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Periodontal Bleeding

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201. Efficacy of systemic antibiotics in nonsurgical periodontal therapy for diabetic subjects: a systematic review and meta-analysis.

with periodontitis were included. Trials published up to August 2016 were identified from MEDLINE, EMBASE and LILACS databases. Meta-analyses were conducted to determine changes in clinical attachment level (CAL), probing pocket depth (PPD), bleeding on probing (BOP) and gingival index (GI). Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines were followed in this review.Of the 164 papers potentially admissible to this systematic review, 15 articles on 11 randomised clinical (...) Efficacy of systemic antibiotics in nonsurgical periodontal therapy for diabetic subjects: a systematic review and meta-analysis. To evaluate the effects of systemic antibiotics as adjuncts to nonsurgical periodontal treatment (NSPT), as opposed to using NSPT alone, on periodontal clinical parameters of diabetic patients with periodontitis.Randomised controlled trials with a follow-up of 3 months or more, assessing the effects of NSPT in combination with antibiotics, in diabetic patients

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2018 International dental journal

202. Serum and salivary ferritin and Hepcidin levels in patients with chronic periodontitis and type 2 diabetes mellitus. (PubMed)

categorized into 4 groups based on the presence or absence of CP or T2DM. Demographics and general health parameters were recorded. Full-mouth clinical periodontal parameters including probing pocket depth, clinical attachment loss, bleeding index, and plaque index were recorded. Chemiluminescence microparticle immunoassay and enzyme-linked immunosorbent assay were used to detect ferritin and hepcidin concentrations, respectively, in serum and saliva.Serum ferritin and hepcidin levels in the CP and CP (...) Serum and salivary ferritin and Hepcidin levels in patients with chronic periodontitis and type 2 diabetes mellitus. Iron disorder and abnormal expression of hepcidin play important roles in many diseases, but it is still unclear in chronic periodontitis (CP) and type 2 diabetes mellitus (T2DM). We aimed to assess ferritin and hepcidin levels in serum and saliva of CP patients with or without T2DM.Serum and unstimulated whole saliva samples were collected from 88 participants, who were

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2018 BMC Oral Health

203. Insulin resistance predicts the risk of gingival/periodontal inflammation (PubMed)

Insulin resistance predicts the risk of gingival/periodontal inflammation Evaluate whether insulin resistance (IR) predicts the risk of oral inflammation, assessed as the number of sites with bleeding on probing (BOP) and number of teeth with probing pocket depths (PPD) ≥ 4 mm and BOP.Data on 870 overweight/obese diabetes free adults, aged 40-65 years from the San Juan Overweight Adults Longitudinal Study over a three-year period, was analyzed. Baseline IR, assessed using the Homeostasis Model (...) /periodontal inflammation in this population.© 2018 American Academy of Periodontology.

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2018 Journal of periodontology

204. One or two ligatures inducing periodontitis are sufficient to cause fatty liver (PubMed)

ligatures. The following parameters were assessed: gingival bleeding index, probing pocket depth, tooth mobility, alveolar bone loss, malondialdehyde (MDA) and myeloperoxidase (MPO) activity in periodontal tissue; histopathological evaluation of hepatic tissue (steatosis score); glutathione levels (GSH), MDA, MPO, cholesterol and triglycerides in the liver; and serum levels of alanine aminotransferase (ALT) and aspartate aminotransferase (AST).Periodontal evaluation data showed that the periodontitis (...) One or two ligatures inducing periodontitis are sufficient to cause fatty liver Periodontitis is a chronic disease that due to an intense inflammatory response triggers systemic changes such as hepatic alterations. This study aimed to compare hepatic damage in rats that received experimental periodontitis at one or two periodontal sites with ligatures.Eighteen rats were separated into three groups: control, without ligature; periodontitis 1, with one ligature; and periodontitis 2, with two

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2018 Medicina oral, patología oral y cirugía bucal

205. Periodontal healing following non-surgical repair of an old perforation with pocket formation and oral communication (PubMed)

