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Panic Disorder

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1. Panic disorders

Panic disorders Panic disorders - Symptoms, diagnosis and treatment | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  Panic disorders Last reviewed: February 2019 Last updated: January 2019 Summary Characterised by recurring expected or unexpected panic attacks, worry about future attacks over a 1-month period, and changes in behaviour as a consequence of the attacks. Frequency of panic attacks may vary considerably, with some individuals reporting brief (...) clusters of several panic episodes in a short period of time, weekly panic attacks, or periodic attacks over the course of several months. Higher risk among first-degree relatives; onset of attacks triggered by stress; often comorbid with other anxiety, mood, and substance-use disorders. Assessment is made through ruling out organic causes; self-report; clinical interview; and behavioural observation. Selective serotonin-reuptake inhibitors, serotonin-noradrenaline reuptake inhibitors, and cognitive

2019 BMJ Best Practice

2. Panic disorders

Panic disorders Panic disorders - Symptoms, diagnosis and treatment | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  Panic disorders Last reviewed: February 2019 Last updated: January 2019 Summary Characterised by recurring expected or unexpected panic attacks, worry about future attacks over a 1-month period, and changes in behaviour as a consequence of the attacks. Frequency of panic attacks may vary considerably, with some individuals reporting brief (...) clusters of several panic episodes in a short period of time, weekly panic attacks, or periodic attacks over the course of several months. Higher risk among first-degree relatives; onset of attacks triggered by stress; often comorbid with other anxiety, mood, and substance-use disorders. Assessment is made through ruling out organic causes; self-report; clinical interview; and behavioural observation. Selective serotonin-reuptake inhibitors, serotonin-noradrenaline reuptake inhibitors, and cognitive

2018 BMJ Best Practice

4. Development of a very brief scale for detecting and measuring panic disorder using two items from the Panic Disorder Severity Scale-Self Report. Full Text available with Trip Pro

Development of a very brief scale for detecting and measuring panic disorder using two items from the Panic Disorder Severity Scale-Self Report. To minimize the burden in detecting and monitoring Panic Disorder and Agoraphobia by developing a very brief scale with selected items from the Panic Disorder Severity Scale-Self Report (PDSS-SR), and to investigate the proposed scale's psychometric properties in a comorbid sample.A sample of 5103 patients from the Internet Psychiatry Clinic in Sweden (...) , diagnosed and treated with Internet-based cognitive behavioral therapy for panic disorder (n = 1390), social anxiety disorder (n = 1313) or depression (n = 2400), responded to the PDSS-SR. Six criteria related to factor structure, sensitivity to change and clinical representativeness were used to select items. Psychometric analyses for the selected very brief scale were performed.Items 2 (distress during panic attacks) and 4 (agoraphobic avoidance), were selected to create the very brief PDSS-SR version

2019 Journal of Affective Disorders

5. Assessing vulnerability to panic: a systematic review of reactivity in biological challenge paradigms as a prospective predictor of panic attacks and panic disorder

Assessing vulnerability to panic: a systematic review of reactivity in biological challenge paradigms as a prospective predictor of panic attacks and panic disorder Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability (...) species); sex (stratified per sex); duration of index ischemia (linear); stem cell dose (linear); blinding of outcome assessment reported (stratified yes vs no). For stratified analyses, a minimum number of 8 studies per subgroup is required. ">Subgroup analyses A sensitivity analysis is conducted to assess the impact of decisions taken in the review process on the meta-analysis outcome. These decisions may have been made in various stages of the review, e.g. the decision to exclude certain disease

2020 PROSPERO

6. Miscellaneous: Short-term efficacy of psychological and psychopharmacological interventions for panic disorder appears not to be different

Miscellaneous: Short-term efficacy of psychological and psychopharmacological interventions for panic disorder appears not to be different Short-term efficacy of psychological and psychopharmacological interventions for panic disorder appears not to be different | Evidence-Based Mental Health We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see (...) our . Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Short-term efficacy of psychological and psychopharmacological interventions for panic disorder appears not to be different

