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Peptic Ulcer Disease

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21. Second-look endoscopy for bleeding peptic ulcer disease: a decision-effectiveness and cost-effectiveness analysis

Second-look endoscopy for bleeding peptic ulcer disease: a decision-effectiveness and cost-effectiveness analysis Second-look endoscopy for bleeding peptic ulcer disease: a decision-effectiveness and cost-effectiveness analysis Second-look endoscopy for bleeding peptic ulcer disease: a decision-effectiveness and cost-effectiveness analysis Imperiale TF, Kong N Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract (...) was usually performed within 16 to 24 hours of the first endoscopy, and could be followed by surgery. Location/setting USA/secondary care. Methods Analytical approach: A decision tree was developed for the pathway of patients after a first endoscopy to treat bleeding in peptic ulcer disease. Patients who were assigned to no second endoscopy could have a second endoscopy if bleeding recurred. Second endoscopies could result in bleeding, complications, surgery, or death. The authors stated

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2012 NHS Economic Evaluation Database.

22. Banxia xiexin decoction for patients with peptic ulcer or chronic gastritis infected with helicobacter pylori: a systematic review of randomized controlled trials

Banxia xiexin decoction for patients with peptic ulcer or chronic gastritis infected with helicobacter pylori: a systematic review of randomized controlled trials Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability (...) species); sex (stratified per sex); duration of index ischemia (linear); stem cell dose (linear); blinding of outcome assessment reported (stratified yes vs no). For stratified analyses, a minimum number of 8 studies per subgroup is required. ">Subgroup analyses A sensitivity analysis is conducted to assess the impact of decisions taken in the review process on the meta-analysis outcome. These decisions may have been made in various stages of the review, e.g. the decision to exclude certain disease

2019 PROSPERO

23. The accuracy of Helicobacter pylori diagnostic tests in patients with peptic ulcer, a systematic review and meta-analysis

The accuracy of Helicobacter pylori diagnostic tests in patients with peptic ulcer, a systematic review and meta-analysis Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content of this registration record, any (...) cell dose (linear); blinding of outcome assessment reported (stratified yes vs no). For stratified analyses, a minimum number of 8 studies per subgroup is required. ">Subgroup analyses A sensitivity analysis is conducted to assess the impact of decisions taken in the review process on the meta-analysis outcome. These decisions may have been made in various stages of the review, e.g. the decision to exclude certain disease models, the decision to pool certain units of measurement for an outcome

2019 PROSPERO

24. Operative versus non-operative management of perforated peptic ulcers: a systematic review

Operative versus non-operative management of perforated peptic ulcers: a systematic review Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites (...) of outcome assessment reported (stratified yes vs no). For stratified analyses, a minimum number of 8 studies per subgroup is required. ">Subgroup analyses A sensitivity analysis is conducted to assess the impact of decisions taken in the review process on the meta-analysis outcome. These decisions may have been made in various stages of the review, e.g. the decision to exclude certain disease models, the decision to pool certain units of measurement for an outcome, the choice of effect measure, how

2019 PROSPERO

25. Acupoint catgut embedding for peptic ulcer: systematic review and meta-analysis

Acupoint catgut embedding for peptic ulcer: systematic review and meta-analysis Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content of this registration record, any associated files or external websites. Email (...) of outcome assessment reported (stratified yes vs no). For stratified analyses, a minimum number of 8 studies per subgroup is required. ">Subgroup analyses A sensitivity analysis is conducted to assess the impact of decisions taken in the review process on the meta-analysis outcome. These decisions may have been made in various stages of the review, e.g. the decision to exclude certain disease models, the decision to pool certain units of measurement for an outcome, the choice of effect measure, how

2019 PROSPERO

26. Time latencies of Helicobacter pylori eradication after peptic ulcer and risk of recurrent ulcer, ulcer adverse events, and gastric cancer: a population-based cohort study. (PubMed)

