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Periodic Limb Movement

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141. Effects of repeated abobotulinumtoxinA injections in upper limb spasticity (PubMed)

and continuous improvements in active movements and perceived and active function were associated with repeated abobotulinumtoxinA injections in upper limb muscles. Muscle Nerve 57: 245-254, 2018.© 2017 The Authors Muscle & Nerve Published by Wiley Periodicals, Inc. (...) Effects of repeated abobotulinumtoxinA injections in upper limb spasticity The efficacy of single injections of abobotulinumtoxinA (Dysport) is established in adults with upper limb spasticity. In this study we assessed the effects of repeated injections of abobotulinumtoxinA over 1 year.Patients (n = 258, safety population) received 500 U, 1,000 U, or 1,500 U (1,500-U dose included 500-U shoulder injections) for up to 4 or 5 treatment cycles. Assessments included treatment-emergent adverse

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2017 Muscle & nerve Controlled trial quality: uncertain

142. Restoration of motor control and proprioceptive and cutaneous sensation in humans with prior upper-limb amputation via multiple Utah Slanted Electrode Arrays (USEAs) implanted in residual peripheral arm nerves (PubMed)

sensation as feedback to complete a 1-DOF closed-loop virtual-hand movement task. There were no observed long-term functional deficits due to the USEA implants.Implantation of high-channel-count USEAs enables multi-degree-of-freedom control of virtual prosthetic hand movement and restoration of a rich selection of both proprioceptive and cutaneous sensory percepts spanning the hand during the short 4-5 week post-implant period. Future USEA use in longer-term implants and in closed-loop may enable (...) Restoration of motor control and proprioceptive and cutaneous sensation in humans with prior upper-limb amputation via multiple Utah Slanted Electrode Arrays (USEAs) implanted in residual peripheral arm nerves Despite advances in sophisticated robotic hands, intuitive control of and sensory feedback from these prostheses has been limited to only 3-degrees-of-freedom (DOF) with 2 sensory percepts in closed-loop control. A Utah Slanted Electrode Array (USEA) has been used in the past to provide

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2017 Journal of neuroengineering and rehabilitation

143. Prescribed exercise programs may not be effective in reducing impairments and improving activity during upper limb fracture rehabilitation: a systematic review. (PubMed)

. There was preliminary evidence from one trial that exercise to the non-injured arm during immobilisation might lead to short-term benefits on increasing grip strength and range of movement following distal radius fracture. Less than 40% of included trials reported adequate exercise program descriptions to allow replication according to the TIDieR checklist.There is emerging evidence that current prescribed exercise regimens may not be effective in reducing impairments and improving activity following an upper limb (...) fracture. Starting exercise early combined with a shorter immobilisation period is more effective than starting exercise after a longer immobilisation period.CRD42016041818. [Bruder AM, Shields N, Dodd KJ, Taylor NF (2017) Prescribed exercise programs may not be effective in reducing impairments and improving activity during upper limb fracture rehabilitation: a systematic review. Journal of Physiotherapy 63: 205-220].Copyright © 2017 Australian Physiotherapy Association. Published by Elsevier B.V. All

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2017 Journal of physiotherapy

144. A Phase III Study to Evaluate the Efficacy and Safety of GSK1358820 in Subjects With Post-stroke Upper Limb Spasticity

A which can help to increase the maximum dose per administration to 400 units from 240 units as the treatment with 240 units is considered insufficient in subjects with post-stroke upper limb spasticity. Approximately 120 subjects will be randomized to receive either 400 or 240 units of botulinum toxin A in double blind phase followed by open-label phase in which 400 units of the study treatment will be injected in both the groups. The study period will be up to 52 weeks, consisting of a screening (...) tones. Changes from Baseline in disability assessment scale (DAS) [ Time Frame: Baseline and up to week 48 ] DAS scores of hygiene, pain, dressing, and limb posture will be assessed using a 4-point scale (0=No functional disability to 3=Severe disability). Prior to the first injection, the investigator, in consultation with the subject, will select one disability assessment parameter and will assess it as a "main assessment parameter" which will remain unchanged throughout the study period. Number

