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2. The coexistence of lupus erythematosus panniculitis and subcutaneous panniculitis-like T-cell lymphoma in the same patient (PubMed)

The coexistence of lupus erythematosus panniculitis and subcutaneous panniculitis-like T-cell lymphoma in the same patient 29892661 2019 02 26 2352-5126 4 2 2018 Mar JAAD case reports JAAD Case Rep The coexistence of lupus erythematosus panniculitis and subcutaneous panniculitis-like T-cell lymphoma in the same patient. 179-184 10.1016/j.jdcr.2017.08.021 Wu Xinyu X Department of Pathology, Yale University School of Medicine, New Haven, Connecticut. Subtil Antonio A Department of Pathology, Yale (...) University School of Medicine, New Haven, Connecticut. Ko Christine C Department of Pathology, Yale University School of Medicine, New Haven, Connecticut. Department of Dermatology, Yale University School of Medicine, New Haven, Connecticut. eng Case Reports 2018 02 04 United States JAAD Case Rep 101665210 2352-5126 CT, computed tomography HPS, hemophagocytic syndrome LEP, lupus erythematosus panniculitis PET, positron emission tomography SPTCL, subcutaneous panniculitis-like T-cell lymphoma lupus

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2018 JAAD Case Reports

3. Panniculitis and vitiligo occurring during BRAF and MEK inhibitors combination in advanced melanoma patients: Potential predictive role of treatment efficacy. (PubMed)

Panniculitis and vitiligo occurring during BRAF and MEK inhibitors combination in advanced melanoma patients: Potential predictive role of treatment efficacy. Panniculitis and vitiligo-like lesions have been recently identified as rare cutaneous side effects of the combination of BRAF and MEK inhibitors, a standard of care in metastatic and locally advanced BRAF V600 mutated melanoma. An immune-mediated mechanism has been advocated in the pathogenesis of these skin lesions. Herein we (...) retrospectively reviewed our institutional experience with the aim to explore the association between the occurrence of panniculitis and vitiligo-like lesions during combination therapy with dabrafenib (D) and trametinib (T) and outcome of advanced melanoma patients. Among 52 consecutive BRAF V600 mutated melanoma patients submitted to DT in our center, 12 (23%) developed immune related skin lesions (IRSLs): 8 panniculitis and 4 vitiligo. Patients with IRSLs diagnosis obtained a better disease response (83

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2019 PLoS ONE

4. Useful Parameters for Distinguishing Subcutaneous Panniculitis-like T-Cell Lymphoma From Lupus Erythematosus Panniculitis. (PubMed)

Useful Parameters for Distinguishing Subcutaneous Panniculitis-like T-Cell Lymphoma From Lupus Erythematosus Panniculitis. Some cases of subcutaneous panniculitis-like T-cell lymphoma (SPTCL) and lupus erythematosus panniculitis (LEP) demonstrate clinical and histopathologic overlap, raising the possibility that they represent opposite ends of a disease spectrum. SPTCL, however, is typically associated with greater morbidity and risk for hemophagocytic lymphohistiocytosis (HLH); therefore

2016 American Journal of Surgical Pathology

5. Atypical lymphocytic lobular panniculitis: an overlap condition with features of subcutaneous panniculitis-like T-cell lymphoma and lupus profundus (PubMed)

Atypical lymphocytic lobular panniculitis: an overlap condition with features of subcutaneous panniculitis-like T-cell lymphoma and lupus profundus 27807018 2017 02 23 2018 11 13 1757-790X 2016 2016 Nov 02 BMJ case reports BMJ Case Rep Atypical lymphocytic lobular panniculitis: an overlap condition with features of subcutaneous panniculitis-like T-cell lymphoma and lupus profundus. bcr2016215335 10.1136/bcr-2016-215335 He Alice A http://orcid.org/0000-0002-1938-0619 Department of Dermatology (...) Antirheumatic Agents 4QWG6N8QKH Hydroxychloroquine Subcutaneous panniculitis-like T-cell lymphoma IM Antirheumatic Agents therapeutic use Biopsy Diagnosis, Differential Female Humans Hydroxychloroquine therapeutic use Lymphoma, T-Cell diagnosis drug therapy pathology Middle Aged Necrosis Panniculitis diagnosis drug therapy pathology Panniculitis, Lupus Erythematosus diagnosis drug therapy pathology Polymerase Chain Reaction Upper Extremity Conflicts of Interest: None declared. 2016 11 4 6 0 2017 2 24 6 0

