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Pharyngitis Causes

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161. The Addition of a Head Rotation When the Ramped Position Fails to Provide Good Laryngeal Visualization: A Preliminary Study Full Text available with Trip Pro

in 62 patients. The method significantly improved laryngeal visualization and did not cause laryngeal disturbances postoperatively. (...) The Addition of a Head Rotation When the Ramped Position Fails to Provide Good Laryngeal Visualization: A Preliminary Study Although several studies have reported that the ramped position (torso and head elevated) significantly improves laryngoscopic view, in our experience, the ramped position fails to provide good laryngeal visualization in some cases. When the ramped position failed to provide good laryngeal visualization, we added a head rotation in order to improve laryngeal visualization

2018 Anesthesiology and pain medicine

162. False-Positive Laryngeal FDG Uptake During PET/CT Imaging: Reinke’s Edema Full Text available with Trip Pro

, is asymmetrically increased. We reported the first case of histologically proven Reinke's edema causing false-positive laryngeal FDG uptake on PET/CT imaging. A clinician must be aware of these rare benign lesions in the case of increased FDG uptake, and histopathological investigation is mandatory to rule out malignancy for suspicious cases. (...) False-Positive Laryngeal FDG Uptake During PET/CT Imaging: Reinke’s Edema Positron emission tomography/computed tomography (PET/CT) is frequently used for diagnosing, staging, and following-up various malignancy types because it provides information on the site and metabolic activity of the tumor. Fluorodeoxyglucose (FDG) uptake by the normal laryngeal tissue is symmetric and low, whereas that under some non-malignant conditions of the larynx, such as vocal cord paralysis and Teflon granuloma

2018 Turkish Archives of Otorhinolaryngology

163. Integrin β1 regulates the invasion and radioresistance of laryngeal cancer cells by targeting CD147 Full Text available with Trip Pro

. The invasion ability of laryngeal cancer cells was detected by transwell and wound healing assays. The radiosensitivity of laryngeal cancer cells was evaluated by flow cytometry and colony formation assays.High expression of integrin β1 was significantly associated with lymph node metastasis, TNM stage and poor clinical outcomes (all p < 0.05). Knockdown of integrin β1 in laryngeal cancer cells inhibited invasion and increased radiosensitivity. Mechanistically, these effects were caused by suppression (...) Integrin β1 regulates the invasion and radioresistance of laryngeal cancer cells by targeting CD147 Increased expression of integrin β1 has been reported to correlate with progression and therapy resistance in many types of cancers. The aim of this study was to investigate the effects of integrin β1 on the invasion and radioresistance of laryngeal cancer cells.The expression of integrin β1 in the tumor specimens of laryngeal cancer patients was assessed by immunohistochemical assays

2018 Cancer cell international

164. Comparing the safety of harmonic ACE and ACE+ around the recurrent laryngeal nerve in swine models Full Text available with Trip Pro

Comparing the safety of harmonic ACE and ACE+ around the recurrent laryngeal nerve in swine models Among the various energy-based devices, ultrasonic shears are popular in thyroid surgeries. In this study, we tested the safety of Harmonic ACE and Harmonic ACE+ around the recurrent laryngeal nerve (RLN) in experimental swine models.Harmonic ACE and Harmonic ACE+ were each tested in 4 piglets. Harmonic ACE and Harmonic ACE+ were activated at a 0- to 5-mm distance from the RLN. The function (...) EMG event observed when activated at 1- and 3-mm distances from the RLN. At a 0-mm distance, 2 adverse EMG events occurred after 6 to 10 seconds of activation.The safe distance of Harmonic ACE and ACE+ was 4 and 1 mm, respectively, in the swine models. Harmonic ACE+ is safer than Harmonic ACE because it did not cause any tissue shrinkage. Surgeons need to understand the characteristics of devices for safe operation.