Time latencies of Helicobacter pylori eradication after peptic ulcer and risk of recurrent ulcer, ulcer adverse events, and gastric cancer: a population-based cohort study. Helicobacter pylori is associated with peptic ulcer disease and gastric cancer. Therefore we wanted to test how various lengths of delays in H pylori eradication therapy influence the risk of recurrent peptic ulcer, ulcer adverse events, and gastric cancer.This population-based nationwide Swedish cohort study included 29,032 (...) patients receiving H pylori eradication therapy after peptic ulcer disease in 2005 to 2013. Predefined time intervals between date of peptic ulcer diagnosis and date of eradication therapy were analyzed in relation to study outcomes. Cox regression provided hazard ratios (HRs) and 95% confidence intervals (95% CIs), adjusted for age, sex, comorbidity, history of ulcer disease, use of ulcerogenic drugs, and use of proton pump inhibitors (PPIs).Compared with eradication therapy within 7 days of peptic

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2017 Gastrointestinal endoscopy

27. The association between peptic ulcer diseases and mental health problems: A population-based study: a STROBE compliant article. (PubMed)

The association between peptic ulcer diseases and mental health problems: A population-based study: a STROBE compliant article. This study aimed to investigate the association between the prevalence of peptic ulcer disease (PUD) and mental health problems, such as severe stress, depressive mood, and suicidal ideation.The population-based cross-sectional study was comprised of 14,266 subjects participating in the fourth annual Korea National Health and Nutrition Examination survey from 2007

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2017 Medicine

28. Associations between cytokine gene polymorphisms and susceptibility to Helicobacter pylori infection and Helicobacter pylori related gastric cancer, peptic ulcer disease: A meta-analysis. (PubMed)

Associations between cytokine gene polymorphisms and susceptibility to Helicobacter pylori infection and Helicobacter pylori related gastric cancer, peptic ulcer disease: A meta-analysis. The aim of this study is to clarify the associations between IL-1B31C/T, IL-1B-511C/T, IL-8-251T/A gene polymorphisms and the risk of Helicobacter pylori (H. pylori) infection together with H. pylori-related gastric cancer (GC), peptic ulcer disease (PUD).All eligible literature published up to July 2016 were (...) polymorphisms might act as a risk factor to H. pylori-related diseases including GC or PUD.

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2017 PloS one

29. The Development of Diabetes after Subtotal Gastrectomy with Billroth II Anastomosis for Peptic Ulcer Disease. (PubMed)

The Development of Diabetes after Subtotal Gastrectomy with Billroth II Anastomosis for Peptic Ulcer Disease. A duodenal bypass after a Roux-en-Y gastric bypass operation for obesity can ameliorate the development of diabetes mellitus (DM). We attempted to determine the subsequent risk of developing DM after subtotal gastrectomy with Billroth II anastomosis (SGBIIA) for peptic ulcer disease (PUD).We identified 662 patients undergoing SGBIIA for PUD between 2000 and 2011 from the Longitudinal (...) Health Insurance Database as the study cohort, and we randomly selected 2647 controls from the peptic ulcer population not undergoing SGBIIA and were frequency-matched by age, sex, and index year for the control cohort. All patient cases in both cohorts were followed until the end of 2011 to measure the incidence of DM. We analyzed DM risk by using a Cox proportional hazards regression model.The patients who underwent SGBIIA demonstrated a lower cumulative incidence of DM compared with the control

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2016 PLoS ONE

30. Clinical Significance of Risk Factors for Asymptomatic Peptic Ulcer Disease (PubMed)

Clinical Significance of Risk Factors for Asymptomatic Peptic Ulcer Disease 29207859 2018 11 13 2234-2400 50 6 2017 Nov Clinical endoscopy Clin Endosc Clinical Significance of Risk Factors for Asymptomatic Peptic Ulcer Disease. 514-515 10.5946/ce.2017.159 Huh Cheal Wung CW Division of Gastroenterology, Department of Internal Medicine, Incheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Incheon, Korea. Kim Byung-Wook BW Division of Gastroenterology, Department

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2017 Clinical endoscopy

31. Function of Jiangzhong Hou Gu® Mi Xi™ in Patients With Spleen Qi Deficiency and Peptic Ulcer Diseases

Function of Jiangzhong Hou Gu® Mi Xiâ„¢ in Patients With Spleen Qi Deficiency and Peptic Ulcer Diseases Efficacy and Safety of Hou Gu Mi Xi in Patients With Peptic Ulcer Diseases - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more (...) studies before adding more. Efficacy and Safety of Hou Gu Mi Xi in Patients With Peptic Ulcer Diseases The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. of clinical studies and talk to your health care provider before participating. Read our for details. ClinicalTrials.gov Identifier: NCT03320538 Recruitment Status : Recruiting First Posted : October 25, 2017

