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541. Clinical Evaluation of the SNaP Wound Care System in Promoting Healing in Chronic Wounds

a thick eschar that persists after wound debridement. Patient has an HbA1C >12%. Patient has ulcers due to inflammatory conditions such as pyoderma gangrenosum, rheumatoid arthritis, vasculitis, cryoglobulinaemia, necrobiosis lipoidica, panniculitis, lupus erythematosus, scleroderma, or calcinosis. Patient has untreated osteomyelitis. Patient has any other condition that, in the opinion of the investigator, makes the patient inappropriate to take part in this study. Patient is allergic to the wound

2011 Clinical Trials

542. Vitamin D Status, Disease Specific and Quality of Life Outcomes in Patients With Cutaneous Lupus

and Severity Index) is a validated CLE disease severity measure that has been in use in clinical trials since 2005. This scale captures cutaneous, mucosal membrane, and alopetic disease activity (erythema and scale/hypertrophy) as well as damage (dyspigmentation and scarring/ atrophy/ panniculitis). Secondary Outcome Measures : Quality of life as measured by the Skindex 29 [ Time Frame: 1 year ] No cutaneous lupus specific quality of life (QOL) measure exists, but the Skindex 29, a validated skin-specific

2011 Clinical Trials

543. A Japanese Phase 1/2 Study to Assess the Efficacy, Safety and Pharmacokinetics of Romidepsin in Patients With Peripheral T-cell Lymphoma (PTCL)

for study participation and have: Histologically confirmed Peripheral T cell Lymphoma (PTCL) Not Otherwise Specified (NOS), Angioimmunoblastic T-cell Lymphoma, enteropathy- type T-cell lymphoma, subcutaneous panniculitis-like T-cell lymphoma, cutaneous T-cell lymphoma (excludes mycosis fungoides or Sezary syndrome) , hepatosplenic T-cell lymphoma, Anaplastic Large cell lymphoma (ALCL) [anaplastic lymphoma kinase-1 (ALK-1) negative], patients with ALK 1 expressing ALCL (ALK-1 positive) who have relapsed

2011 Clinical Trials

544. Clinical Usefulness and Prognostic Significance of Interim 18F-FDG PET/CT for the Treatment of Peripheral T Cell Lymphomas

, first analysis of clinical data will be performed at the time of 80 patients enrolled or after a median follow-up of more than 12 months. Criteria Inclusion Criteria: Age above 18 years Histologically proven PTCLs except primary cutaneous/subcutaneous panniculitis ECOG performance status ≤ 2 Patients who are available to be performed PET/CT at diagnosis No severe concomitant disease Exclusion Criteria: Patients who did not undergo PET/CT scans at diagnosis Patients who have a primary CNS lymphoma

2011 Clinical Trials

545. Study of Pralatrexate Versus Observation Following CHOP-based Chemotherapy in Previously Undiagnosed Peripheral T-cell Lymphoma Patients

T-cell leukemia virus 1+) Angioimmunoblastic TCL Anaplastic large cell lymphoma (ALCL), primary systemic type, excluding anaplastic lymphoma kinase positive (ALK+) with International Prognostic Index (IPI) score less than 2 at initial diagnosis and complete response (CR) after CHOP-based therapy PTCL-unspecified Enteropathy-type intestinal lymphoma Hepatosplenic TCL Subcutaneous panniculitis TCL Transformed mycosis fungoides (tMF) Extranodal T/NK-cell lymphoma nasal or nasal type Primary