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2016 BMJ case reports

6. Subcutaneous Panniculitis-Like T Cell Lymphoma Mimicking Early-Onset Nodular Panniculitis (PubMed)

Subcutaneous Panniculitis-Like T Cell Lymphoma Mimicking Early-Onset Nodular Panniculitis Subcutaneous panniculitis-like T cell lymphoma is a very uncommon subtype of cutaneous T cell lymphoma. The manifestations of this rare disease are atypical at onset, and may mimic some rheumatic or dermatologic diseases, which causes the delay of diagnosis and treatment.We report a 24-year-old man suffering from intermittent fever and skin nodules on the left anterior chest wall, who was initially (...) misdiagnosed with nodular panniculitis and finally diagnosed with subcutaneous panniculitis-like T cell lymphoma through repeat examination of biopsy of the skin nodule. Positron emission tomography revealed extracutaneous adipose tissue involvement. Subsequently, hemophagocytic syndrome occurred while under a conventional dose of glucocorticoid, but remission was induced by treatment with cyclosporine A and high doses of dexamethasone.In order to avoid the delay diagnosis and inappropriate treatment

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2016 The American journal of case reports

7. Epidemiology of primary cutaneous gamma/delta T-cell lymphoma and subcutaneous panniculitis-like T-cell lymphoma in the United States from 2006-2015: A Surveillance, Epidemiology, and End Results-18 analysis. (PubMed)

Epidemiology of primary cutaneous gamma/delta T-cell lymphoma and subcutaneous panniculitis-like T-cell lymphoma in the United States from 2006-2015: A Surveillance, Epidemiology, and End Results-18 analysis. Primary cutaneous gamma/delta T-cell lymphoma (pcGDTCL) is a rare, aggressive T-cell lymphoma that presents with ulcerated nodules, extranodal dissemination, constitutional symptoms, and often, hemophagocytic lymphohistiocytosis (HLH).1 pcGDTCL is so named given the gamma/delta phenotype

2019 British Journal of Dermatology

8. Late Pancreatic Panniculitis in a Simultaneous Pancreas Kidney Transplant patient with Failed Allografts. (PubMed)

Late Pancreatic Panniculitis in a Simultaneous Pancreas Kidney Transplant patient with Failed Allografts. We present a rare case of pancreatic panniculitis in a 59 year old male simultaneous pancreas kidney (SPK) recipient with failed allografts. Patient presented with fever and painful erythematous nodules on his leg 1 month after stopping all immunosuppression. A thorough infectious and rheumatological workup was negative. He had pancreas rejection 4 years after SKP transplant (...) and was restarted on dialysis after 14 years when his renal allograft failed due to chronic allograft nephropathy. His chronic immunosuppression (tacrolimus, azathioprine) was stopped and prednisone was weaned over 3 months at that time. A skin biopsy revealed saponification of the subcutaneous fat with inflammation pathognomonic of pancreatic panniculitis. Concurrent allograft pancreatitis confirmed with elevated Lipase and a CT scan finding of peri-pancreatic graft stranding and atrophic native pancreas. He

2019 American Journal of Transplantation

9. Approach to the diagnosis and treatment of mesenteric panniculitis from the surgical point of view (PubMed)

Approach to the diagnosis and treatment of mesenteric panniculitis from the surgical point of view To evaluate the diagnostic and treatment approaches for patients diagnosed with mesenteric panniculitis.We retrospectively reviewed all patients diagnosed with mesenteric panniculitis between January 2010 and March 2016. We recorded the demographic features, clinical symptoms, laboratory values, radiological methods, treatment approach, and outcomes of the patients.We evaluated 22 patients (17 (...) outpatient treatment. No complication associated with hospitalization or during outpatient follow-up period was observed.Mesenteric panniculitis can be successfully treated conservatively without surgical intervention. Clinical doubt is of great importance for diagnosis, and plausible underlying malignancy should be kept in mind.

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2018 Turkish Journal of Surgery

10. Dermatomyositis panniculitis: A clinico-pathologic and immunohistochemical study of 18 cases. (PubMed)

Dermatomyositis panniculitis: A clinico-pathologic and immunohistochemical study of 18 cases. Panniculitis occurring in dermatomyositis is uncommon, with only a few cases described in the literature, most of them as case reports.This report describes the clinicopathological and immunohistochemical findings in a series of 18 patients with panniculitis associated with dermatomyositis.In each patient, we collected the clinical data of the cutaneous lesions as well as the characteristic clinical (...) and laboratory findings. A series of histopathologic findings was recorded in the biopsy of each patient. A panel of antibodies was used in some cases to investigate the immunophenotype of the infiltrate. Data of treatment and follow-up were also collected.Of the 18 patients, 13 were female and 5 were male, ranging in age from 13 to 74 years (median, 46.4 years). In addition to panniculitis, all patients presented pathognomonic cutaneous findings of DM and reported proximal muscle weakness prior

