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Periodontal Bleeding

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61. Efficacy of combined orthodontic-periodontic treatment for patients with periodontitis and its effect on inflammatory cytokines: A comparative study. (PubMed)

) and the combined group (receiving combined orthodontic-periodontic treatment, n = 59). In addition, 52 healthy people without periodontal disease were selected as the normal group. Probing depth, tooth mobility, plaque index, clinical attachment level, and sulcus bleeding index were recorded. ELISA was applied to detect gingival crevicular fluid (GCF) and serum levels of inflammatory cytokines. A 2-year clinical follow-up was conducted.Before treatment, the periodontal parameters (probing depth, tooth mobility (...) , plaque index, clinical attachement level, and sulcus bleeding index) and GCF and serum levels of inflammatory cytokines (high-sensitivity C-reactive protein, interleukin-1β, interleukin-5, interleukin-6, interleukin-8, tumor necrosis factor-α, and prostaglandin E2) in the combined and basic groups were higher than those in the normal group. After 6 and 18 months of treatment, the periodontal parameters and GCF and serum levels of inflammatory cytokines decreased in the combined and basic groups

2017 American journal of orthodontics and dentofacial orthopedics

62. Effects of periodontal endoscopy on the treatment of periodontitis: A systematic review and meta-analysis. (PubMed)

periodontal endoscopy that were published through January 2017. The authors considered the percentage of residual calculus, average treatment time, bleeding on probing (BOP), gingival inflammation (GI), and probing depth (PD) as outcome measures. The authors extracted data and performed meta-analyses for groups of articles for which it was appropriate.The authors identified 8 articles as being suitable for this systematic review. The investigators of 3 studies reported results related to BOP and GI (...) Effects of periodontal endoscopy on the treatment of periodontitis: A systematic review and meta-analysis. For this systematic review, the authors evaluated and synthesized the available scientific evidence related to the effects of periodontal endoscopy on the treatment of periodontitis.The authors searched PubMed, Embase, Cochrane Library, Chinese Scientific Journals database, China National Knowledge Infrastructure, and Chinese Medicine Premier's Wanfang database for articles about

2017 Journal of the American Dental Association (1939)

63. Effect of nonsurgical periodontal treatment on clinical periodontal variables and salivary resistin levels in obese Asians. (PubMed)

Effect of nonsurgical periodontal treatment on clinical periodontal variables and salivary resistin levels in obese Asians. This study investigated changes in periodontal outcomes after nonsurgical periodontal treatment (NSPT) and evaluated associations of change in salivary resistin level with periodontal outcomes in obese Malaysians with chronic periodontitis. Sixty-two obese adults with chronic periodontitis were randomly divided into a test group (n = 31), which received NSPT, and a control (...) group (n = 31), which received no treatment. Plaque score (PS), gingival bleeding index (GBI), probing pocket depth (PPD), and clinical attachment loss (CAL) were measured at baseline and at 6 and 12 weeks after NSPT. Salivary resistin levels were evaluated by using an enzyme-linked immunosorbent assay. PS was significantly lower in patients who received NSPT than in the control group at 6 and 12 weeks (P < 0.05). In the NSPT group the percentages of sites with shallow and moderate pockets decreased

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2017 Journal of oral science

64. Periodontal inflamed surface area as a novel numerical variable describing periodontal conditions (PubMed)

Periodontal inflamed surface area as a novel numerical variable describing periodontal conditions A novel index, the periodontal inflamed surface area (PISA), represents the sum of the periodontal pocket depth of bleeding on probing (BOP)-positive sites. In the present study, we evaluated correlations between PISA and periodontal classifications, and examined PISA as an index integrating the discrete conventional periodontal indexes.This study was a cross-sectional subgroup analysis of data (...) <0.01, respectively; Pearson correlation test). Porphyromonas gingivalis (P. gingivalis) expression and the presence of serum P. gingivalis antibodies were significant factors affecting PISA values in a simple linear regression analysis, together with periodontal classification, PI, bleeding index, and smoking, but not in the multivariate analysis. In the multivariate linear regression analysis, PISA values were positively correlated with the quantity of current smoking, PI, and severity

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2017 Journal of periodontal & implant science

