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Periodic Limb Movement

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161. Common neural correlates of real and imagined movements contributing to the performance of brain–machine interfaces Full Text available with Trip Pro

Common neural correlates of real and imagined movements contributing to the performance of brain–machine interfaces The relationship between M1 activity representing motor information in real and imagined movements have not been investigated with high spatiotemporal resolution using non-invasive measurements. We examined the similarities and differences in M1 activity during real and imagined movements. Ten subjects performed or imagined three types of right upper limb movements. To infer (...) increased around the hand and arm areas during real and imagined movements and that these are spatially correlated. The temporal correlation of decoding accuracy significantly increased around the hand and arm areas, except for the period immediately after response onset. Our results suggest that cM1 is involved in similar neural activities related to the representation of motor information during real and imagined movements, except for presence or absence of sensory-motor integration induced by sensory

2016 Scientific reports

162. Sensorimotor Synchronization with Different Metrical Levels of Point-Light Dance Movements Full Text available with Trip Pro

the trunk bounced at every beat and the limbs moved at every second beat, forming two metrical periodicities. Participants tapped synchronously to the bounce of the trunk with or without the limbs moving in the stimuli (Experiment 1), or tapped synchronously to the leg movements with or without the trunk bouncing simultaneously (Experiment 2). Results showed that, while synchronization with the bounce (lower-level pulse) was not influenced by the presence or absence of limb movements (metrical accent (...) Sensorimotor Synchronization with Different Metrical Levels of Point-Light Dance Movements Rhythm perception and synchronization have been extensively investigated in the auditory domain, as they underlie means of human communication such as music and speech. Although recent studies suggest comparable mechanisms for synchronizing with periodically moving visual objects, the extent to which it applies to ecologically relevant information, such as the rhythm of complex biological motion, remains

2016 Frontiers in human neuroscience

163. Rapid Eye Movement Sleep Abnormalities in Children with Pediatric Acute-Onset Neuropsychiatric Syndrome (PANS) Full Text available with Trip Pro

had evidence of rapid eye movement (REM) sleep motor disinhibition, as characterized by excessive movement, laughing, hand stereotypies, moaning, or the continuation of periodic limb movements during sleep (PLMS) into REM sleep.This study shows various forms of REM sleep motor disinhibition present in a population of children with PANS.© 2016 American Academy of Sleep Medicine. (...) Rapid Eye Movement Sleep Abnormalities in Children with Pediatric Acute-Onset Neuropsychiatric Syndrome (PANS) Polysomnographic investigation of sleep architecture in children presenting with pediatric acute-onset neuropsychiatric syndrome (PANS).Fifteen consecutive subjects meeting criteria for PANS (mean age = 7.2 y; range 3-10 y) underwent single-night full polysomnography (PSG) read by a pediatric neurologist.Thirteen of 15 subjects (87%) had abnormalities detected with PSG. Twelve of 15

2016 Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine

164. Mortality and Its Risk Factors in Patients with Rapid Eye Movement Sleep Behavior Disorder Full Text available with Trip Pro

was significantly associated with age (hazard ratio [HR] = 1.05; 95% CI, 1.01-1.10), living alone (HR = 2.04; 95% CI, 1.39-2.99), chronic obstructive pulmonary disease (HR = 3.38; 95% CI, 1.21-9.46), cancer (HR = 10.09; 95% CI, 2.65-38.42), periodic limb movements during sleep (HR = 3.06; 95% CI, 1.50-6.24), and development of neurodegenerative diseases (HR = 2.84; 95% CI, 1.47-5.45) and dementia (HR = 2.66; 95% CI, 1.39-5.08).Patients with RBD have a higher mortality rate than the general population only (...) Mortality and Its Risk Factors in Patients with Rapid Eye Movement Sleep Behavior Disorder To determine the mortality and its risk factors in patients with rapid eye movement (REM) sleep behavior disorder (RBD).A total of 205 consecutive patients with video-polysomnography confirmed RBD (mean age = 66.4 ± 10.0 y, 78.5% males) were recruited. Medical records and death status were systematically reviewed in the computerized records of the health care system. Standardized mortality ratio (SMR

2016 Sleep

165. Effects of Training Rhythmic and Discrete Aiming Movements on Arm Control and Functionality After Stroke

, unilateral and bilateral motor tasks as well as oriented tasks training upper limb with a focus on functional tasks. The other groups will receive additional intervention consisting of aiming movement practice according two different protocols: discrete movements to targets placed in different directions and distances; and rhythmic movements also to targets placed in different directions and distances. Both additional interventional interventions will be conducted for 30 minutes over a 5 week-period (...) of treatment over a period of five weeks (two sessions/week) Experimental: discrete movement training group Aiming movements training with the affected upper limb (unilateral training) or both limbs (bilateral training) on the surface of a table. The starting point of the movement and its target are predetermined. Targets will be placed in different directions and distances from the starting point and the therapist ask for variations on speed and assistance, if necessary. Other: Discrete movement training

