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Pharyngitis Causes

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181. Pharyngeal swallowing phase and chronic cough (PubMed)

Pharyngeal swallowing phase and chronic cough  The act of swallowing depends on a complex and dynamic process which uses common structures to the act of breathing; respiratory problems can cause swallowing difficulties. To assess the swallowing pharyngeal phase in patients with chronic cough. Retrospective study with 15 patients of both genders, patients with chronic cough and risk factors for aspiration defined by the pneumologic diagnosis. The patients were submitted to anamnesis

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2012 International archives of otorhinolaryngology

182. Pharyngeal pouch surgery: A combined open and endoscopic approach. (PubMed)

Pharyngeal pouch surgery: A combined open and endoscopic approach. Pharyngeal pouches are common, particularly in the elderly population, in whom they can cause significant morbidity. The advanced age of many patients and existing comorbidities mean that in some cases neither open nor endoscopic pouch stapling is possible. We present a technique of combined open and endoscopic pharyngeal pouch surgery, which may be used when other therapeutic options are limited.Copyright © 2012 The American

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2012 Laryngoscope

183. Videofluoroscopic assessment of pharyngeal stage delay reflects pathophysiology after brain infarction. (PubMed)

Videofluoroscopic assessment of pharyngeal stage delay reflects pathophysiology after brain infarction. The pathophysiology of dysphagia caused by brain infarction varies with the site of the lesion in the brain. Patients with suprabulbar lesions have demonstrated delayed triggering of pharyngeal stage including delayed laryngeal elevation. Patients with severe pharyngeal stage delay have a high risk of intractable aspiration to the lower respiratory tract. Despite this, few studies have (...) compared the pharyngeal stage delay with the lesion site. We defined a new temporal parameter of the pharyngeal stage delay to assess laryngeal elevation delay against the bolus inflow into the pharyngeal space. This study aimed to elucidate whether this parameter of pharyngeal stage delay is clinically useful to assess the pathophysiology of brain lesions after brain infarction.Case-control study.Videofluoroscopic assessment of swallowing examinations was performed from January 7, 2000 to March 29

2012 Laryngoscope

184. Periodic fevers with aphthous stomatitis, pharyngitis, and adenitis (PFAPA). (PubMed)

Periodic fevers with aphthous stomatitis, pharyngitis, and adenitis (PFAPA). PFAPA syndrome (acronym of periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis) is the most common cause of periodic fever in childhood. Nowadays, it is considered part of the wide family of the autoinflammatory diseases, but a genetic or molecular marker hasn't been identified yet, therefore, its etiology is still unknown. Diagnosis is essentially based on clinical criteria but, especially

2012 Autoimmunity reviews

185. Cost-effectiveness of pharmacist-provided treatment of adult pharyngitis. (PubMed)

-effectiveness of a community pharmacist-as-provider program for the diagnosis and treatment of pharyngitis caused by GAS as compared with standard of care.A cost-effectiveness analysis was conducted to compare treatment for adult pharyngitis patients. In addition to 5 physician-provided treatment strategies, the episodic costs and benefits of treatment provided by pharmacists using RADT and walk-in clinics using RADT were also considered. Model parameters were derived through a comprehensive review (...) -effectiveness ratio (ICER) for physician culture was $6042 per QALD gained and $40,745 for physician RADT with follow-up culture.This model suggests that pharmacists may be able to provide a cost-effective alternative for the treatment of pharyngitis caused by GAS in adult patients.

2012 American Journal Of Managed Care

186. Obesity and obstructive sleep apnoea: mechanisms for increased collapsibility of the passive pharyngeal airway. (PubMed)

the airway. Even mild obesity may cause anatomical imbalance in individuals with a small maxilla and mandible. Lung volume reduction due to excessive central fat deposition may decrease longitudinal tracheal traction forces and pharyngeal wall tension, changing the 'tube law' in the pharyngeal airway (lung volume dependence of the upper airway). The lung volume dependence of pharyngeal airway patency appears to contribute more significantly to the development of OSA in morbidly obese, apnoeic patients (...) Obesity and obstructive sleep apnoea: mechanisms for increased collapsibility of the passive pharyngeal airway. Epidemiological evidence suggests there are significant links between obesity and obstructive sleep apnoea (OSA), with a particular emphasis on the importance of fat distribution in the development of OSA. In patients with OSA, the structure of the pharyngeal airway collapses. A collapsible tube within a rigid box collapses either due to decreased intraluminal pressure or increased

