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Pediatric Auditory Screening

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121. A Digital App to Aid Detection, Monitoring, and Management of Dyslexia in Young Children (DIMMAND): Protocol for a Digital Health and Education Solution Full Text available with Trip Pro

A Digital App to Aid Detection, Monitoring, and Management of Dyslexia in Young Children (DIMMAND): Protocol for a Digital Health and Education Solution Dyslexia, a specific learning difficulty and a disability as defined in the Equality Act 2010, is a lifelong condition that affects a child from the start of education. Dyslexia is characterized by difficulties in language processing (reading, spelling, and writing) which do not correspond with the child's general intellectual abilities (...) and professionals, and an overall understanding of the market. We comprehensively defined the ethical, privacy, and data security issues. The detailed design spec of the games, the methodology to be followed to interpret the results, and flow diagrams illustrating how the game screens will be presented was completed. As proof of concept, a few reading, visual, and auditory games were developed and successfully tested by stakeholders on different digital devices. The stakeholders provided regular feedback

2018 JMIR Research Protocols

122. Clinical Assessment and Brain Findings in a Cohort of Mothers, Fetuses and Infants Infected with Zika Virus. Full Text available with Trip Pro

of apparent diffusion coefficient values showed microstructural changes. Microcephaly was present in 33.3-58.3% of the cases at referral and was present at delivery in 55.6-77.8% of cases. At birth, most of the affected neonates (55.6-77.8%) had head circumference measurements >3 standard deviations below the mean. Postnatal imaging studies confirmed brain malformations that were detected prenatally. Auditory screening results were normal in 2 cases that were assessed. Visual screening showed different (...) Clinical Assessment and Brain Findings in a Cohort of Mothers, Fetuses and Infants Infected with Zika Virus. Congenital Zika virus (ZIKV) infection can be detected in both the presence and absence of microcephaly and manifests as a number of signs and symptoms that are detected clinically and by neuroimaging. However, to date, qualitative and quantitative measures for the purpose of diagnosis and prognosis are limited.Main objectives of this study conducted on fetuses and infants with confirmed

2018 American Journal of Obstetrics and Gynecology

123. Extremely common radiographic finding of cochlear nerve deficiency among infants with prelingual single-sided deafness and its clinical implications. (Abstract)

undergoing newborn hearing screening program were retrospectively reviewed. Twenty-four consecutive well infants without risk factors who had a confirmed diagnosis of prelingual SSD under the age of 1 year and who underwent internal auditory canal (IAC) magnetic resonance imaging (MRI) were included. The sizes of cochlear nerve (CN), IAC, and cochlear nerve canal (CNC) were measured on MRI. The presence of CND was visually determined by comparing the CN size to the ipsilateral facial nerve (FN (...) Extremely common radiographic finding of cochlear nerve deficiency among infants with prelingual single-sided deafness and its clinical implications. To clarify the common radiographic findings of audiologically documented prelingual single-sided deafness (SSD) and identify the prevalence of cochlear nerve deficiency (CND) in SSD infants referred from the newborn hearing screening program.Between March 2012 and March 2017, the records of all infants referred to our otology clinic after

2018 International Journal of Pediatric Otorhinolaryngology

124. Role of Targeted Next Generation Sequencing in the Etiological Work-Up of Congenitally Deaf Children. (Abstract)

 = 1), and auditory neuropathy (n = 1).A definite genetic cause was found in 25 (50%) of congenital, bilaterally deaf children. Our data show that implementation of a gene panel improves the diagnostic yield for etiological work-up of congenital profound HL to 86%. Identification of the etiology of congenital HL may contribute to predicting outcomes of cochlear implantation. (...) Role of Targeted Next Generation Sequencing in the Etiological Work-Up of Congenitally Deaf Children. The purpose of this study is to report the results of a comprehensive etiological work-up for congenitally deaf children including targeted next generation sequencing.Retrospective case review.Tertiary referral center.Fifty children with congenital, bilateral profound hearing loss (HL) (>90 dBnHL).Etiological work-up included testing for pathogenic variants in GJB2, a phenotype driven genetic

