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Pharyngitis Causes

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181. Human papillomavirus infection in patients with laryngeal carcinoma. Full Text available with Trip Pro

. As none of the study samples were HPV positive, it was not possible to compare survival, recurrence, or chemotherapy sensitivity.HPV infection is not a leading cause of laryngeal cancer; however, additional research on HPV positivity in patients with laryngeal cancer and its effect on recurrence, survival, and chemotherapy sensitivity is warranted. (...) Human papillomavirus infection in patients with laryngeal carcinoma. The aim of this study was to determine the HPV positivity rate in patients with laryngeal cancer, and to determine the effect of HPV positivity on survival. An additional aim was to determine if patients with HPV positive laryngeal cancer are more sensitive to chemotherapy and if such sensitivity differs according to chemotherapy protocol.The study included laryngeal specimens obtained from 82 laryngeal cancer patients and 11

2018 BMC Cancer

182. Effect of Magnesium Sulphate Infusion on Lung Mechanics and Oxygenation in COPD Patients Undergoing Total Laryngeal

Effect of Magnesium Sulphate Infusion on Lung Mechanics and Oxygenation in COPD Patients Undergoing Total Laryngeal Effect of Magnesium Sulphate Infusion on Lung Mechanics and Oxygenation in COPD Patients Undergoing Total Laryngeal - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number (...) of saved studies (100). Please remove one or more studies before adding more. Effect of Magnesium Sulphate Infusion on Lung Mechanics and Oxygenation in COPD Patients Undergoing Total Laryngeal (COPD) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT03461328 Recruitment Status : Completed First Posted

2018 Clinical Trials

183. Laryngeal Mask in Upper Gastrointestinal Procedures

Laryngeal Mask in Upper Gastrointestinal Procedures Laryngeal Mask in Upper Gastrointestinal Procedures - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Laryngeal Mask in Upper Gastrointestinal Procedures (...) sedation. Many pharmacologic regimens are available and described in literature. The investigator's institute adopts propofol target controlled infusion (TCI), which usually guarantees unconsciousness and unresponsiveness of patients. The main adverse event is dose-related respiratory depression. Pre-existing reasons for hypoventilation can exacerbate this event, especially in the elderly and the chronic obstructive pulmonary disease-patients. Laryngeal mask (LMA) is a useful tool to apply a pressure

2018 Clinical Trials

184. Nomograms to Precisely Predict Conditional Risk of Recurrence for Patients With Laryngeal Cancer

laryngeal SCC after definitive RT/CRT who has undergone total laryngectomy in order to identify potential preoperative predictors of clinical outcomes. Condition or disease Intervention/treatment Recurrent Laryngeal Cancer Other: Recurrence laryngeal cancer Detailed Description: Demographic, clinical, and survival data were abstracted. Death was verified via medical records and the social security death index. Primary outcome measures were OS (time from salvage laryngectomy to death from any cause (...) : Recurrence laryngeal cancer Recurrence laryngeal cancer has a wide range of invasion, rapid progression and poor prognosis. Outcome Measures Go to Primary Outcome Measures : Overall survival [ Time Frame: Follow up 5 years ] time from salvage laryngectomy to death from any cause Eligibility Criteria Go to Information from the National Library of Medicine Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study

2018 Clinical Trials

185. Analysis of the Curative Effect of Salvage Surgery on Recurrent Laryngeal Carcinoma

pain, ulcers, breathing and eating difficulties caused by recurrent laryngeal cancer seriously reduce the quality of life of patients and seriously endanger their lives. Therefore, head and neck surgeons are required to make every effort to give them saving treatment in order to improve their quality of life. Prolong the patient's life. Condition or disease Intervention/treatment Recurrent Laryngeal Carcinoma Procedure: salvage surgery Detailed Description: medical records and extracted information (...) Analysis of the Curative Effect of Salvage Surgery on Recurrent Laryngeal Carcinoma Analysis of the Curative Effect of Salvage Surgery on Recurrent Laryngeal Carcinoma - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before

