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1. Pesticide residues in food - 2016: toxicological evaluations/Special session of the Joint meeting of the FAO Panel of Experts on Pesticide Residues in Food and the Environment and the WHO Core Assessment Group on Pesticide Residues, Geneva, Switzerland, 9

Pesticide residues in food - 2016: toxicological evaluations/Special session of the Joint meeting of the FAO Panel of Experts on Pesticide Residues in Food and the Environment and the WHO Core Assessment Group on Pesticide Residues, Geneva, Switzerland, 9 Pesticide residues in food - 2016: toxicological evaluations/Special session of the Joint meeting of the FAO Panel of Experts on Pesticide Residues in Food and the Environment and the WHO Core Assessment Group on Pesticide Residues, Geneva (...) , Switzerland, 9–13 May 2016 JavaScript is disabled for your browser. Some features of this site may not work without it. Toggle navigation Toggle navigation Search Browse Statistics Related Links Pesticide residues in food - 2016: toxicological evaluations/Special session of the Joint meeting of the FAO Panel of Experts on Pesticide Residues in Food and the Environment and the WHO Core Assessment Group on Pesticide Residues, Geneva, Switzerland, 9–13 May 2016 View/ Open View Statistics Altmetrics Share

2017 WHO

2. Pesticide distribution and depletion kinetic determination in honey and beeswax: Model for pesticide occurrence and distribution in beehive products. (PubMed)

Pesticide distribution and depletion kinetic determination in honey and beeswax: Model for pesticide occurrence and distribution in beehive products. Beehive products such as honey, beeswax and recently pollen have been regarded for many years as appropriate sentinels for environmental pesticide pollutions. However, despite yearly application of hundreds of approved pesticides in agricultural fields, only a minor fraction of these organic compounds were actually detected in honey and beeswax (...) samples. This observation has led us to question the general suitability of beehive products as a sentinel for synthetic organic pesticides applied in the field. The aim of the present study was to experimentally determine the distribution (logarithmic ratio of beeswax to honey pesticide concentration, LogD) and depletion kinetics (half-life) of selected pesticides in honey and beeswax as a measure of the latter matrixes to serve as a pesticide sentinel. The obtained parameters were used

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2019 PLoS ONE

3. Effectiveness of household lockable pesticide storage to reduce pesticide self-poisoning in rural Asia: a community-based, cluster-randomised controlled trial. (PubMed)

Effectiveness of household lockable pesticide storage to reduce pesticide self-poisoning in rural Asia: a community-based, cluster-randomised controlled trial. Agricultural pesticide self-poisoning is a major public health problem in rural Asia. The use of safer household pesticide storage has been promoted to prevent deaths, but there is no evidence of effectiveness. We aimed to test the effectiveness of lockable household containers for prevention of pesticide self-poisoning.We did (...) a community-based, cluster-randomised controlled trial in a rural area of North Central Province, Sri Lanka. Clusters of households were randomly assigned (1:1), with a sequence computer-generated by a minimisation process, to intervention or usual practice (control) groups. Intervention households that had farmed or had used or stored pesticide in the preceding agricultural season were given a lockable storage container. Further promotion of use of the containers was restricted to community posters and 6

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2017 Lancet Controlled trial quality: predicted high

4. CRACKCast E163 – Pesticides

CRACKCast E163 – Pesticides CRACKCast E163 – Pesticides - CanadiEM CRACKCast E163 – Pesticides In , by Chris Lipp March 15, 2018 This episode of CRACKCast covers Rosen’s 9th Edition Chapter 163, Pesticides. These agents have unique presentations and management principles that this episode will go over. They are very important not to miss! Shownotes – PDF Key concepts: Organophosphates and carbamates cause symptoms by accumulation of acetylcholine. Treat cholinergic symptoms with atropine (...) not be used in infants younger than 2 months old. DEET in concentrations of more than 30% should not be used in children and may result in neurotoxicity and self-limited seizure activity if used in excessive amounts. Most rodenticide exposures will be superwarfarin compounds. For large exposures, INR should be checked at a minimum of 2 days after ingestion. Vitamin K should be used for reversal; blood products should be used for active bleeding. Rosen’s In Perspective Pesticide is a general term

