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Periodontal Bleeding

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261. Periodontal Status among Elderly Inhabitants of Northern Manhattan:The WHICAP Ancillary Study of Oral Health. Full Text available with Trip Pro

Periodontal Status among Elderly Inhabitants of Northern Manhattan:The WHICAP Ancillary Study of Oral Health. We conducted a cross-sectional study of the prevalence, extent and severity of periodontitis in a tri-ethnic cohort of ≥65 year-old participants of the Washington-Heights Inwood Community Aging Project (WHICAP).1,130 individuals (57% of eligible invitees) participated in a full-mouth periodontal examination that included assessments of bleeding on probing, pocket depth and clinical (...) attachment loss (CAL) at six sites/tooth.Participants had a mean age of 75.4 years (SD 6.7), were predominantly female (66.6%) and Hispanic (44.7%), and of middle/low educational attainment (~82%). The prevalence of edentulism was 14.7%, and an average of 17.1 teeth (SD 8.0) was present among the dentate. The prevalence of moderate/severe periodontitis according to the CDC/AAP definition was 77.5%. Pockets ≥6 mm were found in 50.2% of the sample, affecting an average of 5.7% of teeth/person

2018 Journal of Clinical Periodontology

262. A Chinese family with periodontal Ehlers-Danlos Syndrome associated with missense mutation in the C1R gene. (Abstract)

A Chinese family with periodontal Ehlers-Danlos Syndrome associated with missense mutation in the C1R gene. We report a rare case of the periodontal Ehlers-Danlos syndrome (pEDS) associated with severe periodontitis and tooth loss in a Chinese family.The proband complained of gingival bleeding and mobility, which were also reported in his mother, and maternal uncle and his maternal grandmother and great-grandfather in the past. All family members underwent oral, physical, dermatological (...) , and genetic examinations.Oral manifestation of family members affected with pEDS presented severe periodontitis with multiple or total tooth loss. The proband displayed unique clinical manifestations including a characteristic facial appearance and thin, translucent skin with easily visible venous patterns on feet. Whole-exome sequencing identified missense mutation c.265T>C in C1R in all affected family members tested and frameshift mutation c.1322delG in COL3A1 in the proband alone. None

2018 Journal of Clinical Periodontology

263. Complex patterns of response to oral hygiene instructions: longitudinal evaluation of periodontal patients. Full Text available with Trip Pro

Complex patterns of response to oral hygiene instructions: longitudinal evaluation of periodontal patients. Oral hygiene instruction is an intervention widely practiced but increased knowledge about oral health does not necessarily dramatically impact oral disease prevalence in populations. We aimed to measure plaque and bleeding in periodontal patients over time to determine patterns of patient response to oral hygiene instructions.Longitudinal plaque and bleeding index data were evaluated (...) in 227 periodontal patients to determine the impact of oral hygiene instructions. Over multiple visits, we determined relative plaque accumulation and gingival bleeding for each patient. Subsequently, we grouped them in three types of oral hygiene status in response to initial instructions, using the longitudinal data over the period they were treated and followed for their periodontal needs. These patterns of oral hygiene based on the plaque and gingival bleeding indexes were evaluated based on age

2018 BMC Oral Health

264. Periodontitis in patients with cirrhosis: a cross-sectional study. Full Text available with Trip Pro

attachment level, and bleeding on probing was performed. Patients were categorized as having no-or-mild, moderate, or severe periodontitis. Predictors of severe periodontitis and the association with nutritional and systemic inflammation status were analyzed using univariable and multivariable logistic regression analyses.The large majority of patients had periodontitis, 46% of them severely and 39% moderately. Predictors of severe periodontitis included smoking (odds ratio (OR) 2.93, 95% confidence (...) Periodontitis in patients with cirrhosis: a cross-sectional study. Many patients with cirrhosis have poor oral health but little is known on periodontitis, and its clinical significance is largely unknown. This study aimed to examine the prevalence and predictors of periodontitis, and evaluate the association of periodontitis with nutritional and systemic inflammation status.145 patients with cirrhosis were consecutively enrolled. Clinical, oral examination of plaque, pocket depth, clinical