2016 Clinical Trials

166. Effects of Cryotherapy on Ankle Movements and Gait of Spastic Hemiparetic Subjects

Effects of Cryotherapy on Ankle Movements and Gait of Spastic Hemiparetic Subjects Effects of Cryotherapy on Ankle Movements and Gait of Spastic Hemiparetic Subjects - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before (...) adding more. Effects of Cryotherapy on Ankle Movements and Gait of Spastic Hemiparetic Subjects The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT02736747 Recruitment Status : Active, not recruiting First Posted : April 13, 2016 Last Update Posted : August 2, 2017 Sponsor: Carolina Carmona de Alcântara

2016 Clinical Trials

167. Constraint-induced Movement Therapy and Self-regulation for Children With Cerebral Palsy

Sydney Collaborator: The Hong Kong Polytechnic University Information provided by (Responsible Party): Karen Liu, University of Western Sydney Study Details Study Description Go to Brief Summary: This study examines the effect of combining modified constraint-induced movement therapy (mCIMT) and self-regulation (SR) in promoting upper limb function of children with hemiplegic cerebral palsy (CP) studying in a school-based setting. Condition or disease Intervention/treatment Phase Cerebral Palsy Other (...) period to measure the carry-over effect. The OT program consists of training on unimanual and bimanual tasks for 1 to 2 hours a week with daily home exercise. The mCIMT + SR program involves restraint of the unaffected upper limb of children using a cotton sling for 6 hours per day for 15 days. A one-hour structured task practice with the use of SR is provided during each 6-hour restraint. The Bruininks-Oseretsky Test of Motor Proficiency, the Jebsen-Taylor Test of Hand Function, the Caregiver

2016 Clinical Trials

168. Upper Limb Outcome Measures Used in Stroke Rehabilitation Studies: A Systematic Literature Review Full Text available with Trip Pro

measures: the FMT was often combined with the Motor Activity Log (MAL), the Wolf Motor Function Test and the Action Research Arm Test, but infrequently combined with the Motor Assessment Scale or the Nine Hole Peg Test. Key components of manual dexterity such as selective finger movements were rarely measured. Frequency of use increased over a twelve-year period for the FMT and for assessments of kinematics, whereas other measures, such as the MAL and the Jebsen Taylor Hand Test showed decreased use (...) Upper Limb Outcome Measures Used in Stroke Rehabilitation Studies: A Systematic Literature Review Establishing which upper limb outcome measures are most commonly used in stroke studies may help in improving consensus among scientists and clinicians.In this study we aimed to identify the most commonly used upper limb outcome measures in intervention studies after stroke and to describe domains covered according to ICF, how measures are combined, and how their use varies geographically and over

2016 PloS one

169. Robotic lower limb prosthesis design through simultaneous computer optimizations of human and prosthesis costs Full Text available with Trip Pro

Robotic lower limb prosthesis design through simultaneous computer optimizations of human and prosthesis costs Robotic lower limb prostheses can improve the quality of life for amputees. Development of such devices, currently dominated by long prototyping periods, could be sped up by predictive simulations. In contrast to some amputee simulations which track experimentally determined non-amputee walking kinematics, here, we explicitly model the human-prosthesis interaction to produce (...) a prediction of the user's walking kinematics. We obtain simulations of an amputee using an ankle-foot prosthesis by simultaneously optimizing human movements and prosthesis actuation, minimizing a weighted sum of human metabolic and prosthesis costs. The resulting Pareto optimal solutions predict that increasing prosthesis energy cost, decreasing prosthesis mass, and allowing asymmetric gaits all decrease human metabolic rate for a given speed and alter human kinematics. The metabolic rates increase

2016 Scientific reports

170. Phenotypical expression of reduced mobility during limb ontogeny in frogs: the knee-joint case Full Text available with Trip Pro

/tendons have not yet developed and therefore are not affected by immobilization. These results suggest the existence of a specific period of phenotypical expression in which normal limb movement is necessary for the correct development of the joint tissue framework. (...) Phenotypical expression of reduced mobility during limb ontogeny in frogs: the knee-joint case Movement is one of the most important epigenetic factors for normal development of the musculoskeletal system, particularly during genesis and joint development. Studies regarding alterations to embryonic mobility, performed on anurans, chickens and mammals, report important phenotypical similarities as a result of the reduction or absence of this stimulus. The precise stage of development at which