2018 Journal of the European Academy of Dermatology and Venereology

11. Lupus erythematosus panniculitis in a 10-year-old female child with severe systemic lupus erythematosus: A case report. (PubMed)

Lupus erythematosus panniculitis in a 10-year-old female child with severe systemic lupus erythematosus: A case report. Lupus erythematosus panniculitis (LEP) is a rare subset of lupus erythematosus. The incidence of LEP in systemic lupus erythematosus (SLE) ranges from 2% to 5%. In the previous literature, most LEP patients were women aged from 20 to 60 years, while pediatric cases were rare, all of whom appeared on their own without SLE.A rare LEP in a 10-year-old female child with severe SLE

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2018 Medicine

12. Inherited Immunodeficiency: A New Association With Early-Onset Childhood Panniculitis. (PubMed)

Inherited Immunodeficiency: A New Association With Early-Onset Childhood Panniculitis. We report on 4 children who presented with aseptic panniculitis associated with inherited immunodeficiency. Three patients had a B-cell immunodeficiency resulting from mutations in the TRNT1 and NF-κb2 genes (no mutation was found in the third patient), and 1 had a T-cell deficiency (mutation in the LCK gene). Panniculitis occurred before the age of 2 years in the 4 patients and preceded the onset (...) of recurrent infections because of immunodeficiency in 2. It presented either as nodules, which resolved spontaneously within 1 to 2 weeks (3 patients), or chronic ulcerative lesions (1 patient) associated with unexplained fever and elevated acute phase reactants, without evidence of infection or high-titer autoantibodies. Febrile nodules relapsed in 2 patients, and recurrent attacks of unexplained fever (without relapse of panniculitis) occurred in the third. Skin biopsy revealed predominantly lympho

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2018 Pediatrics

13. Chronic pancreatitis with multiple pseudocysts and pancreatic panniculitis: A case report. (PubMed)

Chronic pancreatitis with multiple pseudocysts and pancreatic panniculitis: A case report. Pancreatic pseudocyst can present single or multiple, inside or outside the pancreas. Pancreatic panniculitis is a rare skin lesion in pancreatic disease patients. The purpose of this study is to report a case of chronic pancreatitis coexisting with multiple pseudocysts and pancreatic panniculitis.A 46-year-old man with chronic pancreatitis presented multiple small cystic lesions inside the head (...) of the pancreas and two large cystic lesions adjacent to the tail of the pancreas. The patient also developed subcutaneous nodules involving upper and lower limbs, hands, and lower abdomen bilaterally.The patient was diagnosed with pancreatic pseudocyst and pancreatic panniculitis resulted from chronic pancreatitis.Bile duct stent and pancreatic duct stent placement was performed endoscopicly.Panniculitis faded three weeks later and the pancreatic pseudocysts disappeared six weeks later.Clinicians should

2018 Medicine

14. Mesenteric Panniculitis-First Case Series After Bariatric Surgery. (PubMed)

Mesenteric Panniculitis-First Case Series After Bariatric Surgery. Mesenteric panniculitis is an uncommon pathology, of poorly understood etiology, characterized by progressive inflammation and fibrosis of the small bowel mesentery. This disease has been reported usually after other abdominal surgeries. We present two cases of young male patients who underwent laparoscopic sleeve gastrectomy and developed abdominal symptoms within 45-60 days of surgery. Both were investigated for known post (...) -bariatric complications. While first patient presented (5 months later) at an irreversible stage and died within 8-9 months of primary surgery, in second patient, the disease process could be reversed through early intervention, diagnosis, treatment, and compliance. Mesenteric panniculitis is a rapidly progressive entity, which can be adequately treated by early identification and long-term immune-suppressive therapy.

2018 Obesity Surgery

15. Pancreatic panniculitis: the "bright" side of the moon in solid cancer patients. (PubMed)

Pancreatic panniculitis: the "bright" side of the moon in solid cancer patients. Pancreatic panniculitis is a rare complication of pancreas disorders occurring in 0.3-3% of patients, most often accompanied by the pancreatic acinar carcinoma. It presents multiple, painful, deep, ill-defined, red-brown, migratory nodules and plaques of hard elastic consistency; often ulcerated and typically located on the lower proximal and distal extremities. The pathogenesis is not fully understood (...) , but it is thought to result from lipolysis and fat necrosis with secondary tissue inflammation induced by pancreatic enzymes. Histopathology shows subcutaneous lobular fat necrosis with anuclear adipocytes (called ghost cells) surrounded by a mixed inflammatory infiltrate. Focal calcification may also be seen. The treatment is directed to the underlying disorder, which may result in regression of skin lesions.We present two cases of pancreatic panniculitis with similar clinical, laboratory

