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Pharyngitis Causes

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81. An unusual cause of inspiratory stridor in the newborn: congenital pharyngeal teratoma - a case report. Full Text available with Trip Pro

An unusual cause of inspiratory stridor in the newborn: congenital pharyngeal teratoma - a case report. Neonatal inspiratory stridor is an important examination finding that requires immediate and adequate evaluation of the underlying etiology. Depending on the severity of the airway obstruction and the presence or absence of associated symptoms such as respiratory distress and feeding problems, early initiation of a complete diagnostic workup can be crucial. The most common cause of neonatal (...) inspiratory stridor is laryngomalacia, however, several differential diagnoses need to be investigated. More rare causes include oral or laryngeal masses. Teratomas of the head and neck region are one of the most unusual causes of respiratory distress during the neonatal period. We present a case of a mature teratoma in the oropharynx presenting with airway obstruction in a newborn infant.A four-day-old female Caucasian infant was admitted to the neonatal intensive care unit of our hospital because

2016 BMC Pediatrics

82. Can trichomoniasis cause pharyngitis? A case report Full Text available with Trip Pro

Can trichomoniasis cause pharyngitis? A case report We report on a heterosexual male with sore throat diagnosed as oral Trichomoniasis vaginalis.A rapid strep test and throat culture were negative. An oropharyngeal swab tested positive for Trichomonas vaginalis using a nucleic acid amplification test (NAAT).A detailed sexual history and oropharyngeal swab testing enabled the diagnosis of oral Trichomoniasis vaginalis in a male patient reporting oral sex with a recently infected female

2016 SAGE Open Medical Case Reports

83. Pharyngeal flap damage caused by nasotracheal intubation in a patient who underwent palatoplasty and pharyngoplasty Full Text available with Trip Pro

Pharyngeal flap damage caused by nasotracheal intubation in a patient who underwent palatoplasty and pharyngoplasty Patients with cleft lip and palate (CLP) must undergo corrective surgeries during infancy and early childhood. Many patients with CLP undergo orthognathic surgery during their childhood for correction of skeletal asymmetries or pharyngoplasty with a pharyngeal flap to improve the quality of speech and velopharyngeal function. During orthognathic surgeries, nasotracheal intubation (...) is performed under general anesthesia. In our case report, the patient had undergone palatoplasty and pharygoplasty previously. During the orthognathic surgery, a flexible fiberoptic bronchoscope-guided nasotracheal tube was inserted through the pharyngeal flap ostium; however, active bleeding occurred in the nasopharynx. Bleeding occurred because the flap was torn. After achieving hemostasis, the surgery was completed successfully. Thus, if a patient may show the potential for velopharyngeal port

2016 Journal of Dental Anesthesia and Pain Medicine

84. Laryngeal Cancer Treatment (PDQ®): Health Professional Version

present with sore throat, painful swallowing, referred ear pain, change in voice quality, or enlarged neck nodes. Early vocal cord cancers are usually detected because of hoarseness. By the time they are detected, cancers arising in the subglottic area commonly involve the vocal cords; thus, symptoms usually relate to contiguous spread. Prognostic Factors The most important adverse prognostic factors for laryngeal cancers include increasing T stage and N (regional lymph node) stage. Other prognostic (...) endolaryngeal surgery (with or without laser) has not been made for patients with early-stage laryngeal cancer. The evidence is insufficient to show a clear difference in the results between treatment options regarding local control or OS. Retrospective data suggest that in comparison with surgery, radiation therapy might cause less perturbation of voice quality without a significant difference in patient perception.[ ] Concurrent Chemoradiation Therapy Concurrent chemoradiation therapy is a standard

