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81. Cobicistat (HIV infection) - Benefit assessment according to §35a Social Code Book V

Cobicistat (HIV infection) - Benefit assessment according to §35a Social Code Book V 1 Translation of Sections 2.1 to 2.5 of the dossier assessment Cobicistat (HIV-Infektion bei Jugendlichen) – Nutzenbewertung gemäß § 35a SGB V (Version 1.0; Status: 26 June 2020). Please note: This document was translated by an external translator and is provided as a service by IQWiG to English-language readers. However, solely the German original text is absolutely authoritative and legally binding. Extract (...) IQWiG Reports – Commission No. A20-37 Cobicistat (HIV infection in adolescents) – Benefit assessment according to §35a Social Code Book V 1 Extract of dossier assessment A20-37 Version 1.0 Cobicistat (HIV infection in adolescents) 26 June 2020 Institute for Quality and Efficiency in Health Care (IQWiG) - i - Publishing details Publisher Institute for Quality and Efficiency in Health Care Topic Cobicistat (HIV infection in adolescents) – Benefit assessment according to §35a Social Code Book V

2020 Plant signaling & behavior

82. Low-Risk Infant Ground Transport in the Care of a Registered Nurse: Practice Resource

NURSE STABLE INFANT NEEDING INTER-FACILITY TRANSPORT FOR OFF-SITE CONSULTATION CONTACT PTN AT 1-866-233-2337 SELECT OPTION 3: PRESCHEDULED MEDICAL APPOINTMENT BOOK GROUND AMBULANCE SENDING/HOME NICU RESPONSIBLE FOR: - RN - NEONATAL TRANSPORT EQUIPMENT INTER FACILITY TRANSPORT FOR PRESCHEDULED MEDICAL APPOINTMENT OF THE STABLE NEONATE FLOW DIAGRAM CALL BYPASS PTN GOES STRAIGHT TO BCAS PATIENT TRANSPORT COORDINATION CENTREPerinatal Services BC Low-Risk Infant Ground Transport in the Care (...) of a Registered Nurse 25 REFERENCES 1 Lee S, Zupancic J, Sale J, Pendray M, Whyte R, Brabyn D et al Cost-Effectiveness and Choice of Infant Transport Systems Medical Care 2002;40(8):705-716 2 Doronjski A Neonatal Land Transport Academic Journal of Pediatrics & Neonatology 2017;2(4) 3 Lupton B, Pendray M Regionalized neonatal emergency transport Seminars in Neonatology 2004;9(2):125-133 4 Mullaney D, Edwards W, DeGrazia M Family-Centered Care During Acute Neonatal Transport Advances in Neonatal Care 2014;14

2020 British Columbia Perinatal Health Program

83. Paediatric inflammatory multisystem syndrome temporally associated with COVID-19

Infect Dis Soc 2020; online ahead of print: DOI:10.1093/jpids/piaa062. Sharland M, Butler K, Cant A, et al, eds. Manual of Childhood Infections: The Blue Book (Oxford Specialist Handbooks in Paediatrics), 4th edn. London, U.K.: Oxford University Press, 2016. Kanegaye JT, Wilder MS, Molkara D, et al. Recognition of a Kawasaki disease shock syndrome. Pediatrics 2009;123(5):e783-9. Wang W, Gong F, Zhu W, Fu S, Zhang Q. Macrophage activation syndrome in Kawasaki disease: More common than we thought (...) ). Royal College of Paediatrics and Child Health (U.K.) Guidance on pediatric multisystem inflammatory syndrome temporally associated with COVID-19: www.rcpch.ac.uk/sites/default/files/2020-05/COVID-19-Paediatric-multisystem-%20inflammatory%20syndrome-20200501.pdf (Accessed June 17, 2020). Canadian Paediatric Surveillance Program. Study: COVID-19: www.cpsp.cps.ca/surveillance/study-etude/covid-19. Santé Publique France. COVID-19 : point épidémiologique du 14 mai 2020: https://www.santepubliquefrance.fr

2020 Canadian Paediatric Society

84. Interventions for anxiety in mainstream school-aged children with autism spectrum disorder (ASD) Full Text available with Trip Pro

