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Panniculitis

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81. Lipofilling: A New Therapeutic Option for the Treatment of Lupus Panniculitis-Induced Atrophy (PubMed)

Lipofilling: A New Therapeutic Option for the Treatment of Lupus Panniculitis-Induced Atrophy Lupus panniculitis is a rare manifestation of cutaneous lupus erythematosus, which may lead to major aesthetic sequelae with a severe impact on patients' quality of life. We report 2 cases supporting the short- and long-term efficacy and safety of lipofilling in the treatment of lupus panniculitis-induced atrophy. These observations pave the way for prospective, larger-scale studies in patients (...) with scarring lupus panniculitis, provided that the autoimmune pathogenic process is in complete, stable remission.

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2016 Case reports in dermatology

82. Idiopathic pleural panniculitis with recurrent pleural effusion not associated with Weber-Christian disease (PubMed)

Idiopathic pleural panniculitis with recurrent pleural effusion not associated with Weber-Christian disease A 82-year-old patient with dyspnea and a recurrent history of pleural effusion was admitted into our unit. He performed a Chest computed tomography showing right pleural effusion. Video-assisted thoracoscopy (VATS) exploratory showed parietal pleural thickening of adipose tissue. The surgical procedure consisted, therefore, in the execution of multiple biopsies of the parietal pleura (...) which appeared covered, on the whole surface, by islands of adipose tissue, without macroscopic pathological aspects. After the procedure was performed pleurodesis with talc. The definitive histological examination consisted of normal mesothelial cells surrounded by fatty tissue infiltrated by small lymphocytes in a patient without skin lesions or visceral or systemic signs of inflammatory involvement of the adipose tissue. We reported a rare case of idiopathic pleural panniculitis with recurrent

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2016 Open Medicine

83. Purulent lupus panniculitis unmasked by FDG-PET/CT scan: A case report. (PubMed)

Purulent lupus panniculitis unmasked by FDG-PET/CT scan: A case report. Lupus panniculitis (LP) is a unique variant of cutaneous lupus erythematosus. Clinical manifestations are typically mild and include erythema, nodules, and small ulcers. In certain cases, diagnosing LP may be challenging. Skin overlying the typical subcutaneous inflammation may appear normal, and bacterial superinfections of the skin sometimes mask the underlying LP. It has been suggested that a computed tomography (CT

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2016 Medicine

84. Case report of subcutaneous panniculitis-like T-cell lymphoma complicated by eyelid swelling. (PubMed)

Case report of subcutaneous panniculitis-like T-cell lymphoma complicated by eyelid swelling. Subcutaneous panniculitis-like T-cell lymphoma (SPTCL) is a rare, highly malignant, extranodal lymphoma that preferentially infiltrates into subcutaneous adipose tissue. No case of SPTCL with the earliest symptoms occurring in the eye region has been reported. We report a case of SPTCL complicated by eyelid swelling.A 19-year-old Japanese man presented with worsening left eyelid swelling. The patient's (...) panniculitis, and inflammatory pseudotumor. Systemic antibiotics were initiated. The following day, he underwent a sub-Tenon's injection of triamcinolone. Left eyelid swelling gradually improved. He was discharged on the ninth day and followed up with oral prednisolone. Two months later, he visited our department because of a high fever and slight right eyelid swelling. Ocular hypertension was detected. A blood examination revealed pancytopenia. Computed tomography showed fluid retention, hydrothorax

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2016 BMC Ophthalmology

85. Cohort study of mesenteric panniculitis and its relationship to malignancy. (PubMed)

Cohort study of mesenteric panniculitis and its relationship to malignancy. Mesenteric panniculitis (MP) is a rare condition that historically has been associated with the presence of malignancy. Paraneoplastic phenomena in general regress with cure and in most cases with treatment of the cancer. This study was undertaken to determine whether MP regressed with cancer treatment and cure.This was a retrospective review of a database of all patients with MP confirmed on CT between 2003 and August

2016 British Journal of Surgery

86. Recurrent lipoatrophic panniculitis of children. (PubMed)

Recurrent lipoatrophic panniculitis of children. Recurrent panniculitis in children with lipoatrophy has been loosely described and reported under different names, but has never been systematically evaluated by immunohistochemical stains.To depict the profile of children with recurrent idiopathic panniculitis.Study of clinical, histopathological and immunohistochemical features in five cases with recurrent idiopathic panniculitis.Five children with repeated attacks of painful subcutaneous (...) nodules in association with fever, malaise and abdominal pain or arthralgia, with subsequent lipoatrophy were reviewed. In two patients, extensive involvement led to loss of the cutaneous fatty tissue. Laboratory abnormalities included increased acute phase reactants, leukocytosis with mild neutrophilia, microcytic anaemia and elevated liver enzymes. Histopathology showed lobar panniculitis without vasculitis and with a mixed infiltrate, composed of neutrophils, mononuclear cells, lymphocytes

