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161. Scleroderma Morphea

of panniculitis. All differential diagnoses with respect to LS subtypes and stage of disease are summarized in Table 3. Specifics of juvenile localized scleroderma Whereas limited types of LS most commonly occur in adults, linear subtypes predominate in children. A study including 65 patients with juvenile LS revealed that linear subtypes may follow the lines of Blaschko. It was hypothesized that in linear LS, susceptible cells are present in a mosaic state and that exposure to some trigger factors finally (...) ) • Scleromyxedema • Chronic graft versus host disease • Nephrogenic systemic fibrosis, also known as nephrogenic fibrosing dermopathy • Porphyria cutanea tarda Linear localized scleroderma, “en coup de sabre” • Panniculitis • Lupus erythematosus profundus • Progressive lipodystrophy

2018 European Dermatology Forum

165. Primary Cutaneous Lymphomas: ESMO Clinical Practice Guidelines

studies (CT and/or FDG-PET scans) [5]. In PCLs with a predominantly subcutaneous presentation, such as subcutaneous panniculitis-like T cell lymphoma (SPTCL) and primary cutane- ous gamma/delta T cell lymphoma (PCGD-TCL), FDG-PET is essential to evaluate the extent of disease. In patients with typical lymphomatoid papulosis (LyP) or primary cutaneous CD4 þ small/medium T cell lymphoproliferative disorder (LPD), CT and FDG-PET scans are not required. Bone marrow biopsy and V C The Author(s) 2018 (...) disease with patches/?at plaques. In stage IB, Table 1. WHO-EORTC classi?cation for cutaneous lymphomas CutaneousTcelllymphoma Mycosis fungoides (MF) Variants of MF • Folliculotropic MF • Pagetoid reticulosis • Granulomatous slack skin Se ´zary syndrome Primary cutaneous CD30 þ lymphoproliferative disorders • Primary cutaneous anaplastic large cell lymphoma • Lymphomatoid papulosis Subcutaneous panniculitis-like T cell lymphoma Extranodal NK/T cell lymphoma, nasal-type Primary cutaneous peripheral T

2018 European Society for Medical Oncology

166. Lymphoma

? Lymphocyte rich ? Lymphocyte depleted Peripheral T-cell, unspecified Angioimmunoblastic (AITL. formerly AILD) Enteropathy associated T-cell Hepatosplenic T-cell Subcutaneous panniculitis-like Anaplastic large cell (CD30+) ALK+ Anaplastic large cell (CD30+) ALK- Extranodal NK/T-cell, nasal type Special Burkitt lymphoma Intermediate between DLBCL and BL Intermediate between DLBCL and Hodgkin lymphoma B lymphoblastic leukemia/lymphoma B prolymphocytic leukemia Lymphomas associated with HIV infection

2016 CPG Infobase

167. A Case of Sweet's Panniculitis Associated with Spinal Metastasis from Prostate Cancer Full Text available with Trip Pro

A Case of Sweet's Panniculitis Associated with Spinal Metastasis from Prostate Cancer Sweet's panniculitis is a rare variant of Sweet's syndrome in which neutrophilic infiltrate can be found either in the subcutaneous fat or in both the dermis and the subcutaneous tissue. Due to the rarity of this entity, the association between Sweet's panniculitis and malignancies is inconclusive, but cases of Sweet's panniculitis have largely been associated with hematological malignancies. Herein, we (...) present a case of Sweet's panniculitis accompanied by bone metastasis from prostate cancer. Clinicians should be aware that Sweet's panniculitis may be associated with malignancies of solid organs.

2010 Annals of dermatology

168. Eosinophilic Panniculitis and Insect Bite-Like Eruption in a Patient with Chronic Lymphocytic Leukaemia: A Spectrum of the Same Entity Full Text available with Trip Pro

Eosinophilic Panniculitis and Insect Bite-Like Eruption in a Patient with Chronic Lymphocytic Leukaemia: A Spectrum of the Same Entity Background. Eosinophilic dermatosis of hematologic disorders is a reactive process that may cause a variety of clinical manifestations. Methods. We report a patient who had outbreaks of skin lesions since the onset of chronic lymphocytic leukaemia. Results. The cutaneous eruptions began as eosinophilic panniculitis and after changed to insect bite-like lesions (...) . Conclusion. We think that eosinophilic panniculitis and insect bite-like lesions may be part of the spectrum of the same entity in patients with hematologic disorders.

