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Peptic Ulcer Disease

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121. Peptic Ulcer Disease (Treatment)

Peptic Ulcer Disease (Treatment) Peptic Ulcer Disease Treatment & Management: Approach Considerations, Bleeding Peptic Ulcers, H pylori Infection Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache (...) =aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTgxNzUzLXRyZWF0bWVudA== processing > Peptic Ulcer Disease Treatment & Management Updated: Dec 21, 2018 Author: BS Anand, MD; Chief Editor: Philip O Katz, MD, FACP, FACG Share Email Print Feedback Close Sections Sections Peptic Ulcer Disease Treatment Approach Considerations The 2017 American College of Gastroenterology (ACG) guidelines for the treatment of H pylori infection (HPI) indicates that selection of an HPI management regimen should take into account any previous antibiotic exposure(s). The ACG also

2014 eMedicine.com

122. Peptic Ulcer Disease (Follow-up)

Peptic Ulcer Disease (Follow-up) Peptic Ulcer Disease Treatment & Management: Approach Considerations, Bleeding Peptic Ulcers, H pylori Infection Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache (...) =aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTgxNzUzLXRyZWF0bWVudA== processing > Peptic Ulcer Disease Treatment & Management Updated: Dec 21, 2018 Author: BS Anand, MD; Chief Editor: Philip O Katz, MD, FACP, FACG Share Email Print Feedback Close Sections Sections Peptic Ulcer Disease Treatment Approach Considerations The 2017 American College of Gastroenterology (ACG) guidelines for the treatment of H pylori infection (HPI) indicates that selection of an HPI management regimen should take into account any previous antibiotic exposure(s). The ACG also

2014 eMedicine.com

123. Peptic Ulcer Disease (Diagnosis)

Peptic Ulcer Disease (Diagnosis) Peptic Ulcer Disease: Background, Anatomy, Pathophysiology Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTgxNzUzLW92ZXJ2aWV3 processing > Peptic Ulcer Disease Updated: Dec 21 (...) , 2018 Author: BS Anand, MD; Chief Editor: Philip O Katz, MD, FACP, FACG Share Email Print Feedback Close Sections Sections Peptic Ulcer Disease Overview Background Gastric and duodenal ulcers usually cannot be differentiated based on history alone, although some findings may be suggestive (see ). Epigastric pain is the most common symptom of both gastric and duodenal ulcers. It is characterized by a gnawing or burning sensation and occurs after meals—classically, shortly after meals with gastric

2014 eMedicine Pediatrics

124. Peptic Ulcer Disease (Follow-up)

Peptic Ulcer Disease (Follow-up) Peptic Ulcer Disease Treatment & Management: Approach Considerations, Bleeding Peptic Ulcers, H pylori Infection Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache (...) =aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTgxNzUzLXRyZWF0bWVudA== processing > Peptic Ulcer Disease Treatment & Management Updated: Dec 21, 2018 Author: BS Anand, MD; Chief Editor: Philip O Katz, MD, FACP, FACG Share Email Print Feedback Close Sections Sections Peptic Ulcer Disease Treatment Approach Considerations The 2017 American College of Gastroenterology (ACG) guidelines for the treatment of H pylori infection (HPI) indicates that selection of an HPI management regimen should take into account any previous antibiotic exposure(s). The ACG also

2014 eMedicine Pediatrics

125. Peptic Ulcer Disease (Overview)

Peptic Ulcer Disease (Overview) Peptic Ulcer Disease: Background, Anatomy, Pathophysiology Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTgxNzUzLW92ZXJ2aWV3 processing > Peptic Ulcer Disease Updated: Dec 21 (...) , 2018 Author: BS Anand, MD; Chief Editor: Philip O Katz, MD, FACP, FACG Share Email Print Feedback Close Sections Sections Peptic Ulcer Disease Overview Background Gastric and duodenal ulcers usually cannot be differentiated based on history alone, although some findings may be suggestive (see ). Epigastric pain is the most common symptom of both gastric and duodenal ulcers. It is characterized by a gnawing or burning sensation and occurs after meals—classically, shortly after meals with gastric

2014 eMedicine Pediatrics

126. Peptic Ulcer Disease (Treatment)

Peptic Ulcer Disease (Treatment) Peptic Ulcer Disease Treatment & Management: Approach Considerations, Bleeding Peptic Ulcers, H pylori Infection Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache (...) =aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTgxNzUzLXRyZWF0bWVudA== processing > Peptic Ulcer Disease Treatment & Management Updated: Dec 21, 2018 Author: BS Anand, MD; Chief Editor: Philip O Katz, MD, FACP, FACG Share Email Print Feedback Close Sections Sections Peptic Ulcer Disease Treatment Approach Considerations The 2017 American College of Gastroenterology (ACG) guidelines for the treatment of H pylori infection (HPI) indicates that selection of an HPI management regimen should take into account any previous antibiotic exposure(s). The ACG also

