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181. Genital Skin Lesions (Non-Ulcerative)

be referred for a specialist opinion before any treatment occurs. Normal anatomical variants Males • Pearly penile papules (coronal papillae), Fordyce glands. Females • Vestibular papillomatosis, Fordyce glands Genital warts Exophytic skin lesions that vary in size/shape and number. Males • Typically at leading edge of prepuce, on frenulum, or more sporadically in coronal sulcus, on penile shaft. Less frequently on scrotum or in pubic area or perianal. Females • Usually vulval (often posteriorly

2017 New Zealand Sexual Health Society

183. Lichen Planus

, polygonal violaceous papules localized to the wrists, forearms, distal lower extremities and the pre-sacral area. The lesions on non-keratinised epithelium, such as the buccal mucosa, tongue, esophagus and genitalia are often non-pruritic and may present with burning or being entirely non symptomatic. Mucosal lesions become often erosive. LP affecting the hair follicles and the nail bed will often lead to permanent scarring resulting in islands of alopecia and pterygium formation with eventual loss (...) of the nail plate. 2,14 LP onset is usually acute with initial lesions almost always appearing on the extremities. A generalized eruption, in approximately one-third of the cases, may be developed after one week or more with maximal spreading within 2-16 weeks. Papules are grouped and tend to coalesce and sometimes form a central umbilication. They are usually distributed symmetrically and bilaterally over the extremities and often covered by lacy, reticular, white lines known as Wickham striae. This fine

2018 European Dermatology Forum

184. UK National Guideline for the management of Donovanosis

[8]. Clinical features The first sign of infection is usually a firm papule or subcutaneous nodule that later ulcerates. Four types of donovanosis are described classically [9]: 1) Ulcerogranulomatous is the most common variant; non tender, fleshy, exuberant, single or multiple, beefy red ulcers that bleed readily when touched. 2) Hypertrophic or verrucous type, an ulcer or growth with a raised irregular edge, sometimes with a walnut appearance. 3) Necrotic, usually a deep foul smelling ulcer

2018 British Association for Sexual Health and HIV

185. Soolantra (ivermectin) - inflammatory lesions of papulopustular rosacea

to be high. In addition to metronidazole, azelaic acid 15% gel has previously also been authorised for topical treatment of inflammatory papules and pustules in rosacea. Topical treatment is preferred over systemic treatment because topical treatment is associated with fewer adverse reactions and a lower risk of interactions with concurrent medicinal treatment. Long-term use of antibiotics (including topical treatment) is problematic in relation to development of resistance; therefore alternate treatment

2017 Danish Pharmacotherapy Reviews

186. CRACKCast E191 – Weapons of Mass Destruction

Cutaneous form Spores introduced into the skin (patients already have open wounds or abrasions) After an incubation period of 1 to 5 days, a papule develops, progressing to form a large vesicle during the next several days. Severe edema occurs around the lesion and is associated with regional lymphadenitis. The lesions are not tender, and the patient may or may not be febrile. After approximately 1 week, the lesion ruptures, forming a black eschar (thus the name anthrax, from the Greek word for “coal

2018 CandiEM

187. CRACKCast Episode 183 – The Immunocompromised Patient

Clinical Findings in Neutropenia That May Be Associated with Infection with Specific Pathogens Characteristic Clinical Finding Suspect Pathogens Ulcerative lesions in the mouth Viridans streptococci, herpes simplex, Candida, anaerobes Necrotizing skin lesions Pseudomonas aeruginosa, Aeromonas hydrophila, Aspergillus, Mucor Nontender subcutaneous nodules Nocardia, Cryptococcus Nontender pink skin papules Candida Black eschar of nose or palate Aspergillus, Mucor Generalized macular red rash Viridans