2017 Clinical Trials

145. Daily Intermittent Hypoxia and Task-Specific Upper Limb Training in Persons With Chronic Incomplete SCI

in individuals with chronic, incomplete SCI. Previous work already determined that breathing low levels of oxygen for short periods of time (also known as acute intermittent hypoxia) can improve lower limb motor function in persons with spinal injury. Specifically, this study is being done to determine if pre-treatment with intermittent hypoxia can enhance the beneficial effects of upper limb training on the restoration of limb function in persons with spinal injury. This is a blinded study, which means (...) Daily Intermittent Hypoxia and Task-Specific Upper Limb Training in Persons With Chronic Incomplete SCI Daily Intermittent Hypoxia and Task-Specific Upper Limb Training in Persons With Chronic Incomplete SCI - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100

2017 Clinical Trials

146. Upper Limb Function After Breast Cancer Surgery: the Role of Post-operative Physical Therapy Intervention

, restrictions of arm and shoulder movement were reported in 35% of patients, lymphedema in 15 - 25% of women who undergo axillary lymph node dissection and in about 6% of women who undergo sentinel lymph node biopsy. Lymphedema results in physical impairments including compromised function, diminished strength, fatigue, and pain in the affected arm . The axillary web syndrome is a self-limiting and frequently overlooked cause of significant morbidity in the early postoperative period after breast cancer (...) that underwent breast cancer surgery and immediate reconstruction without exercise and discharged without instructions. Outcome Measures Go to Primary Outcome Measures : Mobility of upper limb [ Time Frame: six month ] The mobility of the shoulder will be evaluates in all movements Secondary Outcome Measures : lymphedema [ Time Frame: 6 month ] Evaluation of lymphedema will be classified in 4 degrees Shoulder pain [ Time Frame: 6 month ] The intensity of pain and chronological modification will be monitored

2017 Clinical Trials

147. Myoelectric Upper Limb Orthosis Use by Persons With Traumatic Brain Injury

/medications planned during study period skin rash or open wound on impaired arm inability to detect light touch or pain on impaired arm involuntary movements of the impaired arm pain or hypersensitivity in the impaired arm inability to understand English Contacts and Locations Go to Information from the National Library of Medicine To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor. Please refer to this study by its (...) Myoelectric Upper Limb Orthosis Use by Persons With Traumatic Brain Injury Myoelectric Upper Limb Orthosis Use by Persons With Traumatic Brain Injury - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more

2017 Clinical Trials

148. A critical period of corticomuscular and EMG–EMG coherence detection in healthy infants aged 9–25 weeks (PubMed)

A critical period of corticomuscular and EMG–EMG coherence detection in healthy infants aged 9–25 weeks The early postnatal development of functional corticospinal connections in human infants is not fully clarified. Corticospinal drive to upper and lower limb muscle shows developmental changes with an increased functional coupling in infants between 9 and 25 weeks in the beta frequency band. The changes in functional coupling coincide with the developmental period where fidgety movements (...) -amplitude, broad-duration (40-50 ms) central peak of EMG-EMG synchronization was observed for infants younger than 9 weeks, whereas a short-lasting (10-20 ms) central peak was observed for EMG-EMG synchronization in older infants. This peak was largest for infants aged 9-25 weeks. These data suggest that the corticospinal drive to lower and upper limb muscles shows significant developmental changes with an increase in functional coupling in infants aged 9-25 weeks, a period which coincides partly

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2017 The Journal of physiology