2016 PeerJ

171. Monitoring Upper Limb Recovery after Cervical Spinal Cord Injury: Insights beyond Assessment Scores Full Text available with Trip Pro

Monitoring Upper Limb Recovery after Cervical Spinal Cord Injury: Insights beyond Assessment Scores Preclinical investigations in animal models demonstrate that enhanced upper limb (UL) activity during rehabilitation promotes motor recovery following spinal cord injury (SCI). Despite this, following SCI in humans, no commonly applied training protocols exist, and therefore, activity-based rehabilitative therapies (ABRT) vary in frequency, duration, and intensity. Quantification of UL recovery (...) is limited to subjective questionnaires or scattered measures of muscle function and movement tasks.To objectively measure changes in UL activity during acute SCI rehabilitation and to assess the value of wearable sensors as novel measurement tools that are complimentary to standard clinical assessments tools.The overall amount of UL activity and kinematics of wheeling were measured longitudinally with wearable sensors in 12 thoracic and 19 cervical acute SCI patients (complete and incomplete

2016 Frontiers in neurology

172. Neuromodulation of Limb Proprioceptive Afferents Decreases Apnea of Prematurity and Accompanying Intermittent Hypoxia and Bradycardia Full Text available with Trip Pro

during vibration periods, relative to baseline (p<0.005). Significantly fewer SpO2 declines occurred with vibration (p<0.05), relative to control periods. Significantly fewer bradycardic events occurred during vibration periods, relative to no vibration periods (p<0.05).In premature neonates, limb proprioceptive stimulation, simulating limb movement, reduces breathing pauses and IH episodes, and lowers the number of bradycardic events that accompany aberrant breathing episodes. This low-cost (...) Neuromodulation of Limb Proprioceptive Afferents Decreases Apnea of Prematurity and Accompanying Intermittent Hypoxia and Bradycardia Apnea of Prematurity (AOP) is common, affecting the majority of infants born at <34 weeks gestational age. Apnea and periodic breathing are accompanied by intermittent hypoxia (IH). Animal and human studies demonstrate that IH exposure contributes to multiple pathologies, including retinopathy of prematurity (ROP), injury to sympathetic ganglia regulating

2016 PloS one Controlled trial quality: uncertain

173. Combining Non-Invasive Vagus Nerve Stimulation and Robotic Training in Upper Limb-Impaired Chronic Stroke Patients

Combining Non-Invasive Vagus Nerve Stimulation and Robotic Training in Upper Limb-Impaired Chronic Stroke Patients Combining Non-Invasive Vagus Nerve Stimulation and Robotic Training in Upper Limb-Impaired Chronic Stroke Patients - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number (...) of saved studies (100). Please remove one or more studies before adding more. Combining Non-Invasive Vagus Nerve Stimulation and Robotic Training in Upper Limb-Impaired Chronic Stroke Patients The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT02878720 Recruitment Status : Unknown Verified August 2016

2016 Clinical Trials

174. Transcranial Magnetic Stimulation (TMS) for Upper Limb Dysfunction in Spinal Cord Injury: a Feasibility Study

acute (<3 months) SCI patients Implanted electrical devices such as pacemakers, Concomitant neurological conditions, including any history of epilepsy Significant joint-related limitation of passive range of movement Unable to attend all TMS sessions Pregnancy Inability to tolerate TBS Significant upper limb contractures Contacts and Locations Go to Information from the National Library of Medicine To learn more about this study, you or your doctor may contact the study research staff using (...) Transcranial Magnetic Stimulation (TMS) for Upper Limb Dysfunction in Spinal Cord Injury: a Feasibility Study Transcranial Magnetic Stimulation (TMS) for Upper Limb Dysfunction in Spinal Cord Injury: a Feasibility Study - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies

2016 Clinical Trials

175. Upper Limb Botulinum Toxin Injection Combined With Self Rehabilitation

(Boston Diagnostic Aphasia Examination(BDAE) <3) Osteoarticular lesion which contraindicates part of the rehabilitation involved in the study Patients with other interventions planned prior to the end of the study period (orthosis, surgery etc.) Surgery to the paretic limb treated in the study less than 6 months previously Contra-indications to botulinum toxin Contacts and Locations Go to Information from the National Library of Medicine To learn more about this study, you or your doctor may contact (...) Upper Limb Botulinum Toxin Injection Combined With Self Rehabilitation Upper Limb Botulinum Toxin Injection Combined With Self Rehabilitation - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Upper Limb

