How to Trip Rapid Review

Step 1: Select articles relevant to your search (remember the system is only optimised for single intervention studies)

Step 2: press

Step 3: review the result, and maybe amend the or if you know better! If we're unsure of the overall sentiment of the trial we will display the conclusion under the article title. We then require you to tell us what the correct sentiment is.

3,181 results for

Periodic Limb Movement

by
...
Latest & greatest
Alerts

Export results

Use check boxes to select individual results below

SmartSearch available

Trip's SmartSearch engine has discovered connected searches & results. Click to show

3101. Efficacy of diclofenac in lateral epicondylitis of the elbow also treated with immobilization. The University of Montreal Orthopaedic Research Group. (Abstract)

21 days.The experimental group was treated with a daily dose of diclofenac sodium (150 mg) for 28 days, while the control group received a placebo during the same period. In addition, both groups were immobilized in a cast for 14 days and were told not to perform repetitive movements of the involved limb for 21 days.Measuring instruments consisted of grip strength measurements with a squeeze dynamometer, a visual analog pain scale, a visual analog function scale, and an 8-item pain-free function (...) of lateral epicondylitis beyond and over rest in an experimental group compared with a control group after 4 weeks of treatment.Recruitment from urban general practices and referrals to 4 university hospitals.During a 1-year period, 206 subjects aged 18 to 60 years with lateral epicondylitis were recruited from the clientele treated by family physicians. Thirty subjects refused to participate and 47 presented with exclusion criteria, leaving 129 subjects who entered the study. One subject withdrew after

1997 Archives of family medicine Controlled trial quality: predicted high

3102. Open-label trial of oral nalmefene therapy for the pruritus of cholestasis. Full Text available with Trip Pro

of limb movements, was recorded continuously for 24-hour periods before and during treatment with an initial ameliorating dose of nalmefene. Simultaneously, during these periods, visual analogue scores (VASs) of pruritus were recorded every 4 hours while patients were awake. The dose of nalmefene, which initially was 2 mg orally twice daily, was increased during the study, usually until a satisfactory clinical response was achieved. Five patients experienced a transient opioid withdrawal-like reaction

1998 Hepatology

3103. Evaluating the role of botulinum toxin in the management of focal hypertonia in adults. Full Text available with Trip Pro

of symptoms 35 months (range 3 months to 22 years). Diagnoses included cerebrovascular accidents (23), head injury (12), incomplete spinal cord injury (six), tumour (five), cerebral palsy (three), and anoxic episodes (three).For each variable an overall score for the treatment period was computed by summing the scores from the 3, 6, 9, and 12 week assessments. These overall scores were significantly better in the treated group for the Ashworth scale, percentage passive range of movement, Rivermead lower (...) limb, and subjective rating of problem severity. The significant treatment effect on the Ashworth scale was seen on analysis of variance (ANOVA) at 3 weeks and the subjective rating of problem severity at 3 and 6 weeks. The goal attainment scale score in both groups was similar at 12 weeks.Selective use of botulinum toxin to weaken muscles can lead to a reduction in resistance to passive movement about a distal limb joint. This allows for improvements in passive range of movement and focal

2000 Journal of neurology, neurosurgery, and psychiatry Controlled trial quality: uncertain

3104. Randomized, double-blind, placebo-controlled trial of pergolide in restless legs syndrome. (Abstract)

of treatment (days 17 and 18).As a group, pergolide recipients showed significant improvement clinically and statistically in all outcome measures when compared with baseline or with placebo treatment. On the other hand, placebo treatment led to no significant improvements in any outcome measures.Pergolide treatment significantly improved clinical symptoms and sleep efficiency, and reduced periodic limb movements of sleep in patients with RLS. (...) schedule that ranged from 0.05 to 0.65 mg/day. Outcome variables included the patient's rating of symptom improvement, duration of RLS symptoms throughout the day, and objective sleep assessments from an all-night polysomnogram (percent sleep efficiency and periodic leg movements). Baseline was assessed for 2 days before starting treatment. Dose adjustments were made over the first 14 days and were then held constant for 5 days, with repeat assessment for treatment effects on the last 2 days