2016 Journal of the European Academy of Dermatology and Venereology

87. Pancreatic panniculitis associated with pancreatic carcinoma: A case report. (PubMed)

Pancreatic panniculitis associated with pancreatic carcinoma: A case report. Pancreatic panniculitis is a very rare complication of pancreatic cancer, most often accompanying rare acinar cell carcinoma. We herein report a case of pancreatic panniculitis that was associated with pancreatic mucinous adenocarcinoma.A 57-year-old male was referred to our hospital for weight loss. A physical examination revealed subcutaneous nodules on his lower extremities. The blood test showed abnormal increases (...) in amylase, lipase, and carbohydrate antigen 19-9 levels. A computed tomography scan detected a hypodense 2 × 1.5 cm solid mass with an unclear margin in the head of the pancreas. The biopsy of subcutaneous nodules on the lower extremities was conducted and revealed lobular panniculitis. Pancreatic cancer and pancreatic panniculitis were strongly suspected. After the administration of octreotide acetate and the Whipple procedure, the serous amylase and lipase levels returned to normal, and the pancreatic

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2016 Medicine

88. Crohn's disease mistaken for long-standing idiopathic mesenteric panniculitis: A case report and management algorithm. (PubMed)

Crohn's disease mistaken for long-standing idiopathic mesenteric panniculitis: A case report and management algorithm. Mesenteric panniculitis (MP) is mostly an associated sign of an intra-abdominal or systemic inflammatory primary disease. Nevertheless, etiological and differential diagnosis of idiopathic MP can be challenging when an associate primary cause is not in the foreground.We report here the case of an isolated small bowel Crohn's disease, long time considered as idiopathic MP.This

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2016 Medicine

89. Subcutaneous Panniculitis-like T cell Lymphoma: Immunosuppressive Drugs Induce Better Response than Polychemotherapy. (PubMed)

Subcutaneous Panniculitis-like T cell Lymphoma: Immunosuppressive Drugs Induce Better Response than Polychemotherapy. Subcutaneous panniculitis-like T-cell lymphoma (SPTCL) is a rare condition usually considered to have a favourable prognosis. However, it is not known whether polychemotherapy or immunosuppressive-based therapy is the best approach for treating SPTCL. Using data collected between 2000 and 2012 in France, we analysed clinical, biological and pathological data of 27 patients (...) with SPTCL. Medical history revealed that 40% of patients had been previously diagnosed with an autoimmune disorder and 22% with inflammatory panniculitis. Haemophagocytic syndrome was present in 37% of cases. Autoantibodies were positive in 65% of cases. Complete remission (CR) was reached in 74% of cases. Immunosuppressive drug treatment was given in 69.5% of patients (group 1) and polychemotherapy in 30.5% (group 2). CR was 81.2% and 28.5% (p?=?0.025), respectively. Progression rate was 6.2% and 42.8

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2016 Acta Dermato-Venereologica

90. Mesenteric panniculitis: systematic review of cross-sectional imaging findings and risk of subsequent malignancy. (PubMed)

Mesenteric panniculitis: systematic review of cross-sectional imaging findings and risk of subsequent malignancy. Systematic review to determine any association between imaging features of idiopathic mesenteric panniculitis (MP) and subsequent malignancy.Two researchers searched primary literature independently for imaging studies of MP. They extracted data focusing on methodology for unbiased patient accrual and capability to determine a link between MP and subsequent malignancy. They noted (...) with certainty.• Our systematic review of mesenteric panniculitis found that imaging studies were biased. • Spectrum and recruitment bias was largely due to retrospective study designs. • No study could confirm a certain link between mesenteric panniculitis and subsequent malignancy. • Excessive methodological heterogeneity precluded meaningful meta-analysis. • High-quality research linking mesenteric panniculitis imaging features and subsequent malignancy is needed.

