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Pharmaceutical Representative

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81. Pharmaceutical care in Brazil’s primary health care (PubMed)

Pharmaceutical care in Brazil’s primary health care To characterize the activities of clinical nature developed by pharmacists in basic health units and their participation in educational activities aiming at health promotion.This article is part of the Pesquisa Nacional sobre Acesso, Utilização e Promoção do Uso Racional de Medicamentos - Serviços, 2015 (PNAUM - National Survey on Access, Use and Promotion of Rational Use of Medicines - Services, 2015), a cross-sectional and exploratory (...) study, of evaluative nature, consisting of a survey of information in a representative sample of cities, stratified by the Brazilian regions that constitute domains of study, and a subsample of primary health care services. The interviewed pharmacists (n=285) were responsible for the delivery of medicines and were interviewed in person with the use of a script. The characterization of the activities of clinical nature was based on information from pharmacists who declared to perform them

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2017 Revista de saúde pública

82. Access to medicines: relations with the institutionalization of pharmaceutical services (PubMed)

, exploratory, and evaluative study composed of an information survey in a representative sample of cities, stratified by Brazilian regions. Access was defined based on the acquisition of medicines reported by the patient, ranging between: total, partial, or null. The institutionalization of pharmaceutical services was analyzed based on information provided by pharmaceutical services providers and by those responsible for medicines delivery. Chi-square test and multinomial logistic regression were used (...) Access to medicines: relations with the institutionalization of pharmaceutical services To analyze the relationship between access to medicines by the population and the institutionalization of pharmaceutical services in Brazilian primary health care.This study is part of the Pesquisa Nacional sobre Acesso, Utilização e Promoção do Uso Racional de Medicamentos - Serviços 2015 (PNAUM - National Survey on Access, Use and Promotion of Rational Use of Medicines - Services 2015), a cross-sectional

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2017 Revista de saúde pública

83. Regulating the relationship between physicians and pharmaceutical companies: a qualitative and descriptive analysis of the impact of Israeli legislation (PubMed)

Regulating the relationship between physicians and pharmaceutical companies: a qualitative and descriptive analysis of the impact of Israeli legislation The Israeli National Health Insurance Law was amended in 2010 to require the disclosure of payments above 2500 NIS from pharmaceutical companies (PCs) to medical personnel and organizations. We examined if the law had an impact on the relationship between physicians in the Israeli health system and the pharmaceutical industry.We conducted 42 (...) in-depth semi-structured interviews with representatives of relevant stakeholders regarding the effects and extent of the law and the interviewees' attitudes about regulating the relationship between physicians and PCs. In addition, we analyzed reports on payments from PCs to various components of the health system.The majority of interviewees agreed that transparency is important to the relationship between PCs and physicians and none of them opposed the disclosure of payments. Most interviewees

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2017 Israel journal of health policy research

84. Simultaneous determination of cetirizine, phenyl propanolamine and nimesulide using third derivative spectrophotometry and high performance liquid chromatography in pharmaceutical preparations (PubMed)

Simultaneous determination of cetirizine, phenyl propanolamine and nimesulide using third derivative spectrophotometry and high performance liquid chromatography in pharmaceutical preparations The combination between cetirizine (CET), phenylpropanolamine (PPA) and nimesulide (NMS) under trade name Nemeriv Cp tablet is prescribed for nasal congestion, cold, sneezing, and allergy. Among all published methods for the three drugs; there is no reported method concerning estimation of CTZ, PPA (...) . The results were compared with those obtained from previously published methods and they were satisfactory. Graphical abstract Graphical abstract represents the chemical structures, representative chromatogram for the HPLC separation of a PPA, b NMS and c CTZ and third derivative absorption spectra of a PPA, b NMS and c CTZ for the spectrophotometric method.

