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Photorefractive Keratectomy

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181. Pregabalin Versus Placebo in Postoperative Pain Relief of Patients' Status Post Photorefractive Keratectomy: A Double-Masked, Randomized, Prospective Study. (PubMed)

Pregabalin Versus Placebo in Postoperative Pain Relief of Patients' Status Post Photorefractive Keratectomy: A Double-Masked, Randomized, Prospective Study. Gabapentinoids are currently being used anecdotally for postoperative pain following photorefractive keratectomy (PRK) despite the lack of evidence. The purpose of this study is to evaluate the effectiveness of pregabalin in mitigating pain after PRK compared to the standard of care.One hundred thirty-five patients scheduled for PRK

2014 Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics Controlled trial quality: predicted high

182. Prospective, randomized, contralateral eye comparison of tetracaine and proparacaine for pain control in laser in situ keratomileusis and photorefractive keratectomy. (PubMed)

Prospective, randomized, contralateral eye comparison of tetracaine and proparacaine for pain control in laser in situ keratomileusis and photorefractive keratectomy. Tetracaine and proparacaine are two of the most commonly used medications for providing topical anesthesia in laser in situ keratomileusis (LASIK) and photorefractive keratectomy (PRK). These agents have not been previously compared in a prospective manner to determine their efficacy in these settings.This prospective, single

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2014 Clinical ophthalmology (Auckland, N.Z.) Controlled trial quality: uncertain

183. The Effect of Silicone Hydrogel Bandage Soft Contact Lens Base Curvature on Comfort and Outcomes After Photorefractive Keratectomy. (PubMed)

The Effect of Silicone Hydrogel Bandage Soft Contact Lens Base Curvature on Comfort and Outcomes After Photorefractive Keratectomy. To evaluate the relative pain and the relative amount of contact lens loss experienced using two different base curvatures (BCs) of the Acuvue Oasys bandage soft contact lens (BSCL) after photorefractive keratectomy (PRK).One hundred forty patients undergoing PRK on either the Allegretto or the VISX laser at the Joint Warfighter Refractive Surgery Center

2014 Eye & contact lens Controlled trial quality: uncertain

184. Effect of topical diclofenac on postoperative photorefractive keratectomy pain: a randomized controlled trial. (PubMed)

Effect of topical diclofenac on postoperative photorefractive keratectomy pain: a randomized controlled trial. A major disadvantage of photorefractive keratectomy is postoperative pain and discomfort. This study aims to evaluate whether topical diclofenac 0.1% therapy adds any extra benefit to systemic diclofenac in controlling pain after photorefractive keratectomy.Prospective randomized, double-masked clinical trial applied in the Khatam-al-Anbia Eye Hospital, Mashhad University of Medical (...) Sciences, Mashhad, Iran.Sixty-eight individuals (age range, 18-35 years) having bilateral photorefractive keratectomy for myopic correction with or without astigmatism.All patients received 100 mg of extended-release oral diclofenac two times (12-h interval) before photorefractive keratectomy surgery. Postoperatively, patients were randomized into the case and control groups. Case group was administered the diclofenac 0.1% drop, one drop 2 h preoperatively and four times daily postoperatively for 3

2014 Clinical & experimental ophthalmology Controlled trial quality: uncertain

185. Prospective randomized contralateral eye evaluation of subjective quality of vision after wavefront-guided or wavefront- optimized photorefractive keratectomy. (PubMed)

Prospective randomized contralateral eye evaluation of subjective quality of vision after wavefront-guided or wavefront- optimized photorefractive keratectomy. To compare the effect of wavefront-guided (WFG) and wavefront-optimized (WFO) photorefractive keratectomy (PRK) on patient perceived quality of vision.Seventy-one patients (142 eyes) were enrolled in this prospective, randomized, fellow eye controlled study. One eye was randomized to undergo WFG PRK treatment by the AMO Visx CustomVue S4