2018 CandiEM

189. Epiduo (adapalene/benzoyl peroxide) 0.3%/2.5% - acne vulgaris

Epiduo (adapalene/benzoyl peroxide) 0.3%/2.5% - acne vulgaris Epiduo® (adapalene/benzoyl peroxide) 0.3%/2.5% × Insert searchphrase to search the website Insert searchphrase to search the website > > > Epiduo® (adapalene/benzoyl peroxide) 0.3%/2.5% Conclusion Epiduo gel is approved for the treatment of acne vulgaris when comedones, several papules and pustules are present. Epiduo contains a combination of the active substances adapalene 3 mg/g (0.3%) and benzoyl peroxide 25 mg/g (2.5

2017 Danish Pharmacotherapy Reviews

190. British Association of Dermatologists' guidelines for the management of lichen sclerosus

symptoms and urinary incontinence are reported by women with LS, 44,45 but have been shown to be less common than inthe general population inanother study. 45,46 The typical lesions are porcelain-white papules and plaques, often associated with areas of ecchymosis. Follicular delling may be prominent, and occasionally hyperkeratosis is a promi- nent feature. The characteristic sites are the interlabial sulci, labia minora, clitoral hood, clitoris and perineal body. LS is a scarring dermatosis and may (...) , ulceration, papule or nodule) should be biopsied. Patients with urinary symptoms should be referred to a urologist for ?ow rate and postvoid residual volume measurement to identify urethral involvement by LS; ultimately, referral to a specialist urologist for management of a urethral stricture or meatal stenosis may be needed. Where medical treatment has failed, patients should be offered referral to discuss other surgical treatment options such as division of coronal adhesions, frenuloplasty and glans

2018 British Association of Dermatologists

191. Shingrix vaccine for herpes zoster

may be preceded by prodromal pain or itching, after which erythematous macules or papules appear. These progress into vesicular lesions, then into pustules. The pustules typically crust over within the course of about ten days. In many patients, the HZ rash heals and painful symptoms resolve entirely within about four weeks. 6 In up to about thirty percent of patients, however, the pain will persist for months beyond the initial rash, known as postherpetic neuralgia (PHN). 3 PHN is conventionally

2018 Therapeutics Letter

193. Inflammatory lesions of papulopustular rosacea: ivermectin 10 mg/g cream

by recurrent episodes of facial flushing, persistent erythema, telangiectasia (fine, dilated blood vessels), papules and pustules. Mild or moderate papulopustular rosacea (with a limited number of papules and pustules, and no plaques) is generally treated with a topical drug (metronidazole or azelaic acid). For moderate or severe papulopustular rosacea (with extensive papules, pustules, or plaques), oral tetracycline, erythromycin, doxycycline or lymecycline can be prescribed, although not all (...) this summary to provide useful information for those working on the managed entry of new medicines for the NHS, but this summary is not NICE guidance but this summary is not NICE guidance. F Full e ull evidence summary vidence summary Introduction and current guidance Rosacea is a chronic relapsing disease of the facial skin, characterised by recurrent episodes of facial flushing, persistent erythema, telangiectasia (fine, dilated blood vessels), papules and pustules. Some people have phymatous rosacea

2016 National Institute for Health and Clinical Excellence - Advice

194. Tinea Corporis Infection - Guidelines for Prescribing Topical Antifungals

in the form of circular scaly pink patches. Can have diffuse inflammation and ill-defined borders - appears as small round plaques of small papules and blisters, usually on arms, neck and legs. Very itchy, can may persist for months - presents as red spots covered with thick silver scales, with no central clearing. Refer to patient's primary care provider - is a viral rash that lasts 6 to 12 weeks, beginning with a "herald" patch: a small, scaly, pink-coloured lesion on the trunk. It starts as a single