, cognitive behavioral therapy; CCAL, Camp Cope‐A‐Lot; CPRS, Conners’ Parent Rating Scales; FIQ, full scale IQ; IT, intervention group; MASC, Multidimensional Anxiety Scale for Children; PARS, Pediatric Anxiety Rating Scale; RCADS, Revised Child Anxiety and Depression Scale; RCMAS, Revised Children's Manifest Anxiety Scale; SCARED, Screen for Child Anxiety Related Disorders; SCAS, Spence Child Anxiety Scale; STAI‐C, State‐Trait Anxiety Inventory for Children; SWQ, Social Worries Questionnaire; TAU (...) , Ziviani, & Rodger, ; Gjevik, Eldevik, Fjæran‐Granum, & Sponheim, ; Lecavalier, ). The prevalence of anxiety among school‐aged children is of particular concern considering that anxiety during this period has a negative impact on intellectual functioning and academic achievement, and broadly on a child's overall school‐functioning (Mazzone et al., ; Wood, ). School may present students with ASD particular cognitive, social and behavioral challenges that may increase levels of anxiety, and conversely

2020 Campbell Collaboration

85. Breastfeeding - Promoting and Supporting the Initiation, Exclusivity, and Continuation of Breastfeeding in Newborns, Infants and Young Children

is not accessible, with the goal of achieving the initiation and continuation of breastfeeding. Appendix H lists clinical indications for the temporary or permanent use of formula or other manufactured infant and young child feeding products.10 REGISTERED NURSES’ ASSOCIATION OF ONTARIO BACKGROUND Breastfeeding - Promoting and Supporting the Initiation, Exclusivity, and Continuation of Breastfeeding for Newborns, Infants, and Y oung Children Guiding Principles: This Guideline was created based on guiding (...) for infants and continued breastfeeding to two years or longer for young children to achieve healthy childhood development (3). More details on the WHO Global Nutrition Targets 2025 Breastfeeding Policy Brief, to increase the rate of exclusive breastfeeding in the first six months up to a minimum of 50 percent can be found at http://apps.who.int/iris/bitstream/10665/149022/1/WHO_NMH_NHD_14.7_eng.pdf?ua=1. The WHO’s Global Nutrition Targets 2025 Breastfeeding Goals are described in Figure 1

2018 Registered Nurses' Association of Ontario

86. The Role of Combination Therapy in Pediatric Inflammatory Bowel Disease: A Clinical Report from the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition

relevant to the pediatric population with IBD. This review sum- marizes and highlights key aspects of combination therapy for children and adolescents with IBD. COMBINATION THERAPY FOR THE MANAGEMENTOFPEDIATRICCROHNDISEASE Various studies, with differing levels of evidence, have evaluated the outcomes of combination therapy in adults and children with Crohn disease (CD). These data come from Received June 28, 2016; accepted November 17, 2017. From the Department of Paediatrics, University of Otago (...) , and the Division of Gastroenterology, Hepatology, and Nutrition, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH. Address correspondence and reprint requests to Professor Andrew S. Day, MD, FRACP, Department of Paediatrics, University of Otago, Christchurch, P.O. Box 4345, Christchurch 8140, New Zealand (e-mail: andrew.day@otago.ac.nz). The authors report no con?icts of interest. Copyright # 2017 by European Society for Pediatric Gastroenterology, Hepatology, and Nutrition and North American

2018 North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition

87. The SNMMI and EANM Procedural Guidelines for Diuresis Renography in Infants and Children

The SNMMI and EANM Procedural Guidelines for Diuresis Renography in Infants and Children PV2 SPECIAL CONTRIBUTION The SNMMI and EANM Procedural Guidelines for Diuresis Renography in Infants and Children Massoud Majd 1 ,ZviBar-Sever 2 ,Ana IsabelSantos 3 ,and DiegoDe Palma 4 1 SNMMI Pediatric Imaging Council, Children’s National Medical Center, Washington, DC; 2 EANM Paediatric Committee, Department of Nuclear Medicine, Schneider Children’s Medical Center, PetachTikva, Israel; 3 EANM Paediatric (...) bladder catheter allowed to drain freely into a closed col- lection bag.Anadditionaladvantageof continuous drainage of the radioactive urine from the bladder is signi?cant re- duction in gonadal radiation dose. However, catheterization, for the child, is an invasive and unpleasant procedure. There- fore, its routine use is controversial. But it is advised in infants and children with HUN, PUV, known VUR, or neu- ropathic bladder. In the absence of an indwelling bladder catheter, all toilet- trained