2017 Evidence-Based Mental Health

7. Antidepressants and benzodiazepines for panic disorder in adults. Full Text available with Trip Pro

Antidepressants and benzodiazepines for panic disorder in adults. A panic attack is a discrete period of fear or anxiety that has a rapid onset, reaches a peak within 10 minutes and in which at least four of 13 characteristic symptoms are experienced, including racing heart, chest pain, sweating, shaking, dizziness, flushing, stomach churning, faintness and breathlessness. Panic disorder is common in the general population with a lifetime prevalence of 1% to 4%. The treatment of panic disorder (...) includes psychological and pharmacological interventions. Amongst pharmacological agents, antidepressants and benzodiazepines are the mainstay of treatment for panic disorder. Different classes of antidepressants have been compared; and the British Association for Psychopharmacology, and National Institute for Health and Care Excellence (NICE) consider antidepressants (mainly selective serotonin reuptake inhibitors (SSRIs)) as the first-line treatment for panic disorder, due to their more favourable

2016 Cochrane

8. CBT for panic disorder

CBT for panic disorder RACGP - CBT for panic disorder Search Become a student member today for free and be part of the RACGP community A career in general practice Starting the GP journey Enrolments for the 2019.1 OSCE FRACGP exams closing 29 March 2019 Fellowship FRACGP exams Research Practice Experience Program is a self-directed education program designed to support non vocationally registered doctors on their pathway to RACGP Fellowship Fellowship International graduates FRACGP exams RACGP (...) Releases 2013 Media Releases 2012 Media Releases Search CBT for panic disorder CBT for panic disorder Introduction Panic disorder affects approximately 10% of general practice patients. Intervention Cognitive behavioural therapy (CBT), which is a multimodal psychotherapy. Specific techniques used in CBT for panic disorder include: psychoeducation breathing retraining progressive muscle relaxation cognitive restructuring behavioural experiments interoceptive exposure and in vivo exposure. CBT

2016 Handbook of Non-Drug interventions (HANDI)

9. Epidemiology of panic attacks, panic disorder and the moderating role of age: Results from a population-based study. (Abstract)

Epidemiology of panic attacks, panic disorder and the moderating role of age: Results from a population-based study. The aim of this study was to investigate the prevalence of panic attacks (PA) and panic disorder (PD) over the lifespan, determine the main correlates and analyze the potential moderating role of age.We analyzed cross-sectional data from a nationally-representative sample of 4,569 non-institutionalized adults. Three panic groups were created according to results in the CIDI (...) interview: non-panic, PA (without PD) and PD. Panic groups were used as outcomes in adjusted multinomial regression models where several correlates were investigated. Interactions between each covariate and age were explored.The highest prevalence rates of PA (9.5%) and PD (3.3%) were found in people aged 30-39 and 40-49, respectively. Respondents aged 80 + presented the lowest rates. In the adjusted multinomial model, younger ages, having depression, and poorer levels of quality of life were

2018 Journal of Affective Disorders

10. Twelve-Month Outcomes Following Successful Panic-Focused Psychodynamic Psychotherapy, Cognitive-Behavioral Therapy, or Applied Relaxation Training for Panic Disorder. (Abstract)

Schedule.Patients with panic disorder who responded to 1 of 3 treatments maintained their gains on the PDSS, SDS, and HDRS with no differences by condition in rates of change over the follow-up period (all P values ≥ .20). Similarly, 57% of improved patients did not have a panic disorder diagnosis by the end of 1 year, regardless of the treatment received. No differences in rates of panic disorder diagnosis were found across treatment conditions at either 6 months or 12 months (all P values ≥ .78). Results (...) Twelve-Month Outcomes Following Successful Panic-Focused Psychodynamic Psychotherapy, Cognitive-Behavioral Therapy, or Applied Relaxation Training for Panic Disorder. Given the chronic, episodic nature of panic disorder, it is important to examine long-term outcomes of patients who respond well to various psychotherapies.Out of 116 patients with DSM-IV panic disorder who evidenced a ≥ 40% reduction in panic and avoidance symptoms on the Panic Disorder Severity Scale (PDSS) after 12-14 weeks

2018 Journal of Clinical Psychiatry Controlled trial quality: uncertain

11. Cardiorespiratory concerns shape brain responses during automatic panic-related scene processing in patients with panic disorder. Full Text available with Trip Pro