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2012 Respirology

187. Mechanisms of Pharyngeal Collapse in Sleep Apnea, Study B

expiration (Progressive Expiratory Narrowing, PEN) preceding an obstructive apnea. The cause of PEN is unknown. The investigators will test if lung volumes and low respiratory drive play a role in PEN. Condition or disease Intervention/treatment Phase Sleep Apnea Other: Induction of flow limitation Not Applicable Detailed Description: The mechanisms that lead to airway closure in OSA are not completely understood. Some studies have shown that there is progressive narrowing of the pharyngeal airway across (...) Mechanisms of Pharyngeal Collapse in Sleep Apnea, Study B Mechanisms of Pharyngeal Collapse in Sleep Apnea, Study B - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Mechanisms of Pharyngeal Collapse in Sleep

2012 Clinical Trials

188. The velo-uvulo-pharyngeal lift or "roman blinds" technique for treatment of snoring: a preliminary report (PubMed)

The velo-uvulo-pharyngeal lift or "roman blinds" technique for treatment of snoring: a preliminary report Snoring is caused by vibrating anatomical structures in the upper aerodigestive tract. It can be treated surgically and non-surgically, although resective procedures are associated with high postoperative morbidity and failure rate. We describe a new non-resective surgical procedure called the velo-uvulo-pharyngeal lift in which the soft palate is lifted, shortened, advanced and stiffened (...) by means of permanent threads anchored to fibro-osseous attachments at the level of the posterior nasal spine and both pterygoid hamuli. Four adult patients (median age 44.5 years; range 42-65) affected by snoring and mild obstructive sleep apnoea-hypopnoea syndrome (apneoa-hypopnoea index, AHI < 20) requiring septal surgery under general anesthesia also underwent velo-uvulo-pharyngeal lift. There were no significant intra- or post-operative complications, and all of the patients reported immediate

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2012 Acta Otorhinolaryngologica Italica

189. Effectiveness of the analysis of craniofacial morphology and pharyngeal airway morphology in the treatment of children with obstructive sleep apnoea syndrome (PubMed)

with the non-op group, and it was speculated that there was a high probability of the necessity of surgical therapy (adenotonsillectomy) when a morphological factor played a major role as a cause of obstructive sleep apnoea. We recommend craniofacial morphology analysis and pharyngeal airway morphology analysis in the diagnosis and treatment planning of OSAS children. (...) Effectiveness of the analysis of craniofacial morphology and pharyngeal airway morphology in the treatment of children with obstructive sleep apnoea syndrome In general, no consensus has been reached regarding the diagnostic criteria for obstructive sleep apnoea syndrome (OSAS) in children and the criteria for selecting treatment are inconsistent. Therefore, the craniofacial and pharyngeal airway morphology of OSAS in children who had undergone drug therapy (non-op group) and OSAS in children

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2012 Dentomaxillofacial Radiology

190. Chronic Pharyngeal Carriage of Streptococcus pyogenes

Cancer Administration 4 Chronic Pharyngeal Carriage of Streptococcus pyogenes Chronic Pharyngeal Carriage of Streptococcus pyogenes Aka: Chronic Pharyngeal Carriage of Streptococcus pyogenes , Group A Streptococcus Pharyngeal Carrier , GAS Pharyngeal Carrier From Related Chapters II. Signs Recurrent episodes GAS diagnosed with every new cold presumed due to non-GAS cause III. Diagnosis (Test when patient is well and asymptomatic) Streptococcal titer (ASO) Obtain baseline value Repeat in 4-6 weeks IV (...) Chronic Pharyngeal Carriage of Streptococcus pyogenes Chronic Pharyngeal Carriage of Streptococcus pyogenes Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse

2015 FP Notebook

191. Group A Streptococcal Pharyngitis

Endocarditis V. Symptoms Stretococcal exposure in last 2 weeks ( 19%, 91%) ( >100.9) absent Myalgia VI. Signs See Palatal ( 7%, 95%) Pharyngeal exudate ( 26%, 88%) VII. Differential Diagnosis See Common other causes Posterior cervical adenopathy, and prolonged Hand, foot and mouth disease s, hand and foot skin lesions VIII. Labs Used to distinguish intermediate probability of Streptococcal Pharyngitis (Centor Score 2-3) : 86% : 96% Used to confirm a negative rapid antigen test IDSA recommends confirmatory (...) Group A Streptococcal Pharyngitis Group A Streptococcal Pharyngitis Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Group

