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Periodontal Bleeding

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21. Clinical and Microbiological Effects of the Use of Erbium: Yttrium-Aluminum-Garnet Laser on Chronic Periodontitis in Addition to Nonsurgical Periodontal Treatment: A Randomized Clinical Trial-6 Months Follow-Up. (Abstract)

. Materials and methods: Thirty-eight systematically healthy, never-smoker patients with chronic periodontitis were randomly assigned to one of two groups in a parallel design: 1-scaling and root planing (SRP) and 2-SRP + Laser (SRP + L). SRP and SRP + L administration were completed within 24 h. Clinical attachment level (CAL), probing depth (PD), plaque index (PI), and bleeding on probing (BOP) were recorded at baseline and 3 and 6 months after treatment. Subgingival plaque samples were also measured 1 (...) Clinical and Microbiological Effects of the Use of Erbium: Yttrium-Aluminum-Garnet Laser on Chronic Periodontitis in Addition to Nonsurgical Periodontal Treatment: A Randomized Clinical Trial-6 Months Follow-Up. Background and objective: The purpose of this randomized controlled clinical trial is to evaluate the efficiency of erbium-doped:yttrium-aluminum-garnet (Er:YAG) laser adjunct to nonsurgical periodontal debridement on clinical periodontal parameters and red complex periodontopathogens

2019 Photobiomodulation, photomedicine, and laser surgery Controlled trial quality: uncertain

22. Vitamin E in Combination With Aspirin Can Pose Potential Postoperative Bleeding

Vitamin E in Combination With Aspirin Can Pose Potential Postoperative Bleeding UTCAT2440, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title Vitamin E in Combination With Aspirin Can Pose Potential Postoperative Bleeding Clinical Question In a patient undergoing oral surgery, can vitamin E in combination with aspirin pose increased risk of postoperative bleeding? Clinical Bottom Line Both articles indicate the enhanced (...) anti-platelet effect of aspirin in combination with vitamin E. Best Evidence (you may view more info by clicking on the PubMed ID link) PubMed ID Author / Year Patient Group Study type (level of evidence) #1) Celestini/2002 Healthy Human (blood) taking no medication. In vitro study Key results The anti-platelet aggregation effect of acetylsalicylic acid was enhanced in presence of vitamin E, by increasing the NO(nitrous oxide) production 42 fold(P #2) Gonzalez-Correa/2005 Whole blood from healthy

2013 UTHSCSA Dental School CAT Library

23. Home use of interdental cleaning devices, in addition to toothbrushing, for preventing and controlling periodontal diseases and dental caries. Full Text available with Trip Pro

Home use of interdental cleaning devices, in addition to toothbrushing, for preventing and controlling periodontal diseases and dental caries. Dental caries (tooth decay) and periodontal diseases (gingivitis and periodontitis) affect the majority of people worldwide, and treatment costs place a significant burden on health services. Decay and gum disease can cause pain, eating and speaking difficulties, low self-esteem, and even tooth loss and the need for surgery. As dental plaque (...) comparison was rubber/elastomeric cleaning sticks versus interdental brushes (3 trials).No trials assessed interproximal caries, and most did not assess periodontitis. Gingivitis was measured by indices (most commonly, Löe-Silness, 0 to 3 scale) and by proportion of bleeding sites. Plaque was measured by indices, most often Quigley-Hein (0 to 5).comparisons against toothbrushing aloneLow-certainty evidence suggested that flossing, in addition to toothbrushing, may reduce gingivitis (measured by gingival

2019 Cochrane

24. WITHDRAWN: Interdental brushing for the prevention and control of periodontal diseases and dental caries in adults. (Abstract)

WITHDRAWN: Interdental brushing for the prevention and control of periodontal diseases and dental caries in adults. Effective oral hygiene is a crucial factor in maintaining good oral health, which is associated with overall health and health-related quality of life. Dental floss has been used for many years in conjunction with toothbrushing for removing dental plaque in between teeth, however, interdental brushes have been developed which many people find easier to use than floss, providing (...) there is sufficient space between the teeth.To evaluate the effects of interdental brushing in addition to toothbrushing, as compared with toothbrushing alone or toothbrushing and flossing for the prevention and control of periodontal diseases, dental plaque and dental caries.We searched the following electronic databases: the Cochrane Oral Health Group's Trials Register (to 7 March 2013), the Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library 2013, Issue 2), MEDLINE via OVID (1946