2018 CandiEM

5. Global capacity for vector control and product testing: report of the tenth meeting of the global collaboration for development of pesticides for public health, 20-21 September 2016, Hotel Royal, Geneva, Switzerland

Global capacity for vector control and product testing: report of the tenth meeting of the global collaboration for development of pesticides for public health, 20-21 September 2016, Hotel Royal, Geneva, Switzerland Global capacity for vector control and product testing: report of the tenth meeting of the global collaboration for development of pesticides for public health, 20-21 September 2016, Hotel Royal, Geneva, Switzerland JavaScript is disabled for your browser. Some features (...) of this site may not work without it. Toggle navigation Toggle navigation Search Browse Statistics Related Links Global capacity for vector control and product testing: report of the tenth meeting of the global collaboration for development of pesticides for public health, 20-21 September 2016, Hotel Royal, Geneva, Switzerland View/ Open Rights View Statistics Altmetrics Share Citation World Health Organization . (‎2017)‎. Global capacity for vector control and product testing: report of the tenth meeting

2017 WHO

6. Manuel sur l’élaboration et l’utilisation des spécifications FAO/OMS pour les pesticides

Manuel sur l’élaboration et l’utilisation des spécifications FAO/OMS pour les pesticides Manuel sur l’élaboration et l’utilisation des spécifications FAO/OMS pour les pesticides JavaScript is disabled for your browser. Some features of this site may not work without it. Toggle navigation Toggle navigation Search Browse Statistics Related Links Manuel sur l’élaboration et l’utilisation des spécifications FAO/OMS pour les pesticides, Première éd., troisième révision View/ Open View Statistics (...) Altmetrics Share Citation Organisation mondiale de la Santé & Organisation des Nations Unies pour l’alimentation et l’agriculture . (‎2017)‎. Manuel sur l’élaboration et l’utilisation des spécifications FAO/OMS pour les pesticides, Première éd., troisième révision. Organisation mondiale de la Santé. Description xv, 318 p. Gov't Doc # WHO/HTM/NTD/WHOPES/2016.4 ISBN 9789252092650 (‎FAO)‎ ISSN 1014-1219 Other Language Versions Collections Language français Metadata Related items Showing items related

2017 WHO

7. Pesticides: a toxic issue

Pesticides: a toxic issue Prescrire IN ENGLISH - Spotlight ''Pesticides: a toxic issue'', 1 March 2016 {1} {1} {1} | | > > > Pesticides: a toxic issue Spotlight Every month, the subjects in Prescrire’s Spotlight. 100 most recent :  |   |   |   |   |   |   |   |   |  Spotlight Pesticides: a toxic issue Pesticides have a lot in common with pharmaceuticals: poorly evaluated or exaggerated efficacy, products marketed without (...) sufficient knowledge of the risks, research financed by the manufacturers. In January 2013, the European Food Safety Authority concluded that the use of pesticides containing 3 neonicotinoids represented a danger to bees. Following this report, the European Commission suspended the use of these pesticides on the crops most attractive to bees in 2014 and 2015. They did so even though the pesticide industry had lobbied intensively against the ban on neonicotinoids. One of the initiatives of the pesticide

2016 Prescrire

8. Vendor-based restrictions on pesticide sales to prevent pesticide self-poisoning - a pilot study. (PubMed)

Vendor-based restrictions on pesticide sales to prevent pesticide self-poisoning - a pilot study. In South Asia, up to 20% of people ingesting pesticides for self-poisoning purchase the pesticide from a shop with the sole intention of self-harm. Individuals who are intoxicated with alcohol and/or non-farmers represent 72% of such high-risk individuals. We aimed to test the feasibility and acceptability of vendor-based restrictions on pesticide sales for such high-risk individuals.We conducted (...) a pilot study in 14 (rural = 7, urban = 7) pesticide shops in Anuradhapura District of Sri Lanka. A two-hour training program was delivered to 28 pesticide vendors; the aim of the training was to help vendors recognize and respond to customers at high risk of pesticide self-poisoning. Knowledge and attitudes of vendors towards preventing access to pesticides for self-poisoning at baseline and in a three month follow-up was evaluated by questionnaire. Vendors were interviewed to explore the practice

