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Peripheral Arterial Disease 10-Year Mortality Index

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1. Changes in exercise capacity and risk of all-cause mortality in patients with peripheral artery disease: a 10-year retrospective cohort study. (Abstract)

Changes in exercise capacity and risk of all-cause mortality in patients with peripheral artery disease: a 10-year retrospective cohort study. We retrospectively studied the association between changes in exercise capacity at discharge from a home-based exercise program and the risk of all-cause mortality among patients with peripheral artery disease (PAD) and claudication. The records of 1076 consecutive PAD patients were assessed between 2003 and 2013. The exercise program was prescribed (...) during a few visits and executed at home at symptom-free walking speed. Ankle-Brachial Index (ABI) and maximal speed (Smax) on an incremental treadmill test were recorded at baseline and discharge. The number and date of deaths and hospitalizations for a 10-year period were collected from the regional registry. A total of 865 PAD patients completed the program (completers), while 221 left the program for health reasons (n = 128, diseased) or for nonhealth reasons (n = 83, quitters). Among

2019 Internal and emergency medicine

2. The heart matters in diabetes: 10-Year outcomes of peripheral artery disease Full Text available with Trip Pro

, and admitted to a tertiary care hospital. Our cohort included 216 patients without diabetes mellitus and 115 with diabetes mellitus. The outcome measure was all-cause mortality at 10years post-admission.Mortality rates at 10years were 29% among non-diabetic peripheral arterial disease patients and 58% among diabetic peripheral arterial disease patients. We identified the following independent predictors of death in the 216 peripheral arterial disease patients without diabetes: age ≥65 years (risk ratio (...) The heart matters in diabetes: 10-Year outcomes of peripheral artery disease Mortality rates at 10years are higher in diabetic patients with chronic lower extremity peripheral arterial disease than in non-diabetic peripheral arterial disease patients. We tested the hypothesis that the predictors of mortality differ between diabetic and non-diabetic peripheral arterial disease patients.We studied 331 consecutive patients who were <75 years of age, symptomatic for peripheral arterial disease

2017 SAGE open medicine

3. Diagnosis and Treatment of Peripheral Arterial Diseases Full Text available with Trip Pro

syndrome 799 11. Multisite artery disease 799 11.1 Multisite artery disease: epidemiology and impact prognosis 800 11.2 Screening for and management of multisite artery disease 800 11.2.1 Peripheral arterial diseases in patients presenting with coronary artery disease 800 11.2.2. Coronary artery disease in patients presenting with peripheral arterial diseases 803 11.2.3 Other peripheral localizations in patients with peripheral arterial diseases 804 12. Cardiac conditions in peripheral arterial (...) arterial diseases and vascular access site for cardiac interventions 806 13. Gaps in evidence807 14. To do and not to do messages from the Guidelines 808 15. Web addenda and companion document 811 16. Appendix 811 17. References 811 Abbreviations and acronyms Abbreviations and acronyms Abbreviations and acronyms AAA Abdominal aorta aneurysm ABI Ankle-brachial index ACAS Asymptomatic Carotid Atherosclerosis Study ACEIs Angiotensin-converting enzyme inhibitors ACS Acute coronary syndrome ACSRS

2017 European Society of Cardiology

4. 2016 AHA/ACC Guideline on the Management of Patients With Lower Extremity Peripheral Artery Disease

to activity level or present at rest Modified from Norgren L et al. 35 PAD indicates peripheral artery disease. Table 7. Alternative Diagnoses for Nonhealing Wounds With Normal Physiological Testing (Not PAD-Related) Condition Location Characteristics and Causes Venous ulcer Distal leg, especially above medial mellolus Develops in regions of skin changes due to chronic venous disease and local venous hypertension Typically wet (ie, wound drainage) rather than dry lesion Distal small arterial occlusion (...) ://ahajournals.org by on March 27, 2019Gerhard-Herman et al March 21, 2017 Circulation. 2017;135:e726–e779. DOI: 10.1161/CIR.0000000000000471 e738 Figure 1. Diagnostic Testing for Suspected PAD. Colors correspond to Class of Recommendation in Table 1? ABI indicates ankle-brachial index; CLI, critical limb ischemia; CTA, computed tomography angiography; GDMT, guideline-directed management and therapy; MRA, magnetic resonance angiography; PAD, peripheral artery disease; and TBI, toe-brachial index? Autoimmune