2018 Annals of surgical treatment and research

165. Incidence and mortality of laryngeal cancer in China, 2008–2012 Full Text available with Trip Pro

and it was the 21st cause of cancer-related death in overall cancers. Both the age-standardized mortality rates by Chinese standard population (ASMRC) and by world standard population (ASMRW) were 0.63/100,000. Incidence and mortality rates of laryngeal cancer were higher in males than in females and higher in urban areas than in rural areas. Middle areas had the highest incidence and mortality rates followed by eastern and western areas. Incidence and mortality rates of laryngeal cancer retained low level before (...) Incidence and mortality of laryngeal cancer in China, 2008–2012 To analyze the incidence and mortality rates of laryngeal cancer in China from 2008 to 2012.Incident and death cases of laryngeal cancer were retrieved from the National Central Cancer Registry (NCCR) database collecting from 135 cancer registries in China during 2008-2012. The crude incidence and mortality rates of laryngeal cancer were calculated by area (urban/rural), region (eastern, middle, western), gender and age group (0

2018 Chinese Journal of Cancer Research

166. Clinical application of limiting laryngeal mask airway cuff pressures utilizing inflating syringe intrinsic recoil Full Text available with Trip Pro

Clinical application of limiting laryngeal mask airway cuff pressures utilizing inflating syringe intrinsic recoil Overinflation of the laryngeal mask airway (LMA) cuff may cause many of the complications associated with the use of the LMA. There is no clinically acceptable (cost effective and practical) method to ensure cuff pressure is maintained below the manufacturer's recommended maximum value of 60 cm H2O (44 mmHg). We studied the use of the intrinsic recoil of the LMA inflating syringe (...) the pressure transducer group and the syringe recoil group for initial cuff pressure or cuff pressure 1 hour after surgery. Both the syringe recoil group and pressure transducer group were less likely than the standard practice group to have sore throat and dysphagia 1 hour after surgery. These differences remained 24 hours after surgery.Syringe recoil provides an efficient and reproducible method similar to manometry in preventing overinflation of the LMA cuff and decreasing the incidence of postoperative

2018 Romanian Journal of Anaesthesia and Intensive Care

167. Recurrent laryngeal nerve reinnervation for management of aspiration in a subset of children. (Abstract)

Recurrent laryngeal nerve reinnervation for management of aspiration in a subset of children. Pediatric aspiration is a multifactorial process that is often complex to manage. Recurrent laryngeal nerve (RLN) injury can cause glottic insufficiency and aspiration. We describe three cases of unilateral vocal fold paralysis resulting in aspiration and the successful use of the RLN reinnervation for its treatment. The theory for utilizing the reinnervation procedure is that when glottic closure

2018 International Journal of Pediatric Otorhinolaryngology

168. The management of laryngeal lipoid proteinosis. (Abstract)

The management of laryngeal lipoid proteinosis. Lipoid proteinosis is a rare autosomal recessive disorder caused by mutations in the extracellular matrix protein 1 gene. It is characterised by deposition of hyaline material in the skin and mucous membranes. This paper describes the management of two cases with laryngopharyngeal disease.Two patients with a biopsy diagnosis of lipoid proteinosis were identified from the surgical pathology archive covering the period 2004-2016. Their notes were (...) with interval laser debulking and the 'pepper pot' technique without causing stenosis.

2018 Journal of Laryngology & Otology

169. Compound Motor Action Potential Measures Acute Changes in Laryngeal Innervation. (Abstract)

Compound Motor Action Potential Measures Acute Changes in Laryngeal Innervation. Vocal fold paralysis is caused by injury to the recurrent laryngeal nerve (RLN). Current clinical measures of laryngeal innervation are often nonquantitative. Compound motor action potentials (CMAP) measure motor innervation. The goal of this study was to determine whether CMAP can quantify laryngeal innervation following acute nerve injury.Animal study.Twelve canine hemilaryngeal preparations were used. The RLN

2018 Rhinology and Laryngology

170. Laryngeal Vibration for Spasmodic Dysphonia

of the vibration is similar to the vibration experienced from vibrating cell phones or gaming joysticks. Vibro-tactile stimulation at the applied frequency and amplitude is not known to cause pain or tissue damage. The participant may feel a mild tingling or vibrating sensation. Preliminary testing on healthy human subjects showed that at the given vibration parameters no adverse reactions occur. Experimental: High-Low Treatment Participants in the high-low treatment group will receive Laryngeal Vibration (...) (Treatment) at 100Hz frequency every second day of the week for a duration of 4 weeks (high intensity). Then they will switch and receive laryngeal vibration at 100Hz frequency once a week for a duration of 4 weeks (low intensity). Device: Laryngeal Vibration (Treatment) The strength of the vibration is similar to the vibration experienced from vibrating cell phones or gaming joysticks. Vibro-tactile stimulation at the applied frequency and amplitude is not known to cause pain or tissue damage

