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Periodontal Bleeding

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121. Clinical efficacy of probiotic as an adjunctive therapy to non-surgical periodontal treatment of chronic periodontitis: A systematic review and meta-analysis. (PubMed)

Clinical efficacy of probiotic as an adjunctive therapy to non-surgical periodontal treatment of chronic periodontitis: A systematic review and meta-analysis. What is the clinical influence of probiotics as an adjunctive therapy of scaling and root planing (SRP) when compared with SRP alone or in combination with placebo in the treatment of chronic periodontitis (CP).Electronic databases were searched up to July 2015. Randomized controlled trials (RCTs) comparing SRP + probiotic versusSRP were (...) included. PPD reduction and CAL gain were selected as primary outcome variables.Independent screening resulted in four eligible publications for the systematic review and three were included in the meta-analysis. Meta-analysis showed a statistically significant CAL gain (-0.42 mm, p = 0.002) and bleeding on probing (BOP) reduction (-14.66, p = 0.003) for SRP + probiotic treatment versusSRP at short-term. Only a tendency (p = 0.06) has been observed in terms of overall PPD reduction, whereas results

2016 Journal of Clinical Periodontology

122. Efficacy of non-surgical periodontal therapy in the management of chronic periodontitis among obese and non-obese patients: a systematic review and meta-analysis. (PubMed)

were included. The total number of patients ranged between 30 and 260 individuals. The mean age of patients was between 42.5 and 48.8 years. In three studies, the clinical periodontal parameters (plaque index (PI), gingival bleeding index (GBI), periodontal pocket depth (PPD), and clinical attachment loss (CAL)) in obese and non-obese patients following NSPT was comparable. Meta-analysis of PPD and CAL among obese and non-obese subjects showed comparable outcomes (PPD P = 0.91, I (2) 67.36 %; CAL P (...) Efficacy of non-surgical periodontal therapy in the management of chronic periodontitis among obese and non-obese patients: a systematic review and meta-analysis. There is a controversy over the influence of obesity on the periodontal treatment outcome in patients with chronic periodontitis (CP). The aim of the present systematic review was to evaluate the efficacy of non-surgical periodontal therapy (NSPT) in the management of CP among obese and non-obese patients.The addressed focused

2016 Clinical oral investigations

123. Clinical Efficacy of Azithromycin as an Adjunctive Therapy to Non-Surgical Periodontal Treatment of Periodontitis: A Systematic Review and Meta-Analysis. (PubMed)

Clinical Efficacy of Azithromycin as an Adjunctive Therapy to Non-Surgical Periodontal Treatment of Periodontitis: A Systematic Review and Meta-Analysis. Over the years, numerous trials have sufficiently documented benefits of adjuvant administration of antibiotics in combination to Scaling and Root Planing (SRP) in treatment of periodontitis. Nevertheless there are justified doubts in respect to antibiotics administration with regard to increasing development of resistances.The aim (...) of this review study and meta-analysis was to verify a possible benefit of Azithromycin (AZM) as an alternative adjuvant antibiotic in combination with SRP.Electronic databases (Pubmed) were searched from the earliest point of record until May 2015. A hand search was also conducted. The variables considered in this respect were Probing Depth (PD), Clinical Attachment Level (CAL), Bleeding on Probing (BOP) and SRP. A meta-analysis containing trials comparing SRP as a sole therapy with SRP and administration

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2016 Journal of clinical and diagnostic research : JCDR

124. Full mouth periodontal debridement with or without adjunctive metronidazole gel in smoking patients with chronic periodontitis: A pilot study. (PubMed)

) + periodontal debridement; and (iii) a daily single dose of 750 mg Mtz (Flagyl(®)) + periodontal debridement. Clinical parameters (visible plaque index, gingival bleeding index [GBI], relative attachment level and PPD) and quantitative analysis (by real-time polymerase chain reaction) of Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis and Tannerella forsythia were assessed at baseline and at 1, 3 and 6 mo after periodontal debridement.There was no statistically significant difference (...) Full mouth periodontal debridement with or without adjunctive metronidazole gel in smoking patients with chronic periodontitis: A pilot study. The evidence of effectiveness of metronidazole (Mtz) as an adjunct therapy to periodontal procedure in the treatment of patients with chronic periodontitis is not conclusive. The aim of this study was to compare the effect of Mtz (delivered locally as a gel or systemically as a tablet) as an adjunctive therapy with full mouth periodontal debridement (1 h

