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Pelvic Relaxation

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61. Role of mechanical strain-activated PI3K/Akt signaling pathway in pelvic organ prolapse Full Text available with Trip Pro

OS signaling pathway in hUSLF. This process may be involved in the pathogenesis of POP as it results in relaxation and dysfunction of pelvic supports. (...) Role of mechanical strain-activated PI3K/Akt signaling pathway in pelvic organ prolapse Mechanical loading on pelvic supports contributes to pelvic organ prolapse (POP). However, the underlying mechanisms remain to be elucidated. Our previous study identified that mechanical strain induced oxidative stress (OS) and promoted apoptosis and senescence in pelvic support fibroblasts. The aim of the present study is to investigate the molecular signaling pathway linking mechanical force with POP

2016 Molecular medicine reports

62. Caspase-3 dependent nitrergic neuronal apoptosis following cavernous nerve injury is mediated via RhoA and ROCK activation in major pelvic ganglion Full Text available with Trip Pro

Caspase-3 dependent nitrergic neuronal apoptosis following cavernous nerve injury is mediated via RhoA and ROCK activation in major pelvic ganglion Axonal injury due to prostatectomy leads to Wallerian degeneration of the cavernous nerve (CN) and erectile dysfunction (ED). Return of potency is dependent on axonal regeneration and reinnervation of the penis. Following CN injury (CNI), RhoA and Rho-associated protein kinase (ROCK) increase in penile endothelial and smooth muscle cells. Previous (...) studies indicate that nerve regeneration is hampered by activation of RhoA/ROCK pathway. We evaluated the role of RhoA/ROCK pathway in CN regulation following CNI using a validated rat model. CNI upregulated gene and protein expression of RhoA/ROCK and caspase-3 mediated apoptosis in the major pelvic ganglion (MPG). ROCK inhibitor (ROCK-I) prevented upregulation of RhoA/ROCK pathway as well as activation of caspase-3 in the MPG. Following CNI, there was decrease in the dimer to monomer ratio

2016 Scientific reports

63. The Effects of Vaginal Tampon Training Added to Pelvic Floor Muscle Training in Stress Urinary Incontinence

of Medicine related topics: Arms and Interventions Go to Arm Intervention/treatment Active Comparator: control pelvic floor muscle training Behavioral: Pelvic Floor Muscle Training Pelvic floor muscle training consist of fast (2 second) and slow contractions (5-s contraction, 10-s hold, 5-s relaxation, totally 20-s). One set of exercises includes ten fast and ten slow voluntary PFM contractions (VPFMCs). During week 1 and 2, participants will be instructed to perform two sets of exercises per day (20 fast (...) The Effects of Vaginal Tampon Training Added to Pelvic Floor Muscle Training in Stress Urinary Incontinence The Effects of Vaginal Tampon Training Added to Pelvic Floor Muscle Training in Stress Urinary Incontinence - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies

2016 Clinical Trials

64. Trans-perineal Trigger Point Dry Needling for Chronic Pelvic Pain

by (Responsible Party): Shalini Wiseman, Cork University Hospital Study Details Study Description Go to Brief Summary: Chronic Pelvic Pain (CPP) are around 10% of gynaecology referrals.Non-relaxing pelvic floor dysfunction (NRPFD) is an under-appreciated cause for CPP with dyspareunia where no other pathology exists. The effectiveness of manual therapy in studies have shown statistically significant pre and post treatment differences.However no study has reviewed the efficacy of inclusion of trans- perineal (...) therapy Intervention to be administered is manual therapy with myofascial release of trigger points for pelvic floor muscles, pelvis and abdominal musculature. Procedure: Manual therapy Myofascial trigger point release technique is a technique used to help ease tight muscles. This technique involves palpating the tight muscle for the 'knot'/trigger point and gently applying pressure for 30-60 seconds to help ease out the trigger point. Other Name: myofascial release Active Comparator: Dry needling

2016 Clinical Trials

65. Differences in Pelvic Morphology Between Women With and Without Provoked Vestibulodynia. (Abstract)

Differences in Pelvic Morphology Between Women With and Without Provoked Vestibulodynia. Pelvic morphology has been suggested to reflect increased tone and reduced strength of the pelvic floor muscles (PFMs) in women with provoked vestibulodynia (PVD) compared to healthy controls. We aimed to determine whether there are differences in pelvic morphology in the resting state, on maximum voluntary contraction (MVC), or on maximum effort Valsalva maneuver (MVM) between women with and without (...) PVD.While imaged using ultrasound, 38 women with PVD and 39 controls relaxed their PFMs, performed 3 MVCs and performed 3 MVMs. Levator plate length (LPL), levator plate angle (LPA), and anorectal angle (ARA) were determined at rest, at MVC and at MVM. The displacement of the bladder neck (BN) on MVC and on MVM was also determined. Two-way ANCOVAs were used to evaluate the main effects of group and task, the interaction between group and task, and the effect of resting morphology on LPL, LPA, and ARA