2018 Otology and Neurotology

125. An audiological evaluation of syndromic and non-syndromic craniosynostosis in pre-school going children. (Abstract)

An audiological evaluation of syndromic and non-syndromic craniosynostosis in pre-school going children. To study the audiological outcome and early screening of pre-school going children with craniosynostosis under follow-up at the University of Malaya Medical Center(UMMC), Kuala Lumpur, Malaysia over a 10 year period.A retrospective descriptive cohort study on the audiological findings detected during the first hearing assessment done on a child with craniosynostosis using otoacoustic (...) hearing loss is more likely to be present in a child with syndromic craniosynostosis (p < 0.05).Our study suggested that children who are born with syndromic craniosynostosis were more likely to suffer from a hearing loss, including that of a severe to profound degree compared to children with non-syndromic craniosynostosis. In addition to that, hearing loss is more likely to be detected when the first hearing test is done at a later age, and this can be an irreversible sensorineural hearing loss. We

2018 International Journal of Pediatric Otorhinolaryngology

126. Longitudinal Development of Distortion Product Otoacoustic Emissions in Infants With Normal Hearing. Full Text available with Trip Pro

Longitudinal Development of Distortion Product Otoacoustic Emissions in Infants With Normal Hearing. The purpose of this study was to describe normal characteristics of distortion product otoacoustic emission (DPOAE) signal and noise level in a group of newborns and infants with normal hearing followed longitudinally from birth to 15 months of age.This is a prospective, longitudinal study of 231 infants who passed newborn hearing screening and were verified to have normal hearing. Infants were (...) frequencies. DPOAE noise level increased only slightly with age over the first year with the highest noise levels in the 12-month-old age range. Minor, nonsystematic effects for NICU history, race, and gestational age at birth were found, thus these results were generalizable to commonly seen clinical populations.DPOAE levels were related to wideband middle ear absorbance changes in this large sample of infants confirmed to have normal hearing at auditory brainstem response and visual reinforcement

2018 Ear and hearing

127. Safety and Tolerability Study of VTS-270 in Pediatric Participants With Niemann-Pick Type C (NPC) Disease

and running) that only measures skills to 36 months. The raw score is reported for each subscale domain. The potential score ranges are as follows: Visual Reception: 33 items, score range=0-50, Fine Motor: 30 items, score range= 0-49, Receptive Language: 33 items, score range= 0-48, Expressive Language: 28 items, score range= 0-50. A higher raw score indicates more advanced abilities in that section. Change From Baseline in Auditory Brainstem Response (ABR) Assessed Using Standard Clinical Pediatric Score (...) (hearing threshold). Other parameters of interest include amplitude (the number of neurons firing), latency (the speed of transmission), interpeak latency (the time between peaks), and interaural latency (the difference in wave V latency between ears). The interpeak latency I-V interval (or central transmission time) is considered the most reliable index of brainstem function. Auditory brainstem response assessments were based on standard clinical pediatric score criteria: mild hearing loss: 21-40

2018 Clinical Trials

128. Metformin for Motor and Cognitive Improvement in Children With Cerebral Palsy: A Feasibility Study

: Not yet recruiting First Posted : October 18, 2018 Last Update Posted : January 16, 2019 See Sponsor: Holland Bloorview Kids Rehabilitation Hospital Collaborator: The Hospital for Sick Children Information provided by (Responsible Party): Holland Bloorview Kids Rehabilitation Hospital Study Details Study Description Go to Brief Summary: This study will focus on the feasibility of Metformin use in children with cerebral palsy (CP) on improving gross motor function. The study design is a phase II (...) weeks intervention period. This study will be done at two different locations in Toronto 1) Holland Bloorview Kids Rehabilitation Hospital and 2) the Hospital for Sick Children (SickKids). Each participant will be asked to go to both hospitals to do different tests and assessments for the study. Fifty participants with bilateral spastic CP age 5 to 12 with evidence of white matter imaging (WMI) and gross motor function classification system (GMFCS) levels II-V will be recruited for participation

