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Papule

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3581. Purple-red papules on foot. (Abstract)

Purple-red papules on foot. An 88-year-old Caucasian man of Italian ancestry came into our clinic with multiple, painful purple-red "growths" on his left foot that he'd had for several years. The patient had no systemic complaints (no fever, chills, weight loss, night sweats). He had a history of hypertension, a cardiac valve replacement, and chronic back pain (secondary to a motor vehicle accident). He was taking warfarin and nadolol. The patient had multiple, 0.1- to 0.5-cm purple-red papules

2008 Journal of Family Practice

3582. Multiple papules and nodules on the face and neck caused by the larvae of an unknown nematode: A noncreeping type eruption. (Abstract)

Multiple papules and nodules on the face and neck caused by the larvae of an unknown nematode: A noncreeping type eruption. Cutaneous larva migrans is caused by various nematodes. Skin manifestations may include superficial or creeping eruptions, folliculitis, and migratory subcutaneous nodules. We report a 52-year-old man with asymptomatic, multiple eruptive papules and nodules on the face and neck caused by the larvae of an unknown nematode. The patient never had any creeping or migratory

2008 Journal of American Academy of Dermatology

3583. Late-onset Epstein-Barr virus-negative post-transplant lymphoproliferative disorder presenting as ulcerated necrotic papules and nodules in a renal transplant patient. (Abstract)

Late-onset Epstein-Barr virus-negative post-transplant lymphoproliferative disorder presenting as ulcerated necrotic papules and nodules in a renal transplant patient. We report a case of B-cell post-transplant lymphoproliferative disorder in a 57-year-old female 19 years postrenal transplant patient who presented with multiple, progressive, painful ulcerated necrotic papules and nodules over the left leg. Histopathological examination showed diffuse infiltration of the dermis by large atypical

2008 Australasian Journal of Dermatology

3584. Fibrous papule of the face with granular cells. (Abstract)

Fibrous papule of the face with granular cells. Fibrous papule of the face is a common benign lesion located most often on the nose. It presents usually as a single small, firm, skin-coloured papule and is often misdiagnosed as melanocytic naevus, wart or small nodular basal cell carcinoma. Histopathologically, the lesions are characterized by involvement of the upper dermis by a fibrovascular proliferation and scattered triangular or stellate, often multinucleated cells. Uncommon (...) histopathologic variants of fibrous papule of the face include hypercellular, clear-cell, pleomorphic, pigmented, inflammatory and granular-cell types. We present here a patient with the syndrome of familial cancer and fibrous papule of the face with granular cells. The granules stained strongly with PAS stain, as well as with CD68 and NKI/C3 immunostains, whereas S-100 protein resulted negative. In our patient the mutations in the 2 most often affected DNA mismatch repair genes of Muir-Torre syndrome were

2008 Dermatology

3585. Sirolimus-Induced Inflammatory Papules with Acquired Reactive Perforating Collagenosis. (Abstract)

Sirolimus-Induced Inflammatory Papules with Acquired Reactive Perforating Collagenosis. Sirolimus is an immunosuppressive macrolide with antineoplasic properties that is increasingly used in posttransplantation immunosuppression. The treatment is frequently associated with cutaneous side effects such as sirolimus-associated acneiform facial dermatitis, which has been observed in up to 50% of treated patients. We report a 51-year-old female with liver transplantation who developed inflammatory (...) papules and nodules on the face and the upper chest 3 weeks after the initiation of sirolimus therapy. Sequential biopsies revealed lymphocytic infiltration of the dermis with a peculiar pattern of sebotropism, while older lesions showed acquired reactive perforating collagenosis. The lesions were responsive to hydroxychloroquine treatment despite continued sirolimus treatment.

2008 Dermatology

3586. Mucocutaneous papillomatous papules in Cowden's syndrome. (Abstract)

Mucocutaneous papillomatous papules in Cowden's syndrome. Cowden syndrome (CS; also known as multiple hamartoma syndrome) is a rare autosomal dominant disorder characterized by multiple hamartomas and a high risk of development of thyroid, breast, endometrial and other cancers. The cardinal features of the disease, which often lead to diagnosis, include mucocutaneous papillomatous papules and trichilemmomas. Most affected people develop these characteristic lesions by the age of 20 years. Once

2007 Clinical & Experimental Dermatology

3587. Pruritus, papules, and perspiration. (Abstract)

Pruritus, papules, and perspiration. The development of pruritus and papules with increased body temperature is a common clinical scenario seen in allergy practice, often leading to a diagnosis of cholinergic urticaria.To describe an unusual case of miliaria and its significance in the evaluation of patients with pruritic papular eruptions that occur with increased body temperature.An 18-year-old woman was referred to a local allergist for the evaluation of cholinergic urticaria

2007 Asthma & Immunology

3588. The solitary lymphomatous papule, nodule, or tumor. (Abstract)

The solitary lymphomatous papule, nodule, or tumor. Lymphoma and reactive lymphoid infiltrates presenting as solitary lesion pose a diagnostic and prognostic dilemma for the clinician.We sought to review prognosis and treatment of suggestive solitary lymphoma lesions.A retrospective chart review was conducted in 27 patients who presented with a single solitary lesion suggestive of lymphoma at a cancer center.Eighteen of 27 patients' (66.7%) lesions were diagnosed as lymphoma by histology