149. Efficacy of wearing compression garments during post-exercise period after two repeated bouts of strenuous exercise: a randomized crossover design in healthy, active males (PubMed)

for hamstring (P = 0.047).Wearing a whole-body CG during the post-exercise period after two bouts of strenuous exercise sessions separated with 4 h of rest did not promote recovery of muscle function for lower limb muscles nor did it attenuate exercise-induced muscle damage in physically active males. (...) Efficacy of wearing compression garments during post-exercise period after two repeated bouts of strenuous exercise: a randomized crossover design in healthy, active males The efficacy of wearing [a] compression garment (CG) between repeated bouts of exercise within a same day has not been fully understood. The present study determined the effect of wearing a CG after strenuous exercise sessions (consisting of sprint exercise, resistance exercise, drop jump) twice a day on exercise performance

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2017 Sports medicine - open Controlled trial quality: uncertain

150. Effects of low-frequency repetitive transcranial magnetic stimulation and neuromuscular electrical stimulation on upper extremity motor recovery in the early period after stroke: a preliminary study. (PubMed)

in this randomized controlled trial. Experimental group 1 received low frequency (LF) rTMS to the primary motor cortex of the unaffected side + physical therapy (PT) including activities to improve strength, flexibility, transfers, posture, balance, coordination, and activities of daily living, mainly focusing on upper limb movements; experimental group 2 received the same protocol combined with NMES to hand extensor muscles; and the control group received only PT. Functional magnetic resonance imaging (fMRI (...) Effects of low-frequency repetitive transcranial magnetic stimulation and neuromuscular electrical stimulation on upper extremity motor recovery in the early period after stroke: a preliminary study. To assess the efficacy of inhibitory repetitive transcranial magnetic stimulation (rTMS) and neuromuscular electrical stimulation (NMES) on upper extremity motor function in patients with acute/subacute ischemic stroke.Twenty-five ischemic acute/subacute stroke subjects were enrolled

2017 Topics in stroke rehabilitation Controlled trial quality: uncertain

151. Human Umbilical Cord Mesenchymal Stem Cell Therapy for Cerebral Infarction Patients in Convalescent Period.

: no obvious improvement or condition worsened. Limb motor function analysis [ Time Frame: 6 months ] Using fugl-meyer assessment evaluate motor function. Mild movement disorder: 96 - 99; Moderate movement disorder: 85 - 95; Obvious movement disorder: 50 - 84; Serious movement disorder: < 50 Barthel Index analysis [ Time Frame: 6 months ] Obvious effective: Barthel Index score between 96 - 99, patient with self care ability. Effective:Barthel Index score between 70 - 89, patient with condition improved (...) Human Umbilical Cord Mesenchymal Stem Cell Therapy for Cerebral Infarction Patients in Convalescent Period. Human Umbilical Cord Mesenchymal Stem Cell Therapy for Cerebral Infarction Patients in Convalescent Period. - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies

2017 Clinical Trials

152. Constraint-induced movement therapy for the upper paretic limb in acute or sub-acute stroke: a systematic review. (PubMed)

Constraint-induced movement therapy for the upper paretic limb in acute or sub-acute stroke: a systematic review. Constraint-induced movement therapy is a commonly used intervention to improve upper limb function after stroke. However, the effectiveness of constraint-induced movement therapy and its optimal dosage during acute or sub-acute stroke is still under debate. To examine the literature on the effects of constraint-induced movement therapy in acute or sub-acute stroke. A literature (...) therapy. This meta-analysis demonstrates a trend toward positive effects of high-intensity and low-intensity constraint-induced movement therapy in acute or sub-acute stroke, but also suggests that low-intensity constraint-induced movement therapy may be more beneficial during this period than high-intensity constraint-induced movement therapy. However, these results were based on a small number of studies. Therefore, more trials are needed applying different doses of therapy early after stroke