2019 Cochrane

25. The Use of Oral Probiotics in Adjunct to Non-surgical Periodontal Treatment Is More Effective in Treating Chronic Periodontitis Than Non-surgical Periodontal Treatment Alone

/ Year Patient Group Study type (level of evidence) #1) Martin-Cabezas/ 2016 130 patients/4 studies (100 patients/3 studies for meta-analysis) having chronic periodontitis without systemic diseases Meta-Analysis Key results With the use of oral probiotics in adjunct to NSPT, meta-analysis showed there was a statistically significant difference in clinical attachment level (CAL) gain (-0.42 mm; 95% CI −0.68, −0.16; p = .002), reduction of bleeding on probing (BOP) (-14.66; 95% CI −24.49, −4.83; p (...) The Use of Oral Probiotics in Adjunct to Non-surgical Periodontal Treatment Is More Effective in Treating Chronic Periodontitis Than Non-surgical Periodontal Treatment Alone UTCAT3096, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title The Use of Oral Probiotics in Adjunct to Non-surgical Periodontal Treatment Is More Effective in Treating Chronic Periodontitis Than Non-surgical Periodontal Treatment Alone Clinical

2016 UTHSCSA Dental School CAT Library

26. Basic Periodontal Examination (BPE)

of bone loss as a percentage of root length and visualisation of the periapical tissues • When a 6-point pocket chart is indicated it is only necessary to record sites of 4mm and above (although 6 sites per tooth should be measured) • Bleeding on probing should always be recorded in conjunction with a 6-point pocket chart (...) Basic Periodontal Examination (BPE) Scoring Codes Pockets 5.5mm (Black band disappears, indicating a pocket of 6mm or more) Furcation involvement 0 2 4 1 3 * Basic Periodontal Examination (BPE) Careful assessment of the periodontal tissues is an essential component of patient management. The BPE is a simple and rapid screening tool that is used to indicate the level of further examination needed and provide basic guidance on treatment needed. These BPE guidelines are not prescriptive

2019 British Society of Periodontology

27. Basic Periodontal Examination (BPE)

of bone loss as a percentage of root length and visualisation of the periapical tissues • When a 6-point pocket chart is indicated it is only necessary to record sites of 4mm and above (although 6 sites per tooth should be measured) • Bleeding on probing should always be recorded in conjunction with a 6-point pocket chart (...) Basic Periodontal Examination (BPE) Scoring Codes Pockets 5.5mm (Black band disappears, indicating a pocket of 6mm or more) Furcation involvement 0 2 4 1 3 * Basic Periodontal Examination (BPE) Careful assessment of the periodontal tissues is an essential component of patient management. The BPE is a simple and rapid screening tool that is used to indicate the level of further examination needed and provide basic guidance on treatment needed. These BPE guidelines are not prescriptive

2019 British Society of Periodontology

28. Intra- and Post- Operative Bleeding After Simple Dental Extraction in Direct Oral Anticoagulant Therapy

of the oral cavity, registration of periodontal indices cardiological assessment [ Time Frame: 1 week before ] registration of the Atrial Fibrillation Stroke Risk score bleeding risk assessment [ Time Frame: 1 week before ] registration of the Score for Major Bleeding Risk score intra-operative bleeding [ Time Frame: intra-operative ] a standardized cotton roll is weighted after imbibition on the post-extractive alveolus for 20 seconds Eligibility Criteria Go to Information from the National Library (...) : April 2017 Individual Participant Data (IPD) Sharing Statement: Plan to Share IPD: No Layout table for additional information Studies a U.S. FDA-regulated Drug Product: No Studies a U.S. FDA-regulated Device Product: No Keywords provided by prof. Roberto Di Lenarda, University of Trieste: direct oral anticoagulant oral anticoagulant therapy dental extraction bleeding complication atrial fibrillation deep venous thrombosis Additional relevant MeSH terms: Layout table for MeSH terms Hemorrhage