2016 Journal Of Sexual Medicine

66. Randomized Trial of Tibial Nerve Stimulation Versus Pelvic Floor Exercises for Treatment of Overactive Bladder

width: 200 us; duration: 15min daily Other: "Tibial stimulation" and "pelvic floor exercises" A group will make tibial nerve stimulation and the other will make pelvic floor training. After 8 weeks the patients exchanges their therapeutic approaches for over 8 weeks Active Comparator: "Pelvic Floor Exercises" This group will make pelvic muscle training 3 times a day . In decubit dorsal posture, legs flexed and abductee. Perform pelvic floor contractions keeping 2 seconds and relaxing 4 seconds (...) for 10 times, and contractions keeping 4 seconds and relaxing 8 seconds for 10 times. Other: "Tibial stimulation" and "pelvic floor exercises" A group will make tibial nerve stimulation and the other will make pelvic floor training. After 8 weeks the patients exchanges their therapeutic approaches for over 8 weeks Outcome Measures Go to Primary Outcome Measures : Number of participants with Urinary incontinence [ Time Frame: 3 months ] Eligibility Criteria Go to Information from the National Library

2015 Clinical Trials

67. Efficacy of biofeedback plus transanal stimulation in the management of pelvic floor dyssynergia: a randomized trial. (Abstract)

Efficacy of biofeedback plus transanal stimulation in the management of pelvic floor dyssynergia: a randomized trial. The therapy of pelvic floor dyssynergia is mostly conservative and is based on a high-fiber diet, physical activity and biofeedback training. Our aim was to compare the outcome of biofeedback (manometric-assisted pelvic relaxation and simulated defecation training) plus transanal electrostimulation with standard therapy (diet, exercise, laxatives).Clinical, physiologic

2015 Techniques in coloproctology Controlled trial quality: uncertain

68. The Use of NMES With Pelvic Fracture Rehabilitation

The Use of NMES With Pelvic Fracture Rehabilitation The Use of NMES With Pelvic Fracture Rehabilitation - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. The Use of NMES With Pelvic Fracture Rehabilitation (...) to Brief Summary: The purpose of the study is to investigate if using an electrical stimulation machine to see if it can help strengthen the muscles around the hip during the first three months post pelvic fracture will help with the early stages of rehabilitation. Electrical stimulation is a treatment machine that uses an electrical current to cause a single muscle or a group of muscles to contract. This contraction helps strengthen injured muscles and helps with the healing process. It can also help

2015 Clinical Trials

69. Restoring Emotional, Sexual, and Physical Empowerment Through CBT & Trauma-sensitive Care: A Chronic Pelvic Pain Intervention

, dysfunctional sexual behavior, treatment avoidance. RESPECT's trauma-sensitive psychological intervention will 1) educate the patient about the relations between sexual abuse, PTS, and chronic pelvic pain 2) empower her by explaining that sexual abuse, chronic pelvic pain, and PTS are not her fault but she has the power to combat them 3) desensitize her to anxiety provoking components of the physical therapy intervention, and 4) teach her relaxation tools that she can use during physical therapy sessions (...) will attend 7, one-hour psychotherapy sessions, which will be concurrent with trauma-sensitive care at physical therapy appointments. Behavioral: Trauma-sensitive Care Psychological intervention education empowerment desensitization relaxation tools Physical therapy intervention techniques to address muscular tension empowerment comfort encouragement of trauma-related coping skills Outcome Measures Go to Primary Outcome Measures : Chronic pelvic pain [ Time Frame: 4 months ] Women will be asked to rate

2015 Clinical Trials

70. Efficacy of Acupuncture for Chronic Prostatitis/Chronic Pelvic Pain Syndromes

Efficacy of Acupuncture for Chronic Prostatitis/Chronic Pelvic Pain Syndromes Efficacy of Acupuncture for Chronic Prostatitis/Chronic Pelvic Pain Syndrome - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more (...) . Efficacy of Acupuncture for Chronic Prostatitis/Chronic Pelvic Pain Syndrome The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT02588274 Recruitment Status : Completed First Posted : October 27, 2015 Last Update Posted : February 15, 2019 Sponsor: Guang'anmen Hospital of China Academy of Chinese Medical

