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Parietal Lobe

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141. Parietal Lobes in Schizophrenia: Do They Matter? Full Text available with Trip Pro

Parietal Lobes in Schizophrenia: Do They Matter? Objective. Despite observations that abnormal parietal lobe (PL) function is associated with psychotic-like experiences, our knowledge about the nature of PL involvement in schizophrenia is modest. The objective of this paper is to investigate the role of the PL in schizophrenia. Method. Medline databases were searched for English language publications using the following key words: parietal lobe, combined with schizophrenia, lesions, epilepsy (...) , cognition, rare genetic disorders, MRI, fMRI, PET, and SPECT, respectively, followed by cross-checking of references. Results. Imaging studies in childhood onset schizophrenia suggest that grey matter abnormalities start in parietal and occipital lobes and proceed to frontal regions. Although, the findings are inconsistent, several studies with patients at risk to develop schizophrenia indicate early changes in the PL. Conclusions. We want to propose that in a proportion of individuals with emerging

2011 Schizophrenia Research and Treatment

142. Neuronal Chains for Actions in the Parietal Lobe: A Computational Model Full Text available with Trip Pro

Neuronal Chains for Actions in the Parietal Lobe: A Computational Model The inferior part of the parietal lobe (IPL) is known to play a very important role in sensorimotor integration. Neurons in this region code goal-related motor acts performed with the mouth, with the hand and with the arm. It has been demonstrated that most IPL motor neurons coding a specific motor act (e.g., grasping) show markedly different activation patterns according to the final goal of the action sequence in which (...) the act is embedded (grasping for eating or grasping for placing). Some of these neurons (parietal mirror neurons) show a similar selectivity also during the observation of the same action sequences when executed by others. Thus, it appears that the neuronal response occurring during the execution and the observation of a specific grasping act codes not only the executed motor act, but also the agent's final goal (intention).In this work we present a biologically inspired neural network architecture

2011 PloS one

143. Recency Effects in the Inferior Parietal Lobe during Verbal Recognition Memory Full Text available with Trip Pro

Recency Effects in the Inferior Parietal Lobe during Verbal Recognition Memory The most recently encountered information is often most easily remembered in psychological tests of memory. Recent investigations of the neural basis of such "recency effects" have shown that activation in the lateral inferior parietal cortex (LIPC) tracks the recency of a probe item when subjects make recognition memory judgments. A key question regarding recency effects in the LIPC is whether they fundamentally (...) maintenance. We conclude with a discussion of two alternative explanations - the memory strength and "expectancy" hypotheses, respectively - of the parietal lobe recency effect.

2011 Frontiers in human neuroscience

144. Alterations in regional homogeneity of resting-state brain activity in mesial temporal lobe epilepsy. Full Text available with Trip Pro

Alterations in regional homogeneity of resting-state brain activity in mesial temporal lobe epilepsy. The purpose of the present study was to identify abnormal areas of regional synchronization in patients with mesial temporal lobe epilepsy and hippocampus sclerosis (mTLE-HS) compared to healthy controls, by applying a relatively novel method, the Regional Homogeneity (ReHo) method to resting state fMRI (RS-fMRI) data.Eyes closed RS-fMRI data were acquired from 10 mTLE-HS patients (four right (...) structures, whereas decreased ReHo was observed mainly in default mode network (DMN) (including precuneus and posterior cingulate gyrus, bilateral inferior lateral parietal, and mesial prefrontal cortex) and cerebellum in patients relative to the control group.This study identified that ReHo pattern in mTLE-HS patients was altered compared to healthy controls. We consider decreased ReHo in DMN to be responsible for wide functional impairments in cognitive processes. We propose that the increased ReHo

2013 Epilepsia

145. Temporal lobe volume abnormalities precede the prodrome: a study of children presenting antecedents of schizophrenia. Full Text available with Trip Pro

-middle temporal gyri (P < 0.05, cluster correction). WM volume was significantly increased in ASz children relative to TD children in a cluster encompassing the left inferior parietal lobe, occipital lobe, and superior temporal gyrus. Post-hoc analyses indicated that these abnormalities were not limited to ASz children who self-reported auditory hallucinations on questionnaire. Our findings suggest that children aged 9-12 years who present multiple ASz are characterized by abnormalities of GM and WM (...) Temporal lobe volume abnormalities precede the prodrome: a study of children presenting antecedents of schizophrenia. Distributed abnormalities of gray matter (GM) and white matter (WM) volume characterize individuals experiencing their first episode of schizophrenia. Regions of abnormality are present already, albeit less extensively, during the prodromal phase of illness. This study aimed to determine whether putatively at-risk children, aged 9-12 years, who present multiple antecedents