2010 Dermatology research and practice

169. An Autosomal Recessive Syndrome of Joint Contractures, Muscular Atrophy, Microcytic Anemia, and Panniculitis-Associated Lipodystrophy. Full Text available with Trip Pro

An Autosomal Recessive Syndrome of Joint Contractures, Muscular Atrophy, Microcytic Anemia, and Panniculitis-Associated Lipodystrophy. Genetic lipodystrophies are rare disorders characterized by partial or complete loss of adipose tissue and predisposition to insulin resistance and its complications such as diabetes mellitus, hypertriglyceridemia, hepatic steatosis, acanthosis nigricans, and polycystic ovarian syndrome.The objective of the study was to report a novel autosomal recessive (...) nigricans. Two had mild hypertriglyceridemia and all had low levels of high-density lipoprotein cholesterol. Skin biopsy of an erythematous nodular skin lesion from one of the patients revealed evidence of panniculitis. The lipodystrophy initially affected the upper body but later became generalized involving abdomen and lower extremities as well.We conclude that these patients represent a novel autoinflammatory syndrome resulting in joint contractures, muscle atrophy, microcytic anemia

2010 Journal of Clinical Endocrinology and Metabolism

170. PSMB8 Encoding the β5i Proteasome Subunit Is Mutated in Joint Contractures, Muscle Atrophy, Microcytic Anemia, and Panniculitis-Induced Lipodystrophy Syndrome. Full Text available with Trip Pro

PSMB8 Encoding the β5i Proteasome Subunit Is Mutated in Joint Contractures, Muscle Atrophy, Microcytic Anemia, and Panniculitis-Induced Lipodystrophy Syndrome. We performed homozygosity mapping in two recently reported pedigrees from Portugal and Mexico with an autosomal-recessive autoinflammatory syndrome characterized by joint contractures, muscle atrophy, microcytic anemia, and panniculitis-induced lipodystrophy (JMP). This revealed only one homozygous region spanning 2.4 Mb (5818 SNPs

2010 American Journal of Human Genetics

171. Respreeza - human alpha1-proteinase inhibitor

-threatening, chronic pulmonary disease often becomes clinically apparent by the third to fourth decade of life, and usually progresses to severe respiratory insufficiency and premature death. The clinical manifestations may widely vary between patients, and are pulmonary emphysema, liver cirrhosis and, rarely, as the skin disease panniculitis, and is characterized by low serum levels of A1-PI, the main protease inhibitor (PI) in human serum. Type ZZ and SZ A1-PI deficiency are risk factors

2015 European Medicines Agency - EPARs

172. International Consolidated Venous Ulcer Guideline

resulting in fibrosing panniculitis of leg with severe, chronic venous insufficiency). A (Geyer et al., 2004; Navarro et al., 2002; Volikova et al., 2009) CVI= 1.000, High SOR A.2.b.v. Medial lower leg site, with slower healing in ulcers associated with VU location in posterior ankle or back of calf region. A (McGuckin et al., 2002; Pappas et al., 1997; Szewczyk et al., 2009; Yim et al., 2014), CVI= 0.762, High SOR Growth of hair indicates adequate arterial supply and likely VU healing outcome

2015 Association for the Advancement of Wound Care

173. Cellulitis - acute

in the subcutaneous tissues) that occurs as a result of excess accumulation of lymph due to inadequate drainage. Oedema with blisters. Panniculitis — inflammation of subcutaneous adipose tissue. Other conditions include: Drug reaction — characterized by itching and burning. There is usually a well-demarcated area of involvement and a history of similar reaction with prior exposure to the same drug. Necrotizing fasciitis — a destructive and rapidly progressive soft tissue infection that involves the deep

2019 NICE Clinical Knowledge Summaries

175. Istodax for Peripheral T-Cell Lymphoma

subtypes are PTCL Not Otherwise Specified (PTCL NOS), anaplastic large cell lymphoma (ALCL) and angioimmunoblastic T cell lymphoma (AITL). ALCL can be further subclassified based on the presence of ALK expression, which confers a superior prognosis. Other PTCL subtypes include hepatosplenic T-cell lymphoma, enteropathy-associated T-cell lymphoma, subcutaneous panniculitis-like T cell lymphoma, rare subtypes of primary cutaneous T cell lymphoma (not to be confused with mycosis fungoides), and extranodal