2018 Clinical Trials

171. Nomograms to Precisely Predict Conditional Risk of Survival for Patients With Laryngeal Cancer

or persistent laryngeal SCC after definitive RT/CRT who has undergone total laryngectomy in order to identify potential preoperative predictors of clinical outcomes. Condition or disease Intervention/treatment Laryngeal Cancer Procedure: Radical Operation Detailed Description: Demographic, clinical, and survival data were abstracted. Death was verified via medical records and the social security death index. Primary outcome measures were OS (time from salvage laryngectomy to death from any cause), disease (...) Nomograms to Precisely Predict Conditional Risk of Survival for Patients With Laryngeal Cancer Nomograms to Precisely Predict Conditional Risk of Survival for Patients With Laryngeal Cancer - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one

2018 Clinical Trials

172. Laryngeal reconstruction in children with recurrent respiratory papillomatosis. (Abstract)

Laryngeal reconstruction in children with recurrent respiratory papillomatosis. To describe our experience in reconstructive laryngeal surgery in patients with recurrent respiratory papillomatosis (RRP).RRP is a rare laryngeal disease requiring multiple surgical endoscopic interventions during its course. These interventions may cause secondary lesions that may compromise airway patency. Open larynx reconstructive surgery, as tracheostomy, is a procedure considered to potentially favor (...) extralaryngeal papilloma dissemination. In patients with RRP, the use of endoscopic posterior cricoid split and rib grafting has not been previously described.The clinical charts of 230 patients with RRP seen between 1996 and 2017 were reviewed. All patients who underwent airway expansion procedures either by open or endoscopic approach were included in the study.Four patients with RRP underwent laryngeal surgery for laryngeal stenosis were included. A double-stage open approach was used in two patients

2018 International Journal of Pediatric Otorhinolaryngology

173. Human papillomavirus infection in patients with laryngeal carcinoma. Full Text available with Trip Pro

. As none of the study samples were HPV positive, it was not possible to compare survival, recurrence, or chemotherapy sensitivity.HPV infection is not a leading cause of laryngeal cancer; however, additional research on HPV positivity in patients with laryngeal cancer and its effect on recurrence, survival, and chemotherapy sensitivity is warranted. (...) Human papillomavirus infection in patients with laryngeal carcinoma. The aim of this study was to determine the HPV positivity rate in patients with laryngeal cancer, and to determine the effect of HPV positivity on survival. An additional aim was to determine if patients with HPV positive laryngeal cancer are more sensitive to chemotherapy and if such sensitivity differs according to chemotherapy protocol.The study included laryngeal specimens obtained from 82 laryngeal cancer patients and 11

2018 BMC Cancer

174. Effect of Magnesium Sulphate Infusion on Lung Mechanics and Oxygenation in COPD Patients Undergoing Total Laryngeal

Effect of Magnesium Sulphate Infusion on Lung Mechanics and Oxygenation in COPD Patients Undergoing Total Laryngeal Effect of Magnesium Sulphate Infusion on Lung Mechanics and Oxygenation in COPD Patients Undergoing Total Laryngeal - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number (...) of saved studies (100). Please remove one or more studies before adding more. Effect of Magnesium Sulphate Infusion on Lung Mechanics and Oxygenation in COPD Patients Undergoing Total Laryngeal (COPD) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT03461328 Recruitment Status : Completed First Posted

2018 Clinical Trials

175. Laryngeal Mask in Upper Gastrointestinal Procedures

Laryngeal Mask in Upper Gastrointestinal Procedures Laryngeal Mask in Upper Gastrointestinal Procedures - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Laryngeal Mask in Upper Gastrointestinal Procedures (...) sedation. Many pharmacologic regimens are available and described in literature. The investigator's institute adopts propofol target controlled infusion (TCI), which usually guarantees unconsciousness and unresponsiveness of patients. The main adverse event is dose-related respiratory depression. Pre-existing reasons for hypoventilation can exacerbate this event, especially in the elderly and the chronic obstructive pulmonary disease-patients. Laryngeal mask (LMA) is a useful tool to apply a pressure

2018 Clinical Trials

176. Nomograms to Precisely Predict Conditional Risk of Recurrence for Patients With Laryngeal Cancer

laryngeal SCC after definitive RT/CRT who has undergone total laryngectomy in order to identify potential preoperative predictors of clinical outcomes. Condition or disease Intervention/treatment Recurrent Laryngeal Cancer Other: Recurrence laryngeal cancer Detailed Description: Demographic, clinical, and survival data were abstracted. Death was verified via medical records and the social security death index. Primary outcome measures were OS (time from salvage laryngectomy to death from any cause (...) : Recurrence laryngeal cancer Recurrence laryngeal cancer has a wide range of invasion, rapid progression and poor prognosis. Outcome Measures Go to Primary Outcome Measures : Overall survival [ Time Frame: Follow up 5 years ] time from salvage laryngectomy to death from any cause Eligibility Criteria Go to Information from the National Library of Medicine Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study