2017 Clinical Trials

29. Gingival Bleeding and Von Willebrand Disease Typ 2 and 3

-regulated Device Product: No Keywords provided by Peter Eickholz, Goethe University: periodontal disease plaque-induced gingivitis bleeding on probing von willebrand disease gingival bleeding Additional relevant MeSH terms: Layout table for MeSH terms Hemorrhage Von Willebrand Diseases Gingival Hemorrhage Pathologic Processes Blood Coagulation Disorders, Inherited Blood Coagulation Disorders Hematologic Diseases Coagulation Protein Disorders Blood Platelet Disorders Hemorrhagic Disorders Genetic (...) Description Go to Brief Summary: Von Willebrand disease (VWD) is the most common inherent bleeding disorder resulting in prolonged bleeding time. Gingival bleeding is a frequently reported symptom of VWD. However, gingival bleeding is also known as a leading symptom of plaque-induced gingivitis and untreated periodontal disease. Gingival bleeding in VWD patients may be triggered by gingival inflammation and not a genuine symptom. Thus, this study evaluates whether type 2 and 3 VWD determines an increased

2017 Clinical Trials

30. Evaluation of Bleeding on Brushing Using Neem Extract Mouthwash Versus Chlorhexidine Mouthwash

a U.S. FDA-regulated Device Product: No Keywords provided by Samar Sherif Ali Mostafa, Cairo University: bleeding on brushing Additional relevant MeSH terms: Layout table for MeSH terms Hemorrhage Gingival Hemorrhage Pathologic Processes Oral Hemorrhage Mouth Diseases Stomatognathic Diseases Gingival Diseases Periodontal Diseases Chlorhexidine Chlorhexidine gluconate Anti-Infective Agents, Local Anti-Infective Agents Disinfectants Dermatologic Agents (...) the patients according to the inclusion criteria. We will take sulcus bleeding index which is defined as an index of gingival inflammation in which bleeding is measured from four gingival units using a periodontal probe. The scoring is ranging around eight anterior teeth from 0 to 5.In this study, we will take only score 2 which is bleeding on probing, change in colour and no edema in order to reduce variability. 2%neem extract will be used to prepare mouthwash while, chlorhexidine will be used as positive

2017 Clinical Trials

31. Acute periodontal lesions (periodontal abscesses and necrotizing periodontal diseases) and endo-periodontal lesions. Full Text available with Trip Pro

an objective classification system.Although PA, NPD, and EPL occur with relatively low frequency, these lesions are of clinical relevance, because they require immediate management and might severely compromise the prognosis of the tooth.In general, the evidence available to define these three conditions was considered limited. PA and EPL are normally associated with deep periodontal pockets, bleeding on probing, suppuration, and almost invariably, with pain. EPL are also associated with endodontic (...) pathology. NPDs have three typical features: pain, bleeding, and ulceration of the gingival interdental papilla. The available data suggested that the prognosis of PA and EPL are worse in periodontitis than in nonperiodontitis patients. Lesions associated with root damage, such as fractures and perforations, had the worst prognosis. NPD progression, extent and severity mainly depended on host-related factors predisposing to these diseases.PA should be classified according to the etiological factors

2018 Journal of Clinical Periodontology

32. The effects of melatonin supplementation in adjunct with non-surgical periodontal therapy on periodontal status, serum melatonin and inflammatory markers in type 2 diabetes mellitus patients with chronic periodontitis: a double-blind, placebo-controlled t (Abstract)

-6 (IL-6), hs-C-reactive protein (hs-CRP), clinical attachment loss (CAL), pocket depth (PD), bleeding on probing (BOP) and plaque index were evaluated in all subjects pre- and post-intervention.Melatonin supplementation significantly increased the mean serum levels of melatonin after intervention. The mean changes of melatonin were significantly higher in intervention group compared with control group. IL-6 and hs-CRP levels were significantly (p = 0.008 and p = 0.017, respectively) reduced (...) The effects of melatonin supplementation in adjunct with non-surgical periodontal therapy on periodontal status, serum melatonin and inflammatory markers in type 2 diabetes mellitus patients with chronic periodontitis: a double-blind, placebo-controlled t Diabetes mellitus (DM) and periodontitis are two common chronic diseases with bidirectional relationship. Oxidative stress plays a key role in the pathogenesis of these two diseases. The aim of this study was to investigate the effects

