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Periodic Limb Movement

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3101. Post Stroke Hand Functions: Bilateral Movements and Electrical Stimulation Treatments

: University of Florida Information provided by (Responsible Party): University of Florida Study Details Study Description Go to Brief Summary: The purpose of this study was to determine the effect of two amounts of treatment therapy on post stroke motor recovery in the arms. The therapy is bilateral movement training combined with electrical stimulation on the impaired limb. Condition or disease Intervention/treatment Phase Cerebrovascular Accident Hemiplegia Behavioral: Bilateral movements (...) electrical stimulation triggered by the participants' own contracting muscles is provided to the paretic arm during the movements. Training period was 4 times per week for 2 weeks. Other Name: functional electrical stimulation Active Comparator: Low Intensity Bilateral training moving both arms coupled with neuromuscular electrical stimulation; two 90-minute sessions/week for 2 weeks. Behavioral: Bilateral movements and neuromuscular electrical stimulation Participants practice moving both their paretic

2006 Clinical Trials

3102. Study of Fetal Movements Using Multichannel Ultrasound Pulsed Doppler in Normal and Pathologic Pregnancy

abdomen. One of the transducers is aimed at the fetal heart, another at the lower limbs and one transducer at the thorax and the fetal upper limbs to detect heart and body movements. The signals are analysed and processed by software which computes a number of parameters describing the movements. Ninety pregnant women from 28 weeks gestation will be monitored over a 40 minute period every month or every 2 weeks in case of pathological pregnancy. The final purpose will be to develop a system of home (...) Study of Fetal Movements Using Multichannel Ultrasound Pulsed Doppler in Normal and Pathologic Pregnancy Study of Fetal Movements Using Multichannel Ultrasound Pulsed Doppler in Normal and Pathologic Pregnancy - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100

2005 Clinical Trials

3103. Early effects of embryonic movement: ‘a shot out of the dark’ Full Text available with Trip Pro

by developing novel models and schemes to examine the influence of defined periods of movement during musculoskeletal development. Utilizing drugs with known neuromuscular actions to provoke hyperactivity (4-aminopyridine, AP) and either rigid (decamethonium bromide, DMB) or flaccid (pancuronium bromide, PB) paralysis, we have examined the role of movement in joint, osteochondral and muscle development. Our initial studies focusing on the joint showed that AP-induced hyperactivity had little, if any, effect (...) , with different developmental periods preferentially modifying specific osteochondral components. Changes in cartilage and bone growth induced by 3-day periods of flaccid immobilization, imposed at distinct developmental phases, provides support for a diminution in cartilage elaboration at an early phase and for a relatively delayed influence of movement on osteogenesis, invoking critical periods during which the developing skeleton becomes receptive to the impact of movement. Immobilization also exerts

2006 Journal of anatomy

3104. A randomized controlled trial of modified constraint-induced movement therapy for elderly stroke survivors: changes in motor impairment, daily functioning, and quality of life. (Abstract)

patients (mean age, 72 y) with 0.5 to 31 months postonset of a first-ever cerebrovascular accident.Twenty-six patients received either mCIMT (restraint of the unaffected limb combined with intensive training of the affected limb) or traditional rehabilitation for a period of 3 weeks.Outcome measures included the Fugl-Meyer Assessment (FMA), FIM instrument, Motor Activity Log (MAL), and Stroke Impact Scale (SIS). The FMA evaluated the severity of motor impairment; the FIM instrument and MAL reported (...) A randomized controlled trial of modified constraint-induced movement therapy for elderly stroke survivors: changes in motor impairment, daily functioning, and quality of life. To examine the benefits of modified constraint-induced movement therapy (mCIMT) on motor function, daily function, and health-related quality of life (HRQOL) in elderly stroke survivors.Two-group randomized controlled trial, with pretreatment and posttreatment measures.Rehabilitation clinics.Twenty-six elderly stroke

2007 Archives of physical medicine and rehabilitation Controlled trial quality: uncertain

3105. Constraint-induced movement therapy in patients with stroke: a pilot study on effects of small group training and of extended mitt use. (Abstract)