2018 Clinical Trials

177. Analysis of the Curative Effect of Salvage Surgery on Recurrent Laryngeal Carcinoma

pain, ulcers, breathing and eating difficulties caused by recurrent laryngeal cancer seriously reduce the quality of life of patients and seriously endanger their lives. Therefore, head and neck surgeons are required to make every effort to give them saving treatment in order to improve their quality of life. Prolong the patient's life. Condition or disease Intervention/treatment Recurrent Laryngeal Carcinoma Procedure: salvage surgery Detailed Description: medical records and extracted information (...) Analysis of the Curative Effect of Salvage Surgery on Recurrent Laryngeal Carcinoma Analysis of the Curative Effect of Salvage Surgery on Recurrent Laryngeal Carcinoma - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before

2018 Clinical Trials

178. C-fos upregulates P-glycoprotein, contributing to the development of multidrug resistance in HEp-2 laryngeal cancer cells with VCR-induced resistance Full Text available with Trip Pro

C-fos upregulates P-glycoprotein, contributing to the development of multidrug resistance in HEp-2 laryngeal cancer cells with VCR-induced resistance Laryngeal cancer tends to have a very poor prognosis due to the unsatisfactory efficacy of chemotherapy for this cancer. Multidrug resistance (MDR) is the main cause of chemotherapy failure. The proto-oncogene c-fos has been shown to be involved in the development of MDR in several tumor types, but few studies have evaluated the relationship (...) between c-fos and MDR in laryngeal cancer. We investigated the role of c-fos in MDR development in laryngeal cancer cells (cell line: human epithelial type 2, HEp-2) using the chemotherapeutic vincristine (VCR).HEp-2/VCR drug resistance was established by selection against an increasing drug concentration gradient. The expressions of c-fos and multidrug resistance 1 (mdr1) were measured using qPCR and western blot. C-fos overexpression or knockdown was performed in various cells. The intracellular

2018 Cellular & molecular biology letters

179. Transcutaneous Electrical Nerve Stimulation (TENS) and Laryngeal Manual Therapy (LMT): Immediate Effects in Women With Dysphonia. (Abstract)

reported after TENS, and positive laryngeal signs and articulation were reported after LMT.TENS and LMT may be used in voice treatment of women with behavioral dysphonia, and both may be considered important therapy resources that reduce musculoskeletal pain and cause positive laryngeal signs. Both TENS and LMT are able to partially improve voice quality, but TENS presented better results.Copyright © 2018 The Voice Foundation. Published by Elsevier Inc. All rights reserved. (...) Transcutaneous Electrical Nerve Stimulation (TENS) and Laryngeal Manual Therapy (LMT): Immediate Effects in Women With Dysphonia. This study aimed to verify the immediate effect of low-frequency transcutaneous electrical nerve stimulation (TENS) and laryngeal manual therapy (LMT) in musculoskeletal pain, voice quality, and self-reported signs in women with dysphonia.Thirty women with behavioral dysphonia were randomly divided into the TENS group and the LMT group. All participants fulfilled

2018 Journal of voice : official journal of the Voice Foundation Controlled trial quality: uncertain

180. Laryngeal reconstruction for recurrent desmoid tumor using three-dimensional modeling: A unique approach for a rare tumor. (Abstract)

Laryngeal reconstruction for recurrent desmoid tumor using three-dimensional modeling: A unique approach for a rare tumor. Desmoid tumors are exceedingly rare within the larynx and cause significant morbidity due to their locally aggressive and infiltrative nature. Surgery is the mainstay of treatment with previous reports describing total and near-total laryngectomy for cure. We present a case of recurrent glottic desmoid tumor managed with hemilaryngectomy and reconstructed (...) with temporoparietal free tissue, rib, and buccal grafts. Three-dimensional modeling was utilized to optimize aerodigestive function after laryngeal reconstruction. Laryngoscope, 2018.© 2018 The American Laryngological, Rhinological and Otological Society, Inc.

2018 Laryngoscope

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