2018 PDQ - NCI's Comprehensive Cancer Database

85. Childhood Laryngeal Tumors Treatment (PDQ®): Patient Version

be caused by laryngeal cancer, papillomatosis, or by other . Check with your child's doctor if your child has any of the following: Hoarseness or a change in the voice. Trouble or pain when swallowing. Trouble breathing. A lump in the neck or throat. A sore throat. A cough that does not go away. Earache. Tests that examine the throat are used to diagnose laryngeal cancer. The following tests and procedures may be used: and health history : An exam of the body to check general signs of health, including (...) . There are three main parts of the larynx: : The upper part of the larynx above the vocal cords, including the . : The middle part of the larynx where the vocal cords are located. : The lower part of the larynx between the vocal cords and the trachea. Laryngeal cancer forms in the tissues of the larynx (area of the throat that contains the vocal cords). The larynx includes the supraglottis, glottis (vocal cords), and subglottis. The cancer may spread to nearby tissues or to the thyroid, trachea, or esophagus

2018 PDQ - NCI's Comprehensive Cancer Database

86. Childhood Laryngeal Tumors Treatment (PDQ®): Health Professional Version

.[ ] These tumors can cause hoarseness because of their association with wart-like nodules on the vocal cords, and they may rarely extend into the lung, producing significant morbidity.[ ] Malignant degeneration may occur, with development of cancer in the larynx and squamous cell lung cancer. Treatment of Childhood Laryngeal Papillomatosis Papillomatosis is not cancerous, and primary treatment is surgical ablation with laser vaporization.[ ] Frequent recurrences are common. Lung involvement, although rare, can (...) Childhood Laryngeal Tumors Treatment (PDQ®): Health Professional Version Childhood Laryngeal Tumors Treatment (PDQ®) - PDQ Cancer Information Summaries - NCBI Bookshelf Warning: The NCBI web site requires JavaScript to function. Search database Search term Search NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health. PDQ Cancer Information Summaries [Internet]. Bethesda (MD): National Cancer Institute (US); 2002-. PDQ Cancer Information Summaries [Internet

2018 PDQ - NCI's Comprehensive Cancer Database

87. Laryngeal Cancer Treatment (PDQ®): Patient Version

and ear pain. These and other and may be caused by laryngeal cancer or by other . Check with your doctor if you have any of the following: A sore throat or cough that does not go away. Trouble or pain when swallowing. Ear pain. A lump in the neck or throat. A change or hoarseness in the voice. Tests that examine the throat and neck are used to help diagnose and stage laryngeal cancer. The following tests and procedures may be used: of the throat and neck : An exam to check the throat and neck (...) (not shown). Most form in , the thin, flat lining the inside of the larynx. Laryngeal cancer is a type of . Use of tobacco products and drinking too much alcohol can affect the risk of laryngeal cancer. Anything that increases your risk of getting a disease is called a . Having a risk factor does not mean that you will get ; not having risk factors doesn't mean that you will not get cancer. Talk with your doctor if you think you may be at risk. Signs and symptoms of laryngeal cancer include a sore throat

2018 PDQ - NCI's Comprehensive Cancer Database

88. Letermovir (Prevymis) - to prevent illness caused by cytomegalovirus (CMV) in adults having an allogeneic haematopoietic stem cell transplant

Letermovir (Prevymis) - to prevent illness caused by cytomegalovirus (CMV) in adults having an allogeneic haematopoietic stem cell transplant 30 Churchill Place ? Canary Wharf ? London E14 5EU ? United Kingdom An agency of the European Union Telephone +44 (0)20 3660 6000 Facsimile +44 (0)20 3660 5520 Send a question via our website www.ema.europa.eu/contact © European Medicines Agency, 2018. Reproduction is authorised provided the source is acknowledged. 9 November 2017 EMA/CHMP/490007/2017 (...) population being CMV-seropositive in most countries. Similar to other herpesviruses, acute infection is generally followed by latent (dormant) infection. Among individuals with intact immune systems, reactivation of CMV infection is uncommon and is generally asymptomatic. However, CMV reactivation in immunocompromised patients, such as transplant recipients, can cause significant morbidity and mortality. Annually, approximately 27,000 allogeneic HSCTs are performed worldwide (Gratwohl 2015): in 2014

2018 European Medicines Agency - EPARs

89. Introducing a Virtual Lesion Model of Dysphagia Resulting from Pharyngeal Sensory Impairment. Full Text available with Trip Pro