2015 FP Notebook

192. Pharyngitis

Related Chapters II. Epidemiology One of four most common episodic clinic visit reasons III. Anatomy: Waldeyer's Tonsillar ring Nasopharynx Adenoids (pharyngeal s) at posterior wall Oropharynx Faucial ( s) at lateral wall) Hypopharynx Lingual at base IV. Causes See V. Symptoms Sore Throat (Difficulty swallowing) Odynophagia (pain with swallowing) ralized symptoms , Chills, Malaise or Symptoms suggestive of viral illness VI. Signs: Red flags (suggestive of serious cause) Unilateral Pharyngitis Toxic (...) and bacterial infections. Other causes include allergens, chemical substances, and trauma. Definition (NCI_CTCAE) A disorder characterized by inflammation of the throat. Definition (CSP) inflammation of the throat. Concepts Disease or Syndrome ( T047 ) MSH SnomedCT 141458004 , 164261009 , 37616004 , 405737000 English Pharyngitides , Inflamed throat , pharynx inflammation , inflammation of pharynx (physical finding) , pharyngeal inflammation , inflammation of pharynx , pharyngitis (diagnosis) , pharyngitis

2015 FP Notebook

193. Mesodermal retinoic acid signaling regulates endothelial cell coalescence in caudal pharyngeal arch artery vasculogenesis (PubMed)

Mesodermal retinoic acid signaling regulates endothelial cell coalescence in caudal pharyngeal arch artery vasculogenesis Disruption of retinoic acid signaling causes a variety of pharyngeal arch artery and great vessel defects, as well as malformations in many other tissues, including those derived from the pharyngeal endoderm. Previous studies implied that arch artery defects in the context of defective RA signaling occur secondary to pharyngeal pouch segmentation defects, although this model (...) has never been experimentally verified. In this study, we examined arch artery morphogenesis during mouse development, and the role of RA in this process. We show in normal embryos that the arch arteries form by vasculogenic differentiation of pharyngeal mesoderm. Using various genetic backgrounds and tissue-specific mutation approaches, we segregate pharyngeal arch artery and pharyngeal pouch defects in RA receptor mutants, and show that RA signal transduction only in pharyngeal mesoderm

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2011 Developmental biology

194. Direct association between pharyngeal viral secretion and host cytokine response in severe pandemic influenza. (PubMed)

Direct association between pharyngeal viral secretion and host cytokine response in severe pandemic influenza. Severe disease caused by 2009 pandemic influenza A/H1N1virus is characterized by the presence of hypercytokinemia. The origin of the exacerbated cytokine response is unclear. As observed previously, uncontrolled influenza virus replication could strongly influence cytokine production. The objective of the present study was to evaluate the relationship between host cytokine responses (...) and viral levels in pandemic influenza critically ill patients.Twenty three patients admitted to the ICU with primary viral pneumonia were included in this study. A quantitative PCR based method targeting the M1 influenza gene was developed to quantify pharyngeal viral load. In addition, by using a multiplex based assay, we systematically evaluated host cytokine responses to the viral infection at admission to the ICU. Correlation studies between cytokine levels and viral load were done by calculating

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2011 BMC Infectious Diseases

195. Group A Streptococcus emm Gene Types in Pharyngeal Isolates, Ontario, Canada, 2002-2010. (PubMed)

Group A Streptococcus emm Gene Types in Pharyngeal Isolates, Ontario, Canada, 2002-2010. Group A Streptococcus (GAS) is a human-adapted pathogen that causes a variety of diseases, including pharyngitis and invasive infections. GAS strains are categorized by variation in the nucleotide sequence of the gene (emm) that encodes the M protein. To identify the emm types of GAS strains causing pharyngitis in Ontario, Canada, we sequenced the hypervariable region of the emm gene in 4,635 pharyngeal GAS (...) isolates collected during 2002-2010. The most prevalent emm types varied little from year to year. In contrast, fine-scale geographic analysis identified inter-site variability in the most common emm types. Additionally, we observed fluctuations in yearly frequency of emm3 strains from pharyngitis patients that coincided with peaks of emm3 invasive infections. We also discovered a striking increase in frequency of emm89 strains among isolates from patients with pharyngitis and invasive disease

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2011 Emerging Infectious Diseases

196. Topical Pharyngeal Anesthesia With Articaine for Gastroscopy

Topical Pharyngeal Anesthesia With Articaine for Gastroscopy Topical Pharyngeal Anesthesia With Articaine for Gastroscopy - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Topical Pharyngeal Anesthesia (...) Central Hospital Study Details Study Description Go to Brief Summary: Topical Pharyngeal anesthesia (TPA) is widely used during upper endoscopy. Articaine is local anaesthetic that have not been previously evaluated in pharyngeal anesthesia for upper endoscopy. The aim of this study was to compare pharyngeal anesthesia with 4% articaine to placebo (Na0,9%) during gastroscopy in terms of benefit on patients` and endoscopists` satisfaction. Condition or disease Intervention/treatment Phase Gastroscopy