2018 Clinical Trials

186. C-fos upregulates P-glycoprotein, contributing to the development of multidrug resistance in HEp-2 laryngeal cancer cells with VCR-induced resistance Full Text available with Trip Pro

C-fos upregulates P-glycoprotein, contributing to the development of multidrug resistance in HEp-2 laryngeal cancer cells with VCR-induced resistance Laryngeal cancer tends to have a very poor prognosis due to the unsatisfactory efficacy of chemotherapy for this cancer. Multidrug resistance (MDR) is the main cause of chemotherapy failure. The proto-oncogene c-fos has been shown to be involved in the development of MDR in several tumor types, but few studies have evaluated the relationship (...) between c-fos and MDR in laryngeal cancer. We investigated the role of c-fos in MDR development in laryngeal cancer cells (cell line: human epithelial type 2, HEp-2) using the chemotherapeutic vincristine (VCR).HEp-2/VCR drug resistance was established by selection against an increasing drug concentration gradient. The expressions of c-fos and multidrug resistance 1 (mdr1) were measured using qPCR and western blot. C-fos overexpression or knockdown was performed in various cells. The intracellular

2018 Cellular & molecular biology letters

187. Transcutaneous Electrical Nerve Stimulation (TENS) and Laryngeal Manual Therapy (LMT): Immediate Effects in Women With Dysphonia. (Abstract)

reported after TENS, and positive laryngeal signs and articulation were reported after LMT.TENS and LMT may be used in voice treatment of women with behavioral dysphonia, and both may be considered important therapy resources that reduce musculoskeletal pain and cause positive laryngeal signs. Both TENS and LMT are able to partially improve voice quality, but TENS presented better results.Copyright © 2018 The Voice Foundation. Published by Elsevier Inc. All rights reserved. (...) Transcutaneous Electrical Nerve Stimulation (TENS) and Laryngeal Manual Therapy (LMT): Immediate Effects in Women With Dysphonia. This study aimed to verify the immediate effect of low-frequency transcutaneous electrical nerve stimulation (TENS) and laryngeal manual therapy (LMT) in musculoskeletal pain, voice quality, and self-reported signs in women with dysphonia.Thirty women with behavioral dysphonia were randomly divided into the TENS group and the LMT group. All participants fulfilled

2018 Journal of voice : official journal of the Voice Foundation Controlled trial quality: uncertain

188. Laryngeal reconstruction for recurrent desmoid tumor using three-dimensional modeling: A unique approach for a rare tumor. (Abstract)

Laryngeal reconstruction for recurrent desmoid tumor using three-dimensional modeling: A unique approach for a rare tumor. Desmoid tumors are exceedingly rare within the larynx and cause significant morbidity due to their locally aggressive and infiltrative nature. Surgery is the mainstay of treatment with previous reports describing total and near-total laryngectomy for cure. We present a case of recurrent glottic desmoid tumor managed with hemilaryngectomy and reconstructed (...) with temporoparietal free tissue, rib, and buccal grafts. Three-dimensional modeling was utilized to optimize aerodigestive function after laryngeal reconstruction. Laryngoscope, 2018.© 2018 The American Laryngological, Rhinological and Otological Society, Inc.

2018 Laryngoscope

189. Molecular and immunologic analysis of laryngeal squamous cell carcinoma in smokers and non-smokers. Full Text available with Trip Pro

Molecular and immunologic analysis of laryngeal squamous cell carcinoma in smokers and non-smokers. Laryngeal squamous cell carcinoma (LSCC) is strongly associated with tobacco use, but recent reports suggest an increasing incidence of LSCC in patients without traditional risk factors, suggesting an alternative etiology of tumorigenesis. The purpose of this study is to characterize this non-smoking population and to compare immunohistochemical markers in tumor specimens from non-smokers (...) smokers with LSCC. In TMA analysis of stage and age-matched specimens from smoker and non-smokers with LSCC, the pattern of expression for common molecular and immunologic markers is similar. Further, HPV does not appear to be a major causative etiology of LSCC in either smokers or non-smokers in our cohort of patients.Copyright © 2018 Elsevier Inc. All rights reserved.

