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Pediatric Auditory Screening

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161. Last Days of Life (PDQ®): Health Professional Version

, although benzodiazepines (such as lorazepam) or atypical antipsychotics typically exacerbate delirium, they may be useful in delirium related to alcohol withdrawal and for hyperactive delirium that is not controlled by antipsychotics and other supportive measures. In intractable cases of delirium, palliative sedation may be warranted. In dying patients, a poorly understood phenomenon that appears to be distinct from delirium is the experience of auditory and/or visual hallucinations that include loved

2016 PDQ - NCI's Comprehensive Cancer Database

162. Composite Resin and Amalgam Dental Filling Materials: A Review of Safety, Clinical Effectiveness and Cost-effectiveness

, renal pathologies, or immunoreactions RCT=randomized controlled trial ; SAE=severe adverse events; TEAE=treatment emergent adverse events; Composite Resin and Amalgam Dental Filling 17 Appendix 2: Title and abstract screening checklist Reviewer: Date: Ref ID: First Author (year): 1 What is the STUDY POPULATION in this article? Pediatric patients/ deciduous teeth to be restored (exclude) Pediatric patients/ mixed dentition to be restored (include) Pediatric patients/ permanent teeth to be restored (...) assessments, systematic reviews, meta-analyses, randomized controlled trials, and economic studies. Where possible, retrieval was limited to the human population. The electronic search was also limited to English language documents published between January 1, 2002 and April 30, 2012. The bibliographies of the retrieved health technology assessments, systematic reviews, and meta-analyses were searched manually for relevant clinical trials. Selection Criteria and Methods One reviewer screened citations

2012 Canadian Agency for Drugs and Technologies in Health - Rapid Review

163. Psychological, social and biological determinants of ill health (pSoBid)

and to the participants themselves. This study was funded by the Glasgow Centre for Population Health which is a partnership between NHS Greater Glasgow and Clyde, Glasgow City Council and the University of Glasgow, supported by the Scottish Government. Jennifer McLean July 2013 3Abbreviations and glossary AVLT Auditory Verbal Learning Test: assesses short-term auditory-verbal memory BMI Body mass index BP Blood pressure CHD Coronary heart disease cIMT Carotid intima-media thickness: a surrogate marker

2013 Glasgow Centre for Population Health

164. Temporomandibular disorders (TMDs)

and grinding during sleep or when awake [bruxism], nail biting, or excessive mouth opening during yawning). Consider using a such as that developed by the International Association for Dental Research — a score of 3 or more is a positive screening result indicative of a TMD. Any associated features, such as locking or clicking of the jaw, altered skin sensation, or any nasal or ear symptoms. The impact of symptoms on the person's quality of life, for example on sleep, mood, concentration, energy levels (...) opinion in review articles on TMDs [ ; ; ] and a review article on the differential diagnosis of facial pain [ ]. Assessment of clinical features The RDC/TMD Consortium Network provide a validated set of criteria to physically assess the temporomandibular joint (TMJ) and associated structures, and to screen for psychosocial co-morbidity [ ]. A six-item self-completed questionnaire has been developed in conjunction with the RDC/TMD to assess the nature of TMJ pain [ ], which is well validated and has

2016 NICE Clinical Knowledge Summaries

165. Consensus-Based Clinical Practice Guideline for the Management of Volatile Substance Use in Australia

history (e.g. illnesses and injuries, medical treatments, accommodation, occupation, relationships) • recreational substance use history (types of inhaled substances used, frequency, quantity, alcohol and other drug use) • brief cognitive assessment (e.g. Mini-Mental State Examination) • screening for mental health conditions using a validated instrument (e.g. Kessler Psychological distress Scale – K10, Strong Souls) • assessment of risk for violence or self-harm • physical examination • laboratory (...) investigations (full blood screen, urine drug screen), ECG if possible • pregnancy test for females, if indicated • further investigations as indicated. if any of these assessments cannot be made during the initial assessment, they should be completed as soon as possible (in stages, if necessary). CBR 6.2.2 70 3.8SuMMARY OF RECOMMENd ATiONS NATiONAL HEALTH ANd MEdiCAL RESEARCH COuNCiL Consensus-based clinical practice guideline for the management of volatile substance use in Australia 15 Recommendation T ype

2011 National Health and Medical Research Council

166. Cognitive Remediation Augmented With Transcranial Direct Current Stimulation (tDCS)

laptop (Wi-Fi or ethernet cable) Able to commit to the designated period of study training sessions with baseline and follow-up visits. Able to understand the informed consent process and provide consent to participate in the study Exclusion Criteria: Visual, auditory and motor deficits that would prevent full ability to understand study instructions or operate the tDCS device or study laptop, as judged by treating clinician or study staff Primary, uncontrolled psychiatric disorder that would (...) screening measures the substitutions as mentioned above will be used. Contacts and Locations Go to Information from the National Library of Medicine To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor. Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03049969 Contacts Layout table for location contacts Contact: Kathleen Sherman 646 501 7531 Contact: Kai Sherman 646 501 7531 Locations