2011 Clinical Trials

197. Predicting streptococcal pharyngitis in adults in primary care: a systematic review of the diagnostic accuracy of symptoms and signs and validation of the Centor score. (PubMed)

Predicting streptococcal pharyngitis in adults in primary care: a systematic review of the diagnostic accuracy of symptoms and signs and validation of the Centor score. Stratifying patients with a sore throat into the probability of having an underlying bacterial or viral cause may be helpful in targeting antibiotic treatment. We sought to assess the diagnostic accuracy of signs and symptoms and validate a clinical prediction rule (CPR), the Centor score, for predicting group A β-haemolytic (...) streptococcal (GABHS) pharyngitis in adults (> 14 years of age) presenting with sore throat symptoms.A systematic literature search was performed up to July 2010. Studies that assessed the diagnostic accuracy of signs and symptoms and/or validated the Centor score were included. For the analysis of the diagnostic accuracy of signs and symptoms and the Centor score, studies were combined using a bivariate random effects model, while for the calibration analysis of the Centor score, a random effects model

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2011 BMC Medicine

198. Group A Streptococcus Gene Expression in Humans with Pharyngitis using a Microarray. (PubMed)

Group A Streptococcus Gene Expression in Humans with Pharyngitis using a Microarray. Pharyngitis caused by group A streptococci (GAS) is one of the most common infections around the world. However, relatively little is known about which genes are expressed and which genes regulate expression during acute infection. Due to their ability to provide genome-wide views of gene expression at one time, microarrays are increasingly being incorporated in GAS research. In this study, a novel (...) electrochemical detection-based microarray was used to identify gene expression patterns among humans with culture-confirmed GAS pharyngitis. Using 14 samples (11 GAS-positive and three GAS-negative) obtained from subjects seen at the Brooke Army Medical Center paediatric clinic, this study demonstrated two different clusters of gene expression patterns. One cluster expressed a larger number of genes related to phages, immune-system evasion and survival among competing oral flora, signifying a potentially

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2011 Journal of Medical Microbiology

199. Absence of wide-zone, alpha-hemolytic streptococci in children with pharyngitis. (PubMed)

magnification. One-third of all cultures were positive for beta-hemolytic streptococci. There were no significant differences in the number of positive cultures among or between the different methods. Wide-zone, alpha-streptococci were found in none of the cultures. Therefore, they are unlikely to be a common cause of false-positive cultures in children with pharyngitis. (...) Absence of wide-zone, alpha-hemolytic streptococci in children with pharyngitis. Wide-zone, alpha-hemolytic streptococci are potential sources of false-positive throat cultures since they can be misinterpreted as beta-hemolytic streptococci. However, quantitative information regarding their occurrence in sick children was not available. Throat swabs from 312 children with pharyngitis were processed conventionally and also with pour-plate methods and examination of the positive cultures under

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1976 Journal of clinical microbiology

200. BACTERIOSTATIC EFFECT OF HUMAN SERA ON GROUP A STREPTOCOCCI : I. TYPE-SPECIFIC ANTIBODIES IN SERA OF PATIENTS CONVALESCING FROM GROUP A STREPTOCOCCAL PHARYNGITIS (PubMed)

BACTERIOSTATIC EFFECT OF HUMAN SERA ON GROUP A STREPTOCOCCI : I. TYPE-SPECIFIC ANTIBODIES IN SERA OF PATIENTS CONVALESCING FROM GROUP A STREPTOCOCCAL PHARYNGITIS 1. Type-specific antibodies were demonstrated by the indirect bacteriostatic test in sera from human adults convalescing from group A streptococcal infection of the upper respiratory tract. The time of appearance of the antibodies varied from 3 to 5 weeks; and they persisted in 2 patients for at least 37 weeks after the onset (...) of the infection. 2. The specificity of the antibody response in one serum was tested with strains of 7 heterologous types; in another, with 6; and in the third, with 2; but in no instance were cross-reactions observed. Moreover, each convalescent serum showed approximately equal bacteriostasis for 7 different strains of the same type as that which caused the infection. 3. The antibodies were specifically absorbed from the serum by homologous heat-killed streptococci, but not significantly by strains

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1945 The Journal of experimental medicine

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