2015 Clinical Trials

71. Mindfulness Meditation for Chronic Pelvic Pain Management

meditation app, -- using comparison app with progressive muscle relaxation but no meditation no app Patients will complete health questionnaires, may be asked to comment in a focus group and record pain, medication changes, surgery and emergency medical visits Condition or disease Intervention/treatment Phase Chronic Pelvic Pain Behavioral: Mindfulness meditation Behavioral: Relaxation app Not Applicable Study Design Go to Layout table for study information Study Type : Interventional (Clinical Trial (...) Last Verified: June 2016 Individual Participant Data (IPD) Sharing Statement: Plan to Share IPD: Undecided Plan Description: This is a feasibility study. data will be used to inform design of a full-scale trial. Keywords provided by Queen Mary University of London: Mindfulness Headspace Psychological approaches Progressive muscle relaxation Additional relevant MeSH terms: Layout table for MeSH terms Pelvic Pain Pain Neurologic Manifestations Signs and Symptoms

2015 Clinical Trials

72. Effects of Antenatal Pelvic Floor Preparation Techniques for Childbirth

in the previous session. Other Name: Epi-No Vaginal Dilator Active Comparator: Pelvic floor muscles training Exercises emphasizing conscious muscle relaxation, i.e., considering a resting time based on the contraction time. The resting time was double of the sustaining time of each contraction up to the 38th week of pregnancy, after remaining fixed this relaxation time up to the moment of delivery. This time was chosen because during the expulsive labor phase, there is a need for the pelvic floor muscles (...) to consciously relax during a long period, in order to facilitate the descendants and rotational movements of the baby's head and consequently, its passage. This exercises does not aim only muscle strength but also contraction promotion, which aims body and perineal awareness, muscle tone, coordination and appropriate motor control to allow an active muscle relaxation in the second labor stage. Other: Pelvic floor muscles training Pregnant women allocated to this group will perform pelvic floor muscles

2015 Clinical Trials

73. Use of a Perineometer to Assess Pelvic Muscle Tone

Use of a Perineometer to Assess Pelvic Muscle Tone Use of a Perineometer to Assess Pelvic Muscle Tone - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Use of a Perineometer to Assess Pelvic Muscle Tone (...) 20, 2016 Sponsor: Duke University Information provided by (Responsible Party): Duke University Study Details Study Description Go to Brief Summary: The purpose of this study is to establish the range of pelvic floor pressure in groups of women, including women with and without pelvic pain, and compare the change in perineometer measurements between rest and maximum pelvic floor contraction in women with and without pelvic pain. Purpose is also to determine whether resting pelvic floor

2015 Clinical Trials

74. Evaluation of the efficacy of an exercise program for pregnant women with low back and pelvic pain: a prospective randomized controlled trial. (Abstract)

in the control group received usual care, comprised of routine clinical practice for pregnancy-related low back and pelvic pain.According to Mann-Whitney U test analysis results, there was a statistically significant difference between the control and intervention groups' Visual Analogue Scale during relaxation scores and Visual Analogue Scale during activity scores at the end of the study. According to Mann-Whitney U test analysis results, the change in the mean Oswestry Disability Index score (...) Evaluation of the efficacy of an exercise program for pregnant women with low back and pelvic pain: a prospective randomized controlled trial. To evaluate the effect of exercise programs on pregnant women with pregnancy-related low back and pelvic pain.Low back and pelvic pain during pregnancy is a major health problem due to its frequent occurrence and such pain can limit pregnant women in many of their daily activities.A randomized trial with a control group (n = 48) and an intervention group

2015 Journal of advanced nursing Controlled trial quality: uncertain

75. Overview of Pelvic Relaxation Syndromes

Overview of Pelvic Relaxation Syndromes Overview of Pelvic Relaxation Syndromes - Gynecology and Obstetrics - MSD Manual Professional Edition Brought to you by The trusted provider of medical information since 1899 SEARCH SEARCH MEDICAL TOPICS Common Health Topics Resources QUIZZES & CASES Quizzes Cases The trusted provider of medical information since 1899 SEARCH SEARCH MEDICAL TOPICS Common Health Topics Resources QUIZZES & CASES Quizzes Cases / / / / OTHER TOPICS IN THIS CHAPTER Test your (...) Model Vaginal Birth Video How to Deliver a Baby in Breech Presentation SOCIAL MEDIA Add to Any Platform Loading Topic Resources Female Pelvic Muscles (Sagittal) Pelvic relaxation syndromes result from laxities (similar to hernias) in the ligaments, fascia, and muscles supporting the pelvic organs (pelvic floor—see Figure: ). About 9% of women require surgical repair for a pelvic relaxation syndrome. Female Pelvic Muscles (Inferior) Common contributing factors include Childbirth (particularly vaginal