65. Kiwifruit Effect on Periodontal Inflammation Kiwifruit Effect on Periodontal Inflammation

examined and included in the study. After 2 months subjects also received non-surgical periodontal treatment and then followed for additional 3 months. Subjects in the control group didi not receive any dietary advice. Procedure: Non Surgical periodontal treatment Non-surgical treatment of periodontal pockets with hand and ultrasonic instrumentation Outcome Measures Go to Primary Outcome Measures : Full-mouth bleeding score (FMBS) [ Time Frame: Baseline, 2 months and 3 months after periodontal (...) Inclusion Criteria: proximal attachment loss of ≥3 mm in ≥2 non-adjacent teeth, PPD≥4 mm and bleeding on probing on at least 25 % of their total sites documented radiographic bone loss Exclusion Criteria: younger than 18 years or older than 70 years, pregnant or lactating females, females using contraceptive pharmacological medications, reported diagnosis of any systemic illnesses including cardiovascular, renal, and liver diseases, in need of antibiotic treatment during initial periodontal treatment

2017 Clinical Trials

66. Periodontal Debridement Associated With Systemic Antibiotics and Single/Repeated PDT to Treat Aggressive Periodontitis

≥5 mm with bleeding on probing and ≥2 sites with PD ≥7 mm (including incisors and first molars, in addition to two other non-contiguous teeth between them); presence of three non-adjacent periodontal pockets with probing depth ≥5 mm and bleeding on probing not located in furcation area; good general health (ASA I/II); 18-35 years old; agree to participate in the study and sign a written consent (Resolution # 196 of October 1996 and the Brazilian Professional Code of Dental Ethics - 179/93 (...) Periodontal Debridement Associated With Systemic Antibiotics and Single/Repeated PDT to Treat Aggressive Periodontitis Periodontal Debridement Associated With Systemic Antibiotics and Single/Repeated PDT to Treat Aggressive Periodontitis - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum

2017 Clinical Trials

67. The Effect of Nonsurgical Periodontal Therapy on HNP1-3 Level in Gingival Crevicular Fluid of Chronic Periodontitis Patients (PubMed)

after it, clinical periodontal parameters were measured and GCF was collected from previously chosen site. The level of HNP1-3 in GCF was determined by means of a commercially available enzyme-linked immunoassay kit. The periodontal therapy caused a statistically significant (p < 0.001) decrease in all the assessed clinical parameters at the sites of sample collection except for bleeding on probing. The level of HNP1-3 per measure point showed a statistically significant increase (baseline-3 months (...) The Effect of Nonsurgical Periodontal Therapy on HNP1-3 Level in Gingival Crevicular Fluid of Chronic Periodontitis Patients The rich bacterial flora of oral cavity is controlled by innate immune response, including antibacterial peptides and among them human neutrophil peptides 1-3 (HNP1-3). The knowledge of the involvement of HNPs in innate and acquired immunity of the periodontium is fragmentary. The aim of the study was to assess alterations in HNP1-3 levels in the gingival crevicular fluid

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2017 Archivum Immunologiae et Therapiae Experimentalis

68. The risk reduction of recurrent periodontal pathogens of local application minocycline HCl 2% gel, used as an adjunct to scaling and root planing for chronic periodontitis treatment (PubMed)

periodontal destruction such as loss of attachment and bone destruction occurred.A total of 81 subjects with moderate to severe periodontitis whose baseline clinical attachment loss (CAL) was ≥4 mm were randomly assigned to receive SRP alone (control group, N=39) or SRP followed by four times of local application of minocycline HCl gel (Periocline) once a week (test group, N=42). Pocket depth, CAL, and papilla bleeding index were examined at baseline, 21 days, 2, 3, and 6 months. Subgingival plaque (...) The risk reduction of recurrent periodontal pathogens of local application minocycline HCl 2% gel, used as an adjunct to scaling and root planing for chronic periodontitis treatment The aim of this study was to evaluate the clinical and microbiological effects of local application minocycline HCl 2% gel, used as an adjunct to scaling and root planing (SRP) for treatment of chronic periodontitis (CP). CP is an inflammation of periodontal tissue that is caused mainly by bacterial infection, where