2018 Society of Nuclear Medicine and Molecular Imaging

88. Children's attachment: attachment in children and young people who are adopted from care, in care or at high risk of going into care

for attachment difficulties (see sections 1.4, 1.5 and 1.6). Interv Interventions for children and y entions for children and young people on the edge of care oung people on the edge of care Health and social care professionals should offer a video feedback programme to the parents of preschool-age children on the edge of care to help them: improve how they nurture their child, including when the child is distressed improve their understanding of what their child's behaviour means respond positively to cues (...) and expressions of the child's feelings behave in ways that are not frightening to the child improve mastery of their own feelings when nurturing the child. Interv Interventions for attachment difficulties in children and y entions for attachment difficulties in children and young people in the care system, subject to oung people in the care system, subject to special guardianship orders and adopted from care special guardianship orders and adopted from care Preschool-age children Health and social care

2015 National Institute for Health and Clinical Excellence - Clinical Guidelines

89. Randomized controlled trial of a book-sharing intervention in a deprived South African community: effects on carer-infant interactions and their relation to infant cognitive and socioemotional outcome. Full Text available with Trip Pro

in book sharing, a simple, inexpensive intervention that has been shown to benefit infant cognitive development in a low-middle income country, also shows promise for improving infant socioemotional outcomes in this context. Benefits are mediated by improvements in carer-infant interactions, particularly in book-sharing contexts.© 2016 Association for Child and Adolescent Mental Health. (...) Randomized controlled trial of a book-sharing intervention in a deprived South African community: effects on carer-infant interactions and their relation to infant cognitive and socioemotional outcome. Consistent with evidence from high-income countries (HICs), we previously showed that, in an informal peri-urban settlement in a low-middle income country, training parents in book sharing with their infants benefitted infant language and attention (Vally, Murray, Tomlinson, & Cooper, ). Here, we

2016 Journal of Child Psychology and Psychiatry Controlled trial quality: uncertain

90. [Propranolol - benefit assessment according to section 35a Social Code Book V (dossier assessment)]

assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation IQWiG. Propranolol – Nutzenbewertung gemass Section 35a SGB V. [Propranolol - benefit assessment according to section 35a Social Code Book V (dossier assessment)] Cologne: Institut fuer Qualitaet und Wirtschaftlichkeit im Gesundheitswesen (IQWiG). IQWiG-Berichte 260. 2014 Final publication URL Indexing Status Subject indexing assigned by CRD MeSH Childs; Hemangioma; Infant (...) [Propranolol - benefit assessment according to section 35a Social Code Book V (dossier assessment)] Propranolol – Nutzenbewertung gemass Section 35a SGB V [Propranolol - benefit assessment according to section 35a Social Code Book V (dossier assessment)] Propranolol – Nutzenbewertung gemass Section 35a SGB V [Propranolol - benefit assessment according to section 35a Social Code Book V (dossier assessment)] IQWiG Record Status This is a bibliographic record of a published health technology

2015 Health Technology Assessment (HTA) Database.

91. [Insulin degludec (new therapeutic indication) - Benefit assessment according to §35a Social Code Book V (dossier assessment)]

[Insulin degludec (new therapeutic indication) - Benefit assessment according to §35a Social Code Book V (dossier assessment)] Insulin degludec (neues anwendungsgebiet) – nutzenbewertung gemäß § 35a SGB V [Insulin degludec (new therapeutic indication) - Benefit assessment according to §35a Social Code Book V (dossier assessment)] Insulin degludec (neues anwendungsgebiet) – nutzenbewertung gemäß § 35a SGB V [Insulin degludec (new therapeutic indication) - Benefit assessment according to §35a (...) Social Code Book V (dossier assessment)] IQWiG Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation IQWiG. Insulin degludec (neues anwendungsgebiet) – nutzenbewertung gemäß § 35a SGB V. [Insulin degludec (new therapeutic indication) - Benefit assessment according to §35a Social Code Book V (dossier assessment)] Cologne: Institut fuer Qualitaet und