2018 BMC Oral Health

265. Periodontal condition in relation to the adherence to nutrient recommendations in daily smokers. Full Text available with Trip Pro

Periodontal condition in relation to the adherence to nutrient recommendations in daily smokers. To examine whether a healthy diet based on nutrient recommendations is associated with periodontal condition in smokers.Daily smokers from the cross-sectional Health 2000 Survey (BRIF 8901) in Finland were analysed in two age groups (30-49 and 50-79 years, n = 704 and 267) and according to the level of oral hygiene. Periodontal condition was measured as the number of sextants with gingival bleeding (...) and teeth with ≥4 mm deepened periodontal pockets. Information on nutrition was collected by a validated food frequency questionnaire and measured using the Baltic Sea Diet Score (BSDS) and the Recommended Finnish Diet Score (RFDS).In the total study population, no association between the scores and periodontal condition was observed. Among 30- to 49-year-old participants with good oral hygiene, diet scores associated inversely with the number of teeth with deepened periodontal pockets (p = .078 (BSDS

2018 Journal of Clinical Periodontology

266. A. actinomycetemcomitans serotypes associate with periodontal and coronary artery disease status. (Abstract)

serotype frequencies were as follows: serotype "c" 35.7%, "b" 28.6%, "a" 26.2%, "e" 7.1%, "d" 2.4% and "f" 0%. The subjects with a detectable serotype had less teeth and higher bleeding on probing than those with no serotype. Serotypes "b" and "c" associated with periodontal probing depths and periodontal inflammatory burden. The saliva and subgingival bacterium quantities and serum antibody levels against A. actinomycetemcomitans were highest in patients harbouring serotype "c." Serotypes "b" and "c (...) A. actinomycetemcomitans serotypes associate with periodontal and coronary artery disease status. We investigated the association between the Aggregatibacter actinomycetemcomitans serotypes, periodontal status and coronary artery disease (CAD).The study population included 497 patients who underwent coronary angiography, and clinical oral examination. Quantitative polymerase chain reaction assays were designed to identify the serotypes from saliva samples.Aggregatibacter actinomycetemcomitans

2018 Journal of Clinical Periodontology

267. Serum and salivary ferritin and Hepcidin levels in patients with chronic periodontitis and type 2 diabetes mellitus. Full Text available with Trip Pro

categorized into 4 groups based on the presence or absence of CP or T2DM. Demographics and general health parameters were recorded. Full-mouth clinical periodontal parameters including probing pocket depth, clinical attachment loss, bleeding index, and plaque index were recorded. Chemiluminescence microparticle immunoassay and enzyme-linked immunosorbent assay were used to detect ferritin and hepcidin concentrations, respectively, in serum and saliva.Serum ferritin and hepcidin levels in the CP and CP (...) Serum and salivary ferritin and Hepcidin levels in patients with chronic periodontitis and type 2 diabetes mellitus. Iron disorder and abnormal expression of hepcidin play important roles in many diseases, but it is still unclear in chronic periodontitis (CP) and type 2 diabetes mellitus (T2DM). We aimed to assess ferritin and hepcidin levels in serum and saliva of CP patients with or without T2DM.Serum and unstimulated whole saliva samples were collected from 88 participants, who were

2018 BMC Oral Health

268. Effects of Probiotic Therapy in the Treatment of Periodontitis.

Effects of Probiotic Therapy in the Treatment of Periodontitis. Effects of Probiotic Therapy in the Treatment of Periodontitis. - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Effects of Probiotic Therapy (...) in the Treatment of Periodontitis. The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT03408548 Recruitment Status : Completed First Posted : January 24, 2018 Last Update Posted : January 25, 2018 Sponsor: University of Sao Paulo Collaborator: Conselho Nacional de Desenvolvimento Científico e Tecnológico