Constraint-induced movement therapy in patients with stroke: a pilot study on effects of small group training and of extended mitt use. (1) To evaluate constraint-induced movement therapy for chronic stroke patients modified into group practice to limit the demand on therapist resources. (2) To explore whether extended mitt use alone may enhance outcome.A combined case-control and randomized controlled study with pre- and post-treatment measures by blinded observers.A university hospital (...) rehabilitation department.Sixteen stroke patients (nine men and seven women; mean age 56.7 years; on average 28.9 months post stroke, five of whom were 6-9 months post stroke) with moderate motor impairments in the contralateral upper limb.Constraint-induced therapy (mitt on the less affected hand 90% of waking hours for 12 days) with 2-3 patients per therapist and 6 h of group training per day. After the training period, the patients were randomized either to using the mitt at home every other day for two

2006 Clinical rehabilitation Controlled trial quality: predicted high

3106. Efficacy of a child-friendly form of constraint-induced movement therapy in hemiplegic cerebral palsy: a randomized control trial. (Abstract)

extremity, which were sustained through the 6-month evaluation period, as measured by the Jebsen-Taylor Test of Hand Function and fine motor-subtests of the Bruininks-Oseretsky Test of Motor Proficiency (p<0.05 in both cases). Initial severity of hand impairment and testing compliance were strong predictors of improvement. Caregivers reported significant increases in involved limb frequency of use and quality of movement. However, there was no change in strength, sensibility, or muscle tone (p>0.05 (...) Efficacy of a child-friendly form of constraint-induced movement therapy in hemiplegic cerebral palsy: a randomized control trial. Constraint-induced (CI) movement therapy is a promising therapy for improving upper limb function in adults after stroke. It involves restraint of the non-involved limb and extensive movement practice with the involved limb. In this study, a single-blinded, randomized, control study was performed to examine the efficacy of CI therapy, modified to be child friendly

2006 Developmental Medicine and Child Neurology Controlled trial quality: uncertain

3107. Changes in spastic muscle tone increase in patients with spinal cord injury using functional electrical stimulation and passive leg movements. (Abstract)

Changes in spastic muscle tone increase in patients with spinal cord injury using functional electrical stimulation and passive leg movements. Comparison of cycling interventions to reduce spastic muscle tone increase in patients with spinal cord injury.Neuroprosthetic outpatient clinic in a university hospital.Five patients with spinal cord injury took part in a crossover study in which the lower limbs (1) were stimulated by functional neuromuscular electrical stimulation (FES) to induce leg (...) cycling movements and (2) were passively moved by an ergometer machine. Patients sat in a comfortable chair fastened to the ergometer while FES was done to induce leg cycling (active session). During the passive leg movement session the ergometer moved their legs for the same period of time at the same velocity and frequency.The change in spastic muscle tone increase before and after each training session was tested with the modified Ashworth Scale and the pendulum test of spasticity (relaxation index

2008 Clinical rehabilitation Controlled trial quality: uncertain

3108. The distinctive movement disorder of ovarian teratoma-associated encephalitis. (Abstract)

The distinctive movement disorder of ovarian teratoma-associated encephalitis. The movement disorder observed in four cases of ovarian teratoma associated encephalitis is described. The illness began with neuropsychiatric symptoms and was followed by prolonged unresponsiveness, respiratory failure, and autonomic instability. The movement disorder consisted of semirhythmic repetitive bulbar and limb movements and persisted during prolonged periods of unresponsiveness, diminishing as awareness (...) returned. The characteristics of the movement disorder differed from recognized dyskinesias. It is suggested that interruption of forebrain corticostriatal inputs by anti-N-methyl-D-aspartate (NMDA) receptor antibodies removes tonic inhibition of brainstem pattern generators releasing primitive patterns of bulbar and limb movement. Recognition of the distinctive movements should prompt a search for an ovarian teratoma since the condition is responsive to tumor resection and immunomodulation.(c) 2008