Cardiorespiratory concerns shape brain responses during automatic panic-related scene processing in patients with panic disorder. Increased automatic processing of threat-related stimuli has been proposed as a key element in panic disorder. Little is known about the neural basis of automatic processing, in particular to task-irrelevant, panic-related, ecologically valid stimuli, or about the association between brain activation and symptomatology in patients with panic disorder.The present (...) event-related functional MRI (fMRI) study compared brain responses to task-irrelevant, panic-related and neutral visual stimuli in medication-free patients with panic disorder and healthy controls. Panic-related and neutral scenes were presented while participants performed a spatially nonoverlapping bar orientation task. Correlation analyses investigated the association between brain responses and panic-related aspects of symptomatology, measured using the Anxiety Sensitivity Index (ASI).We

2018 Journal of Psychiatry & Neuroscience

12. A Multi-Site RCT of a Stepped-Care Intervention for Emergency Department Patients With Panic Attacks and Panic Disorder

disorder in the A&E and discharge (routine care). In addition to the baseline assessment, the study follow-up visits will occur at 1, 3, 6, and 12 months. Condition or disease Intervention/treatment Phase Panic Attacks and Disorders Behavioral: Stepped Care Intervention (STEP) Diagnostic Test: Screening only Not Applicable Detailed Description: Specific Aims and Hypotheses Aim 1 (Primary): To evaluate the clinical effectiveness of a stepped-care intervention for A&E patients with panic attacks (...) to assess global severity of symptoms.The CGI ranges from 1 (normal, not at all ill) to 7 (among the most extremely ill patients). A higher total value indicates more severe panic symptoms and anxiety. Panic Disorder Module of the Structured Clinical Interview for DSM-5 (SCID; First et al., 2015) [ Time Frame: Baseline, 1st month, 3rd month, 6th month, 12th month ] The SCID is the gold standard tool for the reliable diagnosis of Axis I psychiatric disorders in clinical populations. Eligibility Criteria

2018 Clinical Trials

13. Ratio of plasma BDNF to leptin levels are associated with treatment response in major depressive disorder but not in panic disorder: A 12-week follow-up study. (Abstract)

Ratio of plasma BDNF to leptin levels are associated with treatment response in major depressive disorder but not in panic disorder: A 12-week follow-up study. A link between brain-derived neurotrophic factor (BDNF) expression and the mood regulatory effect of leptin has been suggested in the pathophysiology of major depressive disorder (MDD). We investigated treatment response and pre-treatment leptin and BDNF in patients with MDD and with panic disorder (PD).We recruited 41 patients with MDD

2019 Journal of Affective Disorders

14. Impaired discriminative fear conditioning during later training trials differentiates generalized anxiety disorder, but not panic disorder, from healthy control participants Full Text available with Trip Pro

Impaired discriminative fear conditioning during later training trials differentiates generalized anxiety disorder, but not panic disorder, from healthy control participants Fear conditioning is implicated as a central psychopathological mechanism of anxiety disorders. People with anxiety disorders typically demonstrate reduced affective discrimination between conditioned danger and safety cues. Here, affective discrimination refers to the ability to selectively display fear to dangerous (...) but not safe situations. Though both generalized anxiety disorder (GAD) and panic disorder (PD) are linked to impaired affective discrimination, the clinical phenomenology of these disorders suggests that people with GAD versus PD might be less able to overcome such deficits. It is unclear how this potential difference would manifest during lab-based conditioning.We used a classical fear conditioning paradigm over two discrimination training sessions to examine whether those with GAD, but not PD, would

2018 Comprehensive psychiatry

15. Internet-Based Cognitive Behavioral Therapy With Real-Time Therapist Support via Videoconference for Patients With Obsessive-Compulsive Disorder, Panic Disorder, and Social Anxiety Disorder: Pilot Single-Arm Trial. Full Text available with Trip Pro

Internet-Based Cognitive Behavioral Therapy With Real-Time Therapist Support via Videoconference for Patients With Obsessive-Compulsive Disorder, Panic Disorder, and Social Anxiety Disorder: Pilot Single-Arm Trial. Cognitive behavioral therapy (CBT) is the first-line treatment for adults with obsessive-compulsive disorder (OCD), panic disorder (PD), and social anxiety disorder (SAD). Patients in rural areas can access CBT via the internet. The effectiveness of internet-delivered cognitive (...) of a therapist, using tablet personal computer (Apple iPad Mini 2). Treatment involved individualized CBT formulations specific to the presenting diagnosis; all sessions were provided by the same therapist. The primary outcomes were reduction in symptomatology, using the Yale-Brown obsessive-compulsive scale (Y-BOCS) for OCD, Panic Disorder Severity Scale (PDSS) for PD, and Liebowitz Social Anxiety Scale (LSAS) for SAD. The secondary outcomes included the EuroQol-5 Dimension (EQ-5D) for Quality of Life