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2018 BMC Public Health

9. The Burden of Acute Pesticide Poisoning and Pesticide Regulation in Korea (PubMed)

The Burden of Acute Pesticide Poisoning and Pesticide Regulation in Korea This study aimed to estimate the burden of acute pesticide poisoning and to determine its trend with recently implemented pesticide regulations.Disability-adjusted life-years (DALYs) were calculated as the sum of years of life lost (YLLs) and years lived with disability (YLDs) due to acute pesticide poisoning using the methods of the Global Burden of Disease Study 2013. The values of YLLs, YLDs, and DALYs were stratified (...) by sex, age groups, intentionality of poisoning, and causative agents.From 2006 to 2014, DALYs decreased by 69% (from 69,550 to 21,742). The decreasing tendency of DALYs was especially marked from 2011. The total burden of acute pesticide poisoning was mainly caused by YLLs and intentional pesticide poisoning. The highest DALYs due to acute pesticide poisoning occurred in those in their 40s and 50s; however, the decreased rates of DALYs were higher in those aged 10-49 years than in those aged more

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2018 Journal of Korean medical science

10. Prospective Investigation of Pesticide Applicators' Health (PIPAH) study: a cohort study of professional pesticide users in Great Britain. (PubMed)

Prospective Investigation of Pesticide Applicators' Health (PIPAH) study: a cohort study of professional pesticide users in Great Britain. The purpose of the study is to monitor the exposure and health of workers in Great Britain who use pesticides as a part of their job, and to gain a better understanding of the relationship between long-term exposure to pesticides and health.Study participants are professional pesticide users who are certified in the safe use of pesticides or who were born (...) before 1965 and apply pesticides under 'grandfather rights'. Overall response rate was 20%; participants are mostly male (98%) and the average age is 54 years, ranging from 17 to over 80 years.Participants have completed a baseline general questionnaire and three follow-up questionnaires on the use of pesticides. These data will enable investigations into the relationship between occupational pesticide exposure and health outcomes taking into account non-occupational confounding factors.There

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2017 BMJ open

11. Pesticide metabolite and oxidative stress in male farmers exposed to pesticide (PubMed)

Pesticide metabolite and oxidative stress in male farmers exposed to pesticide The objective of this study was to measure malondialdehyde (MDA) and isoprostane which has been used as an index of lipid injury, 8-hydroxy-2'-deoxyguanosine (8-OHdG), which has been used as an index of DNA damage, and dialkyl-phosphate (DAP), which has been used to quantify pesticide exposure, and to investigate the relationship between pesticide exposure and oxidative stress.This study was a cross-sectional study (...) that evaluated 84 male farmers exposure to pesticide. In this study, 8-OHdG, isoprostane, and MDA were measured as oxidative stress indices, and dialkyl-phosphate (dimethylphosphate(DMP), diethylphosphate(DEP), dimethylthiophosphate(DMTP), and diethylthiophosphate (DETP)) excreted in the urine was also measured to evaluate pesticide exposure. A linear regression analysis was performed to investigate the relationship between pesticide metabolites, and oxidative stress biomarkers.A Correlation analysis

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2017 Annals of occupational and environmental medicine

12. Risk Factors of Pesticide Poisoning and Pesticide Users’ Cholinesterase Levels in Cotton Production Areas: Glazoué and Savè Townships, in Central Republic of Benin (PubMed)

Risk Factors of Pesticide Poisoning and Pesticide Users’ Cholinesterase Levels in Cotton Production Areas: Glazoué and Savè Townships, in Central Republic of Benin To assess the degree of poisoning in farmers using the erythrocyte acetylcholinesterase (AChE) test before and after the exposure to pesticides in townships in central Benin (Glazoué and Savè) and to identify the associated risk factors.Using a cross-sectional study design, we recruited 264 farm pesticide sprayers, who have been (...) working for at least 5 years. They completed a questionnaire and underwent the AChE test using the Test-mate Model 400 device (EQM Research Inc.) with a photometric sensor, based on the works of Ellman.Organophosphate/pyrethroids were the most common pesticides used by at least 72.96% of the farmworkers. We observed an inhibition of AChE between pre-exposure and post-exposure (P = .002) for 60.61% of the farmworkers. Among them, 11.88% displayed more than 20% AChE inhibition.Pesticide poisoning

