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Pemphigoid Gestationis

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2. Pemphigoid gestationis and intravenous immunoglobulin therapy (PubMed)

Pemphigoid gestationis and intravenous immunoglobulin therapy Pemphigoid gestationis, which is also known as herpes gestationis, is a rare, pregnancy-associated, autoimmune bullous disease. Treatment depends on the severity of the disease for each patient and the safety and use of these drugs during pregnancy and breastfeeding must be taken into consideration to guide their use. We describe the therapeutic response of two cases of pemphigoid gestationis that did not respond to conventional (...) immunosuppressive therapy or adverse effects limited their use. Both patients eventually received treatment with intravenous immunoglobulin therapy, which resulted in clinical remission. This clinical improvement with disappearance of lesions and a reduction in pruritus was paralleled in a decline in Bullous Pemphigoid Disease Activity Index activity scores, which is a validated scoring system to measure the related condition, bullous pemphigoid.

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2018 International journal of women's dermatology

3. Pemphigoid gestationis: Clinical and histologic features of twenty-three patients (PubMed)

Pemphigoid gestationis: Clinical and histologic features of twenty-three patients 28560301 2018 11 13 2352-6475 3 2 2017 Jun International journal of women's dermatology Int J Womens Dermatol Pemphigoid gestationis: Clinical and histologic features of twenty-three patients. 86-90 10.1016/j.ijwd.2016.11.004 Hallaji Z Z Department of Dermatology, Razi Hospital, Tehran University of Medical Sciences, Tehran, Iran. Mortazavi H H Department of Dermatology, Razi Hospital, Tehran University of Medical

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2016 International journal of women's dermatology

4. A subset of patients with pemphigoid (herpes) gestationis has serological evidence of celiac disease. (PubMed)

A subset of patients with pemphigoid (herpes) gestationis has serological evidence of celiac disease. Pemphigoid (herpes) gestationis (PG) is an uncommon, self-limited disease with other autoimmune associations; however, celiac disease (CD) is not recognized as one.From 71 patients' sera submitted for herpes gestationis factor (HGF) testing over a 5-year period, 12 were consistent with PG demonstrating HGF and increased IgG BP180 antibody levels; these sera were tested for IgA and IgG

2018 International Journal of Dermatology

5. Pemphigoid gestationis: a case series and review of the literature. (PubMed)

Pemphigoid gestationis: a case series and review of the literature. Pemphigoid gestationis (PG) is a rare autoimmune disease associated with pregnancy. Clinically, it presents with severe pruritus that precedes the appearance of vesiculobullous lesions. It usually begins on the trunk and spread rapidly to other parts of the body. Mucosal lesions and facial involvement are rare. In this article, we are discussing three cases of PG. We will discuss clinical-pathological features and management.

2018 Journal of Dermatological Treatment

6. Pemphigoid gestationis (PubMed)

Pemphigoid gestationis Pemphigoid gestationis is a rare autoimmune skin disorder emerging exclusively during pregnancy. Topical and oral glucocorticoids as well as oral antihistamines are the standard medications administered during pregnancy, aiming to relieve pruritus and to suppress extensive blister formation. Obstetricians should be able to recognize and treat this rare clinical condition accordingly.

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2018 Clinical Case Reports

7. Severe pemphigoid gestationis associated with acute disseminated encephalomyelitis in the setting of a systemic disorder. (PubMed)

Severe pemphigoid gestationis associated with acute disseminated encephalomyelitis in the setting of a systemic disorder. Pemphigoid gestationis is a skin-specific autoimmune disorder that can sometimes present as the cutaneous manifestation of a multiorgan disease due to potentially common pathogenic mechanisms. We report a severe form of pemphigoid gestationis in a 32-year-old primigravida woman, who presented at 22 weeks of gestation with headaches and blurred vision, later developing

2017 Australasian Journal of Dermatology

8. Pemphigoid gestationis: current perspectives (PubMed)

Pemphigoid gestationis: current perspectives Many skin diseases can occur in pregnant women. However, a few pruritic dermatological conditions are unique to pregnancy, including pemphigoid gestationis (PG). As PG is associated with severe morbidity for pregnant women and carries fetal risks, it is important for the clinician to quickly recognize this disease and refer it for dermatological evaluation and treatment. Herein, we review the pathogenesis, clinical characteristics, and management

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2017 Clinical, cosmetic and investigational dermatology

9. Pemphigoid gestationis: a successful preventive treatment by rituximab. (PubMed)

Pemphigoid gestationis: a successful preventive treatment by rituximab. 27606493 2017 04 20 1468-3083 31 4 2017 Apr Journal of the European Academy of Dermatology and Venereology : JEADV J Eur Acad Dermatol Venereol Pemphigoid gestationis: a successful preventive treatment by rituximab. e206-e207 10.1111/jdv.13962 Tourte M M Department of Dermatology, Bichat Claude Bernard Hospital, Paris, France. Brunet-Possenti F F Department of Dermatology, Bichat Claude Bernard Hospital, Paris, France