2017 Clinical Trials

167. Is Cognitive Training Neuroprotective in Early Psychosis?

to determine whether a 12-week course of intensive cognitive training of auditory processing in young FEP patients delivered remotely as a stand-alone treatment is neuroprotective against neural tissue loss in auditory cortex (superior temporal gyrus, STG), and possibly in other cortical regions. The investigators will also observe the effects of training on white matter integrity in the brain. Condition or disease Intervention/treatment Phase Psychosis Healthy Device: Magnetic Resonance Imaging Behavioral (...) and gender matched controls who are psychologically and physically healthy will be recruited from the community to participate in this cohort. Outcome Measures Go to Primary Outcome Measures : Changes in Functional 7T MRI scans of the auditory cortex (superior temporal gyrus) [ Time Frame: 1 year ] The investigators will conduct 2 7T MRI scans over the course of one year to observe any changes in the functional, structural, and diffusion weight imaging between cohorts and over time. The investigators

2017 Clinical Trials

168. Test and Evaluation of Non-Invasive Neuro-Assessment Devices (NINAD: Neurokinetics, Inc, iPAS

: February 28, 2019 Groups and Cohorts Go to Group/Cohort Intervention/treatment NKI iPAS Diagnostic Protocol Research participants who qualify for this study will put on EKG leads, and then a non-invasive device called iPAS, which will record heart rate and eye tracking data while participants perform a task on the screen of the device. The testing session will not exceed 30 minutes. Participants will take a total of 3 recordings over a period of roughly 5 weeks. Device: NKI i-PAS Diagnostic Protocol (...) , saccade predictive horizontal, antisaccade (horizontal), self-paced saccade, saccade and reaction times, visual reaction time, auditory reaction time, gaze horizontal, light reflex, subjective visual (vertical) and subjective vertical horizontal. Several quantitative measures are computed from the data acquired in each test, and these measures are then employed in a multivariate diagnostic assessment. Outcome Measures Go to Primary Outcome Measures : Unit performance reliability [ Time Frame: Total

2017 Clinical Trials

169. Deep Brain Stimulation With LIFUP for Mild Cognitive Impairment and Mild Alzheimer's Disease

through medical record review Agreement to participate in a clinical and brain imaging study. Age 55 years or older. No significant cerebrovascular disease as determined by a modified Ischemic Score of ≤ 4. Availability of a study partner (next of kin, family member) to attend all visits and to provide surrogate consent should it be determined that the participant does not have capacity. Adequate visual and auditory acuity to allow neuropsychological testing. Screening laboratory tests and ECG without (...) . Initially, subjects will undergo a screening assessment with a study physician to determine medical and psychiatric history, establish AD diagnosis, and undergo a blood draw, if standard recent labs for dementia and EKG are unavailable. Subjects that meet criteria and agree to participate in the study will undergo a follow-up visit. In the baseline measurement visit, participants will first undergo neuropsychological testing. Participants will be randomly assigned to one of two LIFUP pulsing paradigms

2017 Clinical Trials

170. Interventions Targeting Sensory Challenges in Autism Spectrum Disorder: A Systematic Review. (Full text)

Interventions Targeting Sensory Challenges in Autism Spectrum Disorder: A Systematic Review. Sensory challenges are common among children with autism spectrum disorder (ASD).To evaluate the effectiveness and safety of interventions targeting sensory challenges in ASD.Databases, including Medline and PsycINFO.Two investigators independently screened studies against predetermined criteria.One investigator extracted data with review by a second. Investigators independently assessed risk of bias (...) nonverbal cognitive skills (low SOE). Studies of auditory integration-based approaches did not improve language (low SOE). Massage improved symptom severity and sensory challenges in studies with likely overlapping participants (low SOE). Music therapy studies evaluated different protocols and outcomes, precluding synthesis (insufficient SOE). Some positive effects were reported for other approaches, but findings were inconsistent (insufficient SOE).Studies were small and short-term, and few fully