2016 Journal of periodontal research

125. Predictors of clinical outcomes after periodontal treatment of aggressive periodontitis: 12-month randomized trial. (PubMed)

Predictors of clinical outcomes after periodontal treatment of aggressive periodontitis: 12-month randomized trial. Little is known about the factors that may be used in clinical practice to predict the therapeutic response of aggressive periodontitis patients. The aim of this study was to determine predictors of clinical outcomes after non-surgical treatment of aggressive periodontitis. A total of 24 patients (aged 13-26 years) received oral hygiene instructions, as well as subgingival scaling (...) and root planing. Twelve subjects received systemic azithromycin at random. Clinical variables were assessed at baseline, 3, 6, 9, and 12 months. Baseline microbiological assessment was performed by checkerboard DNA-DNA hybridization. Multivariable models used generalized estimating equations. There were significant improvements in the entire sample in regard to pocket depth, clinical attachment level and bleeding on probing. Significant predictors of a reduction in mean pocket depth were: use

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2016 Brazilian oral research

126. Green Tea Intake as an Adjunct to Mechanical Periodontal Therapy for the Management of Mild to Moderate Chronic Periodontitis: A Randomized Controlled Clinical Trial. (PubMed)

Green Tea Intake as an Adjunct to Mechanical Periodontal Therapy for the Management of Mild to Moderate Chronic Periodontitis: A Randomized Controlled Clinical Trial. To evaluate and compare the beneficial effects of green tea intake on the total antioxidant capacity of gingival crevicular fluid (GCF) and plasma, and to examine its role as an adjunct to nonsurgical periodontal therapy for the management of chronic periodontitis.120 subjects with mild to moderate chronic periodontitis were (...) divided equally into two groups. After scaling and root planing in all subjects, green tea supplements were given to the case group and a placebo to the control group. The clinical parameters gingival index, plaque index, clinical probing depth, clinical attachment loss, percentage of sites with bleeding on probing, along with total antioxidant capacity of GCF and plasma were recorded at baseline, one and three months.There was a significant improvement in all clinical parameters along with an 8-fold

2016 Oral health & preventive dentistry

127. Influence of Type 2 Diabetes on Prevalence of Key Periodontal Pathogens, Salivary Matrix Metalloproteinases, and Bone Remodeling Markers in Sudanese Adults with and without Chronic Periodontitis (PubMed)

and chronic periodontitis (DM + CP), 29 with chronic periodontitis (CP), and 20 with type 2 diabetes (DM). Questionnaire-guided interviews were conducted and plaque index, bleeding on probing, and pocket depth were recorded. Polymerase chain reaction (PCR) was utilized to determine the prevalence of the bacteria. The levels of salivary molecules were determined by enzyme immunosorbent assay (ELISA). The CP group had the highest prevalence of P. gingivalis (81.5%), followed by the DM + CP (59.3%) and DM (...) Influence of Type 2 Diabetes on Prevalence of Key Periodontal Pathogens, Salivary Matrix Metalloproteinases, and Bone Remodeling Markers in Sudanese Adults with and without Chronic Periodontitis This study compared the influence of type 2 diabetes on the occurrence of six periodontal pathogens in plaque samples of patients with and without chronic periodontitis. Levels of salivary MMP-8, MMP-9, RANKL, and OPG were also investigated. The study enrolled 31 patients with type 2 diabetes

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2016 International journal of dentistry

128. Effects of Omega-3 Plus Low-dose Aspirin as Adjunct to Periodontal Debridement for Chronic Periodontitis in Diabetics

