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641. Mycosis Fungoides and Cutaneous T-cell Lymphomas

for Research and Treatment of Cancer (EORTC) [ ] : Indolent clinical behaviour Mycosis fungoides. Variants and subtypes of mycosis fungoides. Folliculotropic mycosis fungoides. Pagetoid reticulosis. Granulomatous slack skin. Primary cutaneous anaplastic large cell lymphoma (CD30+). Lymphomatoid papulosis (CD30+). Subcutaneous panniculitis-like T-cell lymphoma. Primary cutaneous CD4+ small or medium pleomorphic T-cell lymphoma. Aggressive clinical behaviour Sézary's syndrome. Primary cutaneous natural (...) and infection as the skin turns into ulcerating, necrotic tumours. Differential diagnosis Early in the course of disease, skin lesions may be nonspecific, with a non-diagnostic biopsy result; hence, confusion with benign conditions is common. The most important differential diagnoses of the CTCLs include: [ ] All kinds of dermatitis and eczema. Adverse drug reactions. Parapsoriasis. Psoriasis. Lichen planus. Morphea. Panniculitis. Folliculitis. Pityriasis lichenoides chronica. Pityriasis lichenoides et

2008 Mentor

642. Autoimmune Hepatitis

a poorer prognosis than those without. Associated diseases Concurrent autoimmune disorders occur in approximately 40% of patients, particularly autoimmune thyroid disorder. [ ] Haematological: , , , , . Gastrointestinal: , . . Fibrosing alveolitis. and . Endocrine: , autoimmune thyroiditis, . Rheumatological: and , , , , leukocytoclastic vasculitis, febrile panniculitis. . . . Management [ ] Patients with moderate or severe inflammation (defined as one or more of serum AST >5 times normal, serum

2008 Mentor

643. Acute Pancreatitis

Gastrointestinal: Haemorrhage Ileus Weber-Christian disease: Subcutaneous fat necrosis - relapsing febrile nodular nonsuppurative panniculitis. Recurring crops of tender nodules in the skin and subcutaneous fat of the trunk, thighs and buttocks, which is more common in middle-aged women. These often ulcerate and then scar on healing. Difficult to treat - try prednisolone or immunosuppressives. Splenic vein thrombosis. Prognosis 80% of patients have mild disease and recover without complications

2008 Mentor

644. Acute Appendicitis

value (NPV) of 53% for appendicitis. [ ] Differential diagnosis Other causes of abdominal pain Gastrointestinal , , , , , , mesenteric adenitis, , , , , rectus sheath haematoma, . Urological , , . Gynaecological , torsion or rupture of an , . Others , , , adverse effects from immune modulation therapies (eg, panniculitis in the abdomen at the left iliac fossa, associated with beta-interferon injection). [ ] Other causes of RIF mass These include: Crohn's disease, carcinoma of colon, mucocele (...) adult. Ann Afr Med. 2009 Apr-Jun8(2):133-5. doi: 10.4103/1596-3519.56243. ; Diagnosis and Treatment of Caecal Volvulus, Postgrad Med J 200581:772-776. ; The use of the clinical scoring system by Alvarado in the decision to perform Am J Emerg Med. 2007 Jun25(5):489-93. ; Development of the RIPASA score: a new appendicitis scoring system for the diagnosis of acute appendicitis. Singapore Med J. 2010 Mar51(3):220-5. ; Interferon beta-induced panniculitis mimicking acute appendicitis. Arch Dermatol

2008 Mentor

645. Cutaneous lymphomas with prominent granulomatous reaction: a potential pitfall in the histopathologic diagnosis of cutaneous T- and B-cell lymphomas. (Abstract)

cutaneous T-cell lymphomas and B-cell lymphomas (primary cutaneous lymphoma 22, secondary cutaneous lymphoma one). Biopsies of 23 patients with histopathologic features of cutaneous T-cell lymphoma or cutaneous B-cell lymphoma with prominent granulomatous reaction were included in this study. A prominent granulomatous reaction was defined as the presence of a granulomatous component exceeding 25% of the dermal infiltrate. There were 14 cases of mycosis fungoides, two of subcutaneous panniculitis-like T

2002 American Journal of Surgical Pathology

646. Cytotoxic/natural killer cell cutaneous lymphomas. Report of EORTC Cutaneous Lymphoma Task Force Workshop. (Abstract)

collected for a workshop of the European Organization for Research and Treatment of Cancer Cutaneous Lymphoma Task Force, to better clarify the clinical, morphologic, and phenotypic features of these uncommon tumors.Several categories with different clinical and pathologic features were delineated: 1) aggressive, CD8+, epidermotropic, cytotoxic T-cell lymphoma; 2) mycosis fungoides, cytotoxic immunophenotype variant; 3) subcutaneous panniculitis-like T-cell lymphoma; 4) NK/T-cell lymphoma, nasal type; 5