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2017 Chemistry Central journal

85. Taking the lead from our colleagues in medical education: the use of images of the in-vivo setting in teaching concepts of pharmaceutical science (PubMed)

performance. Images formed through these techniques can provide students with a deeper appreciation of the fate of oral formulations in the body compared to standard disintegration and dissolution testing, which is conducted in-vitro. Such images which represent the in-vivo setting can be used in teaching to give context to both theory and experimental work, thereby increasing student understanding and enabling teaching of pharmaceutical sciences supporting students to correlate in-vitro and in-vivo (...) Taking the lead from our colleagues in medical education: the use of images of the in-vivo setting in teaching concepts of pharmaceutical science Despite pharmaceutical sciences being a core component of pharmacy curricula, few published studies have focussed on innovative methodologies to teach the content. This commentary identifies imaging techniques which can visualise oral dosage forms in-vivo and observe formulation disintegration in order to achieve a better understanding of in-vivo

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2017 Journal of pharmaceutical policy and practice

86. Jeffrey Aronson: When I use a word . . . “The pharmaceutical industry”—the definite article

that praise them or are neutral, and have found no definitions. In a few cases an index will cross-reference “pharmaceutical industry” to “drug companies”, but that’s as far as it goes. The website of the Association of the British Pharmaceutical Industry (ABPI) states that the association represents “innovative research based biopharmaceutical companies, large, medium, and small”, which could be taken as a definition. And the US Census Bureau the US pharmaceutical industry as “companies engaged (...) Jeffrey Aronson: When I use a word . . . “The pharmaceutical industry”—the definite article Jeffrey Aronson: When I use a word . . . “The pharmaceutical industry”—the definite article - The BMJ ---> A colleague recently asked me to point him to “an authoritative definition of ‘pharmaceutical industry’.” The term is one that few have tried to define, perhaps thinking that there is no need. I have searched the many books on my shelves that deal with the iniquities of drug companies, and the few

2016 The BMJ Blog

87. The 21st Century Cures Act passes, potentially turning the FDA into a puppet of the pharmaceutical industry

The 21st Century Cures Act passes, potentially turning the FDA into a puppet of the pharmaceutical industry The 21st Century Cures Act passes, potentially turning the FDA into a puppet of the pharmaceutical industry | ScienceBlogs Advertisment Search Search Toggle navigation Main navigation The 21st Century Cures Act passes, potentially turning the FDA into a puppet of the pharmaceutical industry By on December 7, 2016. Well, it’s done. Today, the , a bill designed to weaken the FDA and empower (...) pharmaceutical companies, sending it to President Obama’s desk. There’s no way Obama won’t sign it, as it contains provisions funding his Precision Medicine Initiative, and he supported it all along. For all its flaws, I knew the bill’s passage was inevitable since after the election, when Senate Majority Leader Mitch McConnell stated that the bill was a priority. I knew it even more when the Senate to the “ ” initiative spearheaded by Vice President Joe Biden in the wake of his son Beau’s death from brain

2016 Respectful Insolence

88. Pharmaceutical Sales Representatives and Patient Safety (PubMed)

Pharmaceutical Sales Representatives and Patient Safety 23884603 2014 06 20 2018 12 02 1525-1497 28 11 2013 Nov Journal of general internal medicine J Gen Intern Med Pharmaceutical sales representatives and patient safety. 1394 10.1007/s11606-013-2559-1 Light Donald W DW Edmond J. Safra Center for Ethics, Harvard University, Cambridge, MA, 02138, USA, dlight@ethics.harvard.edu. eng Letter Comment United States J Gen Intern Med 8605834 0884-8734 IM J Gen Intern Med. 2013 Oct;28(10):1368-75

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2013 Journal of General Internal Medicine

89. Pharmaceutical Sales Representatives and Patient Safety (PubMed)

Pharmaceutical Sales Representatives and Patient Safety 23897129 2014 06 20 2018 12 02 1525-1497 28 11 2013 Nov Journal of general internal medicine J Gen Intern Med Pharmaceutical sales representatives and patient safety. 1395 10.1007/s11606-013-2563-5 Mintzes Barbara B School of Population and Public Health, University of British Columbia, Vancouver, British Columbia, V6T 1Z3, Canada, Barbara.mintzes@ti.ubc.ca. Lexchin Joel J Wilkes Michael S MS Beaulieu Marie-Dominique MD Reynolds Ellen E

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2013 Journal of General Internal Medicine

90. Structured pharmaceutical representative interactions and counterdetailing sessions as components of medical resident education. (PubMed)