2018 Inflammopharmacology Controlled trial quality: uncertain

33. [A clinical evaluation of periodontal treatment effect using periodontal endoscope for patients with periodontitis: a split-mouth controlled study]. (Abstract)

with (test group) or without (control group) periodontal endoscope. Changes of such clinical parameters as plaque index (PLI), bleeding index (BI), probing depth (PD) and attachment loss (AL) before and after treatments as well as the difference between test and control groups were examined and compared. Results: Both groups showed significant reductions in PD, BI and AL values at 6 weeks and 3 months after treatment (P <0.001). Only in the test group, for sites with PD≥6 mm at baseline, PD value ([4.0 (...) [A clinical evaluation of periodontal treatment effect using periodontal endoscope for patients with periodontitis: a split-mouth controlled study]. Objective: To compare the clinical effects of periodontal treatment using periodontal endoscope with that of conventional treatment method for patients with periodontitis. Methods: Eleven periodontal patients with moderate to advanced periodontal destruction were recruited and treated with scaling and root planing in a split-mouth design randomly

2018 Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology Controlled trial quality: uncertain

34. Effect of immediate periodontal surgical treatment on periodontal healing in combined endodontic–periodontal lesions with communication—A randomized clinical trial Full Text available with Trip Pro

lesions with apical communication.Forty patients were randomly allocated to two treatment protocols. Group 1(immediate periodontal surgery): OFD was performed at 21 days of initiation of ET and SRP, and Group 2(delayed periodontal surgery): OFD was performed after 3 months of initiation of ET and SRP. The primary parameters included probing pocket depth (PPD), relative attachment level (RAL) and bleeding on probing (BOP) and tooth mobility (TM).Significantly more reduction in PPD, TM and gain in RAL (...) Effect of immediate periodontal surgical treatment on periodontal healing in combined endodontic–periodontal lesions with communication—A randomized clinical trial Management of combined endodontic-periodontal lesions needs more clinical investigations. The aim of this prospective randomized clinical trial was to evaluate the effect oftime interval between the non-surgical endodontic treatment (ET) and open flap debridement (OFD) on periodontal healing in combined endodontic periodontal

2018 Journal of oral biology and craniofacial research Controlled trial quality: uncertain

35. Do we treat our patients or rather periodontal microbes with adjunctive antibiotics in periodontal therapy? A 16S rDNA microbial community analysis. Full Text available with Trip Pro

Do we treat our patients or rather periodontal microbes with adjunctive antibiotics in periodontal therapy? A 16S rDNA microbial community analysis. Empiric antibiotics are often used in combination with mechanical debridement to treat patients suffering from periodontitis and to eliminate disease-associated pathogens. Until now, only a few next generation sequencing 16S rDNA amplicon based publications with rather small sample sizes studied the effect of those interventions on the subgingival (...) microbiome. Therefore, we studied subgingival samples of 89 patients with chronic periodontitis (solely non-smokers) before and two months after therapy. Forty-seven patients received mechanical periodontal therapy only, whereas 42 patients additionally received oral administered amoxicillin plus metronidazole (500 and 400 mg, respectively; 3x/day for 7 days). Samples were sequenced with Illumina MiSeq 300 base pairs paired end technology (V3 and V4 hypervariable regions of the 16S rDNA). Inter-group

2018 PLoS ONE Controlled trial quality: uncertain

36. Periodontal Therapy on HIV Patients Undergoing HAART May Provide Slight Benefit in Periodontal Health

that received HAART therapy, and one that was therapy naive Case Control Study Key results Of the periodontal parameters that were tested (probing pocket depth, gingival recession, clinical attachment level, papilla bleeding score, periodontal screening index and index for decayed, missed, and filled teeth), only the clinical marker for inflammation (the papilla bleeding score) achieved a significant difference, being twice as high (P ˂ 0.001) in the therapy naïve group (0.58 ± 0.40 versus 1.02 ± 0.59 (...) Periodontal Therapy on HIV Patients Undergoing HAART May Provide Slight Benefit in Periodontal Health UTCAT2849, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title Periodontal Therapy on HIV Patients Undergoing HAART May Provide Slight Benefit in Periodontal Health Clinical Question In adult HIV patients undergoing HAART, are clinical outcomes (BOP, clinical attachments, and reduction in pocket depth) from periodontal