1998 Neurology Controlled trial quality: predicted high

3105. Laryngeal mask insertion during target-controlled infusion of propofol. (Abstract)

conditions (mouth opening, gagging, coughing, head or limb movement, laryngospasm, overall ease of insertion) were assessed, and hemodynamic responses were evaluated until 3 minutes after LMA insertion. Total dose of propofol, EC, and elapsed time since the start of TCI were recorded at five times: at the loss of consciousness and eyelash reflex, at 2.5 microg/mL of EC, and immediately, 1 minute, and 3 minutes after the insertion of LMA.There was no significant difference between the two groups (...) in insertion conditions, despite the significantly larger total dose and shorter elapsed time (2.6 +/- 0.08 mg/kg and 109 +/- 5.0 s) in Group 2 than those (2.1 +/- 0.02 mg/kg and 140 +/- 4.1 s) in Group 1 at 2.5 microg/mL of EC (p < 0.05). Systolic and diastolic blood pressure decreased and heart rate increased significantly throughout the study period in both groups (p < 0.05). But there was a significant decrease in arterial pressure in Group 2 compared with Group 1 1 and 3 minutes after the insertion (p

2001 Journal of clinical anesthesia Controlled trial quality: uncertain

3106. A new design of a polysomnography-based multi-center treatment study for the restless legs syndrome. (Abstract)

A new design of a polysomnography-based multi-center treatment study for the restless legs syndrome. Periodic limb movements (PLM) cause sleep disorders and daytime symptoms and are frequently associated with restless legs syndrome (RLS). Treatment of RLS with increased PLM during sleep (PLMS) has been evaluated in studies limited in size, methodology and study length. This long-term, placebo-controlled, multi-center, study with polysomnography (PSG) recordings has been designed in order

2002 Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology Controlled trial quality: uncertain

3107. Influence of supervised and nonsupervised training on postural control after an acute anterior cruciate ligament rupture: a three-year longitudinal prospective study. (Abstract)

of pressure movements) and a one-leg hop test for distance after 6 weeks (stabilometry only), and after 3, 12, and 36 months, and were compared to a control group.Regardless of treatment, center of pressure amplitude was persistently higher in both the injured and uninjured legs during the 3-year follow-up, but average speed was less affected or unaffected compared to the control group. The one-leg hop had normalized in the neuromuscular group at the 12-month follow-up, but was shorter in both legs (...) throughout the 3-year period in the self-monitored group. The median value (quartiles) for injured/uninjured legs at 3 months was 150 cm (120-174 cm)/177 cm (140-199 cm), at 12 months was 174 cm (140-200 cm)/180 cm (150-202 cm), and at 36 months was 172 cm (146-200 cm)/178 cm (150-200 cm) in the self-monitored group, compared to the control group (median 186 cm, quartiles 177-216 cm).The higher center of pressure amplitude in both legs over the 3-year period indicate persistently impaired postural

2001 The Journal of orthopaedic and sports physical therapy Controlled trial quality: uncertain

3108. [Rapid sequence intubation in emergency: is there any place for fentanyl?]. (Abstract)

signs arrival (respiratory movements, eyes opening, spontaneous limb movements), Ramsay score assessment, and haemody namics. Attempt at intubation and vomiting incident were also measured. Discrete data were compared by chi-2 analysis, continuous data were compared with two-way analysis of variance. A p value < 0.05 was the significant threshold.Thirty-six patients were enrolled and completed the study. All the included patients presented awakening signs. The use of fentanyl did not prevent (...) [Rapid sequence intubation in emergency: is there any place for fentanyl?]. Rapid sequence intubation (RSI) with the association of etomidate and succinylcholine is the French "Gold standard" for urgent "full stomach" endotracheal intubations. The aim of this study is to assess the fentanyl as a co-induction agent to take over the sedation between the RSI and the keeping of sedation, which is a critical period in which harmful neuro-vegetatives events, and awakening signs are frequently

