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Periodic Limb Movement

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81. Dopamine Transporter Density Profiles in Patients With Periodic Limb Movements

Dopamine Transporter Density Profiles in Patients With Periodic Limb Movements Dopamine Transporter Density Profiles in Patients With Periodic Limb Movements - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more (...) . Dopamine Transporter Density Profiles in Patients With Periodic Limb Movements (DOPATRANSPLM) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT01365364 Recruitment Status : Completed First Posted : June 3, 2011 Last Update Posted : June 3, 2011 Sponsor: Federal University of São Paulo Collaborators

2011 Clinical Trials

82. Using motor behavior during an early critical period to restore skilled limb movement after damage to the corticospinal motor system during development (PubMed)

Using motor behavior during an early critical period to restore skilled limb movement after damage to the corticospinal motor system during development This study investigated the requirements for restoring motor function after corticospinal (CS) system damage during early postnatal development. Activity-dependent competition between the CS tracts (CSTs) of the two hemispheres is imperative for normal development. Blocking primary motor cortex (M1) activity unilaterally during a critical period (...) [postnatal week 5 (PW5) to PW7] produces permanent contralateral motor skill impairments, loss of M1 motor map, aberrant CS terminations, and decreases in CST presynaptic sites and spinal cholinergic interneuron numbers. To repair these motor systems impairments and restore function, we manipulated motor experience in three groups of cats after this CST injury produced by inactivation. One group wore a jacket restraining the limb ipsilateral to inactivation, forcing use of the contralateral, impaired

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2012 The Journal of neuroscience : the official journal of the Society for Neuroscience

83. Difference in Activity in the Supplementary Motor Area Depending on Limb Combination of Hand–Foot Coordinated Movements (PubMed)

Difference in Activity in the Supplementary Motor Area Depending on Limb Combination of Hand–Foot Coordinated Movements Periodic interlimb coordination shows lower performance when the ipsilateral hand and foot (e.g., right hand and right foot) are simultaneously moved than when the contralateral hand and foot (e.g., right hand and left foot) are simultaneously moved. The present study aimed to investigate how brain activity that is related to the dependence of hand-foot coordination on limb (...) combination, using functional magnetic imaging. Twenty-one right-handed subjects performed periodic coordinated movements of the ipsilateral or contralateral hand and foot in the same or opposite direction in the sagittal plane. Kinematic data showed that performance was lower for the ipsilateral hand-foot coordination than for the contralateral one. A comparison of brain activity between the same and opposite directions showed that there was a greater activation of supplementary motor area

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2016 Frontiers in human neuroscience

84. Daily Repetitive Transcranial Magnetic Stimulation for Poststroke Upper Limb Paresis in the Subacute Period. (PubMed)

Daily Repetitive Transcranial Magnetic Stimulation for Poststroke Upper Limb Paresis in the Subacute Period. We conducted a randomized, double-blind, sham-controlled study to assess the efficacy in motor recovery and safety of daily repetitive transcranial magnetic stimulation (rTMS) in subacute stroke patients.Forty-one patients were randomly assigned to a real or sham stimulation group. Each patient underwent regular rehabilitation accompanied by a series of 10 daily 5-Hz rTMS (...) of the ipsilesional primary motor cortex (M1) or sham stimulation. The primary outcome was motor recovery evaluated by the Brunnstrom stages (BS). The secondary outcomes were improvement in the Fugl-Meyer Assessment (FMA), grip power, National Institutes of Health Stroke Scale (NIHSS), Functional Independence Measure (FIM), a quantitative measurement of finger tapping movement, and the incidence of adverse events.Thirty-nine patients completed the study and were included in the analyses. The real rTMS group

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2016 Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association Controlled trial quality: predicted high

85. Neuromodulation and Synaptic Plasticity for the Control of Fast Periodic Movement: Energy Efficiency in Coupled Compliant Joints via PCA (PubMed)

Neuromodulation and Synaptic Plasticity for the Control of Fast Periodic Movement: Energy Efficiency in Coupled Compliant Joints via PCA There are multiple indications that the nervous system of animals tunes muscle output to exploit natural dynamics of the elastic locomotor system and the environment. This is an advantageous strategy especially in fast periodic movements, since the elastic elements store energy and increase energy efficiency and movement speed. Experimental evidence suggests (...) that coordination among joints involves proprioceptive input and neuromodulatory influence originating in the brain stem. However, the neural strategies underlying the coordination of fast periodic movements remain poorly understood. Based on robotics control theory, we suggest that the nervous system implements a mechanism to accomplish coordination between joints by a linear coordinate transformation from the multi-dimensional space representing proprioceptive input at the joint level into a one-dimensional

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2016 Frontiers in neurorobotics

