research. However, there is limited understanding of how the nature of ambulance work contributes to this problem, the significant large toll (...) that emergency medical response takes on the individual, and particularly about late and cumulative development of work-related distress among this first responder workforce.This study examined peer-reviewed qualitative research published from 2000 to 2018 to outline the effect of emergency medical response work on the psychological, psychosocial, and physical health of paramedics, ambulance officers, ambulance volunteers, and call-takers. Databases searched included: Ovid Medline, CINAHL, Ovid EMcare

2020 BMC Psychiatry

113. Radiation dose monitoring software for medical imaging with ionising radiation

: directly from the imaging device using the picture archiving and communication system (PACS), a technology that stores and handles medical images and related information or or from the radiology information system. The software uses digital imaging and communications in medicine (DICOM)-standard data sources to gather information relating to the radiation dose. DICOM (National Electrical Manufacturers Association) is an international standard used in the NHS for storing and exchanging medical images (...) physicist, Guy's and St Thomas' NHS Foundation Trust. No relevant conflicts of interest. Dr Giles Roditi, consultant radiologist, NHS Greater Glasgow and Clyde. No relevant conflicts of interest. Andy Rogers, medical physicist, Nottingham University Hospitals NHS Trust. Mr Rogers is a member of the Philips Healthcare DoseWise Medical Physics Advisory Board, whose payments support his research activities and professional development. Dr Arun Sebastian, consultant radiologist, Colchester Hospital

2017 National Institute for Health and Clinical Excellence - Advice

114. Implementation of the Goal-directed Medication review Electronic Decision Support System (G-MEDSS)© into home medicines review: a protocol for a cluster-randomised clinical trial in older adults. Full Text available with Trip Pro

Implementation of the Goal-directed Medication review Electronic Decision Support System (G-MEDSS)© into home medicines review: a protocol for a cluster-randomised clinical trial in older adults. Older people living in the community have a high prevalence of polypharmacy and are vulnerable to adverse drug events. Home Medicines Review (HMR) is a collaborative medication review service involving general practitioners (GPs), accredited clinical pharmacists (ACPs) and patients, which aims (...) intervention in HMR. Community-dwelling older adults living with and without dementia who are referred for HMR by their GP and recruited by ACPs will be included in this study. G-MEDSS is a CCDSS designed to provide clinical decision support for healthcare practitioners when completing a medication review, to tailor care to meet the patients' goals and preferences. The G-MEDSS contains three tools: The Goals of Care Management Tool, The Drug Burden Index (DBI) Calculator©, and The revised Patients

2020 BMC Geriatrics

115. Russian Federation medical student knowledge, attitudes and beliefs toward medical cannabis. (Abstract)

, Russian university medical students tend to reflect negative attitudes and beliefs toward MC. Female students were more inclined to recommend MC for patient treatment and its legalization; and, believe it is not addictive and does not pose physical or mental health risk. Students who support MC use believe it has treatment benefits, support additional research as well as policy change for its legalization. Secular, more than religious, students report more positive attitudes toward MC use. About 34 (...) Russian Federation medical student knowledge, attitudes and beliefs toward medical cannabis. To assess medical student knowledge, attitudes and beliefs about cannabis use for medical conditions in Russia where it is prohibited.This study uses data collected from 463 Russian origin medical students. Pearson Chi-square test for categorical variables was used to determine whether student knowledge, attitudes and beliefs of medical cannabis (MC) are affected by gender and religiosity.Overall

2020 Complementary Therapies In Medicine

116. Effects of medical and non-medical cannabis use in older adults: protocol for a scoping review. Full Text available with Trip Pro

and higher use rates. However, older adults experience slower metabolism, increased likelihood of polypharmacy, cognitive decline and chronic physical/mental health problems. There is a need to enhance knowledge of the effects of cannabis use in older adults. The following question will be addressed using a scoping review approach: what evidence exists regarding beneficial and harmful effects of medical and non-medical cannabis use in adults >50 years of age? Given that beneficial and harmful effects (...) Effects of medical and non-medical cannabis use in older adults: protocol for a scoping review. With its legalisation and regulation in Canada in 2018, the proportion of Canadians reporting cannabis use in 2019 increased substantially over the previous year, with half of new users being aged 45+ years. While use in older adults has been low historically, as those born in the 1950s and 1960s continue to age, this demographic will progressively have more liberal attitudes, prior cannabis exposure