2015 Canadian Agency for Drugs and Technologies in Health - Rapid Review

176. Autoimmune Hepatitis

disease, psoriasis, systemic lupus erythematosus, Sjögren’s syndrome, celiac disease, panniculitis, mononeuritis, urticaria pigmentosa, Sweet´s syndrome, idiopathic thrombocytopenic purpura, polymyositis, hemolytic anemia, uveitis) • An unusual form of AIH occurs in 10-18% of patients with APECED - also known as APS-1 AIH, autoimmune hepatitis; PBC, primary biliary cirrhosis; PSC, primary sclerosing cholangitis; AMA, antimitochondrial antibodies; IAIHG, International AIH Group; DILI, drug-induced

2015 European Association for the Study of the Liver

177. Dermatologic Sequelae Associated with Radiation Therapy. (Abstract)

literature review was performed using the Pubmed and Embase databases. Studies were reviewed for relevance and critical evidence pertaining to cutaneous manifestations of radiation therapy. The most commonly reported cutaneous sequelae associated with radiation therapy include radiation dermatitis, non-melanoma skin cancer, radiation-associated angiosarcoma, morphea, bullous pemphigoid, lymphangioma circumscriptum, and pseudosclerodermatous panniculitis. For many of these conditions, only case reports

2020 American journal of clinical dermatology

178. A retrospective review of cutaneous lymphoma in Botswana. (Abstract)

cases of reactive cutaneous processes. Subtypes of cutaneous lymphoma diagnosed included: mycosis fungoides (MF) (81.5%), plasmablastic lymphoma (7.4%), Epstein-Barr virus-positive T-cell lymphoma (3.7%), subcutaneous panniculitis-like T-cell lymphoma (3.7%), and peripheral T-cell lymphoma, not otherwise specified (3.7%). The most common immunohistochemical staining profile in MF cases was CD8 predominance over CD4.Primary cutaneous lymphoma causes significant morbidity and mortality globally. Given

2020 International Journal of Dermatology

179. Genetics of Skin Cancer (PDQ®): Health Professional Version

. The subcutis can be affected by inflammatory conditions such as panniculitis and malignancies such as liposarcoma.[ ] These compartments give rise to their own malignancies but are also the region of immediate adjacent spread of localized skin cancers from other compartments. The boundaries of each skin compartment are used to define the staging of skin cancers. For example, an in situ melanoma is confined to the epidermis. Once the cancer crosses the basement membrane into the dermis, it is invasive

2018 PDQ - NCI's Comprehensive Cancer Database

180. Adult Non-Hodgkin Lymphoma Treatment (PDQ®): Health Professional Version

neoplasms Precursor T-cell neoplasm: precursor T-acute lymphoblastic leukemia/LBL. Peripheral T-cell and NK-cell neoplasms. T-cell CLL/prolymphocytic leukemia. T-cell granular lymphocytic leukemia. Mycosis fungoides (including Sézary syndrome). Peripheral T-cell lymphoma, not otherwise characterized. Hepatosplenic gamma/delta T-cell lymphoma. Subcutaneous panniculitis-like T-cell lymphoma. Angioimmunoblastic T-cell lymphoma. Extranodal T-/NK-cell lymphoma, nasal type. Enteropathy-type intestinal T-cell (...) -cell, diffuse large cell, immunoblastic, and T-cell rich large B-cell lymphoma). Distinguish: Mediastinal large B-cell lymphoma. Follicular large cell lymphoma (grade 3). Anaplastic large cell lymphoma (CD30-positive). Extranodal NK-/T-cell lymphoma, nasal type/aggressive NK-cell leukemia/blastic NK-cell lymphoma. Lymphomatoid granulomatosis (angiocentric pulmonary B-cell lymphoma). Angioimmunoblastic T-cell lymphoma. Peripheral T-cell lymphoma, unspecified. Subcutaneous panniculitis-like T-cell

2018 PDQ - NCI's Comprehensive Cancer Database

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