2016 Clinical Trials

176. Impact of a New Technology to Functional Recovery Upper Limb in Post Stroke Patients.

. The protocol (N° U0074917/11110) was approved by the Local Ethical Committee of Bergamo, Italy. A number of clinical trials have shown significant advances in upper limb recovery with the use of different sensory - motor techniques, including intensive repetitive movement, constraint-induced movement therapy, functional electrical stimulation treatment, the use of robot-assisted therapy in association with virtual reality. Robot-assisted virtual reality intervention has been shown more effective than (...) : Armeo Spring All patients of experimental group were treated according to an established protocol for ARMEO Spring. In the first session the device was adjusted for patients arms. The physiotherapist controlled functional space of upper limb movement and correct position of working station. Each training session consisted of two parts with 30 minutes per session with "Armeo Spring" and 30 minutes per session with conventional treatment 5 days per week, for 6 weeks. Device: Armeo Spring All patients

2016 Clinical Trials

177. Recovery of Upper Limb Function in Persons With Spinal Cord Injury: Lead-In Study

and right upper extremities) as clinically indicated for each study participant. Over the course of 20 one hour sessions, participants will progress through the various movement sequences aimed at regaining natural, unassisted voluntary movement in the affected limb(s). The MyndMove therapy will be in addition to the conventional upper limb rehabilitation therapy the participant will be prescribed to undertake at their local institution. From previous experience, the first signs of function recovery may (...) to evaluate improvements in the gross motor function of the unilateral grasp due to FES for reaching and grasping treatment. Hand functions that will be tested with the TRI-HFT are: lateral or pulp pinch, and palmar grasps. Change in participant's grasp, grip, pinch and gross movement of the arm and upper limb using the Action Research Arm Test (ARAT). [ Time Frame: Change from baseline to 4/7 weeks ] A test developed to assess the upper limb function in stroke and SCI patients. It consists of four sub

2016 Clinical Trials

178. NEurocontrolled BIdirectional Artificial Upper Limb and Hand prosthesiS

afferent pathway within the residual limb. The NEBIAS proposal is also aimed at finding out the 'language' intrinsically linking central nervous system with peripheral nerve signals in order to govern simple and complex hand/fingers movements. To reach this goal, a variety of techniques exploring brain and nerve functions will be assembled and integrated; this includes the analysis of electromagnetic brain and nerve signals, as well as of movement-related changes in brain's blood flow/metabolism (...) NEurocontrolled BIdirectional Artificial Upper Limb and Hand prosthesiS NEurocontrolled BIdirectional Artificial Upper Limb and Hand prosthesiS - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more

2016 Clinical Trials

179. Mirror Therapy: Effects on Functional Recuperation of Severe Upper Limb Paresis After Stroke

a regimen of 30 minutes of therapy, 5 times a week, for 4 weeks on top of conventional therapy. One group performs MT and the other one performs a therapy in which the same movements are performed, but without the use of a mirror, with unrestricted view of both limbs. Allocation to each group will be randomized. Arm function will be evaluated by use of a scale before, during and after the 4 week period. The assessor for the primary outcome measure will not know in which group the patient (...) while hiding the paretic one, and then asking him to perform movements of his healthy arm while looking at its reflection in the mirror. Active Comparator: Control Therapy (CT) Standard therapy + 30 min/day of CT. Other: Control Therapy Performance of the same movements as the experimental group without the mirror or instructions as to where to look, 5 days/week, for 4 weeks. Outcome Measures Go to Primary Outcome Measures : Change in Fugl Meyer Assessment - Upper Limb (FMA-UE) [ Time Frame

2016 Clinical Trials

180. Study to Evaluate Effects of DYSPORT® Injected in Lower and Upper Limb Combined With Guided Self-Rehabilitation Contract (GSC)

Status : Completed First Posted : November 21, 2016 Last Update Posted : December 13, 2018 Sponsor: Ipsen Information provided by (Responsible Party): Ipsen Study Details Study Description Go to Brief Summary: The purpose of this clinical study is to assess whether AbobotulinumtoxinA (Dysport®) injections in upper and lower limbs accompanied with a personal exercise plan called "Guided Self-rehabilitation Contract" (GSC) can improve voluntary movements in subjects with hemiparesis. Condition (...) : The percentage of responder subjects after the second injection, according to composite active range of motion (AROM) in the primary treatment target (TT) limb [ Time Frame: Week 6 cycle 2 (each cycle can have a duration of from 12 to 20 weeks) ] Composite AROM will be measured by goniometer in the primary TT limb, using zero as the theoretical position of minimal stretch for the muscle assessed. The subject will be asked to perform the active movement as far as possible against that muscle and the angle

2016 Clinical Trials

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