2011 Clinical Trials

546. Phase 1 Trial of Siplizumab and Dose-Adjusted EPOCH-Rituximab in T- and NK-Cell Lymphomas

the fourth and sixth treatment cycles (approximately weeks 12 and 18) of siplizumab-EPOCH-R, study researchers will perform blood tests and CT/MRI scans on all patients to assess their response to the treatment. Condition or disease Intervention/treatment Phase T-Cell Peripheral Lymphoma Gamma Delta Hepatosplenic T-Cell Lymphoma Subcutaneous Panniculitis-Like T-Cell Lymphoma NK T-Cell Lymphoma Biological: Rituximab Drug: EPOCH Biological: Siplizumab Phase 1 Detailed Description: Background: The clinical (...) (nos), gamma-delta hepatosplenic T cell lymphoma, subcutaneous panniculitis-like T cell, NK-T cell lymphoma confirmed by pathology or flow cytometry staff of the Hematopathology Section, Laboratory of Pathology, NCI. Patients with alk-positive anaplastic large cell lymphoma and patients with T cell precursor disease are not eligible. Age greater than or equal to 18 years. Laboratory tests: Creatinine less than or equal to 1.5 mg/dL or creatinine clearance greater than or equal to 60 ml/min

2011 Clinical Trials

547. Alisertib in Treating Patients With Relapsed or Refractory Peripheral T-Cell Non-Hodgkin Lymphoma

or negative Angioimmunoblastic T-cell NHL Subcutaneous panniculitis-like T-cell lymphoma Enteropathy-associated T-cell NHL Hepatosplenic T-cell lymphomas Extranodal natural killer (NK)/T-cell lymphoma, nasal type Adult T-cell leukemia/lymphoma Unclassifiable PTCL Transformed cutaneous T-cell lymphoma (CTCL) to PTCL with systemic involvement (not local skin transformation) No other histologies are eligible; examples of ineligible histologies include: T-cell prolymphocytic leukemia, T-cell large granular

2011 Clinical Trials

548. List of cutaneous conditions

, pressure-induced alopecia) (barber's itch, folliculitis barbae traumatica, razor bumps, scarring pseudofolliculitis of the beard, shave bumps) (alopecia cicatrisata) (pterygium inversus unguis, ventral pterygium) (dorsal pterygium) (brachyonychia, nail en raquette , racquet thumb) (idiopathic palmoplantar hidradenitis, idiopathic plantar hidradenitis, painful plantar erythema, palmoplantar eccrine hidradenitis, plantar panniculitis) (temporal alopecia, temporal triangular alopecia) (bamboo hair (...) ) (sandpapered nails, trachyonychia) ( cheveux incoiffable , pili trianguli et canaliculi, spun-glass hair) (woolly hair nevus) Conditions of the subcutaneous fat [ ] See also: Conditions of the are those affecting the layer of that lies between the and underlying . (Lawrence syndrome, Lawrence–Seip syndrome) (Dercum's disease) (alpha1-protease deficiency panniculitis, alpha1-proteinase deficiency panniculitis) (acquired partial lipodystrophy, cephalothoracic lipodystrophy, progressive lipodystrophy) (benign

2012 Wikipedia

549. Alpha 1-antitrypsin deficiency

patients. Patients are usually labeled as having COPD without an underlying cause. It is estimated that about 1% of all COPD patients actually have an A1AT deficiency. Thus, testing should be performed for all patients with COPD, asthma with irreversible airflow obstruction, unexplained , or necrotizing panniculitis. [ ] The initial test performed is serum A1AT level. A low level of A1AT confirms the diagnosis and further assessment with A1AT protein phenotyping and A1AT genotyping should be carried

2012 Wikipedia

550. Cutaneous sclerosis: a previously undescribed manifestation of sclerosing mesenteritis. Full Text available with Trip Pro

Cutaneous sclerosis: a previously undescribed manifestation of sclerosing mesenteritis. Sclerosing mesenteritis is a rare disease of unknown etiology that is characterized by self-limited, nonspecific inflammation and fibrosis of the mesenteric adipose tissue. Histologic classification characterizes 3 main stages in the evolution of the fibroinflammatory process: mesenteric lipodystrophy (ML), mesenteric panniculitis (MP), and sclerosing (retractile) mesenteritis (SM).A 68-year-old woman

2010 Archives of Dermatology

551. Subcutaneous fat necrosis as a complication of whole-body cooling for birth asphyxia. Full Text available with Trip Pro