Periodontal healing following non-surgical repair of an old perforation with pocket formation and oral communication Iatrogenic perforations negatively impact the outcome of endodontic treatments. Studies on prognostic factors showed that perforations in the coronal third of the root with periodontal pocket formation have an unfavorable prognosis. A 36-year-old female was referred for endodontic evaluation of tooth #13 with a history of an iatrogenic perforation, happened 3 years ago (...) . There was a sinus tract associated with perforation, 10 mm probing on the mesial and mesio-palatal, bleeding on probing, radiolucent lesion adjacent to the perforation and complete resorption of the interdental bone between teeth #13 and #12. After the treatment options were discussed, she chose to save the tooth. The tooth was accessed under rubber dam isolation, the perforation site was cleaned and disinfected using 0.5% sodium hypochlorite and sealed with calcium-enriched mixture cement. Eighteen months

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2018 Restorative dentistry & endodontics

206. Impact of periodontitis as representative of chronic inflammation on long-term clinical outcomes in patients with atrial fibrillation (PubMed)

, ECG and periodontitis database were reviewed from 2013 to 2015 to identify patients with AF. Those patients were divided into two groups according to the presence of periodontitis and clinical events including any arrhythmic attack, thromboembolic and bleeding and death were collected during a median of 18 months.Among 227 patients with AF, 47 (20.7%) patients had periodontitis. Major adverse cardiac events (MACE) were significantly higher in patients with periodontitis compared with those without (...) periodontitis (p<0.001). Arrhythmias including AF, atrial tachycardia, atrial premature beat, ventricular tachycardia and ventricular premature beat also occurred in 44 (93.6%) patients, which was higher significantly higher incidence in patients with periodontitis than in those without periodontitis (p<0.001). In univariate analysis, age, CHA2DS2-VASc, left atrial volume index (LAVi) and periodontitis were significantly associated with arrhythmic events and MACE including bleeding events, thromboembolic

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2018 Open heart

207. Circulation levels of acute phase proteins pentraxin 3 and serum amyloid A in atherosclerosis have correlations with periodontal inflamed surface area (PubMed)

levels of acute phase reactants (APR) and pro-inflammatory cytokines/mediators and lower anti-inflammatory cytokines/mediators in CAD patients. Material and Methods Patients aged from 30 to 75 years who underwent coronary angiography with CAD suspicion were included. Clinical periodontal parameters (probing depth - PD, clinical attachment loss, and bleeding on probing - BOP) were previously recorded and participants were divided into four groups after coronary angiography: Group 1: CAD (...) Circulation levels of acute phase proteins pentraxin 3 and serum amyloid A in atherosclerosis have correlations with periodontal inflamed surface area Objectives One of the plausible mechanisms in the relationship between periodontitis and coronary artery disease (CAD) is the systemic inflammatory burden comprised of circulating cytokines/mediators related to periodontitis. This study aims to test the hypothesis that periodontal inflamed surface area (PISA) is correlated with higher circulating

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2018 Journal of Applied Oral Science

208. Influence of Periodontal Disease Treatment on Serum Levels of Sirtuin 1 and Mannose-binding Lectin

or disease Intervention/treatment Phase Periodontal Diseases Procedure: treatment of periodontal disease Not Applicable Detailed Description: Inclusion criteria for PD were: presence of at least 15 teeth and clinical diagnosis of PD. Excluding third molars. This diagnosis was confirmed by the presence of at least 6 teeth with at least one noncontiguous interproximal site with Probing Pocket Depth (PPD) and Clinical Attachment Loss (CAL) ≥ 5 mm, as well as 30% of Sites with PPD and CAL ≥ 4mm and bleeding (...) Attachment Loss (CAL), plaque index (IP) and bleeding on probing (BOP), PPD and CAL measurements are rounded to the nearest millimeter using a North Carolina periodontal probe (Chicago, USA). Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial) Actual Enrollment : 80 participants Allocation: Non-Randomized Intervention Model: Parallel Assignment Masking: None (Open Label) Primary Purpose: Treatment Official Title: Influence of Periodontal Disease Treatment

2018 Clinical Trials

209. Comprehensive Treatment of Severe Periodontal and Periimplant Bone Destruction Caused by Iatrogenic Factors (PubMed)

Comprehensive Treatment of Severe Periodontal and Periimplant Bone Destruction Caused by Iatrogenic Factors Dental implant success requires placement after periodontal therapy, with adequate bone volume, plaque control, primary stability, control of risk factors, and use of well-designed prostheses. This report describes the surgical and prosthetic management of a patient with severe iatrogenic periodontal/periimplant bone destruction. Methods. A 55-year-old female smoker with fixed partial (...) dentures (FPDs) supported on teeth and implants presented with oral pain, swelling, bleeding, and a 10-year history of multiple implant placements and implants/prosthesis failures/replacements. Radiographs showed severe bone loss, subgingival caries, and periapical lesions. All implants and teeth were removed except implants #4 and #10 which served to retain an interim maxillary restoration. Bone defects were covered with nonresorbable dPTFE membranes. In the mandible, three new implants were placed