2013 Schizophrenia bulletin

146. Viral and paraneoplastic encephalitis in a patient with liver transplant with unilateral temporoparietal lobe abnormalities: a diagnostic challenge Full Text available with Trip Pro

Viral and paraneoplastic encephalitis in a patient with liver transplant with unilateral temporoparietal lobe abnormalities: a diagnostic challenge We report a patient who recently had a liver transplant presented with increasing confusion and intermittent hallucinations. MRI of the brain revealed diffuse left temporal and parietal lobe swelling with cortical diffusion restriction suggestive of possible infectious aetiology, although stroke was also possible given the presence of left posterior

2013 BMJ case reports

147. Disrupted segregation of working memory networks in temporal lobe epilepsy Full Text available with Trip Pro

left) and 30 healthy controls underwent working memory functional MRI (fMRI) and Diffusion Tensor Imaging (DTI). Six seed regions were identified for FC analysis; 4 within a task-positive network (left and right middle frontal gyri and superior parietal lobes), and 2 within a task-negative network (left and right hippocampi). FC maps were created by extracting the time-series of the fMRI signal in each region in each subject and were used as regressors of interest for additional GLM fMRI analyses (...) . Structural connectivity (SC) corresponding to areas to which the left and right hippocampi were connected was determined using tractography, and a mean FA for each hippocampal SC map was calculated. Both left and right HS groups showed atypical FC between task-positive and task-negative networks compared to controls. This was characterised by co-activation of the task-positive superior parietal lobe ipsilateral to the typically task-negative sclerosed hippocampus. Correlational analysis revealed stronger

2013 NeuroImage : Clinical

148. Abnormal activation of the occipital lobes during emotion picture processing in major depressive disorder patients Full Text available with Trip Pro

. Moreover, the consistency for recognizing pictures for depressed patients was worse than normal controls, and they frequently recognized positive pictures as negative pictures. The consistency for recognizing pictures was negatively correlated with the Hamilton Depression Rating Scale. Functional MRI suggested that the activation of some areas in the frontal lobe, temporal lobe, parietal lobe, limbic lobe, and cerebellum was enhanced, but that the activation of some areas in the frontal lobe, parietal (...) lobe and occipital lobe was weakened while the patients were watching positive and neutral pictures compared with normal controls. The activation of some areas in the frontal lobe, temporal lobe, parietal lobe, and limbic lobe was enhanced, but the activation of some areas in the occipital lobe were weakened while the patients were watching the negative pictures compared with normal controls. These findings indicate that patients with major depressive disorder have negative cognitive disorder

2013 Neural Regeneration Research

149. Presurgical connectome and postsurgical seizure control in temporal lobe epilepsy. Full Text available with Trip Pro

thalamocortical regions, with a pathologic increase in ipsilateral medial temporal lobe, insular, and frontal connectivity. Among patients, those not seizure-free exhibited a higher connectivity between structures in 1) the ipsilateral medial and lateral temporal lobe, 2) the ipsilateral medial temporal and parietal lobe, and 3) the contralateral temporal pole and parietal lobe. Patients not seizure-free also exhibited lower small-worldness in the subnetwork within the ipsilateral temporal lobe, with higher (...) Presurgical connectome and postsurgical seizure control in temporal lobe epilepsy. The objective of this study was to evaluate whether patients with surgically refractory medial temporal lobe epilepsy (MTLE) exhibit a distinct pattern of structural network organization involving the temporal lobes and extratemporal regions.We retrospectively studied 18 healthy controls and 20 patients with medication refractory unilateral MTLE who underwent anterior temporal lobectomy for treatment of seizures

2013 Neurology

150. Occipital Lobe

is the one of five lobes of the cerebral hemisphere which occupies the posterior-most portion of the hemisphere. Anteriorly, it shares an arbitrary border with the parietal lobe and temporal lobe. Medially, it is bounded by the longitudinal cerebral fissure. Definition (NCI) The posterior part of the cerebral hemisphere. (MeSH) Definition (NCI_CDISC) The posterior part of the cerebral hemisphere. (MeSH) Definition (MSH) Posterior portion of the CEREBRAL HEMISPHERES responsible for processing visual (...) Occipital Lobe Occipital Lobe Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Occipital Lobe Occipital Lobe Aka: Occipital Lobe