Subcutaneous fat necrosis as a complication of whole-body cooling for birth asphyxia. Subcutaneous fat necrosis (SCFN) of the newborn is a form of panniculitis that affects full-term neonates who often have suffered either birth asphyxia or hypothermia. The induction of hypothermia in newborns is becoming frequently used to reduce the neurologic sequelae associated with birth asphyxia. The risk of SCFN in neonates undergoing this therapy is unknown. Observation We describe a neonate who

2010 Archives of Dermatology

552. Lupus Mastitis: An Uncommon Complication of Systemic or Discoid Lupus. (Abstract)

Lupus Mastitis: An Uncommon Complication of Systemic or Discoid Lupus. Lupus mastitis is an uncommon presentation of lupus erythematosus profundus or lupus panniculitis, a rare variant of lupus erythematosus characterized by inflammation of the subcutaneous fat. Lupus mastitis can present as single or multiple subcutaneous or deep breast masses, often clinically mimicking malignancy. Although lupus mastitis is rare, with less than 25 cases reported, the histologic features are distinct (...) . Awareness of the entity and familiarity with the histologic features allow for accurate diagnosis and appropriate patient management. It most commonly affects women with a mean age at diagnosis of 40 years and an age range of 18 to 70 years. Typical histologic findings in lupus mastitis include a lymphocytic lobular panniculitis with plasma cells and hyaline fat necrosis. The lymphocytic infiltrate can be nodular, diffuse, periductal, and/or perilobular and germinal centers can frequently be identified

2010 American Journal of Surgical Pathology

553. Acute Fatal Fat Tissue Embolism After Autologous Fat Transfer in a Patient with Lupus Profundus. (Abstract)

, St Thomas' Hospital, Westminster Bridge Road, London SE1 7EH, United Kingdom. Lucas Sebastian S Langrish Christopher J CJ Barlow Richard J RJ eng Case Reports Journal Article 2010 11 17 United States Dermatol Surg 9504371 1076-0512 IM Acute Disease Adipose Tissue transplantation Adult Cosmetic Techniques adverse effects Embolism, Fat etiology Face Fatal Outcome Female Humans Panniculitis, Lupus Erythematosus pathology surgery Transplantation, Autologous 2010 11 25 6 0 2010 11 26 6 0 2011 2 18 6 0

2010 Dermatologic Surgery

554. Neutrophilic dermatoses in a patient with collagenous colitis Full Text available with Trip Pro

Neutrophilic dermatoses in a patient with collagenous colitis We report the case of a 75-year old woman with collagenous colitis who presented with erythematous and edematous plaques on the periorbital and eyelid regions, accompanied by oral ulcers. Histopathology showed a dermal neutrophilic infiltrate plus mild septal and lobular panniculitis with lymphocytes, neutrophils and eosinophils. Five years earlier she had presented a flare of papules and vesicles on the trunk, together with oral (...) ulcers; a skin biopsy revealed a neutrophilic dermal infiltrate and Sweet's syndrome was diagnosed. Both the neutrophilic panniculitis and the Sweet's syndrome were accompanied by fever, malaise and diarrhea. Cutaneous and intestinal symptoms disappeared with corticoid therapy. The two types of neutrophilic dermatoses that appeared in periods of colitis activity suggest that intestinal and cutaneous manifestations may be related.

2010 Dermatology Reports

555. The Differential Imaging Features of Fat-Containing Tumors in the Peritoneal Cavity and Retroperitoneum: the Radiologic-Pathologic Correlation Full Text available with Trip Pro

, until the lesions become large or symptomatic. The third group tumors (i.e., mesenteric panniculitis and pseudolipoma of Glisson's capsule) require medical treatment or no treatment at all. Identifying factors such as whether the fat is macroscopic or microscopic within the lesion, the origin of the lesions, and the presence of combined calcification is important for narrowing the differential diagnosis. The development and wide-spread use of modern imaging modalities make identification