2018 Clinical Trials

269. New Periodontitis Treatment Based on Hyaluronic Acid and Melatonin

and biocompatibility tests have been performed. A randomized clinical trial will be perform on 50 patients with moderate chronic periodontitis recruited based on eligibility criteria and informed consent signed. Mechanical debridement of the pockets by scaling and root planning will be performed prior to the adjunctive therapy. Extensive clinical examination including charting the remaining teeth, clinical attachment level (CAL), presence of dental plaque (PI), gingival index (GI), calculus (CI), bleeding (...) New Periodontitis Treatment Based on Hyaluronic Acid and Melatonin New Periodontitis Treatment Based on Hyaluronic Acid and Melatonin - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. New Periodontitis

2018 Clinical Trials

270. Regenerative Potential of Cultured Gingival Fibroblast- Mesenchymal Stem Cells in Treatment of Periodontitis

Criteria Inclusion Criteria: Presence of interproximal osseous defects estimated from radiographic evaluation (Cone Beam CT) and transgingival bone sounding ≥3mm of two or three osseous walls. Probing Depth ≥5mm after initial therapy. Attachment loss ≥4mm. full mouth plaque score and bleeding on probing score ≤ 20% after phase I therapy. non vital teeth only involved. no furcation involvement of the teeth presenting the intraosseous defects. Thick gingival biotype more than 1 mm with enough width (...) Regenerative Potential of Cultured Gingival Fibroblast- Mesenchymal Stem Cells in Treatment of Periodontitis Regenerative Potential of Cultured Gingival Fibroblast- Mesenchymal Stem Cells in Treatment of Periodontitis - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies

2018 Clinical Trials

271. The Effect of Periodontal Disease Treatment in Patients With Kidney Disease

periodontal treatment. All clinical measurements were taken from the mid-buccal and mid-lingual sites and the buccal aspects of the interproximal contact area for the mesial and distal sites of each tooth to the nearest 0.5 mm using a 15 mm periodontal probe at baseline and the 6th months after treatment. All periodontal clinical examinations were performed by one calibrated examiner (FOT). At baseline and 6 months after treatment, fasting venous blood samples were collected from the antecubital fossa (...) by an experienced nurse. Blood samples for TNF- α, IL-6 and PTX-3 were centrifuged, and separated serum and plasma samples were stored at -80◦C until analysis. TNF-α , IL-6 , and PTX-3 serum levels were determined using a commercial solid-phase enzyme-linked immunosorbent assay (ELISA) kit according to the manufacturer's instructions. Periodontal treatments were performed 2 hours after the patients had their breakfast following the blood sampling. Standard oral hygiene instructions were given to all groups

2018 Clinical Trials

272. Adjunctive Use of Salvadora Persica in Chronic Periodontitis

by one trained interviewer that will include the data regarding; (a) age; (2) gender; (3) education status; (4) occupation; (5) medical status INFORMED CONSENT: All eligible subjects will be thoroughly informed of the nature, potential risks and benefits of their participation in the study. ASSESSMENT OF PARAMETERS: CLINICAL PERIODONTAL PARAMETERS Full-mouth plaque index (PI), bleeding on probing (BOP), probing depth (PD), and clinical attachment loss (CAL) will be recorded on baseline, 6th week (...) examiner, using a UNC 15 probe and expressed in millimetres. The value will be entered into the periodontal chart provided with the questionnaire. bleeding on probing [ Time Frame: 3 months ] presence or absence of bleeding on probing within 10 seconds around 6 points along each tooth. Presence of bleeding will be marked as 1, while absence will be marked as 0. plaque index [ Time Frame: 3 months ] presence of absence of plaque along 6 points around each tooth will be examined and entered

2018 Clinical Trials

273. Periodontal disease in adults with diabetes, prevalence and risk factors. Results of an observational study. (Abstract)