2007 Journal of American Academy of Dermatology

3589. Pruritic urticarial papules and plaques of pregnancy presenting in the postpartum period: a case report. (Abstract)

Pruritic urticarial papules and plaques of pregnancy presenting in the postpartum period: a case report. Pruritic urticarial papules and plaques of pregnancy (PUPPP), also known as polymorphic eruption of pregnancy, is the most common dermatosis of pregnancy. It usually evolves in the third trimester and resolves rapidly postpartum.A 25-year-old woman complained of an intensely pruritic rash for 2 days. The rash began 10 days postpartum. It began on her abdomen and spread to her buttocks, legs (...) and upper arms. On examination, erythematous papules and urticarial plaques were present in the striae of the abdomen and buttocks and involved the legs, arms and back. No excoriations, vesicles or pustules were present, and there was sparing of the face, palms and soles. The patient was treated with fexofenadine, hydroxyzine, oatmeal baths and cool compresses. Follow-up 2 days later revealed a worsening rash and persistence of severe pruritus. At that time the patient was placed on prednisone, which

2005 Journal of Reproductive Medicine

3590. Pruritic urticarial papules and plaques of pregnancy with unusual and extensive palmoplantar involvement. (Abstract)

Pruritic urticarial papules and plaques of pregnancy with unusual and extensive palmoplantar involvement. Pruritic urticarial papules and plaques of pregnancy (PUPPP) is a specific dermatosis of pregnancy common to primigravid women in the third trimester. The rash usually begins on the lower abdomen within striae and spreads to the proximal extremities. Involvement of face, palms, and soles is unusual. Although intensely pruritic, the fetus is unaffected, and the condition does not usually (...) , with small vesicles of 2-4 mm on acral skin. Because of her unusual presentation, she was thought initially to have pemphigoid gestationis. Subsequent dermatological evaluation and a biopsy confirmed the diagnosis of PUPPP. Shortly after admission she delivered 2 healthy male infants, and her rash cleared with conservative management.Pruritic urticarial papules and plaques of pregnancy often, but not always, spares the face, palms, and soles. Small vesicles can occur in PUPPP, but formation of true

2005 Obstetrics and Gynecology

3591. Fractional Resurfacing for the Treatment of Pearly Penile Papules. (Abstract)

Fractional Resurfacing for the Treatment of Pearly Penile Papules. 18657165 2008 12 10 2008 12 01 1524-4725 34 10 2008 Oct Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] Dermatol Surg Fractional resurfacing for the treatment of pearly penile papules. 1420-2; discussion 1422 10.1111/j.1524-4725.2008.34300.x Rokhsar Cameron K CK Albert Einstein College of Medicine, New York, New York 10021, USA. crokhsar@yahoo.com Ilyas Humza H eng Case Reports

2008 Dermatologic Surgery

3592. Benign lymphangiomatous papules of the skin. (Abstract)

Benign lymphangiomatous papules of the skin. Benign lymphangiomatous papules of the skin are benign lymphatic proliferations that may arise in the skin after operation or radiation therapy. We report a case of benign lymphangiomatous papules of the skin that occurred in a patient 4 years after undergoing radiation therapy to the chest for adenocarcinoma of the breast.

2005 Journal of American Academy of Dermatology

3593. Histopathology of persistent papules and plaques in adult-onset Still's disease. (Abstract)

Histopathology of persistent papules and plaques in adult-onset Still's disease. Persistent plaques and linear pigmentation have been reported as specific skin lesions in some patients with adult-onset Still's disease (AOSD).We sought to characterize the histologic findings of AOSD-associated persistent rash in 11 cases and correlate the histologic findings with the clinical features.From 1988 to 2004, 17 cases fulfilling Yamaguchi's criteria for AOSD in our hospital were reviewed and 11 (65 (...) %) manifested persistent papules and plaques. The pathology of 13 biopsy specimens of persistent eruption from 9 patients was reviewed.The 11 patients consisted of 3 men and 8 women with age of onset ranging from 19 to 67 years (average 34.7 years). Evanescent Still's rash was recorded in 9 patients. The persistent rash manifested as pruritic, red, violaceous, or brownish scaly or crusted lichenoid papules and plaques usually widely distributed over the trunk, neck, face, and extensor sides

2005 Journal of American Academy of Dermatology

3594. Infantile pedal papules. (Abstract)

Infantile pedal papules. Infantile pedal papules are symmetric, painless, flesh-colored nodules on the medial aspects of an infant's heels. Although the medical literature suggests they are uncommon, a survey of 269 newborns and 189 infants indicates the incidence of these to be 5.9% in newborns and 39.4% in infants.