2017 Clinical Trials

32. Statin Therapy Is Associated with Reduced Risk of Peptic Ulcer Disease in the Taiwanese Population (PubMed)

Statin Therapy Is Associated with Reduced Risk of Peptic Ulcer Disease in the Taiwanese Population Although statin use may affect the severity of chronic gastritis and gastric cancer, no data exists about the relationship between statin therapy and risk of peptic ulcer disease (PUD) in patients. We investigated the effect of statin use and the incidence of PUD from the Taiwan National Health Insurance Research Database (NHIRD). A total of 35,194 patients records for medical claims were enrolled

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2017 Frontiers in pharmacology

33. A Five-Year Review of Perforated Peptic Ulcer Disease in Irrua, Nigeria (PubMed)

A Five-Year Review of Perforated Peptic Ulcer Disease in Irrua, Nigeria Peptic ulcer perforation is a common cause of emergency admission and surgery. This is the first study that documents the presentation and outcome of management in Irrua, Nigeria.This is a prospective study of all patients operated on for perforated peptic ulcer between April 1, 2010, and March 31, 2015. A structured questionnaire containing patients' demographics, operation findings, and outcome was filled upon discharge (...) or death.There were 104 patients. 81 males and 23 females (M : F = 3.5 : 1). The age range was between 17 years and 95 years. The mean age was 48.99 years ± SD 16.1 years. The ratio of gastric to duodenal perforation was 1.88 : 1. Perforation was the first sign of peptic ulcer disease in 62 (59.6%). Pneumoperitoneum was detectable with plain radiographs in 95 (91%) patients. 72 (69.2%) had Graham's Omentopexy. Death rate was 17.3%.We note that gastric perforation is a far commoner disease in our environment

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2017 International scholarly research notices

34. Peptic ulcer disease and non-steroidal anti-inflammatory drugs (PubMed)

Peptic ulcer disease and non-steroidal anti-inflammatory drugs 28798512 2018 11 13 0312-8008 40 3 2017 Jun Australian prescriber Aust Prescr Peptic ulcer disease and non-steroidal anti-inflammatory drugs. 91-93 10.18773/austprescr.2017.037 Drini Musa M gastrotrACT, Canberra. eng Journal Article Review 2017 06 01 Australia Aust Prescr 7804938 0312-8008 misoprostol non-steroidal anti-inflammatory drugs (NSAIDs) peptic ulcers proton pump inhibitors Conflict of interest: none declared 2017 8 12 6 0

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2017 Australian Prescriber

35. Tim-3 Up-regulation in Patients with Gastric Cancer and Peptic Ulcer Disease (PubMed)

Tim-3 Up-regulation in Patients with Gastric Cancer and Peptic Ulcer Disease Background: T-cell immunoglobulin and mucin domain protein-3 (Tim-3), an inhibitory immunoregulatory receptor, has been recently implicated in tumor biology and tumor-associated immune suppression. In the present study, expression of Tim-3 was evaluated in gastric cancer (GC) and peptic ulcer disease (PUD) at both mRNA and protein levels. Methods: A total of 133 gastric tissue biopsies, comprising 43 from GC cases, 48 (...) in H. pylori positive and negative cases.Conclusion: Higher Tim-3 expression in patients with gastric cancer and peptic ulcer implies that it might be involved in immune regulation and establishment of these gastrointestinal diseases. Targeted immunotherapy by blocking of inhibitory receptors like Tim-3 could be a promising approach for gastric cancer treatment.Creative Commons Attribution License

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2017 Asian Pacific journal of cancer prevention : APJCP

36. The PU‐PROM: A patient‐reported outcome measure for peptic ulcer disease (PubMed)

The PU‐PROM: A patient‐reported outcome measure for peptic ulcer disease Patient-reported outcome measure (PROM) conceived to enable description of treatment-related effects, from the patient perspective, bring the potential to improve in clinical research, and to provide patients with accurate information. Therefore, the aim of this study was to develop a patient-centred peptic ulcer patient-reported outcome measure (PU-PROM) and evaluate its reliability, validity, differential item (...) functioning (DIF) and feasibility.To develop a conceptual framework and item pool for the PU-PROM, we performed a literature review and consulted other measures created in China and other countries. Beyond that, we interviewed 10 patients with peptic ulcers, and consulted six key experts to ensure that all germane parameters were included. In the first item selection phase, classical test theory and item response theory were used to select and adjust items to shape the preliminary measure completed by 130