2017 medSask

195. Superficial Bacterial Skin Infections - Guidelines for Prescribing Topical Antibiotics for impetigo and folliculitis

itchy, papules and/or pustules at the base of the hair shaft. The causative agent is usually aureus . Furuncles or boils usually begin as folliculitis which spreads and forms a tender, red swelling with a central pustule. This may progress to carbuncles, an aggregate of furuncles which penetrates to deeper layers of skin and can lead to cellulitis, a diffuse inflammation of the skin. Furuncles may require systemic antibiotic treatment. For more information and photos, go to: Less severe form (...) When blister breaks, in 3-5 days, it forms an oozing, yellow crust Areas affected are usually moist diaper areas, armpits and legs Systemic symptoms more likely, such as fever and diarrhea Small red, often itchy, papules and/or pustules at the base of hair shafts especially on neck, groin or armpits Secondary lesions which may follow folliculitis Start as a tender, reddened area or a folliculitis Progress to a hard, tender area with a white pustule at the center The pustule may break open and drain

2017 medSask

196. Diaper Dermatitis, Irritant and Candidal - Guidelines for Prescribing Topical Antifungals and Hydrocortisone

with candida). Satellite papules, and superficial pustules at the margins of the inflammatory plaques. Unlike irritant diaper dermatitis, candida often begins in the creases/skin folds and then extends out to the buttocks and pubic skin. Excoriations are prominent. Often painful - severe crying during diaper changes or when urinating or defecating. Questioning may reveal a history of recent antibiotic use, or a bout of diarrhea, or a case of oral thrush. Diaper dermatitis is diagnosed based on the presence (...) . - 1 to 2 mm fragile pustules and honey-colored, crusted erosions. (Refer to guideline for Bacterial Infections.) - acute, widespread, pruritic dermatitis. Lesions typically occur on the palm, soles or between the fingers. Not a solid rash. - severe rash. Red/orange or yellow/brown scaly papules, erosions, or petchiae. - sharply demarcated erythematous scaly papules and plaques. There may be a family history of psoriasis. Lesions will typically be elsewhere on the body as well. Lack of response

2017 medSask

197. European Dermatology Forum Guideline for the definition, diagnostic testing and management of chronic inducible urticarias

usually starts with small wheals, which may later converge. Provocation testing should be performed to confirm CholU and to rule out exercise-induced anaphylaxis. Caution is advised in patients with pre-existing cardiac conditions. Pretesting examination should be done to record pre-existing skin lesions (e.g. acne papules), which may make assessment more difficult and can be marked with a pen before provocation to identify them. Moderate physical exercise appropriate to the patient’s age and general

2017 European Dermatology Forum

198. Scabies

Maria Salavastru A/Prof. of Dermatology Department of Dermato-pediatry, Colentina Clinical Hospital “Carol Davila” University of Medicine and Pharmacy Bucharest, Romania Str. Dionisie Lupu nr. 37, Sector 2, Bucharest, Romania Tel. 0040213173245 Fax. 0040213186041 Abstract Scabies is caused by Sarcoptes scabiei var. hominis. The disease can be sexually transmitted. Patients’ main complaint is nocturnal itch. Disseminated, excoriated, erythematous papules are usually seen (...) in the infested individual [9]. Human infestation with other S. scabiei variants (e.g. var. canis hosted by dogs and var. suis hosted by pigs) are self-limiting and considered non-transmissible from human to human [10], [11]. Clinical features [12] Specific manifestations include intense itch and disseminated inflammatory papules. Non- specific manifestations which may also occur are skin excoriation, secondary eczematization and impetiginization. 1. Classical scabies [1], [4], [5], [7] -occurs in patients

2017 European Dermatology Forum

199. Herpes Zoster - Diagnosis

. Agius, T. M. Lesser, and J. Sellner. The ?nal recommendations were formally con- sented within the expert panel of the guideline. Generalconsiderations Classically, HZ is a unilateral, dermatomal 18–20 eruption, with skin lesions evolving simultaneously from erythematous macules to papules, vesicles, pustules, and ?nal crusting after about 5– 7 days. Usually not the entire dermatome is involved. Clinical signs include pruritus, paresthesia, dysesthesia or anaesthesia. Local lymphadenopathy may

2017 European Dermatology Forum

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