) [ Time Frame: Baseline, 90 days, 180 days ] Using a manual periodontal probe (North Carolina, HuFriedy, Chicago, IL, USA) Gingival recession (mm) [ Time Frame: Baseline, 90 days, 180 days ] Using a manual periodontal probe (North Carolina, HuFriedy, Chicago, IL, USA) Bleeding on probing (%) [ Time Frame: Baseline, 90 days, 180 days ] Using a manual periodontal probe (North Carolina, HuFriedy, Chicago, IL, USA) Plaque index (%) [ Time Frame: Baseline, 90 days, 180 days ] Using a manual periodontal (...) Effects of Omega-3 Plus Low-dose Aspirin as Adjunct to Periodontal Debridement for Chronic Periodontitis in Diabetics Effects of Omega-3 Plus Low-dose Aspirin as Adjunct to Periodontal Debridement for Chronic Periodontitis in Diabetics - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number

2016 Clinical Trials

129. A new screening method for periodontitis: an alternative to the community periodontal index. (PubMed)

or absence of calculus, bleeding on probing and pocket depth were recorded. In this study, periodontitis was defined according to the criteria of the Center for Disease Control and Prevention in partnership with the American Academy of Periodontology. In order to examine hemoglobin and lactate dehydrogenase levels in saliva, participants were instructed to chew on a standard-sized tasteless and odorless gum base for 5 min, during which time, stimulated whole saliva was continuously collected.The (...) A new screening method for periodontitis: an alternative to the community periodontal index. Periodontal screening plays an important role in the prevention of periodontal disease and promotes an improvement in oral health-related quality of life. The World Health Organization's Community Periodontal Index should be carried out by well-trained dentists. However, the Community Periodontal Index is an invasive technique, and if used for periodontal screening, increases the cost of evaluation

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2016 BMC Oral Health

130. Non-surgical periodontal treatment in conjunction with 3 or 7 days systemic administration of Amoxicillin and Metronidazole in severe chronic periodontitis patients. A placebo controlled randomized clinical study. (PubMed)

Non-surgical periodontal treatment in conjunction with 3 or 7 days systemic administration of Amoxicillin and Metronidazole in severe chronic periodontitis patients. A placebo controlled randomized clinical study. To evaluate the effect of 3 or 7 days systemic administration of amoxicillin (AMX) and metronidazole (MET) or placebo as adjunct to non-surgical periodontal treatment in severe chronic periodontitis patients.One hundred and two patients with severe chronic periodontitis [e.g. ≥1 site (...) with probing pocket depth (PD) ≥ 6 mm per quadrant] were randomly divided into three equally sized groups and treated with either scaling and root planing within 24 h (SRP) + placebo (Group A) or SRP + AMX + MET (both 500 mg × 3 times daily) for 3 days (Group B) or SRP + AMX + MET (both 500 mg × 3 times daily) for 7 days (Group C). PD, clinical attachment level (CAL), bleeding on probing (BOP), full-mouth plaque scores (FMPS) and gingival bleeding index (GBI) were assessed prior to treatment (baseline

2016 Journal of Clinical Periodontology

131. Interdental brushing for the prevention and control of periodontal diseases and dental caries in adults. (PubMed)

Interdental brushing for the prevention and control of periodontal diseases and dental caries in adults. Effective oral hygiene is a crucial factor in maintaining good oral health, which is associated with overall health and health-related quality of life. Dental floss has been used for many years in conjunction with toothbrushing for removing dental plaque in between teeth, however, interdental brushes have been developed which many people find easier to use than floss, providing (...) there is sufficient space between the teeth.To evaluate the effects of interdental brushing in addition to toothbrushing, as compared with toothbrushing alone or toothbrushing and flossing for the prevention and control of periodontal diseases, dental plaque and dental caries.We searched the following electronic databases: the Cochrane Oral Health Group's Trials Register (to 7 March 2013), the Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library 2013, Issue 2), MEDLINE via OVID (1946

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2013 Cochrane

132. Routine scale and polish for periodontal health in adults. (PubMed)

Routine scale and polish for periodontal health in adults. Many dentists or hygienists provide scaling and polishing for patients at regular intervals, even if those patients are considered to be at low risk of developing periodontal disease. There is debate over the clinical effectiveness and cost effectiveness of 'routine scaling and polishing' and the 'optimal' frequency at which it should be provided for healthy adults.A 'routine scale and polish' treatment is defined as scaling (...) or polishing or both of the crown and root surfaces of teeth to remove local irritational factors (plaque, calculus, debris and staining), that does not involve periodontal surgery or any form of adjunctive periodontal therapy such as the use of chemotherapeutic agents or root planing.The objectives were: 1) to determine the beneficial and harmful effects of routine scaling and polishing for periodontal health; 2) to determine the beneficial and harmful effects of providing routine scaling and polishing