2002 Annales francaises d'anesthesie et de reanimation Controlled trial quality: uncertain

3109. Reproducibility of the measurement of the muscle ergoreflex activity in chronic heart failure. (Abstract)

-min submaximal handgrip and leg exercises. On one run the subjects recovered normally (control recovery), while on the other a post-exercise regional circulatory occlusion (PE-RCO) was induced in the exercising limb, to isolate the stimulation of the metaboreceptor after exercise. The metaboreflex was quantified as the difference in ventilation between the PE-RCO and the control recovery periods with respect to rest. The existence of a mechanoreflex was sought by comparing the ventilatory (...) increment per unit of active work (dV(E)/dVO(2) ratio) between leg passive movement and active low level exercise. The coefficients of variation (CV) were computed to express the reproducibility of these reflexes in heart failure.The metaboreflex was overactive in patients vs. normals during both arm (7.2+/-2.8 l/min vs. 0.06+/-0.3 l/min) and leg (5.6+/-1.2 l/min vs. 0.5+/-0.2 l/min) tests. The mechanoreflex was not different between patients and normals: dV(E)/dVO(2) during passive movement 48.9+/-18.3

2003 European journal of heart failure Controlled trial quality: uncertain

3110. When should patients begin ambulating following lower limb split skin graft surgery: a systematic review

% in between 67 and 100% of patients (seven studies) after varying periods of time (range where reported 15 days to three weeks). Five studies investigated the effects of commencing ambulation one day after lower limb graft surgery. Two RCTs reported no difference between early and late ambulation (at five days and 10 days) in graft healing rates (one study), or mean time to graft take and hospital stay (one study that did not report statistical values). One study reported no difference in wound healing (...) When should patients begin ambulating following lower limb split skin graft surgery: a systematic review When should patients begin ambulating following lower limb split skin graft surgery: a systematic review When should patients begin ambulating following lower limb split skin graft surgery: a systematic review Smith T O CRD summary The review summarised the effects of early ambulation in patients with lower limb split skin graft surgery. The literature suggested that patients should start

2006 DARE.

3111. Botulinum neurotoxin for the treatment of movement disorders

Class II studies). While a few patients in one Class II study suggest that BoNT may be effective for lower extremity dystonia, the data are inadequate to provide a recommendation. Recommendation. BoNT should be considered as a treatment option for focal upper extremity dystonia (Level B). Clinical context. The treatment of focal limb dystonia with BoNT presents challenges, particularly in achieving sufficient neuromuscular blockade to alleviate dystonic movements without causing excessive muscle (...) were randomized to receive either 50 units of BoNT-A (Botox®) or placebo injections into the wrist flexors and extensors of the dominant limb. If patients failed to respond to the initial injection, they were eligible to receive another injection of 100 units 4 weeks later. Rest, postural, and kinetic tremor were evaluated at 2- to 4-week intervals over a 16-week study period, using tremor severity rating scales, accelerometry, and assessments of improvement and disability. There was significant

2008 American Academy of Neurology

3112. Nitric oxide is released into circulation with whole-body, periodic acceleration. Full Text available with Trip Pro

wave were obtained with a photoelectric-plethysmograph sensor.The position of the dicrotic notch from the pulse waveform was computed from the amplitude of the pulse divided by the height of the dicrotic notch above the end-diastolic level (a/b ratio). Increase of the a/b ratio reflects the vasodilator action of NO that causes downward movement of the dicrotic notch in the diastolic limb of the digital pulse, thereby elevating the a/b ratio.Application of whole-body, periodic acceleration was well (...) Nitric oxide is released into circulation with whole-body, periodic acceleration. To determine if comfortably applied, whole-body, periodic acceleration releases significant amounts of nitric oxide (NO) into the circulation of healthy subjects and patients with inflammatory diseases.Fourteen healthy adults and 40 adult patients with inflammatory diseases underwent single 45-min trials of whole-body, periodic acceleration with a new "passive exercise" device, while an ECG and a digital pulse