2018 American Journal of Otolaryngology

190. A comparison of sampling methods for examining the laryngeal microbiome. Full Text available with Trip Pro

A comparison of sampling methods for examining the laryngeal microbiome. Shifts in healthy human microbial communities have now been linked to disease in numerous body sites. Noninvasive swabbing remains the sampling technique of choice in most locations; however, it is not well known if this method samples the entire community, or only those members that are easily removed from the surface. We sought to compare the communities found via swabbing and biopsied tissue in true vocal folds (...) , a location that is difficult to sample without causing potential damage and impairment to tissue function. A secondary aim of this study was to determine if swab sampling of the false vocal folds could be used as proxy for true vocal folds. True and false vocal fold mucosal samples (swabbed and biopsied) were collected from six pigs and used for 454 pyrosequencing of the V3-V5 region of the 16S rRNA gene. Most of the alpha and beta measures of diversity were found to be significantly similar between

2017 PLoS ONE

191. Laryngeal evidence for the first and second passaggio in professionally trained sopranos. Full Text available with Trip Pro

through the respective passaggi.Noteworthy vocal fold oscillatory registration events occur in both the first and the second passaggio even in professional sopranos. The respective transitions are hypothesized to be caused by either (a) a change of laryngeal biomechanical properties; or by (b) vocal tract resonance effects, constituting level 2 source-filter interactions. (...) Laryngeal evidence for the first and second passaggio in professionally trained sopranos. Due to a lack of empirical data, the current understanding of the laryngeal mechanics in the passaggio regions (i.e., the fundamental frequency ranges where vocal registration events usually occur) of the female singing voice is still limited.In this study the first and second passaggio regions of 10 professionally trained female classical soprano singers were analyzed. The sopranos performed pitch glides

2017 PLoS ONE

192. How to teach clinical medicine – lessons learned by studying sore throats for 35 years

How to teach clinical medicine – lessons learned by studying sore throats for 35 years db's Medical Rants » Blog Archive » How to teach clinical medicine – lessons learned by studying sore throats for 35 years Internal medicine, American health care, and especially medical education 4 Posted by rcentor | Posted on 04-06-2015 Category : , 35 years ago I started collecting data in a non-acute emergency room. Over approximately 3 months the residents enrolled slightly more than 300 patients (...) into the initial sore throat study. Spending the next 3 months learning how to analyze the data, I began a long journey that continues today. Learning medicine rarely includes having epiphanies. Learning medicine requires patients and reading. But we who teach medicine can help our learners speed that process if we help them focus on some key features. My colleagues and I often cite Judy Bowen’s classic article – Bowen, Judith L. “Educational strategies to promote clinical diagnostic reasoning.” New England

2015 db's Medical Rants blog

193. Chronic Pharyngeal Carriage of Streptococcus pyogenes

Cancer Administration 4 Chronic Pharyngeal Carriage of Streptococcus pyogenes Chronic Pharyngeal Carriage of Streptococcus pyogenes Aka: Chronic Pharyngeal Carriage of Streptococcus pyogenes , Group A Streptococcus Pharyngeal Carrier , GAS Pharyngeal Carrier From Related Chapters II. Signs Recurrent episodes GAS diagnosed with every new cold presumed due to non-GAS cause III. Diagnosis (Test when patient is well and asymptomatic) Streptococcal titer (ASO) Obtain baseline value Repeat in 4-6 weeks IV (...) bid for 4 days and Benzathine VI. References (2000) AAP Red Book, p. 532 Mandell (2000) Principles Infectious Disease, p. 353 Images: Related links to external sites (from Bing) These images are a random sampling from a Bing search on the term "Chronic Pharyngeal Carriage of Streptococcus pyogenes." Click on the image (or right click) to open the source website in a new browser window. Related Studies (from Trip Database) Related Topics in Throat Disease About FPnotebook.com is a rapid access