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2018 Case reports in dentistry

210. Knowledge of Medical Practitioners about Periodontal Diseases and Its Impact on Overall Health: A Cross-sectional Study (PubMed)

Knowledge of Medical Practitioners about Periodontal Diseases and Its Impact on Overall Health: A Cross-sectional Study Periodontal disease is defined as an inflammation of the gums that may result in loss of the tissues holding the teeth in its place. The signs and symptoms include red and/or swollen gums, bleeding gums, halitosis or in severe cases, loosening of teeth. Periodontal diseases act as a risk factor for several health conditions including diabetes and cardiovascular diseases (...) and it can even result in adverse pregnancy outcomes. Therefore, in this study, we aim to assess the knowledge of medical practitioners regarding periodontal diseases and its impact on overall health.We conducted a cross-sectional, questionnaire-based study that included 100 medical practitioners working in the Combined Military Hospital Lahore, Pakistan.In our study, 83.0% participants knew the definition of periodontal disease; 7.0% of the participants responded that they take their patient's

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2018 Cureus

211. Revitalization of necrotic mature permanent incisors with apical periodontitis: a case report (PubMed)

-traumatized incisors with closed apex with apical periodontitis. A 2-visit treatment procedure was employed. At initial visit, the root canals were copiously irrigated, followed by placement of a triple antibiotic paste containing ciprofloxacin, metronidazole, and clindamycin into the root canals. After 4 weeks, the antibiotic paste was removed, and apical bleeding was initiated with size 10 hand files beyond the apices. The root canals were coronally sealed with mineral trioxide aggregate, and the access (...) Revitalization of necrotic mature permanent incisors with apical periodontitis: a case report Despite considerable focus on the regenerative endodontic treatment of immature teeth with necrotic infected pulps and apical periodontitis, little data exist with regard to its possible implementation in necrotic permanent teeth with complete apical and radicular development. The present report describes the procedures and outcome of a regenerative endodontic treatment approach in 2 previously

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2018 Restorative dentistry & endodontics

212. Evaluation of the Possible Relationship Between Preeclampsia and Periodontal Disease

Evaluation of the Possible Relationship Between Preeclampsia and Periodontal Disease Evaluation of the Possible Relationship Between Preeclampsia and Periodontal Disease - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before (...) adding more. Evaluation of the Possible Relationship Between Preeclampsia and Periodontal Disease The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT03603236 Recruitment Status : Recruiting First Posted : July 27, 2018 Last

2018 Clinical Trials

213. Snuff Use, Smoking, Periodontal Health and Premature Death: 30-year Study

) periodontal probe (Hu-friedy, Chicago, Ill., USA). Missing teeth [ Time Frame: 1985 ] Pure smokers had more likely missing teeth than subjects in other groups. Missing teeth were calculated my dentist in clinical examination. Gingival Index (GI) [ Time Frame: 1985 ] Dual-users, pure snuffers and pure smokers had higher GI scores than non-users. GI was scored from 0 (no gum bleeding) to 3 (abundant gum bleeding) Premature death [ Time Frame: From year 1985 to year 2015 ] Snuff users or smokers did not die (...) Snuff Use, Smoking, Periodontal Health and Premature Death: 30-year Study Snuff Use, Smoking, Periodontal Health and Premature Death: 30-year Study - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Snuff Use

2018 Clinical Trials

214. Enamel Matrix Derivatives on Systemic Inflammation After Periodontal Therapy

Enamel Matrix Derivatives on Systemic Inflammation After Periodontal Therapy Enamel Matrix Derivatives on Systemic Inflammation After Periodontal Therapy - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more (...) . Enamel Matrix Derivatives on Systemic Inflammation After Periodontal Therapy (PERIOEMD-2) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT03544931 Recruitment Status : Completed First Posted : June 4, 2018 Last Update Posted : July 6, 2018 Sponsor: University of Pisa Collaborator: Institut Straumann