2008 Movement Disorders

3109. Measurement of pruritus in a Chinese woman with pemphigoid gestationis using a wrist movement detector. (Abstract)

Measurement of pruritus in a Chinese woman with pemphigoid gestationis using a wrist movement detector. Pemphigoid gestationis (PG) is a rare itching bullous disease of pregnancy and the postpartum period. We describe the use of a new methodology for measuring the nature and intensity of itching in a 21-year-old woman with pemphigoid gestationis. At 19 weeks gestation, she developed an itchy rash over the limbs, which spread to the trunk. Blisters then appeared on the hands which subsequently (...) also involved the feet. Intense nocturnal wrist activities in this patient, measured with a wrist monitor and defined as average acceleration in the early hours of sleep, were even higher than that in patients with severe eczema, with an average value of 181.00 +/- 43.49 (mean +/- standard error) g/min for the first three hours, versus 84.47 +/- 8.53 g/min for the group of 24 eczema subjects. Most wrist activities were slower movements at 0 to 1 Hz. This is in striking contrast to the scratching

2008 International Journal of Dermatology

3110. Angle stable locking reduces interfragmentary movements and promotes healing after unreamed nailing. Study of a displaced osteotomy model in sheep tibiae. (Abstract)

. Each pair of tibiae was also mechanically tested until torsional failure, after which the whole callus region was subjected to histological and histomorphometric analysis.Throughout the examination period, the interfragmentary movements in all directions were significantly smaller in the group treated with the angle stable tibial nail than they were in the group treated with standard unreamed tibial nailing. The limbs treated with the angle stable tibial nails returned to almost full weight-bearing (...) during the period of the investigation, whereas those treated with standard nailing did not. Histomorphometric analysis, radiographic data, and mechanical testing showed superior bone-healing following treatment with the angle stable tibial nail.Use of an angle stable tibial nail may help to reduce interfragmentary movements in vivo and thus lead to superior bone-healing compared with that following standard unreamed tibial nailing.

2005 The Journal of Bone and Joint Surgery. American Volume

3111. Movement disorders associated with complex regional pain syndrome in children. Full Text available with Trip Pro

Movement disorders associated with complex regional pain syndrome in children. The aim of the present study was to review the history, clinical course, treatment, and outcome of movement disorders in children and young people with complex regional pain syndrome (CRPS). Case notes were reviewed retrospectively of children and young people who presented with movement disorders in CRPS to our tertiary paediatric pain service over a period of 13 years. Ten children with CRPS presented with movement (...) disorders (eight females, two males). The age at first presentation with symptoms of CRPS ranged from 8 to 15 years (mean 11 y 2 mo, median 13 y). The most common movement disorder was dystonia (n=8), followed by tremors (n=3) and myoclonus (n=3); two patients had all three movement disorders. The movement disorder affected mainly the lower limb (n=9) with a predilection for the foot (n=7) and was frequently initiated by minor trauma (n=7). Follow-up ranged from 6 months to 14 years. The outcome

2008 Developmental Medicine and Child Neurology

3112. EFNS guidelines on management of restless legs syndrome and periodic limb movement disorder in sleep Full Text available with Trip Pro

EFNS guidelines on management of restless legs syndrome and periodic limb movement disorder in sleep EFNS guidelines on management of restless legs syndrome and periodic limb movement disorder in sleep EFNS guidelines on management of restless legs syndrome and periodic limb movement disorder in sleep Vignatelli L, Billiard M, Clarenbach P, Garcia-Borreguero D, Kaynak D, Liesiene V, Trenkwalder C, Montagna P CRD summary The authors concluded that level A recommendations support the use (...) of cabergoline, gabapentin, pergolide, ropinirole, and short-term levodopa and transdermal rotigotine for primary restless leg syndrome. The evidence appears to support the authors’ conclusions, but the poor reporting of review methods makes it difficult to comment on the reliability of these conclusions. Authors' objectives To evaluate the effectiveness of treatments for restless leg syndrome (RLS) and periodic limb movement disorder (PLMD) in sleep. Searching MEDLINE, EMBASE, CINAHL and the Cochrane