2014 Journal of Refractive Surgery Controlled trial quality: uncertain

186. Effect of the combination of basic fibroblast growth factor and cysteine on corneal epithelial healing after photorefractive keratectomy in patients affected by myopia. (PubMed)

Effect of the combination of basic fibroblast growth factor and cysteine on corneal epithelial healing after photorefractive keratectomy in patients affected by myopia. This study sought to evaluate the effect of basic fibroblast growth factor eye drops and cysteine oral supplements on corneal healing in patients treated with photorefractive keratectomy (PRK).One hundred and twenty patients treated bilaterally with PRK for myopia were enrolled at one of two eye centers (Clinica Santa Lucia

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2014 Indian journal of ophthalmology Controlled trial quality: uncertain

187. Ascorbic acid versus placebo in postoperative lid edema postphotorefractive keratectomy: A double-masked, randomized, prospective study. (PubMed)

Ascorbic acid versus placebo in postoperative lid edema postphotorefractive keratectomy: A double-masked, randomized, prospective study. Photorefractive keratectomy (PRK) is a proper type of refractive surgery used to remodel corneal stroma to compensate refractive errors. Corneal haze was reported as one of the side effects in several studies. This study was conducted for investigation of the effect of preventive effect of Vitamin C on eyelid edema, corneal haze, corneal epithelial healing

2019 Oman journal of ophthalmology Controlled trial quality: uncertain

188. Clinical presentation following photorefractive intrastromal cross-linking for myopic correction (PubMed)

, Coimbatore, Tamil Nadu, India. eng Case Reports Journal Article India Indian J Ophthalmol 0405376 0301-4738 0 Cross-Linking Reagents IM Corneal Stroma diagnostic imaging drug effects surgery Corneal Topography Cross-Linking Reagents administration & dosage Female Humans Lasers, Excimer therapeutic use Myopia diagnosis physiopathology therapy Photochemotherapy methods Photorefractive Keratectomy methods Refraction, Ocular Tomography, Optical Coherence Young Adult Collagen cross-linking myopia (...) Clinical presentation following photorefractive intrastromal cross-linking for myopic correction 29941747 2018 07 16 2018 11 14 1998-3689 66 7 2018 07 Indian journal of ophthalmology Indian J Ophthalmol Clinical presentation following photorefractive intrastromal cross-linking for myopic correction. 993-994 10.4103/ijo.IJO_1227_17 Sachdev Gitansha Shreyas GS Refractive Services, The Eye Foundation, Coimbatore, Tamil Nadu, India. Ramamurthy Shreyas S Refractive Services, The Eye Foundation

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2018 Indian journal of ophthalmology

189. Comparison of laser epithelial keratomileusis and photorefractive keratectomy for the correction of myopia: a meta-analysis

Comparison of laser epithelial keratomileusis and photorefractive keratectomy for the correction of myopia: a meta-analysis Comparison of laser epithelial keratomileusis and photorefractive keratectomy for the correction of myopia: a meta-analysis Comparison of laser epithelial keratomileusis and photorefractive keratectomy for the correction of myopia: a meta-analysis Cui M, Chen XM, Lu P CRD summary The review concluded that there was no definitive evidence that laser epithelial (...) keratomileusis (LASEK) was better than photorefractive keratectomy (PRK) for correcting myopia from 0 to -9.0 dioptres. The review had some methodological weaknesses, but the authors’ conclusion is likely to be reliable given the evidence available. Authors' objectives To compare the efficacy, accuracy, safety and side-effects of laser epithelial keratomileusis (LASEK) and photorefractive keratectomy (PRK) for the correction of myopia. Searching PubMed, EMBASE, Chinese Bio-medicine Database and Cochrane

2008 DARE.

190. Laser-assisted subepithelial keratectomy and photorefractive keratectomy for post-penetrating keratoplasty myopia and astigmatism in adults. (PubMed)