Structured pharmaceutical representative interactions and counterdetailing sessions as components of medical resident education. Educational activities should be developed to teach residents how to constructively interact with pharmaceutical representatives and how to critically assess the provided information.An educational study was implemented during the 2010-2011 academic year in an internal medicine residency program. The study included an initial educational session on physician-industry (...) relations and then 4 interactive sessions with the pharmaceutical representatives, each followed by a counterdetailing session provided by a clinical pharmacist. Study surveys were conducted to evaluate resident attitudes concerning pharmaceutical representative presented information before and after the counterdetailing sessions.A total of 27 residents (n = 27) participated in the study. The study results revealed that residents learned new relevant product information from the representatives (P

2013 Journal of pharmacy practice

91. Pharmaceutical Sales Representatives and Patient Safety: A Comparative Prospective Study of Information Quality in Canada, France and the United States. (PubMed)

Pharmaceutical Sales Representatives and Patient Safety: A Comparative Prospective Study of Information Quality in Canada, France and the United States. The information provided by pharmaceutical sales representatives has been shown to influence prescribing. To enable safe prescribing, medicines information must include harm as well as benefits. Regulation supports this aim, but relative effectiveness of different approaches is not known. The United States (US) and France directly regulate drug (...) claims or unapproved indications).Two hundred and fifty-five physicians reported on 1,692 drug-specific promotions. "Minimally adequate safety information" did not differ: 1.7 % of promotions; range 0.9-3.0 % per site. Sales representatives provided some vs. no information on harm more often in Toulouse than in Montreal and Vancouver: 61 % vs. 34 %, OR = 4.0; 95 % CI 2.8-5.6, or Sacramento (39 %), OR = 2.4; 95 % CI 1.7-3.6. Serious adverse events were rarely mentioned (5-6 % of promotions in all four

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2013 Journal of General Internal Medicine

92. Guideline-recommended vs high-dose long-term opioid therapy for chronic noncancer pain is associated with better health outcomes: data from representative sample of German population. (PubMed)

Guideline-recommended vs high-dose long-term opioid therapy for chronic noncancer pain is associated with better health outcomes: data from representative sample of German population. Recent evidence-based guidelines for long-term opioid therapy (LTOT) for chronic noncancer pain (CNCP) have defined daily morphine equivalent doses (MEQ/d) that require particular caution. The recommendation for a threshold MEQ/d is based on North American studies that have demonstrated negative health outcomes (...) associated with high-dose LTOT for CNCP. We have conducted a retrospective cross-sectional study using an anonymized German health claims database, including 4,028,618 persons insured by 69 German statutory health insurances, representative of age and sex for the German population in 2014. Those receiving German guideline-recommended opioid treatments (dose <120 mg MEQ/d) for CNCP were compared with those receiving high-dose LTOT (≥120 mg MEQ/d) for selected health outcomes (risky opioid prescribing

2017 Pain

93. 'At-risk' individuals' responses to direct to consumer advertising of prescription drugs: a nationally representative cross-sectional study. (PubMed)

'At-risk' individuals' responses to direct to consumer advertising of prescription drugs: a nationally representative cross-sectional study. The factors determining individuals' self-reported behavioural responses to direct to consumer advertising of prescription drugs were explored with an emphasis on 'at-risk' individuals' responses.Nationally representative cross-sectional survey.Community living adults in New Zealand.2057 adults (51% women).Self-reported behavioural responses to drug (...) . The outcomes raise significant concerns relating to the ethicality of drug advertising and suggest a need for stricter guidelines to ensure that drug advertisements provided by pharmaceutical companies are ethical.© Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

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2017 BMJ open

94. Living strategy of cold-adapted fungi with the reference to several representative species (PubMed)

functions in different ecosystems. Pseudogymnoascus destructans caused bat white-nose syndrome and Ophiocordyceps sinensis as Chinese medicine are the representative species that have significantly ecological and economic significance. Adaptation to cold niches has made this group of fungi a fascinating resource for the discovery of novel enzymes and secondary metabolites for biotechnological and pharmaceutical uses. This review provides the current understanding of living strategy and ecological (...) Living strategy of cold-adapted fungi with the reference to several representative species Our planet is dominant with cold environments that harbour enormously diverse cold-adapted fungi comprising representatives of all phyla. Investigation based on culture-dependent and independent methods has demonstrated that cold-adapted fungi are cosmopolitan and occur in diverse habitants and substrates. They live as saprobes, symbionts, plant and animal parasites and pathogens to perform crucial