2016 Journal of the European Academy of Dermatology and Venereology

10. New Technology Identifies Pemphigoid Gestationis by Detection of Anti-BP180 IgG, but Simultaneous Detection of Anti-BP230 IgG does not Improve Diagnosis. (PubMed)

New Technology Identifies Pemphigoid Gestationis by Detection of Anti-BP180 IgG, but Simultaneous Detection of Anti-BP230 IgG does not Improve Diagnosis. 27174635 2017 01 26 2017 05 05 1651-2057 97 1 2017 01 04 Acta dermato-venereologica Acta Derm. Venereol. Value of BIOCHIP Technology in the Serological Diagnosis of Pemphigoid Gestationis. 128-130 10.2340/00015555-2460 Sadik Christian D CD Department of Dermatology, Allergy, and Venereology, University of Lübeck, DE-23538 Lübeck, Germany (...) . christian.sadik@uksh.de. Pas Hendri H HH Bohlmann Michael K MK Mousavi Sadegh S Benoit Sandrine S Sárdy Miklós M Terra Jorrit B JB Lima Ana L AL Hammers Christoph M CM van Beek Nina N Bangert Christine C Zillikens Detlef D Schmidt Enno E eng Journal Article Sweden Acta Derm Venereol 0370310 0001-5555 IM Adult Diagnosis, Differential Female Humans Immunologic Techniques methods Pemphigoid Gestationis diagnosis immunology Pregnancy Sensitivity and Specificity 2016 5 14 6 0 2017 1 27 6 0 2016 5 14 6 0 ppublish

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2016 Acta Dermato-Venereologica

11. Pemphigoid Gestationis

Pemphigoid Gestationis Pemphigoid Gestationis Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Pemphigoid Gestationis Pemphigoid (...) Gestationis Aka: Pemphigoid Gestationis , Herpes Gestationis II. Pathophysiology Autoimmune skin disorder Associated with HLA-DR3, and HLA-DR4 III. Associated conditions or (rare) IV. Signs s and bullae form on , extremities V. Management Increased antepartum observation Oral s s s in severe cases VI. Complications Preterm delivery infant VII. Course Onset in second-half of pregnancy Improves in late pregnancy May be exacerbated in early postpartum period May recur in future pregnancies Images: Related

2018 FP Notebook

12. Pregnancy with Pemphigoid Gestationis: A Rare Entity (PubMed)

Pregnancy with Pemphigoid Gestationis: A Rare Entity Pemphigoid Gestationis (PG) is a rare autoimmune blistering disease with an incidence of 1/50000 pregnancies. Presentation in the second or third trimester is most common and tends to recur in subsequent pregnancies with earlier onset and a more severe course. Direct Immunofluorescence (DIF) staining is confirmatory on skin biopsy specimen. A 24-year-old female presented at 6 months period of gestation with increased blood pressure records

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2016 Journal of clinical and diagnostic research : JCDR

13. A severe and prolonged case of pemphigoid gestationis successfully treated with combination therapies. (PubMed)

A severe and prolonged case of pemphigoid gestationis successfully treated with combination therapies. 26521896 2017 03 06 2017 08 17 1365-2133 174 4 2016 Apr The British journal of dermatology Br. J. Dermatol. A severe and prolonged case of pemphigoid gestationis successfully treated with combination therapies. 925-7 10.1111/bjd.14265 Arakawa M M Department of Dermatology, Kurume University School of Medicine, and Kurume University Institute of Cutaneous Cell Biology, Fukuoka, Japan. Ohata C C (...) Diagnosis, Differential Drug Therapy, Combination Female Glucocorticoids administration & dosage Humans Pemphigoid Gestationis diagnosis therapy Pemphigoid, Bullous diagnosis Plasmapheresis methods Pregnancy Prenatal Diagnosis Treatment Outcome 2015 11 3 6 0 2015 11 3 6 0 2017 3 7 6 0 ppublish 26521896 10.1111/bjd.14265

2015 British Journal of Dermatology

14. Pemphigoid Gestationis Complicating an Egg Donation Pregnancy. (PubMed)

Pemphigoid Gestationis Complicating an Egg Donation Pregnancy. 26608214 2017 01 17 2017 04 18 1651-2057 96 5 2016 06 15 Acta dermato-venereologica Acta Derm. Venereol. Pemphigoid Gestationis Complicating an Egg Donation Pregnancy. 695-6 10.2340/00015555-2303 Guerra Liliana L Laboratory of Molecular and Cell Biology, Istituto Dermopatico dell'Immacolata (IDI)-IRCCS, 00167 Rome, Italy. l.guerra@idi.it. Mazzanti Cinzia C Calabresi Valentina V De Luca Naomi N Zambruno Giovanna G Di Zenzo Giovanni G (...) eng Case Reports Journal Article Sweden Acta Derm Venereol 0370310 0001-5555 0 Glucocorticoids VB0R961HZT Prednisone IM Adult Embryo Transfer Enzyme-Linked Immunosorbent Assay Female Fluorescent Antibody Technique, Indirect Glucocorticoids therapeutic use Humans Pemphigoid Gestationis diagnosis drug therapy Prednisone therapeutic use Pregnancy Pregnancy Complications diagnosis drug therapy Pregnancy Outcome 2015 11 27 6 0 2015 11 27 6 0 2017 1 18 6 0 ppublish 26608214 10.2340/00015555-2303