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2018 BMC Gastroenterology

16. Breast panniculitis with liquefactive fat necrosis: A case report (PubMed)

Breast panniculitis with liquefactive fat necrosis: A case report Panniculitis is a group of heterogeneous disorders characterized by inflammation of the subcutaneous adipose tissue. Panniculitis of breast tissue as the initial manifestation has rarely been reported and is often misdiagnosed. Breast panniculitis may cause substantial morbidity and early diagnosis and treatment are important for the prognosis of the disease. The present study has reported a case of panniculitis with inflammation (...) of the mammary glands as the initial presentation and provided a detailed description of ultrasonography, X-ray, computed tomography, magnetic resonance imaging and other imaging features of breast panniculitis. The treatment and follow-up were also described. Following treatment with systemic corticosteroids combined with methotrexate and thalidomide for 2 months, the breast appeared to be normal without scar formation. The present case report provides a good reference for the future diagnosis and treatment

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2018 Experimental and therapeutic medicine

17. An Autopsy Case of Mesenteric Panniculitis with Massive Pleural Effusions (PubMed)

An Autopsy Case of Mesenteric Panniculitis with Massive Pleural Effusions BACKGROUND Mesenteric panniculitis (MP) is an idiopathic chronic inflammatory condition of the mesentery. The main symptoms include abdominal pain, abdominal distention, weight loss, fever, nausea, and vomiting. The patients also present with chylous ascites in 14% of the cases and chylous pleural effusion (CPE) in very rare occasions. Despite the previous view of excellent prognosis of MP, two recent papers reported

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2018 The American journal of case reports

18. Cold panniculitis: Adverse cutaneous effect of whole-body cryotherapy (PubMed)

Cold panniculitis: Adverse cutaneous effect of whole-body cryotherapy 29693065 2019 02 26 2352-5126 4 4 2018 May JAAD case reports JAAD Case Rep Cold panniculitis: Adverse cutaneous effect of whole-body cryotherapy. 344-345 10.1016/j.jdcr.2018.02.010 Greenwald Elizabeth E Ronald O. Perelman Department of Dermatology, New York University School of Medicine, New York, New York. Christman Mitalee M Ronald O. Perelman Department of Dermatology, New York University School of Medicine, New York, New (...) effect cold panniculitis whole-body cryotherapy 2018 4 26 6 0 2018 4 26 6 0 2018 4 26 6 1 epublish 29693065 10.1016/j.jdcr.2018.02.010 S2352-5126(18)30051-1 PMC5911975 Dermatol Clin. 2008 Oct;26(4):485-9, vii 18793981 Cochrane Database Syst Rev. 2015 Sep 18;(9):CD010789 26383887 Clin J Sport Med. 2017 Sep;27(5):e67-e68 28829347 BMJ Case Rep. 2017 Oct 13;2017:null 29030365

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2018 JAAD Case Reports

19. Recurrent lupus profundus-like panniculitis associated with streptococcal throat infections in an immunocompetent child (PubMed)

Recurrent lupus profundus-like panniculitis associated with streptococcal throat infections in an immunocompetent child 29693070 2019 02 26 2352-5126 4 4 2018 May JAAD case reports JAAD Case Rep Recurrent lupus profundus-like panniculitis associated with streptococcal throat infections in an immunocompetent child. 359-361 10.1016/j.jdcr.2017.10.010 Min Michelle S MS Icahn School of Medicine at Mount Sinai, New York, New York. Boston University School of Medicine, Boston, Massachusetts. Phelps (...) Robert R Icahn School of Medicine at Mount Sinai, New York, New York. Levitt Jacob J Icahn School of Medicine at Mount Sinai, New York, New York. eng Case Reports 2018 04 04 United States JAAD Case Rep 101665210 2352-5126 EN, erythema nodosum LEP, lupus erythematosus profundus SLE, systemic lupus erythematosus Streptococcus infection lupus erythematosus profundus panniculitis 2018 4 26 6 0 2018 4 26 6 0 2018 4 26 6 1 epublish 29693070 10.1016/j.jdcr.2017.10.010 S2352-5126(17)30262-X PMC5911798

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2018 JAAD Case Reports

20. Mesenteric Panniculitis Presenting as Fever of Unknown Etiology in a Patient with History of Abdominal Surgery (PubMed)

Mesenteric Panniculitis Presenting as Fever of Unknown Etiology in a Patient with History of Abdominal Surgery Mesenteric panniculitis is characterized by nonspecific fibrous inflammation of the small bowel mesentery, appendix, and mesoappendix. Clinical course is usually benign and outcome is favorable. We report a case of mesenteric panniculitis presenting as fever of unknown etiology in a patient with history of abdominal surgery.

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2018 Case reports in gastrointestinal medicine

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