2018 Clinical Trials

129. The Effect of Spontaneous Hand Gestures on Stuttering in Children With Down Syndrome

NJ, Geraerdts, JPM, Prok JC, editors. Leerboek medische genetica [Textbook medical genetics]. Maarssen: Elsevier gezondheidszorg; c2005. 430 p. (Cassiman JJ, Engelen JJM, editors. Chromosomale overerving [Chromosomal inheritance]; vol.6).Dutch Chapman RS (1997). Language development in children and adolescents with Down syndrome. Ment Retard Develop Dis Res Rev. 1997; 3: 307-312. Fletcher P, Macwhinney B, editors. The handbook of child language. Oxford,UK:Blackwell; c1995. 800 p. (Chapman RS (...) The Effect of Spontaneous Hand Gestures on Stuttering in Children With Down Syndrome The Effect of Spontaneous Hand Gestures on Stuttering in Children With Down Syndrome - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before

2018 Clinical Trials

130. Aripiprazole Oral Solution in the Treatment of Children and Adolescents With Autistic Disorder

. In addition, the Childhood Autism Rating Scale (CARS) score is ≥30. The subject has a Clinical Global Impressions-Severity (CGI-S) score ≥ 4 AND an ABC-I subscale score ≥18 at screening (Visit 1 or Visit 1a) and baseline (V2). Environmental factors can be consistent throughout the trial period. The subject is a male or female child or adolescent 6 to 17 years of age (6 ≤ age ≤ 17) at Baseline (V2). Exclusion Criteria: Women of childbearing potential (WOCBP) who are unwilling or unable to use an acceptable (...) Phase will serve multiple purposes: to allow for appropriate washout of prohibited medications; to allow for review of screening data; to establish a pre-treatment baseline of key outcome measures. Treatment Phase: The duration of the treatment is 8 weeks. The purpose of the treatment phase is to evaluate the efficacy, safety, tolerability and steady-state plasma trough concentration of aripiprazole in the treatment of serious behavioral problems in children and adolescents with a diagnosis

2018 Clinical Trials

131. Occupational Therapy With Ayres Sensory Integration Approach for School-age Children

for assessing the sensory integration and praxis of children between the ages of four years and eight years, eleven months. This study used six subtests of the SIPT - standing and walking balance, postural praxis, post-rotary nystagmus, motor accuracy, sequencing praxis, and graphesthesia - based on expert opinions. SIPT offers is computer scoring and interpretation. Therapists simply record the child's performance and enter into the software. The software will generates the S.D. scores and percentile (...) the sensory processing abilities of children between the ages of three and 12 years. Score each response according to the following criteria:1. Always = 1 point; 2. Frequently = 2 points; 3. Occassionally = 3 points; 4. Seldom = 4 points; 5. Never = 5 points.To determine the section raw score total, add the item scores for each section and transfer the total to the section summary table. Plot the child's section raw score totals in the classification column corresponding to the raw score total for each

2018 Clinical Trials

132. Rhythm and Multisensoriality's Effects on the Motor Development in Children With Cerebral Palsy

in front of a computer, seating comfortably on a chair during 1 hour. The experimental task consists in learning a sequence of taps on "Serial reaction time task" type buzzers (SRTT) in which the child must press a buzzer corresponding to one of the 4 squares that on the screen. The sequence corresponds to 10 steps in a particular order. Condition or disease Intervention/treatment Phase Cerebral Palsy Other: luminous stimuli Not Applicable Detailed Description: Cerebral palsy (CP) affects the motor (...) function but also the cognitive function of the child. Physical activity brings motor and cognitive benefits and appears as an important aspect of the therapy that is offered to them. In particular, the learning of movements in the presence of multisensory rhythmic information seems to have beneficial effects at the cognitive and motor level. The present study aims to test the respective effects of rhythm and multisensoriality on motor learning in children with cerebral palsy. The motor learning task