Laser-assisted subepithelial keratectomy and photorefractive keratectomy for post-penetrating keratoplasty myopia and astigmatism in adults. To evaluate whether laser-assisted subepithelial keratectomy (LASEK) and photorefractive keratectomy (PRK) achieve effective targeted correction and the extent of post-treatment corneal haze after corneal transplantation.Nonhospital surgical facility, Calgary, Alberta, Canada.Evidence-based manuscript.This study evaluated visual acuity, refractive error

2011 Journal of cataract and refractive surgery

191. Rapamycin Inhibits the Production of Myofibroblasts and Reduces Corneal Scarring after Photorefractive Keratectomy. (PubMed)

Rapamycin Inhibits the Production of Myofibroblasts and Reduces Corneal Scarring after Photorefractive Keratectomy. Corneal stromal scarring partly involves the production of corneal myofibroblasts. The purpose of this study was to examine the effects of rapamycin (an inhibitor of the mammalian target of rapamycin [mTOR] pathway) on myofibroblast formation in vitro and in-vivo.Human corneal fibroblasts were grown in culture and transformed into myofibroblasts using TGF-β (2 ng/mL

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2013 Investigative Ophthalmology & Visual Science

192. Laser-assisted in-situ keratomileusis (LASIK) versus photorefractive keratectomy (PRK) for myopia. (PubMed)

Laser-assisted in-situ keratomileusis (LASIK) versus photorefractive keratectomy (PRK) for myopia. Myopia (also known as short-sightedness or near-sightedness) is an ocular condition in which the refractive power of the eye is greater than is required, resulting in light from distant objects being focused in front of the retina instead of directly on it. The two most commonly used surgical techniques to permanently correct myopia are photorefractive keratectomy (PRK) and laser-assisted in-situ

2013 Cochrane database of systematic reviews (Online)

193. Impact of Keratoconus, Cross-linking and Cross-linking Combined With Topo-guided Photorefractive Keratectomy on Self-reported Quality of Life. A Three-year Update.

Impact of Keratoconus, Cross-linking and Cross-linking Combined With Topo-guided Photorefractive Keratectomy on Self-reported Quality of Life. A Three-year Update. Impact of Keratoconus, Cross-linking and Cross-linking Combined With Topo-guided Photorefractive Keratectomy on Self-reported Quality of Life. A Three-year Update. - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x (...) × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Impact of Keratoconus, Cross-linking and Cross-linking Combined With Topo-guided Photorefractive Keratectomy on Self-reported Quality of Life. A Three-year Update. The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated

2013 Clinical Trials

194. Photorefractive keratectomy in patients with suspected keratoconus: five-year follow-up. (PubMed)

Photorefractive keratectomy in patients with suspected keratoconus: five-year follow-up. To assess the long-range outcomes of photorefractive keratectomy (PRK) using functional and topographic criteria in myopic eyes with suspected keratoconus.Rothschild Foundation, Paris, France.Retrospective interventional case series.Eyes of patients classified as keratoconus suspects or keratoconus by the Corneal Navigator software of the OPD-Scan II device were included. They were treated with myopic PRK (...) , 45.75 ± 1.75 D. The percentage of similarity to keratoconus suspects or keratoconus was positive in all 62 eyes and exceeded a 50% similarity score in 30 eyes (48.4%). The mean follow-up was 4.8 ± 1.4 years. The mean magnitude of the SE was -0.53 ± 1.35 D over the follow-up. Two patients required glasses postoperatively because of significant myopic regression. No case of corneal ectasia was reported.Photorefractive keratectomy in eyes with suspected keratoconus based on a Placido neural network may

2013 Journal of cataract and refractive surgery

195. Topography-guided transepithelial photorefractive keratectomy for irregular astigmatism using a 213 nm solid-state laser. (PubMed)

Topography-guided transepithelial photorefractive keratectomy for irregular astigmatism using a 213 nm solid-state laser. To explore the use of the Pulsar Z1 solid-state 213 nm photorefractive laser platform in topography-guided transepithelial photorefractive keratectomy (PRK) for irregular astigmatism.Moorfields Eye Hospital, London, United Kingdom.Prospective clinical case series.Patients with irregular astigmatism after previous refractive surgery or corneal transplantation were treated