86. EFNS guidelines on management of restless legs syndrome and periodic limb movement disorder in sleep.

EFNS guidelines on management of restless legs syndrome and periodic limb movement disorder in sleep. Guidelines and Measures | Agency for Healthcare Research & Quality HHS.gov Search ahrq.gov Search ahrq.gov Menu Topics A - Z Healthcare Delivery Latest available findings on quality of and access to health care Searchable database of AHRQ Grants, Working Papers & HHS Recovery Act Projects AHRQ Projects funded by the Patient-Centered Outcomes Research Trust Fund You are here Guidelines

2008 European Federation of Neurological Societies

87. The effects of a modified spinal mobilisation with leg movement (SMWLM) technique on sympathetic outflow to the lower limbs. (PubMed)

The effects of a modified spinal mobilisation with leg movement (SMWLM) technique on sympathetic outflow to the lower limbs. Physiotherapy management of lumbar disorders, based on Mulligan's mobilization techniques, is a treatment of choice by many physiotherapists, however, there is only limited evidence of any neurophysiological effects and much of this has focused on the cervical spine and upper limbs. This study aims to extend the knowledge base underpinning the use of a modified Mulligan's (...) spinal mobilisation with leg movement technique (SMWLM) by exploring its effects on the peripheral sympathetic nervous system (SNS) of the lower limbs. Using a single blind, placebo controlled, independent groups study design, 45 normal naive healthy males were randomly assigned to one of three experimental groups (control, placebo or treatment; SMWLM). SNS activity was determined by recording skin conductance (SC) obtained from lower limb electrodes connected to a BioPac unit. Validation

2014 Manual therapy Controlled trial quality: uncertain

88. Effects of combination of whey protein intake and rehabilitation on muscle strength and daily movements in patients with hip fracture in the early postoperative period. (PubMed)

Effects of combination of whey protein intake and rehabilitation on muscle strength and daily movements in patients with hip fracture in the early postoperative period. Elderly patients can be at risk of protein catabolism and malnutrition in the early postoperative period. Whey protein includes most essential amino acids and stimulates the synthesis of muscle protein. The purpose of this study was to investigate the effect of resistance training in combination with whey protein intake (...) intake and rehabilitation for two weeks in the early postoperative period has a beneficial effect on knee extension strength in both lower limbs and BI (transfer, walking and toilet use) scores in patients with hip fracture.Copyright © 2015 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism. All rights reserved.

2015 Clinical nutrition (Edinburgh, Scotland) Controlled trial quality: uncertain

89. Effect of a four-week virtual reality-based training versus conventional therapy on upper limb motor function after stroke: A multicenter parallel group randomized trial. (PubMed)

months after stroke onset were allocated either to an experimental group (virtual reality-based training) or a control group receiving conventional therapy (16x45 minutes within 4 weeks). The virtual reality-based training system replicated patients´ upper limb movements in real-time to manipulate virtual objects. Blinded assessors tested patients twice before, once during, and twice after the intervention up to 2-month follow-up for dexterity (primary outcome: Box and Block Test), bimanual upper (...) Effect of a four-week virtual reality-based training versus conventional therapy on upper limb motor function after stroke: A multicenter parallel group randomized trial. Virtual reality-based training has found increasing use in neurorehabilitation to improve upper limb training and facilitate motor recovery.The aim of this study was to directly compare virtual reality-based training with conventional therapy.In a multi-center, parallel-group randomized controlled trial, patients at least 6

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2018 PLoS ONE Controlled trial quality: predicted high

90. Best Practice Guidelines for Mental Health Disorders in the Perinatal Period

Best Practice Guidelines for Mental Health Disorders in the Perinatal Period Best Practice Guidelines for Mental Health Disorders in the Perinatal Period BC Reproductive Mental Health Program & Perinatal Services BC March 2014BEST PRACTICE GUIDELINES FOR MENTAL HEALTH DISORDERS IN THE PERINATAL PERIOD (2014) is a manual for healthcare clinicians who care for women during their reproductive years. This guidance describes best practices for the care of women with depression, anxiety disorders (...) , bipolar disorder and psychotic disorders, including postpartum psychosis, in the perinatal period (conception through to one year postpartum). PRODUCED BY BC Reproductive Mental Health Program, part of BC Mental Health and Substance Use Services and Perinatal Services BC. Both are agencies of the Provincial Health Services Authority in BC. In partnership with the BC Ministry of Health, Healthy Development and Women’s Health: Population and Public Health. PROJECT LEAD & MAJOR AUTHOR Janet Williams BSN