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2016 European radiology

91. Neutrophilic panniculitis and autoinflammation: what's the link? (PubMed)

Neutrophilic panniculitis and autoinflammation: what's the link? 27035799 2017 10 10 2018 12 02 1365-2133 175 3 2016 09 The British journal of dermatology Br. J. Dermatol. Neutrophilic panniculitis and autoinflammation: what's the link? 646-7 10.1111/bjd.14606 Marzano A V AV 0000-0002-8160-4169 Dipartimento di Fisiopatologia Medico-Chirurgica e dei Trapianti, Università degli Studi di Milano, Unità Operativa di Dermatologia, IRCCS Fondazione Ca' Granda, Ospedale Maggiore Policlinico, Milan (...) Panniculitis 2016 4 2 6 0 2016 4 2 6 0 2017 10 11 6 0 ppublish 27035799 10.1111/bjd.14606

2016 British Journal of Dermatology

92. Pancreatic panniculitis in a patient with pancreatic-type acinar cell carcinoma of the liver - case report and review of literature. (PubMed)

Pancreatic panniculitis in a patient with pancreatic-type acinar cell carcinoma of the liver - case report and review of literature. Pancreatic panniculitis is a rare condition, which has only been described in relation with pancreatic diseases up to now. It is characterized by necrotizing subcutaneous inflammation and is thought to be triggered by adipocyte necrosis due to systemic release of pancreatic enzymes with consecutive infiltration of neutrophils. We present the first case (...) of a patient with pancreatic panniculitis caused by pancreatic-type primary acinar cell carcinoma (ACC) of the liver and without underlying pancreatic disease.A 73-year old Caucasian female patient was referred to our department with painful cutaneous nodules persisting for eight weeks and with marked lipasemia (~15000 U/l; normal range <60 U/l). Four weeks prior, several liver lesions had been detected. Empiric treatment with steroids did not show any effect. A biopsy of the skin nodules revealed

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2016 BMC Cancer

93. Case report on a patient with lupus panniculitis (PubMed)

Case report on a patient with lupus panniculitis Lupus panniculitis is a rare variant of lupus erythematosus. It may occur as a separate disease or coexist with systemic or discoid lupus erythematosus. It is characterized by persistent, tender and hard nodules localised on the face, arms, shoulders, breast and buttocks. Healing of lesions is associated with scarring, lipoatrophy and rarely ulceration. Treatment of lupus panniculitis depends on disease advancement or concomitance of additional (...) lupus erythematosus symptoms. We report a case of a 44-year-old patient with lupus panniculitis treated with chloroquine and glucocorticosteroids, including high dose infusions. Despite intense treatment, the patient developed symptoms that suggested a diagnosis of systemic lupus erythematosus.

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2015 Advances in Dermatology and Allergology/Postȩpy Dermatologii i Alergologii

94. Lupus Panniculitis as an Initial Manifestation of Systemic Lupus Erythematosus: A Case Report. (PubMed)

Lupus Panniculitis as an Initial Manifestation of Systemic Lupus Erythematosus: A Case Report. Lupus erythematosus panniculitis (LEP) is a variant of chronic cutaneous lupus erythematosus (CCLE). Reported cases of LEP lesions before the diagnosis of systemic lupus erythematosus (SLE) were very rare; only 9 cases have been reported, to the best of our knowledge. We now describe the case of a 19-year-old male patient, with an overall review of the English literature. In the earliest stage

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2016 Medicine

95. Mesenteric Panniculitis: An Unusual Cause of Epigastric Pain (PubMed)

Mesenteric Panniculitis: An Unusual Cause of Epigastric Pain 26816946 2016 01 28 2018 11 13 2249-782X 9 12 2015 Dec Journal of clinical and diagnostic research : JCDR J Clin Diagn Res Mesenteric Panniculitis: An Unusual Cause of Epigastric Pain. PJ01 10.7860/JCDR/2015/15533.6882 Jerraya Hichem H Faculty of Medicine, Department "B" of General Surgery, Charles Nicolle Hospital , Boulevard du 9 Avril, 1006 Tunis, Tunisia . Khalfallah Mehdi M Faculty of Medicine, Department "B" of General Surgery

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2015 Journal of clinical and diagnostic research : JCDR