2005 Chest

3113. Pediatric endurance and limb strengthening for children with cerebral palsy (PEDALS)--a randomized controlled trial protocol for a stationary cycling intervention. Full Text available with Trip Pro

Pediatric endurance and limb strengthening for children with cerebral palsy (PEDALS)--a randomized controlled trial protocol for a stationary cycling intervention. In the past, effortful exercises were considered inappropriate for children with spastic cerebral palsy (CP) due to concern that they would escalate abnormalities including spasticity and abnormal movement patterns. Current scientific evidence indicates that these concerns were unfounded and that therapeutic interventions focused (...) will be recruited for this study. Participants will be randomly assigned to either an intervention (cycling) or a control (no cycling) group. The cycling intervention will be divided into strengthening and cardiorespiratory endurance exercise phases. During the strengthening phase, the resistance to lower extremity cycling will be progressively increased using a uniquely designed limb-loaded mechanism. The cardiorespiratory endurance phase will focus on increasing the intensity and duration of cycling. Children

2007 BMC pediatrics Controlled trial quality: uncertain

3114. Upper limb corticomotor projections and physiological changes that occur with botulinum toxin-A therapy in children with hemiplegic cerebral palsy. (Abstract)

and control groups, and there was no statistically significant difference between groups at 1, 3 or 6 months. Poor tolerance of TMS cortical stimuli >80% was observed.Corticomotor projections associated with the upper limb in children with hemiplegic CP show significant variability over a 6-month period. This variability may reflect central motor reorganization because of systemic BTX-A effect or developmental changes. Upper limb BTX-A therapy is associated with reorganization of both affected (...) Upper limb corticomotor projections and physiological changes that occur with botulinum toxin-A therapy in children with hemiplegic cerebral palsy. To investigate the corticomotor projection to the upper limb in children with hemiplegic cerebral palsy (CP) and the changes that occur with botulinum toxin (BTX)-A.The study design is a pilot prospective randomized trial. Twenty-two children with hemiplegic CP aged 7 years to 13 years 11 months were recruited. Treatment group (12) received one

2008 European journal of neurology : the official journal of the European Federation of Neurological Societies Controlled trial quality: uncertain

3115. Residual function in peripheral nerve stumps of amputees: implications for neural control of artificial limbs. (Abstract)

Residual function in peripheral nerve stumps of amputees: implications for neural control of artificial limbs. It is not known whether motor and sensory pathways associated with a missing or denervated limb remain functionally intact over periods of many months or years after amputation or chronic peripheral nerve transection injury. We examined the extent to which activity on chronically severed motor nerve fibers could be controlled by human amputees and whether distally referred tactile (...) was possible to record volitional motor nerve activity uniquely associated with missing limb movements. Electrical stimulation through the implanted electrodes elicited discrete, unitary, graded sensations of touch, joint movement, and position, referring to the missing limb.These findings indicate that both central and peripheral motor and somatosensory pathways retain significant residual connectivity and function for many years after limb amputation. This implies that peripheral nerve interfaces could

2004 Journal of Hand Surgery - American

3116. Lower limb strength training in children with cerebral palsy--a randomized controlled trial protocol for functional strength training based on progressive resistance exercise principles. Full Text available with Trip Pro

Lower limb strength training in children with cerebral palsy--a randomized controlled trial protocol for functional strength training based on progressive resistance exercise principles. Until recently, strength training in children with cerebral palsy (CP) was considered to be inappropriate, because it could lead to increased spasticity or abnormal movement patterns. However, the results of recent studies suggest that progressive strength training can lead to increased strength and improved (...) after, and 6 weeks after the intervention period. Primary outcomes in this study were gross motor function (measured with the Gross Motor Function Measure and functional muscle strength tests) and walking ability (measured with the 10-meter, the 1-minute and the timed stair test). Secondary outcomes were lower limb muscle strength (measured with a 6 RM test, isometric strength tests, and a sprint capacity test), mobility (measured with a mobility questionnaire), and sport activities (measured