2017 Pediatrics PubMed

171. Scoping review: Awareness of neurotoxicity from anesthesia in children in otolaryngology literature. (PubMed)

to January 2005 through December 2015. Articles were screened and reviewed based on predefined inclusion and exclusion criteria.Initial search generated 3,909 articles. After 72 full text articles were reviewed, only seven articles mentioned neurotoxicity as a risk of general anesthesia in pediatric patients.Despite the high volume of pediatric otolaryngologic procedures performed annually, there remains limited awareness in our literature discussing neurotoxicity as an outcome. Prospective data from (...) increased risk of adverse neurodevelopmental outcomes in children exposed to a single episode of general anesthesia prior to 3 to 4 years of age, with stronger evidence for multiple exposures in this age range. Otolaryngologists may subject children to general anesthesia via procedures or tests, including computed tomography, magnetic resonance imaging, and auditory brainstem response.PubMed, Embase, Scopus, and Web of Science Review.A scoping review using the above databases was performed limited

2017 Laryngoscope

172. Hearing Loss in Children With Asymptomatic Congenital Cytomegalovirus Infection. (Full text)

Hearing Loss in Children With Asymptomatic Congenital Cytomegalovirus Infection. To assess the prevalence, characteristics, and risk of sensorineural hearing loss (SNHL) in children with congenital cytomegalovirus infection identified through hospital-based newborn screening who were asymptomatic at birth compared with uninfected children.We included 92 case-patients and 51 controls assessed by using auditory brainstem response and behavioral audiometry. We used Kaplan-Meier survival analysis (...) of developing SNHL after age 5 years among case-patients was not different than in uninfected children. Overall, 2% of case-patients developed SNHL that was severe enough for them to be candidates for cochlear implantation.Copyright © 2017 by the American Academy of Pediatrics.

2017 Pediatrics PubMed

173. Treatment of Mild Cognitive Impairment With Transcutaneous Vagal Nerve Stimulation

electrical nerve stimulation device at 20Hz, 100 μs pulse width Device: Sham stimulation Sham stimulation will be performed using electrodes placed on earlobe Outcome Measures Go to Primary Outcome Measures : RBANS story learning and recall [ Time Frame: 5 minutes ] Story learning and recall, used to assess delayed memory Wechsler-IV Paired Associated [ Time Frame: 5 minutes ] Assessment tool that measures linguistic functions Phonemic and semantic fluency - Verbal Fluency Test- A 60 Second Screening (...) [ Time Frame: 5 minutes ] Assessment tools that measure executive and linguistic functions. Scores involve counting up the total number of animals or words that the individual is able to produce. A score of under 17 indicates concern Paced Auditory Serial Addition Test (PASAT) [ Time Frame: 10-15 minutes ] Measures sustained and divided attention and rate of information processing through serial addition task for adults. Sensitive to mild cognitive impairment. The score for the PASAT is the total

2017 Clinical Trials

174. Iowa Cochlear Implant Clinical Research Center Hybrid L24 and Standard Cochlear Implants in Profoundly Deaf Infants

to assess hearing aid benefit. It is also used post-cochlear implantation to chart the progress the child is making with his/her cochlear implant when other formalized speech perception tests are not appropriate. The Glendonald Auditory Screening Procedure Word Test (GASP) [ Time Frame: Post-operatively through study completion (child is 5 years of age) or until the child scores 90% or better in all test conditions ] Speech perception test that contains 12 single-syllable and multisyllable words (...) in pediatric subjects who have bilateral severe to profound hearing loss, meeting the criteria for cochlear implantation. Unlike a conventional cochlear implant, the Nucleus L24 is expected to preserve the regions of the cochlear partition that are apical to the electrode, thus leaving them available for possible future advances in the field of otolaryngology and hearing devices, such as mammalian hair cell regeneration techniques or improved implantable hearing devices. Whether or not this group

2017 Clinical Trials

175. Investigation on the Bidirectional Cortical Neuroprosthetic System

healthcare provider, study physicians, and any necessary consultants Willingness and ability to provide informed consent Screened by rehabilitation psychologist with a result showing that the participant has a stable psychosocial support system with caregiver capable of monitoring participant throughout the study Ability and willingness to travel to up to fifty miles to study location up to three days per week for the duration of the study Ability to understand and comply with study session instructions (...) eligibility to participate. In addition, the medical team has the right to withdraw the participant at any time if any of the exclusion criteria emerge and participants can withdraw at any time for any reason. Withdrawal details are outlined below exclusion criteria. Exclusion criteria include: Neurological conditions: Impaired receptive and/or expressive verbal communication skills Presence of memory impairment on the Rey Auditory Verbal Learning Test Intellectual impairment: score of 26 or less