2011 International journal of stroke : official journal of the International Stroke Society

153. Periodic Limb Movement Disorder (PLMD) and Restless Legs Syndrome (RLS)

Periodic Limb Movement Disorder (PLMD) and Restless Legs Syndrome (RLS) Periodic Limb Movement Disorder (PLMD) and Restless Legs Syndrome (RLS) - Neurologic Disorders - MSD Manual Professional Edition Brought to you by The trusted provider of medical information since 1899 SEARCH SEARCH MEDICAL TOPICS Common Health Topics Resources QUIZZES & CASES Quizzes Cases The trusted provider of medical information since 1899 SEARCH SEARCH MEDICAL TOPICS Common Health Topics Resources QUIZZES & CASES (...) cardiovascular health in women, according to a study presented at the... 3D Model Herniated Nucleus Pulposus Video How to do the Motor Examination SOCIAL MEDIA Add to Any Platform Loading , MD, University of Pennsylvania, Division of Sleep Medicine Click here for Patient Education NOTE: This is the Professional Version. CONSUMERS: Periodic limb movement disorder (PLMD) and restless legs syndrome (RLS) are characterized by abnormal motions of and sometimes sensations in the lower or upper extremities, which

2013 Merck Manual (19th Edition)

154. Syndrome of Rapid Irregular Movements of Eyes and Limbs in Childhood (PubMed)

Syndrome of Rapid Irregular Movements of Eyes and Limbs in Childhood Electroencephalographic (E.E.G.), polyelectromyographic (poly-E.M.G.), and electro-oculographic (E.O.G.) studies were made of 16 young children and babies referred because of prolonged episodes of rapid irregular movements of eyes and limbs (R.I.M.E.L.) sometimes involving also the trunk and head. This unusual syndrome of unknown aetiology developed over a period of a few days and persisted for months or years. In the E.E.G (...) . there were only minor changes, without discharges of any kind during the episodes of involuntary movements, and during sleep the spindles were unusually fast. In the poly-E.M.G. single or multiple spikes appeared as electrical concomitants of brief myoclonic phenomena at irregular intervals and independently in the various groups of muscles examined. In the E.O.G. the frequent episodes of irregular jerky movements of the eyeballs occurred at various intervals and without rhythmicity. On clinical

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1972 British medical journal

155. Use of mental practice to improve upper-limb recovery after stroke: a systematic review

Use of mental practice to improve upper-limb recovery after stroke: a systematic review Use of mental practice to improve upper-limb recovery after stroke: a systematic review Use of mental practice to improve upper-limb recovery after stroke: a systematic review Nilsen DM, Gillen G, Gordon AM CRD summary This review assessed whether upper limb recovery following stroke was improved through mental practice of physical movements. The authors concluded that there was evidence of benefit (...) , but general conclusions were difficult to make. Limitations in the review methods and in the studies that were not acknowledged by the review authors limit the reliability of the authors’ conclusions. Authors' objectives To evaluate whether mental practice, whereby a person mentally rehearses a physical skill using motor imagery without using overt physical movements, improves upper limb recovery following stroke. Searching An electronic search of PubMed, The Cochrane Library, PsycINFO and CINAHL

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2010 DARE.

156. Do lycra garments improve function and movement in children with cerebral palsy?

quadriplegia). 2 were new to wearing splints and 2 had worn splint for more than 12 months. Lycra splints for upper limb worn for up to 6.5 h/day Case series (level 4) Melbourne Assessment (upper limb). Assessed at baseline and intervention phase twice weekly. Data collection period ranged from 14 to 17 weeks No change in quality of unilateral upper limb movement. 1 Patient had a decrease in movement with long-term use Within-patient trends were analysed. Study lacked large homogeneous group of subjects (...) ). References Blair E, Ballantyne J, Horsman S, et al. A study of a dynamic proximal stability splint in the management of children with cerebral palsy. Dev Med Child Neurol 1995;37:544–54. Edmondson J, Fisher K, Hanson C. How effective are lycra suits in the management of children with cerebral palsy? J Assoc Paediatr Chart Physiotherapists 1999;90:49–57. Nicholson JH, Morton RE, Attfield S, et al. Assessment of upper-limb function and movement in children with cerebral palsy wearing lycra garments. Dev