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2017 Health expectations : an international journal of public participation in health care and health policy

37. Non-perforated peptic ulcer disease: multidetector CT findings, complications, and differential diagnosis (PubMed)

Non-perforated peptic ulcer disease: multidetector CT findings, complications, and differential diagnosis Despite availability of effective therapies, peptic ulcer disease (PUD) remains a major global disease, resulting from a combination of persistent Helicobacter pylori infection and widespread use of nonsteroidal anti-inflammatory drugs. Albeit endoscopy definitely represents the mainstay diagnostic technique, patients presenting to emergency departments with unexplained abdominal pain (...) an overview of current disease epidemiology and complications, it explains the appropriate CT acquisition and interpretation techniques, and reviews with several examples the cross-sectional findings of uncomplicated PUD. Afterwards, the CT features of PUD complications such as ulcer haemorrhage, gastric outlet obstruction, biliary and pancreatic fistulisation are presented.• Gastric and duodenal peptic ulcers are increasingly caused by nonsteroidal anti-inflammatory drugs • Multiplanar CT interpretation

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2017 Insights into imaging

38. Effect of Subjective and Objective Sleep Quality on Subsequent Peptic Ulcer Recurrence in Older Adults. (PubMed)

Effect of Subjective and Objective Sleep Quality on Subsequent Peptic Ulcer Recurrence in Older Adults. To examine the effect of subjective and objective sleep quality on subsequent recurrence of peptic ulcer disease (PUD) among older patients after Helicobacter pylori eradication.Eight grade A hospitals in China.Of 1689 older Chinese with H. pylori-infected PUD recruited between January 2011 and October 2014, H. pylori were eradicated and PUD was cleared in 1538 patients by the end of 2014

2019 Journal of the American Geriatrics Society

39. Distinctive aspects of peptic ulcer disease, Dieulafoy's lesion, and Mallory-Weiss syndrome in patients with advanced alcoholic liver disease or cirrhosis (PubMed)

Distinctive aspects of peptic ulcer disease, Dieulafoy's lesion, and Mallory-Weiss syndrome in patients with advanced alcoholic liver disease or cirrhosis To systematically review the data on distinctive aspects of peptic ulcer disease (PUD), Dieulafoy's lesion (DL), and Mallory-Weiss syndrome (MWS) in patients with advanced alcoholic liver disease (aALD), including alcoholic hepatitis or alcoholic cirrhosis.Computerized literature search performed via PubMed using the following medical subject (...) complication of aALD because of its frequency, severity, and associated mortality. Patients with cirrhosis have a markedly increased risk of PUD, which further increases with the progression of cirrhosis. Patients with cirrhosis or aALD and peptic ulcer bleeding (PUB) have worse clinical outcomes than other patients with PUB, including uncontrolled bleeding, rebleeding, and mortality. Alcohol consumption, nonsteroidal anti-inflammatory drug use, and portal hypertension may have a pathogenic role

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2016 World Journal of Gastroenterology

40. Comparison of 10-day sequential therapy with 7-day standard triple therapy for Helicobacter pylori eradication in inactive peptic ulcer disease and the efficiency of sequential therapy in inactive peptic ulcer disease and non-ulcer dyspepsia. (PubMed)

Comparison of 10-day sequential therapy with 7-day standard triple therapy for Helicobacter pylori eradication in inactive peptic ulcer disease and the efficiency of sequential therapy in inactive peptic ulcer disease and non-ulcer dyspepsia. Eradication rates of standard triple therapy for Helicobacter pylori infections have decreased in recent years due to a worldwide increase in bacterial resistance. Sequential therapy has the advantage of a two-phase treatment regimen and achieves (...) a superior result for H. pylori eradication in peptic ulcer disease. However, no study has yet compared the efficacy of sequential therapy for H. pylori eradication exclusively in inactive duodenal ulcer (iDU) or non-ulcer dyspepsia (NUD).We retrospectively recruited 408 patients with endoscopic proven iDU (170 patients) or NUD (238 patients) infected with H. pylori. Patients with iDU were assigned into two groups: iDU triple therapy group, 44 patients treated with 40 mg pantoprazole, 1000 mg amoxicillin

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2015 BMC Gastroenterology

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