Introducing a Virtual Lesion Model of Dysphagia Resulting from Pharyngeal Sensory Impairment. Performing neurophysiological and functional imaging studies in severely affected patients to investigate novel neurostimulation techniques for the treatment of neurogenic dysphagia is difficult. Therefore, basic research needs to be conducted in healthy subjects. Swallowing is a motor function highly dependent on sensory afferent input. Here we propose a virtual peripheral sensory lesion model (...) to mimic pharyngeal sensory impairment, which is known as a major contributor to dysphagia in neurological disease.In this randomized crossover study on 11 healthy volunteers, cortical activation during pneumatic pharyngeal stimulation was measured applying magnetoencephalography in two separate sessions, with and without pharyngeal surface anesthesia.Stimulation evoked bilateral event-related desynchronization (ERD) mainly in the caudolateral pericentral cortex. In comparison to the no-anesthesia

2018 Neuro-Signals Controlled trial quality: uncertain

90. Confluent Retropharyngeal, Lateral Pharyngeal, and Peritonsilar MRSA Abscess in an Infant. (Abstract)

Confluent Retropharyngeal, Lateral Pharyngeal, and Peritonsilar MRSA Abscess in an Infant. Neck abscesses such as retropharyngeal, peritonsilar, and lateral pharyngeal are well described, typically cause a characteristic illness, and have a known epidemiology. We present a rare occurrence of case of confluent, mixed retropharyngeal, lateral pharyngeal, and peritonsilar abscess in a 9-month-old female infant. The symptoms at presentation were very mild and not expected in association (...) with this extensive an abscess. The causative organism was methicillin-resistant Staphylococcus aureus.

2018 Pediatric Emergency Care

91. Molecular analysis of Streptococcus pyogenes strains isolated from patients with recurrent pharyngitis after oral amoxicillin treatment. Full Text available with Trip Pro

Molecular analysis of Streptococcus pyogenes strains isolated from patients with recurrent pharyngitis after oral amoxicillin treatment. The most common illness caused by Streptococcus pyogenes (Group A streptococcus; GAS) is acute pharyngitis. It has been reported that a small percentage of patients experience recurrent GAS pharyngitis after 10 days of treatment with oral amoxicillin. The aim of this study was to clarify whether recurrent GAS pharyngitis is reactivation caused by the primary (...) strain remaining at the infection site, or if the reinfection is caused by newly acquired strains.A total of 135 GAS clinical strains were isolated from the tonsils of 116 pediatric patients with acute GAS pharyngitis between November, 2012 and April, 2014 in Saga, Japan. These strains were analysed by pulsed-field gel electrophoresis (PFGE)-typing methods.The isolates were grouped into 16 PFGE-types. The epidemic PFGE types that caused pharyngitis were found to change dynamically during 18 months

2018 Journal of Medical Microbiology

92. Foodborne Outbreak of Group G Streptococcal Pharyngitis in a School Dormitory in Osaka, Japan Full Text available with Trip Pro

Foodborne Outbreak of Group G Streptococcal Pharyngitis in a School Dormitory in Osaka, Japan In September 2016, 140 patients with primary symptoms of sore throat and fever were identified in a school dormitory in Osaka, Japan. Epidemiological and laboratory investigations determined that these symptomatic conditions were from a foodborne outbreak of group G streptococcus (GGS), with GGS being isolated from samples from patients, cooks, and foods. The strain of GGS was identified (...) as Streptococcus dysgalactiae subsp. equisimilis of two emm types (stG652.0 and stC36.0). The causative food, a broccoli salad, was contaminated with the two types of S. dysgalactiae subsp. equisimilis, totaling 1.3 × 104 CFU/g. Pulsed-field gel electrophoresis (PFGE) of samples from patients, cooks, and foods produced similar band patterns among samples with the same emm type. This result suggested the possibility of exposure from the contaminated food. The average onset time was 44.9 h and the prevalence