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2017 Mycology

95. Serum matrix metalloproteinase-1 level represents disease activity as opposed to fibrosis in patients with histologically proven nonalcoholic steatohepatitis (PubMed)

Serum matrix metalloproteinase-1 level represents disease activity as opposed to fibrosis in patients with histologically proven nonalcoholic steatohepatitis Nonalcoholic steatohepatitis (NASH) is prevalent in both economically developed and developing countries. Twenty percent of NASH progresses to cirrhosis with/without hepatocellular carcinoma, and there is an urgent need to find biomarkers for early diagnosis and monitoring progression of the disease. Using immunohistochemical (...) and immunoelectron microscopic examination we previously reported that expression of matrix metalloproteinase-1 (MMP-1) increased in monocytes, Kupffer cells and hepatic stellate cells in early stage NASH. The present study investigated whether serum MMP-1 levels reflect disease activity and pharmaceutical effects in NASH patients.We measured the serum levels of MMPs, tissue inhibitors of metalloproteinases (TIMPs), and several cytokines/chemokines in patients with histologically proven early and advanced stages

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2017 Clinical and molecular hepatology

96. Managing Visits From Pharmaceutical Sales Representatives (PubMed)

Managing Visits From Pharmaceutical Sales Representatives 22876081 2012 10 02 2012 08 09 1052-1372 37 5 2012 May P & T : a peer-reviewed journal for formulary management P T Managing visits from pharmaceutical sales representatives. 261-3 Grissinger Matthew M eng Journal Article United States P T 9015516 1052-1372 2012 8 10 6 0 2012 8 10 6 0 2012 8 10 6 1 ppublish 22876081 PMC3411226

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2012 Pharmacy and Therapeutics

97. Pharmaceutical Representatives

Pharmaceutical Representatives Pharmaceutical Representatives Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Pharmaceutical (...) Representatives Pharmaceutical Representatives Aka: Pharmaceutical Representatives , Drug Rep , Prescribing Cost , Sunshine Act From Related Chapters II. Research: Studies Evaluation of 446 physicians surveyed Higher Prescribing Cost risks Pharmaceutical representative exposure Group practice setting References Direct drug advertising to healthcare consumers Appears to increase sale of drugs May result in appropriate prescribing practices Pharmaceutical samples raise overall Prescribing Costs Poorest patients

2015 FP Notebook

98. The assessment of pharmaceutical sales representatives by family physicians--does it affect the prescribing index? (PubMed)

The assessment of pharmaceutical sales representatives by family physicians--does it affect the prescribing index? Physicians' prescribing patterns depend on fixed and influence-sensitive factors. The latter include the influence of interactions with the pharmaceutical industry.To determine whether the assessment of pharmaceutical sales representatives (PSRs) by family physicians was associated with their actual prescribing index.Cross-sectional anonymous postal study. We included all family

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2012 Family Practice

99. Hidden drivers of low-dose pharmaceutical pollutant mixtures revealed by the novel GSA-QHTS screening method (PubMed)

an array of 180 unique low-dose mixtures, representing the most complex and data-rich experimental mixture effect assessment of main pharmaceutical pollutants to date. An ecological scaling-up experiment confirmed that this subset of pollutants also affects typical freshwater microbial community assemblages. Contrary to our expectations and challenging established scientific opinion, the bioactivity of the mixtures was not predicted by the null mixture models, and the main drivers that were identified (...) Hidden drivers of low-dose pharmaceutical pollutant mixtures revealed by the novel GSA-QHTS screening method The ecological impacts of emerging pollutants such as pharmaceuticals are not well understood. The lack of experimental approaches for the identification of pollutant effects in realistic settings (that is, low doses, complex mixtures, and variable environmental conditions) supports the widespread perception that these effects are often unpredictable. To address this, we developed

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2016 Science advances

100. Occurrence and transformation of veterinary pharmaceuticals and biocides in manure: a literature review (PubMed)

Occurrence and transformation of veterinary pharmaceuticals and biocides in manure: a literature review The spread of veterinary medicinal products (VMPs) and biocides via manure onto agriculturally used areas represents a very important emission into the environment for these product groups. Within this literature study, publicly available transformation studies with liquid manure are summarized. Transformation studies were evaluated regarding the transformation fate of tested substances

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2016 Environmental Sciences Europe

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