Interview Surveys, conducted from 2003 to 2014 in Spain. We included 65 295 subjects ≥40 years. Diabetes status was self-reported. One non-diabetic control was matched by the year-of-survey, age and sex for each diabetic patient. The presence of periodontal disease was defined using the answer "my teeth bleed spontaneously or while brushing" or/and "my teeth move" to the following question: "Do you suffer of any of these dental and oral disorders or disease?". Independent variables included demographic (...) Periodontal disease in adults with diabetes, prevalence and risk factors. Results of an observational study. We sought (a) to assess the association between periodontal disease and diabetes, controlling for socio-demographic characteristics, comorbidities, oral health status and lifestyle variables; (b) to identify which of these variables are independently associated with periodontal disease among diabetes sufferers.We conducted a case-control study using data from the National/European Health

2018 International journal of clinical practice

274. Periodontitis affects glucoregulatory hormones in severely obese individuals. Full Text available with Trip Pro

Periodontitis affects glucoregulatory hormones in severely obese individuals. To evaluate the effect of periodontitis (PD) on glucoregulatory hormones in obesity, never explored so far, a cross-sectional study was conducted in 110 severely obese, non-diabetic individuals.We collected clinical periodontal parameters, including probing pocket depth (PPD), bleeding on probing (BOP), clinical attachment level (CAL). Insulin, glucagon, GLP-1 and GIP were measured after 3 days of standardized (...) diet.Forty-seven subjects had periodontitis (PD+) and 63 did not (PD-). PD+ showed 30.3% of gingival sites with PPD > 4 mm, 55.2% of BOP sites and a mean CAL loss of 4.1 mm. Compared with PD-, PD+ had higher glucagon (26.60 [25.22] vs 3.93 [7.50] ng/l, p < 0.0001) and GIP levels (10.56 [13.30] vs 6.43 [8.43] pmol/l, p < 0.001), while GLP-1 was reduced (11.78 [10.07] vs 23.34 [16.80] pmol/l, p < 0.0001). Insulin did not differ. In PD+, after adjustment for confounders, PPD was positively related

2018 International Journal of Obesity

275. Association between periodontal health status and patient reported outcomes in patients managed in a non-specialist, general dental practice. Full Text available with Trip Pro

), alveolar bone loss (ABL), bleeding on probing (BoP) as well as PROs (oral pain/discomfort, dietary restrictions and dental appearance) were recorded using an online database. The associations between periodontal status and PROs were investigated using logistic regression analysis, adjusting for confounders.We found a positive association between worse periodontal health and the prevalence of PROs. After adjustment for confounders, 13.8% of patients in the healthiest category (PPD < 5 mm, ABL < 2 mm (...) Association between periodontal health status and patient reported outcomes in patients managed in a non-specialist, general dental practice. To explore the associations between periodontal status and patient-reported outcomes (PROs) in a large cohort of patients based in non-specialist general dental practice.Analysis was conducted using data from 14,620 patients, in 233 non-specialist dental practices across the UK. As part of routine clinical care, data on periodontal probing depths (PPD

2018 Journal of Clinical Periodontology

276. Effects of nonsurgical periodontal treatment on glycated haemoglobin on type 2 diabetes patients (PARODIA 1 study): a randomized controlled trial in a sub-Saharan Africa population. Full Text available with Trip Pro

planning along with subgingival 10% povidone iodine irrigation, whereas the control group (Group 2, n = 17) was assigned to receive delayed periodontal treatment 3 months later. Pharmacological treatment was unchanged and all participants received the same standardized education session on diabetes management and dental hygiene. The primary outcome was the 3-month change in HbA1c from baseline. Plaque index (PI), gingival bleeding index (GBI), pocket depth (PD), clinical attachment loss (CAL) were also (...) Effects of nonsurgical periodontal treatment on glycated haemoglobin on type 2 diabetes patients (PARODIA 1 study): a randomized controlled trial in a sub-Saharan Africa population. There is a burglar association between diabetes and periodontitis. Many studies has shown that periodontitis treatment can help improving glycemic control in diabetes patients but little evidence of non-surgical treatment benefit is available in sub Saharan african diabetes patients. We aimed to assess the effects