2017 American Heart Association

5. Lower Extremity Peripheral Artery Disease: Guideline on the Management of Patients With

. JACC VOL. 69, NO. 11, 2017 Gerhard-Herman et al. MARCH 21, 2017:e71–126 2016 AHA/ACC Lower Extremity PAD Guideline e83FIGURE 1 Diagnostic Testing for Suspected PAD Colors correspond to Class of Recommendation in Table 1. ABIindicatesankle-brachialindex;CLI,criticallimbischemia;CTA,computedtomographyangiography;GDMT,guideline-directedmanagementandtherapy; MRA, magnetic resonance angiography; PAD, peripheral artery disease; and TBI, toe-brachial index. Gerhard-Herman et al. JACC VOL. 69, NO. 11, 2017 (...) Lower Extremity Peripheral Artery Disease: Guideline on the Management of Patients With CLINICAL PRACTICE GUIDELINE 2016 AHA/ACC Guideline on the Management of Patients With Lower Extremity Peripheral Artery Disease A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines Developed in Collaboration With the American Association of Cardiovascular and Pulmonary Rehabilitation, Inter-Society Consensus for the Management of Peripheral

2016 American College of Cardiology

6. Acute Limb Ischemia in Peripheral Artery Disease: Insights from EUCLID. (Abstract)

Acute Limb Ischemia in Peripheral Artery Disease: Insights from EUCLID. Acute limb ischemia (ALI) is an important clinical event and an emerging cardiovascular clinical trial outcome. Risk factors for and outcomes after ALI have not been fully evaluated.EUCLID randomized patients with peripheral artery disease (PAD) to ticagrelor versus clopidogrel. Enrollment criteria included an ankle-brachial index (ABI) ≤0.80 or prior lower extremity revascularization. Patients were grouped according (...) to the primary outcome, post-randomization ALI hospitalization. Baseline factors associated with ALI were identified using Cox proportional hazards modeling. Models with ALI hospitalization as a time-dependent covariate were developed for secondary outcomes of major adverse cardiovascular events (MACE: myocardial infarction, cardiovascular death, ischemic stroke), all-cause mortality, and major amputation.Among 13,885 patients, 1.7% (n=232) had 293 ALI hospitalizations (0.8 per 100 patient-years). Patients

2019 Circulation Controlled trial quality: predicted high

7. Cell Therapy for Peripheral Arterial Disease and Diabetes

Detailed Description: INTRODUCTION: Peripheral arterial disease (PAD) is defined as arterial occlusion of the lower extremities. Based on epidemiological studies using the Ankle-Brachial Index (ABI), the prevalence of PAD (defined as an ABI <0.9) in diabetic patients ranges from 20% to 30%. Diabetic patients with PAD have a higher mortality and death rate at a younger age than patients without diabetes. The appropriate medical treatment for EAP in patients with diabetes is based on the control (...) Institute of Social Security. Patients older than 35 years. Patients with Type 2 Diabetes Mellitus over 10 years of detection. Patients with Peripheral Arterial Disease with ABI between 0.6 and 0.9. Signature of informed consent. Exclusion Criteria: Patients with a history of uncontrolled oncological disease in the last 5 years. Presence of Chronic Renal Insufficiency with a calculated creatinine clearance using a Cockcroft formula less than 15ml / min. Ulcer that defines diabetic foot or tissue

2018 Clinical Trials

8. Carotid Artery Reactivity Predicts Events in Peripheral Arterial Disease Patients. Full Text available with Trip Pro

the necessity for simple assessment of endothelial function.A total of 172 PAD patients (68 ± 10 years, 67% male) underwent the CAR, which involves ultrasound measurement of carotid artery diameter during sympathetic stimulation produced by 90-second hand immersion in 4°C ice-water (ie, cold pressor test). CAR-responses were dichotomized into carotid constriction or dilation. We recorded cardiac and cerebrovascular events, mortality, and clinical progression to percutaneous transluminal angioplasty or loss (...) Carotid Artery Reactivity Predicts Events in Peripheral Arterial Disease Patients. Patients with peripheral arterial disease (PAD) have increased risk on future cerebro- and cardiovascular events. Our aim was to examine whether carotid artery reactivity (CAR; a novel, simple procedure to examine endothelial function) predicts cardiovascular events in PAD patients.Increased risk for future cardiovascular events in PAD patients is likely related to endothelial dysfunction, highlighting

2017 Annals of Surgery

9. Lower Extremity Peripheral Arterial Disease Is an Independent Predictor of Coronary Heart Disease and Stroke Risks in Patients with Type 2 Diabetes Mellitus in China Full Text available with Trip Pro