96. A case report of an 80 year old man with mesenteric panniculitis, a raised lactate and hyperglycaemia (PubMed)

A case report of an 80 year old man with mesenteric panniculitis, a raised lactate and hyperglycaemia Mesenteric panniculitis is a rare condition which presents as abdominal pain. It involves benign inflammatory or fibrotic changes affecting the mesentery of the bowel.An 80 year old man presented with severe abdominal pain of acute onset. He was found to have a high lactate and high blood glucose. He was not a known diabetic. A computed tomography (CT) scan revealed a diagnosis of mesenteric (...) panniculitis, and the patient rapidly responded to steroid treatment.Mesenteric panniculitis has been known to present as an acute abdomen. However, an associated high lactate and hyperglycaemia is hitherto unreported in the literature. With no obvious precipitant for an increased lactate, we propose it is potentially caused by the subsequent fat necrosis and regional ischaemia associated with mesenteric panniculitis.This case report underlines the importance of further research into the relationship

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2015 International journal of surgery case reports

97. Lymphocytic panniculitis: an algorithmic approach to lymphocytes in subcutaneous tissue. (PubMed)

Lymphocytic panniculitis: an algorithmic approach to lymphocytes in subcutaneous tissue. The diagnosis of panniculitis is a relatively rare occurrence for many practising pathologists. The smaller subset of lymphocyte-predominant panniculitis is further complicated by the diagnostic consideration of T cell lymphoma involving the subcutaneous tissue, mimicking inflammatory causes of panniculitis. Accurate classification of the panniculitis is crucial to direct clinical management as treatment (...) -predominant panniculitis, including entities of septal-predominant pattern panniculitis (erythema nodosum, deep necrobiosis lipoidica, morphea profunda and sclerosing panniculitis) and lobular-predominant pattern panniculitis (lupus erythematous panniculitis/lupus profundus, subcutaneous panniculitis-like T cell lymphoma, cutaneous γ-δ T cell lymphoma, Borrelia infection and cold panniculitis). Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence

2015 Journal of Clinical Pathology

98. Neutrophilic Panniculitis Associated with Alpha-1 Antitrypsin Deficiency: an Update. (PubMed)

Neutrophilic Panniculitis Associated with Alpha-1 Antitrypsin Deficiency: an Update. Neutrophilic panniculitis associated with alpha-1-antitrypsin deficiency (AATD) is a very rare disease. Its estimated prevalence is 1 in 1000 subjects with severe AATD (usually white individuals with a Pi*ZZ genotype). It is manifested clinically by painful recurrent ulcerating subcutaneous nodules, and characterized histologically by dense infiltrates of neutrophils in the deep dermis and connective-tissue (...) septae, with secondary lobular panniculitis. It may be the only clinical manifestation of AATD, although it can also occur together with the classical pulmonary or hepatic manifestations of the disease. AATD-associated panniculitis is not only very rare but may also be significantly underdiagnosed. The physician managing a case of panniculitis with a clinical presentation suggestive of AATD and a compatible skin biopsy should measure serum AAT concentration and, if low, determine the AAT phenotype

2015 British Journal of Dermatology

99. Non-infectious Panniculitis During Hydroxyurea Therapy in a Patient with Myeloproliferative Disease. (PubMed)

Non-infectious Panniculitis During Hydroxyurea Therapy in a Patient with Myeloproliferative Disease. 26576655 2017 01 17 2017 01 17 1651-2057 96 4 2016 May Acta dermato-venereologica Acta Derm. Venereol. Non-infectious Panniculitis during Hydroxyurea Therapy in a Patient with Myeloproliferative Disease. 566-7 10.2340/00015555-2292 Ogawa Yasushi Y Department of Dermatology, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya 466-8550, Japan. Akiyama Masashi M eng (...) Panniculitis chemically induced diagnosis drug therapy Remission Induction Treatment Outcome 2015 11 19 6 0 2015 11 19 6 0 2017 1 18 6 0 ppublish 26576655 10.2340/00015555-2292

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2015 Acta Dermato-Venereologica

100. Lobular Panniculitic Infiltrates With Overlapping Histopathologic Features of Lupus Panniculitis (Lupus Profundus) and Subcutaneous T-cell Lymphoma: A Conceptual and Practical Dilemma. (PubMed)

Lobular Panniculitic Infiltrates With Overlapping Histopathologic Features of Lupus Panniculitis (Lupus Profundus) and Subcutaneous T-cell Lymphoma: A Conceptual and Practical Dilemma. Subcutaneous panniculitis-like T-cell lymphoma (SPTCL) is characterized by panniculitic infiltrates that may be difficult to distinguish from inflammatory disorders, particularly lupus erythematosus profundus (LEP). We report on 11 patients (M:F=5:6; median age: 49 y; range: 20 to 75 y) presenting with lobular

2014 American Journal of Surgical Pathology

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