2003 Cancer

647. Characteristics of cutaneous lymphomas in Korea. (Abstract)

a recent 3-year period. The clinical records, haematoxylin & eosin-stained slides and immunohistochemical stains from 80 patients with malignant lymphomas of the skin were reviewed. In our study, the most frequent cutaneous lymphoma was mycosis fungoides. Compared with Western countries, Korea had higher rates of NK/T cell lymphoma and subcutaneous panniculitis-like T-cell lymphoma and a much lower rate of B-cell lymphoma. The occurrence rates for various subtypes of malignant lymphoma in Korea

2003 Clinical & Experimental Dermatology

648. Cutaneous lymphomas other than mycosis fungoides in Singapore: a clinicopathological analysis using recent classification systems. (Abstract)

. The immunohistological diagnosis was correlated with the clinical presentation and staging investigations for the final diagnosis and the course of disease recorded.Non-MF T-cell lymphomas presenting in the skin comprised 31 cases (78%) and were 3(1/2) times more common than B-cell lymphomas, which comprised nine cases (22%). The common subtypes were lymphomatoid papulosis, CD30+ large cell cutaneous T-cell lymphoma and subcutaneous panniculitis-like T-cell lymphoma. The commonly ascribed B-cell pattern (...) with infiltrates in the mid and deep dermis and perivascular spaces was seen in 60% of T-cell lymphomas. Overall, there were equal numbers of primary cutaneous T-cell lymphomas and those due to concurrent or secondary cutaneous lymphoma. Five of six cases of subcutaneous panniculitis-like T-cell lymphoma had concurrent cutaneous and systemic involvement and their median survival was 7 months.The predominance of cutaneous T-cell lymphomas in this case series closely matched that reported from east Asia

2003 British Journal of Dermatology

649. The spectrum of cutaneous disease in multiple myeloma. (Abstract)

of lymphocyte recovery (3), thrombocytopenia-related lesions (9), normolipemic plane xanthoma (1), amyloidosis (1), Sweet's syndrome (7), panniculitis (1), papulosquamous lesions (18), bullous diseases (17), vasculitis (11), infectious lesions (41), granulomatous dermatitis (6), alopecia cicatrisata (1), nonspecific lesions (77), and unrelated lesions (2).Skin biopsy specimens from patients with MM less than 60 days from transplant most commonly show sequelae of the transplant such as graft-versus-host

2003 Journal of American Academy of Dermatology

650. Sporotrichoid cutaneous Mycobacterium avium complex infection. (Abstract)

ulcers, inflammatory nodules, panniculitis, pustular lesions, and draining sinuses. Localized skin involvement resembling sporotrichosis is unusual and to our knowledge has been reported only once in the English-language literature. We describe an additional case of primary cutaneous M avium complex infection manifesting as sporotrichosis-like lesions on a patient with AIDS.

2002 Journal of American Academy of Dermatology

651. Branched filaments no fungus, ovoid bodies no bacteria: Two unusual cases of mycetoma. (Abstract)

Branched filaments no fungus, ovoid bodies no bacteria: Two unusual cases of mycetoma. We describe a 58-year-old man presenting with necrotizing panniculitis of the lower right leg and a 64-year-old woman with a clinically similar lesion combined with pustular eruptions and subsequent ulceration on the forehead. In the first patient, Giemsa staining showed small ovoid bodies and Grocott staining revealed hyphae. Histology from the process on the forehead showed branched filaments

2003 Journal of American Academy of Dermatology

652. Facial lupus erythematosus profundus in a 9-year-old boy. Full Text available with Trip Pro

Facial lupus erythematosus profundus in a 9-year-old boy. 9659310 1998 07 17 2018 11 13 0141-0768 91 4 1998 Apr Journal of the Royal Society of Medicine J R Soc Med Facial lupus erythematosus profundus in a 9-year-old boy. 207-8 Muncaster A A Selly Oak Hospital, Birmingham, UK. Stewart G G Moss C C Southwood T T eng Case Reports Journal Article England J R Soc Med 7802879 0141-0768 IM Child Facial Dermatoses diagnosis Humans Lymphatic Diseases etiology Male Panniculitis, Lupus Erythematosus

1998 Journal of the Royal Society of Medicine

653. Primary Cutaneous CD8-Positive Epidermotropic Cytotoxic T Cell Lymphomas : A Distinct Clinicopathological Entity with an Aggressive Clinical Behavior Full Text available with Trip Pro

of the 17 cases expressed markers characteristic of natural killer cells or gamma/delta T cells. Nine of 17 cases showed the characteristic clinical and histological features as well as clinical behavior of well defined types of CTCL, such as mycosis fungoides (2 cases), pagetoid reticulosis (2 cases), lymphomatoid papulosis (2 cases), and CD30+ large T cell lymphoma (2 cases), all of which usually express a CD4+ T cell phenotype, and 1 case of subcutaneous panniculitis-like T cell lymphoma. The other 8

1999 The American journal of pathology

654. Defect of a complement receptor 3 epitope in a patient with systemic lupus erythematosus. Full Text available with Trip Pro