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2017 Therapeutics and clinical risk management

69. Effect of initial periodontal therapy on gingival crevicular fluid cytokine profile in subjects with chronic periodontitis (PubMed)

fluid (GCF) discriminated periodontally diseased sites from healthy ones, or periodontally diseased persons from healthy ones, and assessed the impact of nonsurgical periodontal therapy on these readings. This study included 20 periodontally healthy persons (H) and 24 patients with chronic periodontitis (P). In every participant, we measured the plaque index, gingival index, probing pocket depth (PD), bleeding on probing, and recession at six sites of every tooth. GCF was collected with Durapore® (...) -csf, gm-csf, ifn-γ, mip-1β, vegf, and tnf-α) were assessed using the Bio-Plex suspension array system. Mean plaque index, gingival index, bleeding on probing, PD, and recession were significantly different between groups H and P. Differences between PP and PH sites were not significant for any of the cytokines. Il-1ra, il-6, il-17, b-fgf, gm-csf, mip-1β, and tnf-α differed significantly between HH sites and both PH and PP sites, whereas il-8 was significantly higher only at PP sites. Periodontal

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2017 Clinical and Experimental Dental Research

70. Evaluation of Efficacy of Surgical Periodontal Therapy with the Use of Bone Graft in the Treatment of Periodontal Intrabony Defects (PubMed)

replacement material in the treatment of deep intrabony pockets, compared to surgical treatment (flap surgery) without the use of bone replacement in advanced periodontitis.The study included 50 patients of both sexes with advanced periodontitis, divided into two groups. After initial periodontal therapy was performed, plaque index (PI), papillary bleeding index (PBI) were verified, and depth of periodontal pockets was measured in both groups. One group (group 1) of the patients underwent surgical therapy (...) Evaluation of Efficacy of Surgical Periodontal Therapy with the Use of Bone Graft in the Treatment of Periodontal Intrabony Defects One of the most important goals of periodontitis therapy is the elimination of deep periodontal pockets. In regenerative periodontal therapy, different types of bone grafts, membranes, growth factors, etc. are used to improve regeneration of lost periodontal tissue. The aim of this study was to evaluate the effect of surgical therapy supported by the use of bone

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2017 Medical Archives

71. Periodontal and glycemic effects of nonsurgical periodontal therapy in patients with type 2 diabetes stratified by baseline HbA1c. (PubMed)

periodontal therapy was compared among diabetic patients with good glycemic control, those with poor glycemic control, and 25 nondiabetic individuals. Periodontal and metabolic status was recorded at baseline, 3 months, and 6 months. In patients receiving treatment, periodontal parameters significantly improved and HbA1c decreased by 10.8%. Improvements in gingival index and bleeding on probing were greater in the nondiabetic participants and the treated patients with good glycemic control than (...) Periodontal and glycemic effects of nonsurgical periodontal therapy in patients with type 2 diabetes stratified by baseline HbA1c. We evaluated the effects of nonsurgical periodontal therapy in 100 patients with type 2 diabetes and chronic periodontitis. The participants were classified as having good (n = 48) or poor (n = 52) glycemic control and were further randomly allocated to receive either scaling and root planning treatment group or no treatment (n = 50 each). The effect of nonsurgical

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2017 Journal of oral science

72. The Association between Periodontal Status, Serum Lipid Levels, Lipoprotein Associated Phosholipase A2 (Lp-PLA2) in Chronic Periodontitis Subjects and Healthy Controls (PubMed)

cell apoptosis, inflammatory cell chemotaxis and endothelial cell dysfunction in CVD. Owing to its role in inflammation, it may influence the development and progression of periodontitis as well.To compare the demographic variables, Gingival Index(GI), Bleeding On Probing (BOP), Probing Pocket Depth (PPD), and Clinical Attachment Level (CAL) with serum lipid profile and Lp-PLA2 level in Chronic Periodontitis (CP) subjects.A total of 75 subjects were selected and divided into three groups; based (...) The Association between Periodontal Status, Serum Lipid Levels, Lipoprotein Associated Phosholipase A2 (Lp-PLA2) in Chronic Periodontitis Subjects and Healthy Controls Lipoprotein associated phospholipase A2 (Lp-PLA2) has been explored as a potential biomarker for Cardiovascular Disease (CVD). The human Lp-PLA2 is a serine-dependent, Ca2+- independent enzyme. It gives way to oxidised free fatty acids and lysophosphatidyl choline by hydrolysing oxidised phospholipids, that leads to smooth muscle