2018 FP Notebook

194. Group A Streptococcal Pharyngitis

are a random sampling from a Bing search on the term "Group A Streptococcal Pharyngitis." Click on the image (or right click) to open the source website in a new browser window. Related Studies (from Trip Database) Ontology: Streptococcal sore throat (C0036689) Concepts Disease or Syndrome ( T047 ) ICD9 034.0 ICD10 SnomedCT 154302004 , 186358002 , 186360000 , 186361001 , 43878008 English Streptococcal sore throat NOS , streptococcal sore throat , streptococcal sore throat (diagnosis) , Pharyngitis (...) streptococcal , Strep sore throat , Septic pharyngitis , strep throats , strept throat , streptococcal angina , streptococcus pharyngitis , Pharyngitis;streptococcal , Sore throat;streptococcal , septic sore throat , strep throat , Strep Throat , Streptococcal angina (disorder) , Streptococcal sore throat NOS (disorder) , Streptococcal pharyngitis (disorder) , Streptococcal sore throat , Streptococcal pharyngitis , Septic sore throat , Streptococcal angina , Strep throat , Strept throat , Streptococcal sore

2018 FP Notebook

195. Pharyngitis

Related Chapters II. Epidemiology One of four most common episodic clinic visit reasons III. Anatomy: Waldeyer's Tonsillar ring Nasopharynx Adenoids (pharyngeal s) at posterior wall Oropharynx Faucial ( s) at lateral wall) Hypopharynx Lingual at base IV. Causes See V. Symptoms Sore Throat (Difficulty swallowing) Odynophagia (pain with swallowing) ralized symptoms , Chills, Malaise or Symptoms suggestive of viral illness VI. Signs: Red flags (suggestive of serious cause) Unilateral Pharyngitis Toxic (...) , Zapalenie gardła Hungarian Pharyngealis gyulladás , pharyngitis k.m.n. , pharyngitis Norwegian Faryngitt , Svelgbetennelse Derived from the NIH UMLS ( ) Ontology: Sore Throat (C0242429) Definition (MEDLINEPLUS) Your throat is a tube that carries food to your esophagus and air to your windpipe and larynx (also called the voice box). The technical name for the throat is pharynx. You can have a sore throat for many reasons. Often, and cause sore throats. Other causes can include: Tonsillitis - an infection

2018 FP Notebook

196. The Clinical Presentation of Fusobacterium-Positive and Streptococcal-Positive Pharyngitis in a University Health Clinic: A Cross-sectional Study. (Abstract)

streptococcal pharyngitis and to determine whether F. necrophorum pharyngitis clinically resembles group A β-hemolytic streptococcal pharyngitis.Cross-sectional.University student health clinic.312 students aged 15 to 30 years presenting to a student health clinic with an acute sore throat and 180 asymptomatic students.Polymerase chain reaction testing from throat swabs to detect 4 species of bacteria and signs and symptoms used to calculate the Centor score.Fusobacterium necrophorum was detected in 20.5 (...) The Clinical Presentation of Fusobacterium-Positive and Streptococcal-Positive Pharyngitis in a University Health Clinic: A Cross-sectional Study. Pharyngitis guidelines focus solely on group A β-hemolytic streptococcal infection. European data suggest that in patients aged 15 to 30 years, Fusobacterium necrophorum causes at least 10% of cases of pharyngitis; however, few U.S. data exist.To estimate the prevalence of F. necrophorum; Mycoplasma pneumoniae; and group A and C/G β-hemolytic

2015 Annals of Internal Medicine

197. Hemifacial spasm caused by an aberrant jugular branch of the ascending pharyngeal artery. (Abstract)

Hemifacial spasm caused by an aberrant jugular branch of the ascending pharyngeal artery. We present the first report of a case of hemifacial spasm caused by an anomalous, enlarged branch of the ascending pharyngeal artery and treated with microvascular decompression. Clinicians must appreciate unusual causes of hemifacial spasm so that patients are not denied a curative operation due to atypical radiographic findings.