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2017 Environmental health insights

13. Pesticide use and LINE-1 methylation among male private pesticide applicators in the Agricultural Health Study (PubMed)

Pesticide use and LINE-1 methylation among male private pesticide applicators in the Agricultural Health Study Cancer risk may be associated with DNA methylation (DNAm) levels in Long Interspersed Nucleotide Element 1 (LINE-1), a surrogate for global DNAm. Exposure to certain pesticides may increase risk of particular cancers, perhaps mediated in part through global DNAm alterations. To date, human data on pesticide exposure and global DNAm alterations are limited. The goal of this study (...) was to evaluate alterations of LINE-1 DNAm by pesticides in a variety of classes. Data from 596 cancer-free male participants enrolled in the Agricultural Health Study (AHS) were used to examine associations between use of 57 pesticides and LINE-1 DNAm measured via Pyrosequencing in peripheral blood leucocytes. Participants provided information on pesticide use at three contacts between 1993 and 2010. Associations of ever/never pesticide use and lifetime days of application (years of use × days per year

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2017 Environmental Epigenetics

14. Increased Frequency of Rheumatoid Arthritis and Allergic Rhinitis among Pesticide Sprayers and Associations with Pesticide Use (PubMed)

Increased Frequency of Rheumatoid Arthritis and Allergic Rhinitis among Pesticide Sprayers and Associations with Pesticide Use Objective: The aim of this study was to identify diseases linked with the pesticide sprayer occupation and explore possible associations with exposure history data. Methods: Α cross sectional study was conducted among pesticide sprayers (n = 80) and the general population (n = 90) in Thessaly (Greece). Medical history, demographic characteristics and detailed exposure (...) history were recorded by conducting personal interviews. Lifetime exposure indicators were calculated for several pesticide chemical subclasses. Moreover, organophosphate metabolite levels were quantified in urine samples of all participants by using gas chromatography -mass spectrometry (GC-MS). Multinomial analysis was used to determine associations between occupational pesticide exposure and diseases or disorders. Results: In the pesticide sprayers group, significantly higher frequencies

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2017 International journal of environmental research and public health

15. The impact of repeated organophosphorus pesticide exposure on biomarkers and neurobehavioral outcomes among adolescent pesticide applicators (PubMed)

The impact of repeated organophosphorus pesticide exposure on biomarkers and neurobehavioral outcomes among adolescent pesticide applicators Egyptian adolescents are hired as seasonal workers to apply pesticides to the cotton crop and may perform this occupation for several years. However, few studies examined the effects of repeated pesticide exposure on health outcomes The goal of this study was to determine the impact of repeated pesticide exposure on neurobehavioral (NB) performance (...) and biomarkers of exposure (urinary metabolite) and effect (cholinesterase activity). Eighty-four adolescents from two field stations in Menoufia, Egypt, were examined four times: before and during pesticide application season in 2010 and again before and during application season in 2011. At each of the four time points, participants completed a questionnaire, performed an NB test battery, and were assessed for urinary levels of the chlorpyrifos metabolite TCPy (3,5,6-trichloro-2-pyridinol) and blood

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2017 Journal of toxicology and environmental health. Part A

16. Pesticide Exposure and Risk of Rheumatoid Arthritis among Licensed Male Pesticide Applicators in the Agricultural Health Study (PubMed)