Lower Extremity Peripheral Arterial Disease Is an Independent Predictor of Coronary Heart Disease and Stroke Risks in Patients with Type 2 Diabetes Mellitus in China We aimed to determine the relationship between lower extremity peripheral arterial disease (PAD), 10-year coronary heart disease (CHD), and stroke risks in patients with type 2 diabetes (T2DM) using the UKPDS risk engine. We enrolled 1178 hospitalized T2DM patients. The patients were divided into a lower extremity PAD group (ankle (...) -brachial index ≤ 0.9 or >1.4; 88 patients, 7.5%) and a non-PAD group (ankle-brachial index > 0.9 and ≤1.4; 1090 patients, 92.5%). Age; duration of diabetes; systolic blood pressure; the hypertension rate; the use of hypertension drugs, ACEI /ARB, statins; CHD risk; fatal CHD risk; stroke risk; and fatal stroke risk were significantly higher in the PAD group than in the non-PAD group (P < 0.05 for all). Logistic stepwise regression analysis indicated that ABI was an independent predictor of 10-year CHD

2017 International journal of endocrinology

10. Peripheral arterial disease. Diagnosis and management in general practice

Peripheral arterial disease. Diagnosis and management in general practice clinical are less intensively treated. 6 Both asymptomatic and symptomatic PAD patients have a high risk of death from cardiovascular disease (CVD), 2,7 therefore early treatment reduces mortality. 8 Screening for PAD in general practice Screening for PAD using the ankle-brachial index (ABI) or questionnaire is not currently recommended in Australia, and has not been shown to be of benefit in randomised controlled trials (...) . 7. Criqui M, langer R, Fronek A, et al., Mortality over a period of 10 years in patients with peripheral artery disease. n engl j Med 1992;326:326–81. 8. Aung PP, Maxwell hG, jepson RG, Price jF, leng GC. lipid-lowering for peripheral arterial disease of the lower limb. Cochrane Database Syst Rev 2007;4:CD000123. 9. Ferket B, Spronk S, Colkesen e, hunink M. Systematic review of guidelines on periph- eral artery disease screening. Am j Med 2012;125:198–208. 10. Rooke T, hirsch A, Misra S, et al

2013 Clinical Practice Guidelines Portal

11. Evaluate the Correlation of NIRS, ABI, Exercise, baPWV and Albuminuria With Peripheral Artery Occlusion Disease (PAD) and Other Atherosclerosis Outcomes

of baPWV, ABI and microalbuminuria after managing the atherosclerosis risks, and analyze their influence on the outcome of PAD, coronary artery disease(CAD) and cerebral vascular disease(CVA) outcomes. Condition or disease Intervention/treatment Diabetes Peripheral Arterial Occlusive Disease Device: oscillometric (Omron Colin co) Detailed Description: Exercise testing by Active Pedal Plantar flexion: The investigators plan to collect 140 cases: Healthy subjects with no apparent atherosclerotic risk (...) Evaluate the Correlation of NIRS, ABI, Exercise, baPWV and Albuminuria With Peripheral Artery Occlusion Disease (PAD) and Other Atherosclerosis Outcomes Evaluate the Correlation of NIRS, ABI, Exercise, baPWV and Albuminuria With Peripheral Artery Occlusion Disease (PAD) and Other Atherosclerosis Outcomes - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail

2017 Clinical Trials

12. Stable Coronary Artery Disease (2nd Edition)

Management 91 11. FOLLOW-UP OF PATIENTS WITH STABLE CAD 93 12. PRE-OPERATIVE ASSESSMENT FOR ELECTIVE NON-CARDIAC SURGERY 95 13. MONITORING AND QUALITY ASSURANCE 97 REFERENCES 98 ACKNOWLEDGMENTS 123 DISCLOSURE STATEMENT 123 SOURCES OF FUNDING 123 6 Rationale: Coronary Artery Disease (CAD) covers a wide spectrum from asymptomatic individuals to patients with stable CAD, Acute Coronary Syndromes (ACS) and Sudden Cardiac Death (SCD). This Clinical Practice Guidelines (CPG) on Stable CAD is directed (...) Inhibitor ACS Acute Coronary Syndrome AF Atrial Fibrillation AHA/ACC American Heart Association/american College Of Cardiology ARB Angiotensin Receptor Blocker ATP Adenosine Triphosphate BMI Body Mass Index BMT Behavioural Modification Therapy BP Blood Pressure CABG Coronary Artery Bypass Surgery CAD Coronary Artery Disease CAC Coronary Calcium Score CASS Coronary Artery Surgery Study CCB Calcium Channel Blockers CCS Canadian Cardiovascular Society CHF Congestive Heart Failure CHO Carbohydrate CKD