2014 British Journal of Neurosurgery

198. Causes and consequences of anterior pharyngeal pouch after total laryngectomy. Full Text available with Trip Pro

Causes and consequences of anterior pharyngeal pouch after total laryngectomy. To assess the frequency of anterior pharyngeal pouch formation after total laryngectomy, and to discuss the causes and consequences of anterior pharyngeal pouch formation.A prospective, observational study of 43 patients undergoing total laryngectomy.Data collected included laryngeal defect closure type, tumour staging and demographic information. A barium swallow was performed on day 7-14 after surgery to assess (...) for anterior pharyngeal pouch formation and fistula formation.The incidence of anterior pharyngeal pouch formation was 47 per cent. Patients who did not have an anterior pharyngeal pouch on swallow imaging assessment were less likely to develop a pharyngo-cutaneous fistula. There was no statistically significant association between laryngeal defect closure type and anterior pharyngeal pouch formation.The anterior pharyngeal pouch is a dynamic phenomenon best investigated with a fluoroscopic swallow imaging

2014 Journal of Laryngology & Otology

199. My approach to acute pharyngitis 2018

% of patients presenting with a sore throat complaint and leads to unnecessary antibiotics. This is the biggest mistake that I see! The controversy for adolescents/adults with pharyngitis and scores of 2-4 involves the concept of lack of proof. Why treat pharyngitis with antibiotics? There are 5 potential reasons: Prevent spread – untreated group A strep and group C/G strep can lead to infection in contacts. We have no data for Fusobacterium necrophorum Decrease duration of symptoms – in adults with scores (...) ). Adolescent pharyngitis: a review of bacterial causes. Clinical Pediatrics, 50(12), 1091–1095. http://doi.org/10.1177/0009922811409571 ) Here are the differences: Pre-adolescent pharyngitis really is group A strep vs viral Adolescent pharyngitis has a much broader differential – GAS, Group C/G strep, Fusobacterium necrophorum , infectious mononucleosis, acute HIV Antibiotics decrease duration of symptoms in adolescents but not pre-adolescents (Zwart, S., Sachs, A. P., Ruijs, G. J., Gubbels, J. W., Hoes

2018 db's Medical Rants blog

200. Compound motor action potential duration and latency are markers of recurrent laryngeal nerve injury. Full Text available with Trip Pro

Compound motor action potential duration and latency are markers of recurrent laryngeal nerve injury. Compound motor action potential (CMAP) can quantitatively evaluate innervation following injury to the recurrent laryngeal nerve (RLN) in canines. CMAP duration (the total time of CMAP) and latency (the time between the nerve impulse and the onset of action potentials) have not been assessed following RLN injury.Animal study.Twelve canine hemilaryngeal preparations were investigated. Baseline (...) % confidence interval [CI]: 0.43 to 2.40) and latency (2.6 ± 0.5 ms vs. 5.6 ± 1.5 ms, difference 3.0 ms 95% CI: 1.65 to 4.38). Stretch injuries also caused an increase in CMAP duration (2.3 ± 0.8 ms vs. 3.0 ± 0.6 ms, difference 0.7 ms 95% CI: -0.49 to 1.77) and latency (2.5 ± 0.8 ms vs. 4.7 ± 1.5 ms, difference 2.3 95% CI: 0.76 to 3.80). Using ROC curves, CMAP duration and latency differentiated between the baseline control and RLN injury at 6 months (area under the curve = 0.78 and 0.98, respectively

2017 Laryngoscope

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