2014 eMedicine Pediatrics

127. Gastritis and Peptic Ulcer Disease (Follow-up)

Gastritis and Peptic Ulcer Disease (Follow-up) Peptic Ulcer Disease Treatment & Management: Approach Considerations, Bleeding Peptic Ulcers, H pylori Infection Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache (...) =aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTgxNzUzLXRyZWF0bWVudA== processing > Peptic Ulcer Disease Treatment & Management Updated: Dec 21, 2018 Author: BS Anand, MD; Chief Editor: Philip O Katz, MD, FACP, FACG Share Email Print Feedback Close Sections Sections Peptic Ulcer Disease Treatment Approach Considerations The 2017 American College of Gastroenterology (ACG) guidelines for the treatment of H pylori infection (HPI) indicates that selection of an HPI management regimen should take into account any previous antibiotic exposure(s). The ACG also

2014 eMedicine Emergency Medicine

128. Peptic Ulcer Disease (Diagnosis)

Peptic Ulcer Disease (Diagnosis) Peptic Ulcer Disease: Background, Anatomy, Pathophysiology Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTgxNzUzLW92ZXJ2aWV3 processing > Peptic Ulcer Disease Updated: Dec 21 (...) , 2018 Author: BS Anand, MD; Chief Editor: Philip O Katz, MD, FACP, FACG Share Email Print Feedback Close Sections Sections Peptic Ulcer Disease Overview Background Gastric and duodenal ulcers usually cannot be differentiated based on history alone, although some findings may be suggestive (see ). Epigastric pain is the most common symptom of both gastric and duodenal ulcers. It is characterized by a gnawing or burning sensation and occurs after meals—classically, shortly after meals with gastric

2014 eMedicine.com

129. Gastritis and Peptic Ulcer Disease (Treatment)

Gastritis and Peptic Ulcer Disease (Treatment) Peptic Ulcer Disease Treatment & Management: Approach Considerations, Bleeding Peptic Ulcers, H pylori Infection Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache (...) =aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTgxNzUzLXRyZWF0bWVudA== processing > Peptic Ulcer Disease Treatment & Management Updated: Dec 21, 2018 Author: BS Anand, MD; Chief Editor: Philip O Katz, MD, FACP, FACG Share Email Print Feedback Close Sections Sections Peptic Ulcer Disease Treatment Approach Considerations The 2017 American College of Gastroenterology (ACG) guidelines for the treatment of H pylori infection (HPI) indicates that selection of an HPI management regimen should take into account any previous antibiotic exposure(s). The ACG also

2014 eMedicine Emergency Medicine

130. Gastritis and Peptic Ulcer Disease (Diagnosis)

Gastritis and Peptic Ulcer Disease (Diagnosis) Peptic Ulcer Disease: Background, Anatomy, Pathophysiology Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTgxNzUzLW92ZXJ2aWV3 processing > Peptic Ulcer Disease (...) Updated: Dec 21, 2018 Author: BS Anand, MD; Chief Editor: Philip O Katz, MD, FACP, FACG Share Email Print Feedback Close Sections Sections Peptic Ulcer Disease Overview Background Gastric and duodenal ulcers usually cannot be differentiated based on history alone, although some findings may be suggestive (see ). Epigastric pain is the most common symptom of both gastric and duodenal ulcers. It is characterized by a gnawing or burning sensation and occurs after meals—classically, shortly after meals

2014 eMedicine Emergency Medicine

131. Gastritis and Peptic Ulcer Disease (Overview)

Gastritis and Peptic Ulcer Disease (Overview) Peptic Ulcer Disease: Background, Anatomy, Pathophysiology Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTgxNzUzLW92ZXJ2aWV3 processing > Peptic Ulcer Disease (...) Updated: Dec 21, 2018 Author: BS Anand, MD; Chief Editor: Philip O Katz, MD, FACP, FACG Share Email Print Feedback Close Sections Sections Peptic Ulcer Disease Overview Background Gastric and duodenal ulcers usually cannot be differentiated based on history alone, although some findings may be suggestive (see ). Epigastric pain is the most common symptom of both gastric and duodenal ulcers. It is characterized by a gnawing or burning sensation and occurs after meals—classically, shortly after meals