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2015 Acta Dermato-Venereologica

15. Pemphigoid Gestationis (Overview)

Pemphigoid Gestationis (Overview) Pemphigoid Gestationis: Background, Pathophysiology, Epidemiology Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTA2MzQ5OS1vdmVydmlldw== processing > Pemphigoid Gestationis (...) Updated: Jun 02, 2017 Author: Victor A Teran; Chief Editor: William D James, MD Share Email Print Feedback Close Sections Sections Pemphigoid Gestationis Overview Background Pemphigoid gestationis (PG) is a rare autoimmune bullous dermatosis of pregnancy (see the image below). The disease was originally named herpes gestationis for the herpetiform morphology of the blisters, but this term is a misnomer because pemphigoid gestationis is not related to or associated with any active or prior herpes virus

2014 eMedicine.com

16. Pemphigoid Gestationis (Treatment)

Pemphigoid Gestationis (Treatment) Pemphigoid Gestationis Treatment & Management: Medical Care, Consultations Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTA2MzQ5OS10cmVhdG1lbnQ= processing > Pemphigoid (...) Gestationis Treatment & Management Updated: Jun 02, 2017 Author: Victor A Teran; Chief Editor: William D James, MD Share Email Print Feedback Close Sections Sections Pemphigoid Gestationis Treatment Medical Care The goals of treatment are to relieve pruritus and to suppress extensive blister formation. To minimize the risk for the mother and fetus, use the lowest effective dose of medication to suppress disease activity. Even with optimum control, some blisters may continue to develop, and patients may

2014 eMedicine.com

17. Pemphigoid Gestationis (Follow-up)

Pemphigoid Gestationis (Follow-up) Pemphigoid Gestationis Treatment & Management: Medical Care, Consultations Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTA2MzQ5OS10cmVhdG1lbnQ= processing > Pemphigoid (...) Gestationis Treatment & Management Updated: Jun 02, 2017 Author: Victor A Teran; Chief Editor: William D James, MD Share Email Print Feedback Close Sections Sections Pemphigoid Gestationis Treatment Medical Care The goals of treatment are to relieve pruritus and to suppress extensive blister formation. To minimize the risk for the mother and fetus, use the lowest effective dose of medication to suppress disease activity. Even with optimum control, some blisters may continue to develop, and patients may

2014 eMedicine.com

18. Pemphigoid Gestationis (Diagnosis)

Pemphigoid Gestationis (Diagnosis) Pemphigoid Gestationis: Background, Pathophysiology, Epidemiology Edition: No Results No Results Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTA2MzQ5OS1vdmVydmlldw== processing > Pemphigoid Gestationis (...) Updated: Jun 02, 2017 Author: Victor A Teran; Chief Editor: William D James, MD Share Email Print Feedback Close Sections Sections Pemphigoid Gestationis Overview Background Pemphigoid gestationis (PG) is a rare autoimmune bullous dermatosis of pregnancy (see the image below). The disease was originally named herpes gestationis for the herpetiform morphology of the blisters, but this term is a misnomer because pemphigoid gestationis is not related to or associated with any active or prior herpes virus

2014 eMedicine.com

19. A resistant case of pemphigus gestationis successfully treated with cyclosporine (PubMed)

A resistant case of pemphigus gestationis successfully treated with cyclosporine Pemphigoid gestationis (PG) is a rare autoimmune blistering disease of pregnancy caused by antibasement membrane zone auto-antibodies. The usual clinical findings are multiple pruritic urticarial papules and plaques, target lesions, vesicles, and blisters that occur during the second and third trimesters of pregnancy or in the immediate postpartum period. The disease is often treated with topical corticosteroids

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2017 Interventional medicine & applied science

20. Suspicion of pulmonary embolism during treatment of pemphigoid gestationis (PubMed)

Suspicion of pulmonary embolism during treatment of pemphigoid gestationis Pemphigoid gestationis (PG), first described in 1872 by Laws Milton, is a rare autoimmune bullous disease of pregnancy and puerperium. Pemphigoid gestationis has been estimated to occur in 1: 50 000 pregnancies and usually presents in the second or third trimester with exacerbation after partum. This disease is caused by circulating IgG1 immunoglobulin against hemidesmosomal protein bullous pemphigoid BP180 (BPAG2) type (...) XVII collagen and less frequently BP230. We present a case of pemphigoid gestationis in primigravida with complications during treatment due to the suspicion of pulmonary embolism.

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2013 Advances in Dermatology and Allergology/Postȩpy Dermatologii i Alergologii

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