2010 Korean Journal of Radiology

556. Clinical Pearls in Dermatology Full Text available with Trip Pro

Labialis diagnosis Humans Male Middle Aged Panniculitis diagnosis Pyoderma Gangrenosum diagnosis Scabies diagnosis Skin Diseases diagnosis therapy 2010 9 3 6 0 2010 9 3 6 0 2010 9 29 6 0 ppublish 20810795 S0025-6196(11)60215-2 10.4065/mcp.2010.0305 PMC2931620 Arch Dermatol. 2000 Mar;136(3):330-6 10724194 J Am Acad Dermatol. 2002 Feb;46(2):187-92 11807428 Mayo Clin Proc. 2003 Feb;78(2):174-94 12583529 Curr Opin Infect Dis. 2010 Apr;23(2):111-8 20075729 Int J Dermatol. 2004 Nov;43(11):790-800 15533059 J

2010 Mayo Clinic Proceedings

557. Inflammation and Oxidative Stress of Adipose Tissue in Sleep Apnea Syndrome

Posted: June 16, 2016 Last Verified: June 2016 Keywords provided by University Hospital, Grenoble: adipose tissue obese patients inflammation oxidative stress sleep apnea syndrome Additional relevant MeSH terms: Layout table for MeSH terms Syndrome Inflammation Apnea Sleep Apnea Syndromes Panniculitis Steatitis Disease Pathologic Processes Respiration Disorders Respiratory Tract Diseases Signs and Symptoms, Respiratory Signs and Symptoms Sleep Disorders, Intrinsic Dyssomnias Sleep Wake Disorders

2010 Clinical Trials

558. T-Cell Project: Prospective Collection of Data in Patients With Peripheral T-Cell Lymphoma

and biological information. Study Design Go to Layout table for study information Study Type : Observational Estimated Enrollment : 2000 participants Observational Model: Cohort Time Perspective: Prospective Official Title: Prospective Collection of Data in Pts With Peripheral T-Cell Lymphoma: PTCL,NOS;AITL; Extranodal NK/T-cell;Enteropathy-type; Hepatosplenic γ-δ; Subcutaneous Panniculitis-like; ALCL,Primary Systemic Type. By the Intl. T-Cell Lymphoma Project Study Start Date : September 2006 Estimated (...) lymphoma; Hepatosplenic T-cell lymphoma; Peripheral gamma-delta T-cell lymphoma; Subcutaneous panniculitis-like T-cell lymphoma; Unclassifiable peripheral T-cell Lymphoma Unclassifiable NK-cell lymphoma Age over 18 Tissue biopsies adequate for diagnosis and classification and available for centralized review Clinical data including baseline information on disease localization and laboratory parameters at staging, features of treatment adopted and assurance of follow-up updating for at least 5 years

2010 Clinical Trials

559. Comprehensive Oncology Measures for Peripheral T-cell Lymphoma Treatment Registry

with Peripheral T-cell Lymphoma (PTCL): Aggressive natural killer (NK)-cell leukemia Adult T-cell lymphoma/leukemia (human T-cell leukemia virus [HTLV] 1+) Angioimmunoblastic T-cell lymphoma Anaplastic large cell lymphoma (ALCL), primary systemic type (ALK+, ALK-) PTCL, not otherwise specified (NOS) T/NK-cell lymphoma, nasal type Enteropathy-type intestinal lymphoma Hepatosplenic T-cell lymphoma Subcutaneous panniculitis T-cell lymphoma Transformed mycosis fungoides (at diagnosis of transformation) T-cell

2010 Clinical Trials

560. Clinical Evaluation of the SNaP Wound Care System

-related cellulitis Patients with thick eschar at wound base post debridement Patients with wounds located in an area not amenable to forming an air- tight seal Ulcers due to inflammatory conditions such as pyodermagangrenosum, rheumatoid arthritis, vasculitis, cryoglobulinemia, necrobiosislipoidicadiabeticorum, lupus or pancreatic panniculitis, cryofibrinogenemia, calcinosis cutis, scleroderma, Raynaud's syndrome Patient has untreated osteomyelitis Patient is allergic to wound care products Patient

2010 Clinical Trials

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