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2013 Cochrane

133. Gingivitis and periodontitis

Gingivitis and periodontitis Gingivitis and periodontitis - NICE CKS Clinical Knowledge Summaries Share Gingivitis and periodontitis: Summary Gingivitis is inflammation of the gums. Acute necrotizing ulcerative gingivitis (ANUG) is an acute, atypical, progressive, and painful bacterial infection of the gums with ulceration and necrosis of the dental papillae and bleeding. Periodontitis is chronic inflammation involving the supporting tissues around the teeth with largely irreversible tissue (...) . Detachment of the gum from the tooth with the formation of periodontal pockets. Loss of multiple teeth. In gingivitis, discomfort from gums is rare; other features include: Reddening and swelling of the gum margins. Bleeding of gums with tooth brushing, flossing, or gentle probing. In periodontitis, symptoms (including pain) are commonly absent, but some people have: Halitosis. Foul taste in the mouth. Recession and associated root sensitivity. Drifting/loosening of teeth causing difficulty in eating

2017 NICE Clinical Knowledge Summaries

134. Correlation of serum cytokines, chemokines, growth factors and enzymes with periodontal disease parameters. (PubMed)

in association with periodontal conditions in PD and RA subjects.Periodontal examination was performed in RA (n = 38), PD (n = 38) and healthy subjects (n = 14). Bleeding on probing (BOP) and probing pocket depth (PPD) were measured. Marginal bone loss (MBL) for premolars and molars was measured on digital panoramic radiographs. PD was defined as present if the PPD was ≥5mm in ≥ 3 different sites. Serum samples were collected from all subjects. A multiplex proximity extension assay (PEA) was used to analyze (...) Correlation of serum cytokines, chemokines, growth factors and enzymes with periodontal disease parameters. Periodontal disease (PD) is characterized by inflammatory tissue destruction in tooth supporting apparatus. Many studies indicate that the underlying pathogenesis is in concordance with rheumatoid arthritis (RA) sharing immune-inflammatory events affect both diseases. The aim of this study was to investigate serum cytokines, chemokines, growth factors, enzymes and costimulatory proteins

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2017 PLoS ONE

135. Probiotics – insufficient evidence supporting use to manage caries or periodontal disease

; 0.15 – 0.52). For periodontal pathogens, no significant difference was found. Probiotics significantly reduced bleeding-on-probing (SMD: -1.15; -1.68 to -0.62) and gingival index (SMD: -0.86; -1.52 to-0.20), but not plaque index (SMD: -0.34; -0.89 to 0.21). Probing-pocket depths (SMD: -0.86; -1.55 to -0.17) were significantly reduced. Data was quantitatively insufficient for conclusive findings; overall the evidence supporting probiotic therapy was graded as very low for all outcomes 25 studies (...) Probiotics – insufficient evidence supporting use to manage caries or periodontal disease Probiotics- insufficient evidence for use in caries management Search National Elf Service Search National Elf Service » » » » Probiotics – insufficient evidence supporting use to manage caries or periodontal disease Apr 18 2016 Posted by The potential for probiotic species to have a beneficial effect on cariogenic or periodontal pathogens has been demonstrated in vitro studies and a number of clinical

2016 The Dental Elf

136. Salivary biomarkers for diagnosing periodontal disease

Salivary biomarkers for diagnosing periodontal disease Salivary biomarkers for diagnosing periodontal disease Search National Elf Service Search National Elf Service » » » » Salivary biomarkers for diagnosing periodontal disease May 6 2016 Posted by Diagnosis of periodontal disease usually consists of measuring clinical parameters such as pocket probing depth (PPD), clinical attachment levels (CALs), bleeding on probing, and radiography to assess alveolar bone level. Mediators of tissue (...) destruction can be found in the saliva of patients with periodontal disease and the potential to use these biomarkers as a non-invasive of identifying patients with disease and monitoring the progress of treatment has been proposed. The aim of this review was to evaluate the diagnostic value of salivary biomarkers in periodontal disease, in order to determine which of the numerous biomarkers reported in literature have an excellent or acceptable diagnostic test accuracy (DTA), and to provide insights