2018 Journal of medical Internet research

16. Panic disorder in people with bipolar disorder: very common, but treatment options limited

Panic disorder in people with bipolar disorder: very common, but treatment options limited Panic disorder bipolar disorder Search National Elf Service Search National Elf Service » » » » Panic disorder in people with bipolar disorder: very common, but treatment options limited Aug 15 2018 Posted by Anxiety disorders are frequently comorbid with depression, but there is also evidence of a strong association with bipolar disorder. Indeed, symptoms of anxiety are often present before the onset (...) are lacking. A recent paper by Preti et al (2018) aimed to systematically review the literature for papers reporting on comorbid panic disorder in bipolar disorder and performed meta-analyses for of the comorbidity. Panic disorder is an anxiety disorder where you regularly have sudden attacks of panic or fear. Methods Preti et al conducted a systematic literature search using the PubMed/MEDLINE database for all studies with primary data on patients with bipolar disorder and a comorbid diagnosis of panic

2018 The Mental Elf

17. Thalamic shape and volume abnormalities in female patients with panic disorder. Full Text available with Trip Pro

Thalamic shape and volume abnormalities in female patients with panic disorder. The thalamus is believed to play crucial role in processing viscero-sensory information, and regulating the activity of amygdala in patients with panic disorder (PD). Previous functional neuroimaging studies have detected abnormal activation in the thalamus in patients with PD compared with healthy control subjects (HC). Very few studies, however, have investigated for volumetric abnormalities in the thalamus

2018 PLoS ONE

18. Early intervention for subthreshold panic disorder in the Netherlands: A model-based economic evaluation from a societal perspective. Full Text available with Trip Pro

Early intervention for subthreshold panic disorder in the Netherlands: A model-based economic evaluation from a societal perspective. Panic disorder (PD) is associated with impaired functioning and reduced quality of life. In the Netherlands, almost 2% of the population experiences clinically relevant panic symptoms without meeting the diagnostic criteria for PD, which is referred to as subthreshold PD (STHPD). Evidence suggests that subthreshold mental disorders may have a similar impact (...) on quality of life and functioning in comparison with full-blown mental disorders, which draws attention to the need for interventions for STHPD. These interventions are currently not systematically provided in clinical practice. This study aims to investigate the population cost-effectiveness of adding a CBT-based early intervention for adults with STHPD to the existing health care for people with PD in the Netherlands.A health-economic Markov model was constructed in order to compare quality adjusted

2018 PLoS ONE

19. Value of information analysis of an early intervention for subthreshold panic disorder: Healthcare versus societal perspective. Full Text available with Trip Pro

Value of information analysis of an early intervention for subthreshold panic disorder: Healthcare versus societal perspective. Panic disorder is associated with high productivity costs. These costs, which should be included in cost-effectiveness analyses (CEA) from a societal perspective, have a considerable impact on cost-effectiveness estimates. However, they are often omitted in published CEAs. It is therefore uncertain whether choosing a societal perspective changes priority setting (...) in future research as compared to a healthcare perspective.To identify research priorities regarding the cost-effectiveness of an early intervention for subthreshold panic disorder using value of information (VOI) analysis and to investigate to what extent priority setting depends on the perspective.We calculated the cost-effectiveness of an early intervention for panic disorder from a healthcare perspective and a societal perspective. We performed a VOI analysis, which estimates the expected value

2018 PLoS ONE

20. Smaller volumes in the lateral and basal nuclei of the amygdala in patients with panic disorder. Full Text available with Trip Pro

Smaller volumes in the lateral and basal nuclei of the amygdala in patients with panic disorder. The amygdala plays an important functional role in fear and anxiety. Abnormalities in the amygdala are believed to be involved in the neurobiological basis of panic disorder (PD). Previous structural neuroimaging studies have found global volumetric and morphological abnormalities in the amygdala in patients with PD. Very few studies, however, have explored for structural abnormalities in various

2018 PLoS ONE

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