Defect of a complement receptor 3 epitope in a patient with systemic lupus erythematosus. Complement receptor 3 (CR3) is expressed on cells of the reticuloendothelial system and involved in the clearance of immune complexes. In this article a patient with a deficiency of the C3bi binding site of this receptor is described. Clinically this patient exhibited predominantly cutaneous manifestations of a systemic lupus erythematosus with an immune vasculitis and panniculitis. The deficiency

1993 Journal of Clinical Investigation

655. Out of Africa: observations on the histopathology of Mycobacterium ulcerans infection. Full Text available with Trip Pro

Panniculitis microbiology pathology Skin pathology Skin Diseases, Bacterial microbiology pathology Skin Ulcer microbiology pathology 20 1993 1 1 1993 1 1 0 1 1993 1 1 0 0 ppublish 8432888 PMC501092 Trop Geogr Med. 1959 Dec;11:293-312 14406764 Int J Lepr. 1965 Jul-Sep;33(3):Suppl:698-709 5322711 Int J Lepr Other Mycobact Dis. 1966 Jul-Sep;34(3):255-73 5950347 Med J Aust. 1967 Mar 4;1(9):427-31 5336860 Australas J Dermatol. 1985 Aug;26(2):67-73 4084161 East Afr Med J. 1963 Apr;40:113-7 13931729 J Trop Med

1993 Journal of Clinical Pathology

656. Depsipeptide to Treat Patients With Cutaneous T-Cell Lymphoma and Peripheral T-Cell Lymphoma

will be enrolled in a fourth arm. These include but are not exclusively limited to: Enteropathy-type T cell lymphoma; Hepatosplenic T-cell lymphoma; Subcutaneous panniculitis-like T cell lymphoma; Angioimmunoblastic T-cell lymphoma; Anaplastic large cell lymphoma. Patients must have experienced disease progression after receiving prior standard treatment. There will be no limit on the number of prior regimens. Primitive T cell neoplasms and T cell leukemias will not be enrolled. Patients with peripheral T-cell

2000 Clinical Trials

657. Combination Chemotherapy With or Without Rituximab in Treating Older Patients With Non-Hodgkin's Lymphoma

marginal zone lymphoma (monocytoid) T-cell NHL including the following: Lymphoblastic precursor T-cell lymphoma Peripheral T-cell lymphoma (PTCL) not otherwise specified (NOS) Lennert's lymphoma T-zone lymphoma T-cell lymphoma of the angioimmunoblastic lymphadenopathy with dysproteinemia (AILD) type Anaplastic large cell lymphoma ALK^+ ALK^- Extranodal NK/T-cell lymphoma, nasal type Intestinal T/NK-cell lymphoma (with or without enteropathy) Hepatosplenic gamma-delta lymphoma Subcutaneous panniculitis

2003 Clinical Trials

658. Campath-1H and EPOCH to Treat Non-Hodgkin's T- and NK-Cell Lymphomas

(not otherwise specified (nos)), gamma-delta hepatosplenic T cell lymphoma, subcutaneous panniculitis-like T cell, NK-T cell lymphoma confirmed by pathology or flow cytometry staff of the Hematopathology Section, Laboratory of Pathology, NCI. Patients with alk-positive anaplastic large cell lymphoma and patients with T cell precursor disease are not eligible. Age greater than or equal to 17 years. Laboratory tests: Creatinine less than or equal to 1.5 mg/dL or creatinine clearance greater than or equal to 60

2003 Clinical Trials

659. panniculitis

panniculitis panniculitis - General Practice Notebook This site is intended for healthcare professionals General Practice Notebook | Medical search panniculitis Erythema nodosum is a panniculitis - an inflammation of the fat, seen principally in adult females. The female to male ratio is five to one but in children the ratio is 1:1 The disease can be seen at any age with a peak incidence between the ages of 20 and 30 years (1). The manifestation is with red nodules - in the literal translation

2010 GP Notebook

660. alpha1-Antitrypsin deficiency presenting with panniculitis and incidental discovery of chronic obstructive pulmonary disease. (Abstract)

alpha1-Antitrypsin deficiency presenting with panniculitis and incidental discovery of chronic obstructive pulmonary disease. A 60-year-old man presented to the Emergency Department (ED) with large, painful, indurated plaques on the right thigh, left abdomen, left chest, and right chest, which began without any preceding trauma on the right thigh 3 weeks prior to presentation in the ED. He was initially treated with cefazolin 1 g three times daily as home infusions. When the lesions continued (...) , draining an oily liquid (Figs 1 and 2). An incisional biopsy was obtained from his thigh. Histopathology showed a septal and lobular panniculitis with fat necrosis, neutrophils, and histiocytes (Fig. 3). Special stains for organisms were negative. Tissue sent for bacterial and fungal culture had no growth. Amylase and lipase levels were normal. Rheumatoid factor, antinuclear antibody (ANA), antineutrophil cytoplasmic antibody (ANCA), cryoglobulins, and antiphospholipid antibodies were all normal

2007 International Journal of Dermatology

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