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2017 Journal of clinical and diagnostic research : JCDR

73. Impact of green tea intake on clinical improvement in chronic periodontitis: A randomized clinical trial. (PubMed)

Impact of green tea intake on clinical improvement in chronic periodontitis: A randomized clinical trial. To investigate the effects of daily consuming of green tea on clinical criteria in Periodontitis.Thirty patients with chronic periodontitis were randomly divided into control and experimental groups after scaling and root planning (SRP). Experimental group consumed green tea herbal for 6 weeks and the control group received no intervention. Clinical indices were measured before and 6 weeks (...) after the intervention, and compared for each groups by non-parametric Wilcoxon test and between two groups by Man-Witheny test. Significance level of the test was considered at 95%.The results showed that probing depth (PD) and bleeding index (BI) reduced significantly in both groups before and after SRP, this reduction in the intervention group was higher than the control group (P=0.003 and 0.031, respectively). On the other hand, reducing the amount of plaque index (PI) despite being significant

2018 Journal of stomatology, oral and maxillofacial surgery

74. Phytotherapy as an adjunct to nonsurgical periodontal treatment?

Phytotherapy as an adjunct to nonsurgical periodontal treatment? Phytotherapy as an adjunct to nonsurgical periodontal treatment? - National Elf Service Search National Elf Service Search National Elf Service » » » » Phytotherapy as an adjunct to nonsurgical periodontal treatment? Feb 7 2018 Posted by A range of adjuncts have been used to improve outcomes from nonsurgical periodontal treatment. These include low level lasers, antibiotics and non-steroidal anti-inflammatory drugs. Phytotherapy (...) agents are derived from plants with therapeutic effects (antimicrobial, antiseptics, anti-inflammatory etc.) and many have been approved by the US Food and Drug Administration. The aim of this review was to assess the effectiveness of local phytotherapeutics as an adjunct to scaling and root planing (SRP) Methods Searches were conducted in the Medline, Google Scholar and LILACS databases. Randomised controlled trials (RCTs) conducted in patients with chronic periodontitis receiving SRP alone versus

2018 The Dental Elf

75. Periodontal health: no additional benefit from 6 monthly Scale and Polish

Periodontal health: no additional benefit from 6 monthly Scale and Polish Periodontal health: no additional benefit from 6 monthly Scale and Polish - National Elf Service Search National Elf Service Search National Elf Service » » » » Periodontal health: no additional benefit from 6 monthly Scale and Polish Jul 16 2018 Posted by Periodontal disease is one of the most common non-communicable diseases and is a major cause of poor oral health and an important cause of tooth loss in older adults (...) . Effective plaque control by the individual is a cornerstone of successful prevention and management of periodontal disease however there is no agreed published content of oral hygiene advice (OHA) to encourage effective self-care or evidence to inform different types of OHA that could be delivered in a dental practice setting. Periodontal instrumentation (PI) or ‘scale and polish’ removes plaque and calculus to facilitate oral hygiene. However, the evidence to support the effectiveness and optimal

2018 The Dental Elf

76. Fretibacterium sp. human oral taxon 360 is a novel biomarker for periodontitis screening in the Japanese population. (PubMed)

of uncultivable bacterial species TM7 sp. HOT 356 and Fretibacterium sp. HOT 360 were significantly higher in periodontitis group than in healthy group. Only Fretibacterium sp. HOT 360 showed a significantly positive correlation with such periodontal parameters as probing pocket depth (PPD) and bleeding on probing (BOP).These findings indicate that uncultivable bacteria Fretibacterium sp. HOT 360 can be used as a saliva-based diagnostic bacterial biomarker for periodontitis screening. (...) Fretibacterium sp. human oral taxon 360 is a novel biomarker for periodontitis screening in the Japanese population. Periodontitis is a common inflammatory disease, leading to bone destruction and tooth loss. Screening for periodontitis is important in preventing the progress of this disease. Various types of bacteria have been examined as potential screening targets, but only culturable pathogenic bacteria have been considered candidates. Recently, the various uncultivable bacteria have been