2014 eMedicine Emergency Medicine

132. DLBS2411 Treatment for Ulcer Healing in Non-Bleeding Peptic Ulcers

gastric-epithelial mucous and bicarbonate secretion; anti-oxidative activity; and endothelial-nitric oxide (NO) formation. Recent study of DLBS2411 in healthy volunteers demonstrated the effective role and safety of DLBS2411 in suppressing intragastric acidity. Having such mechanisms of action, DLBS2411 is hypothesized to benefit in peptic ulcers. Condition or disease Intervention/treatment Phase Non-Bleeding Peptic Ulcers Drug: Omeprazole Drug: Placebo caplet of DLBS2411 Drug: DLBS2411 Drug: Placebo (...) Peptic Ulcer Pathologic Processes Duodenal Diseases Intestinal Diseases Gastrointestinal Diseases Digestive System Diseases Stomach Diseases Omeprazole Anti-Ulcer Agents Gastrointestinal Agents Proton Pump Inhibitors Enzyme Inhibitors Molecular Mechanisms of Pharmacological Action

2014 Clinical Trials

133. Single nucleotide polymorphism markers for low-dose aspirin-associated peptic ulcer and ulcer bleeding. (PubMed)

Single nucleotide polymorphism markers for low-dose aspirin-associated peptic ulcer and ulcer bleeding. In our previous study, the SLCO1B1 521TT genotype and the SLCO1B1*1b haplotype were significantly associated with the risk of peptic ulcer in patients taking low-dose aspirin (LDA). The aim of the present study was to investigate pharmacogenomic profile of LDA-induced peptic ulcer and ulcer bleeding.Patients taking 100 mg of enteric-coated aspirin for cardiovascular diseases and with a peptic (...) sequencing.Of 593 patients enrolled, 111 patients had a peptic ulcer and 45 had ulcer bleeding. The frequencies of the SLCO1B1*1b haplotype and CHST2 2082 T allele were significantly greater in patients with peptic ulcer and ulcer bleeding compared to the controls. After adjustment for significant factors, the SLCO1B1*1b haplotype was associated with peptic ulcer (OR 2.20, 95% CI 1.24-3.89) and CHST2 2082 T allele with ulcer bleeding (2.57, 1.07-6.17).The CHST2 2082 T allele as well as SLCO1B1*1b haplotype

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2014 Journal of gastroenterology and hepatology

134. Prevention of peptic ulcers with esomeprazole in patients at risk of ulcer development treated with low-dose acetylsalicylic acid: a randomised, controlled trial (OBERON). (PubMed)

trial.Cardiology, primary care and gastroenterology centres (n=240).Helicobacter pylori-negative patients taking daily low-dose ASA (75-325 mg), who fulfilled one or more of the following criteria: age ≥18 years with history of uncomplicated peptic ulcer; age ≥60 years with either stable coronary artery disease, upper gastrointestinal symptoms and five or more gastric/duodenal erosions, or low-dose ASA treatment initiated within 1 month of randomisation; or age ≥65 years. All patients were ulcer-free at study (...) Prevention of peptic ulcers with esomeprazole in patients at risk of ulcer development treated with low-dose acetylsalicylic acid: a randomised, controlled trial (OBERON). To determine whether once-daily esomeprazole 40 mg or 20 mg compared with placebo reduces the incidence of peptic ulcers over 26 weeks of treatment in patients taking low-dose acetylsalicylic acid (ASA) and who are at risk for ulcer development.Multinational, randomised, blinded, parallel-group, placebo-controlled

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2011 EvidenceUpdates

135. Impact of Cigarette Smoking on the Gastrointestinal Tract Inflammation: Opposing Effects in Crohn’s Disease and Ulcerative Colitis (PubMed)

Impact of Cigarette Smoking on the Gastrointestinal Tract Inflammation: Opposing Effects in Crohn’s Disease and Ulcerative Colitis Cigarette smoking is a major risk factor for gastrointestinal disorders, such as peptic ulcer, Crohn's disease (CD), and several cancers. The mechanisms proposed to explain the role of smoking in these disorders include mucosal damage, changes in gut irrigation, and impaired mucosal immune response. Paradoxically, cigarette smoking is a protective factor (...) for the development and progression of ulcerative colitis (UC). UC and CD represent the two most important conditions of inflammatory bowel diseases, and share several clinical features. The opposite effects of smoking on these two conditions have been a topic of great interest in the last 30 years, and has not yet been clarified. In this review, we summarize the most important and well-understood effects of smoking in the gastrointestinal tract; and particularly, in intestinal inflammation, discussing available

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2018 Frontiers in immunology

136. Challenges in the management of acute peptic ulcer bleeding. (PubMed)

Challenges in the management of acute peptic ulcer bleeding. Acute upper gastrointestinal bleeding is a common medical emergency worldwide, a major cause of which are bleeding peptic ulcers. Endoscopic treatment and acid suppression with proton-pump inhibitors are cornerstones in the management of the disease, and both treatments have been shown to reduce mortality. The role of emergency surgery continues to diminish. In specialised centres, radiological intervention is increasingly used (...) literature about the management of patients with bleeding peptic ulcers, identify directions for future clinical research, and suggest how mortality can be reduced.Copyright © 2013 Elsevier Ltd. All rights reserved.