2006 DARE.

3113. Abnormal Involuntary Movements

, hands, toes and feet. The arms, legs, neck and tongue may also be affected. Causes include asphyxia, neonatal jaundice, Huntington's chorea, cerebrovascular disease and trauma. Management can be difficult but treatment options include medications (eg, diazepam, haloperidol, tetrabenazine), surgery and retraining techniques. Chorea Continuous jerky movements in which each movement is sudden and the resulting posture is held for a few seconds. This usually affects the head, face or limbs. The focus (...) . [ ] There are three types of pathological tremor: Static - occurs in a relaxed limb when fully supported at rest. Causes include Parkinson's disease, Parkinsonism, other extrapyramidal diseases, multiple sclerosis. Postural - occurs if a limb is static (can also remain during movement). Types include physiological tremor, exaggerated physiological tremor - eg, in thyrotoxicosis, anxiety states, alcohol abuse, drugs (eg, sympathomimetics, antidepressants, valproate, lithium), heavy metal poisoning ('hatter's

2008 Mentor

3114. A comparison of patient-controlled analgesia administered by the intravenous or intranasal route during the early postoperative period. (Abstract)

trial designed to compare the effectiveness of diamorphine administered as PCA utilising either the intranasal or intravenous routes. We investigated 52 consecutive patients undergoing primary lower limb joint replacement surgery. Patients were randomly allocated to receive PCA diamorphine, administered either intravenously (0.5 mg bolus, 3 min lockout) or intranasally (1.0 mg bolus, 3 min lockout). Pain was assessed using a Visual Analogue Score (VAS) at rest and on movement on five occasions over (...) A comparison of patient-controlled analgesia administered by the intravenous or intranasal route during the early postoperative period. Intranasal administration of lipophilic opioids has been shown to be an effective method of administration which is devoid of major side-effects. Whether it is as effective as intravenous administration for patient-controlled analgesia (PCA) has been investigated for fentanyl and pethidine, but not for diamorphine. This study reports a randomised controlled

2002 Anaesthesia Controlled trial quality: uncertain

3115. The development of the segmental pattern of skin sensory innervation in embryonic chick hind limb Full Text available with Trip Pro

The development of the segmental pattern of skin sensory innervation in embryonic chick hind limb 1. The development of dermatomes in the chick hind limb was investigated with both electrophysiological recording from and horseradish peroxidase (HRP) labelling of neurones in lumbosacral dorsal root ganglia (d.r.g.s). The embryonic stages studied spanned the period before and after cell death.2. In mature embryos, after the bulk of cell death, physiological mapping showed that the location (...) on the limb during the stages studied.6. Together these findings show that dermatomes on the chick hind limb do not develop by skin sensory axons simply growing to the nearest available skin, nor are axons towed to their final location by skin movements. Moreover, dermatomes are not shaped by cell death and the elimination of random or excessive axonal projections in the limb or the skin. It appears that skin sensory axons from each d.r.g. grow directly to their target skin along a defined set of pathways

1982 The Journal of physiology

3116. Activation patterns of embryonic chick hind limb muscles recorded in ovo and in an isolated spinal cord preparation. Full Text available with Trip Pro

Activation patterns of embryonic chick hind limb muscles recorded in ovo and in an isolated spinal cord preparation. Muscle activation patterns of embryonic chick hind limb muscles were determined from electromyographic (e.m.g.) recordings in an isolated spinal cord/hind limb preparation of stage 34-36 embryos, and were compared with in ovo e.m.g. activity from similarly staged embryos. Muscle activity in ovo consisted of periodically recurring sequences of bursts during which antagonistic (...) muscles often alternated and synergistic muscles were co-active, as compatible with their mature function. However, more variable behaviour was also observed. Burst sequences in ovo were often initiated by a short-duration, high-amplitude discharge that occurred synchronously in all muscles studied, and which was followed by a period of electrical silence that was longest in the flexor muscles. This type of activity has not been described previously in mature animals. In ovo movement sequences were