2015 UTHSCSA Dental School CAT Library

37. Photodynamic Therapy (PDT) Does Not Decrease Bacterial Load More Than Conventional Therapy in Systemically Healthy Patients with Chronic Periodontitis with No Evidence Currently Available for Diabetic Patients with Chronic Periodontitis

for diabetic patients with chronic periodontitis receiving PDT, possibly with varying concentrations of RLP068 as reflected in the medical study. Clinical outcomes should also be addressed in future studies. Applicability No harmful side effects have been documented for PDT. Some possible short term benefits in clinical outcomes such as bleeding on probing, pocket depth and clinical attachment level (see CAT # 613) are documented; however PDT has not been shown to be effective at decreasing bacterial (...) Photodynamic Therapy (PDT) Does Not Decrease Bacterial Load More Than Conventional Therapy in Systemically Healthy Patients with Chronic Periodontitis with No Evidence Currently Available for Diabetic Patients with Chronic Periodontitis UTCAT2879, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title Photodynamic Therapy (PDT) Does Not Decrease Bacterial Load More Than Conventional Therapy in Systemically Healthy Patients

2015 UTHSCSA Dental School CAT Library

38. Topical Application of Fibroblast Growth Factor-2 May Promote Periodontal Regeneration in a Patient with Periodontitis

of alveolar bone height between group P (23.92%) and group H (58.62%). However, the difference in linear increase in alveolar bone height in group P (0.95 mm) and group H (1.85 mm) was not statistically significant (p=0.132). Regarding the clinical attachment loss regained, gingival recession, keratinized gingiva, tooth mobility, and plaque index, no significant differences existed between the 4 groups. Probing depth, gingival index, and bleeding on probing prevalence all decreased with time following (...) evidence is needed to consider the use of FGF-2 as the standard of care for periodontal tissue regeneration. Applicability The evidence is applicable to patients with loss of periodontal tissues due to periodontitis. At this time, there are limited data and clinical trials involving the use of FGF-2 in periodontal regeneration. Specialty/Discipline (Periodontics) Keywords Fibroblast Growth factor-2 (FGF2), periodontitis, periodontal regeneration ID# 2886 Date of submission: 03/26/2015 E-mail rakian

2015 UTHSCSA Dental School CAT Library

39. NSAIDs and bleeding in periodontal surgery. Full Text available with Trip Pro

times of patients were recorded prior to performance of periodontal flap surgical procedures.It was found that there was increased bleeding time and increased peri-operative bleeding when ibuprofen and diclofenac sodium were taken prior to surgery and this was statistically significant. (2.5538 (T1), 1.8385 (T2) versus 1.2385 (C) minute, p= .001) (mean blood loss) and (62.0325 ± 9.0594 (T1), 51.082 ± 9.792 (T2) versus 37.4992 ± 5.99 (C) millilitre, p = .000).The findings of this study suggested (...) that pre-operative administration of ibuprofen and diclofenac sodium could increase bleeding time and peri - operative blood loss.

2014 Journal of clinical and diagnostic research : JCDR Controlled trial quality: uncertain

40. Periodontitis in Coronary Heart Disease Patients: Strong Association between Bleeding on Probing and Systemic Biomarkers. Full Text available with Trip Pro

patients with periodontitis (n = 317), aged >30 years and without other systemic illness were examined. Periodontal clinical parameters of bleeding on probing (BOP), probing depth (PD), and clinical attachment level (CAL) and systemic levels of high-sensitivity C-reactive protein (CRP), fibrinogen (FIB) and white blood cells (WBC) were noted and analyzed to identify associations through linear and stepwise multiple regression analyses.Unadjusted linear regression showed significant associations between (...) Periodontitis in Coronary Heart Disease Patients: Strong Association between Bleeding on Probing and Systemic Biomarkers. Few studies have examined the relationship of individual periodontal parameters with individual systemic biomarkers. This study assessed the possible association between specific clinical parameters of periodontitis and systemic biomarkers of coronary heart disease risk in coronary heart disease patients with periodontitis.Angiographically proven coronary heart disease

2014 Journal of Clinical Periodontology

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