2016 The Dental Elf

137. Periodontal disease and quality of life

Periodontal disease and quality of life Periodontal disease and quality of life - National Elf Service Search National Elf Service Search National Elf Service » » » » Periodontal disease and quality of life Apr 25 2016 Posted by Periodontal diseases (PDs) are very common worldwide and are associated with a range of systemic disease e.g atherosclerotic cardiovascular, and rheumatoid diseases. As patients often live with no or few symptoms (bleeding, swelling tooth mobility) they are often (...) considered to be ‘silent diseases’. The aim of this review was to investigate associations between clinically measured PDs (gingivitis and periodontitis) and impairment of Oral Health-Related Quality of Life (OHRQoL), and to analyse a potential influence of disease severity on the degree of perceived impairment. Methods Searches were conducted in Medline, Embase and the OpenGrey databases supplemented by hand searches in the Journal of Clinical Periodontology, Journal of Periodontology Original studies

2016 The Dental Elf

138. Lasers for surgical periodontal treatment – insufficient evidence of effectiveness

Lasers for surgical periodontal treatment – insufficient evidence of effectiveness Lasers for surgical periodontal treatment – insufficient evidence of effectiveness - National Elf Service Search National Elf Service Search National Elf Service » » » » Lasers for surgical periodontal treatment – insufficient evidence of effectiveness Mar 22 2016 Posted by Studies and reviews have suggests a possible benefits with the use of lasers as an adjunct to periodontal treatment. The aim of this review (...) was to evaluate and compare various lasers as monotherapy or adjunctive to surgical periodontal therapy. Methods Searches were conducted in the Cochrane Central Register of Controlled Trials (CENTRAL), Cochrane Oral Health Group Trials Register, Medline and Embase databases. Prospective or retrospective, randomized or not, cohort or case series involving human patients in which outcomes of surgical periodontal therapy using lasers were compared with other surgical approaches were considered Two independent

2016 The Dental Elf

139. Chronic periodontitis – probiotics as a adjunct to treatment?

. This includes 12 RCTs and the abstract reports that in general, oral administration of probiotics improved the recognized clinical signs of chronic and aggressive periodontitis such as probing pocket depth, bleeding on probing, and attachment loss, with a concomitant reduction in the levels of major periodontal pathogens’ However, I have not been able to access the full review and overall the number of studies available is small and mainly of short duration so larger studies of longer duration a needed (...) Chronic periodontitis – probiotics as a adjunct to treatment? Chronic periodontitis –probiotics as a adjunct to treatment? Search National Elf Service Search National Elf Service » » » » Chronic periodontitis – probiotics as a adjunct to treatment? May 31 2016 Posted by Oral hygiene instruction and scaling and root planing (SRP) is the mainstay of care for the management of chronic periodontal disease (CP) . The use of probiotics to modulate oral biofilms has been suggested as an adjunct to SRP

2016 The Dental Elf

140. Impacted canines – insufficient evidence for best surgical approach for good periodontal outcomes

studies (1 controlled trial, 2 retrospective cohorts) involving a total of 94 patients were included No included study examined the periodontal outcome of the closed eruption technique. Excisional uncovering was reported to have a detrimental effect on the periodontium (bleeding of the gingival margin, 29% vs 7% in the control group; gingival recession, -0.5 mm [SD, 1.0] vs -1.5 mm [SD, 0.8] in the control group; and width of keratinized gingiva, 2.6 mm [SD, 1.4] vs 4.1 mm [SD, 1.5] in the control (...) Impacted canines – insufficient evidence for best surgical approach for good periodontal outcomes Impacted canines–insufficient evidence for best surgical approach Search National Elf Service Search National Elf Service » » » » Impacted canines – insufficient evidence for best surgical approach for good periodontal outcomes Jun 6 2016 Posted by Around 4% of patients referred to orthodontists have impacted canines and about one third of these canines are impacted labially. Once sufficient space

2016 The Dental Elf

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