2018 Clinical Trials

133. Immersive Virtual Reality to Reduce Procedural Pain During IV Insertion in Children in the Emergency Department

in the pediatric emergency department. The study will consist of two study arms, where both study arms will be screened and recruited using the same procedure. Participants will be randomized into either (1) Control group: child life specialist plays an age-appropriate video on a tablet device, or (2) Intervention (VR Distraction): child life specialist facilitates immersive VR experience. Both the intervention and control groups will receive standard medical care (e.g., topical anesthetics). A convenience (...) Identifier: NCT03435367 Recruitment Status : Recruiting First Posted : February 16, 2018 Last Update Posted : July 20, 2018 See Sponsor: The Hospital for Sick Children Information provided by (Responsible Party): Jennifer Stinson, The Hospital for Sick Children Study Details Study Description Go to Brief Summary: Venipuncture and intravenous (IV) access continue to be the most common causes of pain and distress among children in the pediatric emergency department. Virtual reality has been successful

2018 Clinical Trials

134. Universal newborn hearing screening - methods and results, obstacles and benefits Newborn hearing screening. Full Text available with Trip Pro

used primarily include automated auditory brainstem responses and otoacoustic emissions that provide noninvasive recordings of physiologic auditory activity and are easily performed in neonates and infants. The aim of this review is to present the objectives, benefits, and results of newborn hearing screening programs including the pros and cons of universal vs. selective screening. A brief history and the anticipated future development of these programs will also be discussed. (...) Universal newborn hearing screening - methods and results, obstacles and benefits Newborn hearing screening. The incidence of sensorineural hearing loss ranges from 1 to 3 per 1,000 live births in term healthy neonates, and 2-4 per 100 in high-risk infants, a 10-fold increase. Early identification and intervention with hearing augmentation within 6 mo yields optimal effect. If undetected and without treatment, significant hearing impairment may negatively impact speech development and lead

2016 Pediatric Research

135. Newborn hearing screening at a community-based obstetric unit: Screening and diagnostic outcomes. Full Text available with Trip Pro

Newborn hearing screening at a community-based obstetric unit: Screening and diagnostic outcomes. Postnatal visits at community-based midwife obstetric units (MOUs) have been proposed as an alternative primary healthcare screening platform in South Africa. This study evaluated the outcomes of distortion product otoacoustic emissions (DPOAEs) and automated auditory brainstem response (AABR) screening conducted by a dedicated non-professional screener at a community-based MOU in the Western Cape (...) , South Africa.Universal newborn hearing screening (UNHS) at a community-based MOU was evaluated over a 16-month period. A dedicated non-professional screener was trained to follow a two-stage screening protocol targeting bilateral hearing loss. A two group comparative design was used alternating AABR (Maico MB11 BERAphone™()) and DPOAE (Bio-logic AuDX I) technology on a daily basis. Infants referring the initial screen received a follow-up appointment in two days' time and were rescreened

2016 International Journal of Pediatric Otorhinolaryngology

136. ACC/AAP/AHA/ASE/HRS/SCAI/SCCT/SCMR/SOPE 2014 Appropriate Use Criteria for Initial Transthoracic Echocardiography in Outpatient Pediatric Cardiology

- tients without previously known heart disease. The de?- nitions for frequently used terminology in outpatient pediatric cardiology were established using published guidelines and standards and expert opinion. These AUC serve as a guide to help clinicians in the care of children with possible heart disease, speci?cally in terms of when a transthoracic echocardiogram is warranted as an initial diagnostic modality in the outpatient setting. They are also a usefultoolfor educationand provide the Campbell (...) with an echocardiogram. The current document presumes that the clinician has made every effort to determine whether the murmur is inno- cent or not prior to considering the use of an echocar- diogram (21,31). Echocardiographic screening for presumablyor clearlyinnocent murmur hasbeen rated as Rarely Appropriate in this document. This rating is sup- ported by prior publications reporting that examination Campbell et al. JACC VOL. -,NO. -,2014 AUC for Pediatric Echocardiography -,2014:-–- 14 Downloaded From: http