2014 British Columbia Perinatal Health Program

91. Current therapy for the upper limb after stroke: a cross-sectional survey of UK therapists. (PubMed)

and social networks to UK-based therapists.Respondents were occupational or physiotherapists currently working clinically in the UK with people after stroke. Over the 6 week data collection period, 156 respondents opened the survey, and 154 completed it. Respondents comprised 85 physiotherapists and 69 occupational therapists.Respondents reported treating the upper limb a median of three times a week (range: 1 to 7) for a mean of 29 min (SD: 18). Most (n=110) stated this was supplemented (...) deficits after stroke and a detailed template to inform standard therapy interventions in future research. Several evidence-based therapies were reported to be used by respondents (eg, constraint induced movement therapy), but others were not (eg, mental imagery). The findings also highlight that the current reported provision of upper limb therapy is markedly less than what is likely to be effective. This underlines an urgent need to configure and fund services to empower therapists to deliver greater

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2019 BMJ open

92. Fu's subcutaneous needling and constraint-induced movement therapy for a patient with chronic stroke: One-year follow-up case report. (PubMed)

A injection.A 35-year-old male experienced arm paresis after an infarction in the right posterior limb of the internal capsule 1 year before the intervention.The BTX type A injection did not work, so the patient received Fu's subcutaneous needling as an alternative therapy before 5 h of constraint-induced movement therapy for 12 weekdays.All outcome measures (Modified Ashworth Scale, Fugl-Meyer Assessment, Action Research Arm Test, and Motor Activity Log) substantially improved over the 1-year period (...) paresis.The patient suffered an infarction in the right posterior limb of the internal capsule 1 year ago, which resulted in hemiparesis in his left (nondominant) hand and arm. The only limitation for constraint-induced movement therapy was insufficient finger extension. The patient was unable to voluntarily extend his interphalangeal or metacarpophalangeal joints beyond the 10 degrees required for constraint-induced movement therapy. However, his muscle tension did not change after the BTX type

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2019 Medicine

93. Prevalence of restless legs syndrome in functional movement disorders: a case-control study from the Czech Republic. (PubMed)

and General University Hospital in Prague, Czech Republic.96 consecutive patients with clinically established FMD (80 females, mean age (SD) 45.0 (13) years), and 76 matched controls.The primary outcome measure was prevalence of RLS based on updated International RLS Study Group criteria. Secondary outcome measures included prevalence of periodic limb movements (PLM) using actigraphy; pain, motor and sensory symptoms in lower limbs; organic comorbidities and medication affecting RLS.RLS criteria were (...) Prevalence of restless legs syndrome in functional movement disorders: a case-control study from the Czech Republic. The prevalence of restless legs syndrome (RLS) in functional movement disorders (FMD) is not known. Patients with FMD often present with multiple motor and sensory symptoms. Some of these symptoms might be due to comorbid RLS. Therefore, our objective was to evaluate possible association between FMD and RLS.Case-control study.Movement Disorders Center, 1st Faculty of Medicine

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2019 BMJ open

94. Exploiting cervicolumbar connections enhances short-term spinal cord plasticity induced by rhythmic movement. (PubMed)

Exploiting cervicolumbar connections enhances short-term spinal cord plasticity induced by rhythmic movement. Arm cycling causes suppression of soleus (SOL) Hoffmann (H-) reflex that outlasts the activity period. Arm cycling presumably activates propriospinal networks that modulate Ia presynaptic inhibition. Interlimb pathways are thought to relate to the control of quadrupedal locomotion, allowing for smooth, coordinated movement of the arms and legs. We examined whether the number of active (...) limb pairs affects the amount and duration of activity-dependent plasticity of the SOL H-reflex. On separate days, 14 participants completed 4 randomly ordered 30 min experimental sessions: (1) quiet sitting (CTRL); (2) arm cycling (ARM); (3) leg cycling (LEG); and (4) arm and leg cycling (A&L) on an ergometer. SOL H-reflex and M-wave were evoked via electrical stimulation of the tibial nerve. M-wave and H-reflex recruitment curves were recorded, while the participants sat quietly prior to, 10

2019 Experimental Brain Research Controlled trial quality: uncertain

95. Non-invasive monitoring of stress biomarkers in the newborn period. (PubMed)

Non-invasive monitoring of stress biomarkers in the newborn period. The neonatal period is a highly sensitive time span during which stressful experiences may have an influence on later health outcomes. Medical procedures applied to newborn babies during hospitalization are stressors that trigger a physiological and psychological stress response. Stress response has been traditionally evaluated using scores based on behavioural signs such as facial expressions, limb movements, crying, etc (...) ., which are subjectively interpreted. Only few studies have employed measurable physiological signs to objectively evaluate the stress response to specific interventions. The aim of this review is to inform of recently developed biochemical methods that allow clinicians to evaluate the stress response to medical procedures performed in the neonatal period in biological samples non-invasively obtained. Stress biomarkers are based on the physiological stress response mediated by the hypophysis-pituitary