2010 BestBETS

157. Nocturnal Hypoxemia and Periodic Limb Movement Predict Mortality in Patients on Maintenance Hemodialysis. (PubMed)

Nocturnal Hypoxemia and Periodic Limb Movement Predict Mortality in Patients on Maintenance Hemodialysis. Sleep disorders, including sleep-disordered breathing and periodic limb movements during sleep, are associated with an increased risk for cardiovascular diseases, which are the leading causes of death in patients with ESRD. This study investigated the association between sleep disorders and mortality in patients with ESRD.Thirty patients on maintenance hemodialysis, who were clinically (...) stable for >2 months, underwent overnight polysomnography to evaluate sleep parameters.All patients were followed for a median of 48 months (range: 14 to 62 months), and 14 of them died during the follow-up period. Among the sleep parameters, the percent of sleep time with arterial oxygen saturation <90% (T <90%), mean arterial oxygen saturation, and periodic limb movement index score were associated with significant increases in the risk of death. However, associations of the apnea-hypopnea index

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2010 Clinical Journal of the American Society of Nephrology

158. Visual tuning and metrical perception of realistic point-light dance movements (PubMed)

the trunk bounced vertically at every beat and the limbs moved laterally at every second beat, yielding two possible metrical periodicities. In Experiment 1, participants freely identified a tempo of the movement and tapped along. While some observers only tuned to the bounce and some only to the limbs, the majority tuned to one level or the other depending on the movement tempo, which was also associated with individuals' preferred tempo. In Experiment 2, participants reproduced the tempo of leg (...) Visual tuning and metrical perception of realistic point-light dance movements Humans move to music spontaneously, and this sensorimotor coupling underlies musical rhythm perception. The present research proposed that, based on common action representation, different metrical levels as in auditory rhythms could emerge visually when observing structured dance movements. Participants watched a point-light figure performing basic steps of Swing dance cyclically in different tempi, whereby

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2016 Scientific reports

159. The cardiovascular response to passive movement is joint dependent (PubMed)

The cardiovascular response to passive movement is joint dependent The cardiovascular responses to passive limb movement (PLM) at the knee are well established, however, responses to PLM at other joints involving smaller muscle volume are unknown. To compare the cardiovascular responses to passive movement at other joints, 10 participants underwent a PLM protocol in which the wrist, elbow, ankle, and knee joints were passively extended and flexed at 1 Hz for 1 min. Heart rate (HR), mean (...) arterial blood pressure (MAP), and arterial blood flow to that limb segment (BF) were measured and vascular conductance (VC) was calculated for a 30-sec baseline period and for 3-sec intervals throughout PLM protocols. PLM of the knee and elbow resulted in significant increases in BF and VC from baseline values with peak values 180% (P < 0.001) greater than baseline. PLM of the elbow resulted in significant increases in BF and VC from baseline values with peak values 109% and 115% (P < 0.001) greater

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2016 Physiological reports

160. Sensorimotor Synchronization with Different Metrical Levels of Point-Light Dance Movements (PubMed)

the trunk bounced at every beat and the limbs moved at every second beat, forming two metrical periodicities. Participants tapped synchronously to the bounce of the trunk with or without the limbs moving in the stimuli (Experiment 1), or tapped synchronously to the leg movements with or without the trunk bouncing simultaneously (Experiment 2). Results showed that, while synchronization with the bounce (lower-level pulse) was not influenced by the presence or absence of limb movements (metrical accent (...) Sensorimotor Synchronization with Different Metrical Levels of Point-Light Dance Movements Rhythm perception and synchronization have been extensively investigated in the auditory domain, as they underlie means of human communication such as music and speech. Although recent studies suggest comparable mechanisms for synchronizing with periodically moving visual objects, the extent to which it applies to ecologically relevant information, such as the rhythm of complex biological motion, remains

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2016 Frontiers in human neuroscience

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