2017 Clinical Trials

176. Noninvasive Brain Stimulation for Mild Cognitive Impairment

) Sexes Eligible for Study: All Accepts Healthy Volunteers: No Criteria Both Veterans and Non-Veterans may enroll if they meet the following criteria ** Inclusion Criteria: Diagnosed with amnestic Mild Cognitive Impairment (aMCI); Stable medications (including any dementia-related meds) for at least 4 weeks prior to Baseline; Geriatric Depression Scale score less than 6; Ability to obtain a motor threshold, determined during the screening process; Study partner available; living situation enables (...) attendance at clinic visits; Visual and auditory acuity adequate for neuropsychological testing; Good general health with no diseases expected to interfere with the study; Participant is not pregnant or of childbearing potential (i.e. women must be 2 years post-menopausal or surgically sterile); Modified Hachinski Ischemic score less than or equal to 4; Agree to DNA extraction for single nucleotide polymorphism (SNP) genotyping; Able to understand study procedures and comply with them for the entire

2017 Clinical Trials

177. MCI: CPAP Treatment of OSA (Memories2)

adjusted scores 28-35 (inclusive) on optional Telephone Interview for Cognitive Status Modified (pre-screen); Scoring 0-0.5 on the Clinical Dementia Rating Scale (CDR); Scoring 24-30 on the Mini Mental State Examination (MMSE) (exceptions may be made for participants with <8 years of education as determined by the clinical research team); Memory impairment approximately 1.0-1.5 standard deviations below normal (adjusted for age and education) determined by scores on the Logical Memory II a test from (...) will be able to answer questions about the study participant, and meets one of the following criteria: (a) lives with the participant; (b) spends at least 3 times per week in-person contact with the participant; (c) spends at least 3 times per week in phone contact with the participant; or (d) spends at least 10 hours per week in any combination of phone or in person contact; adequate visual and auditory acuity to allow testing; Post-menopause or surgically sterile; testability - willing and able

2017 Clinical Trials

178. Randomized Controlled Trial of Valganciclovir for Cytomegalovirus Infected Hearing Impaired Infants

to mandate this approach whereby infants under three weeks of age who fail their newborn hearing screening undergo CMV testing. In this trial, the hearing screen targeted approach will be used to identify patients eligible for participation in a double blind placebo controlled randomized clinical trial of antiviral valganciclovir therapy. The results of this trial will inform public policy, potentially shift our current clinical practice regarding pediatric hearing loss evaluation, and potentially offer (...) (symptomatic CMV) infants. These promising findings have given rise to a debate regarding the best method for identifying and treating the more numerous asymptomatic CMV-infected infants. One approach is to conduct universal newborn hearing screens, and then do CMV diagnostic testing only on the infants who fail the hearing screen. This targeted approach should identify those infants at greatest risk of developing progressive hearing loss and consequent communicative difficulties. Utah is the first state

2017 Clinical Trials

179. Evidence-Based Neurorehabilitation in Children With CP

and one more affected side, they often tend not to use the affected extremity resulting in the phenoema of developmental disregard. Recent evidence suggests that constraint-induced therapy (CIT) is the most effective technique to improve the use of the affected hand and reduce the developmental disregard in children with CP. However, despite the cumulative evidence supporting the effects of pediatric CIT, the concerns of feasibility and gaps of current knowledge prompt us to conduct this current (...) compartment to another within 60 seconds. In recent years, it has increasingly been used to assess gross manual dexterity of the affected versus the non-affected hand in children and young adolescents with hemiplegia cerebral palsy. "change" Pediatric Motor Activity Log-Revised (PMAL-R) [ Time Frame: Intensive and CIT Model Program: baseline, 1 week, 2 months, 6 months; Distributed CIT Model Program: baseline, 1 months, 2 months, 6 months ] The PMAL-R is adapted from the Pediatric Motor Activity Log (Taub

2017 Clinical Trials

180. Reducing Breast Cancer-related Fatigue and Improving Cognition With Non-Invasive Brain Stimulation

transmission beneath scalp electrodes. Other Names: Transcranial Direct Current Stimulation NeuroConn DC Stimulator Plus Model 0021 Outcome Measures Go to Primary Outcome Measures : Change on Paced Auditory Serial Attention Test [ Time Frame: 6 weeks ] Change in auditory working memory Secondary Outcome Measures : Change on Functional Assessment of Cancer Therapy Cognitive Scale [ Time Frame: 7 weeks ] Change in subjective cognitive functioning Change in Multidimensional Fatigue Symptom Inventory- SF (...) comprehension; and, sufficient literacy to complete study forms and questionnaires. Patient understands the study regimen, its requirements, risks, and discomforts, and is able and willing to sign an informed consent form. Exclusion Criteria: Evidence of recurrent breast cancer at the time of enrollment. Depression or anxiety as defined either by ongoing pharmacological treatment for depression or anxiety or a HADS score on initial screening. Dementia as assessed by a MMSE score on initial screening. Known

2017 Clinical Trials

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