2013 Journal of cataract and refractive surgery

196. Central corneal haze after wedge resection following penetrating keratoplasty and photorefractive keratectomy (PubMed)

Central corneal haze after wedge resection following penetrating keratoplasty and photorefractive keratectomy 23449513 2013 11 18 2018 11 13 1476-5454 27 5 2013 May Eye (London, England) Eye (Lond) Central corneal haze after wedge resection following penetrating keratoplasty and photorefractive keratectomy. 679-80 10.1038/eye.2013.27 Pöschl E Maria EM El-Shabrawi Y Y Ardjomand N N eng Case Reports Letter 2013 03 01 England Eye (Lond) 8703986 0950-222X IM Adult Corneal Opacity etiology Humans (...) Keratoconus surgery Keratoplasty, Penetrating adverse effects Male Photorefractive Keratectomy adverse effects 2013 3 2 6 0 2013 3 2 6 0 2013 11 19 6 0 ppublish 23449513 eye201327 10.1038/eye.2013.27 PMC3650274 Ophthalmology. 2000 Jan;107(1):89-94 10647725 J Refract Surg. 1999 Jan-Feb;15(1):53-7 9987724 J Refract Surg. 2003 Sep-Oct;19(5):560-5 14518745

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2013 Eye

197. Comparison of standard and low dose intraoperative mitomycin C in prevention of corneal hazeafter photorefractive keratectomy. (PubMed)

Comparison of standard and low dose intraoperative mitomycin C in prevention of corneal hazeafter photorefractive keratectomy. This study aimed to compare two doses of Mitomycin C in reducing haze formation after photorefractive keratectomy.170 eyes of 85 patients enrolled; in each patient one eye randomly assigned to be treated by low dose intraoperative MMC (LDMMC) and other eye by standard dose MMC (SDMMC). Then the patients were followed up to 6 months and refraction, Uncorrected Distant

2013 International journal of preventive medicine Controlled trial quality: uncertain

198. Topical cyclosporine A for postoperative photorefractive keratectomy and laser in situ keratomileusis. (PubMed)

Topical cyclosporine A for postoperative photorefractive keratectomy and laser in situ keratomileusis. To compare the stability and predictability of the refractive outcomes in eyes treated with photorefractive keratectomy (PRK) or laser in situ keratomileusis (LASIK) with and without postoperative use of topical cyclosporine A emulsion.Naval Medical Center San Diego Refractive Surgery Center, San Diego, California, USA.Randomized clinical trial.Patients had PRK or LASIK and were randomized

2013 Journal of cataract and refractive surgery Controlled trial quality: uncertain

199. Randomized dose-response analysis of mitomycin-C to prevent haze after photorefractive keratectomy for high myopia. (PubMed)

Randomized dose-response analysis of mitomycin-C to prevent haze after photorefractive keratectomy for high myopia. To evaluate the safety and efficacy of mitomycin-C (MMC) 0.01% (0.1 mg/mL) in preventing haze formation after wavefront-guided photorefractive keratectomy (PRK) for higher myopia at 3 exposures.United States Navy Refractive Surgery Center, San Diego, California, USA.Double-masked randomized prospective trial.Sixty-, 30-, and 15-second exposures of MMC 0.01% were compared

2013 Journal of cataract and refractive surgery Controlled trial quality: uncertain

200. The effects of mitomycin C on tear function after photorefractive keratectomy: a contralateral comparative study. (PubMed)

The effects of mitomycin C on tear function after photorefractive keratectomy: a contralateral comparative study. To assess the effects of adjuvant mitomycin C (MMC) on tear function tests after photorefractive keratectomy (PRK) for myopia.In this prospective, randomized, double-blind study, one eye of myopic patients undergoing PRK was randomly chosen for PRK and the other eye was treated with PRK plus the application of 0.02% MMC for 20 seconds onto the ablated stroma. All patients had

2013 Journal of Refractive Surgery Controlled trial quality: uncertain

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