2018 Ministry of Health, Malaysia

13. The 2016 International Society for Heart Lung Transplantation listing criteria for heart transplantation: A 10-year update

of stroke and functional decline after transplantation independent of other variables, but not death, during long-term follow-up. This study suffers from the potential for misclassi?cation, and indeed, some patients may have undergone revascula- rization, which could have modi?ed their risk but it remains unknown. Because of this particular uncertainty, the state- ment regarding CVD was amended. Recommendations regarding peripheral vascular disease remain unchanged. 1.4.3 Assessment of frailty The role (...) to the steep LV diastolic pressure-volume relationship. 46 Because of these features, HT may be the sole therapeutic option available to improve prognosis in Mehra et al. ISHLT Listing Criteria for HT 9patients with RCM. Observations from pediatric registries show that the diagnosis of RCM is associated with worse survival and higher need for transplant than DCM or HCM. 47 In other registry series, RCM HT recipients had survival rates at 1, 5, and 10 years similar to those of non-RCM patients, except

2016 International Society for Heart and Lung Transplantation

14. Care around stillbirth and neonatal death

of the event to facilitate this process. 5 The perinatal mortality audit meetings should have an experienced chairperson capable of ensuring a no-blame environment within an appropriate legal framework. 7 Perinatal Society of Australia and New Zealand Clinical Practice Guideline for Care Around Stillbirth and Neonatal Death, Third Edition, March 2018 6 As part of the audit meeting, the PSANZ Classification system should be used to assign the cause of death and associated conditions for every perinatal (...) – RCPath Guidelines for Autopsy Investigation of Fetal and Perinatal Death Appendix P – Placental histopathology reporting form Appendix Q – Suspected genetic metabolic disorders Appendix R – Screening for genetic metabolic disorders Appendix S – Components of the genetic autopsy for investigations of metabolic disorders Appendix T – Australian and New Zealand definitions of perinatal mortality Appendix U – Changes on this version of the classifications Appendix V – Development of PSANZ Perinatal Death

2019 Publication 4891069

15. Peripheral Arterial Occlusive Disease

(C0085096) Definition (MSHCZE) Patologické procesy cév na mimosrdeční vaskulatuře. Definition (NCI) Any disorder affecting blood flow through the veins or arteries outside of the heart. Definition (CSP) condition in which there is a deviation from or interruption of the normal structure or function of the blood vessels outside the heart; diseases of the peripheral as opposed to the cardiac circulation. Definition (MSH) Pathological processes involving any one of the BLOOD VESSELS in the vasculature (...) Arterial Occlusive Disease Peripheral Arterial Occlusive Disease Aka: Peripheral Arterial Occlusive Disease , Peripheral Arterial Disease , Peripheral Vascular Disease , Arterial Insufficiency , Claudication , Vascular Claudication , Aortoilliac Occlusive Disease , Leriche's Syndrome , Iliac Artery Stenosis , Iliofemoral Occlusive Disease , Femoropopliteal Occlusive Disease , Femoropopliteal Stenosis , Femoral Arterial Stenosis , Intermittent Claudication , Acute Limb Ischemia , Critical Limb Ischemia

2018 FP Notebook

16. Diagnosis and Treatment of Peripheral Artery Diseases

of Trends and Determinants in Cardio- vascular Disease MRA magnetic resonance angiography MRI magnetic resonance imaging NASCET North American Symptomatic Carotid Endarter- ectomy Trial ONTARGET Ongoing Telmisartan Alone and in Combination with Ramipril Global Endpoint Trial OR odds ratio PAD peripheral artery diseases PARTNERS Peripheral Arterial Disease Awareness, Risk, and Treatment: New Resources for Survival PCI percutaneous coronary intervention PET positron emission tomography PRO-CAS Predictors (...) to include all vascular sites, including carotid, vertebral, upper extremity, mesenteric, renal, and lower extremity vessels. Diseases of the aorta are not covered. Although different disease processes may cause PAD, the Task Force decided to focus on atherosclerosis. Other aetiologies, speci?c for different vascular territories, are mentioned but not discussed. Atherosclerosis in the peripheral arteries is a chronic, slowly developing condition causing narrowing of the arteries. Depending on the degree