2018 Journal of clinical microbiology

93. Phenotyping Pharyngeal Pathophysiology Using Polysomnography in Patients with Obstructive Sleep Apnea. Full Text available with Trip Pro

Phenotyping Pharyngeal Pathophysiology Using Polysomnography in Patients with Obstructive Sleep Apnea. Therapies for obstructive sleep apnea (OSA) could be administered on the basis of a patient's own phenotypic causes ("traits") if a clinically applicable approach were available.Here we aimed to provide a means to quantify two key contributors to OSA-pharyngeal collapsibility and compensatory muscle responsiveness-that is applicable to diagnostic polysomnography.Based on physiological (...) definitions, pharyngeal collapsibility determines the ventilation at normal (eupneic) ventilatory drive during sleep, and pharyngeal compensation determines the rise in ventilation accompanying a rising ventilatory drive. Thus, measuring ventilation and ventilatory drive (e.g., during spontaneous cyclic events) should reveal a patient's phenotypic traits without specialized intervention. We demonstrate this concept in patients with OSA (N = 29), using a novel automated noninvasive method to estimate

2018 American Journal of Respiratory and Critical Care Medicine

94. B Part of It protocol: a cluster randomised controlled trial to assess the impact of 4CMenB vaccine on pharyngeal carriage of <i>Neisseria meningitidis</i> in adolescents. Full Text available with Trip Pro

B Part of It protocol: a cluster randomised controlled trial to assess the impact of 4CMenB vaccine on pharyngeal carriage of Neisseria meningitidis in adolescents. South Australia (SA) has the highest notification rate of invasive meningococcal disease in Australia with the majority of cases due to serogroup B. Neisseria meningitidis is carried in the pharynx, with adolescents having the highest rates of carriage. A vaccine designed to offer protection against serogroup B (4CMenB (...) . A questionnaire will be completed at baseline and 12 months to assess risk factors associated with carriage. The primary outcome of carriage prevalence of disease causing N. meningitidis at 12 months will be compared between groups using logistic regression, with generalised estimating equations used to account for clustering at the school level. The difference in carriage prevalence between groups will be expressed as an OR with 95% CI.The study was approved by the Women's and Children's Health Network Human

2018 BMJ open Controlled trial quality: predicted high

95. Axon and Schwann cell degeneration in nerves of upper airway relates to pharyngeal dysfunction in snorers and sleep apnea patients. Full Text available with Trip Pro

frequently observed in patients compared with control subjects (11.3 ± 4.2% vs 4.8 ± 2.4%; P = .02).Axon degeneration in preterminal nerves of the soft palate is associated with pharyngeal dysfunction in snorers and patients with sleep apnea. The most likely cause for the nerve injuries is traumatic snoring vibrations and tissue stretch, leading to swallowing dysfunction and increased risk for upper airway obstruction during sleep.Copyright © 2018 The Authors. Published by Elsevier Inc. All rights (...) Axon and Schwann cell degeneration in nerves of upper airway relates to pharyngeal dysfunction in snorers and sleep apnea patients. The pathophysiologic mechanism of nocturnal obstruction and swallowing dysfunction commonly occurring in patients with sleep apnea is unclear. The goal of this study was to investigate whether nerve injuries in the upper airways of snorers and patients with sleep apnea are associated with pharyngeal dysfunction and severity of sleep apnea.Twenty-two patients

2018 Chest

96. Tonsillar antimicrobial peptide (AMP) expression profiles of periodic fever, aphthous stomatitis, pharyngitis, cervical adenitis (PFAPA) patients. (Abstract)

Tonsillar antimicrobial peptide (AMP) expression profiles of periodic fever, aphthous stomatitis, pharyngitis, cervical adenitis (PFAPA) patients. PFAPA (periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis) is the most frequent non-infectious cause of high fever observed among the European child population. While its cause is still not yet fully identified, PFAPA patients were previously shown to have altered tonsillar microbiome composition. Our study hypothesized