2015 FP Notebook

151. Temporal Lobe

border shared with the occipital lobe. Definition (CHV) the lower lateral lobe of either cerebral hemisphere Definition (CHV) the lower lateral lobe of either cerebral hemisphere Definition (CHV) the lower lateral lobe of either cerebral hemisphere Definition (CHV) the lower lateral lobe of either cerebral hemisphere Definition (NCI_CDISC) Lower lateral part of the cerebral hemisphere. (MSH2001) Definition (NCI) One of the cerebral lobes. It is located inferior to the frontal and parietal lobes (...) Temporal Lobe Temporal Lobe Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Temporal Lobe Temporal Lobe Aka: Temporal Lobe , Temporal

2015 FP Notebook

152. Frontal Lobe

window. Related Studies (from Trip Database) Ontology: frontal lobe (C0016733) Definition (FMA) Frontal lobe is the anterior-most of five lobes of the cerebral hemisphere. It is bounded by the central sulcus on its posterior border and by the longitudinal cerebral fissure on its medial border. Definition (NCI) The part of the brain located anterior to the parietal lobes at the front of each cerebral hemisphere. Definition (NCI_CDISC) The part of the brain located anterior to the parietal lobes (...) Frontal Lobe Frontal Lobe Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Frontal Lobe Frontal Lobe Aka: Frontal Lobe , Cerebral

2015 FP Notebook

153. Interhemispheric temporal lobe connectivity predicts language impairment in adolescents born preterm. Full Text available with Trip Pro

with bilateral volume reductions in the ventral language pathway. However, the most significant volume reduction was detected in the posterior corpus callosum (splenium), which contains interhemispheric connections between the occipital, parietal and temporal lobes. Diffusion tractography showed that of the three groups of interhemispheric fibres within the splenium, only those connecting the temporal lobes were reduced. Crucially, we found that language impairment was only detectable if the anterior (...) Interhemispheric temporal lobe connectivity predicts language impairment in adolescents born preterm. Although language difficulties are common in children born prematurely, robust neuroanatomical correlates of these impairments remain to be established. This study investigated whether the greater prevalence of language problems in preterm (versus term-born) children might reflect injury to major intra- or interhemispheric white matter pathways connecting frontal and temporal language regions

2012 Brain

154. Brain structure and aging in chronic temporal lobe epilepsy. Full Text available with Trip Pro

of cortical gray matter thickness, area, or volume in temporal (medial, lateral) and extratemporal lobes (frontal, parietal). Increasing chronologic age was associated with progressive changes in diverse cortical, subcortical, and cerebellar regions for both participants with epilepsy and controls. Age-accelerated changes in epilepsy participants were seen in selected areas (third and lateral ventricles), with largely comparable patterns of age-related change across other regions of interest.Extensive (...) Brain structure and aging in chronic temporal lobe epilepsy. To characterize differences in brain structure and their patterns of age-related change in individuals with chronic childhood/adolescent onset temporal lobe epilepsy compared with healthy controls.Subjects included participants with chronic temporal lobe epilepsy (n = 55) of mean childhood/adolescent onset and healthy controls (n = 53), age 14-60 years. Brain magnetic resonance imaging (MRI) studies (1.5 T) were processed using

2012 Epilepsia

155. Spectral and spatial shifts of post-ictal slow waves in temporal lobe seizures. Full Text available with Trip Pro

. These results revealed that a widespread cortical network including temporal and fronto-parietal cortex is involved in abnormal slow-wave activity following temporal lobe seizures. The differential spectral and spatial shifts of post-ictal electroencephalography activity in simple partial, complex partial and secondarily generalized seizures suggest a possible connection between cortical slow waves and behavioural and cognitive changes in a human epilepsy model. (...) Spectral and spatial shifts of post-ictal slow waves in temporal lobe seizures. Temporal lobe seizures have a significant chance to induce impairment of normal brain functions. Even after the termination of ictal discharges, during the post-ictal period, loss of consciousness, decreased responsiveness or other cognitive dysfunctions can persist. Previous studies have found various anatomical and functional abnormalities accompanying temporal lobe seizures, including an abnormal elevation