2014 Society for Cardiovascular Angiography and Interventions

137. Tinnitus in Children Practice Guidance

Pure Tone Audiogram/Audiometry SENCO Special Educational Needs Co-ordinator VAS Visual Analogue Scale Terminology!! Abbreviations 4• Tinnitus is a common experience in childhood. • The evidence base on paediatric tinnitus is scarce. In view of this, the underlying principles of managing adult tinnitus are applied to the management of children with tinnitus. However the aetiology, presentation and management of the child’s tinnitus needs to take into account the child’s age, cognitive and linguistic (...) Auditory Processing Disorder ASD Autistic Spectrum Disorder AVM Audiovestibular Medicine BSA British Society of Audiology BTA British Tinnitus Association CAMHS Child and Adolescent Mental Health Service CBT Cognitive Behavioural Therapy ENT Ear, Nose and Throat GP General Practitioner IEP Individual Educational Plan IHP Individual Hearing Pro?le LDLs Loudness Discomfort Levels LIFE Listening Inventory for Education Ef?ciency PINCHE Policy Interpretation Network on Children’s Health and Environment PTA

2015 British Society of Audiology

138. Outcomes with OAE and AABR screening in the first 48h-Implications for newborn hearing screening in developing countries. Full Text available with Trip Pro

Outcomes with OAE and AABR screening in the first 48h-Implications for newborn hearing screening in developing countries. Early discharge of newborns (<24h after birth) from birthing centres is an important barrier to successful newborn hearing screening (NHS) in developing countries. This study evaluated the outcome of NHS within the first 48 h using an automated auditory brainstem response (AABR) device without the need for costly disposables typically required, and transient evoked (...) otoacoustic emissions (TEOAE).NHS was performed on 150 healthy newborns (300 ears) with TEOAE and AABR techniques before discharge at a hospital. A three-stage screening protocol was implemented consisting of an initial screen with TEOAE (GSI AUDIOscreener+) and AABR (BERAphone(®) MB 11). Infants were screened at several time points as early as possible after birth. Infants were only re-screened if either screening technique (TEOAE or AABR) initially yielded a refer outcome. The same audiologist performed

2015 International Journal of Pediatric Otorhinolaryngology

139. Developmental and Functional Outcomes in Children with a Positive Newborn Screen for Krabbe Disease: A Pilot Study of a Phone-Based Interview Surveillance Technique. (Abstract)

with follow-up compared with formal neuropsychological testing.Infants with low galactocerebrosidase activity (as detected by the New York State newborn screening program) were eligible for this longitudinal prospective cohort study. Consenting families were interviewed by telephone at infant ages of 4, 8, 12, 18, and 24 months. Designated instruments were the Ages and Stages Questionnaires, the Clinical Linguistic and Auditory Milestone Scale, the Gross Motor Quotient, the Warner Initial Developmental (...) of Infant and Toddler Development, Third Edition assessments; all their scores were in the normal range.This telephone-based technique allows close monitoring of the developmental and functional status of children with a positive newborn screen for this neurometabolic disease, with special attention to detecting plateauing or regression of developmental milestones. Compliance is improved compared with formal neuropsychological testing.Copyright © 2012 Mosby, Inc. All rights reserved.

2012 Journal of Pediatrics

140. Tympanostomy Tubes in Children Full Text available with Trip Pro

may be attributable to OME, that might otherwise have been overlooked (Statement 4). The degree of hearing impairment is based primarily on the accurate measurement of hearing thresholds and secondarily by parent/caregiver and school (teacher) reports describing the perceived hearing ability of the child. The American Academy of Pediatrics identified several key points relevant to hearing assessment in children, which, although not related exclusively to OME, are worthy of summary here: Any (...) 14Cochrane IBD Review Group, London, Ontario, Canada by this author for this author , , APRN 15 15Connecticut Pediatric Otolaryngology, Yale University School of Medicine, New Haven, Connecticut, USA by this author for this author , , MD 16 16Department of Otolaryngology—Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, USA by this author for this author , , MD 17 17Trisomy 21 Program, Developmental Behavioral Pediatrics, Children’s Hospital of Philadelphia, Philadelphia

2013 American Academy of Otolaryngology - Head and Neck Surgery

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