2015 Health Technology Assessment (HTA) Database.

92. Propranolol - Benefit assessment according to §35a Social Code Book V (dossier assessment)

d and examination of the IH d , evaluation of the target haemangioma for functional complications, ulceration and bleeding d a: These medications and therapeutic interventions were prohibited both at any time before enrolment of the child into the study and during the total study duration (96 weeks). b: These medications were also prohibited for the mothers 14 days before randomization and during the total study duration (96 weeks) if they were breastfeeding their children. c: These medications (...) Propranolol - Benefit assessment according to §35a Social Code Book V (dossier assessment) Extract 1 Translation of Sections 2.1 to 2.6 of the dossier assessment Propranolol – Nutzenbewertung gemäß § 35a SGB V (Version 1.0; Status: 26 November 2014). Please note: This translation is provided as a service by IQWiG to English-language readers. However, solely the German original text is absolutely authoritative and legally binding. IQWiG Reports – Commission No. A14-29 Propranolol – Benefit

2014 Institute for Quality and Efficiency in Healthcare (IQWiG)

93. Band ligation versus beta-blockers for primary prophylaxis of oesophageal variceal bleeding in children with chronic liver disease or portal vein thrombosis. Full Text available with Trip Pro

for primary prophylaxis of oesophageal variceal bleeding in children with chronic liver disease or portal vein thrombosis.We searched The Cochrane Hepato-Biliary Group Controlled Trials Register (February 2019), CENTRAL (December 2018), PubMed (December 2018), Embase Ovid (December 2018), LILACS (Bireme; January 2019), and Science Citation Index Expanded (Web of Science; December 2018). We scrutinised the reference lists of the retrieved publications and performed a manual search from the main paediatric (...) Band ligation versus beta-blockers for primary prophylaxis of oesophageal variceal bleeding in children with chronic liver disease or portal vein thrombosis. Portal hypertension commonly accompanies advanced liver disease and often gives rise to life-threatening complications, including haemorrhage from oesophageal and gastrointestinal varices. Variceal haemorrhage commonly occurs in children with chronic liver disease or portal vein obstruction. Prevention is therefore important. Following

2019 Cochrane

94. Fingolimod (multiple sclerosis in children and adolescents) - Addendum to Commission A18-87

Fingolimod (multiple sclerosis in children and adolescents) - Addendum to Commission A18-87 1 Translation of addendum A19-42 Fingolimod (multiple Sklerose bei Kindern und Jugendlichen) – Addendum zum Auftrag A18-87 (Version 1.0; Status: 28 May 2019). Please note: This translation is provided as a service by IQWiG to English-language readers. However, solely the German original text is absolutely authoritative and legally binding. Addendum 28 May 2019 1.0 Commission: A19-42 Version: Status (...) : IQWiG Reports – Commission No. A19-42 Fingolimod (multiple sclerosis in children and adolescents) – Addendum to Commission A18-87 1 Addendum A19-42 Version 1.0 Fingolimod – Addendum to Commission A18-87 28 May 2019 Institute for Quality and Efficiency in Health Care (IQWiG) - i - Publishing details Publisher: Institute for Quality and Efficiency in Health Care Topic: Fingolimod (multiple sclerosis in children and adolescents) – Addendum to Commission A18-87 Commissioning agency: Federal Joint

2019 Institute for Quality and Efficiency in Healthcare (IQWiG)

95. Guidelines for diagnosing and managing pediatric concussion

and managing recovery at home, school and play. The target population is every child/adolescent aged 5 to 18 years who has or may have sustained a concussion in the previous month. These guidelines do not apply to children under 5 years. Diagnosing concussion in children under five years is controversial because it relies heavily on the child’s ability to recognize and/or communicate his/her symptoms. Most preschoolers have not developed that capacity yet. As well, there are no validated tools for this age (...) care professionals. • Example: Emergency Department physicians, family physicians, pediatricians, nurse- practitioners, occupational and physical therapists, neuropsychologists. How: Provide verbal information. • Children/adolescents should not consume alcohol and/or recreational drugs at all— especially after a concussion. Chapter: Recommendations Guidelines for Diagnosing and Managing Pediatric Concussion 12 Tipsheet / List of Tools Why: • To prevent the child/adolescent from self-medicating

2019 CPG Infobase

96. Interventions for promoting participation in shared decision-making for children and adolescents with cystic fibrosis. Full Text available with Trip Pro