1984 The Journal of physiology

3117. Intensive, time-series measurement of upper limb recovery in the subacute phase following stroke. (Abstract)

Intensive, time-series measurement of upper limb recovery in the subacute phase following stroke. To discover if intensive monitoring of wrist extension would produce consistent recovery curves during the subacute period, and whether any impact of additional physiotherapy could be detected. We also investigated improved approaches to statistical analysis in single-case experiments.A randomized multiple-baseline experiment with very frequent assessment.Stroke rehabilitation unit.Four patients (...) with some active wrist movement less than seven weeks after stroke.Wrist extension was measured twice daily with an electrogoniometer for 3-4 weeks. Additional upper limb physiotherapy 115 minutes, twice per day) commenced after a randomly determined period.Speed and range of wrist movement.A logarithmic function was fitted to the data to produce recovery curves. In all cases, active range and maximum velocity of wrist extension rose gradually over time. Mean variability in range was <5

2003 Clinical rehabilitation Controlled trial quality: uncertain

3118. Functional outcome of botulinum toxin A injections to the lower limbs in cerebral palsy. (Abstract)

. At the end of this period, group 2 received BTX-A and physiotherapy and group 1 continued with physiotherapy alone. Assessment measures were the Gross Motor Function Measure (GMFM), the Vulpe Assessment Battery (VAB), joint range of movement, the Modified Ashworth Scale, and a parental questionnaire. Sustained gains in gross motor function were found in both groups of children but the only additional benefit found in group 1 was a significant increase in fine motor rating on the VAB. By contrast, parents (...) Functional outcome of botulinum toxin A injections to the lower limbs in cerebral palsy. We evaluated gross motor function following botulinum toxin A (BTX-A) injections in the lower limbs of children with spastic cerebral palsy in a randomized clinical trial, using a cross-over design. Forty-nine children (24 males, 25 females, age range 22 to 80 months) were randomly allocated to two groups: group 1 received BTX-A and physiotherapy, and group 2 received physiotherapy alone for 6 months

2002 Developmental Medicine and Child Neurology Controlled trial quality: uncertain

3119. A randomized, double-blind, placebo-controlled, dose-ranging study to compare the efficacy and safety of three doses of botulinum toxin type A (Dysport) with placebo in upper limb spasticity after stroke. (Abstract)

on functional disability was not statistically significant and was best at a dose of 1000 U. There were no statistically significant differences between the groups in the incidence of adverse events.The present study suggests that treatment with Dysport reduces muscle tone in patients with poststroke upper limb spasticity. Treatment was effective at doses of Dysport of 500, 1000, and 1500 U. The optimal dose for treatment of patients with residual voluntary movements in the upper limb appears to be 1000 U (...) A randomized, double-blind, placebo-controlled, dose-ranging study to compare the efficacy and safety of three doses of botulinum toxin type A (Dysport) with placebo in upper limb spasticity after stroke. We sought to define an effective and safe dose of botulinum toxin type A (Dysport) for the treatment of upper limb muscle spasticity due to stroke.This was a prospective, randomized, double-blind, placebo-controlled, dose-ranging study. Patients received either a placebo or 1 of 3 doses

2000 Stroke Controlled trial quality: predicted high

3120. Limb-kinetic apraxia in corticobasal degeneration: clinical and kinematic features. (Abstract)

and cortical inhibition. All five patients in the apraxic group exhibited a unilateral praxic deficit characterised by derangement of fractionated and segmental finger movements. QMC was significantly greater in apraxic than in nonapraxic patients (P < 0.02), revealing a chaotic movement with marked interfinger uncoordination. Conventional transcranial magnetic stimulation parameters were within normal limits in both groups of patients; however, the silent period was significantly shorter in the apraxic (...) limb when compared with control subjects (P < 0.001). Limb-kinetic apraxia is a distinctive disorder affecting the performance of finger and hand postures and movements over and above a corticospinal or basal ganglion deficit. Disruption of the frontoparietal circuit devoted to grasping and manipulation, together with defective cortical inhibition, which would also interfere with the selection and control of hand muscle activity, are the most likely underlying physiopathological mechanisms of limb

2003 Movement Disorders

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