Pesticide Exposure and Risk of Rheumatoid Arthritis among Licensed Male Pesticide Applicators in the Agricultural Health Study The occupation of farming has been associated with rheumatoid arthritis (RA); pesticides may account for this association, but there are few studies.We investigated associations between RA and use of pesticides in the Agricultural Health Study.The study sample was drawn from male pesticide applicators enrolled in 1993–1997 who provided questionnaire data at baseline (...) and at least once during follow-up (over a median 18 y; interquartile range 16–19). Incident RA cases (n=220), confirmed by physicians or by self-reported use of disease-modifying antirheumatic drugs, were compared with noncases (n=26,134) who did not report RA. Odds ratios (ORs) and 95% confidence intervals (CIs) were estimated using logistic regression, adjusting for enrollment age, state, smoking pack-years, and education. We evaluated the association of RA with the use of 46 pesticides and across 4

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2017 Environmental health perspectives

17. Elevated Levels of Organochlorine Pesticides in South Asian Immigrants Are Associated With an Increased Risk of Diabetes (PubMed)

Elevated Levels of Organochlorine Pesticides in South Asian Immigrants Are Associated With an Increased Risk of Diabetes Rates of diabetes mellitus are higher in South Asians than in other populations and persist after migration. One unexplored cause may be higher exposure to persistent organic pollutants associated with diabetes in other populations. We compared organochlorine (OC) pesticide concentrations in South Asian immigrants and European whites to determine whether the disease (...) was positively associated with OC pesticides in South Asians.South Asians of Tamil or Telugu descent (n = 120) and European whites (n = 72) were recruited into the London Life Sciences Population Study cohort. Blood samples as well as biometric, clinical, and survey data were collected. Plasma levels of p,p'-dichlorodiphenyldichloroethylene (DDE), p,p'- dichlorodiphenyltrichloroethane, β-hexachlorohexane (HCH), and polychlorinated biphenyl-118 were analyzed by gas chromatography-mass spectrometry. South

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2018 Journal of the Endocrine Society

18. Why Regulators Lost Track and Control of Pesticide Risks: Lessons From the Case of Glyphosate-Based Herbicides and Genetically Engineered-Crop Technology (PubMed)

Why Regulators Lost Track and Control of Pesticide Risks: Lessons From the Case of Glyphosate-Based Herbicides and Genetically Engineered-Crop Technology The approval of genetically engineered (GE) crops in the late 1990s triggered dramatic changes in corn, soybean, and cotton pest management systems, as well as complex, novel regulatory challenges. Lessons learned are reviewed and solutions described.Government-imposed resistance management provisions can work and adapt to changing (...) circumstances, but within the private sector, pressures to gain and hold market share have thus far trumped the widely recognized need for resistance management. Risks arising from the use of formulated pesticides often exceed by a wide margin those in regulatory risk assessments based on data derived from studies on nearly 100% pure active ingredients. Innovative policy changes are needed in four problem areas: excessive faith in the accuracy of pre-market risk assessments and regulatory thresholds; post

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2018 Current environmental health reports

19. Spodoptera frugiperda Smith (Lepidoptera: Noctuidae) in Cameroon: Case study on its distribution, damage, pesticide use, genetic differentiation and host plants. (PubMed)

Spodoptera frugiperda Smith (Lepidoptera: Noctuidae) in Cameroon: Case study on its distribution, damage, pesticide use, genetic differentiation and host plants. Maize farmers in sub-Saharan Africa recently experienced unusual damage in their farms, attributed to the fall armyworm (FAW) Spodoptera frugiperda (J. E. Smith). This pest was first recorded in Africa in 2016, but detailed information on its distribution and damage and farmer's response in invaded areas are largely lacking (...) stemborers on the same plants, suggesting possible direct and/or indirect competition between the two groups of maize pests. In response to this new threat to maize production, farmers have opted for the application of synthetic pesticides. Although our experiments were not designed to determine pesticide efficacy, as parameters such as time since application were not considered, our observations suggest lack of a drastic effect on S. frugiperda infestations on maize. There were two haplotypes of FAW co

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2019 PLoS ONE

20. Correction: Pesticide exposure and cognitive decline in a rural South Korean population. (PubMed)

Correction: Pesticide exposure and cognitive decline in a rural South Korean population. [This corrects the article DOI: 10.1371/journal.pone.0213738.].

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2019 PLoS ONE

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