Interventions for promoting participation in shared decision-making for children and adolescents with cystic fibrosis. Shared decision-making is important in child and adolescent healthcare because there is growing international recognition of children and young people's rights to be included in decisions that affect them. In order for young people to participate effectively in shared decision-making they need to develop the skills of engagement with healthcare professionals and confidence (...) in interacting with them. They also need to learn how to manage their condition and treatments on their own when they move into adulthood. Children and young people who participate in shared decision-making in healthcare are likely to be more informed, feel more prepared, and experience less anxiety about the unknown. Significant improvements in cystic fibrosis (CF) survival over recent decades, due to improved therapies and better management of care, means that young people with CF are routinely

2019 Cochrane

97. The promotion of well?being among children exposed to intimate partner violence: A systematic review of interventions Full Text available with Trip Pro

., community‐based agency, outpatient mental health clinic). Kids’ Club is designed for children age 6–12 years and creates a safe space for children to identify and express emotions and build social, emotional and coping skills. MEP is a 10‐session parenting group that provides support to mothers of children age 6–12 years by empowering them to discuss the impact of the violence on their child's development and to build parenting competence. 3.3 How the intervention might work The potential pathway (...) evaluations. Finally, two meta‐analyses have synthesized the results of empirical evaluations of interventions designed to promote well‐being following exposure to IPV in childhood. However, these reviews differ from the current work in several important ways. First, Hackett et al. ( ) examined the overall impact of mental health‐focused interventions involving women and children in joint treatment. Results revealed effects in the medium to large range for child internalizing and externalizing

2019 Campbell Collaboration

98. Clinical Practice Guideline for the Assessment and Treatment of Children and Adolescents with Anxiety Disorders

Anxietydisordersareamongthemostcommonpsychiatricdisordersinchildrenandadolescents.Asreviewedinthisguideline,bothcognitive-behavioral therapy (CBT) and selective serotonin reuptake inhibitor (SSRI) medication have considerable empirical support as safe and effective short-term treatments for anxiety in children and adolescents. Serotonin norepinephrine reuptake inhibitor (SNRI) medication has some empirical support as an additional treatment option. In the context of a protracted severe shortage of child and adolescenttrained behavioral health specialists, research demonstrating convenient, ef?cient (...) , cost-effective, and user-friendly delivery mechanisms for safe and effective treatments for child and adolescent anxiety disorders is an urgent priority. The comparative effectiveness of anxiety treatments, delineation of mediators and moderators of effective anxiety treatments, long-term effects of SSRI and SNRI use in children and adolescents, and additional evaluation of the degree of suicide risk associated with SSRIs and SNRIs remain other key research needs. Key Words: clinical practice

2020 American Academy of Child and Adolescent Psychiatry

99. Immunizations - pneumococcal: Scenario: Children over 5 years of age, and adults diagnosed at increased risk

as discussed in Chapter 25 of Immunisation against infectious disease (the 'Green Book'), published by the Department of Health [ ]. What advice should i give? Explain the benefits of vaccination to the person, or their parent or carer, in particular that it helps prevent serious illness, including meningitis in young children. Information about vaccinations (including vaccine safety, risks and benefits, and individual vaccines) is available on the NHS website at . Reassure that vaccinations are safe (...) on advice to give about pneumococcal immunization are based on information in the chapter on vaccine safety and adverse effects following immunization in Immunisation against infectious disease (the 'Green Book') published by Public Health England (PHE) [ ] , and are pragmatic, based on what CKS considers to be good clinical practice. Explaining the benefits of vaccination Many parents find the process of having their children immunized distressing. Explaining the benefits of vaccination and giving

2020 NICE Clinical Knowledge Summaries

100. Immunizations - childhood: Scenario: Additional childhood immunizations

by the childhood immunization programme. This is a summary and is not comprehensive. For more information, consult (the 'Green Book') at www.gov.uk. Give additional vaccinations if the child: Has comorbidities which make them susceptible to certain preventable diseases (for example pneumococcal disease, influenza). See Table 1 for information on the additional vaccines required for people with underlying medical conditions. Is, or has been, exposed to an environment where infection with a preventable disease (...) Immunizations - childhood: Scenario: Additional childhood immunizations Scenario: Additional immunizations | Management | Immunizations - childhood | CKS | NICE Search CKS… Menu Scenario: Additional immunizations Immunizations - childhood: Scenario: Additional childhood immunizations Last revised in July 2020 Scenario: Additional childhood immunizations Which children require additional immunizations? Healthy children will not usually require additional vaccinations other than those provided

2020 NICE Clinical Knowledge Summaries

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