2018 Clinical Trials

215. TNF-α/HIF-1α/VEGF Pathway in Periodontal Diseases

. Whole-mouth and site-specific clinical periodontal parameters including probing depth, clinical attachment level, bleeding on probing, gingival index and plaque index were recorded. GCF and salivary HIF-1α, VEGF and TNF-α levels were measured by enzyme-linked immunosorbent assay. Statistical analysis was performed by using non-parametric tests. Condition or disease Periodontal Diseases Study Design Go to Layout table for study information Study Type : Observational Actual Enrollment : 87 (...) TNF-α/HIF-1α/VEGF Pathway in Periodontal Diseases TNF-α/HIF-1α/VEGF Pathway in Periodontal Diseases - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. TNF-α/HIF-1α/VEGF Pathway in Periodontal Diseases

2018 Clinical Trials

216. Imaging Analysis Following Periodontal Surgery

: All Accepts Healthy Volunteers: No Criteria Inclusion Criteria: Systemically healthy males and females ≥ 30 years of age. Participants must be willing to read, and sign a copy of the "Informed Consent Form" (ICF) form after reading the, "Patient Information Leaflet" (PIS), and after the nature of the study has been fully explained. Participants must present with clinical and radiographic evidence of periodontitis, with one interdental area of Periodontal Pocket Depth (PPD) ≥6mm, Bleeding (...) Imaging Analysis Following Periodontal Surgery Imaging Analysis Following Periodontal Surgery - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Imaging Analysis Following Periodontal Surgery The safety

2018 Clinical Trials

217. Treatment of Periodontitis With Er:YAG Laser

% of the present teeth with Probing depths of > 4mm and Bleeding on Probing Non-smoker and former smokers (stopped smoking > 1 year) Participants that have not received any periodontal treatment in the past 3 months Exclusion Criteria: Participants with uncontrolled systemic diseases that could affect the treatment outcome such as Diabetes with HbA1c > 7.0 percent, rheumatoid arthritis, immunosuppression, HIV with detectable viral loads Participants requiring antibiotic prophylaxis for any cardiovascular (...) Treatment of Periodontitis With Er:YAG Laser Treatment of Periodontitis With Er:YAG Laser - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Treatment of Periodontitis With Er:YAG Laser The safety

2018 Clinical Trials

218. Efficacy of Azithromycin as an Adjunct to Non-Surgical Periodontal Treatment

(Stage III grade B). A double-blind, randomized, controlled trial was conducted with 18 voluntary patients with a history of moderate to severe chronic periodontitis, who met the inclusion and exclusion criteria and signed an informed consent. The intervention group received Scaling and Root Planning (SRP) plus azithromycin, and the control group received SRP plus placebo. Probing depth (PD), Clinical Attachment Level (CAL), Biofilm Index (BI) and Bleeding on Probing (BOP) were evaluated as clinical (...) between both treatment groups. Difference between groups for the bleeding on probing (BOP) Index, in stage II or III grade B periodontitis patients before and 1, 3 and 6 month after performing SRP with placebo or azithromycin. [ Time Frame: Baseline,1, 3 and 6 month ] Before,1, 3 and 6 month after performing SRP, BOP was measured in all the patients in the study. BOP is the percentage of surfaces that bleed when probing. It was recorded during PD measurement with a North Carolina periodontal probe (Hu

2018 Clinical Trials

219. Evaluation of the Possible Relationship Between Periodontal Disease and Preterm Labor

Evaluation of the Possible Relationship Between Periodontal Disease and Preterm Labor Evaluation of the Possible Relationship Between Periodontal Disease and Preterm Labor - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before (...) adding more. Evaluation of the Possible Relationship Between Periodontal Disease and Preterm Labor The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT03610841 Recruitment Status : Recruiting First Posted : August 1, 2018 Last

2018 Clinical Trials

220. Intense Education of Periodontal Health Maintenance

Frame: 9 month ] 1. Improvement of periodontal condition Response to periodontal treatment will be determined by a composite measure including 1) Plaque Index; 2) Gingival index; 3) Cemento-enamel junction, gingival margin, probing, and bleeding on probing from six sites on all teeth. The patients will be considered to have improved, non-changed, and worsening periodontitis, according to clinical measurements and comparison them with those before treatments. Eligibility Criteria Go to Information (...) Intense Education of Periodontal Health Maintenance Intense Education of Periodontal Health Maintenance - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Intense Education of Periodontal Health Maintenance

2018 Clinical Trials

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