2011 European Society of Cardiology

17. Image-Guided Tumor Ablation: Standardization of Terminology and Reporting Criteria?A 10-Year Update

Image-Guided Tumor Ablation: Standardization of Terminology and Reporting Criteria?A 10-Year Update STANDARDS OF PRACTICE Image-Guided Tumor Ablation: Standardization of Terminology and Reporting Criteria—A 10-Year Update Muneeb Ahmed, MD, Luigi Solbiati, MD, Christopher L. Brace, PhD, David J. Breen, MD, Matthew R. Callstrom, MD, PhD, J. William Charboneau, MD, Min-Hua Chen, MD, Byung Ihn Choi, MD, Thierry de Baère, MD, Gerald D. Dodd, III, MD, Damian E. Dupuy, MD, Debra A. Gervais, MD, David (...) - sible electroporation (IRE), have been introduced and clinical niches are being de?ned (4). Preliminary clinical studies have matured into larger longer-term series with 5- and 10-year follow-up data on par with the surgical and medical oncology literature (5–7). Several randomized, controlled studies have been published or are under way (8,9). Over the interim, our initial document has alsogivenriseto several additional position statements within the ?eld of interven- tional oncology and been

2014 Society of Interventional Radiology

18. 2017 AHA/ACC/HRS Guideline for Management of Patients With Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death: Executive Summary: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Gui Full Text available with Trip Pro

Heart failure ACCF/AHA 2017 2016, and 2013 Valvular heart disease AHA/ACC 2017 and 2014 Supraventricular tachycardia ACC/AHA/HRS 2015 Ventricular arrhythmias and the prevention of sudden cardiac death ESC 2015 Guidelines for cardiopulmonary resuscitation and emergency cardiovascular care AHA 2015 Atrial fibrillation AHA/ACC/HRS 2014 Non–ST-elevation acute coronary syndromes AHA/ACC 2014 Assessment of cardiovascular risk ACC/AHA 2013 ST-elevation myocardial infarction ACCF/AHA 2013 Acute myocardial (...) of sudden cardiac death AHA 2016 Optimal implantable cardioverter defibrillator programming and testing HRS/EHRA/APHRS/SOLAECE 2016 Treatment of cardiac arrest: current status and future directions: strategies to improve cardiac arrest survival IOM 2015 Eligibility and disqualification recommendations for competitive athletes with cardiovascular abnormalities ACC/AHA 2015 Ventricular arrhythmias EHRA/HRS/APHRS 2014 Arrhythmias in adult congenital heart disease PACES/HRS 2014 Implantable cardioverter

2017 American Heart Association

19. Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death: Guideline For the Management of Patients With

population, frequent PVCs, which are de?ned as the presence of at least 1 PVC on a 12-lead ECG or >30 PVCs per hour, are associated with increased cardiovascular risk and increased mortality (S2.2.2-9).Inastudyfrom Taiwan of patients without sustained VT or structural heart disease who had 24-hour Holter monitoring for clinical evaluation, multifocal PVCs were associated with increased risk of death and nonfatal cardiovascular adverse outcomes (S2.2.2-10). In the same population, nonsustained ventricular (...) to ensure they do not have underlying conditions (e.g., ischemic heart disease, left ventricular [LV] dysfunction) that warrant further treatment to reduce risk. PVC and NSVTinpatientswithcardiovasculardiseasearecommon and have been associated with adverse outcomes (S2.2.2- 12,S2.2.2-13). In CAST (Cardiac Arrhythmia Suppression Trials), treatment of patients with post-myocardial infarction (MI) who took antiarrhythmic medications (e.g., ?ecainide, encainide, moricizine) increased the risk of death

2017 American College of Cardiology

20. 2017 AHA/ACC/HRS Guideline for Management of Patients With Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Hea Full Text available with Trip Pro

, the AHA, and the HRS; and endorsed by the HFSA. 1.4. Scope of the Guideline The purpose of this AHA/ACC/HRS document is to provide a contemporary guideline for the management of adults who have VA or who are at risk for SCD, including diseases and syndromes associated with a risk of SCD from VA. This guideline supersedes the “ACC/AHA/ESC 2006 Guidelines for Management of Patients With Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death.” It also supersedes some sections of the “ACC/AHA (...) artery bypass graft surgery ACCF/AHA 2011 Hypertrophic cardiomyopathy ACCF/AHA 2011 Percutaneous coronary intervention ACCF/AHA/SCAI 2011 Secondary prevention and risk reduction therapy for patients with coronary and other atherosclerotic vascular disease AHA/ACCF 2011 Scientific Statements Wearable cardioverter-defibrillator therapy for the prevention of sudden cardiac death AHA 2016 Optimal implantable cardioverter defibrillator programming and testing HRS/EHRA/APHRS/SOLAECE 2016 Treatment

2017 American Heart Association

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