2018 International Journal of Pediatric Otorhinolaryngology

97. Point of Care Streptococcal Pharyngitis Testing

by (Responsible Party): Quynh Doan, University of British Columbia Study Details Study Description Go to Brief Summary: Sore throat is a common problem in children typically caused by viral or bacterial infections. While viral infections resolve without treatment, bacterial infections, such as "strep throat," are treatable with antibiotics. Diagnosing "strep throat" traditionally required a throat swab for culture that delays treatment for several days. This may result in prolonged illness, activity (...) Ages Eligible for Study: 3 Years to 17 Years (Child) Sexes Eligible for Study: All Accepts Healthy Volunteers: No Criteria Inclusion Criteria: Children 3-17 years of age who seek care in a ED with sore throat, and in whom the ED clinician is considering a throat swab for culture for suspected GAS pharyngitis. In addition, only English speaking families will be recruited. Exclusion Criteria: Patients younger than 3 and older than 17 years of age will be excluded. In addition, patients who had

2018 Clinical Trials

98. Cephalic de-mucosalized superiorly-based pharyngeal flap: A modified mucosa-preserving technique for velopharyngeal insufficiency. (Abstract)

Cephalic de-mucosalized superiorly-based pharyngeal flap: A modified mucosa-preserving technique for velopharyngeal insufficiency. Superiorly-based pharyngeal flap (PF) is the most frequently employed surgical technique to correct velopharyngeal insufficiency (VPI). Bared posterior pharyngeal wall might prolong the period of convalescence with throat pain and discomfort. Delayed donor site healing problems and subsequent fibrosis with downward migration of the transposed flap might be one (...) a cause of failure and might necessitate revision.To present a modified technique of PF aiming at dealing with the problems of donor site defects via immediate self-mucosal covering of the cephalic portion of the bed.This case series study was conducted on patients with persistent VPI. All patients underwent the new modified technique of cephalic de-mucosalized pharyngeal flap (CDPF). The basic premise was to harvest a laterally-based mucosal flap from the upper part of the posterior pharyngeal wall

2018 International Journal of Pediatric Otorhinolaryngology

99. Pharyngeal dysphagia due to Varicella zoster virus meningoradiculitis and full recovery: Case report and endoscopic findings Full Text available with Trip Pro

Pharyngeal dysphagia due to Varicella zoster virus meningoradiculitis and full recovery: Case report and endoscopic findings Varicella zoster virus reactivation is a rare cause of pharyngeal dysphagia with long-term sequelae persisting in most cases. A 76-year-old immunocompetent woman presented with a 4-week history of dysphagia and dysphonia. Brain magnetic resonance imaging displayed a negative finding. Fiberoptic endoscopic evaluation of swallowing showed a severe dysphagia leading (...) to a percutaneous gastrostomy eventually. Cerebrospinal fluid analysis revealed a lymphocytic pleocytosis and polymerase chain reaction amplified Varicella zoster virus DNA. Eight months after Acyclovir treatment and despite a persisting impairment of the recurrent laryngeal nerve, regular swallowing function was regained and percutaneous gastrostomy could be removed.

2018 SAGE Open Medical Case Reports

100. Streptococcal Group A, C, and G Pharyngitis in School Children: A Prospective Cohort Study in Southern India Full Text available with Trip Pro

Streptococcal Group A, C, and G Pharyngitis in School Children: A Prospective Cohort Study in Southern India Diagnosing streptococcal pharyngitis in children on the basis of clinical appearance and throat culture is complicated by high colonisation rates and by the ability of other pathogens to cause clinically similar disease. To characterise the epidemiology of Lancefield Group A, C and G β-haemolytic streptococcus (GAS, GCS and GGS, respectively) in children, we conducted a 2-year (...) prospective study of 307 school children between 7 and 11 years old. GGS and GAS were commonly identified organisms both for silent streptococcal colonisation and symptomatic sore throat, while GCS was uncommonly found. Streptococcal culture positivity at the time of clinical pharyngitis was estimated to reflect true streptococcal pharyngitis in only 26% of instances, with the frequency varying from 54% for children rarely colonised to 1% for children frequently colonised. Numerous GAS emm types were

2018 Epidemiology and infection

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