2005 Journal of American Academy of Dermatology

3595. Erosive papulonodular dermatosis associated with topical benzocaine: a report of two cases and evidence that granuloma gluteale, pseudoverrucous papules, and Jacquet's erosive dermatitis are a disease spectrum. (Abstract)

Erosive papulonodular dermatosis associated with topical benzocaine: a report of two cases and evidence that granuloma gluteale, pseudoverrucous papules, and Jacquet's erosive dermatitis are a disease spectrum. Granuloma gluteale infantum/adultorum, pseudoverrucous papules, and Jacquet's erosive diaper dermatitis are fairly uncommon manifestations of irritant contact dermatitis historically thought to be distinct clinical entities. Here we report two informative cases of an erosive (...) papulonodular dermatosis in the genital and suprapubic area associated with topical benzocaine. We review granuloma gluteale infantum, pseudoverrucous papules and nodules, and Jacquet's erosive diaper dermatitis, and propose that these disorders may all be variants of genitocrural irritant dermatitis.

2006 Journal of American Academy of Dermatology

3596. Benign lymphangiomatous papules of the skin associated with ovarian fibroma. (Abstract)

Benign lymphangiomatous papules of the skin associated with ovarian fibroma. Benign lymphangiomatous papules of the skin are considered reactive lymphatic proliferations either caused by disruption of the lymphatic flow or tissue damage produced by operation or radiation therapy. We report a 72-year-old woman with umbilical papules and vesicle-like lesions that led to the diagnosis of a large ovarian fibroma. Histologic study revealed dilated lymphatic spaces manifesting an anastomosing (...) and branched pattern in the papillary and reticular dermis dissecting collagen bundles. The vessels were lined by plump endothelial cells with foci of intravascular papillary endothelial cell hyperplasia. After the ovarian fibroma was removed by laparotomy, umbilical lesions almost disappeared, leaving small flesh-colored papules. A periumbilical dermatosis may herald certain intra-abdominal diseases including those of neoplastic derivation. A heightened awareness of this association may lead to an early

2007 Journal of American Academy of Dermatology

3597. Whitish papules on the palm. (Abstract)

Whitish papules on the palm. A 21-year-old woman presented with a 1-month history of whitish bubbling of the palms after brief exposure to water. The symptoms arose within 3-5 min after immersion in water, as a white sponge-like appearance, and resolved after a variable drying period. She was otherwise healthy and did not complain of hyperhidrosis. There was no family history of similar lesions. Physical examination revealed a healthy appearance of the palms; however, 5 min after immersion (...) of the hands in warm water, the central part of the left palm became swollen and tiny white papules with dilated puncta appeared. The right palm also showed similar changes. These asymptomatic papules with a tendency to coalesce became more prominent with prolonged exposure (Figs 1 and 2). The lesions resolved completely approximately 30 min after removal of the hands from water. A biopsy taken from the lesional skin revealed dilatation of intraepidermal eccrine ducts and a spongy appearance in the corneal

2007 International Journal of Dermatology

3598. Rheumatoid papules treated with dapsone. (Abstract)

Rheumatoid papules treated with dapsone. A patient with a long history of seropositive rheumatoid arthritis presented with a progressive papular eruption on the trunk. A skin biopsy showed a neutrophilic and palisaded granulomatous dermatitis compatible with rheumatoid papules. The eruption failed to respond to topical and systemic corticosteroids and the patient was treated with dapsone with complete resolution of the rash. Rheumatoid papules are a rare disorder seen in a variety of collagen (...) vascular diseases. The literature concerning the treatment of rheumatoid papules is scanty. In this patient, dapsone was an effective treatment.

2004 Clinical & Experimental Dermatology

3599. The effect of haematopoietic stem cell transplant on papules with 'pebbly' appearance in Hunter's syndrome. (Abstract)

The effect of haematopoietic stem cell transplant on papules with 'pebbly' appearance in Hunter's syndrome. Hunter's syndrome is associated with several cutaneous findings. For instance, papules with 'pebbly' appearance are a specific marker for the disease. However, it remains uncertain whether they disappear after haematopoietic stem cell transplant (HSCT).To investigate the papules with 'pebbly' appearance before and after HSCT in infants with Hunter's syndrome, and to clarify the effect (...) of HSCT on papules.We observed five Japanese boys with Hunter's syndrome who had received HSCT at 4-11 years of age.The post-HSCT physical examinations revealed that papules disappeared completely within 35 days after the transplant with progressive reduction of cutaneous tightness in all the patients. Histochemical findings showed that papules contained a large amount of hyaluronic acid in the extracellular materials of the dermis and sulphated acid mucopolysaccharides in dermal fibroblasts before

2004 British Journal of Dermatology

3600. Pruritic urticarial papules and plaques of pregnancy: current status. (Abstract)

Pruritic urticarial papules and plaques of pregnancy: current status. Pruritic urticarial papules and plaques of pregnancy is a common benign dermatosis of pregnancy that was described in 1979 as an intensely pruritic urticarial cutaneous eruption. This is a well-defined clinical entity that mainly occurs in primigravidas in the third trimester, which resolves spontaneously or with delivery and is usually responsive to topical treatments. The aetiology of PUPPP is obscure. Histology is non

2005 Australasian Journal of Dermatology

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