2018 BMC Oral Health Controlled trial quality: predicted high

277. Using Evidence-Based Dentistry in the Clinical Management of Combined Periodontal Conditions. (Abstract)

with enlarged, tender, bleeding gums, and loose teeth combined with a history of uncontrolled hypertension treated with calcium channel blockers.Incorporating the EBD process, a new 5-step framework is proposed: ask the clinical question, acquire and appraise the evidence, apply it in the clinical setting, and assess the subjective and objective outcomes. Articles on aggressive periodontitis and/or gingival enlargement were sought using the assistance of an expert librarian. The search was conducted (...) Using Evidence-Based Dentistry in the Clinical Management of Combined Periodontal Conditions. This report proposes a framework to integrate evidence-based dentistry (EBD) in a systematic approach in the clinical management of a patient diagnosed with drug-induced gingival hyperplasia combined with generalized aggressive periodontitis.This report illustrates the case of a 37-year-old female who presented to the Department of Periodontology at Tufts University School of Dental Medicine

2018 Journal of Evidence Based Dental Practice

278. Is there an association between depression and periodontitis? A birth cohort study. Full Text available with Trip Pro

of clinical attachment loss (CAL) and bleeding on probing (BOP) simultaneously. Serum levels of C-reactive protein and frequency of dental flossing were defined as mediators while confounders comprised a set of variables collected throughout the life-course of the participants. The parametric g-formula was used to test the direct, indirect and total effects of depression on periodontitis.539 participants were clinically examined. Individuals with depressive symptoms presented higher risk of periodontitis (...) Is there an association between depression and periodontitis? A birth cohort study. To investigate the association between depression and periodontitis among adults enrolled in the 1982 Pelotas Birth Cohort, Brazil.Major depressive episode (MDE) and severity of depressive symptoms obtained in 2012 were considered the exposure of this study. In 2013, periodontitis, the outcome of interest, was clinically assessed and two different case definitions were used: the CDC/AAP and a combination

2018 Journal of Clinical Periodontology

279. Time between recall visits and residual probing depths predict long-term stability in patients enrolled in supportive periodontal therapy. (Abstract)

with patients returning later (19.2%, ±7.6) (p < 0.0001). Additionally, patients attending >50% of their SPT visits earlier versus later demonstrated increased periodontal stability after 5 years (p = 0.0002) and a reduced frequency of tooth loss (0.60, ±0.93 versus 1.45, ±2.07) after 20 years (p < 0.0001).To reach and maintain periodontal stability during SPT, individual quantitative data from comprehensive residual PPD profiles may contribute to the improved planning of SPT intervals.© 2018 John Wiley (...) Time between recall visits and residual probing depths predict long-term stability in patients enrolled in supportive periodontal therapy. To relate the time between recall visits and residual periodontal probing depths (PPDs) to periodontal stability in patients enrolled in supportive periodontal therapy (SPT).Retrospective data on residual PPDs from 11,842 SPT visits were evaluated in SPT patients at the Medi School of Dental Hygiene (MSDH), Bern, Switzerland, 1985-2011. A residual PPD-based

2018 Journal of Clinical Periodontology

280. Garlic Product Impact on Periodontitis (GPIP)

). Subjects will be requested to use the products at home for the duration of the study according to the written and verbal usage instructions given to them during product distribution. At Baseline, Month 6, 12, and 18 subjects will receive oral soft tissue exams, and will have gingival inflammation, bleeding, and periodontal measurements made as described in below. Both groups will receive supragingival dental prophylaxes every 6 month consistent with local norms and standards. Products will be re (...) -supplied approximately every six months following Baseline. During study conduct, subjects with evidence of progressive periodontal disease (≥3 mm increases in pocket depth, attachment loss or recession) will be exited from the study and treated following local norms. Condition or disease Intervention/treatment Phase Periodontitis, Adult Dietary Supplement: Aged Garlic Extract Not Applicable Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial) Estimated

2018 Clinical Trials

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