2012 Brain

156. Psychopathology in children before and after surgery for extratemporal lobe epilepsy. (Abstract)

Psychopathology in children before and after surgery for extratemporal lobe epilepsy. To establish the rates and types of psychiatric disorder in children before and after surgery for extratemporal epilepsy. Relationships between psychiatric morbidity and demographic/clinical variables were examined.A retrospective case note review of 71 children undergoing extratemporal focal resection for drug resistant epilepsy in a specialist epilepsy surgery programme between 1997 and 2008. Psychiatric (...) diagnoses were derived from pre- and postoperative assessments according to DSM-IV criteria.Seventy-one children (38 males, 33 females) were eligible for this study. Mean age (SD) at surgery was 9 (5) years. Frontal resections were performed in 73% of the children, parietal in 17%, and occipital in 10%. Mental health problems were present in 37 of 71 (52%) children pre- and/or postoperatively. A similar proportion of children had psychiatric diagnoses pre- and postoperatively: 31 of 71 (44%) and 32

2012 Developmental Medicine and Child Neurology

157. Facilitating Associative Memory Via Deep Transcranial Magnetic Stimulation to the Medial Temporal Lobe

Facilitating Associative Memory Via Deep Transcranial Magnetic Stimulation to the Medial Temporal Lobe Facilitating Associative Memory Via Deep Transcranial Magnetic Stimulation to the Medial Temporal Lobe - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please (...) remove one or more studies before adding more. Facilitating Associative Memory Via Deep Transcranial Magnetic Stimulation to the Medial Temporal Lobe The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT01599208 Recruitment Status : Withdrawn (no IRB) First Posted : May 15, 2012 Last Update Posted

2012 Clinical Trials

158. Changes in the default mode network in the prefrontal lobe, posterior cingulated cortex and hippocampus of heroin users Full Text available with Trip Pro

Changes in the default mode network in the prefrontal lobe, posterior cingulated cortex and hippocampus of heroin users The default mode network is associated with senior cognitive functions in humans. In this study, we performed independent component analysis of blood oxygenation signals from 14 heroin users and 13 matched normal controls in the resting state through functional MRI scans. Results showed that the default mode network was significantly activated in the prefrontal lobe, posterior (...) cingulated cortex and hippocampus of heroin users, and an enhanced activation signal was observed in the right inferior parietal lobule (P < 0.05, corrected for false discovery rate). Experimental findings indicate that the default mode network is altered in heroin users.

2012 Neural Regeneration Research

159. The Riddoch phenomenon revealed in non-occipital lobe lesions. Full Text available with Trip Pro

Optic Atrophy complications Parietal Lobe Visual Acuity Visual Field Tests Visual Fields 1971 6 1 1971 6 1 0 1 1971 6 1 0 0 ppublish 5090280 PMC1208387 Doc Ophthalmol. 1969;26:215-29 5359517 Am J Ophthalmol. 1970 Sep;70(3):403-22 5450849 Brain. 1953;76(4):515-50 13115572 (...) The Riddoch phenomenon revealed in non-occipital lobe lesions. 5090280 1971 08 13 2018 11 13 0007-1161 55 6 1971 Jun The British journal of ophthalmology Br J Ophthalmol The Riddoch phenomenon revealed in non-occipital lobe lesions. 416-20 Zappia R J RJ Enoch J M JM Stamper R R Winkelman J Z JZ Gay A J AJ eng Journal Article England Br J Ophthalmol 0421041 0007-1161 IM Adult Brain Diseases Carotid Artery Diseases complications Female Hemianopsia Humans Male Methods Middle Aged Occipital Lobe

1971 The British journal of ophthalmology

160. Lower effective connectivity between amygdala and parietal regions in response to fearful faces in schizophrenia. (Abstract)

of the precuneus and parietal lobe, compared to healthy controls. These regions have been associated with emotion processing and high level social cognition tasks involving self related processing and mental representations about other people. The reduced amygdala connectivity in schizophrenia shown here further illuminates the neural basis for the behavioral abnormalities in emotional and social function found in the disorder.Copyright © 2010 Elsevier B.V. All rights reserved. (...) Lower effective connectivity between amygdala and parietal regions in response to fearful faces in schizophrenia. Behavioral abnormalities related to processing negative emotions such as fear have been demonstrated in schizophrenia. The amygdala is strongly associated with fear processing, and alterations in amygdala function and structure have been demonstrated in schizophrenia. Further, functional disconnectivity has been attributed as key to the etiology of schizophrenia, with a number

2011 Schizophrenia Research

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