2019 Seminars in fetal & neonatal medicine

96. Robot-assisted therapy for long-term upper limb impairment after stroke

; the Robotic Rehabilitation System for upper limb motion therapy; the Neuro-Rehabilitation-Robot (NeRoBot); the Bi-Manu-Track; the robot-mediated therapy system GENTLE/S; and the Arm robot, ARMin (Mehrholz et al 2009). All of these systems aim to provide treatment for the recovery of movement and strength of limbs, specifically the upper limbs. The technology would be made available through specialised rehabilitation 2 Robot-assisted therapy for upper limb impairment after stroke: November 2010 centres (...) the assistance or increasing the resistance given by the device Robot-assisted therapy for upper limb impairment after stroke: November 2010 3 and by altering the movement amplitude. In addition, some devices such as the Bi- Manu-Track move the affected limb passively, steered by the non-paretic limb in a therapy called “mirroring” (Figure 1). Most robotic systems would incorporate more than one modality (Mehrholz et al 2009). Figure 1 A patient using the Bi-Manu-Track device (Reha-Stim 2009) The National

2011 Australia and New Zealand Horizon Scanning Network

97. Impact of dairy protein during limb immobilization and recovery on muscle size and protein synthesis; a randomized controlled trial. (PubMed)

Impact of dairy protein during limb immobilization and recovery on muscle size and protein synthesis; a randomized controlled trial. Muscle disuse results in the loss of muscular strength and size, due to an imbalance between protein synthesis (MPS) and breakdown (MPB). Protein ingestion stimulates MPS, although it is not established if protein is able to attenuate muscle loss with immobilization (IM) or influence the recovery consisting of ambulatory movement followed by resistance training (...) Twenty grams of daily protein supplementation does not attenuate the loss of muscle size and function induced by 2 wk of muscle disuse or potentiate recovery in middle-age men. Average mitochondrial but not myofibrillar muscle protein synthesis was attenuated during immobilization with no effect of supplementation. Protein supplementation increased myofibrillar protein synthesis during a 2-wk period of ambulatory recovery following disuse but without group differences in phenotype recovery.

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2018 Journal of applied physiology (Bethesda, Md. : 1985) Controlled trial quality: uncertain

98. Synergistic Bilateral Upper-Limb Stroke Rehabilitation Based on Robotic Priming Technique

Synergistic Bilateral Upper-Limb Stroke Rehabilitation Based on Robotic Priming Technique Synergistic Bilateral Upper-Limb Stroke Rehabilitation Based on Robotic Priming Technique - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more (...) studies before adding more. Synergistic Bilateral Upper-Limb Stroke Rehabilitation Based on Robotic Priming Technique The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT03773653 Recruitment Status : Recruiting First Posted

2018 Clinical Trials

99. Clinical Trial of the Virtual Integration Environment to Treat Phantom Limb Pain With Upper Extremity Amputation (PubMed)

as a therapy device to effectively treat PLP in individuals with UE amputation. Methods: Participants with UE amputation and PLP were recruited at Walter Reed National Military Medical Center (WRNMMC) and instructed to follow the limb movements of a virtual avatar within the VIE system across a series of study sessions. At the end of each session, participants drove virtual avatar limb movements during a period of "free-play" utilizing surface electromyography recordings collected from their residual limbs (...) Clinical Trial of the Virtual Integration Environment to Treat Phantom Limb Pain With Upper Extremity Amputation Background: Phantom limb pain (PLP) is commonly seen following upper extremity (UE) amputation. Use of both mirror therapy, which utilizes limb reflection in a mirror, and virtual reality therapy, which utilizes computer limb simulation, has been used to relieve PLP. We explored whether the Virtual Integration Environment (VIE), a virtual reality UE simulator, could be used

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2018 Frontiers in neurology

100. A Narrative Review on Avulsion Fractures of the Upper and Lower Limbs (PubMed)

A Narrative Review on Avulsion Fractures of the Upper and Lower Limbs Avulsion fractures compromise function and movement at the affected joint. If left untreated, it can lead to deformity, nonunion, malunion, pain, and disability. The purpose of this review was to identify and describe the epidemiology and available treatment options for common avulsion fractures of the upper and lower extremities. Current evidence suggests that optimal treatment is dependent on the severity of the fracture (...) . Conservative efforts generally include casting or splinting with a period of immobilization. Surgery is typically indicated for more severe cases or if nonoperative treatments fail; patient demographics or preferences and surgeon experience may also play a role in decision making. Some avulsion fractures can be surgically managed with any one of various techniques, each with their own pros and cons, and often there is no clear consensus on choosing one technique over another; however, there is some

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2018 Clinical medicine insights. Arthritis and musculoskeletal disorders

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