2008 BMC pediatrics Controlled trial quality: uncertain

3117. The lowest effective dose of botulinum A toxin in adult patients with upper limb spasticity. (Abstract)

with residual voluntary movement in the upper limb appears to be 500 U. (...) The lowest effective dose of botulinum A toxin in adult patients with upper limb spasticity. To define the lowest effective dose of botulinum toxin type A (Dysport) and safety in the treatment of adult patients with upper limb spasticity.This was a prospective, randomized, double-blind, dose-ranging study. Patients received either a placebo or one of three does of Dysport (350, 500 100) U) into five muscles of affected arm by anatomical and electromyography guidance. Efficacy was assessed

2005 Disability and rehabilitation Controlled trial quality: uncertain

3118. Changes in lower limb kinematics, kinetics, and muscle activity in subjects with functional instability of the ankle joint during a single leg drop jump. (Abstract)

onto a force-plate. Timing and magnitude of kinetic data, timing of kinematic data, and integrated EMG (IEMG) activity of the rectus femoris, peroneus longus, tibialis anterior, and soleus muscles during two 200-ms time periods either side of initial contact (IC) with the ground were analyzed and compared between groups. Subjects with FI demonstrated a significant decrease in pre-IC peroneus longus IEMG activity, which was accompanied by a change in frontal plane movement at the ankle joint during (...) Changes in lower limb kinematics, kinetics, and muscle activity in subjects with functional instability of the ankle joint during a single leg drop jump. The purpose of this study was to identify differences in 3D kinematics, kinetics, and ankle joint muscle activity in subjects with functional instability (FI) of the ankle joint during a drop jump. Twenty-four subjects with the subjective complaint of FI of the ankle joint and 24 noninjured control subjects performed 10 single leg drop jumps

2006 Journal of Orthopaedic Research

3119. Poor dopaminergic response of impaired dexterity in Parkinson's disease: Bradykinesia or limb kinetic apraxia? Full Text available with Trip Pro

Poor dopaminergic response of impaired dexterity in Parkinson's disease: Bradykinesia or limb kinetic apraxia? Patients with Parkinson's disease (PD) often show impaired manual dexterity even when being only minimally bradykinetic, suggesting that they may have limb kinetic apraxia (LKA), that is, a loss of fine motor skill not explained by elemental motor deficits. To explore this dissociation, we investigated the differential dopaminergic responsiveness of dexterity and bradykinesia in PD (...) . Twelve patients with PD (4 women, age 64.4 +/- 8.3, mean + SD) and 12 matched healthy controls (64.8 +/- 8.9) were tested twice in ON vs. OFF and 1st vs. 2nd trial, respectively. A coin rotation (CR) task was applied to assess dexterity and a finger tapping (FT) task to assess bradykinesia. Performance was followed by video recording and analyzed by measuring the frequency of CR and FT during three 10-second periods. Statistical analysis was done by a mixed factorial design with group (PD vs

2008 Movement Disorders

3120. A Pilot Study of Neuro Hand Orthosis Program In Stroke Upper Limb Rehabilitation

Paralytic Stroke Other: Conventional upper limb stroke rehabilitation Device: Neuro Hand Orthosis Program (NHOP) Not Applicable Detailed Description: The neuro hand orthosis is based on a design of dynamic hand orthosis for orthopaedic patients. We attempt to apply such an orthosis on stroke patients to aid in regaining movement from severe paralytic arm by helping the patients to support their wrist and finger in a functional position for grasping. The patient is then encouraged to produce voluntary (...) Last Verified: February 2009 Keywords provided by St Luke's Hospital, Singapore: stroke upper limb rehabilitation treatment movement recovery from sever paralytic upper limb neuro hand orthosis self practice program subacute Additional relevant MeSH terms: Layout table for MeSH terms Stroke Cerebrovascular Disorders Brain Diseases Central Nervous System Diseases Nervous System Diseases Vascular Diseases Cardiovascular Diseases

2008 Clinical Trials

To help you find the content you need quickly, you can filter your results via the categories on the right-hand side >>>>