2020 BMJ open

117. Adaptive pacing, cognitive behaviour therapy, graded exercise, and specialist medical care for chronic fatigue syndrome: a cost-effectiveness analysis Full Text available with Trip Pro

Adaptive pacing, cognitive behaviour therapy, graded exercise, and specialist medical care for chronic fatigue syndrome: a cost-effectiveness analysis Adaptive pacing, cognitive behaviour therapy, graded exercise, and specialist medical care for chronic fatigue syndrome: a cost-effectiveness analysis Adaptive pacing, cognitive behaviour therapy, graded exercise, and specialist medical care for chronic fatigue syndrome: a cost-effectiveness analysis McCrone P, Sharpe M, Chalder T, Knapp M (...) -pacing therapy, cognitive behavioural therapy (CBT), or graded-exercise therapy to specialist medical care for adult patients with chronic fatigue syndrome in the UK from two alternative perspectives (health care and societal). Interventions Four alternatives were compared: specialist medical care (at least three sessions) plus CBT (at least 15 individual therapy sessions); 2) specialist medical care (at least three sessions) plus graded-exercise therapy (up to 15 sessions); specialist medical care

2013 NHS Economic Evaluation Database.

118. Physical health and drug safety in individuals with schizophrenia Full Text available with Trip Pro

Physical health and drug safety in individuals with schizophrenia While antipsychotic medications are the mainstay of therapy for individuals with schizophrenia and psychotic disorders, their use is associated with adverse effects on physical health that require the attention and care of prescribers.We used the ADAPTE process to adapt existing guideline recommendations from the National Institute for Health and Care Excellence (NICE) and Scottish Intercollegiate Guidelines Network (SIGN (...) interventions are recommended to mitigate antipsychotic-induced weight gain. Prescribers should follow Canadian guidelines on the treatment of obesity, dyslipidemia, and diabetes. Recommendations on antipsychotic drug choice are made for users particularly concerned about extrapyramidal symptoms.Careful monitoring and attention by prescribers may mitigate adverse effects associated with antipsychotic medications.

2017 CPG Infobase

119. Characteristics of Professional Physical Therapist Faculty and Doctor of Physical Therapy Programs, 2008-2017: Influences on Graduation Rates and First-Time National Physical Therapy Examination Pass Rates. (Abstract)

Characteristics of Professional Physical Therapist Faculty and Doctor of Physical Therapy Programs, 2008-2017: Influences on Graduation Rates and First-Time National Physical Therapy Examination Pass Rates. Graduation rates and first-time National Physical Therapy Examination (NPTE) pass rates among Doctor of Physical Therapy (DPT) programs have ranged from 30% to 100% and 0% to 100% between 2008 and 2017, respectively. Prior studies on predictors of graduation rates and NPTE pass rates from (...) , as the predicted rates of decline in pass rates were minimal.Faculty engagement in scholarly activities may positively influence graduation rates, but only up to a certain level of faculty time devoted to scholarship.This is the first study to provide data on the influence of faculty on DPT student outcomes and will help education programs develop strategies to improve those outcomes.© The Author(s) 2020. Published by Oxford University Press on behalf of the American Physical Therapy Association. All rights

2020 Physical therapy

120. Slowing down glioblastoma progression in mice by running or the anti-malarial drug dihydroartemisinin? Induction of oxidative stress in murine glioblastoma therapy Full Text available with Trip Pro

Slowing down glioblastoma progression in mice by running or the anti-malarial drug dihydroartemisinin? Induction of oxidative stress in murine glioblastoma therapy Influencing cancer metabolism by lifestyle changes is an attractive strategy as - if effective - exercise-induced problems may be less severe than those induced by classical anti-cancer therapies. Pursuing this idea, clinical trials evaluated the benefit of e.g. different diets such as the ketogenic diet, intermittent caloric (...) restriction and physical exercise (PE) in the primary and secondary prevention of different cancer types. PE proved to be beneficial in the context of breast and colon cancer.Glioblastoma has a dismal prognosis, with an average overall survival of about one year despite maximal safe resection, concomitant radiochemotherapy with temozolomide followed by adjuvant temozolomide therapy. Here, we focused on the influence of PE as an isolated and adjuvant treatment in murine GB therapy.PE did not reduce toxic

2016 Oncotarget

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