2013 Lancet

137. Sleep Apnea and Risk of Peptic Ulcer Bleeding: A Nationwide Population-based Study (PubMed)

28,384 controls), 84 (0.24%) experienced peptic ulcer bleeding during a follow-up period of 3.57±2.61 years, including 32 (0.45% of patients with sleep apnea) from the sleep apnea cohort and 52 (0.18% of control) from the control group (log-rank test, P<.0001). In comparison with subjects without development of peptic ulcer bleeding, those with peptic ulcer bleeding were older and had a higher percentage of sleep apnea, coronary artery disease, peptic ulcer, ischemic stroke, and medication (...) Sleep Apnea and Risk of Peptic Ulcer Bleeding: A Nationwide Population-based Study Patients with sleep apnea sustain cessation of breath during sleep, leading to intermittent hypoxia, systemic inflammation, and sympathetic activation. These insults may contribute to initiation or progression of peptic ulcers. This retrospective matched-control cohort study explored the relationship of sleep apnea and subsequent development of peptic ulcer bleeding.From 2000 to 2009, patients with newly

2013 EvidenceUpdates

138. Machine learning model to predict recurrent ulcer bleeding in patients with history of idiopathic gastroduodenal ulcer bleeding. (PubMed)

Machine learning model to predict recurrent ulcer bleeding in patients with history of idiopathic gastroduodenal ulcer bleeding. Patients with a history of Helicobacter pylori-negative idiopathic bleeding ulcers have an increased risk of recurring ulcer complications.To build a machine learning model to identify patients at high risk for recurrent ulcer bleeding.Data from a retrospective cohort of 22 854 patients (training cohort) diagnosed with peptic ulcer disease in 2007-2016 were analysed (...) (age, baseline haemoglobin, and presence of gastric ulcer, gastrointestinal diseases, malignancies, and infections) identified patients with bleeding recurrence within 1 year with an area under the receiver operating characteristic curve (AUROC) of 0.648. When we set the IPU-ML cutoff value at 0.20, 27.5% of patients were classified as high risk for rebleeding with a sensitivity of 41.4%, specificity of 74.6%, and a negative predictive value of 91.1%. In the validation cohort, the IPU-ML identified

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2019 Alimentary Pharmacology & Therapeutics

139. Efficacy of vonoprazan compared to proton pump inhibitors for patients with peptic ulcers: a systematic review with meta-analysis

Efficacy of vonoprazan compared to proton pump inhibitors for patients with peptic ulcers: a systematic review with meta-analysis Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites. Email salutation (e.g. "Dr Smith" or "Joanne (...) studies per subgroup is required. ">Subgroup analyses A sensitivity analysis is conducted to assess the impact of decisions taken in the review process on the meta-analysis outcome. These decisions may have been made in various stages of the review, e.g. the decision to exclude certain disease models, the decision to pool certain units of measurement for an outcome, the choice of effect measure, how subgroup variables are stratified etc. In order to assess the robustness of the findings of the meta

2018 PROSPERO

140. Proton Pump Inhibitor Versus Histamine-2 Receptor Antagonist for the Prevention of Recurrent Peptic Ulcers

Recruitment Status : Recruiting First Posted : September 16, 2015 Last Update Posted : September 29, 2017 See Sponsor: Kaohsiung Veterans General Hospital. Information provided by (Responsible Party): Ping-I (William) Hsu, M.D., Kaohsiung Veterans General Hospital. Study Details Study Description Go to Brief Summary: Whether pantoprazole versus famotidine for the prevention of recurrent peptic ulcers in thienopyridine users remains unclear. Condition or disease Intervention/treatment Phase Peptic Ulcer (...) examination (within 2 months) reveals normal appearance or erythematous patches only (without subepithelial hemorrhages, erosions or ulcers). Peptic ulcers (a mucosal break ³ 5 mm in diameter) have been documented by a previous endoscopic examination. Subjects have received thienopyridine therapy for at least two weeks. Requiring long-term anti-platelet therapy for ischemic cardiovascular diseases. Exclusion Criteria: A history of gastric or duodenal surgery other than oversewing of a perforation

2015 Clinical Trials

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