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2019 PLoS ONE

77. Local Hemostatic Measures Are Enough To Control Bleeding In Implant Patients On Oral Anticoagulation Therapy

Local Hemostatic Measures Are Enough To Control Bleeding In Implant Patients On Oral Anticoagulation Therapy UTCAT3023, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title Local Hemostatic Measures Are Enough To Control Bleeding In Implant Patients On Oral Anticoagulation Therapy Clinical Question In a patient on oral anticoagulation therapy, are local hemostatic measures enough to prevent post-procedural bleeding after (...) Series Key results Nineteen studies, which included five Randomized Clinical Trials (RCTs), eleven Controlled Clinical Trials (CCTs), and three Prospective Case Series, showed that patients on Oral Anticoagulation Therapy with vitamin K antagonist reported insignificant minor bleeding in a small number of patients in comparison to patients who stopped this medication before surgery. Local hemostatic measures were used in all studies to control post-operative bleeding with no major thromboembolic

2016 UTHSCSA Dental School CAT Library

78. Full-mouth treatment modalities (within 24 hours) for chronic periodontitis in adults. (PubMed)

Full-mouth treatment modalities (within 24 hours) for chronic periodontitis in adults. Periodontitis is chronic inflammation that causes damage to the soft tissues and bones supporting the teeth. Mild to moderate periodontitis affects up to 50% of adults. Conventional treatment is quadrant scaling and root planing. In an attempt to enhance treatment outcomes, alternative protocols for anti-infective periodontal therapy have been introduced: full-mouth scaling (FMS) and full-mouth disinfection (...) (FMD), which is scaling plus use of an antiseptic. This review updates our previous review of full-mouth treatment modalities, which was published in 2008.To evaluate the clinical effects of 1) full-mouth scaling (over 24 hours) or 2) full-mouth disinfection (over 24 hours) for the treatment of chronic periodontitis compared to conventional quadrant scaling and root planing (over a series of visits at least one week apart). A secondary objective was to evaluate whether there was a difference

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2015 Cochrane

79. Treatment of periodontal disease for glycaemic control in people with diabetes mellitus. (PubMed)

the titles and abstracts retrieved by the search, selected the included trials, extracted data from included trials and assessed included trials for risk of bias.Our primary outcome was blood glucose levels measured as glycated (glycosylated) haemoglobin assay (HbA1c).Our secondary outcomes included adverse effects, periodontal indices (bleeding on probing (BOP), clinical attachment level (CAL), gingival index (GI), plaque index (PI) and probing pocket depth (PPD)), cost implications and diabetic (...) Treatment of periodontal disease for glycaemic control in people with diabetes mellitus. Glycaemic control is a key issue in the care of people with diabetes mellitus (DM). Periodontal disease is the inflammation and destruction of the underlying supporting tissues of the teeth. Some studies have suggested a bidirectional relationship between glycaemic control and periodontal disease. This review updates the previous version published in 2010.The objective is to investigate the effect

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2015 Cochrane

80. Antifibrinolytic therapy for preventing oral bleeding in patients with haemophilia or Von Willebrand disease undergoing minor oral surgery or dental extractions. (PubMed)

, such as the severity of the haemophilia, both local and systemic patient factors (such as periodontal inflammation, vasculopathy or platelet dysfunction) and intervention-related factors (such as the type and number of teeth extracted or the dimension of the wound surface). Similar to local haemostatic measures and suturing, antifibrinolytic therapy is a cheap, safe and potentially effective treatment to prevent bleeding complications in individuals with bleeding disorders undergoing oral or dental procedures (...) Antifibrinolytic therapy for preventing oral bleeding in patients with haemophilia or Von Willebrand disease undergoing minor oral surgery or dental extractions. Minor oral surgery or dental extractions (oral or dental procedures) are widely performed and can be complicated by hazardous oral bleeding, especially in people with an inherited bleeding disorder such as haemophilia or Von Willebrand disease. The amount and severity of singular bleedings depend on disease-related factors

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2015 Cochrane

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