2013 Merck Manual (19th Edition)

76. A Study Examining the Use of Vaginal Nifedipine With Pelvic Floor Physical Therapy for Levator Myalgia and Pelvic Pain

instructing the patient to voluntarily relax the pelvic floor muscles, the resting tone will be measured using the Oxford scale, which is a validated digital assessment. Eligibility Criteria Go to Information from the National Library of Medicine Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts (...) A Study Examining the Use of Vaginal Nifedipine With Pelvic Floor Physical Therapy for Levator Myalgia and Pelvic Pain A Study Examining the Use of Vaginal Nifedipine With Pelvic Floor Physical Therapy for Levator Myalgia and Pelvic Pain - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum

2012 Clinical Trials

77. Controlling Urgency Through Relaxation Exercises

Controlling Urgency Through Relaxation Exercises Controlling Urgency Through Relaxation Exercises - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Controlling Urgency Through Relaxation Exercises (CURE (...) , University of California, San Francisco Study Details Study Description Go to Brief Summary: We propose to conduct a rigorous, 12-week, randomized controlled trial of two relaxation therapies in 160 ambulatory women who report an average of at least 3 urgency-associated voiding or incontinence episodes per day. Participants will be randomized in a 1:1 ratio to: 1) practice slowing their resting respiratory rate to 5 to 10 breaths per minute for at least 15 minutes/day at home using a portable guided

2014 Clinical Trials

78. Relaxed Vaginal Outlet (Diagnosis)

, 2016 Author: Megan Brady Shannon, MD; Chief Editor: Kris Strohbehn, MD Share Email Print Feedback Close Sections Sections Relaxed Vaginal Outlet Overview Background A woman may complain to her provider that her vaginal opening feels or appears enlarged. This can be the result of pelvic organ prolapse or a damaged perineal body. This problem is not life-threatening, but a woman may complain of a bulge coming out her vagina, sexual dysfunction, or defecatory dysfunction. The urogynecologic term (...) for this is an enlarged “genital hiatus”, although other providers may use the terms “relaxed vaginal outlet” or “enlarged vaginal introitus.” None of these terms are an actual diagnosis, but rather a physical exam finding of which a patient may or may not be symptomatic. Multiparous patient with an approximately 3cm vaginal introitus. Next: Problem There is no formal diagnosis for an enlarged vaginal introitus, as patients usually present with a specific complaint that is resultant from her pelvic organ support

2014 eMedicine.com

79. Relaxed Vaginal Outlet (Treatment)

Vaginal Outlet Treatment & Management Updated: Jun 30, 2016 Author: Megan Brady Shannon, MD; Chief Editor: Kris Strohbehn, MD Share Email Print Feedback Close Sections Sections Relaxed Vaginal Outlet Treatment Medical Therapy Conservative management for patients who complain about an enlarged vaginal introitus includes pelvic floor physical therapy (PFPT). This is a non-invasive treatment method in which specially trained physical therapists perform internal and external therapy aimed at strengthening (...) and relaxing the pelvic floor muscles. PFPT is a structured and comprehensive program that sometimes includes biofeedback therapy, which is visual confirmation the patient is contracting her muscles appropriately. An individualized home exercise program is also prescribed by the patient’s therapist. Coordinating the pelvic floor muscles along with behavioral modification education can lead to improvement and even resolution of many pelvic floor disorders. [ , ] Pessary use is another conservative treatment

2014 eMedicine.com

80. Relaxed Vaginal Outlet (Overview)

, 2016 Author: Megan Brady Shannon, MD; Chief Editor: Kris Strohbehn, MD Share Email Print Feedback Close Sections Sections Relaxed Vaginal Outlet Overview Background A woman may complain to her provider that her vaginal opening feels or appears enlarged. This can be the result of pelvic organ prolapse or a damaged perineal body. This problem is not life-threatening, but a woman may complain of a bulge coming out her vagina, sexual dysfunction, or defecatory dysfunction. The urogynecologic term (...) for this is an enlarged “genital hiatus”, although other providers may use the terms “relaxed vaginal outlet” or “enlarged vaginal introitus.” None of these terms are an actual diagnosis, but rather a physical exam finding of which a patient may or may not be symptomatic. Multiparous patient with an approximately 3cm vaginal introitus. Next: Problem There is no formal diagnosis for an enlarged vaginal introitus, as patients usually present with a specific complaint that is resultant from her pelvic organ support

2014 eMedicine.com

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